Gene CYGD (Mouse)

CYGD

Species: Mouse
Alias: CYGD, Gucy2e
External Links: MGI , Entrez Gene , Refseq cDNA , Refseq Protein , Phosphosite , iHOP
Annotation:

Classification

Group: RGC
Family: RGC

Sequence

Name Sequence Type Origin Length Description Download
CYGD.kin_dom Protein Kinase Domain Sugen global kinase HMM prediction 273 Kinase domain by global Sugen HMM Fasta, JSON
CYGD.AA Protein Sugen 1108 None Fasta, JSON
CYGD.NA RNA Sugen 8331 None Fasta, JSON

Protein domain

Protein domains of CYGD.AA. The domains are annotated by HMM profiles from Pfam and SMART, as well as in-house data which includes HMMs of each individual kinase group, family and subfamily. Here is domain list in details, including sequence identity, significance and alignment. In particular, you can find can find the best hit kinase group/family/subfamily, which is helpful to understand the relationship between kinases.Kinase domain and best hit kinase group/family/subfamily are highlighted in red and blue. Visualized by pviz.

Usage: Zoom in selected region by dragging mouse and zoom out by double-clicking.

Show/hide domain list
Domain Protein name Domain Name Range Identity (%) Significance Score Profile Source Profile Range (length) Alignment
ANF_receptor CYGD.AA ANF_receptor 75-411 17 3e-55 194.65 Pfam 1-364 (364) Show / Hide 
Range on Protein: 75-411
Range on HMM: 1-364/364
Sequence Identity: 17% (68 aa)

RPDLAARLAANRLNRDFA-LDGGPRFEVALLPE----PCLTPGSLGAVSSALSRVSGLVGPVNPAACRPAELLAQEAGVALVPWGCPGTRAAGT------
.. .|.|.|  ..|.|   |. | ....  . .     | ....... . . ..| ...||.....|.|.  .|..... .. |||. ..   .      
QCAPAMRMAIEDINADPGILLPGITLGYHDDDCCYCSDC-QAVAAADCCWH-KGVVAIIGPSCSYVCIPVARIANHWNIPMISWGCTCPCLTDKAKNRYP

----TAPAVTPA-ADALYVLLRA-FRWARVALITAPQDL--WVEA---GRALSTALRARGLPVALV--TSMETSDRSGAREALGRIRD--GPRVRVVIMV
    |.|  |   ..|.  ...  |.|..||.|   .|   |..     .|. ..||..|... ..  .|| ... . ....| .|.|  ....||..| 
YFFRTVPSDTYQYGWAMVDIIQHHFGWKWVAVIYDDDDYYYWRGGCYFMEAFQDELREHGGNCVYYAYVSMVIPWDDDFMDYLKKIKDIIKMKARVIVMC

MHSVLLGGEEQRYLLEAAEELALTDGSLVFLPFDTLHYALSPGPEALAAFVNSSQLRRAHDAVLTLTRRCPPGGSVQDSLRRAQEHQELPLDLNLKQVSP
... ..| ..|| ....|.|| ...|. |... |......  .  .  . ..   .|.| ..||..| . |   ..|. ..|...        .  ....
CYPDDMG-LLQRQIMQQAHELGMMSGGYVWIYTDWWMHSYDMQ-WWYDDDMDNDKFREAMKGVLGFTMH-P-SPEFQEFMQRWKK--------TDTEMNY

LFGTIYDAVFLLAGGVKRARTAVGGGWVSG--------ASVARQVRE-AQVSGFCGVLGRTE------EPSFVLLDTD
 ....|||| |.| ........ ...|..|        ...... ..  .  |..| .   .       ........|
YAAYAYDAVYLYAHALHNMLRCDPNHWNGGCDIMKWHGWQLLHYMWNKVNFEGVTGDVQFDDNGGRRPDYMYWIMNWD
Kinase CYGD.AA RGC 559-810 34 2.6e-116 392.73 In-house 1-300 (300) Show / Hide 
Range on Protein: 559-810
Range on HMM: 1-300/300
Sequence Identity: 34% (105 aa)

