Gene MarkmA8 (Mouse)
MarkmA8
Sequence
| Name | Sequence Type | Origin | Length | Description | Download |
|---|---|---|---|---|---|
| MarkmA8.NA | RNA | Sugen | 2318 | None | Fasta, JSON |
| MarkmA8.kin_dom | Protein Kinase Domain | Sugen global kinase HMM prediction | 249 | Kinase domain by global Sugen HMM | Fasta, JSON |
| MarkmA8.AA | Protein | Sugen | 433 | None | Fasta, JSON |
Protein domains of MarkmA8.AA. The domains are annotated by HMM profiles from Pfam and SMART, as well as in-house data which includes HMMs of each individual kinase group, family and subfamily. Here is domain list in details, including sequence identity, significance and alignment. In particular, you can find can find the best hit kinase group/family/subfamily, which is helpful to understand the relationship between kinases.Kinase domain and best hit kinase group/family/subfamily are highlighted in red and blue. Visualized by pviz.
Usage: Zoom in selected region by dragging mouse and zoom out by double-clicking.
| Domain | Protein name | Domain Name | Range | Identity (%) | Significance | Score | Profile Source | Profile Range (length) | Alignment |
|---|---|---|---|---|---|---|---|---|---|
| Kinase | MarkmA8.AA | MARK | 8-256 | 47 | 4.90000000001e-156 | 513.38 | In-house | 1-262 (262) | Show / Hide |
Range on Protein: 8-256 Range on HMM: 1-262/262 Sequence Identity: 47% (125 aa) YEMLETIGQGGCAQVKLAQHRLTGTHVAVKVIV---KRE-CWFNPVMSEAELLMMTDHPNIISLLQVIE--TKKK-LYLIMELCEGKSLYQHIQNA--GY |.|| |||.|..|.||||.|..||..||.|.. . . .|...||.|.|.... ||||||.|..||| |... .|||||...|..||..|... |. YKMLKTIGHGSYAKVKLACHKHTGRKVAIKIYEKFKLNDPQWMKNVMREIEIMKKLDHPNIIKLFHVIEQDTEQHQIYLIMEYASGGELYDYIKAHPNGR LQEDEACPLFKQLLSAVNYCHNQGIVHRDLTPDNIMVEKDG--KVKIIDFGLGTQEKPAQKLNLFCENYPFSTPEVLLSRPYDMRKIDVWGLGVVLYFMV |.|.|| .|.|..|||||||...|||||. |.||.. ..| ..||||||.... .| |||| || .|. ||..|..||| .|.|.| ||||||||| LHEEEARRIFRQIVSAVNYCHSKNIVHRDIKPENILIDENGNHNIKIIDFGFSICIPPGQKLNTFCGTPPYMAPEIFLKKPYDGPKVDIWSLGVVLYFMV TGKILFDAAS--IEKLRKQIVAGKCSVPCRLSVELQDLIRLLMTDNPELRPTVAEVMVHPWV .|. ||... ...|.|.|..||...||..|.|...||..|.| ||| |||. |.| |||. CGYFPFDGDTQDYKELYKKILRGKYDIPCHVSKECRNLIQRLLTVNPEERPTIEEIMKHPWM |
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| Kinase | MarkmA8.AA | CAMKL | 8-256 | 36 | 1.2e-127 | 409.44 | In-house | 1-297 (297) | Show / Hide |
