MarkmA7

Species: Mouse
Alias: MarkmA7
External Links: Entrez Gene , Refseq cDNA , Refseq Protein , iHOP
Annotation:

Classification

Group: CAMK
Family: CAMKL
Subfamily: MARK

Sequence

Name Sequence Type Origin Length Description Download
MarkmA7.kin_dom Protein Kinase Domain Sugen global kinase HMM prediction 249 Kinase domain by global Sugen HMM Fasta, JSON
MarkmA7.NA RNA Sugen 2462 None Fasta, JSON
MarkmA7.AA Protein Sugen 504 None Fasta, JSON

Protein domain

Protein domains of MarkmA7.AA. The domains are annotated by HMM profiles from Pfam and SMART, as well as in-house data which includes HMMs of each individual kinase group, family and subfamily. Here is domain list in details, including sequence identity, significance and alignment. In particular, you can find can find the best hit kinase group/family/subfamily, which is helpful to understand the relationship between kinases.Kinase domain and best hit kinase group/family/subfamily are highlighted in red and blue. Visualized by pviz.

Usage: Zoom in selected region by dragging mouse and zoom out by double-clicking.

Domain Protein name Domain Name Range Identity (%) Significance Score Profile Source Profile Range (length) Alignment
Kinase MarkmA7.AA MARK 28-276 51 3.4e-168 553.68 In-house 1-262 (262) Show / Hide
Range on Protein: 28-276
Range on HMM: 1-262/262
Sequence Identity: 51% (135 aa)

YEMLGTIGHGGSTKVKLARHRLTGTHVAVKMIP---KRE-YWCKPLMSEAELLMMADHPNIISLLQVIE--TKKK-VYLIMELCEGKSLYQHIRNA--GY
|.|| |||||.  |||||.|..||..||.|...   . .  |.|..|.|.|.... ||||||.|..|||  |... .|||||...|..||..|...  |.
YKMLKTIGHGSYAKVKLACHKHTGRKVAIKIYEKFKLNDPQWMKNVMREIEIMKKLDHPNIIKLFHVIEQDTEQHQIYLIMEYASGGELYDYIKAHPNGR

LQEDEARALFKQLLSAINYCHNQGIVHRDLKPDNIMVEKDG--RVKIIDFGLGIQVKPGQKLNLFCGTYPFSAPEVLLSRPYDGPKIDVWTLGVVLYFMV
|.|.|||..|.|..||.||||...|||||.||.||.. ..|   .||||||..|...|||||| ||||.|. |||..|..||||||.|.|.|||||||||
LHEEEARRIFRQIVSAVNYCHSKNIVHRDIKPENILIDENGNHNIKIIDFGFSICIPPGQKLNTFCGTPPYMAPEIFLKKPYDGPKVDIWSLGVVLYFMV

TGKIPFDAAS--IEKLRKQIVAGKYSVPCRLSVKLHHLITLLMTDNPELRPTVAEVMMHPWV
.|. |||...  ...|.|.|..|||..||..|.....|| .|.| ||| |||. |.|.|||.
CGYFPFDGDTQDYKELYKKILRGKYDIPCHVSKECRNLIQRLLTVNPEERPTIEEIMKHPWM

Kinase MarkmA7.AA CAMKL 28-276 38 9.90000000001e-139 445.43 In-house 1-297 (297) Show / Hide
Range on Protein: 28-276
Range on HMM: 1-297/297
Sequence Identity: 38% (116 aa)

YEMLGTIGHGGSTKVKLARH-RLTGTHVAVKMIPKREYWCKPLMS----------------EAELLMMAD---HPNIISLLQVIETKKK------VYLIM
|... |.|.|.  |||||.| |.||..||.|.| |.  |..| |.                |.....| .   |||||.|..||||...      .||.|
YRIGKTLGKGSFGKVKLATHIRTTGEKVAIKIIDKKKIWNDPWMKKNKCGQKHESDMRIRREIQIMKMLNIGKHPNIIKLYEVIETPEHDIETKKIYLVM

