Gene CaMK2g (Mouse)
CaMK2g
Sequence
Protein domains of CaMK2g.AA. The domains are annotated by HMM profiles from Pfam and SMART, as well as in-house data which includes HMMs of each individual kinase group, family and subfamily. Here is domain list in details, including sequence identity, significance and alignment. In particular, you can find can find the best hit kinase group/family/subfamily, which is helpful to understand the relationship between kinases.Kinase domain and best hit kinase group/family/subfamily are highlighted in red and blue. Visualized by pviz.
Usage: Zoom in selected region by dragging mouse and zoom out by double-clicking.
| Domain | Protein name | Domain Name | Range | Identity (%) | Significance | Score | Profile Source | Profile Range (length) | Alignment |
|---|---|---|---|---|---|---|---|---|---|
| Kinase | CaMK2g.AA | CAMK2 | 14-272 | 94 | 2.9e-223 | 748.02 | In-house | 1-259 (259) | Show / Hide |
Range on Protein: 14-272 Range on HMM: 1-259/259 Sequence Identity: 94% (244 aa) YQLFEELGKGAFSVVRRCVKKTSTQEYAAKIINTKKLSARDHQKLEREARICRLLKHPNIVRLHDSISEEGFHYLVFDLVTGGELFEDIVAREYYSEADA |||||||||||||||||||||...|||||||||||||||||||||||||||||.|||||||||||||.|||||||||||||||||||||||||||||||| YQLFEELGKGAFSVVRRCVKKCTGQEYAAKIINTKKLSARDHQKLEREARICRKLKHPNIVRLHDSIQEEGFHYLVFDLVTGGELFEDIVAREYYSEADA SHCIHQILESVNHIHQHDIVHRDLKPENLLLASKCKGAAVKLADFGLAIEVQGEQQAWFGFAGTPGYLSPEVLRKDPYGKPVDIWACGVILYILLVGYPP ||||.||||||||.||..|||||||||||||||||||||||||||||||||||.|||||||||||||||||||||||||||||||||||||||||||||| SHCIQQILESVNHCHQNGIVHRDLKPENLLLASKCKGAAVKLADFGLAIEVQGDQQAWFGFAGTPGYLSPEVLRKDPYGKPVDIWACGVILYILLVGYPP FWDEDQHKLYQQIKAGAYDFPSPEWDTVTPEAKNLINQMLTINPAKRITADQALKHPWV |||||||.|||||||||||.||||||||||||||||||||||||.||||||.||||||. FWDEDQHRLYQQIKAGAYDYPSPEWDTVTPEAKNLINQMLTINPKKRITADEALKHPWI |
|||||||||
| Kinase | CaMK2g.AA | CAMK1 | 14-272 | 42 | 1.1e-150 | 441.32 | In-house | 1-276 (276) | Show / Hide |
Range on Protein: 14-272 Range on HMM: 1-276/276 Sequence Identity: 42% (118 aa) YQLFEELGKGAFSVVRRCVKKTS---TQEYAAKIIN-TKKLSARDH---QKLEREARICRL---LKHPNIVRLHDSISEEGFHYLVFDLVTGGELFEDIV |....|.|.||||.|..|..| . ..|| |.|. | .. | ..||.| | . ..||||. ... .. . ||| .||||||||. || YEFGKEIGRGAFSEVYLCTHKETQTNGKQYAIKCIDKKKFMKKKDMQKQEALENEIEIMKKVSKIDHPNIIKFYEWYESDNHFYLVMELVTGGELFDRIV AREYYSEADASHCIHQILESVNHIHQHDIVHRDLKPENLLLASKCKGAAVK--LADFGLAIEVQGEQQAWFGFAGTPGYLSPEVLRK---DPYGKPVDIW ...