Gene CaMK4 (Mouse)

CaMK4

Species: Mouse
Alias: CaMK4, Camk4
External Links: MGI , Entrez Gene , Refseq cDNA , Refseq Protein , Phosphosite , iHOP
Annotation:

Classification

Group: CAMK
Family: CAMK1

Sequence

Name Sequence Type Origin Length Description Download
CaMK4.kin_dom Protein Kinase Domain Sugen global kinase HMM prediction 255 Kinase domain by global Sugen HMM Fasta, JSON
CaMK4.AA Protein Sugen 469 None Fasta, JSON
CaMK4.NA RNA Sugen 12331 None Fasta, JSON

Protein domain

Protein domains of CaMK4.AA. The domains are annotated by HMM profiles from Pfam and SMART, as well as in-house data which includes HMMs of each individual kinase group, family and subfamily. Here is domain list in details, including sequence identity, significance and alignment. In particular, you can find can find the best hit kinase group/family/subfamily, which is helpful to understand the relationship between kinases.Kinase domain and best hit kinase group/family/subfamily are highlighted in red and blue. Visualized by pviz.

Usage: Zoom in selected region by dragging mouse and zoom out by double-clicking.

Show/hide domain list
Domain Protein name Domain Name Range Identity (%) Significance Score Profile Source Profile Range (length) Alignment
Kinase CaMK4.AA CAMK1 42-296 52 1.2e-200 589.07 In-house 1-276 (276) Show / Hide 
Range on Protein: 42-296
Range on HMM: 1-276/276
Sequence Identity: 52% (146 aa)

FEVESELGRGATSIVYRCKQKGT---QKPYALKVLK-KTVDKK-------IVRTEIGVLL---RLSHPNIIKLKEIFETPTEISLVLELVTGGELFDRIV
.|. .|.|||| |.||.|..| |   .|.||.|... |.. ||        ...||...    ...||||||..|..|..... ||.|||||||||||||
YEFGKEIGRGAFSEVYLCTHKETQTNGKQYAIKCIDKKKFMKKKDMQKQEALENEIEIMKKVSKIDHPNIIKFYEWYESDNHFYLVMELVTGGELFDRIV

EKGYYSERDAADAVKQILEAVAYLHENGIVHRDLKPENLLYATPAPDAPLK--IADFGLSKIVEHQV-LMKTVCGTPGYCAPEILRG---CAYGPEVDMW
|||.|.|.||.. .||||.|| |.|..||||||||||||||... .|...|  |||||||||..|.. ||||.||||||.|||.| .   ..|. ..|||
EKGNYTEKDARHIMKQILSAVEYMHSKGIVHRDLKPENLLYYDKDEDSKIKRSIADFGLSKIFDHDENLMKTACGTPGYVAPEVLECKKDKPYDKACDMW

SVGIITYILLCGFEPFYDERGDQFMFRRILNCEYYFISPWWDEVSLN-AKDLVKKLIVLDPKKRLTTFQALQHPWV
|.|.||||||||..|||||..|...|. |..||| |.|||||..|   |||..|.....|||||.|  |.|.|||.
SIGVITYILLCGYPPFYDENVDNELFEKIKKCEYEFPSPWWDNISDQEAKDFIKHMLEVDPKKRYTCEQCLNHPWI
Kinase CaMK4.AA CAMK 47-296 27 4.1e-133 431.56 In-house 1-425 (425) Show / Hide 
Range on Protein: 47-296
Range on HMM: 1-425/425
Sequence Identity: 27% (118 aa)

ELGRGATSIVYRCKQKGTQ------------KPYALKVLKK------------------------------TVDKKIVRTEIGVLLRLS-------HPNI
.||||. ..|..|..| |.            . .| |...|                               .|.| || || .. .|.       ||||
TLGRGSFGKVKLCIHKNTTGKERVHHIYTNGQKVAIKIIDKKKLKDKQNQDYSNCYKIDKSKCKHRYCWRRPKDRKNVRREIEIMKKLQGIGNKLDHPNI