ELCEGKS--LYQHIRNAGY----LQEDEARALFKQLLSAINYCHNQGIVHRDLKPDNIMVEKDG--RVKIIDFGLGIQVKP-----GQKLNLFCGTYPFS
|.|.| .  |...|.. |.    ..|.||| .|.|..||.||||..||||||.||.||.. ..|   .||||||.... .|     ||||. |||..|. 
EYCSGGEMDLFDYIVKHGHRRGRMPEHEARRYFRQIVSAVNYCHSHGIVHRDIKPENILLDENGNNNIKIIDFGFSNMYRPCIFGPGQKLKTFCGSPPYM

APEVLLS--RPYDGPKIDVWTLGVVLYFMVTGKIPFDAASI--------EKLRKQIVAGKYS-VPCRLSVKLHHLITLLMTDNPELRPTVAEVMMHPWV
|||....  .||||||.|.| .||.||.||.|. |||....        ....|...  .|  .....|  ...||  ... ||| |||. ..|.|||.
APEIFQGNNKPYDGPKVDIWSCGVILYAMVCGYLPFDDDTYNKQGKDNIYLYWKIMCG-YYPPIWYHVS-DCRDLIRKMLQVNPEKRPTIHQIMNHPWM

Kinase MarkmA7.AA CAMK 33-276 25 1.9e-121 393.31 In-house 1-425 (425) Show / Hide
Range on Protein: 33-276
Range on HMM: 1-425/425
Sequence Identity: 25% (107 aa)

TIGHGGSTKVKLARHRLTG------------THVAVKMIPKR-----------------------------EYWCKPLMSEAELLMM-------ADHPNI
|.|.|.  ||||..|..|.            ..||.|.|.|.                             ....| ...| |....        |||||
TLGRGSFGKVKLCIHKNTTGKERVHHIYTNGQKVAIKIIDKKKLKDKQNQDYSNCYKIDKSKCKHRYCWRRPKDRKNVRREIEIMKKLQGIGNKLDHPNI

ISLLQVIE------------TKKK--------VYLIM---ELCEGK----SLYQHIRNA---------------GYLQEDEARALFKQLLSAINYCHNQG
|.|..|.|            | .|        .|..|   |.|.|      |...|.                 |...|.||| .|.|..||..|||...
IKLYEVYEDPHYFKNTNDYET-SKQVFTKDKHMYMVMEIMEYCSGGELFDDLFDYIVEHGCYGEEFDQFDIVERGRFTEREARRYFRQICSAVHYCHSHN

IVHRDLKPDNIMVEKD-----------------GRVKIIDFGLGIQVKP------------------------GQKLNLFCGTYPFSA-PEVLLS-----
||||||||.||.. ..                 . .||||||. ....|                        |||.. |||| .. | ||||..     
IVHRDLKPENILLDDNNDDSDPVEHDEIFDWNNNNIKIIDFGFANKFDPGENNFMCSDYKGGEMHNQWTTPTEGQKMKTFCGTPEYMAAPEVLNGKGHCN

--------RPYDGPKIDVWTLGVVLYFMVTGKIPFDAA-------------SIEKLRKQIVAGKYS-VPCRLSV-----------------------KLH
        .||.|||.|.| .||.||.|..|. ||..              ....| ..| .|||.  |  .|                           
MQNATDEEKPYYGPKCDMWSCGVILYIMLCGYPPFYGDCDNEICEDEWIGMNDYELFEKIMKGKYDFPPPYFSPISCNYGPEWWDDISDEFHHFVSQECK

HLITLLMTDNPELRPTVAEVMMHPWV
.||  ... .|| |.|..... |||.
DLIRKMLQVDPEKRMTIEQCLNHPWM

Kinase MarkmA7.AA S_TKc 28-276 34 1.2e-94 321.65 SMART 1-231 (231) Show / Hide
Range on Protein: 28-276
Range on HMM: 1-231/231
Sequence Identity: 34% (90 aa)

YEMLGTIGHGGSTKVKLARHRLTGTHVAVKMIPKREYWCKPLMSEAELLMMADHPNIISLLQVIETKKKVYLIMELCEG--KSLYQHIRNAGY------L
||.| .||.|.  ||...||. || .||.|.|.      . ...| ..|.. .||||. |. |... ...|..||.|.|   .|...|.. |.      .
YEILRKIGKGAFGKVYKCRHKKTGRIVAIKIIK------EHIRREIQILKK-HHPNIVKLYDVFQD-DHLYMVMEYCDGDLGDLFDYIKKRGRHGLRFPF

