Gene MarkmA11 (Mouse)
MarkmA11
Sequence
| Name | Sequence Type | Origin | Length | Description | Download |
|---|---|---|---|---|---|
| MarkmA11.kin_dom | Protein Kinase Domain | Sugen global kinase HMM prediction | 249 | Kinase domain by global Sugen HMM | Fasta, JSON |
| MarkmA11.NA | RNA | Sugen | 1987 | None | Fasta, JSON |
| MarkmA11.AA | Protein | Sugen | 508 | None | Fasta, JSON |
Protein domains of MarkmA11.AA. The domains are annotated by HMM profiles from Pfam and SMART, as well as in-house data which includes HMMs of each individual kinase group, family and subfamily. Here is domain list in details, including sequence identity, significance and alignment. In particular, you can find can find the best hit kinase group/family/subfamily, which is helpful to understand the relationship between kinases.Kinase domain and best hit kinase group/family/subfamily are highlighted in red and blue. Visualized by pviz.
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| Domain | Protein name | Domain Name | Range | Identity (%) | Significance | Score | Profile Source | Profile Range (length) | Alignment |
|---|---|---|---|---|---|---|---|---|---|
| Kinase | MarkmA11.AA | MARK | 28-276 | 51 | 5.1e-160 | 526.58 | In-house | 1-262 (262) | Show / Hide |
Range on Protein: 28-276 Range on HMM: 1-262/262 Sequence Identity: 51% (136 aa) YKVVRTLGHGTYAKVLLAQHRLTGTPVAVKVLL---KNK-PCFQPAMKEANIMKKIKHPNIVSLLQVIE--TKTR-GYLIMELVEGQELYEYIKNS--GH ||...|.|||.|||| ||.|..||. ||.|.. .|. ... | |..||||..||||..|..||| |... |||||...|.|||.|||. |. YKMLKTIGHGSYAKVKLACHKHTGRKVAIKIYEKFKLNDPQWMKNVMREIEIMKKLDHPNIIKLFHVIEQDTEQHQIYLIMEYASGGELYDYIKAHPNGR IEEDEARQIFLQILSAVGYCHGSGIVHRDLKPDNIMIDSKG--SIKIIDFGLSTQVKPGQLLHEHCGAYAFGAPELFLWKSYDGTKSDLWALGVILYYMV ..|.|||.|| ||.||| ||| .|||||.||.||.||..| |||||||.|....|||.| ..||.... |||.||.| |||.| | |.|||.||.|| LHEEEARRIFRQIVSAVNYCHSKNIVHRDIKPENILIDENGNHNIKIIDFGFSICIPPGQKLNTFCGTPPYMAPEIFLKKPYDGPKVDIWSLGVVLYFMV VGKVPFDSFI--IPELQMQILAGVYPAPCGVSNELKDLLSLLMTVNPKYRPTVTEVMKHPWL .|..||| . ||. .||.|.|. || || |...|...|.||||..|||..|.|||||. CGYFPFDGDTQDYKELYKKILRGKYDIPCHVSKECRNLIQRLLTVNPEERPTIEEIMKHPWM |
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| Kinase | MarkmA11.AA | CAMKL | 28-276 | 40 | 4.2e-137 | 440.16 | In-house | 1-297 (297) | Show / Hide |