EGDWVWLKKFPGE---HHMAIRPATKTAFSKLRELRHENVALYLGLFLAGTADSPATPGEGILAVVSEHCARGSLHDLLAQREIKLDWMFKSSLLLDLIK
||||||.||..     .|  ....... . ..|.|.|.|.. ..|... ......    .| ...|.|.|.||||.|.|....||.|||||.|.. |..|
EGDWVWIKKHNQRNLFRHWDFTRSMMRELKQMRQLQHDNLNKFIGMCIDPPMEYH----PGNMCIVWEYCSRGSLQDILENDDIKMDWMFKYSFIRDIVK

GMRYLHHRGV-AHGRLKSRNCVVDGRFVLKVTDHGHG-----RLLEA-------------QRVLPEPPSAEDQLWTAPELLR----DPSLE-----RRGT
||.||||. .  ||.|||.|||||.|.|.|.||.|..     .. .              ||  .| |. ...||||||.||    ... .     .|||
GMQYLHHSPIRYHGNLKSWNCVVDSRWVVKITDFGLNNPLCHWFKHGQINPPCKSDDKSWQRQHDEHPYYKKMLWTAPEHLREWRMPHQWGPHRQTQRGT

LAGDVFSLAIIMQEVVCRST-----PYAML----ELTPEEVIQRVRSPPP-----LCRPLVSMD------QAPMECIQLMTQCWAEHPELRPS-MDLTFD
 .|||.|..|||.|...|.      |..|.    ||.|.|.|..|. ||.     ..||....|      ........|| .|||| || ||. .|  ..
QKGDVYSFGIIMYEIITRKGPWDLEPFCMWPGEYELSPMEIIEEVKYPPKKGGQKPFRPSIHEDEEGHMIECNPCLLHLMRDCWAEDPEERPDMFDQIRK

LFKS
..|.
QLKT
Kinase CYGD.AA RGC 559-810 34 2.6e-116 392.73 In-house 1-300 (300) Show / Hide 
Range on Protein: 559-810
Range on HMM: 1-300/300
Sequence Identity: 34% (105 aa)

EGDWVWLKKFPGE---HHMAIRPATKTAFSKLRELRHENVALYLGLFLAGTADSPATPGEGILAVVSEHCARGSLHDLLAQREIKLDWMFKSSLLLDLIK
||||||.||..     .|  ....... . ..|.|.|.|.. ..|... ......    .| ...|.|.|.||||.|.|....||.|||||.|.. |..|
EGDWVWIKKHNQRNLFRHWDFTRSMMRELKQMRQLQHDNLNKFIGMCIDPPMEYH----PGNMCIVWEYCSRGSLQDILENDDIKMDWMFKYSFIRDIVK

GMRYLHHRGV-AHGRLKSRNCVVDGRFVLKVTDHGHG-----RLLEA-------------QRVLPEPPSAEDQLWTAPELLR----DPSLE-----RRGT
||.||||. .  ||.|||.|||||.|.|.|.||.|..     .. .              ||  .| |. ...||||||.||    ... .     .|||
GMQYLHHSPIRYHGNLKSWNCVVDSRWVVKITDFGLNNPLCHWFKHGQINPPCKSDDKSWQRQHDEHPYYKKMLWTAPEHLREWRMPHQWGPHRQTQRGT

LAGDVFSLAIIMQEVVCRST-----PYAML----ELTPEEVIQRVRSPPP-----LCRPLVSMD------QAPMECIQLMTQCWAEHPELRPS-MDLTFD
 .|||.|..|||.|...|.      |..|.    ||.|.|.|..|. ||.     ..||....|      ........|| .|||| || ||. .|  ..
QKGDVYSFGIIMYEIITRKGPWDLEPFCMWPGEYELSPMEIIEEVKYPPKKGGQKPFRPSIHEDEEGHMIECNPCLLHLMRDCWAEDPEERPDMFDQIRK

