Gene KSGC (Mouse)

KSGC

Species: Mouse
Alias: 2410077I05Rik, KSGC
External Links: MGI , Entrez Gene , Refseq cDNA , Refseq Protein , Phosphosite , iHOP
Annotation:

Classification

Group: RGC
Family: RGC

Sequence

Name Sequence Type Origin Length Description Download
KSGC.kin_dom Protein Kinase Domain Sugen global kinase HMM prediction 268 Kinase domain by global Sugen HMM Fasta, JSON
KSGC.NA RNA Sugen 3891 None Fasta, JSON
KSGC.AA Protein Sugen 1101 None Fasta, JSON

Protein domain

Protein domains of KSGC.AA. The domains are annotated by HMM profiles from Pfam and SMART, as well as in-house data which includes HMMs of each individual kinase group, family and subfamily. Here is domain list in details, including sequence identity, significance and alignment. In particular, you can find can find the best hit kinase group/family/subfamily, which is helpful to understand the relationship between kinases.Kinase domain and best hit kinase group/family/subfamily are highlighted in red and blue. Visualized by pviz.

Usage: Zoom in selected region by dragging mouse and zoom out by double-clicking.

Show/hide domain list
Domain Protein name Domain Name Range Identity (%) Significance Score Profile Source Profile Range (length) Alignment
ANF_receptor KSGC.AA ANF_receptor 64-188 15 2.1e-08 30.55 Pfam 1-130 (364) Show / Hide 
Range on Protein: 64-188
Range on HMM: 1-130/364
Sequence Identity: 15% (20 aa)

RLGAGLQTVVDKLNSEPV-GLGNVSWEFTYTNST--CSAKESLAVFIDQVQKEHISALFGPACPEAAEVIGLLASEWNIPLFDFVGQMAALKD--HFWCD
.......  .. .|..|   | ...... ....   .     .|.  .... . . |..|| |..... .. .|..||||.. .     .| |      .
QCAPAMRMAIEDINADPGILLPGITLGYHDDDCCYCSDC-QAVAAADCCWH-KGVVAIIGPSCSYVCIPVARIANHWNIPMISWGCTCPCLTDKAKNRYP

TCVTLVPPKQEI-SAVLRESLRY-LGWEHIGV
. . .||.     .... . ... .|| ...|
YFFRTVPSDTYQYGWAMVDIIQHHFGWKWVAV
ANF_receptor KSGC.AA ANF_receptor 243-416 21 8.7e-20 70.8 Pfam 192-364 (364) Show / Hide 
Range on Protein: 243-416
Range on HMM: 192-364/364
Sequence Identity: 21% (42 aa)

ARVIILICSSEDA----RRILQAAVDLGLDTGEFVFILLQQLEVGFWKEVLTKDKVIRFPKVYESVFLI--APSAYGGGIGDDG--------FRKQVSQE
||||.. |...|.    |.|.|.|..||...|..|.|.   .  ...               |... .   .  |..| .|.          |.....  
ARVIVMCCYPDDMGLLQRQIMQQAHELGMMSGGYVWIYTDWWMHSYDMQ-W----------WYDDDMDNDKFREAMKGVLGFTMHPSPEFQEFMQRWKK-

LRRPPFQSSITSEDQVSPYSAYLHDALLLYAQTVEEMRKAEKDFRDGR---------QLISTLRAGQVTLQGITGPVLLDSQGKRHVDYSVYALQES
           . .....|.||..|| .|||. ...|......  .|          ||.. ...  |. .|.||.| .|. | |..||......  
-----------TDTEMNYYAAYAYDAVYLYAHALHNMLRCDPNHWNGGCDIMKWHGWQLLHYMWN-KVNFEGVTGDVQFDDNGGRRPDYMYWIMNWD
Kinase KSGC.AA RGC 579-829 36 3.6e-116 392.26 In-house 1-300 (300) Show / Hide 
Range on Protein: 579-829
Range on HMM: 1-300/300
Sequence Identity: 36% (108 aa)