Range on Protein: 28-276 Range on HMM: 1-297/297 Sequence Identity: 40% (121 aa) YKVVRTLGHGTYAKVLLAQH-RLTGTPVAVKVLLKNKPCFQPAMK----------------EANIMKKIK---HPNIVSLLQVIETKTR------GYLIM |....|||.|...|| ||.| |.||. ||.|.. |.| . | || |..|||... ||||..|..||||.. ||.| YRIGKTLGKGSFGKVKLATHIRTTGEKVAIKIIDKKKIWNDPWMKKNKCGQKHESDMRIRREIQIMKMLNIGKHPNIIKLYEVIETPEHDIETKKIYLVM ELVEGQE--LYEYIKNSGH----IEEDEARQIFLQILSAVGYCHGSGIVHRDLKPDNIMIDSKGS--IKIIDFGLSTQVKP-----GQLLHEHCGAYAFG |...| | |..||.. || ..|.|||..| ||.||| ||| ||||||.||.||..|..|. |||||||.|.. .| ||.|...|| ... EYCSGGEMDLFDYIVKHGHRRGRMPEHEARRYFRQIVSAVNYCHSHGIVHRDIKPENILLDENGNNNIKIIDFGFSNMYRPCIFGPGQKLKTFCGSPPYM APELFLW--KSYDGTKSDLWALGVILYYMVVGKVPFDSFIIP---------ELQMQILAGVYPAPCGVSNELKDLLSLLMTVNPKYRPTVTEVMKHPWL |||.|. |.||| | | |..||||| ||.|..||| .. ... .. . .| .. || ...||.. ...|||..|||. ..|.|||. APEIFQGNNKPYDGPKVDIWSCGVILYAMVCGYLPFDDDTYNKQGKDNIYLYWKIMCG-YYPPIWYHVS-DCRDLIRKMLQVNPEKRPTIHQIMNHPWM |
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| Kinase | MarkmA11.AA | CAMK | 33-276 | 24 | 1.6e-117 | 380.44 | In-house | 1-425 (425) | Show / Hide |
Range on Protein: 33-276
Range on HMM: 1-425/425
Sequence Identity: 24% (106 aa)
TLGHGTYAKVLLAQHRLTG------------TPVAVKVLLKN-----------------------------KPCFQPAMKEANIMKK-------IKHPNI
|||.|...|| |..|..|. . ||.|.. |. . ..| .|||| ..||||
TLGRGSFGKVKLCIHKNTTGKERVHHIYTNGQKVAIKIIDKKKLKDKQNQDYSNCYKIDKSKCKHRYCWRRPKDRKNVRREIEIMKKLQGIGNKLDHPNI
VSLLQVIET-------------------KTRGYLIM---ELVEGQEL----YEYIKNSGH---------------IEEDEARQIFLQILSAVGYCHGSGI
..|..|.|. ... |..| |...| || ..||. |. ..|.|||..| ||.||| ||| .|
IKLYEVYEDPHYFKNTNDYETSKQVFTKDKHMYMVMEIMEYCSGGELFDDLFDYIVEHGCYGEEFDQFDIVERGRFTEREARRYFRQICSAVHYCHSHNI
VHRDLKPDNIMIDSK-----------------GSIKIIDFGLSTQVKP------------------------GQLLHEHCGAYAFGA-PELFLW------
|||||||.||..|.. . |||||||......| ||.... || .. | ||...
VHRDLKPENILLDDNNDDSDPVEHDEIFDWNNNNIKIIDFGFANKFDPGENNFMCSDYKGGEMHNQWTTPTEGQKMKTFCGTPEYMAAPEVLNGKGHCNM
-------KSYDGTKSDLWALGVILYYMVVGKVPFDSF-------------IIPELQMQILAGVYP-APCG---------------VSNE--------LKD
| |.| |.| |..||||| |..|. ||.. ..|| .|..| | | .|.| ||
QNATDEEKPYYGPKCDMWSCGVILYIMLCGYPPFYGDCDNEICEDEWIGMNDYELFEKIMKGKYDFPPPYFSPISCNYGPEWWDDISDEFHHFVSQECKD
LLSLLMTVNPKYRPTVTEVMKHPWL
|.. ...|.|. |.|......|||.
