Gene ANKRD3 (Mouse)

ANKRD3

Species: Mouse
Alias: Ankrd3, ANKRD3
External Links: MGI , Entrez Gene , Refseq cDNA , Refseq Protein , Phosphosite , iHOP
Annotation:

Classification

Group: TKL
Family: RIPK

Sequence

Name Sequence Type Origin Length Description Download
ANKRD3.kin_dom Protein Kinase Domain Sugen global kinase HMM prediction 264 Kinase domain by global Sugen HMM Fasta, JSON
ANKRD3.NA RNA Sugen 3551 None Fasta, JSON
ANKRD3.AA Protein Sugen 786 None Fasta, JSON

Protein domain

Protein domains of ANKRD3.AA. The domains are annotated by HMM profiles from Pfam and SMART, as well as in-house data which includes HMMs of each individual kinase group, family and subfamily. Here is domain list in details, including sequence identity, significance and alignment. In particular, you can find can find the best hit kinase group/family/subfamily, which is helpful to understand the relationship between kinases.Kinase domain and best hit kinase group/family/subfamily are highlighted in red and blue. Visualized by pviz.

Usage: Zoom in selected region by dragging mouse and zoom out by double-clicking.

Show/hide domain list
Domain Protein name Domain Name Range Identity (%) Significance Score Profile Source Profile Range (length) Alignment
Kinase ANKRD3.AA RIPK 28-283 46 3.4e-161 541.79 In-house 1-290 (290) Show / Hide 
Range on Protein: 28-283
Range on HMM: 1-290/290
Sequence Identity: 46% (134 aa)

VGSGGFGQVYKVRHVHWKTWLAIKCSPSLHVD----DRERMELLEEAKKMEMAKFRYILPVYGICQEP--------VGLVMEYMETGSLEKLLASEP---
||.||||.|.|.||.||..|.|.||.|..|..    |.|||...||||.|.......|.|.||.||..        .|.||||||.|||...|....   
VGGGGFGEVFKARHRHWGDWVAKKCKPCKHCHTHMDDQERMYQKEEAKHMHKLRCEHIVPIYGFCQCEEWDCDCKLYGIVMEYMENGSLWHFLHTKWPYQ

---LPWDLRFRIVHETAVGMNFLHCMSPPLLHLDLKPANILLDAHYHVKISDFGLAKCNGMSHSHD--------LSMDGLF--GTIAYLPPERIR--EKS
   .||.||.|..||...||..||.| ||..|.||||.|||.|...||||.|||||.....||||.        .||....  ||..|.|||..|  .|.
HHPDPWPLRCRMIHEISCGMCYLHSMNPPIIHRDLKPENILVDNNFHVKIADFGLATWMMWSHSHQDRCNQREVYSMKSKNRWGTLSYMPPEHFRTDNKK

RL--FDTKHDVYSFAIVIWGVLTQKKPFADEKNILHIMMKVVKGHRPELPPICRPRPR--ACASLIGLMQRCWHADPQVRPTFQEITSET
..  ...|.||||||||.|.|||||.|..|.|....|||....||||.|.|.....|.  .|...| ||||||..||..||.|||....|
PIKVVTPKYDVYSFAIVMWEVLTQKHPYEDRKCMMMIMMCCKQGHRPCLQPVPEYWPEPPHCEQMIELMQRCWQQDPNDRPCFQECEEWT
Kinase ANKRD3.AA TKL 28-283 27 3e-91 309.46 In-house 1-364 (364) Show / Hide 
Range on Protein: 28-283
Range on HMM: 1-364/364
Sequence Identity: 27% (101 aa)

VGSGGFGQVYKVRHVHWK--------TWLAIKCSPSLHVDDRER-------------------------MELLEEAKKMEMAKFRYILPVYG--------
.||||||.||| ..  |         .. |.|  .| ..| ...                          .. ||.. | . .   |.. .|        
IGSGGFGEVYKGKWRGWGGKCPSDTGKDVAVKKFKSHNDDEFTKNSQENNDNNNYSDMQLNDPEASWFRFFEEEEIMMMSRLRHPNIVQFMGYCCCPPCG