LFKS
..|.
QLKT
Kinase CYGD.AA TK 585-808 15 9.3e-22 69.04 In-house 93-486 (486) Show / Hide 
Range on Protein: 585-808
Range on HMM: 93-486/486
Sequence Identity: 15% (62 aa)

SKLRE--LRHENVALYLGLFLAGTADSPAT--PGEGILAVVSEHCARGS----LHDLLAQREIK------------------------------------
.....  ..|.|.   .|  . |   .. .   ... . .| |... |.    |.| | ..  |                                    
KMMCHSLGHHPNIVRLYGVCTQGEPKPCFEVVVHQEPWMIVMEYMPHGDMDGSLRDYLRKCRPKFQHEQDCPDNQHNKYPPSKLHHCMKGDITYSHESNS

---------------------------------------LDWMFKSSLLLDLIKGMRYLHHR------GVAHGRLKSRNCVVDGRFV-----------LK
                                       |.   .    ... .||.||| .      .. |. |  ||| |. . |            |
PCPEEQDYDDDLIKDHPPPLTTKDLLQMAWQWCLTCKHQLTMHQLL-MCWQIACGMEYLHSKNCEFIQNFVHRDLAARNCLVGENNVCKWHFDGCGPVCK

VTDHG--------HGRLL---EAQRVLPEPPSA-------------------EDQL---WTAPELLRDPSL-----ERRGTLAGDVFSLAIIMQEVVCRS
..| |        . | .   .  ..  ..  .                    ..|   |.||| |.|        ... | . ||.|. . | |.. . 
IADFGLSRQGSGVLARDIYSDDDYYRKSSYGTGRPMWPFEDDPWQDYYRQQSGGKLPIRWMAPECLNDRVFSEAEKYGKFTTKSDVWSFGVLMWEIFTYG

-TPYA--ML-------ELTPEEVIQRVRS-------------------PPPLCRPLV--SMDQAP-----MECIQLMTQCWAEHPELRPSMDLTFDLF
 .||.  |        . ...||....|.                   .||.| . .   | . |      |  .||.|||.. || ||...   . .
QEPYYGGMSNQDVWKDG-DNQEVMEYLRRGGRLCRSGLNEVGYRMRMPQPPHCPDWMRYRM-H-PPHCPPEEYYDLMQQCWHYDPEDRPTFSQLHEQL
Kinase CYGD.AA TKL-Unique 621-802 26 9.4e-18 59.32 In-house 78-284 (290) Show / Hide 
Range on Protein: 621-802
Range on HMM: 78-284/290
Sequence Identity: 26% (57 aa)

VSEHCARGSLHDLLA---------QREIKLDWMFKSSLLLDLIKGMRYLHHRG--VAHGRLKSRNCVVDGR-----FVLKVTDHGHGRLLE--AQRVLPE
|.| | .|||.|.|.          ...||..  . .. .|  .|| ||||..  ..|. |||.|  || .     .  |. | |  ...    .  . |
VMEYCPGGSLYDVLHQNNNNNNNNNNNCKLNMQQRVKMAIDIAQGMYYLHHCEPPIIHRDLKSSNFLVDNNSNIAEWNIKICDFGLSKFNSKINKMTNNE

P-----PSAE-DQLWTAPELLRDPSLERRGTLAGDVFSLAIIMQEVVCRST------PYAMLELTPEEVIQRVRSPPPLCRPLVSMDQAPMECIQLMTQC
.     .. .   .| |||.||..   .  .   ||.| .|.. | . |        ||   ....|.... |..     || ....  | |   |..||
HKGTRNQTRCGSFRWMAPEVLRMNFCQY--SEKSDVYSFGIVLWEIATRKITKTYKKPY--QGMDQEQWCEMVHYMEENYRPPIPNH-CPKEYRDLIQQC

