Gene ADCK1 (Mouse)

ADCK1

Species: Mouse
Alias: 2610005A10Rik, ADCK1
External Links: MGI , Entrez Gene , Refseq cDNA , Refseq Protein , Phosphosite , iHOP
Annotation:

Classification

Group: Atypical
Family: ABC1
Subfamily: ABC1-B

Sequence

Name Sequence Type Origin Length Description Download
ADCK1.kin_dom Protein Kinase Domain None 307 None Fasta, JSON
ADCK1.AA Protein Sugen 525 None Fasta, JSON
ADCK1.NA RNA Sugen 2158 None Fasta, JSON

Protein domain

Protein domains of ADCK1.AA. The domains are annotated by HMM profiles from Pfam and SMART, as well as in-house data which includes HMMs of each individual kinase group, family and subfamily. Here is domain list in details, including sequence identity, significance and alignment. In particular, you can find can find the best hit kinase group/family/subfamily, which is helpful to understand the relationship between kinases.Kinase domain and best hit kinase group/family/subfamily are highlighted in red and blue. Visualized by pviz.

Usage: Zoom in selected region by dragging mouse and zoom out by double-clicking.

Show/hide domain list
Domain Protein name Domain Name Range Identity (%) Significance Score Profile Source Profile Range (length) Alignment
Kinase ADCK1.AA ABC1-B 136-252 54 3.7e-73 249.36 In-house 1-125 (125) Show / Hide 
Range on Protein: 136-252
Range on HMM: 1-125/125
Sequence Identity: 54% (69 aa)

EDLGKEIHDLFLSFDDTPLGAASLAQVHKAVLHDGRTVAVKVQHPKVQAQSSKDILLMEVLVLAVKQLFP------DFEFMWLVDEAKKNLPLELDFLNE
.|||  | | |  ||..|..||||||||.|.||||.|||||||||....|...|...||..| .....||      .|.|||..||..|||| ||||.||
KDLG-NIEDVFSEFDQKPIAAASLAQVHRAKLHDGETVAVKVQHPWLRKQFHYDMMMMELFVKVCDWFFPKSPDFKEFPFMWFHDEIQKNLPQELDFYNE

GRNAEKVAHMLR---HFDFLKVPQIH
.|||||...|..   |||||.||.||
ARNAEKCRQMFKKFKHFDFLYVPRIH
Kinase ADCK1.AA ABC1 136-252 50 1.3e-67 230.89 In-house 1-123 (123) Show / Hide 
Range on Protein: 136-252
Range on HMM: 1-123/123
Sequence Identity: 50% (62 aa)

EDLGKEIHDLFLSFDDTPLGAASLAQVHKAVLHDGRTVAVKVQHPKVQAQSSKDILLMEVLVLAVKQLFP-----DFEFMWLVDEAKKNLPLELDFLNEG
.|||  . | | .||..|..|||.||||.|.|.||.|||||||||.|..|...||..||..| .....||     .|..||.|||..|.||.|.||.||.
QDLG-NWEDVFSEFDEKPFAAASIAQVHRAKLKDGQTVAVKVQHPGVREQIHYDINNMEMVVKMCDWFFPGPDFKWFFLMWFVDEFQKELPWECDFNNEA

RNAEKVAHMLR--HFDFLKVPQIH
|||||......  |..|..||.||
RNAEKCRQLFKKFHWPFFYVPRIH
Kinase ADCK1.AA ABC1 136-252 42 1.3e-62 212.8 Pfam 1-126 (126) Show / Hide 
Range on Protein: 136-252
Range on HMM: 1-126/126
Sequence Identity: 42% (54 aa)

EDLGKEIHDLFLSFDDTPLGAASLAQVHKAVLHD-GRTVAVKVQHPKVQAQSSKDILLMEVLVLAVKQLFPD-----FEFMWLVDEAKKNLPLELDFLNE
|.||. ....| .||..|..|||.||||.|.|.| |..|||||||| |. ....|| .|.... .||..||.     |..||.|||..|||| |||...|
EELGCPWEEIFQEFDEEPIAAASIAQVHRARLKDDGEEVAVKVQHPGVKKRMMRDIYNMRWMAKWVKRFFPGYRRQRFDLMWIVDEFRKNLPWELDYRRE

