Gene AurC (Mouse)

AurC

Species: Mouse
Alias: AurC
External Links: Entrez Gene , Refseq cDNA , Refseq Protein , Phosphosite , iHOP
Annotation:

Classification

Group: Other
Family: Aur

Sequence

Name Sequence Type Origin Length Description Download
AurC.kin_dom Protein Kinase Domain Sugen global kinase HMM prediction 251 Kinase domain by global Sugen HMM Fasta, JSON
AurC.NA RNA Sugen 1168 None Fasta, JSON
AurC.AA Protein Sugen 315 None Fasta, JSON

Protein domain

Protein domains of AurC.AA. The domains are annotated by HMM profiles from Pfam and SMART, as well as in-house data which includes HMMs of each individual kinase group, family and subfamily. Here is domain list in details, including sequence identity, significance and alignment. In particular, you can find can find the best hit kinase group/family/subfamily, which is helpful to understand the relationship between kinases.Kinase domain and best hit kinase group/family/subfamily are highlighted in red and blue. Visualized by pviz.

Usage: Zoom in selected region by dragging mouse and zoom out by double-clicking.

Show/hide domain list
Domain Protein name Domain Name Range Identity (%) Significance Score Profile Source Profile Range (length) Alignment
Kinase AurC.AA Aur 55-305 59 9.5e-234 624.67 In-house 1-257 (257) Show / Hide 
Range on Protein: 55-305
Range on HMM: 1-257/257
Sequence Identity: 59% (154 aa)

FEIGRPLGRGKFGRVYLARLKENHFIVALKVLFKSEIEKEGLEHQLRREVEIQAHLQHRNILRLYNYFYDDTRIYLILEYAPGGELYKELQRH--QKLDQ
||||.|||.||||.||||| |. |||.||||.||..|.|...|||||||..|| ||.| |||..|.||.||.|||||||||||||||||||..  ...| 
FEIGKPLGKGKFGNVYLARHKKTHFIFALKVMFKEQIKKYCMEHQLRREIKIQSHLNHPNILKMYGYFHDDQRIYLILEYAPGGELYKELQKQPNKRFDE

QRTATIIQELSDALTYCHEKKVIHRDIKPENLLLG-LNGEVKISDFGWSVHTP-SLRRKTMCGTLDYLPPEMIAQKPYNEMVDLWCIGVLCYELLVGKPP
||.|...... .||.|||.|..|||||||||.||. .||..||.|||||||.| . ||.|.||||||.||||.  ......||.||.|||||||..|.||
QRAAKYMYQICNALDYCHSKNIIHRDIKPENILLDQCNGNIKICDFGWSVHCPNNNRRMTFCGTLDYMPPEMVEGQMHDHKVDIWCLGVLCYELCHGCPP

FES-STSSETYRRIR-QVDFKFPSSVPAGAQDLISKLLRYHPSERLSLAQVLKHPWV
||| .. .|||.||. .||..|||... .|.|||||.|.. |..|..|.|...|||.
FESNENHDETYDRIKNKVDIQFPSHISKEAKDLISKILQHDPKQRMTLDQIMNHPWI
Kinase AurC.AA AGC 55-305 23 1.1e-107 278.92 In-house 1-395 (395) Show / Hide 
Range on Protein: 55-305
Range on HMM: 1-395/395
Sequence Identity: 23% (95 aa)

FEIGRPLGRGKFGRVYLARLKENH------FIVALKVLFKSE---IEKEGLEHQLRRE------------VEIQAHLQ----------HRNILR-LYNYF
||. ...|.| ||.|||.| |...       . |.||| |..   | |.  ...  .|             .| ....          | .| . |.  |
FEFLKVIGKGSFGKVYLVRKKDGCHKKDTGKYYAMKVLKKKHKIVIKKKNMVEHTMTEHWKQDQGYVWEERNILEKCNHTHNHPIKSHHPFIVKILHYSF