WAEHPELRPSMD
|.  |. ||| |
WHHDPSQRPSFD
Kinase CYGD.AA TKL 587-687 25 1.4e-14 48.96 In-house 79-197 (364) Show / Hide 
Range on Protein: 587-687
Range on HMM: 79-197/364
Sequence Identity: 25% (33 aa)

LRELRHENVALYLGLFLAGTAD-SPATP--GEGILAVVSEHCARGS-LHDLLAQREIKLDWMFKSSLLLDLIKGMRYLHH--------RGVAHGRLKSRN
.. |||.|. ...|  .... .     |  ..| |. | | | .|| ||.|.        |  . .. ||  .|| |||         ....|  |||.|
MSRLRHPNIVQFMGYCCCPPCGCVCMHPVGPWGQLCIVMEYCPGGSLLHYLH--------WHQRCRWALDIARGMNYLHSMNPKWCTKPPIIHRDLKSKN

CVVDGRFV--------------LKVTD
. ||  .               .|..|
ILVDENWTNVSNYMYNPNADWCCKICD
Kinase CYGD.AA Src-Echino1 656-808 29 4.3e-14 44.82 In-house 108-252 (252) Show / Hide 
Range on Protein: 656-808
Range on HMM: 108-252/252
Sequence Identity: 29% (45 aa)

GMRYLHHRGVAHGRLKSRNCVVDGRFVLKVTDHGHGRLLEAQRVLPEPPSAEDQLWTAPELLRDPSLERRGTLAGDVFSLAIIMQEVVC-RSTPYAMLEL
|| ||  . | |  |  || .|.   | |. | |  |...      .        |||||      |  | |.  ||.|  |.| |.|     ||   ..
GMDYLGSKNVVHRDLAARNVLVGKGNVCKIADFGLARMMQKDVYCGKQGAKLPIKWTAPEAA----LYGRFTIKSDVWSFGILMTEMVTFGRYPYP--GM

TPEEVIQRVRSPPPLCRPLVSMDQAPMECIQL-MTQCWAEHPELRPSMDLTFDLF
.  ||...|     .   .  |.. |    .. | .||   |  || ..   | |
MNREVLDQVD----RGYRMPKMHHCPDSLYMMCMMKCWHKDPQQRPTFEFLHDFF
Kinase CYGD.AA Pkinase 587-811 16 4.9e-14 50.7 Pfam 54-293 (293) Show / Hide 
Range on Protein: 587-811
Range on HMM: 54-293/293
Sequence Identity: 16% (43 aa)

LRELRHENVALYLGLFLAGTADSPATPGEGILAVVSEHCARG----SLHDLLA-QREIKL--DWMFKSSLLLDLIKGMRYLHHRGVAHGRLKSRNCVVDG
...|.|.|.  ... |            .. . .| |.|  |    .|.|..  .|. ..  ..    . .. ...|. |.| .|. |  ||. |. .| 
MKRLNHPNIVRLYDWFED----------KDHIYMVMEYCEGGLYVMDLFDYISTWRHGCFYFSEWECKFYMYQILRGLEYCHSMGIIHRDLKPENILIDN

RFVL----KVTDHGHGRLLEAQRVLPEPPSAEDQ----LWTAPELLRDPSLERRGTLAGDVFSLAIIMQEVVCRSTPYAML----ELTPEEVIQRVRS--
. ..    |..| |  ....    .   . . .      . |||..|     .  . . |..|. .|. |..|. .|.       .... ..|.|...  
NGHIDACVKICDFGLAKQFD----Y-NNS-MTTFCGTPWYMAPEVIR---GGQYYGPKVDMWSCGCILYEMLCGRPPFPGHCWHDNHDQMQMICRIMGPP

