Gene LMR2 (Mouse)

LMR2

Species: Mouse
Alias: LMR2
External Links: Entrez Gene , Refseq cDNA , Refseq Protein , Phosphosite , iHOP
Annotation:

Classification

Group: TK
Family: Lmr

Sequence

Name Sequence Type Origin Length Description Download
LMR2.kin_dom Protein Kinase Domain Sugen global kinase HMM prediction 274 Kinase domain by global Sugen HMM Fasta, JSON
LMR2.NA RNA Sugen 8114 None Fasta, JSON
LMR2.AA Protein Sugen 1471 None Fasta, JSON

Protein domain

Protein domains of LMR2.AA. The domains are annotated by HMM profiles from Pfam and SMART, as well as in-house data which includes HMMs of each individual kinase group, family and subfamily. Here is domain list in details, including sequence identity, significance and alignment. In particular, you can find can find the best hit kinase group/family/subfamily, which is helpful to understand the relationship between kinases.Kinase domain and best hit kinase group/family/subfamily are highlighted in red and blue. Visualized by pviz.

Usage: Zoom in selected region by dragging mouse and zoom out by double-clicking.

Show/hide domain list
Domain Protein name Domain Name Range Identity (%) Significance Score Profile Source Profile Range (length) Alignment
Kinase LMR2.AA Lmr 136-409 66 6.2e-228 763.51 In-house 1-283 (283) Show / Hide 
Range on Protein: 136-409
Range on HMM: 1-283/283
Sequence Identity: 66% (189 aa)

LNYIQEIGSGWFGKVLLGETYT---GTSVARVIVKELKVSASPKEQDTFLKSGEPYYILQHPNVLQCVGQCVEAIPYLLVFEFCDLGDLKAYLHNEQ--E
||||||||.||||||||||...   |.|.|.|.||||..||||.||..||....||..|||||||||.|||||.||||||.|||..||||.||....  |
LNYIQEIGNGWFGKVLLGEVHSLHPGMSKAQVVVKELRASASPQEQMQFLQEVQPYRELQHPNVLQCLGQCVETIPYLLVMEFCPYGDLKNYLRKCRPME

HVRGDS---QTMLLQRMACEIAAGLAAMHKLHFLHSDLALRNCYLTSDLNVKVGDYGIGFSRYKEDYIETDDK-KVFPLRWTAPELVTSFQDRLLTADQT
|...|.   |||.|||||||||.|||.||..||.|||||||||.|..||.||.||||.....|||||..|.|. ...||||.||||...|...||..|||
HMMPDKPPRQTMTLQRMACEIACGLAHMHQHHFVHSDLALRNCQLCADLTVKIGDYGLAHCQYKEDYYITKDQCHWVPLRWIAPELMDEFHQNLLVVDQT

KYSNIWSLGVTLWELFNNAAQPYANLSDLDVLNQVIRERDMKLPKPQLEQPYSDRWYEVLQFCWLPPDKRPAAEDVHRLLTYL
|||||||||||.||||..|||||...||..||.||.||.|.|||||||..||||||||..||||..||.||.|||||||||||
KYSNIWSLGVTMWELFEFAAQPYPHHSDEQVLAQVVREQDIKLPKPQLQLPYSDRWYEIMQFCWMQPDQRPTAEDVHRLLTYL
Kinase LMR2.AA TK 136-406 16 8.3e-72 239.78 In-house 1-486 (486) Show / Hide 
Range on Protein: 136-406
Range on HMM: 1-486/486
Sequence Identity: 16% (79 aa)

LNYIQEIGSGWFG---KVLLGETYTGT-----------------------SVARVIVKELKV--SASPKEQDT--------------FLKSGEPYY--IL
. .....|.|.||   .| .|| ...                         . .| || ||   ..|..|.                ..   .     ..
ITLGKKLGEGQFGSFGEVYKGEWRGRNPWNGKRFPCHMTVTLKCKNGKEGGKTPVAVKMLKEGDAMSQEEFFDEEMHDRDGGEDFLEEAEEMKMMCHSLG

QHPNVLQCVGQCVEA------------IPYLLVFEFCDLGD----LKAYLHNEQEHVRG-----------------------------------------
.|||.....| |..              |...| |....||    |. ||..  .. .                                          
HHPNIVRLYGVCTQGEPKPCFEVVVHQEPWMIVMEYMPHGDMDGSLRDYLRKCRPKFQHEQDCPDNQHNKYPPSKLHHCMKGDITYSHESNSPCPEEQDY