-ICQEP------VGLVMEYMETGS-LEKLLASEPLPWDLRFRIVHETAVGMNFLHCMS------PPLLHLDLKPANILLDAHYH--------------VK
 .| .|       ..||||.. || |. |.      |..|.|.....| |||.|| |       ||..| |||..|||.| ...              .|
CVCMHPVGPWGQLCIVMEYCPGGSLLHYLH------WHQRCRWALDIARGMNYLHSMNPKWCTKPPIIHRDLKSKNILVDENWTNVSNYMYNPNADWCCK

ISDFGLAKCNGMSHSHDLSMDG----------------LFGTIAYLPPERIREK--------------SRLFDTKHDVYSFAIVIWGVLTQKKPFADEKN
|.||||.... .| .   .| .                  ||.....|| .|..              .. ...|.|||||.||.| .|| ..|..|...
ICDFGLSRFMSQSGNMNDTMTTMMESAEHQNNRKTTMTQCGTPRWMAPEVLRGQMNYTEKVGIDEFCKGFEYSEKCDVYSFGIVLWEILTRCRPYYDYPY

ILHI---------MMKVVKGHRPELPPICR------PRPRACASLIGLMQRCWHADPQVRPTFQEITSET
. .|         || ..||.||..|||..      | | .  |.. |||.||..||. ||.||||... 
MPMIFQDPFEEMFMMVCDKGLRPPIPPIWQNHHKMCPCPDCPPSMKKLMQDCWDHDPEKRPSFQEILKRL
Kinase ANKRD3.AA MLK 78-283 29 4.1e-51 175.53 In-house 68-291 (291) Show / Hide 
Range on Protein: 78-283
Range on HMM: 68-291/291
Sequence Identity: 29% (69 aa)

FRYILPVYGICQEP---VGLVMEYMETGSLEKLLASEP---------------LPWDLRFRIVHETAVGMNFLHCMSP-PLLHLDLKPANILLDA-----
. .| ..||.|..|   ...||||.| |||  .|....                . |. ... .  | ||..||.| | |. | |||. |||.|.     
HPCIIQFYGVCLQPPCHFCIVMEYCEGGSLYNVLHGARSKWMDANHNQKNDRVYDHDHAMNWALQCARGMHYLHSMAPKPIIHRDLKSHNILIDEICHDM

-HYHVKISDFGLAKCNGMSHSHDLS-MDGLFGTIAYLPPERIRE-KSRLFDTKHDVYSFAIVIWGVLTQKKPFA-DEKNILHIMMKVVKGHRPELPPICR
 | ..||.|||...   . |... . | .  || |.  || |   ..  .. | ||.|...|.| .|| . |.. . ...  ... ...| || .|. | 
HHGTLKICDFGTSR---DWHQMC-TNMMSNAGTYAWMAPEVIQQFRCEKYSEKCDVWSWGVVLWEMLTREVPYKQHYDPMAIAWWVAYNGLRPPIPSTCP

PRPRACASLIGLMQRCWHADPQVRPTFQEITSET
..      .  ||..||..||  ||.|..| .. 
EH------WKKLMKQCWNQDPHKRPSFRQIVQHL
Kinase ANKRD3.AA TKL-Unique 25-283 28 5.3e-50 172.43 In-house 2-290 (290) Show / Hide 
Range on Protein: 25-283
Range on HMM: 2-290/290
Sequence Identity: 28% (86 aa)

WEKVGSGGFGQVYKVRHVHWKTWLAIKCSPSLHV----DDRERMELLEEAKKMEMAK-FRYILPVYGICQ----EPV--GLVMEYMETGSLEKLLA----
|.|.|.||.|||||.  .. ..  |||   ..|.      ... |. .| . |.. .    |.  .|.|      |    .||||.. ||| ..|.    
WNKIGEGGYGQVYKG--KWRGYPVAIK---QFHPNEDSSNEMMQEFENEVNWMKKLHYHPNIVHYMGYCMDHQVYPPNMCIVMEYCPGGSLYDVLHQNNN