Range on Protein: 8-256 Range on HMM: 1-297/297 Sequence Identity: 36% (109 aa) YEMLETIGQGGCAQVKLAQH-RLTGTHVAVKVIVKRECWFNPVMS----------------EAELLMMTD---HPNIISLLQVIETKKK------LYLIM |....|.|.|....||||.| |.||..||.|.| |. .| .|.|. |.....| . |||||.|..||||... .||.| YRIGKTLGKGSFGKVKLATHIRTTGEKVAIKIIDKKKIWNDPWMKKNKCGQKHESDMRIRREIQIMKMLNIGKHPNIIKLYEVIETPEHDIETKKIYLVM ELCEGKS--LYQHIQNAGY----LQEDEACPLFKQLLSAVNYCHNQGIVHRDLTPDNIMVEKDG--KVKIIDFGLGTQEKP-----AQKLNLFCENYPFS |.|.| . |...|.. |. ..|.||. .|.|..|||||||..||||||. |.||.. ..| ..||||||.... .| |||. || .|. EYCSGGEMDLFDYIVKHGHRRGRMPEHEARRYFRQIVSAVNYCHSHGIVHRDIKPENILLDENGNNNIKIIDFGFSNMYRPCIFGPGQKLKTFCGSPPYM TPEVLLS--RPYDMRKIDVWGLGVVLYFMVTGKILFDAASI--------EKLRKQIVAGKCS-VPCRLSVELQDLIRLLMTDNPELRPTVAEVMVHPWV ||.... .||| .|.|.| .||.||.||.|. ||.... ....|... .. .....| ...|||| ... ||| |||. ..| |||. APEIFQGNNKPYDGPKVDIWSCGVILYAMVCGYLPFDDDTYNKQGKDNIYLYWKIMCG-YYPPIWYHVS-DCRDLIRKMLQVNPEKRPTIHQIMNHPWM |
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| Kinase | MarkmA8.AA | CAMK | 13-256 | 23 | 4.8e-108 | 349.32 | In-house | 1-425 (425) | Show / Hide |
Range on Protein: 13-256
Range on HMM: 1-425/425
Sequence Identity: 23% (100 aa)
TIGQGGCAQVKLAQHRLTG------------THVAVKVIVKR-----------------------------ECWFNPVMSEAELLMM-------TDHPNI
|.|.|. ..|||..|..|. ..||.|.| |. ... |..| |.... |||||
TLGRGSFGKVKLCIHKNTTGKERVHHIYTNGQKVAIKIIDKKKLKDKQNQDYSNCYKIDKSKCKHRYCWRRPKDRKNVRREIEIMKKLQGIGNKLDHPNI
ISLLQVIE------------TKKK--------LYLIM---ELCEGK----SLYQHIQNA---------------GYLQEDEACPLFKQLLSAVNYCHNQG
|.|..|.| | .| .|..| |.|.| |...|. |...|.||. .|.|..|||.|||...
IKLYEVYEDPHYFKNTNDYET-SKQVFTKDKHMYMVMEIMEYCSGGELFDDLFDYIVEHGCYGEEFDQFDIVERGRFTEREARRYFRQICSAVHYCHSHN
IVHRDLTPDNIMVEKD-----------------GKVKIIDFGLGTQEKP------------------------AQKLNLFCENYPFST-PEVLLS-----
|||||| |.||.. .. ...||||||. .. .| ||.. || .. ||||..
IVHRDLKPENILLDDNNDDSDPVEHDEIFDWNNNNIKIIDFGFANKFDPGENNFMCSDYKGGEMHNQWTTPTEGQKMKTFCGTPEYMAAPEVLNGKGHCN
--------RPYDMRKIDVWGLGVVLYFMVTGKILFDAA-------------SIEKLRKQIVAGKCS-VPCRLSV-----------------------ELQ
.||. .|.|.| .||.||.|..|. |.. ....| ..| .||.. | .| | .
MQNATDEEKPYYGPKCDMWSCGVILYIMLCGYPPFYGDCDNEICEDEWIGMNDYELFEKIMKGKYDFPPPYFSPISCNYGPEWWDDISDEFHHFVSQECK
DLIRLLMTDNPELRPTVAEVMVHPWV
|||| ... .|| |.|..... |||.