QGNQVALCYIGDEA--EAWVKKPTVRREVCLMCELKHENIVPFFGVCTEPP------NICIVTQYCKKGSLQDVMRNSDHEIDWIFKLSFAYDIVNGLLF
.|..|... .   .   .|  .....||...|..|.|.|...|.| |..||      |.|||..|| .|||||...|.|.. || ||.|| .|||.|. .
EGDWVWIKKHNQRNLFRHWDFTRSMMRELKQMRQLQHDNLNKFIGMCIDPPMEYHPGNMCIVWEYCSRGSLQDILENDDIKMDWMFKYSFIRDIVKGMQY

LHGSPLRSHGNLKPSNCLVDSHMQLKLSGFGL-----WEFKHGST----------WRSYNQEATDHSELYWTAPELLR-LRESPCSG--------TPQGD
|| ||.|.|||||..||.|||....|...|||     ..||||..          | . ..| . .... |||||.||  |.....|        |..||
LHHSPIRYHGNLKSWNCVVDSRWVVKITDFGLNNPLCHWFKHGQINPPCKSDDKSWQRQHDEHPYYKKMLWTAPEHLREWRMPHQWGPHRQTQRGTQKGD

VYSFAILLRDLIHQQAHG---PFEDL----EAAPEEIISRIKDP---RAPVPLRPSLLED------KGDGRIVALVRECWDESPELRP-IFPSIKKTLRE
||||.| .  .|. . .    ||...    |  |.||| ..| |   . . |.|||. ||      .   ....|.|.||.| || || .| .|.|.|..
VYSFGIIMYEIITRKGPWDLEPFCMWPGEYELSPMEIIEEVKYPPKKGGQKPFRPSIHEDEEGHMIECNPCLLHLMRDCWAEDPEERPDMFDQIRKQLKT
Kinase KSGC.AA RGC 579-829 36 3.6e-116 392.26 In-house 1-300 (300) Show / Hide 
Range on Protein: 579-829
Range on HMM: 1-300/300
Sequence Identity: 36% (108 aa)

QGNQVALCYIGDEA--EAWVKKPTVRREVCLMCELKHENIVPFFGVCTEPP------NICIVTQYCKKGSLQDVMRNSDHEIDWIFKLSFAYDIVNGLLF
.|..|... .   .   .|  .....||...|..|.|.|...|.| |..||      |.|||..|| .|||||...|.|.. || ||.|| .|||.|. .
EGDWVWIKKHNQRNLFRHWDFTRSMMRELKQMRQLQHDNLNKFIGMCIDPPMEYHPGNMCIVWEYCSRGSLQDILENDDIKMDWMFKYSFIRDIVKGMQY

LHGSPLRSHGNLKPSNCLVDSHMQLKLSGFGL-----WEFKHGST----------WRSYNQEATDHSELYWTAPELLR-LRESPCSG--------TPQGD
|| ||.|.|||||..||.|||....|...|||     ..||||..          | . ..| . .... |||||.||  |.....|        |..||
LHHSPIRYHGNLKSWNCVVDSRWVVKITDFGLNNPLCHWFKHGQINPPCKSDDKSWQRQHDEHPYYKKMLWTAPEHLREWRMPHQWGPHRQTQRGTQKGD

VYSFAILLRDLIHQQAHG---PFEDL----EAAPEEIISRIKDP---RAPVPLRPSLLED------KGDGRIVALVRECWDESPELRP-IFPSIKKTLRE
||||.| .  .|. . .    ||...    |  |.||| ..| |   . . |.|||. ||      .   ....|.|.||.| || || .| .|.|.|..
VYSFGIIMYEIITRKGPWDLEPFCMWPGEYELSPMEIIEEVKYPPKKGGQKPFRPSIHEDEEGHMIECNPCLLHLMRDCWAEDPEERPDMFDQIRKQLKT
Kinase KSGC.AA TKL 602-827 24 2.4e-45 156.94 In-house 71-364 (364) Show / Hide 
Range on Protein: 602-827
Range on HMM: 71-364/364
Sequence Identity: 24% (73 aa)