YDDTR--IYLILEYAP---------GG-ELYKELQ---RHQKLDQQRTATIIQE-------LSDALTYCHE-KKVIHRD-IKPENLLLGLNGEVKISDFG
 |...  .|...||.|         || ||.  ||   . ...| .|.  .. |       .  || | |. ...|||| .||||.||  .| .|..|||
QDKDHTYLYFVMEYMPRYVNDLYCGGGCELFLHLQGRRKEGRFDEERARFYAAEMQKICGCIVLALEYLHSHMGIIHRDYLKPENILLDEDGHIKLTDFG

WSVHTPSL----------------------------------------------------RRKTMCG--TLDYLPPEMIAQKPYNEMVDLWC--IGVLCY
 .   ..                                                     | .|.||  | .|..||..    |.  .| |.   |.| |
LCKEGMNDGEKGQQSQSNMKFHWHNKKYQKSNMDTNKCNPNNWQRNNMSQEDDTTRKKRDRTWTFCGPCTPEYMAPEIL----YGKACDWWSFGLGCLMY

ELLVGKPPFESSTSS----------ETYRRIR------QVDFKFP----------SSVPAGAQDLISKLLRYHPSERLS----------LAQVLKHPWV
|.|.|.||| . .            |.. .|.      . . |||          ...   |.|||.|||  .|..||             .. .||| 
EMLTGYPPFYGDNPQENRHPFRNPMEMFQKIMNGRYFINWKVKFPFPEDPQFPEDRWFSPEAKDLIKKLLCKDPEKRLGCGGNDFGDKGAEEIKNHPWF
Kinase AurC.AA S_TKc 55-305 30 8.3e-98 332.15 SMART 1-231 (231) Show / Hide 
Range on Protein: 55-305
Range on HMM: 1-231/231
Sequence Identity: 30% (82 aa)

FEIGRPLGRGKFGRVYLARLKENHFIVALKVLFKSEIEKEGLEHQLRREVEIQAHLQHRNILRLYNYFYDDTRIYLILEYAPG--GELYKELQRHQK---
.||.|..|.| ||.||..| |. . |||.|..            ..|||..|  . .| || .|| .|.| ...|...||..|  |.|.. ......   
YEILRKIGKGAFGKVYKCRHKKTGRIVAIKIIK----------EHIRREIQILKK-HHPNIVKLYDVFQD-DHLYMVMEYCDGDLGDLFDYIKKRGRHGL

---LDQQRTATIIQELSDALTYCHEKKVIHRDIKPENLLLGLNGEVKISDFGWSVHTPSLRRKTMCGTLDYLPPEMIAQKPYNE-MVDLWCIGVLCYELL
   ..  ... ..... .|| |||....||||.||||.||    ..||.||| . .      .|.|||..|..||..   .|.   .| | .|.. ||.|
RFPFPE-HARFYMYQICCALEYCHSHGIIHRDLKPENILLDE--HIKICDFGLARQL-----TTFCGTPWYMAPEVL---GYGKCKCDWWSCGCILYEML

VGKPPFESSTSSETYRRIRQVDFKFPSSVPAGAQDLISKLLRYHPSERLSLAQVLK-------HPWV
.|.|||.  .  .....|.          .  | |.|.|.|.. |..|..  ..|.       |||.
CGYPPFP--QMQMMFKKIG----------SPEAKDFIRKCLQKDPEKRPTA-EALQDEWDIKCHPWF
Kinase AurC.AA CAMK 60-305 21 5.9e-95 306.4 In-house 1-425 (425) Show / Hide 
Range on Protein: 60-305
Range on HMM: 1-425/425
Sequence Identity: 21% (90 aa)

PLGRGKFGRVYLARLKENH------------FIVALKVLFKSEIEK-------------------------EGLEHQLRREVEIQAHLQ-------HRNI
 |||| || |.|.. |..               || |.. |. . .                         .  ....|||.||  .||       |.||
TLGRGSFGKVKLCIHKNTTGKERVHHIYTNGQKVAIKIIDKKKLKDKQNQDYSNCYKIDKSKCKHRYCWRRPKDRKNVRREIEIMKKLQGIGNKLDHPNI

LRLYNYFYD-------------------DTRIYLIL---EYAPGGEL----YKELQRH---------------QKLDQQRTATIIQELSDALTYCHEKKV
..|| .. |                   |...|...   ||..||||    .  ...|                ... . ...... . .|. |||....
IKLYEVYEDPHYFKNTNDYETSKQVFTKDKHMYMVMEIMEYCSGGELFDDLFDYIVEHGCYGEEFDQFDIVERGRFTEREARRYFRQICSAVHYCHSHNI