QEDEARALFKQLLSAINYCHNQGIVHRDLKPDNIMVEKDGRVKIIDFGLGIQVKPGQKLNLFCGTYPFSAPEVLLSRPYDGPKIDVWTLGVVLYFMVTGK
 | .|| ...|...|..|||..||.||||||.||.. .  ..||.||||  |.      . ||||  . |||||   .|...|.|.| .|..|| |..|.
PE-HARFYMYQICCALEYCHSHGIIHRDLKPENILLDE--HIKICDFGLARQL------TTFCGTPWYMAPEVL---GYGKCKCDWWSCGCILYEMLCGY

IPFDAASIEKLRKQIVAGKYSVPCRLSVKLHHLITLLMTDNPELRPTVAEVMM-------HPWV
 ||.   .... |.|.          |  . ..|  ... .|| |||. |..        |||.
PPFP--QMQMMFKKIG----------SPEAKDFIRKCLQKDPEKRPTA-EALQDEWDIKCHPWF

Kinase MarkmA7.AA NuaK 28-276 39 3.3e-90 237.3 In-house 1-252 (252) Show / Hide
Range on Protein: 28-276
Range on HMM: 1-252/252
Sequence Identity: 39% (101 aa)

YEMLGTIGHGGSTKVKLARHRLTGTHVAVKMIPKREYWCKPLMS----EAELLMMADHPNIISLLQVIETKKKVYLIMELCEGKSLYQHIRNAGYLQEDE
||.. | | |   |||||. . ||  ||.| |.|     .  |     | |..   .||.||.   | | | |. ..||   |  ||  | . . | | |
YEFQKTLGKGTYGKVKLATEHSTGREVAIKSIKKCKIEDEQDMVHIRREIEIMSSLNHPHIIHIYEVFENKDKIVIVMEYASGGELYDYISECKSLPERE

ARALFKQLLSAINYCHNQGIVHRDLKPDNIMVEKDGRVKIIDFGLGIQVKPGQKLNLFCGTYPFSAPEVLLSRPYDGPKIDVWTLGVVLYFMVTGKIPFD
|| .| |  ||. |||  .|.|||||  ||.  ... .|| ||||    . .. |. |||   .  ||.   .|| || .| | |||.|| || |  |||
ARHFFRQIVSAVHYCHKHRICHRDLKLENILLDQNCNAKIADFGLSNYYHDQKFLHTFCGSPLYASPEIVNGQPYHGPEVDCWSLGVLLYTMVYGTMPFD

AASIEKLRKQIVAGKYSVPCRLSVKLHHLITLLMTDNPELRPTVAEVMMHPWV
     .| |||  |.|  ||. |.    ||  ... ||. | |. ..  |.||
GHDFKHLVKQISQGAYYEPCKPSDA-CMLIRWMLMVNPRRRATIYDICHHWWV

Kinase MarkmA7.AA AMPK 28-276 38 1.3e-87 260.19 In-house 1-254 (254) Show / Hide
Range on Protein: 28-276
Range on HMM: 1-254/254
Sequence Identity: 38% (97 aa)

YEMLGTIGHGGSTKVKLARHRLTGTHVAVKMIPKR----EYWCKPLMSEAELLMMADHPNIISLLQVI-ETKKKVYLIMELCEGKSLYQHIRNAGYLQED
| .  ||| | . |||.. | |||. ||.| . |.    .   . . .| ..| .  ||.|| | .|| ||..  ...||   |  |.  |   | |||.
YIIGKTIGEGTFGKVKMGTHILTGEKVAIKILNKQKIKDQDMVERIQREIHILKLFRHPHIIQLYEVIIETPTDIFMVMEYVSGGELFDYIVKHGRLQER

EARALFKQLLSAINYCHNQGIVHRDLKPDNIMVEKDGRVKIIDFGLGIQVKPGQKLNLFCGTYPFSAPEVLLSRPYDGPKIDVWTLGVVLYFMVTGKIPF
||. .|.| .|.. |||. .|||||||| |.   .. ..|| ||||    | |..|   ||     |||.  ...| ||..|.|  ||.|| |. |. ||
EACRFFQQIISGVEYCHRHMIVHRDLKPENLLLDHNKNIKIVDFGLSNMMKDGEFLKTACGSPCYAAPEMISGKLYCGPEVDIWSCGVILYAMLCGYLPF