-------SEPLPWDLRFRIVHETAVGMNFLHCMSPPLLHLDLKPANILLDAH-----YHVKISDFGLAKCNGMSHSHDLSMD------GLFGTIAYLPPE
       . .|.. .| ....  | ||..||  .|| .|.|||. |.|.| .     . .||.||||.| |  .    ...       .  |.. ...||
NNNNNNNNCKLNMQQRVKMAIDIAQGMYYLHHCEPPIIHRDLKSSNFLVDNNSNIAEWNIKICDFGLSKFNSKINKMTNNEHKGTRNQTRCGSFRWMAPE

RIREKSRLFDTKHDVYSFAIVIWGVLTQKK------PFADEKNILHIMMKVV--KGHRPELPPICRPRPRACASLIGLMQRCWHADPQVRPTFQEITSET
 .|    ....| |||||.|| |  .| |       |. .   .  . |. .  .. ||..|. | .      ..  |.|.||| ||. ||.|.|| .. 
VLRMNFCQYSEKSDVYSFGIVLWEIATRKITKTYKKPYQGMDQEQWCEMVHYMEENYRPPIPNHCPK------EYRDLIQQCWHHDPSQRPSFDEIIHRL
Kinase ANKRD3.AA Dicty4 95-285 33 2.9e-47 155.75 In-house 80-277 (277) Show / Hide 
Range on Protein: 95-285
Range on HMM: 80-277/277
Sequence Identity: 33% (70 aa)

VMEYMETGSLEKLLAS--------EPLPWDLRFR---IVHETAVGMNFLHCMSPPLLHLDLKPANILLDAHYHVKISDFGLAKCNGMSHSHDLSMDGLFG
|.|||  |.|..|| .         .|.| |. |   .   .| ||| |||  |  .|.|||..|.| |... ||..||||..      .|   ...  |
VTEYMPKGNLYSLLHDKPSEQQQSIKLDWPLIKRAMRMAFDAARGMNWLHCCNPVIIHRDLKSHNLLVDKNWRVKVCDFGLSQYMKKHEDHKDNQMTACG

TIAYLPPERIREKSRLFDTKHDVYSFAIVIWGVLTQKKPFA-DEKNILHIMMKVVK-GHRPELPPICRPRPRACASLIGLMQRCWHADPQVRPTFQEITS
| ..  ||  ....  .. | |||||.|| |  || . |..   ...  .   |.  . ||..|. | |      |.. |.|.||. |||.||.|.||..
TPCWMAPEVMMHQP--YNEKADVYSFGIVLWEILTRQEPYQKHHMPYMQFVRAVCNKKLRPPIPDWCPP------SWKHLIQWCWDHDPQHRPSFEEIIQ

E--TED
.   | 
RRILEH
Pkinase ANKRD3.AA Pkinase 22-279 22 2.4e-45 161.42 Pfam 1-287 (293) Show / Hide 
Range on Protein: 22-279
Range on HMM: 1-287/293
Sequence Identity: 22% (67 aa)

FAGWEKVGSGGFGQVYKVRHVHWKTWLAIKCSPSLHVDDRERMELLE--EAKKMEMAKFRYILPVYGICQ---EPVGLVMEYMETG----SLEKLLA---
.   .|.|||.||.||| .|.      |.|. .  | .. ......   |.. | . .  .|.  |....   ..  .||||.| |    .|  ..    
YHIGRKIGSGSFGCVYKCHHKGTGKIVAVKIIKKRHEKSWKDQTHRRLSEIQIMKRLNHPNIVRLYDWFEDKDHIY-MVMEYCEGGLYVMDLFDYISTWR

SEPL--PWDLRFRIVHETAVGMNFLHCMSPPLLHLDLKPANILLDAHYHV----KISDFGLAKC-NGMSHSHDLSMDGLFGTIAYLPPERIREKSRLFDT
. ..  ...   ... ... |....| |    .| ||||.|||.| ..|.    ||.||||||. .   . ..  |... ||. |..|| || ...  ..
HGCFYFSEWECKFYMYQILRGLEYCHSM--GIIHRDLKPENILIDNNGHIDACVKICDFGLAKQFD---Y-NNS-MTTFCGTPWYMAPEVIR-GGQYYGP