IKLKEIFET-------------------PTEISLVL---ELVTGGEL----FDRIVEK---------------GYYSERDAADAVKQILEAVAYLHENGI
||| |..|.                   .... .|.   |...||||    ||.|||.               |...||.|.  ..||..||.|.|...|
IKLYEVYEDPHYFKNTNDYETSKQVFTKDKHMYMVMEIMEYCSGGELFDDLFDYIVEHGCYGEEFDQFDIVERGRFTEREARRYFRQICSAVHYCHSHNI

VHRDLKPENLLYATPAPD--------------APLKIADFGLSKIVEH------------------------QVLMKTVCGTPGYCA-PEILRG------
|||||||||.|. .  .|              ...||.|||.......                          .|||.||||.|.| ||.|.|      
VHRDLKPENILLDDNNDDSDPVEHDEIFDWNNNNIKIIDFGFANKFDPGENNFMCSDYKGGEMHNQWTTPTEGQKMKTFCGTPEYMAAPEVLNGKGHCNM

--------CAYGPEVDMWSVGIITYILLCGFEPFYDER------------GDQFMFRRILNCEYYFISPW------------WDEVSLN--------AKD
          |||..||||.|.|.||.|||. |||..              |. .|..|....|.|..|.            ||..| .        .||
QNATDEEKPYYGPKCDMWSCGVILYIMLCGYPPFYGDCDNEICEDEWIGMNDYELFEKIMKGKYDFPPPYFSPISCNYGPEWWDDISDEFHHFVSQECKD

LVKKLIVLDPKKRLTTFQALQHPWV
|..|. . ||.||.|  |.|.|||.
LIRKMLQVDPEKRMTIEQCLNHPWM
Kinase CaMK4.AA RAD53 42-296 37 1.1e-130 391.75 In-house 1-305 (305) Show / Hide 
Range on Protein: 42-296
Range on HMM: 1-305/305
Sequence Identity: 37% (113 aa)

FEVESELGRGATSIVYRCKQKGTQKPYALKVLKK--------TV--DKKIVRTEIGVLLRLSHPNIIKLKEIFETP-TEISLVLELVTGGELFDRIVEKG
. .  |||.|. ..|.... | | . .| | ..|        ..  ... |..|. .| .|.||.||....||.|| .  ..||||.||||||..||  .
YYMSKELGSGNFGTVKLAYEKKTCQKVAIKIIDKKKFFIRCMHTIKKMDQVMNEVEILKKLNHPCIIRIYDIFDTPQKYYYMVLELMTGGELFNKIVSNK

Y----YSERDAADAVKQILEAVAYLHENGIVHRDLKPENLLYATPAPDA---------------PLKIADFGLSKIVEHQVLMKTVCGTPGYCAPEILR-
.    ..| .. .  .|...|| |||.|||.|||||||| |..... .                 .||.||||||.|. . .||| |||| |.|||... 
RCQMGFDEDTCKYYFYQMCDAVKYLHDNGICHRDLKPENILCNHQDEECPQVQLGPWDEDEISFLIKITDFGLSKFVGEGSFMKTMCGTPQYVAPEVITS

-GC-------------AYGPEVDMWSVGIITYILLCGFEPFYDERGD----QFMFRRILN-CEYYFISPWWDEVSLNAKDLVKKLIVLDPKKRLTTFQAL
 |              .|...||.|| | |.||.|||. || |....      .|  |.|   | |..| ||..| .||||.|.....||.||.|. .||
KGHNCYHENEERQVQVGYTKKVDCWSMGCILYICLCGYPPFSDDYTQEMHCMQLFEQIKNQGKYHFPHPYWDRISEEAKDLIKWMLCVDPEKRYTIDEAL

QHPWV
.||| 
NHPWM
Kinase CaMK4.AA Pkinase 42-296 38 3.4e-117 400.42 Pfam 1-293 (293) Show / Hide 
Range on Protein: 42-296
Range on HMM: 1-293/293
Sequence Identity: 38% (113 aa)