DLIRKMLQVDPEKRMTIEQCLNHPWM
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| Kinase | MarkmA8.AA | S_TKc | 8-256 | 32 | 1.3e-85 | 291.66 | SMART | 1-231 (231) | Show / Hide |
Range on Protein: 8-256 Range on HMM: 1-231/231 Sequence Identity: 32% (86 aa) YEMLETIGQGGCAQVKLAQHRLTGTHVAVKVIVKRECWFNPVMSEAELLMMTDHPNIISLLQVIETKKKLYLIMELCEG--KSLYQHIQNAGY------L ||.|..||.|. ..|....|. || .||.|.| . ...| ..|.. .||||. |. |... ..||..||.|.| .|...|.. |. . YEILRKIGKGAFGKVYKCRHKKTGRIVAIKIIK------EHIRREIQILKK-HHPNIVKLYDVFQD-DHLYMVMEYCDGDLGDLFDYIKKRGRHGLRFPF QEDEACPLFKQLLSAVNYCHNQGIVHRDLTPDNIMVEKDGKVKIIDFGLGTQEKPAQKLNLFCENYPFSTPEVLLSRPYDMRKIDVWGLGVVLYFMVTGK | .|. ...|...|..|||..||.|||| |.||.. . .||.|||| .| . || . |||| .|. .|.|.| .|..|| |..|. PE-HARFYMYQICCALEYCHSHGIIHRDLKPENILLDE--HIKICDFGLARQL------TTFCGTPWYMAPEVL---GYGKCKCDWWSCGCILYEMLCGY ILFDAASIEKLRKQIVAGKCSVPCRLSVELQDLIRLLMTDNPELRPTVAEVMV-------HPWV .|. .... |.|. | |. |.|| ... .|| |||. |.. |||. PPFP--QMQMMFKKIG----------SPEAKDFIRKCLQKDPEKRPTA-EALQDEWDIKCHPWF |
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| Kinase | MarkmA8.AA | QIK | 8-256 | 34 | 7.1e-78 | 265.02 | In-house | 1-272 (272) | Show / Hide |
Range on Protein: 8-256
Range on HMM: 1-272/272
Sequence Identity: 34% (95 aa)
YEMLETIGQGGCAQVKLAQHRLTGTHVAVKVIVKR---ECWFNPVMSEAELLMMTDHPNIISLLQVIETKKKLYLIMELCEGKSLYQHIQNAGY------
|.. ||| | | ||||.|| | | ||.|.| | | .. . | ... | .||.|| |.||.||.. .|...| |.. .. .. . |
YDIERTIGKGNFAVVKLARHRITKTKVAIKIIDKSQLDEENLQKCYREVQIMKMLYHPHIIKLYQVMETDDMMYIVTEYCSNGEMFDYLCKHGRKGVKMV
--------------LQEDEACPLFKQLLSAVNYCHNQGIVHRDLTPDNIMVEKDGKVKIIDFGLGTQEKPAQKLNLFCENYPFSTPEVLLSRPYDMRKID
..|.|| |.|..||| |||...|||||| ||. .. .||.|||.. |. | |. .| |. ||... . || |.|
NSPDIGDQVLMGVPMAENEARRWFWQICSAVHYCHKRNIVHRDLKAENILLDNNMNIKIADFGFSNWFKQGQLLMTWCGSPPYAAPEMFEGKEYDGPKVD
VWGLGVVLYFMVTGKILFDAASIEKLRKQIVAGKCSVPCRLSVELQDLIRLLMTDNPELRPTVAEVMVHPWV
.| .||||| .|.|.. || ....||. .. || .| .|.....||| .. .|| | |.. .. |.|
IWSMGVVLYVLVCGALPFDGKTLQNLRQRVLSGKFRIPFFMSQDCEHLIRHMLVVDPEHRYTIMQICQHRWM
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| Kinase | MarkmA8.AA | AMPK | 8-256 | 36 | 1.8e-75 | 223.51 | In-house | 1-254 (254) | Show / Hide |