LIRKMLQVDPEKRMTIEQCLNHPWM
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| Kinase | MarkmA11.AA | AMPK | 28-276 | 42 | 3.6e-97 | 289.01 | In-house | 1-254 (254) | Show / Hide |
Range on Protein: 28-276 Range on HMM: 1-254/254 Sequence Identity: 42% (107 aa) YKVVRTLGHGTYAKVLLAQHRLTGTPVAVKVL----LKNKPCFQPAMKEANIMKKIKHPNIVSLLQVI-ETKTRGYLIMELVEGQELYEYIKNSGHIEED | . |.| ||. || .. | |||. ||.|.| .|.. . .| |.|...||.|. | .|| ||.| ...|| | | ||..|| | ..|. YIIGKTIGEGTFGKVKMGTHILTGEKVAIKILNKQKIKDQDMVERIQREIHILKLFRHPHIIQLYEVIIETPTDIFMVMEYVSGGELFDYIVKHGRLQER EARQIFLQILSAVGYCHGSGIVHRDLKPDNIMIDSKGSIKIIDFGLSTQVKPGQLLHEHCGAYAFGAPELFLWKSYDGTKSDLWALGVILYYMVVGKVPF ||. | ||.|.| ||| .|||||||| |. .| . .||| ||||| | |..| || |||. | | |.. |.| ||||| |. |. || EACRFFQQIISGVEYCHRHMIVHRDLKPENLLLDHNKNIKIVDFGLSNMMKDGEFLKTACGSPCYAAPEMISGKLYCGPEVDIWSCGVILYAMLCGYLPF DSFIIPELQMQILAGVYPAPCGVSNELKDLLSLLMTVNPKYRPTVTEVMKHPWL | .|.| |..|.|. | .|.| |||.. . .|.| | |. ....|||. DDENTPTLYKKIKNGEYYIPKFLSPEAKDLIKHMLQVDPMKRITIHDIRNHPWF |
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| Kinase | MarkmA11.AA | S_TKc | 28-276 | 33 | 5.1e-94 | 319.57 | SMART | 1-231 (231) | Show / Hide |
Range on Protein: 28-276 Range on HMM: 1-231/231 Sequence Identity: 33% (89 aa) YKVVRTLGHGTYAKVLLAQHRLTGTPVAVKVLLKNKPCFQPAMKEANIMKKIKHPNIVSLLQVIETKTRGYLIMELVEG--QELYEYIKNSGH------I |...|..|.|...|| ...|. || ||.|.. . ...| .|.|| .||||| |. |... .. |..||...| .|..|||. |. . YEILRKIGKGAFGKVYKCRHKKTGRIVAIKIIK------EHIRREIQILKK-HHPNIVKLYDVFQD-DHLYMVMEYCDGDLGDLFDYIKKRGRHGLRFPF EEDEARQIFLQILSAVGYCHGSGIVHRDLKPDNIMIDSKGSIKIIDFGLSTQVKPGQLLHEHCGAYAFGAPELFLWKSYDGTKSDLWALGVILYYMVVGK | .|| .. ||..|. ||| ||.||||||.||..|. |||.||||..|. . || . |||.. .|.. |.| |..|.||| |..|. PE-HARFYMYQICCALEYCHSHGIIHRDLKPENILLDE--HIKICDFGLARQL------TTFCGTPWYMAPEVL---GYGKCKCDWWSCGCILYEMLCGY VPFDSFIIPELQMQILAGVYPAPCGVSNELKDLLSLLMTVNPKYRPTVTEVMK-------HPWL ||. ... .... | |.||... .....|. |||. |... |||. PPFP---QMQMMFKKIG---------SPEAKDFIRKCLQKDPEKRPTA-EALQDEWDIKCHPWF |
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| Kinase | MarkmA11.AA | NuaK | 28-276 | 40 | 2e-92 | 243.24 | In-house | 1-252 (252) | Show / Hide |
Range on Protein: 28-276 Range on HMM: 1-252/252 Sequence Identity: 40% (102 aa) YKVVRTLGHGTYAKVLLAQHRLTGTPVAVKVLLKNKPCFQPAM----KEANIMKKIKHPNIVSLLQVIETKTRGYLIMELVEGQELYEYIKNSGHIEEDE |.. .||| ||| || || . || ||.| |.| . | .| || . ||.|.. | | | . ..|| | |||.|| . . . | | YEFQKTLGKGTYGKVKLATEHSTGREVAIKSIKKCKIEDEQDMVHIRREIEIMSSLNHPHIIHIYEVFENKDKIVIVMEYASGGELYDYISECKSLPERE ARQIFLQILSAVGYCHGSGIVHRDLKPDNIMIDSKGSIKIIDFGLSTQVKPGQLLHEHCGAYAFGAPELFLWKSYDGTKSDLWALGVILYYMVVGKVPFD ||..| || ||| ||| .|.||||| ||. | .. .|| ||||| . ...|| || . || . | | | |.|||.|| || | ||| ARHFFRQIVSAVHYCHKHRICHRDLKLENILLDQNCNAKIADFGLSNYYHDQKFLHTFCGSPLYASPEIVNGQPYHGPEVDCWSLGVLLYTMVYGTMPFD SFIIPELQMQILAGVYPAPCGVSNELKDLLSLLMTVNPKYRPTVTEVMKHPWL . .| || | | || | . | ...|||..| |. .. .|.|. GHDFKHLVKQISQGAYYEPCKPSDACM-LIRWMLMVNPRRRATIYDICHHWWV |
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| Kinase | MarkmA11.AA | QIK | 28-276 | 38 | 1.4e-87 | 297.31 | In-house | 1-272 (272) | Show / Hide |
Range on Protein: 28-276
Range on HMM: 1-272/272
Sequence Identity: 38% (104 aa)
YKVVRTLGHGTYAKVLLAQHRLTGTPVAVKVLLK---NKPCFQPAMKEANIMKKIKHPNIVSLLQVIETKTRGYLIMELVEGQELYEYIKNSGH------
| . ||.| | .| | ||.|| | | ||.|.. | .. .| | ||| ..||.|. |.||.||. |...| .. |...|. . |.