FEVESELGRGATSIVYRCKQKGTQKPYALKVLKKTVDKKIVR------TEIGVLLRLSHPNIIKLKEIFETPTEISLVLELVTGG----ELFDRIV--EK
..... .|.|. . ||.|. |||.| .|.|..||  .|. ..      .|| ...||.||||..|...||....| .|.|.. ||    .|||.|   ..
YHIGRKIGSGSFGCVYKCHHKGTGKIVAVKIIKKRHEKSWKDQTHRRLSEIQIMKRLNHPNIVRLYDWFEDKDHIYMVMEYCEGGLYVMDLFDYISTWRH

GYY--SERDAADAVKQILEAVAYLHENGIVHRDLKPENLLYA-TPAPDAPLKIADFGLSKI--VEHQVLMKTVCGTPGYCAPEILR-GCAYGPEVDMWSV
| .  ||... . ..|||....|.|..||.||||||||.|.  .. .||..||.||||.|     ... |.|.||||.|.|||..| |  |||.|||||.
GCFYFSEWECKFYMYQILRGLEYCHSMGIIHRDLKPENILIDNNGHIDACVKICDFGLAKQFDY-NNS-MTTFCGTPWYMAPEVIRGGQYYGPKVDMWSC

GIITYILLCGFEPFYDE-----RGDQFMFRRILNCEYYFISPWWDEVS-----------------LNAKDLVKKLIVLDPKKRLTTFQALQHPWV
|.| |..|||  ||...     . ...|..||. ... | .|||...|                  ..||..|... .|||||.|  |.|||||.
GCILYEMLCGRPPFPGHCWHDNHDQMQMICRIMGPPLHFDWPWWCSISYFFFRHWHFHWTFHNWSEECKDFIKWCLCKDPKKRPTAEQILQHPWF
Kinase CaMK4.AA S_TKc 42-296 36 5.3e-108 366.01 SMART 1-231 (231) Show / Hide 
Range on Protein: 42-296
Range on HMM: 1-231/231
Sequence Identity: 36% (99 aa)

FEVESELGRGATSIVYRCKQKGTQKPYALKVLKKTVDKKIVRTEIGVLLRLSHPNIIKLKEIFETPTEISLVLELVTG--GELFDRIVEKGY------YS
.|.  ..|.|| . ||.|. |.|.. .|.|..|     . .| || .| .  ||||.||...|.. ... .|.|.. |  |.|||.|...|.      ..
YEILRKIGKGAFGKVYKCRHKKTGRIVAIKIIK-----EHIRREIQILKK-HHPNIVKLYDVFQD-DHLYMVMEYCDGDLGDLFDYIKKRGRHGLRFPFP

ERDAADAVKQILEAVAYLHENGIVHRDLKPENLLYATPAPDAPLKIADFGLSKIVEHQVLMKTVCGTPGYCAPEILRGCAYGP-EVDMWSVGIITYILLC
| .|.  ..||..|..|.|..||.||||||||.|  .      .||.||||....      .|.|||| |.|||.|    ||. ..|.||.|.| |..||
E-HARFYMYQICCALEYCHSHGIIHRDLKPENILLDE-----HIKICDFGLARQL------TTFCGTPWYMAPEVL---GYGKCKCDWWSCGCILYEMLC

GFEPFYDERGDQFMFRRILNCEYYFISPWWDEVSLNAKDLVKKLIVLDPKKRLTTFQALQ-------HPWV
|  ||.    .| ||..|.              |  |||...|. . ||.||.|  .|||       |||.
GYPPFP---QMQMMFKKIG--------------SPEAKDFIRKCLQKDPEKRPTA-EALQDEWDIKCHPWF
Kinase CaMK4.AA DCAMKL 42-296 38 6e-108 337.0 In-house 1-279 (279) Show / Hide 
Range on Protein: 42-296
Range on HMM: 1-279/279
Sequence Identity: 38% (108 aa)

FEVESELGRGATSIVYRCKQKGTQ-KPYALKV-----------------LKKTVDK---KIVRTEIGVLLRLSHPNIIKLKEIFETPTEISLVLELVTGG
...    | | ...|. |... |. . ||.|.                  .|   |   ...  |. .. ...||.||.| | ..|.|.. ||.|.|.||
YQIGRIIGDGNFAVVHECRHRETGDHKYAMKIRYQSTLQFSFPSKFFQQIDKRKCKGKEHMIDNEVSIMQKIKHPHIIQLYEHWDTETHYYLVMEYVQGG