RREVCLMCELK--HENIVPFFGVCTEPPN-------------ICIVTQYCKKGSLQDVMRNSDHEIDWIFKLSFAYDIVNGLLFLHG-------SPLRSH
..|. .|. ..  |.|||.| |.|..||.             .|||..||..||| ...        |  ....|.||  |. .||         |   |
FEEEEIMMMSRLRHPNIVQFMGYCCCPPCGCVCMHPVGPWGQLCIVMEYCPGGSLLHYLH-------WHQRCRWALDIARGMNYLHSMNPKWCTKPPIIH

GNLKPSNCLVDSHMQ--------------LKLSGFGLWEFKHGS----------------TWRSYNQEATDHSELYWTAPELLRLRESPC----------
 .||..|.|||....              .|.. |||  |...|                  .. ..  |    ..| |||.||  .  .          
RDLKSKNILVDENWTNVSNYMYNPNADWCCKICDFGLSRFMSQSGNMNDTMTTMMESAEHQ-NNRKTTMTQCGTPRWMAPEVLRGQMNYTEKVGIDEFCK

--SGTPQGDVYSFAILLRDLIHQQAHGPFEDLEAAPEE---------IISRIKDPRAPVPLRPS-----LLEDKGDGRIVALVRECWDESPELRPIFPSI
  . ... |||||.|.|  ..  .   |..|.   |..         ..   |  | |.| ...       ..  . ..  |  .|||. || || |  |
GFEYSEKCDVYSFGIVLWEILTRCR--PYYDYPYMPMIFQDPFEEMFMMVCDKGLRPPIPPIWQNHHKMCPCPDCPPSMKKLMQDCWDHDPEKRPSFQEI

KKTL
.|.|
LKRL
Kinase KSGC.AA TKL-Unique 602-754 33 3.2e-32 111.0 In-house 43-218 (290) Show / Hide 
Range on Protein: 602-754
Range on HMM: 43-218/290
Sequence Identity: 33% (59 aa)

RREVCLMCELK-HENIVPFFGVCT----EPPNICIVTQYCKKGSLQDVMR---------NSDHEIDWIFKLSFAYDIVNGLLFLHGSPL-RSHGNLKPSN
..|| .|  |. |.||| ..|.|.     ||| |||. ||  ||| ||           |. .....  ....| ||. |. .|| .     |..||.||
ENEVNWMKKLHYHPNIVHYMGYCMDHQVYPPNMCIVMEYCPGGSLYDVLHQNNNNNNNNNNNCKLNMQQRVKMAIDIAQGMYYLHHCEPPIIHRDLKSSN

CLVDSH-----MQLKLSGFGLWEFKHGSTWRSYNQE-----ATDHSELYWTAPELLRLRESPCSGTPQGDVYSFAILL
 |||..     .. |...|||  |.  ..  ..|       .|  ... | |||.||  .  |  . . |||||.| |
FLVDNNSNIAEWNIKICDFGLSKFNSKINKMTNNEHKGTRNQTRCGSFRWMAPEVLRMNF--CQYSEKSDVYSFGIVL
Kinase KSGC.AA DRK 602-702 41 6e-26 84.89 In-house 45-146 (258) Show / Hide 
Range on Protein: 602-702
Range on HMM: 45-146/258
Sequence Identity: 41% (42 aa)

RREVCLMCELKHENIVPFFGVCTEPPNICIVTQYCKKGSLQDVMRNSDHEIDWIFKLSFAYDIVNGLLFLHGS-PLRSHGNLKPSNCLVDSHMQLKLSGF
.||. ||| | | ||. | | |..|| |||.. |  .|||  .  .   |.||   .. . |.  |. .||.. |   |  ||  | ||| | | | . |
HREINLMCQLRHPNICQFMGTCNNPPDICICMEYMPRGSLYNILHDESIEMDWPLMKQMMFDCAKGMIYLHCCNPIIIHRDLKSHNLLVDEHWQVKVADF