YDIERTIGKGNFAVVKLARHRITKTKVAIKIIDKSQLDEENLQKCYREVQIMKMLYHPHIIKLYQVMETDDMMYIVTEYCSNGEMFDYLCKHGRKGVKMV
--------------IEEDEARQIFLQILSAVGYCHGSGIVHRDLKPDNIMIDSKGSIKIIDFGLSTQVKPGQLLHEHCGAYAFGAPELFLWKSYDGTKSD
..|.|||..| ||.||| ||| .||||||| ||..|. |||.|||.| |.|||| || .. |||.|. |.||| |.|
NSPDIGDQVLMGVPMAENEARRWFWQICSAVHYCHKRNIVHRDLKAENILLDNNMNIKIADFGFSNWFKQGQLLMTWCGSPPYAAPEMFEGKEYDGPKVD
LWALGVILYYMVVGKVPFDSFIIPELQMQILAGVYPAPCGVSNELKDLLSLLMTVNPKYRPTVTEVMKHPWL
| .||.|| .| |. |||. ...|. .| | . | .| .. .| ..|.|. | |. ...|.|.
IWSMGVVLYVLVCGALPFDGKTLQNLRQRVLSGKFRIPFFMSQDCEHLIRHMLVVDPEHRYTIMQICQHRWM
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| Kinase | MarkmA11.AA | Pkinase | 28-276 | 32 | 1e-82 | 285.92 | Pfam | 1-293 (293) | Show / Hide |
Range on Protein: 28-276 Range on HMM: 1-293/293 Sequence Identity: 32% (97 aa) YKVVRTLGHGTYAKVLLAQHRLTGTPVAVKVLLKNKPCFQPAMK-----EANIMKKIKHPNIVSLLQVIETKTRGYLIMELVEGQ----ELYEYIK--NS |...|..| |....| ...|. || ||||.. | . . . |. |||...||||| |. . |.|.. |..||..|| .|..||. .. YHIGRKIGSGSFGCVYKCHHKGTGKIVAVKIIKKRHEKSWKDQTHRRLSEIQIMKRLNHPNIVRLYDWFEDKDHIYMVMEYCEGGLYVMDLFDYISTWRH GHI--EEDEARQIFLQILSAVGYCHGSGIVHRDLKPDNIMIDSKGSI----KIIDFGLSTQ--VKPGQLLHEHCGAYAFGAPELFLWKSYDGTKSDLWAL | . .|.|.. ...|||... ||| ||.||||||.||.||..| | ||.||||. | ... .. || . . |||. . .|.|.|.| |.. GCFYFSEWECKFYMYQILRGLEYCHSMGIIHRDLKPENILIDNNGHIDACVKICDFGLAKQFDY-NNS-MTTFCGTPWYMAPEVIRGGQYYGPKVDMWSC GVILYYMVVGKVPFDSF----------IIPELQMQILAGVYPAPCGVS-----------------NELKDLLSLLMTVNPKYRPTVTEVMKHPWL |.|||.|. |. ||.. .| . . .| .| .| .| |.||... . ...|| ||| .....|||. GCILYEMLCGRPPFPGHCWHDNHDQMQMICRIMGPPLHFDWPWWCSISYFFFRHWHFHWTFHNWSEECKDFIKWCLCKDPKKRPTAEQILQHPWF |
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| Kinase | MarkmA11.AA | Ciliate-E2 | 28-276 | 23 | 5.5e-75 | 255.42 | In-house | 1-365 (365) | Show / Hide |
Range on Protein: 28-276 Range on HMM: 1-365/365 Sequence Identity: 23% (89 aa) YKVVRTLGHGTYAKVLLAQHRLTGT-----------------------PVAVKVL----LKNKPCFQPAMKEAN----------IMKKIKHPNIVSLLQV ||... .| |....| ........ .|.|.. .... . |.| | |.....||||. . . YKFIKKIGQGNFGSVYKCKVWKVQKQFAIKIIDQKQQRQQMQEKVKIKIYAMKIMKKNQIEQIKQEIHIMREINCFYKKINEKNILEQLNHPNIIKMYEC IE--TKTRGYLIMELVEGQELYEYIKNS-----------GHIEEDEARQIFLQILS---------------AVGYCHGSG-IVHRDLKPDNIMIDSKGSI . ... ||.||...|..|..