----------DSQTMLLQR-------------------MACEIAAGLAAMHKL------HFLHSDLALRNCYLTSDLN-----------VKVGDYGIG--
          . .|  | .                   |.. ||.|.. .|..      .| | ||| ||| ......           .|..|.|    
DDDLIKDHPPPLTTKDLLQMAWQWCLTCKHQLTMHQLLMCWQIACGMEYLHSKNCEFIQNFVHRDLAARNCLVGENNVCKWHFDGCGPVCKIADFGLSRQ

----FSR---YKEDYIETDD-----------------------KKVFPLRWTAPELVTSFQDRLL--TADQTKYSNIWSLGVTLWELFNNA-AQPYANLS
     .|   ...||  ...                       .  .|.||.||| ... . .    .   |  | .||.||..||.| .. ...| ..|
GSGVLARDIYSDDDYYRKSSYGTGRPMWPFEDDPWQDYYRQQSGGKLPIRWMAPECLNDRVFSEAEKYGKFTTKSDVWSFGVLMWEIFTYGQEPYYGGMS

D---------LDVLNQVIR----------ERDMKLPKPQLEQPYS-------------DRWYEVLQFCWLP-PDKRPAAEDVHRLL
.          .|.... |          |   ....|| ..  .             . .|...| || . |..||  ...|. |
NQDVWKDGDNQEVMEYLRRGGRLCRSGLNEVGYRMRMPQPPHCPDWMRYRMHPPHCPPEEYYDLMQQCWHYDPEDRPTFSQLHEQL
Kinase LMR2.AA UTK 136-406 25 1.8e-47 160.43 In-house 1-296 (296) Show / Hide 
Range on Protein: 136-406
Range on HMM: 1-296/296
Sequence Identity: 25% (79 aa)

LNYIQEIGSGWFGKVLLGETYTGT---SVARVIVKELKVSAS-PKEQD---TFLKSGE---PYYILQ-HPNVLQCVGQCVEAIPYLLVFEFCDLGDLKAY
.   ...|.| || | ...  . .    ...| ||.....|. ..|..   .|..       .  .. |||||. || |.   | ..| |..  ||| .|
VQLGRQLGQGAFGEVHKARFTQCSEHMYEMDVAVKVCQHHADAQQEPEPYPDFMEEARELQMMKQFHWHPNVLRLVGVCTQEEPWMIVTEYMENGDLRSY

LHNEQEHV--RGDSQTML-LQRMACEIAAGLAAMHKLHFLHSDLALRNCYLTSD-------LNVKVGDYG-------IGF----SRYKEDYIETDD-KKV
| .  . .  .....|.  .  ||  ||.|.. .|  .| | ||| |||.....       . .|..|.|       ...    .||.|.| .. .  . 
LRRHRPTPPACPHWLTLHQRLCMAWDIARGMQYLHSCGFVHRDLAARNCLVHMHRMMWHCMMVCKIADFGRGGMSRRVNTFHFSNRYWESYYYMAQHQDR

FPLRWTAPELVTSFQDRLLTADQTKYSNIWSLGVTLWELFNNAAQPYANLSDLDVLNQVIRE-RDMKLPKPQLEQ--PYSDRWYEVLQFCWLP-PDKRPA
 |.||.||| .|.        . |  | .||.||..||.. ....||...|. .|. || .  |       ....    ... |.... || . |..|| 
WPIRWMAPEALTHHT------RFTTKSDVWSFGVVCWEIWTWGRLPYPGMSNMQVWHQVCNGGR------YRMPCPWDCPHPVYRLMHRCWHYDPQERPD

AEDVHRLL
.||.   .
FEDLVQQM
Kinase LMR2.AA Pkinase_Tyr 136-406 26 3.7e-45 153.55 Pfam 1-270 (270) Show / Hide 
Range on Protein: 136-406
Range on HMM: 1-270/270
Sequence Identity: 26% (76 aa)

LNYIQEIGSGWFGKVLLGETY--TGTSVARVIVKELKVSASPKE--QDTFLKSGEPYYIL-QHPNVLQCVGQCV-EAIP--YLLVFEFCDLGDLKAYLHN
.  ....|.| ||.| .|. .   .     | || || .|....  .. |..  .    | .|||.....| |. .  |  ...|.|.. .|||. ||..
ITFGKKLGEGAFGEVYKGTWKGDPDNTKIPVAVKMLKEGAMHEQNCREDFMREAKIMKQLGHHPNIVRLYGVCTDQGEPNQIYIVMEYMPHGDLLDYLRK