GL
||
GL
Kinase KSGC.AA RIPK 603-827 25 1.4e-25 84.07 In-house 45-290 (290) Show / Hide 
Range on Protein: 603-827
Range on HMM: 45-290/290
Sequence Identity: 25% (63 aa)

REVCLMCELKHENIVPFFGVCTEP-----PN-ICIVTQYCKKGSLQDVMRNSD----HEIDWIFKLSFAYDIVNGLLFLHGSP---LRSHGNLKPSNCLV
.|.  |  |..|.|||  |.| ..     .. . ||..| ..||| ..         | . |  .    . |. |  .||.     .  |  |||.| ||
EEAKHMHKLRCEHIVPIYGFCQCEEWDCDCKLYGIVMEYMENGSLWHFLHTKWPYQHHPDPWPLRCRMIHEISCGMCYLHSMNPPII--HRDLKPENILV

DSHMQLKLSGFGLWEFKHGSTWRSYNQ-----EATDHSE----LYWTAPELLR--LRESPCSGTPQGDVYSFAILLRDLIHQQAHGPFEDLEAAPEEIIS
|...  |.. |||  .. .|.  .  .       ..  .    |.  .||..|  .. .    ||  |||||||..  .  |    |.|| .  .. |. 
DNNFHVKIADFGLATWMMWSHSHQDRCNQREVYSMKSKNRWGTLSYMPPEHFRTDNKKPIKVVTPKYDVYSFAIVMWEVLTQKH--PYED-RKCMMMIMM

RIKDPRAPV--PLRPSLLEDKGDGRIVALVRECWDESPELRPIFPSIKKTL
..|   .|   |. ..  |. .  ... | ..||.  |. || |. ..   
CCKQGHRPCLQPVPEYWPEPPHCEQMIELMQRCWQQDPNDRPCFQECEEWT
Kinase KSGC.AA Dicty4 602-702 34 4.5e-23 73.93 In-house 46-160 (277) Show / Hide 
Range on Protein: 602-702
Range on HMM: 46-160/277
Sequence Identity: 34% (40 aa)

RREVCLMCELKHENIVPFFGVCT----EPPNICIVTQYCKKGSLQDVMRN------SDHEIDWIFKLS---FAYDIVNGLLFLHG-SPLRSHGNLKPSNC
|.|| .|| . | ||. | | ||    .|. .|||| |. ||.|  . ..      .  ..||.  ..    | |.. |.  ||.  |   |  ||..| 
RKEVHIMCKIRHPNICLFMGACTAPRSHPGKMCIVTEYMPKGNLYSLLHDKPSEQQQSIKLDWPLIKRAMRMAFDAARGMNWLHCCNPVIIHRDLKSHNL

LVDSHMQLKLSGFGL
||| ... | . |||
LVDKNWRVKVCDFGL
Kinase KSGC.AA TK 603-754 15 4.9e-23 73.39 In-house 90-384 (486) Show / Hide 
Range on Protein: 603-754
Range on HMM: 90-384/486
Sequence Identity: 15% (45 aa)

REVCLMCE--LKHENIVPFFGVCTEP------------PNICIVTQYCKKGS----LQDVMRNSDHE---------------------------------
.| ..||.  ..|.||| ..||||..            . ..||. |...|.    |.|  |.....                                 
EEMKMMCHSLGHHPNIVRLYGVCTQGEPKPCFEVVVHQEPWMIVMEYMPHGDMDGSLRDYLRKCRPKFQHEQDCPDNQHNKYPPSKLHHCMKGDITYSHE

------------------------------------------IDWIFKLSFAYDIVNGLLFLHGSPLR-----SHGNLKPSNCLVDSHMQ----------
                                          ..   .| ....| .|. .||  . .      |..|   ||||.....          
SNSPCPEEQDYDDDLIKDHPPPLTTKDLLQMAWQWCLTCKHQLTMHQLL-MCWQIACGMEYLHSKNCEFIQNFVHRDLAARNCLVGENNVCKWHFDGCGP

