Gene MarkmB1 (Mouse)

MarkmB1

Species: Mouse
Alias: MarkmB1
External Links:
Annotation:

Classification

Group: CAMK
Family: CAMKL
Subfamily: MARK

Sequence

Name Sequence Type Origin Length Description Download
MarkmB1.kin_dom Protein Kinase Domain Sugen global kinase HMM prediction 249 Kinase domain by global Sugen HMM Fasta, JSON
MarkmB1.NA RNA Sugen 4560 None Fasta, JSON
MarkmB1.AA Protein Sugen 499 None Fasta, JSON

Protein domain

Protein domains of MarkmB1.AA. The domains are annotated by HMM profiles from Pfam and SMART, as well as in-house data which includes HMMs of each individual kinase group, family and subfamily. Here is domain list in details, including sequence identity, significance and alignment. In particular, you can find can find the best hit kinase group/family/subfamily, which is helpful to understand the relationship between kinases.Kinase domain and best hit kinase group/family/subfamily are highlighted in red and blue. Visualized by pviz.

Usage: Zoom in selected region by dragging mouse and zoom out by double-clicking.

Show/hide domain list
Domain Protein name Domain Name Range Identity (%) Significance Score Profile Source Profile Range (length) Alignment
Kinase MarkmB1.AA MARK 14-262 53 8.8e-164 539.06 In-house 1-262 (262) Show / Hide 
Range on Protein: 14-262
Range on HMM: 1-262/262
Sequence Identity: 53% (139 aa)

YKVLFTLGHGSFGTVKLACHLKTKALVAIKMVE---LSK-KNIRGIRAEIATLEKLQHPNIICLFQVLV--TSKH-INIVTEYIPGGNLFDIIKED--GP
||.| |.||||...||||||..|.  ||||..|   |.. .... .. ||. . ||.|||||.||.| .  |..| |... ||..||.|.| ||.   |.
YKMLKTIGHGSYAKVKLACHKHTGRKVAIKIYEKFKLNDPQWMKNVMREIEIMKKLDHPNIIKLFHVIEQDTEQHQIYLIMEYASGGELYDYIKAHPNGR

MHEEEARRIFGQVVSAVKYCHNQDIVHQDIKAQNILRDEEG--NVKIIDFGLAIRCRSGTLLKRQCGTKSCFAPELVLQEPYDGKKADVWSLGVLLYFIT
.||||||||| |.||||.|||...||| |||..||| ||.|  |.||||||..|.. .|..|.. |||... |||..|..||||.|.|.|||||.|||..
LHEEEARRIFRQIVSAVNYCHSKNIVHRDIKPENILIDENGNHNIKIIDFGFSICIPPGQKLNTFCGTPPYMAPEIFLKKPYDGPKVDIWSLGVVLYFMV

TGYYPFRGST--MKEMEEKIATGTYDIPTHVSGQLENLIHQILTVPPEMRPSIEDIERHPWV
.||.||.|.|  .||...|| .| ||||.||| ...|||...|||.||.||.||.|..|||.
CGYFPFDGDTQDYKELYKKILRGKYDIPCHVSKECRNLIQRLLTVNPEERPTIEEIMKHPWM
Kinase MarkmB1.AA CAMKL 14-262 39 3.2e-137 440.53 In-house 1-297 (297) Show / Hide 
Range on Protein: 14-262
Range on HMM: 1-297/297
Sequence Identity: 39% (119 aa)

YKVLFTLGHGSFGTVKLACH-LKTKALVAIKMVELSKKN-IRGIRA---------------EIATLEKLQ---HPNIICLFQVLVTSKH------INIVT
|... |||.||||.||||.| . |.  ||||... .|.. .  ...               ||. ...|.   ||||| |..|. |..|      |..|.
YRIGKTLGKGSFGKVKLATHIRTTGEKVAIKIIDKKKIWNDPWMKKNKCGQKHESDMRIRREIQIMKMLNIGKHPNIIKLYEVIETPEHDIETKKIYLVM

EYIPGGN--LFDIIKED----GPMHEEEARRIFGQVVSAVKYCHNQDIVHQDIKAQNILRDEEG--NVKIIDFGLAIRCRS-----GTLLKRQCGTKSCF
||..||.  ||| |..     |.|.|.||||.| |.||||.|||...||| |||. ||| || |  |.||||||... .|      | .|| .||. .  
EYCSGGEMDLFDYIVKHGHRRGRMPEHEARRYFRQIVSAVNYCHSHGIVHRDIKPENILLDENGNNNIKIIDFGFSNMYRPCIFGPGQKLKTFCGSPPYM