|.| ||.|...|||. |...|...||||||||||||...| .. .| .|||||. . .. . ||||| |||| .||.|..|.| EKGNYTEKDARHIMKQILSAVEYMHSKGIVHRDLKPENLLYYDKDEDSKIKRSIADFGLSKIFDHDENLMKTACGTPGYVAPEVLECKKDKPYDKACDMW ACGVILYILLVGYPPFWDED-QHKLYQQIKAGAYDFPSPEWDTVTPE-AKNLINQMLTINPAKRITADQALKHPWV .|||.||||.|||||.||. ...|...|| . |.||||.|| . . ||..|..||. .| ||.|..|.|.|||. SIGVITYILLCGYPPFYDENVDNELFEKIKKCEYEFPSPWWDNISDQEAKDFIKHMLEVDPKKRYTCEQCLNHPWI |
|||||||||
| Kinase | CaMK2g.AA | CAMK | 19-272 | 26 | 3.7e-134 | 435.01 | In-house | 1-425 (425) | Show / Hide |
Range on Protein: 19-272
Range on HMM: 1-425/425
Sequence Identity: 26% (112 aa)
ELGKGAFSVVRRCVKKTST------------QEYAAKIINTKKLS--------------------------ARDHQKLEREARICRL-------LKHPNI
.||.|.|..|..|. | .| |..|.|||..|||. ..| ....|| .|... |.||||
TLGRGSFGKVKLCIHKNTTGKERVHHIYTNGQKVAIKIIDKKKLKDKQNQDYSNCYKIDKSKCKHRYCWRRPKDRKNVRREIEIMKKLQGIGNKLDHPNI
VRLHDSISEEGF-------------------HYLVF---DLVTGGEL----FEDIVAREY---------------YSEADASHCIHQILESVNHIHQHDI
..|.. . . . |.|. ....|||| |. ||.... ..|..|.....||.. |...|.|.|
IKLYEVYEDPHYFKNTNDYETSKQVFTKDKHMYMVMEIMEYCSGGELFDDLFDYIVEHGCYGEEFDQFDIVERGRFTEREARRYFRQICSAVHYCHSHNI
VHRDLKPENLLLASKCKG--------------AAVKLADFGLAIEVQG-----------------------EQQAWFGFAGTPGYLS-PEVLRK------
|||||||||.|| .. .. . .|..|||.|..... | | | |||.| . ||||..
VHRDLKPENILLDDNNDDSDPVEHDEIFDWNNNNIKIIDFGFANKFDPGENNFMCSDYKGGEMHNQWTTPTEGQKMKTFCGTPEYMAAPEVLNGKGHCNM
--------DPYGKPVDIWACGVILYILLVGYPPFWDE-------------DQHKLYQQIKAGAYDFPSPE------------WDTVTPE--------AKN
..||...|.|.|||||||.|.|||||... ....|...|..| ||||.|. || .. | .|.
QNATDEEKPYYGPKCDMWSCGVILYIMLCGYPPFYGDCDNEICEDEWIGMNDYELFEKIMKGKYDFPPPYFSPISCNYGPEWWDDISDEFHHFVSQECKD
LINQMLTINPAKRITADQALKHPWV
||..||. .| ||.|..|.|.|||.
LIRKMLQVDPEKRMTIEQCLNHPWM
|
|||||||||
| Kinase | CaMK2g.AA | RAD53 | 14-272 | 35 | 1.5e-112 | 336.62 | In-house | 1-305 (305) | Show / Hide |
Range on Protein: 14-272 Range on HMM: 1-305/305 Sequence Identity: 35% (108 aa) YQLFEELGKGAFSVVRRCVKKTSTQEYAAKIINTKKLS---ARD---HQKLEREARICRLLKHPNIVRLHDSISE-EGFHYLVFDLVTGGELFEDIVARE | . .|||.|.|..|.....|. | .| |||..||.. .. ...|..| . |.||.|.|..|.. . . |.| |.||||||..||... YYMSKELGSGNFGTVKLAYEKKTCQKVAIKIIDKKKFFIRCMHTIKKMDQVMNEVEILKKLNHPCIIRIYDIFDTPQKYYYMVLELMTGGELFNKIVSNK Y----YSEADASHCIHQILESVNHIHQHDIVHRDLKPENLLLASKCKGA---------------AVKLADFGLAIEVQGEQQAWFGFAGTPGYLSPEVLR . ..