ELFDRIVEKGYYSERDAADAVKQILEAVAYLHENGIVHRDLKPENLLYAT-PAPDAPLKIADFGLSKIVEH-QVLMKTVCGTPGYCAPEILRGCAYGPEV
 ||| |.| . ..|||||  . .. .|  |||| .|||||.||||||    .     || .|||| ..|.    .. |||||| |.|||||.   || .|
DLFDAITENTKFTERDAAIMMTCLCKALKYLHEMNIVHRDIKPENLLVCKHEDGEKSLKLCDFGLACHVNGDFGPLYTVCGTPTYVAPEILMETGYGCKV

DMWSVGIITYILLCGFEPFYDE-RGDQFMFRRILNCEYYFISPWWDEVSLNAKDLVKKLIVLDPKKRLTTFQALQHPWV
|.|..|.|.||||||| ||  . .  .  |  |. ... | .| ||..|. ||||.... . ||.|| |  | .|||||
DIWAAGVILYILLCGFPPFRSPDNDQEELFDQIMQGKFEFPMPYWDNISDSAKDLISHMLQVDPEKRYTAEQIMQHPWV
Kinase CaMK4.AA CDPK 42-296 41 6.9e-105 322.59 In-house 1-271 (271) Show / Hide 
Range on Protein: 42-296
Range on HMM: 1-271/271
Sequence Identity: 41% (114 aa)

FEVESELGRGATSIVYRCKQK-GTQKPY-ALKVLKKT-VDKKI----VRTEIGVLLRLSHPNIIKLKEIFETPTEISLVLE--LVTGGELFDRIVEKGYY
.  ...||.|. . |...|.| .|.    | |. .|  | .|     .  || .|  | ||||||. | ..    . .|.|  ..|||||||.|.|||..
YKIKKVLGKGHFGQVRKVKHKQKTNQERVAMKIIPKSRVKDKEQQQQFFNEIEILKQLDHPNIIKIYEFYQDEKNYYIVMETEYCTGGELFDYIIEKGHF

SERDAADAVKQILEAVAYLHENGIVHRDLKPENLLYATPAPDA----PLKIADFGLSKIVEHQ-----VLMKTVCGTPGYCAPEILRGCAYGPEVDMWSV
.|..||. ..||| ||.| |.|.||||||||||.|. .  .|.    ..|. |.|.||. ...       |.. |||| | |||.|..  |  ..| || 
TEKEAAYIMRQILSAVNYCHSNNIVHRDLKPENILFDSKKDDSWVIYNIKVIDWGTSKKFDQNQKIEDKKMSQRCGTPYYIAPEVLQKK-YNEKCDIWSC

GIITYILLCGFEPFYDERGDQFMFRRILNCEYYFISPWWDEVSLNAKDLVKKLIVLDPKKRLTTFQALQHPWV
|.| ||||||  ||| .  ||  .  . ...| |  | ||..| .||||..|... |||||..  |||||||.
GVILYILLCGYPPFYGKN-DQEIMEKVKKGKYSFEGPEWDHISDEAKDLIRKMLCYDPKKRMSAQQALQHPWF
Kinase CaMK4.AA PSK 42-296 41 8.1e-100 319.68 In-house 1-258 (258) Show / Hide 
Range on Protein: 42-296
Range on HMM: 1-258/258
Sequence Identity: 41% (108 aa)

FEVESELGRGATSIVYRCKQKGTQKPYALKVLKKT-VDKK-IVRTEIGVLLRLSHPNIIKLKEIFETPTEISLVLELVTGGELFDRIVEKGYYSERDAAD
...    |.|  | | |  .. |..||| |.. .   . . .   |  .| |..||.||.| |.|||   . .|.|. ||||.||||| || ..||||  
YDIKALIGKGSFSRVVRVEHRVTRQPYAIKMVETKCREGREFCENELNILRRVRHPYIIQLMEVFETQDRVYMVMEMATGGEMFDRIVAKGRFTERDATR