EQEHVRGDSQTMLLQRMACEIAAGLAAMHKLHFLHSDLALRNCYLTSDLNVKVGDYGIGFSRYK--EDYI-ETDDKKVFPLRWTAPELVTSFQDRLLTAD
   . ..   .  |  |. .||.|..  .  .. | ||| ||| .|... ||..| |   .|.   .||   . ..  .| .|.|||             
HR-EDKQPLTMKDLLQMCWQIAKGMEYLESKNCIHRDLAARNCLVTENNVVKICDFGL--ARDIYNDDYYYRKRGGGKLPIKWMAPECINYGK-------

QTKYSNIWSLGVTLWELFNNAAQP-YANLSDLDVLNQV-IRERDMKLPKPQLEQPY--SDRWYEVLQFCW-LPPDKRPAAEDVHRLL
 |  | .|| ||..||.|   .|| |...|. .|....  .         ....|   .|  |.... ||   |..||  ...|. |
FTTKSDVWSFGVLMWEIFTYGEQPTYPGMSNEEVYEYIYED-------GYRMPCPENCPDEIYDLMKQCWHYDPEDRPTFSEIHEQL
Kinase LMR2.AA TyrKc 136-406 26 2.1e-39 138.12 SMART 1-280 (280) Show / Hide 
Range on Protein: 136-406
Range on HMM: 1-280/280
Sequence Identity: 26% (80 aa)

LNYIQEIGSGWFGKVLLGETYTGTSVARVIVKELKVSASPKEQDTFLKSGEPYYIL--QHPNVLQCVGQCVEA-------IPYLLVFEFCDLGDLKAYLH
.  ....|.| ||.| .|. .       | || || .|    .  |..  .    |  .|||.....| |..         |...|.|....|||| ||.
ITLGKKLGEGAFGEVYKGTWK-----IQVAVKMLKEDA----REDFMREARIMCKLGGHHPNIVRLYGVCTQQGRNFMYIEPLMIVMEYMPHGDLKDYLR

NEQEHVRGDSQTMLLQRMACEIAAGLAAMHKLHFLHSDLALRNCYLTSDLNVKVGDYGIGFSRYKE---------DYIET----DDKKVFPLRWTAPELV
. ...     ..  |  ..  ||.| .  |. .. | ||| ||| ..... ||..| |   ||. .         ||. .    . | ..|.||.|||  
KHRPK----LCMKDLLSFCWQIACGMEYLHSKNCIHRDLAARNCLVGENHTVKISDFGL--SRDIYDDDQQGESKDYYRKKEHKGGKTMLPIRWMAPECI

TSFQDRLLTADQTKYSN---IWSLGVTLWELFNNAAQPYAN-----LSDLDVLNQVIRERDMKLPKPQLEQP-----YSDRWYEVLQFCWLP-PDKRPAA
          .  |..    .|| ||..||.| . .||| .     .|. .|...| . . |. |.  .  |      .|  |.. . ||   |..||  
----------NYGKFTTKSDVWSFGVCMWEIFTYGQQPYPGMIQQMMSNQEVIEYVKQGYRMPQPPNDY--PMSFVCCPDEMYQIMKQCWHEDPEDRPTF

EDVHRLL
...|...
SEIHECF
Kinase LMR2.AA TK-Unique 136-405 26 2.2e-39 133.52 In-house 1-294 (294) Show / Hide 
Range on Protein: 136-405
Range on HMM: 1-294/294
Sequence Identity: 26% (82 aa)

LNYIQEIGSGWFGKVLLGETYTGT---SVA-RVIVKELKVSASPKEQDTFLKSGEPYYILQ-HPNVLQCVGQCVEA-IPYLLVFEFCDLGDLKAYLHNEQ
|.  ..||.| || |  ||  ...   .   .|.|| || .|.. ... |||  . .  |  |||..||.|.|..  .| ....|.|  |.|  ||.. .
LEVGDVIGEGAFGQVWRGEVWGIWKHWDKQKCVAVKMLKDNATDTDKQDFLKEIQMMKELGDHPNIVQCLGCCTKSDEPWMIIMEYCPCGNLQHYLRTCR

