Gene MAP3K7 (Mouse)

MAP3K7

Species: Mouse
Alias: MAP3K7
External Links: Entrez Gene , Refseq cDNA , Refseq Protein , Phosphosite , iHOP
Annotation:

Classification

Group: STE
Family: STE11
Subfamily: ASK

Sequence

Name Sequence Type Origin Length Description Download
MAP3K7.kin_dom Protein Kinase Domain Sugen global kinase HMM prediction 260 Kinase domain by global Sugen HMM Fasta, JSON
MAP3K7.NA RNA Sugen 4348 None Fasta, JSON
MAP3K7.AA Protein Sugen 1331 None Fasta, JSON

Protein domain

Protein domains of MAP3K7.AA. The domains are annotated by HMM profiles from Pfam and SMART, as well as in-house data which includes HMMs of each individual kinase group, family and subfamily. Here is domain list in details, including sequence identity, significance and alignment. In particular, you can find can find the best hit kinase group/family/subfamily, which is helpful to understand the relationship between kinases.Kinase domain and best hit kinase group/family/subfamily are highlighted in red and blue. Visualized by pviz.

Usage: Zoom in selected region by dragging mouse and zoom out by double-clicking.

Show/hide domain list
Domain Protein name Domain Name Range Identity (%) Significance Score Profile Source Profile Range (length) Alignment
ASK_nterm_v5 MAP3K7.AA ASK_nterm_v5 106-160 65 7.1e-33 115.54 In-house 1-55 (55) Show / Hide 
Range on Protein: 106-160
Range on HMM: 1-55/55
Sequence Identity: 65% (36 aa)

PFGELDFGETAVLDAFYDADVAIVDMSDISRQPSLFYHLGVRESFDMANNVILYY
.|..||||||...| || |||.|||||.  .||.||||||||.||.|.||.|||.
EFMRLDFGETDMFDEFYNADVVIVDMSIDHQQPNLFYHLGVRHSFKMRNNIILYC
TPR_ASK_1 MAP3K7.AA TPR_ASK_1 286-319 52 5.4e-20 65.95 In-house 1-38 (38) Show / Hide 
Range on Protein: 286-319
Range on HMM: 1-38/38
Sequence Identity: 52% (20 aa)

SDIIINLLLSYRDIQDYDAMVKLVETLK---MLPTC-D
.||..|...|||||||||.|..|||.||    .|.| .
GDIVHNFMHSYRDIQDYDSMIELVEDLKEGEHIPNCCK
TPR_ASK_2 MAP3K7.AA TPR_ASK_2 362-404 58 2.3e-29 92.82 In-house 1-46 (46) Show / Hide 
Range on Protein: 362-404
Range on HMM: 1-46/46
Sequence Identity: 58% (27 aa)

PDMFCLCGRIYKDIFLDSGCEE---DASRDSAIEWYRKGFELQSSL
|||.|.|||||||.||.|....    .|||.||.|||||||.| ..
PDMWCMCGRIYKDMFLESQYTDEAARESRDQAIHWYRKGFEIQPNH
TPR_ASK_3 MAP3K7.AA TPR_ASK_3 450-483 58 2.1e-14 53.19 In-house 1-34 (34) Show / Hide 
Range on Protein: 450-483
Range on HMM: 1-34/34
Sequence Identity: 58% (20 aa)

YWDVGQFFTVSMLASDIGKAVQAAERLFKLKPPV
||||. || .| || |  |..||.| .||||||.
YWDVATFFEISILACDYHKCMQACECMFKLKPPN
Kinase MAP3K7.AA ASK 661-912 85 4.2e-193 647.82 In-house 1-254 (254) Show / Hide 
Range on Protein: 661-912
Range on HMM: 1-254/254
Sequence Identity: 85% (216 aa)