-LKLSGFG----------LWEFKHGSTWRSYNQEA--------------------TDHSELYWTAPELLRLRES-----PCSGTPQGDVYSFAILL
  |.. ||              ...  .|. .. .                     .   . |.||| |. |.          |.. ||.|| .|.
VCKIADFGLSRQGSGVLARDIYSDDDYYRKSSYGTGRPMWPFEDDPWQDYYRQQSGGKLPIRWMAPECLNDRVFSEAEKYGKFTTKSDVWSFGVLM
Kinase KSGC.AA MLK 596-754 24 1.5e-21 71.57 In-house 32-226 (291) Show / Hide 
Range on Protein: 596-754
Range on HMM: 32-226/291
Sequence Identity: 24% (51 aa)

VKKPT---------------VRREVCLMCELKHEN----IVPFFGVCTEPPN-ICIVTQYCKKGSLQDVMRN-------------SDHEIDWIFKLSFAY
||. .               ...|. .   |.|.|    |..| |||..||.  |||..|| .||| .| ..             .|  .|  .....|.
VKRVRARIFDKSDTYCEQWDFEMECRHLRILSHPNNHPCIIQFYGVCLQPPCHFCIVMEYCEGGSLYNVLHGARSKWMDANHNQKNDRVYDHDHAMNWAL

DIVNGLLFLHG-SP-LRSHGNLKPSNCLVDS------HMQLKLSGFGLWEFKHGS----TWRSYNQEATDHSELYWTAPELL-RLRESPCSGTPQGDVYS
.. .|. .||   | .  |  ||..| |.|       |..|| . ||.  ..| .    . . ..        . | ||| . ..|....|     ||.|
QCARGMHYLHSMAPKPIIHRDLKSHNILIDEICHDMHHGTLKICDFGTSRDWHQMCTNMMSNAGT--------YAWMAPEVIQQFRCEKYSEK--CDVWS

FAILL
....|
WGVVL
Kinase KSGC.AA Pkinase_Tyr 603-672 32 9.7e-17 57.32 Pfam 52-128 (270) Show / Hide 
Range on Protein: 603-672
Range on HMM: 52-128/270
Sequence Identity: 32% (25 aa)

REVCLMCEL-KHENIVPFFGVCT--EPP-NICIVTQYCKKGSLQDVMRNS---DHEIDWIFKLSFAYDIVNGLLFLH
||. .|..| .|.||| . ||||  . | .|.||. |...|.| |  |.    .. ..   .|.....| .|. .|.
REAKIMKQLGHHPNIVRLYGVCTDQGEPNQIYIVMEYMPHGDLLDYLRKHREDKQPLTMKDLLQMCWQIAKGMEYLE
Kinase KSGC.AA LRRK 602-694 32 2.4e-15 50.72 In-house 105-204 (351) Show / Hide 
Range on Protein: 602-694
Range on HMM: 105-204/351
Sequence Identity: 32% (34 aa)

RREVCLMCELKHENIVPFFGVCTEPPNICIVTQYCKKGSLQDVMRNSD-HE-------IDWIFKLSFAYDIVNGLLFLHGSP----LRSHGNLKPSNCLV
|.|| .|..|.| |||. .|.| .|  .|.|. |   |.|.....|.  ..       |.| .||  |..|  |. .|| .      |   .||. | |.
RHEVWIMSHLNHPNIVSLKGFCIHP--LCMVMEYAPHGDLYHFLHNKKQDGFHFMKAHISWMLKLKIALQIAKGMEYLHSHNPPIIHR---DLKSPNILL

DSHMQ
 |..|
WSSPQ
TyrKc KSGC.AA TyrKc 561-827 23 1.6e-14 12.11 SMART 1-280 (280) Show / Hide 
Range on Protein: 561-827
Range on HMM: 1-280/280
Sequence Identity: 23% (70 aa)