-EHVRG---------------DSQTMLLQ-----RMACEIAAGLAAMHK--LHFLHSDLALRNCYLTSDLNVKVGDYGIGFSRY---KEDYIETDDKKVF
 .....               . .|  ..     . |..|| |.. ...   .. | ||. ||. ||.|...|..|.|.  .|.    ..|. .. ..  
PAMRQHQTYGNLKFDFHHMPDKPRTEPISPKDLYHFAWQIACGMEYLASQRKKIVHRDLCARNVLLTEDKVCKICDFGM--ARDVYTNGVYSMMCSQGRI

PLRWTAPELVTSFQDRLLTADQ-TKYSNIWSLGVTLWELFNNAAQPYANLSDLDVLNQVIRERDMKLPKPQLEQPY-SDRWYEVLQFCW-LPPDKRPAAE
|.|| |||          .    |  |..||.||..||.| . |.|| .... |..... .  .|..|     . . |.. |.... || . |..||  .
PIRWMAPESLKCY-----HGMYHTTKSDVWSFGVLMWEIFTLGACPYPGMPWKDIMECIRDGYRMPQP-----EHCCSHEMYNLMKSCWQWEPEERPSFR

DV-HRL
.. |||
QIKHRL
Kinase LMR2.AA Trk 136-406 30 2.1e-38 127.77 In-house 1-275 (275) Show / Hide 
Range on Protein: 136-406
Range on HMM: 1-275/275
Sequence Identity: 30% (88 aa)

LNYIQEIGSGWFGKVLLGETYTGTSVAR---VIVKELKVSASPKEQDTFLKSGEPYYILQHPNVLQCVGQCVEAIPYLLVFEFCDLGDLKAYL--HNEQE
.  ..|.| | |||| |.| |          | || ||  .  .   .| .  |    |||... .  | |..  | |.|||.   |||. ||  |    
IVLKWELGEGAFGKVFLAECYNLCPEQDKMMVAVKTLKDASE-NARKDFQREAELLTNLQHQHIVKFYGVCTDHDPLLMVFEYMKHGDLNKYLRQHGPDA

HVRGDSQT---------MLLQRMACEIAAGLAAMHKLHFLHSDLALRNCYLTSDLNVKVGDYGIGFSRYK-EDYIETDDKKVFPLRWTAPELVTSFQDRL
..  . |            .   | .||.|.  |  .|| | |.| |||    .| ||.||.|     |   ||   . .   | ||  ||   | . | 
MCYAQYQPRQAPGPLTIDQMLWIAKQIASGMVYMASQHFVHRDMATRNCLVGQNLIVKIGDFGMSRDVYSHTDYYRVGHHTMLPIRWMPPE---SIMYRK

LTADQTKYSNIWSLGVTLWELFNNAAQPYANLSDLDVLNQVIRERD-MKLPK--PQLEQPYSDRWYEVLQFCW-LPPDKRPAAEDVHRLL
 | .    | .||.||..|| |    ||.  || . | . .   |  .. |.  ||         |...  ||   | .|  . |.| ..
FTYE----SDVWSFGVVMWECFTYGKQPWYQLSNHEVIECIHQGRHRLERPRRCPQ-------EVYDIMLGCWQREPQQRMNIKDIHDII
Kinase LMR2.AA InsR 136-408 30 2.6e-30 98.94 In-house 1-278 (278) Show / Hide 
Range on Protein: 136-408
Range on HMM: 1-278/278
Sequence Identity: 30% (88 aa)

LNYIQEIGSGWFGKVLLG---ETYTGTSVA--RVIVKELKVSASPKEQDTFLKSGEPYYILQHPNVLQCVGQCVEAIPYLLVFEFCDLGDLKAYL----H
.  |.| | | ||.| .|       .   .  |. .| .. .|| .|   ||.  .      . .|    | |    | . | |. ..|||| ||    .
IVLIRECGQGSFGMVYEGIAKGIVPDEEWRFGRCAIKTVNENASMRERIEFLNEASVMKEFNCHHVVRLLGVCSRGQPMYVVMEMMTYGDLKSYLRSRRP

NEQ--EHVRG-DSQTMLLQR---MACEIAAGLAAMHKLHFLHSDLALRNCYLTSDLNVKVGDYGIGFSRYKEDYIETDDKKVFPLRWTAPELVTSFQDRL
 |.  . ..    . . |..   || ||. |.|    . | | ||| |||    |. ||.|| |     |  ||     |   | || |||   |  |  
EEEFNNPGCNRNQHVPCLDQMHQMAAEICDGMAYLAAKKFVHRDLACRNCMVNHDFTVKIGDFGMTRDIYEHDYYRKGGKGMLPVRWMAPE---SLKDGV