VLGKGSYGIVYAGRDLSNQVRIAIKEIPERDIRYSQPLHEEIALHKYLKHRNIVQYLGSVSENGYIKIFMEQVPGGSLSALLRSKWGPMK--EPTIKFYT
|||||.|||||||||...||||||||||||| ||.|||||||||||.|.|||||||||..|||||.||||||||||||||||||||||||  | |..|||
VLGKGTYGIVYAGRDMHTQVRIAIKEIPERDSRYVQPLHEEIALHKQLRHRNIVQYLGCCSENGYFKIFMEQVPGGSLSALLRSKWGPMKDNENTMNFYT

KQILEGLKYLHENQIVHRDIKGDNVLVNTYSGVVKISDFGTSKRLAGINPCTETFTGTLQYMAPEIIDQGPRGYGAPADIWSLGCTIIEMATSRPPFHEL
|||||||||||||||||||||||||||||||||||||||||.|||||||||||||||||||||||.||||.||||.||||||.|||..||||..||||||
KQILEGLKYLHENQIVHRDIKGDNVLVNTYSGVVKISDFGTCKRLAGINPCTETFTGTLQYMAPEVIDQGQRGYGKPADIWSFGCTMVEMATGKPPFHEL

GEPQAAMFKVGMFKIHPEIPEALSAEARAFILSCFEPDPQKRVTAADLLQEGFL
||||||||||||.|.||||||.||||...|||.||||||.||..|.||||..||
GEPQAAMFKVGMYKKHPEIPEELSAECKNFILRCFEPDPCKRASAQDLLQDPFL
Kinase MAP3K7.AA STE11 656-912 43 3.9e-162 544.92 In-house 1-303 (303) Show / Hide 
Range on Protein: 656-912
Range on HMM: 1-303/303
Sequence Identity: 43% (133 aa)

NGERVVLGKGSYGIVYAGRDLSNQVRIAIKEIPERDIR--------YSQP------LHEEIALHKYLKHRNIVQYLG-SVS--ENGYIKIFMEQVPGGSL
  .. ..|||..| ||...........|.|.|......        . |.      ..|||.|.| |.| |||.|.| ...  .|....||||..|||||
WQKGEIIGKGAFGTVYKCMNVDTGELMAVKQIEIQNNNQMKEDQEKEYQSHKMHKAIQEEIKLMKHLNHKNIVRYYGCCLHDNQNDHVNIFMEYCPGGSL

SALLRSKWGP--MKEPTIKFYTKQILEGLKYLHENQIVHRDIKGDNVLVNTYSGVVKISDFGTSKRLAGINPCTET----------FTGTLQ--------
|..||.||||  . |..|..|||||||||.|||...|.||||||.|.|......|.|..|||..||||.|..||..          .|||..        
SSMLRHKWGPMKFDEMVIRKYTKQILEGLQYLHSHGIIHRDIKGANILLDSDGNVCKLADFGCAKRLAWICTCTHNMNMTQNHCKSMTGTPYNSMMGTPM

YMAPEIIDQGPRG-YGAPADIWSLGCTIIEMATSRPPFHELGE-PQAAMFKVGMF-KIHPEIPEALS------AEARAFILSCFEPDPQKRVTAADLLQE
.||||.|.|..|. ||..|||||||||.||||| .||.|.... ..|||||.||. | ||.||| .|      .|.|.|.. |||.||.|| ||..||| 
WMAPEVIKQEGRDGYGRKADIWSLGCTVIEMATGKPPWHNYDHNHMAAMFKIGMGHKPHPPIPEHMSPISWISEECRDFLRHCFEHDPKKRPTANQLLQH

GFL
 |.
PFI
Kinase MAP3K7.AA STE 657-912 27 5e-105 355.23 In-house 1-359 (359) Show / Hide 
Range on Protein: 657-912
Range on HMM: 1-359/359
Sequence Identity: 27% (102 aa)

GER-VVLGKGSYGIVYAGRDLS---------------NQVRIAIKEIPERDI-----------------RYSQPLHEEIALHKYLK--HRNIVQYLGSVS
 |.  ..|||..| || ...                 .....|||... ..                     | . .|| ..| ..  | |||.|.|.  
WEGIEKIGKGAFGTVYKAMNHKNCNIHKTGEVENNGETGEIMAIKQMNLENCNNKDENQENQELENKNHEEMQQILKEIKIMKKCNHMHPNIVKYYGCYF