DAASIEKLRKQIVAGKYSVPCRLSVKLHHLITLLMTDNPELRPTVAEVMMHPWV
|  .. .| | |..|.|..|  || . . ||  . . .|. | |. ... ||| 
DDENTPTLYKKIKNGEYYIPKFLSPEAKDLIKHMLQVDPMKRITIHDIRNHPWF

Kinase MarkmA7.AA QIK 28-276 37 3.6e-87 295.9 In-house 1-272 (272) Show / Hide
Range on Protein: 28-276
Range on HMM: 1-272/272
Sequence Identity: 37% (103 aa)

YEMLGTIGHGGSTKVKLARHRLTGTHVAVKMIPK----REYWCKPLMSEAELLMMADHPNIISLLQVIETKKKVYLIMELCEGKSLYQHIRNAGY-----
|..  ||| |    ||||||| | | ||.| | |    .|.  | .  | ... | .||.|| |.||.||..  |...| |..  .. .. . |      
YDIERTIGKGNFAVVKLARHRITKTKVAIKIIDKSQLDEENLQK-CYREVQIMKMLYHPHIIKLYQVMETDDMMYIVTEYCSNGEMFDYLCKHGRKGVKM

---------------LQEDEARALFKQLLSAINYCHNQGIVHRDLKPDNIMVEKDGRVKIIDFGLGIQVKPGQKLNLFCGTYPFSAPEVLLSRPYDGPKI
               ..|.|||  |.|..||. |||...|||||||  ||.  ..  .||.|||..   |.|| |. .||. |. |||... . |||||.
VNSPDIGDQVLMGVPMAENEARRWFWQICSAVHYCHKRNIVHRDLKAENILLDNNMNIKIADFGFSNWFKQGQLLMTWCGSPPYAAPEMFEGKEYDGPKV

DVWTLGVVLYFMVTGKIPFDAASIEKLRKQIVAGKYSVPCRLSVKLHHLITLLMTDNPELRPTVAEVMMHPWV
|.| .||||| .|.|..|||  ....||. .. ||. .|  .|. . |||   .. .|| | |.. .. |.| 
DIWSMGVVLYVLVCGALPFDGKTLQNLRQRVLSGKFRIPFFMSQDCEHLIRHMLVVDPEHRYTIMQICQHRWM

Kinase MarkmA7.AA Pkinase 28-276 29 3.1e-85 294.27 Pfam 1-293 (293) Show / Hide
Range on Protein: 28-276
Range on HMM: 1-293/293
Sequence Identity: 29% (87 aa)

YEMLGTIGHGGSTKVKLARHRLTGTHVAVKMIPKREYWCKPLMS-----EAELLMMADHPNIISLLQVIETKKKVYLIMELCEGK----SLYQHIR--NA
|. ...|| |.. .|....|. ||  |||| |.||.  .. ...     |.... . .||||. |. . |.|...|..||.|||     .|. .|.  . 
YHIGRKIGSGSFGCVYKCHHKGTGKIVAVKIIKKRHEKSWKDQTHRRLSEIQIMKRLNHPNIVRLYDWFEDKDHIYMVMEYCEGGLYVMDLFDYISTWRH

GYL--QEDEARALFKQLLSAINYCHNQGIVHRDLKPDNIMVEKDGRV----KIIDFGLGIQ--VKPGQKLNLFCGTYPFSAPEVLLSRPYDGPKIDVWTL
| .  .|.|..  ..|.|....|||..||.||||||.||.. ..| .    ||.||||  |    ... .. ||||... ||||.....|.|||.|.| .
GCFYFSEWECKFYMYQILRGLEYCHSMGIIHRDLKPENILIDNNGHIDACVKICDFGLAKQFDY-NNS-MTTFCGTPWYMAPEVIRGGQYYGPKVDMWSC

GVVLYFMVTGKIPFDAA------SIEKLRKQIVAGKYSVPCRLS---------------------VKLHHLITLLMTDNPELRPTVAEVMMHPWV
|..|| |..|. ||. .      .  .. ..|  .... ..  .                       . ..|. . . .|. ||| .... |||.
GCILYEMLCGRPPFPGHCWHDNHDQMQMICRIMGPPLHFDWPWWCSISYFFFRHWHFHWTFHNWSEECKDFIKWCLCKDPKKRPTAEQILQHPWF