LTADQTKYSNIWSLGVTLWELFNNAAQPYANLSDLDVLNQVIRERDMKLPKPQLEQPY--SDRWYEVLQFCWLP-PDKRPAAEDVHRLLTY
 |.    .| .||.|| |||    ..|||  ||   ||. . ... .      |..|   ...|.|. . ||   |  || . |.  .|  
FTT----HSDVWSFGVVLWEMVTLGEQPYQGLSNEQVLKYIGMDGNV------LRPPENCPEYWQELMMMCWQYQPKMRPTFLDIIHYLCD
Kinase LMR2.AA Frk 136-409 29 4.6e-29 97.64 In-house 1-260 (260) Show / Hide 
Range on Protein: 136-409
Range on HMM: 1-260/260
Sequence Identity: 29% (81 aa)

LNYIQEIGSGWFGKVLLGETYTGTSVARVIVKELKV-SASPKEQDTFLKSGEPYYILQHPNVLQCVGQCVEAIPYLLVFEFCDLGDLKAYLHNEQEHVRG
. .|...||| ||.|  |     | ||   ||.||  .. |..   ||.       |.|| ..|    |    | ... |    | |. ||   ... | 
IQLIRRLGSGQFGEVWEGLWNNTTPVA---VKTLKPGTMDPND---FLREAQIMKKLRHPKLIQLYAVCTVEEPIYIITELMRHGSLQEYLQAINDKGR-

DSQTMLLQRMACEIAAGLAAMHKLHFLHSDLALRNCYLTSDLNVKVGDYGIGFSRYKEDY--IETDDKKVFPLRWTAPELVTSFQDRLLTADQTKYSNIW
  |   |  ||  .|||.| . .  ..| ||| ||  .  .. .|. |.|.     |..    |.     ||..||||| .        .   |  | .|
QCQMQQLVDMAAQVAAGMAYLESQNYIHRDLAARNVLVGEHNICKIADFGLARVLMKDNEDIYESRHGARFPIKWTAPEAAN-------YNKFTIKSDVW

SLGVTLWELFNNAAQPYANLSDLDVLNQVIRERDMKLPKPQLEQPYSDRWYEVLQFCW-LPPDKRPAAEDVH-RLLTYL
| |. | |.      ||. . . .||..|  ... ..|.|   ..   . ||... ||   |.|||  | .. .|  |.
SFGILLTEIITYGRMPYPGMTNAEVLQMV--DHGYRMPQPPNCPQ---QLYEIMLECWHSDPMKRPTFETLQWKLEDYF
Kinase LMR2.AA Fer 136-407 24 3e-28 93.39 In-house 1-283 (283) Show / Hide 
Range on Protein: 136-407
Range on HMM: 1-283/283
Sequence Identity: 24% (74 aa)

LNYIQEIGSGWFGKVLLGE-----TYTGTSVA---RVIVKELKVSASPKE-QDTFLKSGEPYYI-LQHPNVLQCVGQCVEAIPYLLVFEFCDLGDLKAYL
 . .  .|.| ||.| .|.        ...|     | || .| ... || .  |..        ..|||| .. | ||   |...|.|||. |.|. ||
VTLGKKLGEGAFGEVYKGRRTLKCKKGKWHVVNKVAVKVKKCKCEDATKEQIKEFMHEARIMRNNYDHPNVVKFYGVCVDEQPIMIVMEFCNGGSLDSYL

HNEQEHVRGDSQTM-LLQRMACEIAAGLAAMHKLHFLHSDLALRNCYLTS-DLNVK--VGDYGIGFS--RYKEDYIETDDKKVFPLRWTAPELVTSFQDR
  ...     . ..  . ||. ..|.|.. .|. . .| |.| ||| ..  ....|  . | |      .|..|| . .  .  | ||.||| ....   
KKNKNK----TVSDNEKIRMCYQAACGMEYLHSKNCIHRDIAARNCLYHKDKVKKKCKISDFGMSRQCSDYGYDYKMKEKACKVPIRWLAPETWQTG---

