Gene ADCK2 (Mouse)

ADCK2

Species: Mouse
Alias: BB006057, ADCK2
External Links: MGI , Entrez Gene , Refseq cDNA , Refseq Protein , Phosphosite , iHOP
Annotation:

Classification

Group: Atypical
Family: ABC1
Subfamily: ABC1-C

Sequence

Name Sequence Type Origin Length Description Download
ADCK2.kin_dom Protein Kinase Domain None 307 None Fasta, JSON
ADCK2.NA RNA Sugen 3539 None Fasta, JSON
ADCK2.AA Protein Sugen 617 None Fasta, JSON

Protein domain

Protein domains of ADCK2.AA. The domains are annotated by HMM profiles from Pfam and SMART, as well as in-house data which includes HMMs of each individual kinase group, family and subfamily. Here is domain list in details, including sequence identity, significance and alignment. In particular, you can find can find the best hit kinase group/family/subfamily, which is helpful to understand the relationship between kinases.Kinase domain and best hit kinase group/family/subfamily are highlighted in red and blue. Visualized by pviz.

Usage: Zoom in selected region by dragging mouse and zoom out by double-clicking.

Show/hide domain list
Domain Protein name Domain Name Range Identity (%) Significance Score Profile Source Profile Range (length) Alignment
Kinase ADCK2.AA Ciliate-E2c 200-217 38 0.000981 9.07 In-house 1-18 (310) Show / Hide 
Range on Protein: 200-217
Range on HMM: 1-18/310
Sequence Identity: 38% (7 aa)

FETREPVGSGCVAQVYKA
... ...|||  ..||||
IDRNNILGSGSYGKVYKA
Kinase ADCK2.AA ABC1 203-217 40 19.341179 0.4 Pfam 16-30 (126) Show / Hide 
Range on Protein: 203-217
Range on HMM: 16-30/126
Sequence Identity: 40% (6 aa)

REPVGSGCVAQVYKA
.||....  |||..|
EEPIAAASIAQVHRA
Kinase ADCK2.AA ABC1-C 299-605 83 1.4e-244 774.1 In-house 1-307 (307) Show / Hide 
Range on Protein: 299-605
Range on HMM: 1-307/307
Sequence Identity: 83% (257 aa)

VAVKVLHPGLLSQVSMDLLLMKIGSKALGLLPGVKWLSLPEIVEEFEKLMVQQTDLRYEAQNLEHFQHNFQDMASVKFPTPLRPLITRDILVETYEESVP
||||||||||| || ||||||||||. || |||.||||||||||||||||||| ||||||||||||| ||  .  ||||||||| .||..||||||||||
VAVKVLHPGLLAQVHMDLLLMKIGSRVLGVLPGIKWLSLPEIVEEFEKLMVQQIDLRYEAQNLEHFQVNFRNVKAVKFPTPLRPFVTREVLVETYEESVP

VSSYQQAGIPTDLKRKIAQLGINMLLKMIFVDNFVHGDLHPGNILVQGADGVSPSLEMQQQQVNVCDTLVATIAPALCPLRLVLLDAGIVAKLQASDLRN
|||||||||| ||||||| ||||||||||||||||| |||||||||||| |.| | | | ||  .|||||.|.  ..|||||||||||||| ||| ||||
VSSYQQAGIPVDLKRKIARLGINMLLKMIFVDNFVHADLHPGNILVQGANGLSSSQEAQLQQADICDTLVVTYPSSICPLRLVLLDAGIVAELQAPDLRN

FRAVFQAVVMGQGHRVAELMLHHAQANECKDVERFKAEMATLVTQARKNIVTLEKLHVSSLLSSVFKLLMTHKVKLESNFASIVVAIMVLEGLGRSLDPT
||||| ||||||| |||||.|||| | ||.||| || ||| |||||||| .||||||||||||||||||||||||||||||||| |||||||||||||| 
FRAVFMAVVMGQGQRVAELILHHARASECRDVEGFKTEMAMLVTQARKNTITLEKLHVSSLLSSVFKLLMTHKVKLESNFASIVFAIMVLEGLGRSLDPK

LDILEAA
|||||||
LDILEAA
Kinase ADCK2.AA ABC1 299-380 29 8.8e-31 108.58 In-house 37-123 (123) Show / Hide 
Range on Protein: 299-380
Range on HMM: 37-123/123
Sequence Identity: 29% (26 aa)

VAVKVLHPGLLSQVSMDLLLMKIGSKALGLLPG---VKWLSLPEIVEEFEKLMVQQTDLRYEAQNLEHFQHNFQ--DMASVKFPTPL
|||||.|||.  |...|...|....|.......   .||..|...|.||.|..... |...||.|.|.....|.  .   ...|...
VAVKVQHPGVREQIHYDINNMEMVVKMCDWFFPGPDFKWFFLMWFVDEFQKELPWECDFNNEARNAEKCRQLFKKFHWPFFYVPRIH
Kinase ADCK2.AA ABC1 299-380 31 1.2e-20 71.65 Pfam 39-126 (126) Show / Hide 
Range on Protein: 299-380
Range on HMM: 39-126/126
Sequence Identity: 31% (28 aa)

VAVKVLHPGLLSQVSMDLLLMKIGSKALGLLPGVK---WLSLPEIVEEFEKLMVQQTDLRYEAQNLEHFQHNFQDM---ASVKFPTPL
|||||.|||. .... |. .|... |.. ...  .   .. | .||.||.| ...  |.| ||.| |.|..|| .      |. |.  
VAVKVQHPGVKKRMMRDIYNMRWMAKWVKRFFPGYRRQRFDLMWIVDEFRKNLPWELDYRREAKNMERFRENFRHWHRQPWVYVPKVY
Kinase ADCK2.AA Ack 283-317 35 0.000252 10.5 In-house 15-50 (266) Show / Hide 
Range on Protein: 283-317
Range on HMM: 15-50/266
Sequence Identity: 35% (13 aa)

VSQAPWHLPKSDHLIPVAVKVLHPGLLSQV--SMDLL
| .. | .| ..| |.||||.| .. ..|   ..|.|
VWRGEWTNPGGKH-IQVAVKCLRSDKMQQPNCMDDFL