----PPPLCRPL-----------VSMDQAPMECIQLMTQCWAEHPELRPSMDLTFDLFKS--I
     | .|..            .  . .. ||..... |..  |. ||.     .....  .
LHFDWPWWCSISYFFFRHWHFHWTF-HNWSEECKDFIKWCLCKDPKKRPT---AEQILQHPWF
Kinase CYGD.AA TESK 615-677 42 8e-14 39.59 In-house 65-127 (292) Show / Hide 
Range on Protein: 615-677
Range on HMM: 65-127/292
Sequence Identity: 42% (27 aa)

EGILAVVSEHCARGSLHDLLAQREIKLDWMFKSSLLLDLIKGMRYLHHRGVAHGRLKSRNCVV
.| |  . |    |.| .|||. |. | |  |  | .|  .||.||| .|| |  | |.|| |
QGQLHALTEYINGGCLEQLLADSELHLSWTQKIHLAYDIARGMSYLHSKGVFHRDLTSKNCLV
Kinase CYGD.AA TKL 711-808 22 6.8e-13 42.78 In-house 239-364 (364) Show / Hide 
Range on Protein: 711-808
Range on HMM: 239-364/364
Sequence Identity: 22% (28 aa)

WTAPELLRDPSL------------ERRGTLAGDVFSLAIIMQEVVCRSTPYAMLELTP-----------EEVIQRVRSPPPLCRPL-----VSMDQAPME
| |||.||.               ..  . . ||.| .|.. |...| .||. .   |           . |... . ||.  ...     .  ...| .
WMAPEVLRGQMNYTEKVGIDEFCKGFEYSEKCDVYSFGIVLWEILTRCRPYYDYPYMPMIFQDPFEEMFMMVCDKGLRPPIPPIWQNHHKMCPCPDCPPS

CIQLMTQCWAEHPELRPSMDLTFDLF
 ..||..||.. || |||..   . .
MKKLMQDCWDHDPEKRPSFQEILKRL
S_TKc CYGD.AA S_TKc 547-808 15 3.3e-11 -12.47 SMART 13-231 (231) Show / Hide 
Range on Protein: 547-808
Range on HMM: 13-231/231
Sequence Identity: 15% (45 aa)

SQPQESTNVGLYEGDWVWLKKFPGEHHMAIRPATKTAFSKLRELRHENVALYLGLFLAGTADSPATPGEGILAVVSEHCAR--GSLHDLLAQREIK----
..    ....   |  | .|. .          ..   . |.. .|.|.  ... |             . | .| |.|    |.|.|.. .|  .    
GKVYKCRHKK--TGRIVAIKIIK--------EHIRREIQILKK-HHPNIVKLYDVFQD-----------DHLYMVMEYCDGDLGDLFDYIKKRGRHGLRF

-LDWMFKSSLLLDLIKGMRYLHHRGVAHGRLKSRNCVVDGRFVLKVTDHGHGRLLEAQRVLPEPPSAEDQL-----WTAPELLRDPSLERRGTL-AGDVF
 ..     ...  ..... |.| .|. |  ||  |  .|   ..|..| |  |.|             . .     . |||.|         .  . |. 
PFPE-HARFYMYQICCALEYCHSHGIIHRDLKPENILLDE--HIKICDFGLARQL-------------TTFCGTPWYMAPEVL-------GYGKCKCDWW

SLAIIMQEVVCRSTPYAMLELTPEEVIQRVRSPPPLCRPLVSMDQAPMECIQLMTQCWAEHPELRPSMDLTFD---------LF
|. .|. | .|. .|.     ..........               . |..... .|.   || ||.    .           |
SCGCILYEMLCGYPPFP----QMQMMFKKIG---------------SPEAKDFIRKCLQKDPEKRPTA-EALQDEWDIKCHPWF
TyrKc CYGD.AA TyrKc 558-808 23 2.9e-10 -56.6 SMART 16-280 (280) Show / Hide 
Range on Protein: 558-808
Range on HMM: 16-280/280
Sequence Identity: 23% (67 aa)