LLTADQTKYSNIWSLGVTLWELFNNAAQPYAN------LSDL--DVLNQVIR-ERDMKLP--KPQLEQPYSDRWYEVLQ-FCWL-PPDKRPAAEDVHRLL
      .. . .|| ||..|| |.|.|.||..      .  .  .   ..|. .. |..|   |       .. ....   ||   |..|| . .... |
----IYSPKTDVWSFGVMCWEIFTNGAEPYPGQPHGMKMTNVKKQARKWIIKKGYMMPMPNHMP-------PEIMQIMMKQCWQKDPEDRPTMKEICQKL

T
 
K
Kinase LMR2.AA DDR 136-406 25 4.1e-28 95.13 In-house 1-306 (306) Show / Hide 
Range on Protein: 136-406
Range on HMM: 1-306/306
Sequence Identity: 25% (80 aa)

LNYIQEIGSGWFGKVLLGETYTGT------SVAR--------VIVKELKVSASPKEQDTFLKSGEPYYILQ-HPNVLQCVGQCVEAIPYLLVFEFCDL-G
|.    ||.| || | | |.  .       .           | || |.  |.      |.|       .  |||.   || |..  ||... |.    |
LIFVEKIGEGQFGEVHLCEVEGMQDYIEFDFHCDVHKGHPTLVAVKMLRPDACKHARNDFHKEIKCMSQCKRHPNIVRLVGVCTQDEPYCMIMEYMENLG

DLKAYLHNEQ------EHVRGDS--------QTMLLQRMACEIAAGLAAMHKLHFLHSDLALRNCYLTSDLNVKVGDYG--IGFSRYKEDYIETDD----
||. ..   .      . ...|         ..  . ...  ||.|..    . | | ||| |||    ....|. | |  .  . |  ||   .     
DLNQFWMEHEAENSGLMNCKADTQNCQKPTISYECCVYICTQIASGMKYLESMNFVHRDLATRNCLVGKEYHIKICDFGTVMSRNLYSQDYYRVEGFTGR

-KKVFPLRWTAPELVTSFQDRLLTADQTKYSNIWSLGVTLWELFNNA-AQPYANLSDLDV---LNQVIRERDMK--LPKPQLEQPYSDRWY-EVLQFCW-
 . . |.|| |.| .       |    |  | .|. |||.|| |  . .|||  |.| .|   . .  |.  |.  ||.| .     .  | . .  || 
QRHHMPIRWMAWESI-------LLGKFTTKSDVWAFGVTMWEMFMFCREQPYEQLTDEQVIENACEFFRHQGMQVYLPMPPM---CPYEIYNQLMCRCWR

LPPDKRPAAEDVHRLL
  . .||  | .|..|
RDQSQRPSFEEIHKFL
Kinase LMR2.AA TKL 142-406 17 2.4e-26 91.89 In-house 1-364 (364) Show / Hide 
Range on Protein: 142-406
Range on HMM: 1-364/364
Sequence Identity: 17% (66 aa)

IGSGWFGKVLLGETYT---------GTSVARVIVKELKVSASPK-----------------------EQDTFLKSGEPYYILQHPNVLQCVGQCVEAIP-
|||| ||.|  |.            |. ||  . |.  .. . |                       ..... .       |.|||..|..| | .  . 
IGSGGFGEVYKGKWRGWGGKCPSDTGKDVAVKKFKSHNDDEFTKNSQENNDNNNYSDMQLNDPEASWFRFFEEEEIMMMSRLRHPNIVQFMGYCCCPPCG

------------YLLVFEFCDLGDLKAYLHNEQEHVRGDSQTMLLQRMACEIAAGLAAMHKLH--------FLHSDLALRNCYLTSDLN-----------
            . .| |.|. |.|  |||             .. |.| .|| |.. .|  .         .| ||  .|. . ....           
CVCMHPVGPWGQLCIVMEYCPGGSLLHYLH-----------WHQRCRWALDIARGMNYLHSMNPKWCTKPPIIHRDLKSKNILVDENWTNVSNYMYNPNA

---VKVGDYGIGFSRYKEDYIETDDK-------------------KVFPLRWTAPELVTSFQDRLLTA---------DQTKYSNIWSLGVTLWELFNNAA
   .|..|.|  .|| ..   .  |                    ..  .|| |||.    ..    .         . .. . ..| |. |||..    
DWCCKICDFG--LSRFMSQSGNMNDTMTTMMESAEHQNNRKTTMTQCGTPRWMAPEVLRGQMNYTEKVGIDEFCKGFEYSEKCDVYSFGIVLWEILTRCR