||||. . . | |...|. |||. |. |.| . |.|||.||.||.. | FQEKDDNNIYLVMEYCQGGDLFDYIKNNKKKRNHEIEKDKYFTEKEIKYIMKQILQGFKTKAEFYIACIILALEYLHSKNNIIHRDIKPENILF-----I KIIDFGLSTQVKP-----------GQLLHEH----------------------CGAYAFGAPELFLWKSYDG--------TKSDLWALGVILYYMVVGKV ||||||||..... . .. . || . . ||| . |.||. .|.|.|.||||||.|. || KIIDFGLSKKYDDDNQNRTHKQQCKWYMF-KNDTSRTPGYMDQIIQQNMFNTICGTPGYMAPEILNGKKYDNQQKQKGYDYKCDIWSLGVILYEMLFGKP PFDSFIIPELQMQILAGVYPAPCG------------------VSNELKDLLSL----LMTVNPKYRPT-VTEVMKHPWL || | ||. . . || .|.| |||.. .. ..|. |.| ....|||. PF--------QQQIKQCKIDFPCPEWQKDTQCIQCKWKSWKKWSQECKDLIKKFGKRMLQKDPEKRITGWEQILNHPWF |
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| Kinase | MarkmA11.AA | SNRK | 28-276 | 42 | 1e-74 | 244.0 | In-house | 1-254 (254) | Show / Hide |
Range on Protein: 28-276 Range on HMM: 1-254/254 Sequence Identity: 42% (108 aa) YKVVRTLGHGTYAKVLLAQHRLTGTPVAVKVLLKNK---PCFQPAMKEANIMKKIKHPNIVSLLQVIETKTRGYLIMELVEGQELYEYI-KNSGHIEEDE | . .|||.| .| | ||.| || |||||. | | ..| || ..||||| | ||.|.|. |||.|| .| ..|.|| | ..|| YDLEKTLGRGHFAVVKLARHVFTGEKVAVKVIDKTKMDEVSKAHLFQEVRCMKLVQHPNIVRLYEVIDTQTKLYLILELGDGYDMYDYIMKHEKGLCEDL ARQIFLQILSAVGYCHGSGIVHRDLKPDNIMIDSK-GSIKIIDFGLSTQVKPGQLLHEHCGAYAFGAPELFLWKSYDGTKSDLWALGVILYYMVVGKVPF ||. | ||. |. ||| .|||||||.|.. | | .|. ||| | . .||. |. ||. |. |||. | ||| |.|.|||||| .| |..|| ARKYFCQIMHAIDYCHQLHVVHRDLKPENVVFFEKQGMVKLTDFGFSNKFMPGEKLETSCGSLAYSAPEILLGDSYDAPAVDIWSLGVILYMLVCGQAPF DSFIIPELQMQILAGVYPAPCGVSNELKDLLSLLMTVNPKYRPTVTEVMKHPWL . | .|. | | ||.| .||. .. .|| | .. |. |.|. QEANDSETLTMIMDCKYTVPDHVSDECRDLIQSMLVRDPKKRASLEEIVSHSWV |
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| Kinase | MarkmA11.AA | Ciliate-E2-Unclassified | 28-276 | 25 | 8.5e-73 | 248.15 | In-house | 1-352 (352) | Show / Hide |
Range on Protein: 28-276
Range on HMM: 1-352/352
Sequence Identity: 25% (90 aa)
YKVVRTLGHGTYAKVLLAQHRLTGTPVAVKVLLKNKPCFQPAM-------KEANIMKKIK-------------------HPNIVSLLQVIETKTRGYLIM
||.....|.| ..|| ..||. .. | | . |.. . | . |...|...| ||.|| .. . ..| |..|
YKIIKQIGQGGFGKVYKCQHKKQKQYYAMKYMKKIQIYKQKQIMNKDEIMNEMKEMNNKKKYHQRKYNKIMQQILLNHPHPFIVKMFYCFQDKQNIYIVM
ELVEGQELYEYIKNSGH-----------------IEEDEAR-----QIFLQILSAVGYCHGSG-IVHRDLKPDNIMIDSKG---SIKIIDFGLSTQVK--
|..||..| .|||.... ..| .|. ..| |||.. |.| .. |.|||.||.||..|..| |||||||.| . .
