BRDT

Species: Mouse
Alias: BRDT, Fsrg3
External Links: MGI , Entrez Gene , Refseq cDNA , Refseq Protein , Phosphosite , iHOP
Annotation:

Classification

Group: Atypical
Family: BRD

Sequence

Name Sequence Type Origin Length Description Download
BRDT.AA Protein Sugen 956 None Fasta, JSON
BRDT.NA RNA Sugen 3385 None Fasta, JSON

Protein domain

Protein domains of BRDT.AA. The domains are annotated by HMM profiles from Pfam and SMART, as well as in-house data which includes HMMs of each individual kinase group, family and subfamily. Here is domain list in details, including sequence identity, significance and alignment. In particular, you can find can find the best hit kinase group/family/subfamily, which is helpful to understand the relationship between kinases.Kinase domain and best hit kinase group/family/subfamily are highlighted in red and blue. Visualized by pviz.

Usage: Zoom in selected region by dragging mouse and zoom out by double-clicking.

Domain Protein name Domain Name Range Identity (%) Significance Score Profile Source Profile Range (length) Alignment
BROMO BRDT.AA BROMO 24-134 40 1.1e-47 165.72 SMART 1-118 (118) Show / Hide
Range on Protein: 24-134
Range on HMM: 1-118/118
Sequence Identity: 40% (48 aa)

SGRLTNQLQFLQRVVLKALWKHG--------FSWPFQQPVDAVKLKLPDYYTIIKTPMDLNTIKKRLENKYYEKASECIEDFNTMFSNCYLYNKTGDDIV
. .  ...|.| ..|.... .||        ..|||.||||...|..|||| |||.||||.||||.||| .|  . | ..||. ||.||. ||. . .. 
DPK-QKKCQELLKEVMCHKHDHGDPMNRGRPYAWPFMQPVDRKELNYPDYYDIIKNPMDLKTIKKKLENHQYQSMEEFVDDFMLMFNNCMTYNEPDSEVY

VMAQALEKLFMQKLSQMPQ
 ||. |.|.|..|. ..|.
KMAKKLQKFFEEKWREFPP

Bromodomain BRDT.AA Bromodomain 35-120 34 4.8e-30 100.39 Pfam 1-89 (89) Show / Hide
Range on Protein: 35-120
Range on HMM: 1-89/89
Sequence Identity: 34% (31 aa)

QRVVLK--ALWKHGFSWPFQQPVDAVKLKLPDYYTIIKTPMDLNTIKKRLENKYYE-KASECIEDFNTMFSNCYLYNKTGDDIVVMAQA
 . ...   ...|....||..||| .. ..|||| |||.||||.||...|.|..|     | ..|.. |..||. ||. ...| ..|. 
CDQIMDMKYIMEHPICEPFWHPVDPDRDEYPDYYDIIKHPMDLSTIQQKLKNNKYRNNIAEFWHDMELMWHNCMTYNGPDSPIYKDARK

BROMO BRDT.AA BROMO 268-377 44 8.6e-43 149.4 SMART 1-118 (118) Show / Hide
Range on Protein: 268-377
Range on HMM: 1-118/118
Sequence Identity: 44% (53 aa)

VTEQLKHCSEILKEMLAKKHLP---------YAWPFYNPVDADALGLHNYYDVVKNPMDLGTIKGKMDNQEYKDAYEFAADVRLMFMNCYKYNPPDHEVV
  . .| |.|.|||....||           |||||..|||.. |....|||..||||||.||| |..| .|... ||..|..||| ||..||.||.|| 
DPK-QKKCQELLKEVMCHKHDHGDPMNRGRPYAWPFMQPVDRKELNYPDYYDIIKNPMDLKTIKKKLENHQYQSMEEFVDDFMLMFNNCMTYNEPDSEVY

AMARTLQDVFELHFAKIPD
 ||..||..|| .....|.
KMAKKLQKFFEEKWREFPP

Bromodomain BRDT.AA Bromodomain 275-363 40 2.6e-29 98.01 Pfam 1-89 (89) Show / Hide
Range on Protein: 275-363
Range on HMM: 1-89/89
Sequence Identity: 40% (36 aa)

CSEILKEMLAKKHLPYAWPFYNPVDADALGLHNYYDVVKNPMDLGTIKGKMDNQEYK-DAYEFAADVRLMFMNCYKYNPPDHEVVAMART
|..|.. |. ..  | ..||  ||| |  .. .|||..|.|||| ||. |..|..|.   .|| .|..||. ||..||.||... ..||.
CDQIMD-MKYIMEHPICEPFWHPVDPDRDEYPDYYDIIKHPMDLSTIQQKLKNNKYRNNIAEFWHDMELMWHNCMTYNGPDSPIYKDARK