IHRDIKPENLLLGLN-----------------GEVKISDFGWSVHTPSLR-------------------------RKTMCGTLDYLP-PEMIAQ------
.|||.||||.||  |                 . .||.||| . . ..                            ||.|||. | . ||.. .      
VHRDLKPENILLDDNNDDSDPVEHDEIFDWNNNNIKIIDFGFANKFDPGENNFMCSDYKGGEMHNQWTTPTEGQKMKTFCGTPEYMAAPEVLNGKGHCNM

--------KPYNEMVDLWCIGVLCYELLVGKPPFESS-------------TSSETYRRIRQVDFKFPSS------------------------VPAGAQD
        ..|.. .| | .||..| .|.|.|||...             . .|....|.. .. ||..                        | . ..|
QNATDEEKPYYGPKCDMWSCGVILYIMLCGYPPFYGDCDNEICEDEWIGMNDYELFEKIMKGKYDFPPPYFSPISCNYGPEWWDDISDEFHHFVSQECKD

LISKLLRYHPSERLSLAQVLKHPWV
||.|.|.. |..|....|.|.|||.
LIRKMLQVDPEKRMTIEQCLNHPWM
Kinase AurC.AA Pkinase 55-305 30 1.5e-88 305.27 Pfam 1-293 (293) Show / Hide 
Range on Protein: 55-305
Range on HMM: 1-293/293
Sequence Identity: 30% (89 aa)

FEIGRPLGRGKFGRVYLARLKENHFIVALKVLFKSEIEKEGLEHQLR-REVEIQAHLQHRNILRLYNYFYDDTRIYLILEYAPGG----ELYKELQ--RH
..|||..|.| ||.||... | .  |||.|.. |...... ... .| .|..| ..|.| ||.||| .|.|...||...||..||    .|.  ..  ||
YHIGRKIGSGSFGCVYKCHHKGTGKIVAVKIIKKRHEKSWKDQTHRRLSEIQIMKRLNHPNIVRLYDWFEDKDHIYMVMEYCEGGLYVMDLFDYISTWRH

QKL--DQQRTATIIQELSDALTYCHEKKVIHRDIKPENLLLGLNGEV----KISDFGWSV---HTPSLRRKTMCGTLDYLPPEMIA-QKPYNEMVDLWCI
 ..  . .    .. ..  .| |||....||||.||||.|.  ||..    ||.||| .    . ..   .| |||..|..|| |  ...|   || | .
GCFYFSEWECKFYMYQILRGLEYCHSMGIIHRDLKPENILIDNNGHIDACVKICDFGLAKQFDY-NNS-MTTFCGTPWYMAPEVIRGGQYYGPKVDMWSC

GVLCYELLVGKPPFESS------TSSETYRRIRQVDFKFPSSVP---------------------AGAQDLISKLLRYHPSERLSLAQVLKHPWV
|...||.| |.||| ..      .  . ..||.. ...|... .                       ..|.|...|.. |..|.. .|.|.|||.
GCILYEMLCGRPPFPGHCWHDNHDQMQMICRIMGPPLHFDWPWWCSISYFFFRHWHFHWTFHNWSEECKDFIKWCLCKDPKKRPTAEQILQHPWF
Kinase AurC.AA CAMKL 55-305 31 4.5e-88 281.14 In-house 1-297 (297) Show / Hide 
Range on Protein: 55-305
Range on HMM: 1-297/297
Sequence Identity: 31% (93 aa)

FEIGRPLGRGKFGRVYLARL-KENHFIVALKVLFKSEIEKEGLEHQ------------LRREVEIQAHLQ---HRNILRLYNYFYDDTR------IYLIL
..||. ||.| || | ||.  . .   || |.. |. | ..   ..            .|||..|. .|.   | || .||  .....       |||..
YRIGKTLGKGSFGKVKLATHIRTTGEKVAIKIIDKKKIWNDPWMKKNKCGQKHESDMRIRREIQIMKMLNIGKHPNIIKLYEVIETPEHDIETKKIYLVM