Range on Protein: 8-256 Range on HMM: 1-254/254 Sequence Identity: 36% (92 aa) YEMLETIGQGGCAQVKLAQHRLTGTHVAVKVI----VKRECWFNPVMSEAELLMMTDHPNIISLLQVI-ETKKKLYLIMELCEGKSLYQHIQNAGYLQED | . .||| | ||.. | |||. ||.|.. | . . . .| ..| . ||.|| | .|| ||.. ....|| | |. | | |||. YIIGKTIGEGTFGKVKMGTHILTGEKVAIKILNKQKIKDQDMVERIQREIHILKLFRHPHIIQLYEVIIETPTDIFMVMEYVSGGELFDYIVKHGRLQER EACPLFKQLLSAVNYCHNQGIVHRDLTPDNIMVEKDGKVKIIDFGLGTQEKPAQKLNLFCENYPFSTPEVLLSRPYDMRKIDVWGLGVVLYFMVTGKILF ||| .|.| .|.| |||. .|||||| | |. .. ..|| |||| | ...| | ||. ...| ...|.| ||.|| |. |. | EACRFFQQIISGVEYCHRHMIVHRDLKPENLLLDHNKNIKIVDFGLSNMMKDGEFLKTACGSPCYAAPEMISGKLYCGPEVDIWSCGVILYAMLCGYLPF DAASIEKLRKQIVAGKCSVPCRLSVELQDLIRLLMTDNPELRPTVAEVMVHPWV | .. .| | |..|. ..| || | .|||. . . .|. | |. ... ||| DDENTPTLYKKIKNGEYYIPKFLSPEAKDLIKHMLQVDPMKRITIHDIRNHPWF |
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| Kinase | MarkmA8.AA | Pkinase | 8-256 | 27 | 5.1e-72 | 250.36 | Pfam | 1-293 (293) | Show / Hide |
Range on Protein: 8-256 Range on HMM: 1-293/293 Sequence Identity: 27% (83 aa) YEMLETIGQGGCAQVKLAQHRLTGTHVAVKVIVKRECWFNPVM-------SEAELLMMTDHPNIISLLQVIETKKKLYLIMELCEGK----SLYQHIQ-- |. ...||.|. ..|....|. || ||||.| ||. .. . ||.... . .||||. |. . |.|...|..||.||| .|. .|. YHIGRKIGSGSFGCVYKCHHKGTGKIVAVKIIKKRH--EKSWKDQTHRRLSEIQIMKRLNHPNIVRLYDWFEDKDHIYMVMEYCEGGLYVMDLFDYISTW NAGYL--QEDEACPLFKQLLSAVNYCHNQGIVHRDLTPDNIMVEKDGKV----KIIDFGLGTQ--EKPAQKLNLFCENYPFSTPEVLLSRPYDMRKIDVW . | . .|.|.. ..|.|....|||..||.|||| |.||.. ..| . ||.|||| | . . . .. || ... |||.....|. .|.|.| RHGCFYFSEWECKFYMYQILRGLEYCHSMGIIHRDLKPENILIDNNGHIDACVKICDFGLAKQFDY-NNS-MTTFCGTPWYMAPEVIRGGQYYGPKVDMW GLGVVLYFMVTGKILFDAA------SIEKLRKQIVAGKCSVPCRLS---------------------VELQDLIRLLMTDNPELRPTVAEVMVHPWV ..|..|| |..|. .|. . . .. ..| .. . .. . |..|.|. . . .|. ||| .... |||. SCGCILYEMLCGRPPFPGHCWHDNHDQMQMICRIMGPPLHFDWPWWCSISYFFFRHWHFHWTFHNWSEECKDFIKWCLCKDPKKRPTAEQILQHPWF |
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| Kinase | MarkmA8.AA | Ciliate-E2 | 8-256 | 22 | 2.9e-71 | 243.07 | In-house | 1-365 (365) | Show / Hide |
Range on Protein: 8-256 Range on HMM: 1-365/365 Sequence Identity: 22% (85 aa) YEMLETIGQGGCAQVKLAQHRLTGTH-----------------------VAVKVIVKR--ECWFN--PVMSEAE----------LLMMTDHPNIISLLQV |. .. ||||. ..|......... .|.|.. |. | ... .| | . .| .||||| . . YKFIKKIGQGNFGSVYKCKVWKVQKQFAIKIIDQKQQRQQMQEKVKIKIYAMKIMKKNQIEQIKQEIHIMREINCFYKKINEKNILEQLNHPNIIKMYEC IE--TKKKLYLIMELCEGKSLYQHIQNA-----------GYLQEDEACPLFKQLLS---------------AVNYCHNQG-IVHRDLTPDNIMVEKDGKV . .....