ENG-------YIKIFMEQVPGGSLSALLRSKWGPMK-------------EPTIKFYTKQILEG-LKYLHENQIVHRDIKGDNVLVNTYSGVVKISDFGTS
 .|       .. |.|| ..||||. ....|.|. |             |. |.....|||.| |.|||...|.|||||..|.|.      ||..|||..
KEGHNHKNDDELWICMEYMDGGSLDDIIKHKYGCGKPLNHNRQHQHRFPESQIAYICRQILKGLLYYLHSHHIIHRDIKPANILL------VKLCDFGVC

KRLAGINP----------------CTETFTGTLQYMAPEIIDQGPRG----YGAPADIWSLGCTIIEMATSRPPF---HELGEPQAAMFKVGMF------
..|. ...                 . ||.||  .||||.|.|. .|    |.. .|||||||||||||| .||.   | .    ...|. .|.      
GQLTDSMANIQSNNIIDCIETMQQKRNTFVGTP-WMAPEVIQQNGQGRDKGYDTKCDIWSLGCTIIEMATGKPPWHDMHPMRAMFMIPFNYHMQQQFEQL

----KIHPEIPE-------------------ALSAEARAFILSCFEPDPQKRVTAADLLQ--EGFL
    . .| .|.                    .| | . ||  |.. ||.|| || .||.    |.
CIVNGPPPPLPDHLSQNEMISYGGSGTTYPHKWSPEFKDFINKCLQKDPNKRPTASQLLKSEHPFI
Kinase MAP3K7.AA STE11-Unclassified 659-912 35 4.6e-94 318.82 In-house 4-308 (308) Show / Hide 
Range on Protein: 659-912
Range on HMM: 4-308/308
Sequence Identity: 35% (110 aa)

RVVLGKGSYGIVYAGRDLSNQVRIAIKEIPERDIR-----YSQP----LHEEIALHKYLKHRNIVQYLGSV--SENGYIKIFMEQVPGGSLSALLRSKWG
. ..||||.| || . ....   .|.|.| . |.        .     . .|... | | | |||||.|     ... | ||||..||||....|. | |
GEFIGKGSFGQVYKCMNCNTGEFMAVKQIEIHDYNSQQEDMQKEMIQSIQKEMKVLKQLNHKNIVQYYGCEIHKHEDCINIFMEYMPGGSIWSMLN-KYG

PMKEPTIKFYTKQILEGLKYLHENQIVHRDIKGDNVLVNTYSGVVKISDFGTSKRLA------------------GIN-PCTE------TFTGTLQ---Y
.  |..|| |||||||||.|||.. |.||||||.|.|. .  |..|..|||..|  .                   |  .  .      .  ||..   .
CFDEMVIKKYTKQILEGLAYLHSHGIIHRDIKGANILIDF-DGICKLTDFGCAKQIEFDRTRTVRMNKIQNFDHYKICQHINSQQNHCKSMQGTPYQPFW

MAPEIID---QGPRGYGAPADIWSLGCTIIEMATSRPPFHELGE--PQAAMFKVGMFKIHPEIPEALS-----------AEARAFILSCFEPDPQKRVTA
||||.|.   |.  |... .||||||||.||||| ..|.  . .  ...|..|..| .  |.||| ||           .|...|.  ||. ||.|| ||
MAPEVIKNSTQT--GHCRKSDIWSLGCTVIEMATGKHPWSNCQNDNFMWAIMKIVMSNQIPQIPEHLSPVCDFISCWISQECKDFLRKCFQIDPKKRPTA

ADLLQEGFL
  |||  |.
NQLLQHPFI
Kinase MAP3K7.AA S_TKc 656-912 30 1.4e-89 304.85 SMART 1-231 (231) Show / Hide 
Range on Protein: 656-912
Range on HMM: 1-231/231
Sequence Identity: 30% (83 aa)