EYAPGGE--LYKELQRH----QKLDQQRTATIIQELSDALTYCHEKKVIHRDIKPENLLLGLNG--EVKISDFGWSVH-TP-----SLRRKTMCGTLDYL
||..|||  |.  ...|    ....   .  . . . .|. |||.....||||||||.||  ||   .||.||| | . .|         || ||.. | 
EYCSGGEMDLFDYIVKHGHRRGRMPEHEARRYFRQIVSAVNYCHSHGIVHRDIKPENILLDENGNNNIKIIDFGFSNMYRPCIFGPGQKLKTFCGSPPYM

PPEMIAQ--KPYN-EMVDLWCIGVLCYELLVGKPPFESSTSS-------ETYRRIRQVDFKFP--SSVPAGAQDLISKLLRYHPSERLSLAQVLKHPWV
.||...   |||.   || | .||. | ...|. ||.  | .       . |..|..  ...|  ..|.  ..|||.|.|   |..| .. |...|||.
APEIFQGNNKPYDGPKVDIWSCGVILYAMVCGYLPFDDDTYNKQGKDNIYLYWKIMCG-YYPPIWYHVS-DCRDLIRKMLQVNPEKRPTIHQIMNHPWM
Kinase AurC.AA Ciliate-E2a 55-305 31 4.8e-83 244.3 In-house 1-275 (275) Show / Hide 
Range on Protein: 55-305
Range on HMM: 1-275/275
Sequence Identity: 31% (86 aa)

FEIGRPLGRGKFGRVYLARLKENHFI-VALKVLFKSEIEKEGLEHQLRREVEIQAHLQHRNILRLYNYFYDDTRIYLILEYAPGGELYKELQRHQKLDQQ
... . .| |.||.||||..|.. .  .. |.  | ...|.| | .. .|. |   | | ||..|| .. |.. .||..||  |||||.... ...... 
YKFIKKIGKGNFGSVYLAQHKQTGKQFAMKKFIKKMYQQKKGKE-YFMNEINIMRQLDHPNIIKLYEVYEDENNYYLVMEYCEGGELYDKIKQCKRFFEE

--RTATIIQELS-DALTYCHEKKVIHRDIKPENLLLG---LNG----EVKISDFGWSVHT-PSL--RRKTMCGTLDYLPPEMIAQKP------YNEMVDL
    . |.| |  ..| |.| ....|||.||||.|.     |.    ..||.||| .    .    .....|||  |..|| .. |       | . .|.
IQEICDIMQQLLWQGLHYMHQRNIMHRDLKPENILFKNCSKNSIQNSDIKIIDFGLATFIDKDEKKYMFQKCGTPGYVAPEVLNNKEVLKHKQYDTKCDM

WCIGVLCYELLVGKPPFESSTSSETYRRIRQVDFKFPSSV-----PAGAQDLISKLLRYHPSERLSLAQVLKHPWV
| .||  | ||.|||||.  | .|.   ...  . | ...     .  ..||..|.| . |..|.. .| |.|||.
WSCGVIFYILLCGKPPFKGKTYNEILQQNKKCKIDFNCPECWEKCSKECKDLMKKMLEKDPKKRITAQQALNHPWF
Kinase AurC.AA Ciliate-E2 55-305 24 9.9e-81 274.51 In-house 1-365 (365) Show / Hide 
Range on Protein: 55-305
Range on HMM: 1-365/365
Sequence Identity: 24% (91 aa)

FEIGRPLGRGKFGRVYLARLKEN-----------------------HFIVALKVLFKSEIEKEGLEHQLRREVE----------IQAHLQHRNILRLYNY
... . .|.| || ||... ...                        .|.|.|.. |..||    | .. ||..          |. .|.| ||...| .
YKFIKKIGQGNFGSVYKCKVWKVQKQFAIKIIDQKQQRQQMQEKVKIKIYAMKIMKKNQIEQIKQEIHIMREINCFYKKINEKNILEQLNHPNIIKMYEC