||.||.|.|..|...|.| .|. | |.. ..||.|. |..|.|... |.|||. |.||.. . FQEKDDNNIYLVMEYCQGGDLFDYIKNNKKKRNHEIEKDKYFTEKEIKYIMKQILQGFKTKAEFYIACIILALEYLHSKNNIIHRDIKPENILF-----I KIIDFGLGTQEKPAQKLNL--------------------------------FCENYPFSTPEVLLSRPYDM--------RKIDVWGLGVVLYFMVTGKIL ||||||| .. .. .. .. .| .... ||.| . .|| |.|.| |||.||.|..|| KIIDFGLSKKYDDDNQNRTHKQQCKWYMFKNDTSRTPGYMDQIIQQNMFNTICGTPGYMAPEILNGKKYDNQQKQKGYDYKCDIWSLGVILYEMLFGKPP FDAASIEKLRKQIVAGKCSVPCR------------------LSVELQDLIRL----LMTDNPELRPT-VAEVMVHPWV | .|| .|.. || .| | .|||. .. .|| |.| ... ||| F--------QQQIKQCKIDFPCPEWQKDTQCIQCKWKSWKKWSQECKDLIKKFGKRMLQKDPEKRITGWEQILNHPWF |
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| Kinase | MarkmA8.AA | SNRK | 8-256 | 39 | 7.8e-69 | 224.44 | In-house | 1-254 (254) | Show / Hide |
Range on Protein: 8-256 Range on HMM: 1-254/254 Sequence Identity: 39% (101 aa) YEMLETIGQGGCAQVKLAQHRLTGTHVAVKVIVKR---ECWFNPVMSEAELLMMTDHPNIISLLQVIETKKKLYLIMELCEGKSLYQHI-QNAGYLQEDE |.. .|.|.| | ||||.| || .|||||| | | .. | . . ||||. | ||.|. |||||.|| .| .| .| . |.|| YDLEKTLGRGHFAVVKLARHVFTGEKVAVKVIDKTKMDEVSKAHLFQEVRCMKLVQHPNIVRLYEVIDTQTKLYLILELGDGYDMYDYIMKHEKGLCEDL ACPLFKQLLSAVNYCHNQGIVHRDLTPDN-IMVEKDGKVKIIDFGLGTQEKPAQKLNLFCENYPFSTPEVLLSRPYDMRKIDVWGLGVVLYFMVTGKILF | |.|.. |..||| .||||| |.| . || | ||. ||| . .| .||. .| .| ||.|| || .|.| |||.|| .| |. | ARKYFCQIMHAIDYCHQLHVVHRDLKPENVVFFEKQGMVKLTDFGFSNKFMPGEKLETSCGSLAYSAPEILLGDSYDAPAVDIWSLGVILYMLVCGQAPF DAASIEKLRKQIVAGKCSVPCRLSVELQDLIRLLMTDNPELRPTVAEVMVHPWV . | .|. | .|| ..| | .||| .. .|. | .. |. |.|| QEANDSETLTMIMDCKYTVPDHVSDECRDLIQSMLVRDPKKRASLEEIVSHSWV |
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| Kinase | MarkmA8.AA | Ciliate-E2-Unclassified | 8-256 | 22 | 1e-66 | 227.96 | In-house | 1-352 (352) | Show / Hide |
Range on Protein: 8-256
Range on HMM: 1-352/352
Sequence Identity: 22% (81 aa)
YEMLETIGQGGCAQVKLAQHRLTGTHV-----AVKVIVKRECWFNPV---------MSEAE-------------LLMMTDHPNIISLLQVIETKKKLYLI
|.....||||| ..|...||. .. . . |.... . . . | . . .| . .||.|. .. . ..|...|..
YKIIKQIGQGGFGKVYKCQHKKQK-QYYAMKYMKKIQIYKQKQIMNKDEIMNEMKEMNNKKKYHQRKYNKIMQQILLNHPHPFIVKMFYCFQDKQNIYIV
MELCEGKSLYQHIQN-----------------AGYLQEDEAC-----PLFKQLLSAVNYCHNQG-IVHRDLTPDNIMVEKDG---KVKIIDFGLGTQEK-
||.|||..| |.|.. ..| .|. .|.|.|.. .|.| .. |.|||..|.||.. ..| ..||||||. . .