AVKQILEAVAYLHENGIVHRDLKPENLLYATPAPDAPLKIADFGL--SKIVEHQVLMKTVCGTPGYCAPEILRGCAYGPEVDMWSVGIITYILLCGFEPF
. . .|... |||  .| |||||||||||. | ... . | ||||  ..      .|||.|||| | |||.|    |   |||| ||.|.|||. |. ||
VLQMVLDGMRYLHALRITHRDLKPENLLYYHPGNESKIMITDFGLAYQRKKSNDWMMKTTCGTPEYIAPEVLLRKPYTQSVDMWAVGVIAYILMSGIMPF

YDERGDQFMFRRILNCEYYFISPWWDEVSLNAKDLVKKLIVLDPKKRLTTFQALQHPWV
 |.     ..|.||   | ..   | .||  ||| . || .... .|.|  ||..||||
DDDC-RTRLYRHILTGKYNYYGQPWPSVSHLAKDFIDKLLEINQGERMTASQAMKHPWV
Kinase CaMK4.AA MAPKAPK 43-296 34 1.1e-95 296.73 In-house 1-292 (292) Show / Hide 
Range on Protein: 43-296
Range on HMM: 1-292/292
Sequence Identity: 34% (102 aa)

EVESE-LGRGATSIVYRCKQKGTQKPYALKVLKKT--VDKKIVRTEIGVLLRLS-HPNIIKLKEIFET----PTEISLVLELVTGGELFDRIVE--KGYY
 . .| || |.   | .|..| |.. ||.|.|...     . .| |   . . . ||||... ..||      .   ||.|.  |||||..| .  ....
KLWKEVLGEGIYGKVQTCVHKRTGQEYAVKILEDQPGHSRQKARREVELHWHCQGHPNIVQIIDWFENMYQFDKCFYLVMECMEGGELFQHIQQRGHKHF

SERDAADAVKQILEAVAYLHENGIVHRDLKPENLLYATPAPDAPLKIADFGLSKI-------VEH--QVLMKTVCGTPGYCAPEILRGCA----YGPEVD
.|| |.  .|.| .||..||. .| ||||||||.|. ......|.|. |||. |         .   .. ..| |.|| |.|||..        |    |
TEREASQIMKDICSAVDFLHSMNIAHRDLKPENILCTDTNHNCPVKLCDFGFAKEIHLNHDCTTPITTPELMTPCYTPYYMAPEVVGAFKEAHTYDKSCD

MWSVGIITYILLCGFEPFYDERG------D---------QFMFRRILNCEYYFISPWWDEVSLNAKDLVKKLIVLDPKKRLTTFQALQHPWV
||| | | ||.|||. ||| . |      |         . ||.|| . .| | .. |...|  ||||..|| . ||..|||. | ..|||.
MWSLGVIMYIMLCGYPPFYSNCGDEDCSWDRGEACRDCQNMMFHRIQEGQYEFPDEEWSHISEEAKDLIRKLLRRDPTQRLTIEQVMNHPWI
Kinase CaMK4.AA CAMK-Unique 42-296 26 6e-92 303.81 In-house 1-363 (363) Show / Hide 
Range on Protein: 42-296
Range on HMM: 1-363/363
Sequence Identity: 26% (95 aa)

FEVESELGRGATSIVYRCKQKGTQKPYALKVLKK-TVDKKIVRT---------------------EIGVLLRLSHPNIIKLKEI----FETPT-------
 .    .| |. ..||.|. . | | .| |..|| |.  |.  .                     |........||||||| ..    |....       
YKMHRIIGHGNFGHVYECMDRETGKKWACKMVKKQTHGNKKQKQQRNFDLRYKITEKRRDMKLKREHQIWKMVDHPNIIKLYDWNNPIFCDRKYPLCDLI

--------EISLVLELVTGGELFDRIVE--------------------KGYYSE--RDAADAVKQILEAVAYLHENGIVHRDLKPENLLYATPAP-----
        .. .|.|...||.||| |..                    .|..||  .|..  . ..|.||||.|...|||||||.||... .. .     
IKTPRALPYMYIVMEYCQGGDLFDWIQKWDEFYFNFIIKFDFNILKRCQGHFSERCWDTCFIMQCLLSAVAYMHSQDIVHRDLKLENIMVCYSFKDNNHH