|... |....|. .| |.|||||||| |.... .. ..|..||||. ..||.. . ||| |. |||.. RCQMGFDEDTCKYYFYQMCDAVKYLHDNGICHRDLKPENILCNHQDEECPQVQLGPWDEDEISFLIKITDFGLS-KFVGEGSFMKTMCGTPQYVAPEVIT KD---------------PYGKPVDIWACGVILYILLVGYPPFWDE-DQ----HKLYQQIKA-GAYDFPSPEWDTVTPEAKNLINQMLTINPAKRITADQA . |.| ||.| |.||||.| ||||| |. .| .|..||| | | ||.|.|| .. |||.||..||...| ||.|.|.| SKGHNCYHENEERQVQVGYTKKVDCWSMGCILYICLCGYPPFSDDYTQEMHCMQLFEQIKNQGKYHFPHPYWDRISEEAKDLIKWMLCVDPEKRYTIDEA LKHPWV | ||| LNHPWM |
|||||||||
| Kinase | CaMK2g.AA | CDPK | 14-272 | 40 | 6.30000000001e-112 | 344.51 | In-house | 1-271 (271) | Show / Hide |
Range on Protein: 14-272 Range on HMM: 1-271/271 Sequence Identity: 40% (109 aa) YQLFEELGKGAFSVVRRCVKK-TSTQEY-AAKIINTKKLSARDH-QKLEREARICRLLKHPNIVRLHDSISEEGFHYLVFD--LVTGGELFEDIVAREYY |.. ..||||.|..||....| . || | |||. .... . |.. .| | . | ||||... | ..|.|. ..||||||. |... .. YKIKKVLGKGHFGQVRKVKHKQKTNQERVAMKIIPKSRVKDKEQQQQFFNEIEILKQLDHPNIIKIYEFYQDEKNYYIVMETEYCTGGELFDYIIEKGHF SEADASHCIHQILESVNHIHQHDIVHRDLKPENLLLASKCKGA----AVKLADFGLAIEVQGE----QQAWFGFAGTPGYLSPEVLRKDPYGKPVDIWAC .| .|. . ||| ||..|.. ||||||||||.|. || ... .|. |.|.. . ... . ..||| |..||||.| | . .||| | TEKEAAYIMRQILSAVNYCHSNNIVHRDLKPENILFDSKKDDSWVIYNIKVIDWGTSKKFDQNQKIEDKKMSQRCGTPYYIAPEVLQKK-YNEKCDIWSC GVILYILLVGYPPFWDEDQHKLYQQIKAGAYDFPSPEWDTVTPEAKNLINQMLTINPAKRITADQALKHPWV ||||||||.|||||. . . . ....| | |.| |||| .. |||.||..||. .| ||..|.|||.|||. GVILYILLCGYPPFYGKNDQEIMEKVKKGKYSFEGPEWDHISDEAKDLIRKMLCYDPKKRMSAQQALQHPWF |
|||||||||
| Kinase | CaMK2g.AA | S_TKc | 14-272 | 34 | 3.7e-108 | 366.55 | SMART | 1-231 (231) | Show / Hide |
Range on Protein: 14-272 Range on HMM: 1-231/231 Sequence Identity: 34% (96 aa) YQLFEELGKGAFSVVRRCVKKTSTQEYAAKIINTKKLSARDHQKLEREARICRLLKHPNIVRLHDSISEEGFHYLVFDLVTG--GELFEDIVAREY---- |.. ...|||||..|..|..| . ...| |||. ....|| .|.. .|||||.|.|.. . .. |.|.... | |.||. |. | . YEILRKIGKGAFGKVYKCRHKKTGRIVAIKIIK---------EHIRREIQILKK-HHPNIVKLYDVFQD-DHLYMVMEYCDGDLGDLFDYIKKRGRHGLR --YSEADASHCIHQILESVNHIHQHDIVHRDLKPENLLLASKCKGAAVKLADFGLAIEVQGEQQAWFGFAGTPGYLSPEVLRKDPYGK-PVDIWACGVIL ..| .| . ..||.. ....|.| |.||||||||.|| . .|..||||| .. | ||| |..|||| .||| ..|.|.||.|| FPFPE-HARFYMYQICCALEYCHSHGIIHRDLKPENILLDE-----HIKICDFGLARQL-------TTFCGTPWYMAPEVL---GYGKCKCDWWSCGCIL YILLVGYPPFWDEDQHKLYQQIKAGAYDFPSPEWDTVTPEAKNLINQMLTINPAKRITADQALK-------HPWV |..|.|||||. ........|. .||||..|...|. .|.||.|| .||. |||. YEMLCGYPPFP--QMQMMFKKIG--------------SPEAKDFIRKCLQKDPEKRPTA-EALQDEWDIKCHPWF |