MEYCEGGDLWQYIKKRKKQKQKGNDLFHNMKQRKIFTEQQAKYKKAKFYFAQILQGLEYLHHKNNIIHRDIKPENILFDNNGKNYYIKIIDFGISKKYQQ
---------------PAQKLNLFCENYPFS----TPEVLLSRPYDMR---KIDVWGLGVVLYFMVTGKILFDAASIEK----------------LRKQIV
. |... || .. . |||| . || . |.|.|.|||.||.|..|. |.. . |. |...|
NNNCDTNQQQKMQIWKQQMMWTFCGTPNYMPQYTAPEVLQGQNYDHSKAYKCDIWSLGVILYEMLFGYYPFYDNNCEQHQQLITQWINNAYRKQLYQNIK
AGKCSVPC--------RLSVELQDLIR----LLMTDNPELRPTVAEVMVHPWV
......|. ..| | .|.|. .. ||. |.| ... |||
QKNIQFPKFPWQQIPKHWSPEAKDFINDLLQKMLKKNPNKRITFEQILNHPWF
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| Kinase | MarkmA8.AA | MELK | 8-256 | 34 | 2.1e-59 | 201.59 | In-house | 1-254 (254) | Show / Hide |
Range on Protein: 8-256 Range on HMM: 1-254/254 Sequence Identity: 34% (87 aa) YEMLETIGQGGCAQVKLAQHRLTGTHVAVKVIVKRECWFN--PVMSEAELLMMTDHPNIISLLQVIETKKKLYLIMELCEGKSLYQHIQNAGYLQEDEAC ||. ..|| || |.|||| | ||. .||.|.. |.. . | | . | | .| | .|||..|....|| | | .. .| |.|.|. YEVHDEIGTGGFAKVKLACHILTNQMVAIKIMDKNQLGHDLPRVKTEMDALKNLRHQHICQLYHYIETEDKIFMVMEYCPGGEMFDYIIRQDRLEEEETR PLFKQLLSAVNYCHNQGIVHRDLTPDNIMVEKDGKVKIIDFGLGTQEKPAQ---KLNLFCENYPFSTPEVLLSRPYDMRKIDVWGLGVVLYFMVTGKILF .|.|..||. | | || |||| |.|.... | ..|.||||| . | . .|. | . ||.. . | ||| .|..|| .. | . | HFFRQIVSAIAYVHSQGYAHRDLKPENLLFDEDHHLKLIDFGLCAKTKGRKDYHNLQTCCGSPAYAAPELIQGKQYIGSEADVWSMGILLYVLMCGFLPF DAASIEKLRKQIVAGKCSVPCRLSVELQDLIRLLMTDNPELRPTVAEVMVHPWV | .. . |.|. |. .| ||.| ..|.| .. .|. | . ... |||| DDDNMMIMYKKIMSGCYEEPKWLSPESKQLLRHMLQVDPKKRISMKNLLNHPWV |
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| Kinase | MarkmA8.AA | RSK | 10-256 | 31 | 1.2e-58 | 201.12 | In-house | 1-278 (278) | Show / Hide |
Range on Protein: 10-256 Range on HMM: 1-278/278 Sequence Identity: 31% (88 aa) MLET--IGQGGCAQVKLAQHRLTGTHVAVKVIVKRECWFNPV-----MSEAELLMMTD-HPNIISLLQVIETKKKLYLIMELCEGKSLYQHIQNAGY--- . . .|.| ... .|. ||.. |.||. |.. . . | | . |... ||.|..| . .|..|||||||.|.| |. |.|. .. LKVLGQGGYGKVFLCRKCTHHDTGQIYAMKVLKKAKIVQRQKDTRHTMTERNILERCQQHPFIVTLHYAFQTEGKLYLIMEYCRGGELFTHLQKEKHFGC LQEDEACPLFKQLLSAVNYCHNQGIVHRDLTPDNIMVEK---DGKVKIIDFGLGTQEKPA--QKLNLFCENYPFSTPEVLL---SRP-YDMRKIDVWGLG . ||||| . .. .|| . | |||.|||| |.||. . .| .|..|||. | .. |... || . ||.| . .| . |.| || FSEDEACFYMAEIVLAVEHLHQQGIIHRDLKPENILYDDESNEGHIKLTDFGFCKQFRCDHNQWTMTFCYTIEYMAPEMLKRANQQGGHD-KACDWWSLG VVLYFMVTGKILFDA---ASIEKLRKQIVAGK--CSVP--CRLSVELQDLIRLLMTDNPELRPT-----VAEVMVHPWV |..| | ||. | . .. ... |.| || . | || | .|||| ... .|. |.. ..|. ||| VLMYEMLTGCPPFQGPNDNNRKEIMKRIQKGKFSLTMPNWQYLSQEAKDLIRKMLHRDPHKRLGCGPQDAEEIKQHPWF |