NGERVVLGKGSYGIVYAGRDLSNQVRIAIKEIPERDIRYSQPLHEEIALHKYLKHRNIVQYLGSVSENGYIKIFMEQVPG--GSLSALLRSKWGP-----
     ..|||..| || .|. . . . |||.|.       . .  ||...|  .| |||.....  . ... ..|| ..|  |.|  ..... ..     
YEILRKIGKGAFGKVYKCRHKKTGRIVAIKIIK-------EHIRREIQILKK-HHPNIVKLYDVFQD-DHLYMVMEYCDGDLGDLFDYIKKRGRHGLRFP

MKEPTIKFYTKQILEGLKYLHENQIVHRDIKGDNVLVNTYSGVVKISDFGTSKRLAGINPCTETFTGTLQYMAPEIIDQGPRGYGA-PADIWSLGCTIIE
. | ...||..||...|.|.|...|.|||.| .|.|...   ..||.||| ...|        || ||. |||||..     |||  ..|.||.||...|
FPE-HARFYMYQICCALEYCHSHGIIHRDLKPENILLDE---HIKICDFGLARQL-------TTFCGTPWYMAPEVL-----GYGKCKCDWWSCGCILYE

MATSRPPFHELGEPQAAMFKVGMFKIHPEIPEALSAEARAFILSCFEPDPQKRVTAADLLQ-------EGFL
|.. .|||.     ...|||. .           | ||. ||  |.. ||.|| || ..||         ..
MLCGYPPFP----QMQMMFKKIG-----------SPEAKDFIRKCLQKDPEKRPTA-EALQDEWDIKCHPWF
Kinase MAP3K7.AA Pkinase 661-912 30 5.7e-81 280.1 Pfam 6-293 (293) Show / Hide 
Range on Protein: 661-912
Range on HMM: 6-293/293
Sequence Identity: 30% (90 aa)

VLGKGSYGIVYAGRDLSNQVRIAIKEIPERDIRYSQPLHE----EIALHKYLKHRNIVQYLGSVSENGYIKIFMEQVPGG----SLSALLR-SKWGPM--
..|.||.| || ... ... . |.|.|. |... ... .     ||...| |.| |||...... ....| . || ..||    .|..... .. |..  
KIGSGSFGCVYKCHHKGTGKIVAVKIIKKRHEKSWKDQTHRRLSEIQIMKRLNHPNIVRLYDWFEDKDHIYMVMEYCEGGLYVMDLFDYISTWRHGCFYF

KEPTIKFYTKQILEGLKYLHENQIVHRDIKGDNVLVNTYSGVV----KISDFGTSKRL-AGINPCTETFTGTLQYMAPEIIDQGPRGYGAPADIWSLGCT
 | ..||| .|||.||.|.|.. |.|||.| .|.|..   |..    ||.||| .| .    |. . ||.||. |||||.|  | ..|| ..|.||.||.
SEWECKFYMYQILRGLEYCHSMGIIHRDLKPENILID-NNGHIDACVKICDFGLAKQFDY-NNS-MTTFCGTPWYMAPEVIR-GGQYYGPKVDMWSCGCI

IIEMATSRPPFHEL-----GEPQAAMFKVGMFKIHPEIPEALS-------------------AEARAFILSCFEPDPQKRVTAADLLQEGFL
..||.. |||| .       .... ...... ..| ..|.  |                    |.. || .|...||.|| ||...||  ..
LYEMLCGRPPFPGHCWHDNHDQMQMICRIMGPPLHFDWPWWCSISYFFFRHWHFHWTFHNWSEECKDFIKWCLCKDPKKRPTAEQILQHPWF
Kinase MAP3K7.AA MEKK15 655-912 42 2e-70 240.26 In-house 2-264 (264) Show / Hide 
Range on Protein: 655-912
Range on HMM: 2-264/264
Sequence Identity: 42% (116 aa)