FY--DDTRIYLILEYAPGGELYK-----ELQRHQK------LDQQRTATIIQELSD---------------ALTYCHEKK-VIHRDIKPENLLLGLNGEV
|.  ||. |||..||. ||.|..      ..|...      .. .  ..|.... .               || |.|.|. .|||||||||.|.     .
FQEKDDNNIYLVMEYCQGGDLFDYIKNNKKKRNHEIEKDKYFTEKEIKYIMKQILQGFKTKAEFYIACIILALEYLHSKNNIIHRDIKPENILF-----I

KISDFGW--SVHTP-------SLRR------------------------KTMCGTLDYLPPEMIAQKP---------YNEMVDLWCIGVLCYELLVGKPP
||.|||    ....       ...                         .| |||. |..||..  |.         |....|.|..||. ||.| ||||
KIIDFGLSKKYDDDNQNRTHKQQCKWYMFKNDTSRTPGYMDQIIQQNMFNTICGTPGYMAPEILNGKKYDNQQKQKGYDYKCDIWSLGVILYEMLFGKPP

FESSTSSETYRRIRQVDFKFP------------------SSVPAGAQDLISK----LLRYHPSERLS-LAQVLKHPWV
|        .. | | ...||                   ...  ..|||.|    .| . |..|..   |.|.||| 
F--------QQQIKQCKIDFPCPEWQKDTQCIQCKWKSWKKWSQECKDLIKKFGKRMLQKDPEKRITGWEQILNHPWF
Kinase AurC.AA MARK 55-305 35 1.1e-78 256.88 In-house 1-262 (262) Show / Hide 
Range on Protein: 55-305
Range on HMM: 1-262/262
Sequence Identity: 35% (93 aa)

FEIGRPLGRGKFGRVYLARLKENHFIVALKVLFKSEIEKEGLEHQLRREVEIQAHLQHRNILRLYNYFY--DDTR-IYLILEYAPGGELYKELQRH--QK
..... .| | .. |.||. |  .  ||.|.. |  . .      ..||.||  .|.| || .|. ..   . .. ||||.|||.|||||  .. |   .
YKMLKTIGHGSYAKVKLACHKHTGRKVAIKIYEKFKLNDPQWMKNVMREIEIMKKLDHPNIIKLFHVIEQDTEQHQIYLIMEYASGGELYDYIKAHPNGR

LDQQRTATIIQELSDALTYCHEKKVIHRDIKPENLLLGLNG--EVKISDFGWSVHTPSLR-RKTMCGTLDYLPPEMIAQKPYN-EMVDLWCIGVLCYELL
|    . .| . .  |. |||.| ..||||||||.|.  ||   .||.|||.|.. |. .  .| |||. | .||.. .|||.   || |  ||. | ..
LHEEEARRIFRQIVSAVNYCHSKNIVHRDIKPENILIDENGNHNIKIIDFGFSICIPPGQKLNTFCGTPPYMAPEIFLKKPYDGPKVDIWSLGVVLYFMV

VGKPPFESST--SSETYRRIRQVDFKFPSSVPAGAQDLISKLLRYHPSERLSLAQVLKHPWV
.|. ||. .|    | |..|.  ....|. |......||..||   |.|| .. ...||||.
CGYFPFDGDTQDYKELYKKILRGKYDIPCHVSKECRNLIQRLLTVNPEERPTIEEIMKHPWM
Kinase AurC.AA CAMK-Unique 55-305 22 1.7e-75 248.61 In-house 1-363 (363) Show / Hide 
Range on Protein: 55-305
Range on HMM: 1-363/363
Sequence Identity: 22% (81 aa)

FEIGRPLGRGKFGRVYLARLKENHFIVALKVLFK----SEIEKE-------------GLEHQLRREVEIQAHLQHRNILRLYNY----FYDDT-------
 . .|..| | || || .  .|.  . | |.. |    ... |.              .. .|.||..|   . | ||..|| .    | |..       
YKMHRIIGHGNFGHVYECMDRETGKKWACKMVKKQTHGNKKQKQQRNFDLRYKITEKRRDMKLKREHQIWKMVDHPNIIKLYDWNNPIFCDRKYPLCDLI