|||||||||
| Kinase | CaMK2g.AA | DCAMKL | 14-272 | 38 | 9.40000000001e-105 | 326.87 | In-house | 1-279 (279) | Show / Hide |
Range on Protein: 14-272 Range on HMM: 1-279/279 Sequence Identity: 38% (109 aa) YQLFEELGKGAFSVVRRCVKKTST-QEYAAKI-----------------INTKKLSARDHQKLEREARICRLLKHPNIVRLHDSISEEGFHYLVFDLVTG ||. |.| |.|| |.... ..|| || |. .|. | . | .| ...|||.|..|... . | |||. .|.| YQIGRIIGDGNFAVVHECRHRETGDHKYAMKIRYQSTLQFSFPSKFFQQIDKRKCKGKEHM-IDNEVSIMQKIKHPHIIQLYEHWDTETHYYLVMEYVQG GELFEDIVAREYYSEADASHCIHQILESVNHIHQHDIVHRDLKPENLLLAS-KCKGAAVKLADFGLAIEVQGEQQAWFGFAGTPGYLSPEVLRKDPYGKP | ||. |. ..| ||. .... . ...| |||||.||||||. . .||.||||| .|.|. . ||| | ||.|.. || GDLFDAITENTKFTERDAAIMMTCLCKALKYLHEMNIVHRDIKPENLLVCKHEDGEKSLKLCDFGLACHVNGDFGPLYTVCGTPTYVAPEILMETGYGCK VDIWACGVILYILLVGYPPFWDE--DQHKLYQQIKAGAYDFPSPEWDTVTPEAKNLINQMLTINPAKRITADQALKHPWV ||||| ||||||||.|.||| . || .| || .|...||.|.|| .. ||.||..|| .| || || | ..|||| VDIWAAGVILYILLCGFPPFRSPDNDQEELFDQIMQGKFEFPMPYWDNISDSAKDLISHMLQVDPEKRYTAEQIMQHPWV |
|||||||||
| Kinase | CaMK2g.AA | Pkinase | 14-272 | 33 | 4.2e-97 | 333.69 | Pfam | 1-293 (293) | Show / Hide |
Range on Protein: 14-272 Range on HMM: 1-293/293 Sequence Identity: 33% (99 aa) YQLFEELGKGAFSVVRRCVKKTSTQEYAAKIINTKKLSARDHQKLER--EARICRLLKHPNIVRLHDSISEEGFHYLVFDLVTGG----ELFEDIV--AR |.. . .|.|.|..|..|..| . ...| |||. .. . .| . | |..| . |.|||||||.|. ... |.|.... || .||. | .. YHIGRKIGSGSFGCVYKCHHKGTGKIVAVKIIKKRHEKSWKDQTHRRLSEIQIMKRLNHPNIVRLYDWFEDKDHIYMVMEYCEGGLYVMDLFDYISTWRH EYY--SEADASHCIHQILESVNHIHQHDIVHRDLKPENLLLASKCKG-AAVKLADFGLAIEV-QGEQQAWFGFAGTPGYLSPEVLR-KDPYGKPVDIWAC . || .. ... |||. ....|.. |.||||||||.|. ... | ||..||||| . .. .|.|||.|..|||.| .||..||.|.| GCFYFSEWECKFYMYQILRGLEYCHSMGIIHRDLKPENILIDNNGHIDACVKICDFGLAKQFDY-NNS-MTTFCGTPWYMAPEVIRGGQYYGPKVDMWSC GVILYILLVGYPPFWDE------DQHKLYQQIKAGAYDFPSPEWDTVT-----------------PEAKNLINQMLTINPAKRITADQALKHPWV |.|||..| |.|||... || .....|. . ..|..|.|... .|.| .|. .|. .|.||.||.|.|.|||. GCILYEMLCGRPPFPGHCWHDNHDQMQMICRIMGPPLHFDWPWWCSISYFFFRHWHFHWTFHNWSEECKDFIKWCLCKDPKKRPTAEQILQHPWF |
|||||||||
| Kinase | CaMK2g.AA | CAMKL | 14-272 | 34 | 2.2e-94 | 301.62 | In-house | 1-297 (297) | Show / Hide |