LVKRHQDEELFFAPVGLYQGNQVALCYIGDEAEAWVKKPT------VRREVCLMCEL--KHENIVPFFGVCTEP-------PNICIVTQYCKKGSLQDVM
... ..  | .|  | . . .           .  ||.         .||  .||.|  .|.||| ..||||..       . ..||. |...|.|.|  
ITLGKKLGEGAFGEVYKGTWK----------IQVAVKMLKEDAREDFMREARIMCKLGGHHPNIVRLYGVCTQQGRNFMYIEPLMIVMEYMPHGDLKDYL

RNSDHEIDWIFKLSFAYDIVNGLLFLHGSPLRSHGNLKPSNCLVDSHMQLKLSGFGLWEFKHGS-TW----RSYNQEATDHSE----LYWTAPELLRLRE
|.. ... .  .|||...| .|  .||  ..  |  |   ||||..  . | | |||  . .   ..      | .  ....     . |.||| .. ..
RKHRPKLCMKDLLSFCWQIACGMEYLHSKNC-IHRDLAARNCLVGENHTVKISDFGLSRDIYDDDQQGESKDYYRKKEHKGGKTMLPIRWMAPECINYGK

SPCSGTPQGDVYSFAILL---RDLIHQQAHGPFEDLEAAPEEIISRIKDP-RAPVPLRPSLLEDK----GDGRIVALVRECWDESPELRPIFPSIKKTL
     |.. ||.|| ...     .  |   |. .     ..|.| ..|.  | | |  .   .          .  . ..||.| || || |  |.. .
F----TTKSDVWSFGVCMWEIFTYGQQPYPGMIQQ-MMSNQEVIEYVKQGYRMPQPPNDY--P-MSFVCCPDEMYQIMKQCWHEDPEDRPTFSEIHECF
Kinase KSGC.AA Pkinase 600-702 28 2.5e-14 51.77 Pfam 44-158 (293) Show / Hide 
Range on Protein: 600-702
Range on HMM: 44-158/293
Sequence Identity: 28% (33 aa)

TVRR--EVCLMCELKHENIVPFFGVCTEPPNICIVTQYCKKG----SLQDVMR-NSDHEI--DWIFKLSFAYDIVNGLLFLHGSPLRSHGNLKPSNCLVD
| ||  |...| .|.|.||| ..........|..|. || .|    .| |...  ..  .  ..    ...| |. || ..|      |  |||.|.|.|
THRRLSEIQIMKRLNHPNIVRLYDWFEDKDHIYMVMEYCEGGLYVMDLFDYISTWRHGCFYFSEWECKFYMYQILRGLEYCHSMGI-IHRDLKPENILID

SHMQL----KLSGFGL
.....    |.. |||
NNGHIDACVKICDFGL
S_TKc KSGC.AA S_TKc 569-825 18 1.8e-12 5.96 SMART 1-220 (231) Show / Hide 
Range on Protein: 569-825
Range on HMM: 1-220/231
Sequence Identity: 18% (50 aa)

ELFFAPVGLYQGNQVALCYIGD-EAEAWVKK--PTVRREVCLMCELKHENIVPFFGVCTEPPNICIVTQYCKK--GSLQDVMRNSDHE-----IDWIFKL
  .  ..|     .| .|.  .   .  .|.   ..|||. .. . .|.||| ...|. .  ....|. ||    |.| |....  ..     ..     
YEILRKIGKGAFGKVYKCRHKKTGRIVAIKIIKEHIRREIQILKK-HHPNIVKLYDVFQD-DHLYMVMEYCDGDLGDLFDYIKKRGRHGLRFPFPE-HAR

SFAYDIVNGLLFLHGSPLRSHGNLKPSNCLVDSHMQLKLSGFGLWEFKHGSTWRSYNQEATDHSELYWTAPELLRLRESPCSGTP-QGDVYSFAILLRDL
...| |...| ..|      |  |||.| |.|.  ..|.. |||  .             |    ... |||.|       . ..   |..|. ..|  .
FYMYQICCALEYCHSH-GIIHRDLKPENILLDE--HIKICDFGLARQL-----------TTFCGTPWYMAPEVL-------GYGKCKCDWWSCGCILYEM