YEGDWVWL----KKFPGEHHMAIRPATKTAFSK----LREL--RHENVALYLGLFLAGTADSPATPGE------GILAVVSEHCARGSLHDLLAQREIKL
|.| |  .    |.   ..        . .| .    ...|  .|.|.   .|          .| ..      . | .| |... |.|.| |  .. ||
YKGTWK-IQVAVKMLKEDA--------REDFMREARIMCKLGGHHPNIVRLYGV---------CTQQGRNFMYIEPLMIVMEYMPHGDLKDYLRKHRPKL

DWMFKSSLLLDLIKGMRYLHHRGVAHGRLKSRNCVVDGRFVLKVTDHGHGRLLEAQ-------RVLPE--PPSAEDQL---WTAPELLRDPSLERRGTLA
 .  . |  ..  .||.|||.... |  |  ||| |. ... |..| |  | ..          .       .. . |   |.||| .     ... | .
CMKDLLSFCWQIACGMEYLHSKNCIHRDLAARNCLVGENHTVKISDFGLSRDIYDDDQQGESKDYYRKKEHKGGKTMLPIRWMAPECI----NYGKFTTK

GDVFSLAIIMQEVVCR-STPYA-MLE--LTPEEVIQRVRSPPPLCRPLV-----SMDQAPMECIQLMTQCWAEHPELRPSMDLTFDLF
 ||.|  . | |.  .  .||  | .  ....|||..|..   . .|       .   .| |  |.|.|||.| || ||..    ..|
SDVWSFGVCMWEIFTYGQQPYPGMIQQMMSNQEVIEYVKQGYRMPQPPNDYPMSF-VCCPDEMYQIMKQCWHEDPEDRPTFSEIHECF
Kinase CYGD.AA Dicty5 621-697 25 3.1e-10 31.43 In-house 77-157 (260) Show / Hide 
Range on Protein: 621-697
Range on HMM: 77-157/260
Sequence Identity: 25% (21 aa)

VSEHCARGSLHDLLAQREI----KLDWMFKSSLLLDLIKGMRYLHHRGVAHGRLKSRNCVVDGRFVLKVTDHGHGRLLEAQ
|.| | .||| ..| ...      . .  . .. .|  ..||.||  .. |  ||| |  .  ..  |. | |  |  ...
VTEYCHNGSLFNYLNDQRKTTGQPIAYFQQLHMAIDIAQSMRHLHSMNIIHRDLKSMNFLITENWKIKIIDFGTSRFVDNR
Kinase CYGD.AA DRK 620-689 37 8.1e-10 29.47 In-house 74-145 (258) Show / Hide 
Range on Protein: 620-689
Range on HMM: 74-145/258
Sequence Identity: 37% (27 aa)

VVSEHCARGSLHDLLAQREIKLDWMFKSSLLLDLIKGMRYLHHRG--VAHGRLKSRNCVVDGRFVLKVTDHG
.. |   ||||   |    |..||    .. .|  ||| ||| .   . |  ||| |  ||  .  || | |
ICMEYMPRGSLYNILHDESIEMDWPLMKQMMFDCAKGMIYLHCCNPIIIHRDLKSHNLLVDEHWQVKVADFG
Kinase CYGD.AA RTKB 778-808 32 3.6e-07 20.24 In-house 234-264 (264) Show / Hide 
Range on Protein: 778-808
Range on HMM: 234-264/264
Sequence Identity: 32% (10 aa)

QAPMECIQLMTQCWAEHPELRPSMDLTFDLF
|.| .   .|..||..... ||. |   |.|
QMPQAADHIMQMCWQMEAQHRPDFDELVDAF
Kinase CYGD.AA Pkinase_Tyr 587-687 23 4e-06 21.53 Pfam 57-154 (270) Show / Hide 
Range on Protein: 587-687
Range on HMM: 57-154/270
Sequence Identity: 23% (25 aa)