EYCEGGDLWQYIKKRKKQKQKGNDLFHNMKQRKIFTEQQAKYKKAKFYFAQILQGLEYLHHKNNIIHRDIKPENILFDNNGKNYYIKIIDFGISKKYQQN
--------------PGQLLHEHCGAYAFG----APELFLWKSYDG---TKSDLWALGVILYYMVVGKVPFDSFIIPE----------------LQMQILA
. |... || . . |||.. . ||. |.| |.||||||.|. |. ||.. . |. .|..
NNCDTNQQQKMQIWKQQMMWTFCGTPNYMPQYTAPEVLQGQNYDHSKAYKCDIWSLGVILYEMLFGYYPFYDNNCEQHQQLITQWINNAYRKQLYQNIKQ
GVYP--------APCGVSNELKDLLS----LLMTVNPKYRPTVTEVMKHPWL
. . .|...|.| ||... .. .||..|.| ....|||.
KNIQFPKFPWQQIPKHWSPEAKDFINDLLQKMLKKNPNKRITFEQILNHPWF
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| Kinase | MarkmA11.AA | TSSK | 75-276 | 36 | 8.7e-66 | 214.89 | In-house | 68-289 (289) | Show / Hide |
Range on Protein: 75-276 Range on HMM: 68-289/289 Sequence Identity: 36% (81 aa) IMKK-IKHPNIVSLLQVIETKT-RGYLIMELVEGQELYEYIKNS------GHIEEDEARQIFLQILSAVGYCHGSGIVHRDLKPDNIMIDSKGSIKIIDF ||.| .|||||. ... .|| . |..||. |. | |||... | ..|..||. | |. ||| |||. ..|||||| || | . ||..|| IMRKTLKHPNIIQFYEMFETCQGKIYMVMEYAEHGDLLEYIQRRTQERCCGALHEEQARKWFRQMVSAVKYCHSHNVVHRDLKCENILLDKHWNIKLTDF GLSTQVKPGQ------LLHEHCGAYAFGAPELFLWKSYDGTKSDLWALGVILYYMVVGKVPFDS-----FIIPELQM-QILAGVYPA--PCGVSNELKDL | . ..... |. || || ||| .. . ||. ..| |..||||| ||.|. ||| ... |. . . .|. |..| | ||| GFARYWPRDDPGRCCHLSKTFCGSYAYAAPEILRGIPYDPKWYDVWSMGVILYIMVCGCMPFDDDKSNIHKMLWQQQEHKV--CFPKPHSCWISQECKDL LSLLMTVNPKYRPTVTEVMKHPWL .. ... .|. ||...|...|.|. IRHMLQPHPCNRPHINEICHHCWM |
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| Kinase | MarkmA11.AA | Pkinase_Tyr | 28-169 | 27 | 2.7e-21 | 72.72 | Pfam | 1-158 (270) | Show / Hide |
Range on Protein: 28-169 Range on HMM: 1-158/270 Sequence Identity: 27% (45 aa) YKVVRTLGHGTYAKVLLAQHR----LTGTPVAVKVLLKNKPCFQPA-------MKEANIMKKI-KHPNIVSLLQVIETKTRG---YLIMELVEGQELYEY . ..||.| . .| .. . |..|||||.| |. . |.||.|||.. .|||||.|. |. . . |..||.... |..| ITFGKKLGEGAFGEVYKGTWKGDPDNTKIPVAVKML-KE--GAMHEQNCREDFMREAKIMKQLGHHPNIVRLYGVCTDQGEPNQIYIVMEYMPHGDLLDY IKN----SGHIEEDEARQIFLQILSAVGYCHGSGIVHRDLKPDNIMIDSKGSIKIIDFGLS .. ... . |. .|| .. | . ...|||| |....... .|| ||||. LRKHREDKQPLTMKDLLQMCWQIAKGMEYLESKNCIHRDLAARNCLVTENNVVKICDFGLA |
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| Kinase | MarkmA11.AA | TyrKc | 28-276 | 22 | 1.1e-16 | 47.18 | SMART | 1-280 (280) | Show / Hide |