IHQQAHGPFEDLEAAPEEIISRIKDPRAPVPLRPSLLEDKGDGRIVALVRECWDESPELRPIFPSIKK
.  .   ||.     ..... .|.                 .     ..| |..  || ||    . .
LCGYP--PFP----QMQMMFKKIG-----------------SPEAKDFIRKCLQKDPEKRPTA-EALQ
Kinase KSGC.AA LRRK 746-829 27 3.2e-09 28.76 In-house 264-351 (351) Show / Hide 
Range on Protein: 746-829
Range on HMM: 264-351/351
Sequence Identity: 27% (26 aa)

DVYSFAILLRDLIHQQAHGPFEDLEAA-----PEEIISRIKDPRAPVPLRPSLLED-KGDG----RIVALVRECWDESPELRPIFPSIKKTLRE
|.|||...| .|.. | | ||....        |.|  .|..      |||.. ..  .      .  .|  .||.. |. || | .| |.| .
DCYSFGMILWELLTRQ-HHPFDEHDFFDHMQWMEQIEDKIIE-----GLRPTIPQHYCPPCQPWHMYQDLIQHCWQHDPKKRPHFSQIVKRLSQ
Kinase KSGC.AA Dicty4 796-829 30 3.9e-05 13.27 In-house 242-277 (277) Show / Hide 
Range on Protein: 796-829
Range on HMM: 242-277/277
Sequence Identity: 30% (11 aa)

DKGDGRIVALVRECWDESPELRPIFPSIKKT--LRE
| .. .. .|. .|||..|. || |. | .   | .
DWCPPSWKHLIQWCWDHDPQHRPSFEEIIQRRILEH
Kinase KSGC.AA DRK 803-830 35 0.00014 11.47 In-house 232-258 (258) Show / Hide 
Range on Protein: 803-830
Range on HMM: 232-258/258
Sequence Identity: 35% (10 aa)

VALVRECWDESPELRPIFPSIKKTLREA
..|  .||.| |  || .. . . | ||
IQLMNDCWNEDPQHRPSMQECLERL-EA
Kinase KSGC.AA MLK 801-827 33 0.000259 11.02 In-house 265-291 (291) Show / Hide 
Range on Protein: 801-827
Range on HMM: 265-291/291
Sequence Identity: 33% (9 aa)

RIVALVRECWDESPELRPIFPSIKKTL
..  |  .||.. |. || | .| . |
HWKKLMKQCWNQDPHKRPSFRQIVQHL
Kinase KSGC.AA TK 805-827 39 0.000386 8.93 In-house 464-486 (486) Show / Hide 
Range on Protein: 805-827
Range on HMM: 464-486/486
Sequence Identity: 39% (9 aa)

LVRECWDESPELRPIFPSIKKTL
| ..||.. || || |  ... |
LMQQCWHYDPEDRPTFSQLHEQL
Kinase KSGC.AA TKL-Unique 805-827 39 0.003359 7.35 In-house 268-290 (290) Show / Hide 
Range on Protein: 805-827
Range on HMM: 268-290/290
Sequence Identity: 39% (9 aa)

LVRECWDESPELRPIFPSIKKTL
| ..||.  |. || | .| . |
LIQQCWHHDPSQRPSFDEIIHRL
Kinase KSGC.AA DRK 726-754 55 0.009887 5.12 In-house 168-192 (258) Show / Hide 
Range on Protein: 726-754
Range on HMM: 168-192/258
Sequence Identity: 55% (16 aa)

WTAPELLRLRESPCSGTPQGDVYSFAILL
|||||   ||. .   |   ||||||| |
WTAPEV--LRNQRY--TEKADVYSFAIVL
Kinase KSGC.AA Pkinase_Tyr 807-827 42 0.029026 8.29 Pfam 250-270 (270) Show / Hide 
Range on Protein: 807-827
Range on HMM: 250-270/270
Sequence Identity: 42% (9 aa)