Kinase MarkmA7.AA SNRK 28-276 42 8.1e-78 254.35 In-house 1-254 (254) Show / Hide
Range on Protein: 28-276
Range on HMM: 1-254/254
Sequence Identity: 42% (107 aa)

YEMLGTIGHGGSTKVKLARHRLTGTHVAVKMIPKR---EYWCKPLMSEAELLMMADHPNIISLLQVIETKKKVYLIMELCEGKSLYQHI-RNAGYLQEDE
|..  |.|.|    ||||||  || .||||.| |    |     |. |   . .  ||||. |  ||.|. |.|||.|| .|  .| .| .    |.|| 
YDLEKTLGRGHFAVVKLARHVFTGEKVAVKVIDKTKMDEVSKAHLFQEVRCMKLVQHPNIVRLYEVIDTQTKLYLILELGDGYDMYDYIMKHEKGLCEDL

ARALFKQLLSAINYCHNQGIVHRDLKPDN-IMVEKDGRVKIIDFGLGIQVKPGQKLNLFCGTYPFSAPEVLLSRPYDGPKIDVWTLGVVLYFMVTGKIPF
||  |.|.. ||.|||   .|||||||.| .  || | ||. |||   . .||.||. .||   .||||.||   || | .|.| |||.|| .| |. ||
ARKYFCQIMHAIDYCHQLHVVHRDLKPENVVFFEKQGMVKLTDFGFSNKFMPGEKLETSCGSLAYSAPEILLGDSYDAPAVDIWSLGVILYMLVCGQAPF

DAASIEKLRKQIVAGKYSVPCRLSVKLHHLITLLMTDNPELRPTVAEVMMHPWV
. |       .|.  ||.|| ..| . . ||. ..  .|. | .. |.  |.||
QEANDSETLTMIMDCKYTVPDHVSDECRDLIQSMLVRDPKKRASLEEIVSHSWV

Kinase MarkmA7.AA TSSK 28-276 32 5.1e-73 238.99 In-house 1-289 (289) Show / Hide
Range on Protein: 28-276
Range on HMM: 1-289/289
Sequence Identity: 32% (94 aa)

YEMLGTIGHGGSTKVKLARHRLTGTH----------------VAVKMIPK----REYWCKPLMSEAELLMM-ADHPNIISLLQVIETKK-KVYLIMELCE
|..  .||||   ||..|... .  .                ||.| | .    ..|  | |  | . . .  .||||| ... .||   |.|..||..|
YNVGKKIGHGSYAKVYCAYSKKHKCKHNPRLRDDLRIKRHTHVAIKIIDRKKAPTDYLNKFLPREIQIMRKTLKHPNIIQFYEMFETCQGKIYMVMEYAE

GKSLYQHIRNA------GYLQEDEARALFKQLLSAINYCHNQGIVHRDLKPDNIMVEKDGRVKIIDFGLGIQVKPGQ------KLNLFCGTYPFSAPEVL
.  | ..|..       | |.|..||..|.|. ||. |||. ..||||||  ||   |....|..||| .  .....      ..  ||| |  .|||.|
HGDLLEYIQRRTQERCCGALHEEQARKWFRQMVSAVKYCHSHNVVHRDLKCENILLDKHWNIKLTDFGFARYWPRDDPGRCCHLSKTFCGSYAYAAPEIL

LSRPYDGPKIDVWTLGVVLYFMVTGKIPFDA--ASIEKLRKQIVAGKYSVP----CRLSVKLHHLITLLMTDNPELRPTVAEVMMHPWV
...|||. . ||| .||.|| ||.|. |||     | |. .|. . | . |    | .|    .||  ... .| .||.. |.. |.|.
RGIPYDPKWYDVWSMGVILYIMVCGCMPFDDDKSNIHKMLWQQQEHKVCFPKPHSCWISQECKDLIRHMLQPHPCNRPHINEICHHCWM

Kinase MarkmA7.AA Ciliate-E2 28-276 22 5.4e-73 248.82 In-house 1-365 (365) Show / Hide
Range on Protein: 28-276
Range on HMM: 1-365/365
Sequence Identity: 22% (86 aa)