Range on Protein: 28-276 Range on HMM: 1-280/280 Sequence Identity: 22% (65 aa) YKVVRTLGHGTYAKVLLAQHRLTGTPVAVKVLLKNKPCFQPAMKEANIMKKI--KHPNIVSLLQVIETK-------TRGYLIMELVEGQELYEYIKNSGH . ..||.| . .| ... . ..||||.| ... . |.||.||.|. .||||| |. |. .. ...||.... | .|...... ITLGKKLGEGAFGEVYKGTWK---IQVAVKMLKEDA--REDFMREARIMCKLGGHHPNIVRLYGVCTQQGRNFMYIEPLMIVMEYMPHGDLKDYLRKHRP -IEEDEARQIFLQILSAVGYCHGSGIVHRDLKPDNIMIDSKGSIKIIDFGLSTQVKPG-------QLLHE----HC---GAYAFGAPELFLWKSYDGTKS . .. .. .|| . | | ...|||| |....... .|| ||||| .. . . . .. . ||| . . . ||| KLCMKDLLSFCWQIACGMEYLHSKNCIHRDLAARNCLVGENHTVKISDFGLSRDIYDDDQQGESKDYYRKKEHKGGKTMLPIRWMAPECINYGKFT-TKS DLWALGVILYYMV-VGKVPFDS-----FIIPELQMQILAG-VYPAPCG--------VSNELKDLLSLLMTVNPKYRPTVTEVMKHPWL | |. || .. . |. | |. .. .| | | . |. .. . .|. ||| .|. | . DVWSFGVCMWEIFTYGQQPYPGMIQQMMSNQEVIEYVKQGYRMPQPPNDYPMSFVCCPDEMYQIMKQCWHEDPEDRPTFSEI--HECF |
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| Kinase | MarkmA11.AA | TSSK | 28-58 | 27 | 1.6e-08 | 24.05 | In-house | 1-47 (289) | Show / Hide |
Range on Protein: 28-58 Range on HMM: 1-47/289 Sequence Identity: 27% (13 aa) YKVVRTLGHGTYAKVLLAQHRLTGTP----------------VAVKV |.| ...|||.|||| .|... . ||.|. YNVGKKIGHGSYAKVYCAYSKKHKCKHNPRLRDDLRIKRHTHVAIKI |
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| Kinase | MarkmA11.AA | APH | 142-170 | 27 | 0.000386 | 15.0 | Pfam | 171-203 (248) | Show / Hide |
Range on Protein: 142-170 Range on HMM: 171-203/248 Sequence Identity: 27% (9 aa) GIVHRDLKPDNIMID--SKGSIK--IIDFGLST ...|.|..|.|.|.| . | .||.. .. CWCHGDFHPGNVMWDPRPDGGRVTGVIDWDDAC |
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| UBA_CAMKL | MarkmA11.AA | UBA_CAMKL | 296-333 | 39 | 1.4e-13 | 46.82 | In-house | 1-41 (41) | Show / Hide |
Range on Protein: 296-333 Range on HMM: 1-41/41 Sequence Identity: 39% (16 aa) DPDIVDAMQYI--GFQAKDIRESLTKEKF-NEMSAAYYLLE |..|.. |. . ||. ..|.||| . |. |...|.|||| DEEIIQEMCKMWHGFDREEIIESLRNNKYHNHITATYYLLL |
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| UBA | MarkmA11.AA | UBA | 296-333 | 18 | 0.000269 | 21.52 | SMART | 1-38 (38) | Show / Hide |
Range on Protein: 296-333 Range on HMM: 1-38/38 Sequence Identity: 18% (7 aa) DPDIVDAMQYIGFQAKDIRESLTKEKFNEMSAAYYLLE . ..| . ||. ....| . . |. |...|.. YEEKIDQLMEMGFDREECVQALRACNWNVEMAMNWLFS |
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