LREL-RHENVALYLGLFLAGTADSPATPGEGI--LAVVSEHCARGSLHDLLAQR---EIKLDWMFKSSLLLDLIKGMRYLHHRGVAHGRLKSRNCVVDGR
...| .|.|.  ..|  .         . ..   . .| |... |.|.| | ..   . .|.   . .  ..  ||| ||. ..  |  |  ||| |.  
MKQLGHHPNIVRLYGVCT---------DQGEPNQIYIVMEYMPHGDLLDYLRKHREDKQPLTMKDLLQMCWQIAKGMEYLESKNCIHRDLAARNCLVTEN

FVLKVTD
.| |..|
NVVKICD
Kinase CYGD.AA DRK 711-750 47 1.5e-05 14.77 In-house 168-203 (258) Show / Hide 
Range on Protein: 711-750
Range on HMM: 168-203/258
Sequence Identity: 47% (19 aa)

WTAPELLRDPSLERRGTLAGDVFSLAIIMQEVVCRSTPYA
||||| ||    . | |   ||.| ||.  |.| |  ||.
WTAPEVLR----NQRYTEKADVYSFAIVLWECVTRQDPYF
Kinase CYGD.AA DRK 784-810 44 1.8e-05 14.51 In-house 232-258 (258) Show / Hide 
Range on Protein: 784-810
Range on HMM: 232-258/258
Sequence Identity: 44% (12 aa)

IQLMTQCWAEHPELRPSMDLTFDLFKS
||||. || | |  ||||.       .
IQLMNDCWNEDPQHRPSMQECLERLEA
Kinase CYGD.AA RTKB 651-695 33 2.4e-05 14.02 In-house 116-160 (264) Show / Hide 
Range on Protein: 651-695
Range on HMM: 116-160/264
Sequence Identity: 33% (15 aa)

LDLIKGMRYLHHRGVAHGRLKSRNCVVDGRFVLKVTDHGHGRLLE
..  .|| .|| ..| |. |  || .||  .  |. |.|  | ..
HQIACGMAFLHQHNVIHRDLCARNVLVDQQLHCKICDFGMAREID
Kinase CYGD.AA Dicty5 786-812 37 0.001095 8.56 In-house 234-260 (260) Show / Hide 
Range on Protein: 786-812
Range on HMM: 234-260/260
Sequence Identity: 37% (10 aa)

LMTQCWAEHPELRPSMDLTFDLFKSIN
|   || . | .|||     . |.|| 
LIKKCWQQKPHNRPSFKEICKYFESII
Kinase CYGD.AA Pkinase_Tyr 711-801 27 0.001681 12.48 Pfam 180-263 (270) Show / Hide 
Range on Protein: 711-801
Range on HMM: 180-263/270
Sequence Identity: 27% (26 aa)

WTAPELLRDPSLERRGTLAGDVFSLAIIMQEVVCRS-TP-YAMLELTPEEVIQRV-RSPPPLCRPLVSMDQAPMECIQLMTQCWAEHPELRPSM
|.||| ...       | . || |  . | |.. .  .| |. .  ..|||.... ..     . .   . .| |  .||.|||.. || ||..
WMAPECINYGK----FTTKSDVWSFGVLMWEIFTYGEQPTYPGM--SNEEVYEYIYED----GYRMPCPENCPDEIYDLMKQCWHYDPEDRPTF
Kinase CYGD.AA TESK 711-745 37 0.004913 4.92 In-house 202-232 (292) Show / Hide 
Range on Protein: 711-745
Range on HMM: 202-232/292
Sequence Identity: 37% (13 aa)

WTAPELLRDPSLERRGTLAGDVFSLAIIMQEVVCR
| ||| ||.   ...     ||||  |.. |.. |
WMAPEVLRGEWYDEK----ADVFSFGIVLCEIIAR
Kinase CYGD.AA Dicty5 731-749 42 0.032677 3.41 In-house 185-203 (260) Show / Hide 
Range on Protein: 731-749
Range on HMM: 185-203/260
Sequence Identity: 42% (8 aa)