Range on Protein: 14-272 Range on HMM: 1-297/297 Sequence Identity: 34% (104 aa) YQLFEELGKGAFSVVRRCVK-KTSTQEYAAKIINTKKLS--------------ARDHQKLEREARICRLLK---HPNIVRLHDSISEEGF------HYLV |.. ..||||.|..|. .. .| ...| |||. ||.. .| ...||..| ..|. ||||..|.. | . . ||| YRIGKTLGKGSFGKVKLATHIRTTGEKVAIKIIDKKKIWNDPWMKKNKCGQKHESDM-RIRREIQIMKMLNIGKHPNIIKLYEVIETPEHDIETKKIYLV FDLVTGGE--LFEDIVAREY----YSEADASHCIHQILESVNHIHQHDIVHRDLKPENLLLASKCKGAAVKLADFGLAIE---V-QGEQQAWFGFAGTPG .. ||| ||. ||.... .| .| . ||.. ||..|.|.|||||.||||.|| .. . .|..|||.... . |. | | |.| MEYCSGGEMDLFDYIVKHGHRRGRMPEHEARRYFRQIVSAVNYCHSHGIVHRDIKPENILLDENGNN-NIKIIDFGFSNMYRPCIFGPGQKLKTFCGSPP YLSPEVLRK--DPYG-KPVDIWACGVILYILLVGYPPFWDE--------DQHKLYQQIKAGAYDFPSPEWDTVTPEAKNLINQMLTINPAKRITADQALK | .||.. . .|| ..||||.|||||| ...|| || |. .. .|| .|. | | .| | | ....|| .||. || ||.|..| .. YMAPEIFQGNNKPYDGPKVDIWSCGVILYAMVCGYLPFDDDTYNKQGKDNI-YLYWKIMCG-YYPP--IWYHVS-DCRDLIRKMLQVNPEKRPTIHQIMN HPWV |||. HPWM |
|||||||||
| Kinase | CaMK2g.AA | RSK | 16-272 | 31 | 5.7e-92 | 311.86 | In-house | 1-278 (278) | Show / Hide |
Range on Protein: 16-272 Range on HMM: 1-278/278 Sequence Identity: 31% (87 aa) LFEE--LGKGAFSVVRRCVKKTSTQEYAAKIINTKKLSARDH-QKLER-EARICRLLK-HPNIVRLHDSISEEGFHYLVFDLVTGGELFEDIVAREY--- | . .|.|.....|.|. . . |.|| |... .|. .|. .. . | .| . . ||.||.||.. .|| ||. ... |||||. . ... LKVLGQGGYGKVFLCRKCTHHDTGQIYAMKVLKKAKIVQRQKDTRHTMTERNILERCQQHPFIVTLHYAFQTEGKLYLIMEYCRGGELFTHLQKEKHFGC YSEADASHCIHQILESVNHIHQHDIVHRDLKPENLLLASKCKG-AAVKLADFGLAIE-VQGEQQAWFGFAGTPGYLSPEVLR---KDP-YGKPVDIWACG || .|. . .| | |.||..|.|||||||| |.... . . .|| |||.. . . . | | .| |. ||.|. .. ..| .|.| | FSEDEACFYMAEIVLAVEHLHQQGIIHRDLKPENILYDDES-NEGHIKLTDFGFCKQFRCDHNQWTMTFCYTIEYMAPEMLKRANQQGGHDKACDWWSLG VILYILLVGYPPFWD---EDQHKLYQQIKAGAYDFPSPEWDTVTPEAKNLINQMLTINPAKRIT-----ADQALKHPWV |..| .|.|.||| ...... ..|. | .....|.|.....|||.||..||. .|.||.. |.. ..||| VLMYEMLTGCPPFQGPNDNNRKEIMKRIQKGKFSLTMPNWQYLSQEAKDLIRKMLHRDPHKRLGCGPQDAEEIKQHPWF |
|||||||||
| Kinase | CaMK2g.AA | CAMK-Unique | 14-272 | 23 | 1.8e-91 | 302.18 | In-house | 1-363 (363) | Show / Hide |
Range on Protein: 14-272
Range on HMM: 1-363/363
Sequence Identity: 23% (85 aa)
YQLFEELGKGAFSVVRRCVKKTSTQEYAAKIINTKKLS-ARDHQ-----------------KLEREARICRLLKHPNIVRLHDS----ISEEG-------
| . . .|.|.|..|..| .. ..| |... .. . . .| ||.||..| ....||||..| | .