QPYANLSDLDVL--------NQVIRERDMKLPKP---------QLEQPYSDRWYEVLQFCWLP-PDKRPAAEDVHRLL
 ||...   ...          .. .. ...| |         . . .  ... . .| || . |.||| ....   |
-PYYDYPYMPMIFQDPFEEMFMMVCDKGLRPPIPPIWQNHHKMCPCPDCPPSMKKLMQDCWDHDPEKRPSFQEILKRL
Kinase LMR2.AA S_TKc 136-409 18 2.5e-17 64.8 SMART 1-231 (231) Show / Hide 
Range on Protein: 136-409
Range on HMM: 1-231/231
Sequence Identity: 18% (54 aa)

LNYIQEIGSGWFGKVLLGETYTGTSVARVIVKELKVSASPKEQDTFLKSGEPYYILQHPNVLQCVGQCVEAIPYLLVFEFCDL--GDLKAYLHNEQEHVR
   ...||.| |||| ..      .  .| .|..|     .| .   |        .|||. .. . ...   . .|.|.||   |||. |... . | .
YEILRKIGKGAFGKVYKCRHKK--TGRIVAIKIIK-EHIRREIQILKK--------HHPNIVKLYDVFQD-DHLYMVMEYCDGDLGDLFDYIKKRGRHGL

GDSQTMLLQRMACEIAAGLAAMHKLHFLHSDLALRNCYLTSDLNVKVGDYGIGFSRYKEDYIETDDKKVFPLRWTAPELVTSFQDRLLTADQTKYSN---
.   .   ......|. .|. .|.....| ||   |  |..  ..|..|   |..|         .  .  . . |||..             .|.    
RFPFPEHARFYMYQICCALEYCHSHGIIHRDLKPENILLDE--HIKICDF--GLARQL-------TTFCGTPWYMAPEVL-------------GYGKCKC

-IWSLGVTLWELFNNAAQPYANLSDLDVLNQVIRERDMKLPKPQLEQPYSDRWYEVLQFCWL-PPDKRPAAEDVHR------LLTYL
 .||.|..|.|..     |.    ..... ..|.               |.   . .. |.   |.||| | .. .      .  ..
DWWSCGCILYEMLC-GYPPFP---QMQMMFKKIG---------------SPEAKDFIRKCLQKDPEKRPTA-EALQDEWDIKCHPWF
Kinase LMR2.AA Pkinase 136-285 22 1e-06 24.37 Pfam 1-158 (293) Show / Hide 
Range on Protein: 136-285
Range on HMM: 1-158/293
Sequence Identity: 22% (37 aa)

LNYIQEIGSGWFGKVLLGETYTGTSVAR---VIVKELKVSASPKEQDTFLKS-GEPYYI--LQHPNVLQCVGQCVEAIPYLLVFEFCDLG----DLKAYL
.  .. |||| ||.|     | .. .     | ||..|..   ...|  .    | ..   |.|||.... . . .   . .|.|.|. |    ||..|.
YHIGRKIGSGSFGCV-----YKCHHKGTGKIVAVKIIKKRHEKSWKDQTHRRLSEIQIMKRLNHPNIVRLYDWFEDKDHIYMVMEYCEGGLYVMDLFDYI

HNEQEHVRGDS--QTMLLQRMACEIAAGLAAMHKLHFLHSDLALRNCYLTSDLNV----KVGDYGI
.    . .|    .   ..... .|. ||. .|.  ..| || . |. . .. ..    |..| |.
ST---WRHGCFYFSEWECKFYMYQILRGLEYCHSMGIIHRDLKPENILIDNNGHIDACVKICDFGL
Kinase LMR2.AA Pkinase 331-409 14 0.212308 6.03 Pfam 195-261 (293) Show / Hide 
Range on Protein: 331-409
Range on HMM: 195-261/293
Sequence Identity: 14% (12 aa)

IWSLGVTLWELFNNAAQPYANL----SDLDVLNQVIRERDMKLPKPQLEQPYSDRWYEVLQFCWLPPDKRPAAEDVHRLLTYL
.||.|..|.|...    |. .     . .| . |.|... .. .. . ....| .... ... | .        . |... ..
MWSCGCILYEMLCGR-PPFPGHCWHDN-HDQM-QMICRIMGPPLHFDWPWWCSISYFF-FRH-W-H--------F-HWTF-HN