--------RIYLILEYAPGGELYKELQR--------------------HQKLDQ--QRTATIIQELSDALTYCHEKKVIHRDIKPENLLLGLNGE-----
        ..|...||..||.|....|.                     ...      |..|.|.|  |. | |.....|||.|.||...  ..      
IKTPRALPYMYIVMEYCQGGDLFDWIQKWDEFYFNFIIKFDFNILKRCQGHFSERCWDTCFIMQCLLSAVAYMHSQDIVHRDLKLENIMVCYSFKDNNHH

-----------VKISDFGWSVHTPSLRRK----TMCGTLDYLPP--------------EMIAQKPYNEMV----DLWCIGVLCYELLVGKPPFESSTSS-
           .|..||| ..|  . .      |||||..|. |              |.|.. .| . .    |.| .||. |..|.|.|||.....  
RDFPYDWSNWHIKLCDFGLCCHYNHNKMCHMMQTMCGTPCYMAPEIVFCKNYQEMTRDEVINMQCYDQQCSPASDIWSLGVIMYYMLCGCPPFDCECEDR

-------ETYRRIRQVDF-KFPSSVPAG-------AQDLISKLLRYHPSERLSLAQVLKHPWV
       |....|.. |. .|....  |       | |.. ... . |. |.|... |.|.|.
DYENHDKEIFECICKGDYCNFDWKMWHGPDYISQEAKDFVKCCMTVDPDHRWSAKELLEHQWI
Kinase AurC.AA PLK 55-305 34 2e-75 245.12 In-house 1-258 (258) Show / Hide 
Range on Protein: 55-305
Range on HMM: 1-258/258
Sequence Identity: 34% (90 aa)

FEIGRPLGRGKFGRVYLARLKENHFIVALKVLFKSEIEKEGLEHQLRREVEIQAHLQHRNILRLYNYFYDDTRIYLILEYAPGGELYKELQRH-QKLDQQ
.|.|..||.| | ..| ..  ... ..| ||  || ..|...   ...|.||.  |.|.||......| |.  .|. |||.....|   . |.  .|   
YERGHFLGKGGFAKCYEMTDIHTKQVYAIKVVPKSLMQKPHQREKMKQEIEIHRQLHHPNIVKFHHFFEDHENVYIVLEYCHNRSLMHYHKRRAKRLTEP

RTATIIQELSDALTYCHEKKVIHRDIKPENLLLGLNGEVKISDFGWSVHTPSL--RRKTMCGTLDYLPPEMI--AQKPYNEMVDLWCIGVLCYELLVGKP
 .  ..  .  .| | |....||||.|. ||.|  | .||| ||| ..       |.||||||  |  ||      ...   || | .|.  | ||.|||
EVRYYMYQIVQGLKYLHQHRIIHRDLKLGNLFLNDNMHVKIGDFGLATRLEYDGERKKTMCGTPNYIAPEVLDGNKQGHSYEVDCWSLGCIMYTLLIGKP

PFESSTSSETYRRIRQVDFKFPSS--VPAGAQDLISKLLRYHPSERLSLAQVLKHPWV
|||...  |||.||.. .. ||..  . . |.||| |.|.  |.||... |.| ||. 
PFETKDVKETYKRIKHNHYSFPEHCPISDEAKDLIQKMLNWNPDERPTIDQILQHPFF
Kinase AurC.AA RSK 58-305 30 2.1e-72 246.85 In-house 1-278 (278) Show / Hide 
Range on Protein: 58-305
Range on HMM: 1-278/278
Sequence Identity: 30% (86 aa)

GRPLGRGKFGRVYLARLK---ENHFIVALKVLFKSEIEKEG--LEHQLRREVEIQAHLQ-HRNILRLYNYFYDDTRIYLILEYAPGGELYKELQRHQK--
 . ||.| .| |.| | .    .  | | ||| |..| .    ..|  ..|..| .. | | .| .|.  | ... .|||.|| .||||.. ||...   
LKVLGQGGYGKVFLCRKCTHHDTGQIYAMKVLKKAKIVQRQKDTRH-TMTERNILERCQQHPFIVTLHYAFQTEGKLYLIMEYCRGGELFTHLQKEKHFG