ANGERVVLGKGSYGIVYAGRDLSNQVRIAIKEIPERDIRYSQP------LHEEIALHKYLKHRNIVQYLGSVSENGYIKIFMEQVPGGSLSALLRSKWGP
  |.  .|||| || || |     |. ||.| .   .|   .       | ||. | | |||.||| |||   |.  . |||. |||||.|...  ..||
KKGN--ILGKGAYGTVYCGLTNTGQL-IAVKQVELDEIDKEKAKQQYRKLQEEVDLLKTLKHKNIVAYLGVCLEDNVVNIFMQFVPGGSISSII-NRFGP

MKEPTIKFYTKQILEGLKYLHENQIVHRDIKGDNVLVNTYSGVVKISDFGTSKRLA--GINPCT----ETFTGTLQYMAPEIIDQGPRGYGAPADIWSLG
. |     ||||||.| .||||| .||||||| ||..    |..|. |||  |||.  |||           ||  .||||.|     |||  .||||.|
LDEMVFCKYTKQILQGVQYLHENCVVHRDIKGNNVMLMP-TGIIKLIDFGCAKRLCWQGINRTHSDMLKSMRGTPYWMAPEVIME--TGYGRKSDIWSIG

CTIIEMATSRPPFHELGEPQAAMFKVGMF-KIHPEIPEALSAEARAFILSCFEPDPQKRVTAADLLQEGFL
||. |||| .||. .. .. |||| .|    . |..|.  | .|| |.  |   | . | || .||.  |.
CTVFEMATRKPPWADM-DRMAAMFYIGAHRDPMPQLPVKFSEDARMFVRMCLTRDQHERPTASQLLKHPFI
Kinase MAP3K7.AA CAMK 661-912 17 3.4e-64 205.49 In-house 1-425 (425) Show / Hide 
Range on Protein: 661-912
Range on HMM: 1-425/425
Sequence Identity: 17% (73 aa)

VLGKGSYGIVYAGRDLSNQ------------VRIAIKEIPERDIRYS----------------------------QPLHEEIALHKY-------LKHRNI
.||.||.|.|. ... ...            .. ||| |. . .. .                            . .  ||...|        |.|.||
TLGRGSFGKVKLCIHKNTTGKERVHHIYTNGQKVAIKIIDKKKLKDKQNQDYSNCYKIDKSKCKHRYCWRRPKDRKNVRREIEIMKKLQGIGNKLDHPNI

VQYLGSVSENGY-------------------IKIFM---EQVPGG----SLSALLRSK--------------WGPMKEPTIKFYTKQILEGLKYLHENQI
.. .     . |                   . ..|   | ..||     |   ....              .| ..|   ..| .||.....|.|.. |
IKLYEVYEDPHYFKNTNDYETSKQVFTKDKHMYMVMEIMEYCSGGELFDDLFDYIVEHGCYGEEFDQFDIVERGRFTEREARRYFRQICSAVHYCHSHNI

VHRDIKGDNVLVNTYS----------------GVVKISDFGTSKRLAGI-----------------------NPCTETFTGTLQYMA-PEIIDQGP----
||||.| .|.|... .                . .||.||| .... .                        ..  .|| ||. ||| ||.. . .    
VHRDLKPENILLDDNNDDSDPVEHDEIFDWNNNNIKIIDFGFANKFDPGENNFMCSDYKGGEMHNQWTTPTEGQKMKTFCGTPEYMAAPEVLNGKGHCNM

--------RGYGAPADIWSLGCTIIEMATSRPPFHELGEPQAA--------------MFKVGMFK-IHPEIPE-------------------ALSAEARA
        ..|| ..|.||.|.    | . .||| .  . .                . . | .  ..|....                    .|.|.. 
QNATDEEKPYYGPKCDMWSCGVILYIMLCGYPPFYGDCDNEICEDEWIGMNDYELFEKIMKGKYDFPPPYFSPISCNYGPEWWDDISDEFHHFVSQECKD

FILSCFEPDPQKRVTAADLLQEGFL
.| .. ..||.|| |... |.  ..
LIRKMLQVDPEKRMTIEQCLNHPWM
Kinase MAP3K7.AA MEKK2 658-912 40 7.9e-64 218.37 In-house 3-262 (262) Show / Hide 
Range on Protein: 658-912
Range on HMM: 3-262/262
Sequence Identity: 40% (108 aa)