YEMLGTIGHGGSTKVKLARHRLTGTH-----------------------VAVKMIPKREYWCKP----LMSEAE----------LLMMADHPNIISLLQV
|. .  || |.  .|.........                         .|.|.. |..   .     .| | .          .|   .||||| .  .
YKFIKKIGQGNFGSVYKCKVWKVQKQFAIKIIDQKQQRQQMQEKVKIKIYAMKIMKKNQIEQIKQEIHIMREINCFYKKINEKNILEQLNHPNIIKMYEC

IE--TKKKVYLIMELCEGKSLYQHIRNA-----------GYLQEDEARALFKQLLS---------------AINYCHNQG-IVHRDLKPDNIMVEKDGRV
 .  .....||.||.|.|..|...|.|            .|. | |.. ..||.|.               |..|.|... |.|||.||.||..     .
FQEKDDNNIYLVMEYCQGGDLFDYIKNNKKKRNHEIEKDKYFTEKEIKYIMKQILQGFKTKAEFYIACIILALEYLHSKNNIIHRDIKPENILF-----I

KIIDFGLGIQVKPGQKLNL--------------------------------FCGTYPFSAPEVLLSRPYDG--------PKIDVWTLGVVLYFMVTGKIP
|||||||  .... .. ..                                .|||... |||.| . .||.         |.|.| |||.||.|..|| |
KIIDFGLSKKYDDDNQNRTHKQQCKWYMFKNDTSRTPGYMDQIIQQNMFNTICGTPGYMAPEILNGKKYDNQQKQKGYDYKCDIWSLGVILYEMLFGKPP

FDAASIEKLRKQIVAGKYSVPCR------------------LSVKLHHLITL----LMTDNPELRPT-VAEVMMHPWV
|         .||  .|.. ||                   .| .  .||      ..  .|| |.|   ... ||| 
F--------QQQIKQCKIDFPCPEWQKDTQCIQCKWKSWKKWSQECKDLIKKFGKRMLQKDPEKRITGWEQILNHPWF

Kinase MarkmA7.AA Ciliate-E2-Unclassified 28-276 23 4.3e-70 239.18 In-house 1-352 (352) Show / Hide
Range on Protein: 28-276
Range on HMM: 1-352/352
Sequence Identity: 23% (83 aa)

YEMLGTIGHGGSTKVKLARHRLTGTHV-------AVKMIPKREY------------WCK----------PLMSEAELLMMADHPNIISLLQVIETKKKVY
|... .||.||  ||....|. ..  .        .... .. .            ...           .| .  .| . .||.|. .. . ..|...|
YKIIKQIGQGGFGKVYKCQHKKQK-QYYAMKYMKKIQIYKQKQIMNKDEIMNEMKEMNNKKKYHQRKYNKIMQQ--ILLNHPHPFIVKMFYCFQDKQNIY

LIMELCEGKSLYQHIRN-----------------AGYLQEDEAR-----ALFKQLLSAINYCHNQG-IVHRDLKPDNIMVEKDG---RVKIIDFGL--GI
..||.|||..| |.|..                    ..| .|.      .|.|.|....|.| .. |.|||.||.||.. ..|   ..||||||.   .
IVMEYCEGGDLWQYIKKRKKQKQKGNDLFHNMKQRKIFTEQQAKYKKAKFYFAQILQGLEYLHHKNNIIHRDIKPENILFDNNGKNYYIKIIDFGISKKY

QVKPG--------------QKLNLFCGTYPFS----APEVLLSRPYDGP---KIDVWTLGVVLYFMVTGKIPFDAASIEK----------------LRKQ
|  ..              |... ||||. .     ||||| .  ||..   |.|.|.|||.||.|..|. ||.. . |.                |...
QQNNNCDTNQQQKMQIWKQQMMWTFCGTPNYMPQYTAPEVLQGQNYDHSKAYKCDIWSLGVILYEMLFGYYPFYDNNCEQHQQLITQWINNAYRKQLYQN

IVAGKYSVPC--------RLSVKLHHLIT----LLMTDNPELRPTVAEVMMHPWV
| ......|.        ..| .  ..|.     ..  ||. |.|  ... ||| 
IKQKNIQFPKFPWQQIPKHWSPEAKDFINDLLQKMLKKNPNKRITFEQILNHPWF