KHDVYSFAIVIWGVLTQKKPFADE-----KNILHIMMKVVKGHRPELPPICRPRP--------------RACASLIGLMQRCWHADPQVRPTFQEI
| |..|. .... .|. . || ..      . .... .. ..  ..  |  ....              ..  ... .. .|.. ||. |||...|
KVDMWSCGCILYEMLCGRPPFPGHCWHDNHDQMQMICRIMGPPLHFDWPWWCSISYFFFRHWHFHWTFHNWSEECKDFIKWCLCKDPKKRPTAEQI
Kinase ANKRD3.AA LRRK 80-285 29 1.6e-44 154.26 In-house 118-351 (351) Show / Hide 
Range on Protein: 80-285
Range on HMM: 118-351/351
Sequence Identity: 29% (71 aa)

YILPVYGICQEPVGLVMEYMETGSLEKLLA---SEP-------LPWDLRFRIVHETAVGMNFLHCMSPPLLHLDLKPANILL---D---------AHYHV
.|.. .|.| .|  .||||.  |.| ..|    . .       ..| |. .|. . | ||..||  .||..| |||. ||||   .         ||...
NIVSLKGFCIHPLCMVMEYAPHGDLYHFLHNKKQDGFHFMKAHISWMLKLKIALQIAKGMEYLHSHNPPIIHRDLKSPNILLWSSPQNHSPNYPNAHVCA

KISDFGLAKCNGMSHSHDLS--MDGLFGTIAYLPPERIREK-SRLFDTKHDVYSFAIVIWGVLTQKKPFADEKN-------ILHIMMKVVKGHRPELPPI
||.|||.     |  . ...    |. |.. .. || .|.     ...| |.|||....|  || . .. || .       . .|  |. .|.|| .|. 
KIADFGISR---MF-QCFHMGVAKGCVGNPGWMAPEIMRYNGEEEYTEKVDCYSFGMILWELLTRQHHPFDEHDFFDHMQWMEQIEDKIIEGLRPTIPQH

-CRP--RPRACASLIGLMQRCWHADPQVRPTFQEITSETED
 |.|   .. . .||   | ||..||. ||.|..|..  ..
YCPPCQPWHMYQDLI---QHCWQHDPKKRPHFSQIVKRLSQ
S_TKc ANKRD3.AA S_TKc 22-281 23 7.9e-41 142.87 SMART 1-220 (231) Show / Hide 
Range on Protein: 22-281
Range on HMM: 1-220/231
Sequence Identity: 23% (63 aa)

FAGWEKVGSGGFGQVYKVRHVHWKTWLAIKCSPSLHVDDRERMELLEEAKKMEMAKFRYILPVYGICQ-EPVGLVMEYMET--GSLEKLLASEP------
.   .|.|.|.||.|||.||.. .   |||. .           .. | . ... .  .|   |...| . . .||||...  |.| ... . .      
YEILRKIGKGAFGKVYKCRHKKTGRIVAIKIIK---------EHIRREIQILKK-HHPNIVKLYDVFQDDHLYMVMEYCDGDLGDLFDYIKKRGRHGLRF

-LPWDLRFRIVHETAVGMNFLHCMSPPLLHLDLKPANILLDAHYHVKISDFGLAKCNGMSHSHDLSMDGLFGTIAYLPPERIREKSRLFDT-KHDVYSFA
 .|     ....... .....| .    .| ||||.|||||   |.||.|||||.            . . ||  |..|| .      ... | |..|. 
PFPE-HARFYMYQICCALEYCHSH--GIIHRDLKPENILLDE--HIKICDFGLARQL----------TTFCGTPWYMAPEVL-----GYGKCKCDWWSCG

IVIWGVLTQKKPFADEKNILHIMMKVVKGHRPELPPICRPRPRACASLIGLMQRCWHADPQVRPTFQEITS
....  |. . ||      .. |.|...                  ... ....|.. ||. |||  |.  
CILYEMLCGYPPFP----QMQMMFKKIG----------------SPEAKDFIRKCLQKDPEKRPTA-EALQ
Kinase ANKRD3.AA TK 26-283 17 3.6e-39 128.42 In-house 5-486 (486) Show / Hide 
Range on Protein: 26-283
Range on HMM: 5-486/486
Sequence Identity: 17% (84 aa)