RECWDESPELRPIFPSIKKTL
..||.. || || |  |   |
KQCWHYDPEDRPTFSEIHEQL
Kinase KSGC.AA Dicty4 746-754 77 0.117246 1.5 In-house 199-207 (277) Show / Hide 
Range on Protein: 746-754
Range on HMM: 199-207/277
Sequence Identity: 77% (7 aa)

DVYSFAILL
|||||.|.|
DVYSFGIVL
Kinase KSGC.AA Pkinase_Tyr 686-702 47 5.26608 0.64 Pfam 141-157 (270) Show / Hide 
Range on Protein: 686-702
Range on HMM: 141-157/270
Sequence Identity: 47% (8 aa)

NCLVDSHMQLKLSGFGL
||||.. .. | . |||
NCLVTENNVVKICDFGL
CYCc KSGC.AA CYCc 866-1060 46 3.5e-98 333.4 SMART 1-231 (231) Show / Hide 
Range on Protein: 866-1060
Range on HMM: 1-231/231
Sequence Identity: 46% (107 aa)

AEKRKVEKLLSTMLPSFVGEQLIAGK-SVEPEHFESVTIFFSDIVGFTKLCSLSSPLQVVKLLNDLYSLFDHTIQSHD-----VYKVETIGDAYMVASGL
.||.| ..||  |||  | .|| .|. .|.|.....||| |.||||||.||| ..|.|||..|||.|. ||  |  |.     .||||||||||||.||.
MEKQKNDRLLCQMLPRHVANQLKQGRHPVWPPCYDCVTILFTDIVGFTNLCSWCTPMQVVNMLNDHYTRFDRIIDRHGCYHNYCYKVETIGDAYMVVSGC

PIRNG-------------------AQHADEIATMALHLLSVTTHFQIGHM----PEERLKLRIGLHTGPVVAGVVGITMPRYCLFGDTVNMASRMESSSL
| ||.                   .||| .|| .||. ... ..|.. |     |.. |..|||.||||||.|||||.|||||.|||||||||||||...
PTRNEHNQCQCLHHWWTWCFWCFHWQHAQWIADWALDMVECMKTFHVQHHMGELPWNPLRMRIGIHTGPVVCGVVGIRMPRYCYFGDTVNMASRMESTGD

PLRIHVSQSTAGAL-------LAAGGYHLQK
| .||||..|  .|        . |..... 
PGQIHVSEETYWCLCLDQFERRRCGQFEFEP
Guanylate_cyc KSGC.AA Guanylate_cyc 893-1079 44 1e-90 312.51 Pfam 1-214 (214) Show / Hide 
Range on Protein: 893-1079
Range on HMM: 1-214/214
Sequence Identity: 44% (95 aa)

VEPEHFESVTIFFSDIVGFTKLCSLSS----PLQVVKLLNDLYSLFDHTIQSH--DVYKVETIGDAYMVASGLPIR-----NGAQHADEIATMALHLLSV
|... ...|||.|.||||||..|| .|    |.|.|..|||.|. ||. .  |  ..|||.||||.||..|||| .     ....||  .| ||| ..  
VYAQRYDCVTIMFADIVGFTAFCSRCSMNNMPMQCVRMLNDHYTCFDRLCDQHKFGCYKVKTIGDCYMCVSGLPPPCVQWCCCWHHAWCMADMALDMMEY

TTHFQIGHMPEER-----LKLRIGLHTGPVVAGVVG--ITMPRYCLFGDTVNMASRMESSSLPL--RIHVSQSTAGALLAAG----GYHLQKRGTISVKG
 . ....| . |.     ...|||.|||||||||.|  . |||||..|||||.|||||| ..|.  .||||..|.  | . .    ..||| || |.|||
CQQVNVHHFNREPPTWNCIQMRIGIHTGPVVAGVIGSFQRMPRYCVWGDTVNVASRMESTGVPGSCKIHVSEETYRCLKCHENFQFECHLQHRGEIPVKG

KGEQ---TTFWLKG
||..   .|..|.|
KGKMGEMETYFLHG