DVFSLAIIMQEVVCRSTPY
||.| .|.  |.  | .||
DVYSFGIVLWEMFTRKEPY
CYCc CYGD.AA CYCc 847-1050 47 4.2e-106 359.7 SMART 1-231 (231) Show / Hide 
Range on Protein: 847-1050
Range on HMM: 1-231/231
Sequence Identity: 47% (110 aa)

QEKQKTDRLLTQMLPPSVAEALKMG-TSVEPEYFEEVTLYFSDIVGFTTISAMSEPIEVVDLLNDLYTLFDAIIGAHD-----VYKVETIGDAYMVASGL
 ||||.||||.||||..||. || | ..|.|. ...||..|.||||||.......|..||..|||.|| || ||. |.     .||||||||||||.||.
MEKQKNDRLLCQMLPRHVANQLKQGRHPVWPPCYDCVTILFTDIVGFTNLCSWCTPMQVVNMLNDHYTRFDRIIDRHGCYHNYCYKVETIGDAYMVVSGC

PQRNG-------------------QRHAAEIANMSLDILSAVGSFRMRHM----PEVPVRIRIGLHSGPCVAGVVGLTMPRYCLFGDTVNTASRMESTGL
| ||.                   ..|| .||...||.......| ..|     |. |.|.|||.|.||.|.||||..|||||.||||||.||||||||.
PTRNEHNQCQCLHHWWTWCFWCFHWQHAQWIADWALDMVECMKTFHVQHHMGELPWNPLRMRIGIHTGPVVCGVVGIRMPRYCYFGDTVNMASRMESTGD

PYRIHVNMSTVRILRALDQGFQMECRGRTELKG
| .|||  .| ..|  || .|.. ..|. |...
PGQIHVSEETYWCL-CLD-QFERRRCGQFEFEP
Guanylate_cyc CYGD.AA Guanylate_cyc 874-1061 42 1.6e-91 315.15 Pfam 1-214 (214) Show / Hide 
Range on Protein: 874-1061
Range on HMM: 1-214/214
Sequence Identity: 42% (91 aa)

VEPEYFEEVTLYFSDIVGFTTISAMSE----PIEVVDLLNDLYTLFDAIIGAH--DVYKVETIGDAYMVASGLPQR-----NGQRHAAEIANMSLDILSA
|... ...||..|.|||||| ... ..    |...|..|||.|| || ....|  ..|||.||||.||..||||..     ..  ||. .|.|.||.. .
VYAQRYDCVTIMFADIVGFTAFCSRCSMNNMPMQCVRMLNDHYTCFDRLCDQHKFGCYKVKTIGDCYMCVSGLPPPCVQWCCCWHHAWCMADMALDMMEY

VGSFRMRHMPEVP-----VRIRIGLHSGPCVAGVVG--LTMPRYCLFGDTVNTASRMESTGLPY--RIHVNMSTVRILRALDQGFQMEC----RGRTELK
.....  | .  |     ...|||.|.||.||||.|  . |||||..|||||.||||||||.|.  .|||  .|.|.|.... .||.||    ||  ..|
CQQVNVHHFNREPPTWNCIQMRIGIHTGPVVAGVIGSFQRMPRYCVWGDTVNVASRMESTGVPGSCKIHVSEETYRCLKCHE-NFQFECHLQHRGEIPVK

GKGIE---DTYWLVG
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GKGKMGEMETYFLHG
HNOBA CYGD.AA HNOBA 838-868 51 4.1e-11 41.76 Pfam 204-234 (234) Show / Hide 
Range on Protein: 838-868
Range on HMM: 204-234/234
Sequence Identity: 51% (16 aa)

IRERTEELEQEKQKTDRLLTQMLPPSVAEAL
... ..||| ||.|||.|| .|.|.|||. |
LEQMHRELEEEKKKTDDLLYSMFPKSVANRL