EKVGSGGFG---QVYKVRHV---HWK----------------------TWLAIKCSPSLH-VDDRERME--------------LLEEAKKME--MAKFRY
.| |.| ||   .||| .      |.                      |  |.|.  . .  ...|...              ..||.|.|   . .   
KKLGEGQFGSFGEVYKGEWRGRNPWNGKRFPCHMTVTLKCKNGKEGGKTPVAVKMLKEGDAMSQEEFFDEEMHDRDGGEDFLEEAEEMKMMCHSLGHHPN

ILPVYGIC--------------QEPVGLVMEYMETGS----LEKLLASEP--------------------------------------------------
|.  ||.|              |||. .|||||. |.    | . | . .                                                  
IVRLYGVCTQGEPKPCFEVVVHQEPWMIVMEYMPHGDMDGSLRDYLRKCRPKFQHEQDCPDNQHNKYPPSKLHHCMKGDITYSHESNSPCPEEQDYDDDL

---------------------------LPWDLRFRIVHETAVGMNFLHCMSP----PLLHLDLKPANILLDAHYH-----------VKISDFGLA-----
                           |.   .  . .  | || .|| .       . | ||   |.|.. ...           .||.||||.     
IKDHPPPLTTKDLLQMAWQWCLTCKHQLTMHQLL-MCWQIACGMEYLHSKNCEFIQNFVHRDLAARNCLVGENNVCKWHFDGCGPVCKIADFGLSRQGSG

-KCNGMSHSHDLSMDGLFGT-------------------------IAYLPPERIREK-------SRLFDTKHDVYSFAIVIWGVLTQK-KPFADEKNI--
  .  . ...|   ..  ||                         | ...|| ....        . | || ||.|| ...| ..|   .|.. . .   
VLARDIYSDDDYYRKSSYGTGRPMWPFEDDPWQDYYRQQSGGKLPIRWMAPECLNDRVFSEAEKYGKFTTKSDVWSFGVLMWEIFTYGQEPYYGGMSNQD

-------LHIMMKVVKG--------------HRPELPPICRP----RPRACA-----SLI-GLMQRCWHADPQVRPTFQEITSET
         .| ....|              .|.. || | .    |  .        ..  |||.|||.||. ||||... .. 
VWKDGDNQEVMEYLRRGGRLCRSGLNEVGYRMRMPQPPHCPDWMRYRM-H-PPHCPPEEYYDLMQQCWHYDPEDRPTFSQLHEQL
Kinase ANKRD3.AA DRK 95-285 36 7.7e-34 112.01 In-house 75-258 (258) Show / Hide 
Range on Protein: 95-285
Range on HMM: 75-258/258
Sequence Identity: 36% (71 aa)

VMEYMETGSLEKLLASE--PLPWDLRFRIVHETAVGMNFLHCMSPPLLHLDLKPANILLDAHYHVKISDFGLAKCNGMSHSHDLSMDGLFGTIAYLPPER
.||||  ||| . |  |   . | |. ..    | ||..|||  |  .| |||  | | | |. ||..||||.       .|   |    ||     || 
CMEYMPRGSLYNILHDESIEMDWPLMKQMMFDCAKGMIYLHCCNPIIIHRDLKSHNLLVDEHWQVKVADFGLSTRFKKHKQHKFAM-TMCGTPCWTAPEV

IREKSRLFDTKHDVYSFAIVIWGVLTQKKPFADEKNILHIMMKVVK-GHRPELPPICRPRPRACASLIGLMQRCWHADPQVRPTFQEITSETED
 |.    .  | |||||||| | ..| . |..  .. . . . | . | ||  |. | |        | ||..||  ||| ||..||.    | 
LRNQR--YTEKADVYSFAIVLWECVTRQDPYFG-MPTFQVVFSVGRHGMRPPMPQWCPPK------YIQLMNDCWNEDPQHRPSMQECLERLEA
Kinase ANKRD3.AA TKL-ciliate1 94-279 27 2e-30 101.32 In-house 76-275 (279) Show / Hide 
Range on Protein: 94-279
Range on HMM: 76-275/279
Sequence Identity: 27% (56 aa)