GRNAEKVAHMLRHF---DFLKVPQIH
..|.|......||.   ....||...
AKNMERFRENFRHWHRQPWVYVPKVY
Kinase ADCK1.AA ABC1-A 149-268 36 9.5e-18 58.13 In-house 1-120 (216) Show / Hide 
Range on Protein: 149-268
Range on HMM: 1-120/216
Sequence Identity: 36% (45 aa)

FDDTPLGAASLAQVHKAVLHDGRTVAVKVQHP--KVQAQSSKDILLMEVLVLAV--KQLFPDFEFMWLVDEAKKNLPLELDFLNEGRNAEKVAHMLRHFD
| . |  .||  |||.||| ||| ||||.| |  .   .|  . |.|   . ..  |..|.|     ..| |.. | .| |   | | . |   .|    
FEEMPFACASIGQVHQAVLKDGREVAVKIQYPGVAESIDSDINNLMMVMNMSGMFPKGMFLD----HFIDYARRELHWECDYQREARCMQKFRQLLKDWP

FLKVPQIHWELSTKRVLLMEFVEG
|  || .  |..| ||| || ..|
FFYVPHVIDEYCTDRVLTMELMYG
Kinase ADCK1.AA ABC1-C 294-316 65 3.9e-07 17.84 In-house 124-146 (307) Show / Hide 
Range on Protein: 294-316
Range on HMM: 124-146/307
Sequence Identity: 65% (15 aa)

MYSEMIFVNGFVHCDPHPGNVLV
|   ||||  ||| | ||||.||
MLLKMIFVDNFVHADLHPGNILV
Kinase ADCK1.AA ABC1-C 173-195 56 1.1e-05 13.18 In-house 1-23 (307) Show / Hide 
Range on Protein: 173-195
Range on HMM: 1-23/307
Sequence Identity: 56% (13 aa)

VAVKVQHPKVQAQSSKDILLMEV
||||| || . ||   |.||| .
VAVKVLHPGLLAQVHMDLLLMKI
Kinase ADCK1.AA S_TKc 148-426 12 3.3e-05 -100.58 SMART 1-231 (231) Show / Hide 
Range on Protein: 148-426
Range on HMM: 1-231/231
Sequence Identity: 12% (40 aa)

SFDDTPLGAASLAQVHKAVLHD-GRTVAVKVQHPKVQAQSSKDILLMEVLVLAVKQLFPDFEFMWLVDEAKKNLPLELDFLNEGRNAEKVAHMLRHFDFL
     ..|  . ..|.|.. .. || ||.|. .                                      ...  |.. | .  . . . ... .|.  
YEILRKIGKGAFGKVYKCRHKKTGRIVAIKIIK--------------------------------------EHIRREIQILKK--HHPNIVKLYDVFQD-

KVPQIHWELSTKRVLLMEFVEG--GQVNDRAYMEKNQ-----IDVNEISCHLGKMYSEMIFV--NGFVHCDPHPGNVLVRKRPDTGKAEIVLLDHGLYQV
          ..  . ||...|  | . |.    . .     ..  .. . .  . . . .   .|..|.|  | |.|. .       .| . | ||  .
----------DHLYMVMEYCDGDLGDLFDYIKKRGRHGLRFPFPE-HARFYMYQICCALEYCHSHGIIHRDLKPENILLDE-------HIKICDFGLARQ

LTEEFRLDYCHLWQSLIWTDMDG---------LKQYSQRLG--AADLYPL---FACMLTARS-WDSVKQGIGQAPVSATEDSEIR---NNAACYLPE---
|                 | . |         |       |  ..| . .   .. ||. .  ..   | . .  .    ..| .   ..  .. ||   
L-----------------TTFCGTPWYMAPEVL-----GYGKCKCDWWSCGCILYEMLCGYPPFP-QMQMMFKKIG----SPEAKDFIRKCLQKDPEKRP

-ISQLLN-------HVPR
 . ..|.       |   
TA-EALQDEWDIKCHPWF