ERVVLGKGSYGIVYAGRDLSNQVRIAIKEIPERD-----IRYSQPLHEEIALHKYLKHRNIVQYLGSVSENG--YIKIFMEQVPGGSLSALLRSKWGPMK
   .||.| .| ||   |      .|.| ..  .      .  | |. || | | |.|  |||| | . .|.   . |||| .||||.   |.  .|.. 
RGKLLGQGAFGRVYVCYDVDTGRELAVKQVQFDPDNPETRKEVQALECEIQLLKNLQHERIVQYYGCLRDNQEKTLSIFMEYMPGGSVKDQLKA-YGALT

EPTIKFYTKQILEGLKYLHENQIVHRDIKGDNVLVNTYSGVVKISDFGTSKRLAGINPCT---ETFTGTLQYMAPEIIDQGPRGYGAPADIWSLGCTIIE
|   . ||.|||||..|||.. |||||||| |.| .  || ||..||| ||||  |        . |||  .|.||.|.    |||  ||.||.|||..|
ETVTRKYTRQILEGMHYLHDHMIVHRDIKGANILRDS-SGNVKLGDFGASKRLQTICMHITGMKSVTGTPYWMSPEVING--EGYGRKADVWSIGCTVVE

MATSRPPFHELGEPQAAMFKVGMFKIHPEIPEALSAEARAFILSCFEPDPQKRVTAADLLQEGFL
| | .||. |  |  ||.||.   .  |..|. .| .|| |.  ||    | |  |..||.  | 
MLTEKPPWAEY-EAMAAIFKIATQPTNPQLPQHVSQHARDFLKRCFVEIKQDRPSAEELLRHHFV
Kinase MAP3K7.AA STE20 661-912 35 3.5e-61 209.57 In-house 6-288 (288) Show / Hide 
Range on Protein: 661-912
Range on HMM: 6-288/288
Sequence Identity: 35% (100 aa)

VLGKGSYGIVYAGRDLSNQVR----IAIKEIPERDI----RYSQPLHEEIALHKYLKHRNIVQYLGSVSEN----GYIKIFMEQVPGGSLSALLRS--KW
..|.|||| || ... ...      .||| .. ..        . .  ||   | .|| |||.|.||   .      . | ||   ||||. ...   |.
KIGQGSYGKVYKAYHKPTGEYCNQRVAIKKMNLEKCDNEQDEWEDIQKEISIMKQCKHPNIVKYYGSYLKDDTCDDELWIVMEYCGGGSLTDIMKHCMKC

G------PMKEPTIKFYTKQILEGLKYLHENQIVHRDIKGDNVLVNTYSGVVKISDFGTSKRLAG-----INPCTETFTGTLQYMAPEIIDQGP---RGY
|      ||.|. | . ....|.||.|||.|.|.|||||.||.|... .| ||..||| .  |       ...   || ||  .||||.| .      ||
GKNHKGHPMNEEQIAYICREVLQGLDYLHSNHIIHRDIKADNILLTE-DGEVKLADFGVCAQLTKHGRDTMQFKRNTFVGTPYWMAPEVIQCMEGPDKGY

GAPADIWSLGCTIIEMATSRPPFHELGEPQAAMFKVGMFKIHP---EI--PEALSAEARAFILSCFEPDPQKRVTAADLLQEGFL
.  .|||||| |.||||. .||....  |  |||..   .  |   .   |.  | | . |. .| . ||.|| || .||.  |.
DYKCDIWSLGITAIEMAEGEPPYFDM-HPMRAMFMIPKNQNPPPTLKDDKPHKWSPEFHDFVDKCLQKDPEKRPTASQLLKHPFI
Kinase MAP3K7.AA Ciliate-E2 661-912 21 1e-56 193.18 In-house 6-365 (365) Show / Hide 
Range on Protein: 661-912
Range on HMM: 6-365/365
Sequence Identity: 21% (79 aa)