LVMEYMETGSLEKLLA---S--EPLPWDLRFRIVHETAVGMNFLHCMSPPLLHLDLKPANILLDAHYHVKISDFGLAKCNGMSHSHDLSMDGL------F
..||. . |..  ..    |   ...|. | |.. . | || .||   .|| | |||  |||.|  |  || .|.  | .        | . .       
IIMEHCHKGTMFDICHRKHSQIYMIKWQHRMRWCKDIAQGMQYLHMRQNPLIHRDLKMQNILYDEPYQYKICNFPHVKIADFHRIRNCSFQDMQNEMQRN

GTIAYLPPERIR---EKSRLFDTKHDVYSFAIVIWGVLTQKKPFADEKNILHIMMKVVKGH-RPELPPICRPRPRACASLIGLMQRCWHADPQVRPTFQE
.|  .  || ..      .   .| |.|...|| .     |.||    . . ||  .  .  || | |   .     .... ||.|||  .|  || |.|
TTFHWMAPEQMDPHIFPNYPINEKIDIYAYGIVMYILCFRKTPFQQKMSVINIMCYWCEFPGRPNLGPQFIHF-DCPQNFHNLMMRCWCQNPNKRPNFNE

I
|
I
Kinase ANKRD3.AA TyrKc 26-286 27 3.4e-29 104.23 SMART 5-280 (280) Show / Hide 
Range on Protein: 26-286
Range on HMM: 5-280/280
Sequence Identity: 27% (80 aa)

EKVGSGGFGQVYKVRHVHWKTWLAIKCSPSLHVDDRERMELLEEAKKMEMA--KFRYILPVYGICQ---------EPVGLVMEYMETGSLEKLLASEP--
.| |.| ||.||| .     .  |.|.  . .     |.....||. | .   .   |.  ||.|          ||. .|||||. |.| . | .    
KKLGEGAFGEVYKGTWK---IQVAVKMLKEDA-----REDFMREARIMCKLGGHHPNIVRLYGVCTQQGRNFMYIEPLMIVMEYMPHGDLKDYLRKHRPK

LPWDLRFRIVHETAVGMNFLHCMSPPLLHLDLKPANILLDAHYHVKISDFGLAKCNGMS------HSHDLSMD--GLF--GTIAYLPPERIREKSRLFDT
|...    . .  | ||..|| .  .. | ||   |.|... ..||||||||..  .        ..   ..   |      |  ..|| |  . . | |
LCMKDLLSFCWQIACGMEYLHSK--NCIHRDLAARNCLVGENHTVKISDFGLSRDIYDDDQQGESKDYYRKKEHKGGKTMLPIRWMAPECI--NYGKFTT

KHDVYSFAIVIWGVLTQ-KKPFADE----KNILHIMMKVVKGHRPELPPI-----CRPRPRACASLIGLMQRCWHADPQVRPTFQEITSETEDL
| ||.|| ...| ..|  ..|  ..    ..  ... .| .|.|.. ||          ... . .  .|..|||.||  ||||.||    |..
KSDVWSFGVCMWEIFTYGQQPYPGMIQQMMSNQEVIEYVKQGYRMPQPPNDYPMSF---VCCPDEMYQIMKQCWHEDPEDRPTFSEI---HECF
Kinase ANKRD3.AA Pkinase_Tyr 26-286 29 7e-24 81.5 Pfam 5-270 (270) Show / Hide 
Range on Protein: 26-286
Range on HMM: 5-270/270
Sequence Identity: 29% (84 aa)

EKVGSGGFGQVYKVRHV----HWKTWLAIKCSPSLHVDDRE--RMELLEEAKKMEMA-KFRYILPVYGICQ---EP--VGLVMEYMETGSLEKLLASE--
.| |.| ||.||| .        |.  |.|. .  . ....  | ....||| |    .   |.  ||.|    ||  . .|||||. |.| . | .   
KKLGEGAFGEVYKGTWKGDPDNTKIPVAVKMLKE-GAMHEQNCREDFMREAKIMKQLGHHPNIVRLYGVCTDQGEPNQIYIVMEYMPHGDLLDYLRKHRE