YKMHRIIGHGNFGHVYECMDRETGKKWACKMVKKQTHGNKKQKQQRNFDLRYKITEKRRDMKLKREHQIWKMVDHPNIIKLYDWNNPIFCDRKYPLCDLI
--------FHYLVFDLVTGGELFEDIVA--------------------REYYSE--ADASHCIHQILESVNHIHQHDIVHRDLKPENLLLASK-------
|.| ....||.||. |.. . ..|| .|.. . ..|. |.. |. ||||||||.||... .
IKTPRALPYMYIVMEYCQGGDLFDWIQKWDEFYFNFIIKFDFNILKRCQGHFSERCWDTCFIMQCLLSAVAYMHSQDIVHRDLKLENIMVCYSFKDNNHH
------CKGAAVKLADFGLAIEVQGEQQA--WFGFAGTPGYLSP--------------EVLRKDPYGKPV----DIWACGVILYILLVGYPPFWDEDQH-
.. .||.||||. .... . . ||| |..| ||. ..|. .. |||..|||.|..|.|.||| |.
RDFPYDWSNWHIKLCDFGLCCHYNHNKMCHMMQTMCGTPCYMAPEIVFCKNYQEMTRDEVINMQCYDQQCSPASDIWSLGVIMYYMLCGCPPFDCECEDR
-------KLYQQIKAGAY-DFPSPEWDT---VTPEAKNLINQMLTINPAKRITADQALKHPWV
.... |..| | .|... |. ...|||... . .|. |..|..| ..|.|.|.
DYENHDKEIFECICKGDYCNFDWKMWHGPDYISQEAKDFVKCCMTVDPDHRWSAKELLEHQWI
|
|||||||||
| Kinase | CaMK2g.AA | Ciliate-E2 | 14-272 | 25 | 2.2e-86 | 293.27 | In-house | 1-365 (365) | Show / Hide |
Range on Protein: 14-272
Range on HMM: 1-365/365
Sequence Identity: 25% (97 aa)
YQLFEELGKGAFSVVRRC-VKKTST----------------------QEYAAKIINTKKLSARDH-QKLEREAR----------ICRLLKHPNIVRLHDS
| . . .|.|.|..|..| |.|. ..|| ||.. ... . ... || . |...|.||||......
YKFIKKIGQGNFGSVYKCKVWKVQKQFAIKIIDQKQQRQQMQEKVKIKIYAMKIMKKNQIEQIKQEIHIMREINCFYKKINEKNILEQLNHPNIIKMYEC
IS--EEGFHYLVFDLVTGGELFEDIV------------AREYYSEADASHCIHQILE---------------SVNHIHQHD-IVHRDLKPENLLLASKCK
. |||.... ||.||. | . .|..| ... . |||. ....|. |.|||.||||.|.
FQEKDDNNIYLVMEYCQGGDLFDYIKNNKKKRNHEIEKD-KYFTEKEIKYIMKQILQGFKTKAEFYIACIILALEYLHSKNNIIHRDIKPENILF-----
GAAVKLADFGLAIEVQGE-------------------------------QQAWFGFAGTPGYLSPEVLRKDP---------YGKPVDIWACGVILYILLV
.|..||||. ... . |. . ..|||||..||.|.. . |.. .|||..|||||..|
---IKIIDFGLSKKYDDDNQNRTHKQQCKWYMFKNDTSRTPGYMDQIIQQNMFNTICGTPGYMAPEILNGKKYDNQQKQKGYDYKCDIWSLGVILYEMLF
GYPPFWDEDQHKLYQQIKAGAYDFPSPE--------------WDTVTPEAKNLINQ----MLTINPAKRIT-ADQALKHPWV
|.||| .|||| . .|||.|| |. ...|.|.||.. || .| |||| ..|.|.|||
GKPPF--------QQQIKQCKIDFPCPEWQKDTQCIQCKWKSWKKWSQECKDLIKKFGKRMLQKDPEKRITGWEQILNHPWF
|
|||||||||
| Kinase | CaMK2g.AA | TyrKc | 14-270 | 20 | 4.8e-15 | 20.6 | SMART | 1-280 (280) | Show / Hide |