VLGKGSYGIVYAGRDLSNQVR-----------------------IAIKEIPERDIRYSQP-LHEEIALH------------KYLKHRNIVQYLGSVS--E
..|.|..|.|| ... ..| .                       .|.| . ...|..    .|.   ..            . |.| ||...  .     
KIGQGNFGSVYKCKVWKVQKQFAIKIIDQKQQRQQMQEKVKIKIYAMKIMKKNQIEQIKQEIHIMREINCFYKKINEKNILEQLNHPNIIKMYECFQEKD

NGYIKIFMEQVPGGSLSALLRSKW----------GPMKEPTIKFYTKQILE---------------GLKYLHENQ-IVHRDIKGDNVLVNTYSGVVKISD
. .| . || . ||.|  ......          ....|  ||...||||.               .|.|||..  |.||||| .|.|.      .||.|
DNNIYLVMEYCQGGDLFDYIKNNKKKRNHEIEKDKYFTEKEIKYIMKQILQGFKTKAEFYIACIILALEYLHSKNNIIHRDIKPENILF------IKIID

FGTSKRLAGINP-------------------------------CTETFTGTLQYMAPEIIDQGP-------RGYGAPADIWSLGCTIIEMATSRPPFHEL
||.||..   |                                 . |. ||. ||||||.  ..        ||.  .||||||... || . .|||   
FGLSKKYDDDNQNRTHKQQCKWYMFKNDTSRTPGYMDQIIQQNMFNTICGTPGYMAPEILNGKKYDNQQKQKGYDYKCDIWSLGVILYEMLFGKPPF---

GEPQAAMFKVGMFKIHPE--------------IPEALSAEARAFILS----CFEPDPQKRVT-AADLLQEGFL
        | . ... ..              ... .| |.  .|      ... ||.|| | . ..|.  ..
----QQQIKQCKIDFPCPEWQKDTQCIQCKWKSWKKWSQECKDLIKKFGKRMLQKDPEKRITGWEQILNHPWF
Kinase MAP3K7.AA STE-Unique 728-912 27 5.1e-47 162.53 In-house 371-616 (616) Show / Hide 
Range on Protein: 728-912
Range on HMM: 371-616/616
Sequence Identity: 27% (68 aa)

IFMEQVPGGSLSALLRSKWGP--------MKEPTIKFYTKQILEGLKYLHENQ--IVHRDIKGDNVLVNTYS----GVVKISDFGTSKRLAGI-------
||||  ..|.|. .. .  .|        . |  .. ||.|||||| |||  .  |.|||.| .|.. .         |||.|||...... .       
IFMEYCEHGTLQQIIKRCGCPGNPNNLQLFPETEVIWYTYQILEGLEYLHSQHNPIIHRDLKPHNIFCMQDGKGRVCKVKICDFGHATCCQPDHFEKDNN

-------------------------------NPCTETFTGTLQYMAPEII---DQGPRGYGAPADIWSLGCTIIEMATSRPPFHELGEPQA-AMFKVGMF
                               |    .  ||  ||.||.|   .|.  .|.. .|||||||....|..  ||.|...  || .       
SKNSNTWININNNSSTNSTAQQTPMWDLNINNYTMKYCCGTPCYMCPEVINCRNQINNPYDTKVDIWSLGCMCFHMCCGCPPWHQRYHMQAYIEMCIHIH

KIHP-----EIPEALSAEARAFILSCFEPDPQKRVTAADLLQEGFL
.. |     .||. .. | . || .|.|..| .|..|..||. ..|
CQPPQCPIENIPPKCQPEQQQFIEKCLERNPHHRPSAHQLLHHFWL
Kinase MAP3K7.AA Pkinase_Tyr 661-798 29 3.6e-22 75.69 Pfam 6-156 (270) Show / Hide 
Range on Protein: 661-798
Range on HMM: 6-156/270
Sequence Identity: 29% (45 aa)