Kinase MarkmA7.AA Pkinase_Tyr 28-168 25 5.6e-17 58.12 Pfam 1-157 (270) Show / Hide
Range on Protein: 28-168
Range on HMM: 1-157/270
Sequence Identity: 25% (40 aa)

YEMLGTIGHGGSTKVKLARHR----LTGTHVAVKMIPKREYWCKP-----LMSEAELLMMA-DHPNIISLLQVIE-TKKK--VYLIMELCEGKSLYQHIR
 ... ..|.|   .|.... .     |...|||||. |  .  .      .|.||....   .||||..|. |.   ..   .|..||.... .|. . |
ITFGKKLGEGAFGEVYKGTWKGDPDNTKIPVAVKML-KEGAMHEQNCREDFMREAKIMKQLGHHPNIVRLYGVCTDQGEPNQIYIVMEYMPHGDLLDYLR

N----AGYLQEDEARALFKQLLSAINYCHNQGIVHRDLKPDNIMVEKDGRVKIIDFGL
.     . |   .      |  .. .| ......||||   |..|.... ||| ||||
KHREDKQPLTMKDLLQMCWQIAKGMEYLESKNCIHRDLAARNCLVTENNVVKICDFGL

Kinase MarkmA7.AA TyrKc 28-276 21 3.9e-16 38.24 SMART 1-280 (280) Show / Hide
Range on Protein: 28-276
Range on HMM: 1-280/280
Sequence Identity: 21% (61 aa)

YEMLGTIGHGGSTKVKLARHRLTGTHVAVKMIPKREYWCKPLMSEAELLMMA--DHPNIISLLQVIETK-------KKVYLIMELCEGKSLYQHIRNAGY
 ... ..|.|   .| ... .   . |||||. .     . .|.||.....   .||||. |. |. ..       . ....||.... .| ...|. . 
ITLGKKLGEGAFGEVYKGTWK---IQVAVKMLKEDA--REDFMREARIMCKLGGHHPNIVRLYGVCTQQGRNFMYIEPLMIVMEYMPHGDLKDYLRKHRP

-LQEDEARALFKQLLSAINYCHNQGIVHRDLKPDNIMVEKDGRVKIIDFGLGIQVKPG------QKLNLF----CGT--YPF--SAPEVLLSRPYDGPKI
 |. ..      |  .  .| | ....||||   |..| ....||| ||||   .. .      ..        .|    |    |||..  . .  .| 
KLCMKDLLSFCWQIACGMEYLHSKNCIHRDLAARNCLVGENHTVKISDFGLSRDIYDDDQQGESKDYYRKKEHKGGKTMLPIRWMAPECINYGKFT-TKS

DVWTLGVVLYFMVT-GKIPFDA-----ASIEKLRKQIVAGKYSVPCRL---------SVKLHHLITLLMTDNPELRPTVAEVMMHPWV
|||  ||... . | |. |         | . ..... .|..  .            . ... ...     .|| ||| .|.  |   
DVWSFGVCMWEIFTYGQQPYPGMIQQMMSNQEVIEYVKQGYRMPQPPNDYPMSFVCCPDEMYQIMKQCWHEDPEDRPTFSEI--HECF

Kinase MarkmA7.AA APH 119-167 22 0.000505 14.6 Pfam 151-200 (248) Show / Hide
Range on Protein: 119-167
Range on HMM: 151-200/248
Sequence Identity: 22% (12 aa)

LQEDEARALFKQLLSAINYCHNQGIVHRDLKPDNIMVE--KDGRVK--IIDFG
.|.. .. |. .|...       ...|.|..|.|.|.    ||     .||..
RQWWLWQRLWAWLEAHWP---PPCWCHGDFHPGNVMWDPRPDGGRVTGVIDWD

UBA_CAMKL MarkmA7.AA UBA_CAMKL 296-333 36 5.8e-13 44.64 In-house 1-41 (41) Show / Hide
Range on Protein: 296-333
Range on HMM: 1-41/41
Sequence Identity: 36% (15 aa)

DPAIVKAMGHI--GFQAQDIEDSLRQRKF-NETMASYCLLK
|. |.. | ..  ||. ..|..|||..|. |. .| |.|| 
DEEIIQEMCKMWHGFDREEIIESLRNNKYHNHITATYYLLL