Range on Protein: 14-270 Range on HMM: 1-280/280 Sequence Identity: 20% (60 aa) YQLFEELGKGAFSVVRRCVKKTSTQEYAAKIINTKKLSARDHQKLEREARICRLL--KHPNIVRLHDSISEE-------GFHYLVFDLVTGGELFEDIVA .| ..|| ||| .|.... | .. | | .. . .. . ||||| . | .|||||||. .... . ...|. .. .| | . . . ITLGKKLGEGAFGEVYKGTWK---IQVAVKMLKEDA-----REDFMREARIMCKLGGHHPNIVRLYGVCTQQGRNFMYIEPLMIVMEYMPHGDLKDYLRK REY-YSEADASHCIHQILESVNHIHQHDIVHRDLKPENLLLASKCKGAAVKLADFGLAIEVQGE-----QQAWFGFA---GTPG-----YLSPEVLRKDP .. . .| . .|| . ...|.. ..|||| | |.... || .||||. .. . . . |. . ..||.... HRPKLCMKDLLSFCWQIACGMEYLHSKNCIHRDLAARNCLVGENH---TVKISDFGLSRDIYDDDQQGESKDYYRKKEHKGGKTMLPIRWMAPECINYGK YGKPVDIWACGVILY-ILLVGYPPFWD-----EDQHKLYQQIKAGAYDFPSPE-----WDTVTPEAKNLINQMLTINPAKRITADQALKHP . |.|. || .. |. | .| .. . .....|.| . . |. . ..| ... | .|..| | . . FTTKSDVWSFGVCMWEIFTYGQQPYPGMIQQMMSNQEVIEYVKQGYRMPQPPNDYPMSFVCCPDEMYQIMKQCWHEDPEDRPTFSEIHECF |
|||||||||
| Kinase | CaMK2g.AA | Pkinase_Tyr | 14-98 | 26 | 5.2e-08 | 27.76 | Pfam | 1-94 (270) | Show / Hide |
Range on Protein: 14-98 Range on HMM: 1-94/270 Sequence Identity: 26% (25 aa) YQLFEELGKGAFSVVRRCVKK----TSTQEYAAKIINTKKLSARD--HQKLEREARICRLL-KHPNIVRLHDSIS-EEGF--HYLVFDLVTGGEL .. ..||.||| .|.... | ... | |.. . . .. .... |||.| . | .|||||||. .. ... .|.|. .. .| | ITFGKKLGEGAFGEVYKGTWKGDPDNTKIPVAVKML-KEGAMHEQNCREDFMREAKIMKQLGHHPNIVRLYGVCTDQGEPNQIYIVMEYMPHGDL |
|||||||||
| Kinase | CaMK2g.AA | Pkinase_Tyr | 125-167 | 30 | 0.155631 | 5.82 | Pfam | 125-164 (270) | Show / Hide |
Range on Protein: 125-167 Range on HMM: 125-164/270 Sequence Identity: 30% (13 aa) NHIHQHDIVHRDLKPENLLLASKCKGAAVKLADFGLAIEVQGE .. ... ..|||| | |... . || .||||| .. . EYLESKNCIHRDLAARNCLVTE---NNVVKICDFGLARDIYND |
|||||||||
| CaMKII_AD | CaMK2g.AA | CaMKII_AD | 456-583 | 63 | 1.4e-86 | 298.72 | Pfam | 1-128 (128) | Show / Hide |
Range on Protein: 456-583 Range on HMM: 1-128/128 Sequence Identity: 63% (81 aa) RKQEIIKITEQLIEAINNGDFEAYTKICDPGLTSFEPEALGNLVEGMDFHKFYFENLLSKNSKPIHTTILNPHVHVIGEDAACIAYIRLTQYIDGQGRPR .||||.|.||..||||..||...|||.|.|..| ||.||.|||||||.||.||||....|..|..|||.|||||| .|.||||.||.|||||.| .| .. EKQEIWKVTERWIEAIYCGDWHTYTKLCHPDMTCFEWEACGNLVEGMEFHRFYFEMHWTKRCKAVHTTMLNPHVHMYGDDAACCAYVRLTQYMDKNGMAH TSQSEETRVWHRRDGKWLNVHYHCSGAP | |||||||||.|||||..|| | |..| TRQSEETRVWHKRDGKWQCVHHHRSAMP |
|||||||||