VLGKGSYGIVYAGRDL----SNQVRIAIKEI-PERDIRY--SQPLHEEIALHKYL-KHRNIVQYLGSVS-ENGY--IKIFMEQVPGGSLSALLRSK---W
.||.|..| || |.      ....  |.| . .  . .   .. . .|... | | .| |||...| .. . .   | | || .|.|.|   ||..    
KLGEGAFGEVYKGTWKGDPDNTKIPVAVKMLKEGAMHEQNCREDFMREAKIMKQLGHHPNIVRLYGVCTDQGEPNQIYIVMEYMPHGDLLDYLRKHREDK

GPMKEPTIKFYTKQILEGLKYLHENQIVHRDIKGDNVLVNTYSGVVKISDFG
.| . ...  .  || .|. ||......|||.   |.||.  ..||||.|||
QPLTMKDLLQMCWQIAKGMEYLESKNCIHRDLAARNCLVTE-NNVVKICDFG
Kinase MAP3K7.AA TyrKc 661-911 24 1.1e-16 46.78 SMART 6-280 (280) Show / Hide 
Range on Protein: 661-911
Range on HMM: 6-280/280
Sequence Identity: 24% (70 aa)

VLGKGSYGIVYAGRDLSNQVRIAIKEIPERDIRYSQPLHEEIALHKYL--KHRNIVQYLGSVSEN-------GYIKIFMEQVPGGSLSALLRSKWGPMKE
.|| | .|.|| |.     .  |.| . |      . ...|. . . |  .| |||. .| ...        . . | || .|.|.|   ||.. .  . 
KLGEGAFGEVYKGTWK---IQVAVKMLKEDA---REDFMREARIMCKLGGHHPNIVRLYGVCTQQGRNFMYIEPLMIVMEYMPHGDLKDYLRKHRPKLCM

PTIKFYTKQILEGLKYLHENQIVHRDIKGDNVLVNTYSGVVKISDFGTSKRLAGI---------NPC----TETFTGTLQYMAPEIIDQGPRG-YGAPAD
..   .  || .|  |||.....|||.   |.||.    .||||||| |. .                    . .   .  |||| |     | .    |
KDLLSFCWQIACGMEYLHSKNCIHRDLAARNCLVGENH-TVKISDFGLSRDIYDDDQQGESKDYYRKKEHKGGKTMLPIRWMAPECI---NYGKFTTKSD

IWSLGCTIIEMATS-RPPFHEL----GEPQAAMFKVGMFKIHPEIPEA-------LSAEARAFILSCFEPDPQKRVTAADLLQEGF
.|| | .. |. |   .|  .      ..| .. .|   .  |  |..        ..|    ...| . || .| | ...  | |
VWSFGVCMWEIFTYGQQPYPGMIQQMMSNQEVIEYVKQGYRMPQPPNDYPMSFVCCPDEMYQIMKQCWHEDPEDRPTFSEI-HECF
Kinase MAP3K7.AA STE-Unique 657-724 28 5.9e-12 38.2 In-house 1-74 (616) Show / Hide 
Range on Protein: 657-724
Range on HMM: 1-74/616
Sequence Identity: 28% (21 aa)

GERVVLGKGSYGIVYAGRDLSNQVRIAIKEIPERDIRYS------QPLHEEIALHKYLKHRNIVQYLGSVSENG
 . . .|.|| | |.  .. ..  | ||| |...  . .      ... .|| ..|.|.| ||| |.|.. ..|
NCQQMIGRGSFGNVHNCQNKKDCFRCAIKVIHLKQFKDFNQEPLVNMIISEIEIMKCLHHQNIVKYYGHWLWGG
Sam7 MAP3K7.AA sam7 1261-1323 22 2.4e-10 34.67 In-house 1-70 (70) Show / Hide 
Range on Protein: 1261-1323
Range on HMM: 1-70/70
Sequence Identity: 22% (16 aa)

GTDRELIDWLQLQGV--DANTIEKIVEEDY----TLSDILNDITKEDLRCLRL-RGGVLCRLWHAVSQHR
 |.... .||.  |   .   .... ....    |  | |  .|.|||. .   |.|  ...|... |.|
WTFEDVCEWLEWIGMENFQQYCDNFRDHGIDDWVTDGDHLCHMTEEDLMEMGITRPGHRKKIWNHIQQMR