---PLPWDLRFRIVHETAVGMNFLHCMSPPLLHLDLKPANILLDAHYHVKISDFGLAKCNGMSHSHD-LSMDGLFGTIAYLPPERIREKSRLFDTKHDVY
   ||.      . .. | ||..|. .   . | ||   |.|..   .|||.|||||.   .. .    . .|    |  ..|| |...   | || ||.
DKQPLTMKDLLQMCWQIAKGMEYLESKN--CIHRDLAARNCLVTENNVVKICDFGLARDI-YNDDYYYRKRGGGKLPIKWMAPECINYGK--FTTKSDVW

SFAIVIWGVLT-QKKP-FADEKNILHIMMKV-VKGHRPELPPICRPRPRACASLIGLMQRCWHADPQVRPTFQEITSETEDL
|| ...| ..|  ..| ... .|   .. ..  .|.| . |. |      .. .  ||..|||.||. ||||.||    |.|
SFGVLMWEIFTYGEQPTYPGMSNEE-VYEYIYEDGYRMPCPENC------PDEIYDLMKQCWHYDPEDRPTFSEI---HEQL
Kinase ANKRD3.AA TAK1 201-282 28 9.4e-19 59.89 In-house 203-284 (284) Show / Hide 
Range on Protein: 201-282
Range on HMM: 203-284/284
Sequence Identity: 28% (24 aa)

DTKHDVYSFAIVIWGVLTQKKPFADEKN---ILHIMMKVVKGHRPELPPICRPRPRACASLIGLMQRCWHADPQVRPTFQEITSE
. | |.||..|. | |.. |.|. .  |   .  ||... .|   ..||  . |  .   .  .|..||  .|  ||. ||.   
NMKCDIYSWGIIMWEVISRKHPYDHIMNPNSAYRIMWAIHNG---NRPPMETNRSDCPKRIEQFMKCCWDDNPEKRPSMQECVKY
Kinase ANKRD3.AA TAK1 81-165 36 8e-15 46.41 In-house 60-153 (284) Show / Hide 
Range on Protein: 81-165
Range on HMM: 60-153/284
Sequence Identity: 36% (34 aa)

ILPVYGI--CQE-PVGLVMEYMETGSLEKLLAS-EPLP---WDLRFRIVHETAVGMNFLHCMS-PPLLHLDLKPANILLDAHYHV-KISDFGLA
|  .||.  | . ...||||||. |||  .| . .| .    .  ..  |  | | ..|| |.  |. | |.||.| || ... . || |||..
IIKLYGMYACHRQCQCLVMEYMDCGSLHNFLHGAKPKWEYTHAHAMSWMHQCAQGVAYLHSMQPKPQIHRDIKPQNMLLCNKHRTLKICDFGTF
Kinase ANKRD3.AA MLK 22-40 47 0.026895 3.93 In-house 1-19 (291) Show / Hide 
Range on Protein: 22-40
Range on HMM: 1-19/291
Sequence Identity: 47% (9 aa)

FAGWEKVGSGGFGQVYKVR
.   |..|||.||.|.| |
IQFHEWIGSGSFGKVWKGR
Kinase ANKRD3.AA LRRK 22-38 44 0.031626 3.66 In-house 1-18 (351) Show / Hide 
Range on Protein: 22-38
Range on HMM: 1-18/351
Sequence Identity: 44% (8 aa)

FAGWEKVGSGGFG-QVYK
.   |..|.||||  ||.
LKIEEQIGRGGFGTFVYR
Kinase ANKRD3.AA Dicty4 22-38 41 0.192694 0.77 In-house 1-17 (277) Show / Hide 
Range on Protein: 22-38
Range on HMM: 1-17/277
Sequence Identity: 41% (7 aa)

FAGWEKVGSGGFGQVYK
 .  .. |.|.||.|||
INIEQRIGKGSFGEVYK
Ank ANKRD3.AA Ank 605-637 45 6.1e-10 40.11 Pfam 1-33 (33) Show / Hide 
Range on Protein: 605-637
Range on HMM: 1-33/33
Sequence Identity: 45% (15 aa)