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| Kinase | MarkmA8.AA | Pkinase_Tyr | 8-148 | 25 | 7.1e-17 | 57.78 | Pfam | 1-157 (270) | Show / Hide |
Range on Protein: 8-148 Range on HMM: 1-157/270 Sequence Identity: 25% (41 aa) YEMLETIGQGGCAQVKLAQHR----LTGTHVAVKVIVKRECWFNP-----VMSEAELLMMT-DHPNIISLLQVIE-TKKK--LYLIMELCEGKSLYQHIQ ......|.| .|... . |...||||.. | . |.||.... .||||..|. |. .. .|..||.... .|. . . ITFGKKLGEGAFGEVYKGTWKGDPDNTKIPVAVKML-KEGAMHEQNCREDFMREAKIMKQLGHHPNIVRLYGVCTDQGEPNQIYIVMEYMPHGDLLDYLR NAGYLQEDEACPLFKQLLS-------AVNYCHNQGIVHRDLTPDNIMVEKDGKVKIIDFGL . ||. . |.||. . .| ......|||| |..|.....||| |||| KHR---EDKQPLTMKDLLQMCWQIAKGMEYLESKNCIHRDLAARNCLVTENNVVKICDFGL |
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| Kinase | MarkmA8.AA | TyrKc | 8-255 | 20 | 8.4e-14 | 0.46 | SMART | 1-280 (280) | Show / Hide |
Range on Protein: 8-255 Range on HMM: 1-280/280 Sequence Identity: 20% (58 aa) YEMLETIGQGGCAQVKLAQHRLTGTHVAVKVIVKRECWFNPVMSEAELLMMT--DHPNIISLLQVIETK-------KKLYLIMELCEGKSLYQHIQNAGY ......| | .| ... . . ||||.. . |.||..... .||||. |. |. .. . |...||.... .| ..... . ITLGKKLGEGAFGEVYKGTWK---IQVAVKMLKEDA--REDFMREARIMCKLGGHHPNIVRLYGVCTQQGRNFMYIEPLMIVMEYMPHGDLKDYLRKHRP -LQEDEACPLFKQLLSAVNYCHNQGIVHRDLTPDNIMVEKDGKVKIIDFGLGTQEKPA------QKLNLF----CEN--YPF--STPEVLLSRPYDMRKI |. .. . | . .| | ....|||| |..| ... ||| |||| . .. ... | ||.. . . | KLCMKDLLSFCWQIACGMEYLHSKNCIHRDLAARNCLVGENHTVKISDFGLSRDIYDDDQQGESKDYYRKKEHKGGKTMLPIRWMAPECINYGKFTT-KS DVWGLGVVLYFMVT-GKILFDA-----ASIEKLRKQIVAG-KCSVPCR--------LSVELQDLIRLLMTDNPELRPTVAEVMVHPW ||| ||... . | |. | . ..... .| | . |. .... .|| ||| .|. .. . DVWSFGVCMWEIFTYGQQPYPGMIQQMMSNQEVIEYVKQGYRMPQPPNDYPMSFVCCPDEMYQIMKQCWHEDPEDRPTFSEI-HECF |
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| UBA_CAMKL | MarkmA8.AA | UBA_CAMKL | 276-313 | 39 | 8.7e-12 | 40.45 | In-house | 1-41 (41) | Show / Hide |
Range on Protein: 276-313 Range on HMM: 1-41/41 Sequence Identity: 39% (16 aa) DPAIVKAMGYI--GFRAQEIEDSLRQRKF-NETMASYCLLK |. |.. | . || .||..|||..|. |. .| |.|| DEEIIQEMCKMWHGFDREEIIESLRNNKYHNHITATYYLLL |
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