--------DAPLKIADFGLSKIVE-HQVL--MKTVCGTPGYCAP--------------EILRGCAYGPEV----DMWSVGIITYILLCGFEPFYDERGDQ
        .  .|..||||.. ..  ..   |.|.|||| |.||              |.. .  |.  .    | || | |.|..|||  ||. |  | 
RDFPYDWSNWHIKLCDFGLCCHYNHNKMCHMMQTMCGTPCYMAPEIVFCKNYQEMTRDEVINMQCYDQQCSPASDIWSLGVIMYYMLCGCPPFDCECEDR

-------FMFRRILNCEY-YFISPWWDE---VSLNAKDLVKKLIVLDPKKRLTTFQALQHPWV
         |..|. ..| .| ...|.    .| .|||.||.. ..||..|..  ..|.|.|.
DYENHDKEIFECICKGDYCNFDWKMWHGPDYISQEAKDFVKCCMTVDPDHRWSAKELLEHQWI
Kinase CaMK4.AA CAMKL 42-296 34 4.5e-91 290.87 In-house 1-297 (297) Show / Hide 
Range on Protein: 42-296
Range on HMM: 1-297/297
Sequence Identity: 34% (103 aa)

FEVESELGRGATSIVYRCKQ-KGTQKPYALKVLKKTVDKKI-----------------VRTEIGVLLRLS---HPNIIKLKEIFETPTE------ISLVL
.... .||.|. . |  ..  . |.. .| |...|   ...                 .| ||  . .|.   ||||||| |..|||.       | ||.
YRIGKTLGKGSFGKVKLATHIRTTGEKVAIKIIDKKKIWNDPWMKKNKCGQKHESDMRIRREIQIMKMLNIGKHPNIIKLYEVIETPEHDIETKKIYLVM

ELVTGGE--LFDRIVEKGY----YSERDAADAVKQILEAVAYLHENGIVHRDLKPENLLYATPAPDAPLKIADFGLSKIVE-H----QVLMKTVCGTPGY
|.. |||  |||.||..|.     .|..|    .||..||.|.|..||||||.||||.|         .||.|||.| . . .      ..|| ||.| |
EYCSGGEMDLFDYIVKHGHRRGRMPEHEARRYFRQIVSAVNYCHSHGIVHRDIKPENILLDENGNN-NIKIIDFGFSNMYRPCIFGPGQKLKTFCGSPPY

CAPEILRG--C-AYGPEVDMWSVGIITYILLCGFEPFYDERG------DQFMFRRILNCEYYFISPWWDEVSLNAKDLVKKLIVLDPKKRLTTFQALQHP
.||||. |     .||.||.|| |.| | ..||  || |.        ..  .... .|  |.. | | .||  ..|| .|. . .|.|| |  | ..||
MAPEIFQGNNKPYDGPKVDIWSCGVILYAMVCGYLPFDDDTYNKQGKDNI-YLYWKIMCG-YYP-PIWYHVS-DCRDLIRKMLQVNPEKRPTIHQIMNHP

WV
|.
WM
Kinase CaMK4.AA RSK 42-296 32 1.3e-89 303.99 In-house 1-278 (278) Show / Hide 
Range on Protein: 42-296
Range on HMM: 1-278/278
Sequence Identity: 32% (92 aa)

FEVESELGRGATSIVYRCKQKGTQKPYALKVLKK-TVDKKIV-----RTEIGVLLRLS-HPNIIKLKEIFETPTEISLVLELVTGGELFDRIVEKGY---
 .|  ..| |. ... .| .. |.. || ||||| ..... .     .||. .|.|   ||.|..|.. |.|.... |..|.. |||||... ....   
LKVLGQGGYGKVFLCRKCTHHDTGQIYAMKVLKKAKIVQRQKDTRHTMTERNILERCQQHPFIVTLHYAFQTEGKLYLIMEYCRGGELFTHLQKEKHFGC