DGRTPLHLAAQRGHYRVARILIDLCSDVNICSL
||.||||||...||..|.. |..   |||.   
DGFTPLHLACRCGHTEVVKMLLQHGADVNAQDD
Ank ANKRD3.AA Ank 671-703 45 2.6e-09 37.82 Pfam 1-33 (33) Show / Hide 
Range on Protein: 671-703
Range on HMM: 1-33/33
Sequence Identity: 45% (15 aa)

EGYTALHLAAQNGHLATVKLLIEEKADVMARGP
.|.|.||||...||.  ||.|..  ||| |.  
DGFTPLHLACRCGHTEVVKMLLQHGADVNAQDD
Ank ANKRD3.AA Ank 538-570 42 1.4e-08 35.16 Pfam 1-33 (33) Show / Hide 
Range on Protein: 538-570
Range on HMM: 1-33/33
Sequence Identity: 42% (14 aa)

EGRTPMHVACQHGQENIVRTLLRRGVDVGLQGK
.|.|| |.||..|....|. || .| || .| .
DGFTPLHLACRCGHTEVVKMLLQHGADVNAQDD
Ank ANKRD3.AA Ank 472-504 39 3.9e-08 33.6 Pfam 1-33 (33) Show / Hide 
Range on Protein: 472-504
Range on HMM: 1-33/33
Sequence Identity: 39% (13 aa)

KGSTPLHMAVERKGRGIVELLLARKTSVNAKDE
 | ||||.|... .  .|..|| .  .|||.| 
DGFTPLHLACRCGHTEVVKMLLQHGADVNAQDD
Ank ANKRD3.AA Ank 505-537 36 1.6e-07 31.39 Pfam 1-33 (33) Show / Hide 
Range on Protein: 505-537
Range on HMM: 1-33/33
Sequence Identity: 36% (12 aa)

DQWTALHFAAQNGDEASTRLLLEKNASVNEVDF
| .|.|| |...|..   ..||...|.|| .| 
DGFTPLHLACRCGHTEVVKMLLQHGADVNAQDD
Ank ANKRD3.AA Ank 704-734 42 3e-06 26.59 Pfam 1-33 (33) Show / Hide 
Range on Protein: 704-734
Range on HMM: 1-33/33
Sequence Identity: 42% (14 aa)

LNQTALHLAAARGHSEVVEELVS--ADLIDLSD
  .|.||||. .|| |||..|..  ||.    |
DGFTPLHLACRCGHTEVVKMLLQHGADVNAQDD
Ank ANKRD3.AA Ank 571-604 44 5e-06 26.07 Pfam 1-33 (33) Show / Hide 
Range on Protein: 571-604
Range on HMM: 1-33/33
Sequence Identity: 44% (15 aa)

DAWLPLHYAAWQGHLPIVKLLAKQPGVSVNAQTL
| . |||.|.  ||. .||.| .  | .||||. 
DGFTPLHLACRCGHTEVVKMLLQ-HGADVNAQDD
Ank ANKRD3.AA Ank 638-670 39 6e-06 25.68 Pfam 1-33 (33) Show / Hide 
Range on Protein: 638-670
Range on HMM: 1-33/33
Sequence Identity: 39% (13 aa)

QAQTPLHVAAETGHTSTARLLLHRGAGKEALTS
  .||||.|.. |||. ...|| .||   | . 
DGFTPLHLACRCGHTEVVKMLLQHGADVNAQDD
Ank ANKRD3.AA Ank 444-471 42 9e-06 25.02 Pfam 6-33 (33) Show / Hide 
Range on Protein: 444-471
Range on HMM: 6-33/33
Sequence Identity: 42% (12 aa)

LHLAVEAGQEECVKWLLLNNANPNLTNR
||||.. |..|.||.|| ..|..|....
LHLACRCGHTEVVKMLLQHGADVNAQDD
Ank ANKRD3.AA Ank 736-768 42 1.8e-07 31.17 Pfam 1-33 (33) Show / Hide 
Range on Protein: 736-768
Range on HMM: 1-33/33
Sequence Identity: 42% (14 aa)

QGLSALHLAAQGRHSQTVETLLKHGAHINLQSL
 | ..||||..  | . |. ||.||| .|.|  
DGFTPLHLACRCGHTEVVKMLLQHGADVNAQDD