-LDQQRTATIIQELSDALTYCHEKKVIHRDIKPENLLLGL---NGEVKISDFGWSVH-TPS--LRRKTMCGTLDYLPPEMIA---QKP-YNEMVDLWCIG
 ..  . . .. |.. |. . |....||||.|||| |.     .|..|..||| .    ..   . .| |.|..|..|||..   |.  ... .|.|  |
CFSEDEACFYMAEIVLAVEHLHQQGIIHRDLKPENILYDDESNEGHIKLTDFGFCKQFRCDHNQWTMTFCYTIEYMAPEMLKRANQQGGHDKACDWWSLG

VLCYELLVGKPPFES---STSSETYRRIRQVD--FKFP--SSVPAGAQDLISKLLRYHPSERLS-----LAQVLKHPWV
|| ||.|.|.||| .   ....|. .||.. .  ...|  ... . |.|||.|.|  .|. ||.     ......||| 
VLMYEMLTGCPPFQGPNDNNRKEIMKRIQKGKFSLTMPNWQYLSQEAKDLIRKMLHRDPHKRLGCGPQDAEEIKQHPWF
Kinase AurC.AA Pkinase_Tyr 55-198 32 2.8e-26 89.63 Pfam 1-156 (270) Show / Hide 
Range on Protein: 55-198
Range on HMM: 1-156/270
Sequence Identity: 32% (51 aa)

FEIGRPLGRGKFGRVYLARLK----ENHFIVALKVLFKSEIEKEG-LEHQLRREVEIQAHL-QHRNILRLYNYFY-DDTR--IYLILEYAPGGELYKELQ
 ..|. ||.| ||.||....|    ...  || |.| |    .|  .   . ||..|  .| .| ||.|||   . ..    ||...||.|.| |.. |.
ITFGKKLGEGAFGEVYKGTWKGDPDNTKIPVAVKML-KEGAMHEQNCREDFMREAKIMKQLGHHPNIVRLYGVCTDQGEPNQIYIVMEYMPHGDLLDYLR

RH----QKLDQQRTATIIQELSDALTYCHEKKVIHRDIKPENLLLGLNGEVKISDFG
.|    |.|. ..   . .. .... | ..|. ||||.   | |.. |. |||.|||
KHREDKQPLTMKDLLQMCWQIAKGMEYLESKNCIHRDLAARNCLVTENNVVKICDFG
Kinase AurC.AA TyrKc 55-303 22 4.2e-18 67.38 SMART 1-280 (280) Show / Hide 
Range on Protein: 55-303
Range on HMM: 1-280/280
Sequence Identity: 22% (66 aa)

FEIGRPLGRGKFGRVYLARLKENHFIVALKVLFKSEIEKEGLEHQLRREVEIQAHL--QHRNILRLYNYFYDD-------TRIYLILEYAPGGELYKELQ
 . |. ||.| ||.||....|     || |.| ..       .  ..|| .|  .|  .| ||.||| .  ..         .....||.|.| | . |.
ITLGKKLGEGAFGEVYKGTWK---IQVAVKMLKEDA------REDFMREARIMCKLGGHHPNIVRLYGVCTQQGRNFMYIEPLMIVMEYMPHGDLKDYLR

RHQK-LDQQRTATIIQELSDALTYCHEKKVIHRDIKPENLLLGLNGEVKISDFGWSVHTPSL-------RRKTM----CGT----LDYLPPEMIAQKPYN
.|.. |  .    .    ..   | |.|..||||.   | |.| |. ||||||| |    .          ...    .|     .  ..|| |  . ..
KHRPKLCMKDLLSFCWQIACGMEYLHSKNCIHRDLAARNCLVGENHTVKISDFGLSRDIYDDDQQGESKDYYRKKEHKGGKTMLPIRWMAPECINYGKFT

EMVDLWCIGVLCYELL-VGKPPFES-----STSSETYRRIRQVDFKFPSSV---------PAGAQDLISKLLRYHPSERLSLAQVLKHP
.  | |  ||...|..  |..| .       . .| .....| .   .            |.   .....  .. |..| . ... .  
TKSDVWSFGVCMWEIFTYGQQPYPGMIQQMMSNQEVIEYVKQGYRMPQPPNDYPMSFVCCPDEMYQIMKQCWHEDPEDRPTFSEIHECF