YSERDAADAVKQILEAVAYLHENGIVHRDLKPENLLYATPAPD-APLKIADFGLSKI--VEHQVLMKTVCGTPGYCAPEILR----GCAYGPEVDMWSVG
 ||..|..   .|  || .||. ||.|||||||| ||.    . . .|. |||..|.   .|  ...| |.|  |.|||.|.    .....  .| || |
FSEDEACFYMAEIVLAVEHLHQQGIIHRDLKPENILYDDES-NEGHIKLTDFGFCKQFRCDHNQWTMTFCYTIEYMAPEMLKRANQQGGHDKACDWWSLG

IITYILLCGFEPFYDERGD---QFMFRRILNCEYYFISPWWDEVSLNAKDLVKKLIVLDPKKRLT-----TFQALQHPWV
.. | .| |. ||.   .|   .  ..||..... . .| |...| .||||..|.   ||.|||.     . . .|||| 
VLMYEMLTGCPPFQG-PNDNNRKEIMKRIQKGKFSLTMPNWQYLSQEAKDLIRKMLHRDPHKRLGCGPQDAEEIKQHPWF
Kinase CaMK4.AA TyrKc 42-295 21 2.4e-14 9.18 SMART 1-280 (280) Show / Hide 
Range on Protein: 42-295
Range on HMM: 1-280/280
Sequence Identity: 21% (62 aa)

FEVESELGRGATSIVYRCKQKGTQKPYALKVLKKTVDKKIVRTEIGVLLRL--SHPNIIKLKEIFETP-------TEISLVLELVTGGELFDRIVEKGY-
 . . .||.||  .||... |    . | |.||.   ..  . |. .. .|  .||||..|  .  ..         . .|.|.. .| | |.. ...  
ITLGKKLGEGAFGEVYKGTWK---IQVAVKMLKEDA-REDFMREARIMCKLGGHHPNIVRLYGVCTQQGRNFMYIEPLMIVMEYMPHGDLKDYLRKHRPK

YSERDAADAVKQILEAVAYLHENGIVHRDLKPENLLYATPAPDAPLKIADFGLSKIVEHQ--------VLMKTV-CGTPG-----YCAPEILRGCAYGPE
 . .|  .   || .  .|||.....||||   | |.. .      ||.|||||. ...         . .|.   |. .      .||| .. . . ..
LCMKDLLSFCWQIACGMEYLHSKNCIHRDLAARNCLVGENH---TVKISDFGLSRDIYDDDQQGESKDYYRKKEHKGGKTMLPIRWMAPECINYGKFTTK

VDMWSVGIITY-ILLCGFEPFYDE----RGDQFMFRRILNCEYYFISPWWDE--------VSLNAKDLVKKLIVLDPKKRLTTFQALQHPW
 | || |.  . |.  | .| ...      .| ..... . ..  . |   .         .    .. |.    ||..|  ||... . .
SDVWSFGVCMWEIFTYGQQPYPGMIQQMMSNQEVIEYVKQGYRMPQPP---NDYPMSFVCCPDEMYQIMKQCWHEDPEDRP-TFSEIHECF
Kinase CaMK4.AA Pkinase_Tyr 42-190 26 1.3e-07 26.38 Pfam 1-163 (270) Show / Hide 
Range on Protein: 42-190
Range on HMM: 1-163/270
Sequence Identity: 26% (45 aa)

FEVESELGRGATSIVYRCKQK----GTQKPYALKVLKKTVDKK------IVRTEIGVLLRL-SHPNIIKLKEIFE--TPT-EISLVLELVTGGELFDRIV
 .   .||.||   ||... |    .|. | | |.|| . ...        | |. ..  | .||||..|  .        .| .|.|.. .| | |   
ITFGKKLGEGAFGEVYKGTWKGDPDNTKIPVAVKMLKEGAMHEQNCREDFMR-EAKIMKQLGHHPNIVRLYGVCTDQGEPNQIYIVMEYMPHGDLLDYLR

E----KGYYSERDAADAVKQILEAVAYLHENGIVHRDLKPENLLYATPAPDAPLKIADFGLSKIVEH
.    |.  .  |  .   || .. .||......||||   | | .    .   ||.||||.. ...
KHREDKQPLTMKDLLQMCWQIAKGMEYLESKNCIHRDLAARNCLVTE---NNVVKICDFGLARDIYN