APELVLQ--EPYDGKKADVWSLGVLLYFITTGYYPFRGSTMK---------EMEEKIATGTYDIPTHVSGQLENLIHQILTVPPEMRPSIEDIERHPWV
|||...   .||||.|.|.||.||.||.. .||.||.. |..         . ....  . ..|. ||| ....||...|.| || ||.|..|..|||.
APEIFQGNNKPYDGPKVDIWSCGVILYAMVCGYLPFDDDTYNKQGKDNIYLYWKIMCG-YYPPIWYHVS-DCRDLIRKMLQVNPEKRPTIHQIMNHPWM
Kinase MarkmB1.AA CAMK 19-262 27 1.1e-113 367.86 In-house 1-425 (425) Show / Hide 
Range on Protein: 19-262
Range on HMM: 1-425/425
Sequence Identity: 27% (117 aa)

TLGHGSFGTVKLACHLKTK------------ALVAIKMVELS-----------------------------KKNIRGIRAEIATLEKLQ-------HPNI
|||.||||.|||..| .|.              ||||... .                              |. . .| ||. . |||       ||||
TLGRGSFGKVKLCIHKNTTGKERVHHIYTNGQKVAIKIIDKKKLKDKQNQDYSNCYKIDKSKCKHRYCWRRPKDRKNVRREIEIMKKLQGIGNKLDHPNI

ICLFQVLV------------TSKH--------INIVT---EYIPGG----NLFDIIKEDGP---------------MHEEEARRIFGQVVSAVKYCHNQD
| |..|              | ..        . .|.   ||..||     ||| |.| |.               ..|.||||.| |..|||.|||...
IKLYEVYEDPHYFKNTNDYET-SKQVFTKDKHMYMVMEIMEYCSGGELFDDLFDYIVEHGCYGEEFDQFDIVERGRFTEREARRYFRQICSAVHYCHSHN

IVHQDIKAQNILRDEE-----------------GNVKIIDFGLAIRCRS------------------------GTLLKRQCGTKSCFA-PELVLQ-----
||| |.|  ||| |.                  .|.||||||.|.....                        | ..| .||| .  | ||....     
IVHRDLKPENILLDDNNDDSDPVEHDEIFDWNNNNIKIIDFGFANKFDPGENNFMCSDYKGGEMHNQWTTPTEGQKMKTFCGTPEYMAAPEVLNGKGHCN

--------EPYDGKKADVWSLGVLLYFITTGYYPFRGS-------------TMKEMEEKIATGTYD-IPTHVSG-----------------------QLE
        .||.|.|.|.||.||.||.  .||.||.|.             ...|. ||| .| || .| ..|.                       .  
MQNATDEEKPYYGPKCDMWSCGVILYIMLCGYPPFYGDCDNEICEDEWIGMNDYELFEKIMKGKYDFPPPYFSPISCNYGPEWWDDISDEFHHFVSQECK

NLIHQILTVPPEMRPSIEDIERHPWV
.|| ..|.| || |..||.. .|||.
DLIRKMLQVDPEKRMTIEQCLNHPWM
Kinase MarkmB1.AA NuaK 14-262 41 1.8e-91 240.71 In-house 1-252 (252) Show / Hide 
Range on Protein: 14-262
Range on HMM: 1-252/252
Sequence Identity: 41% (105 aa)

YKVLFTLGHGSFGTVKLACHLKTKALVAIKMVELSK----KNIRGIRAEIATLEKLQHPNIICLFQVLVTSKHINIVTEYIPGGNLFDIIKEDGPMHEEE
|... ||| | .| ||||   .|  .|||| .  .|    . .. || ||  .  |.||.||  . |   .  | || ||  ||.|.| | | . . |.|
YEFQKTLGKGTYGKVKLATEHSTGREVAIKSIKKCKIEDEQDMVHIRREIEIMSSLNHPHIIHIYEVFENKDKIVIVMEYASGGELYDYISECKSLPERE

ARRIFGQVVSAVKYCHNQDIVHQDIKAQNILRDEEGNVKIIDFGLAIRCRSGTLLKRQCGTKSCFAPELVLQEPYDGKKADVWSLGVLLYFITTGYYPFR
||..| |.|||| |||   |.| | |  ||| |...|.|| ||||      . .|.  ||      || |  .|| |   | |||||||| .  |  || 
ARHFFRQIVSAVHYCHKHRICHRDLKLENILLDQNCNAKIADFGLSNYYHDQKFLHTFCGSPLYASPEIVNGQPYHGPEVDCWSLGVLLYTMVYGTMPFD

GSTMKEMEEKIATGTYDIPTHVSGQLENLIHQILTVPPEMRPSIEDIERHPWV
|.  |..   |  | |  |.. | . . || ..|.| |. | .|.||  |.||
GHDFKHLVKQISQGAYYEPCKPSDACM-LIRWMLMVNPRRRATIYDICHHWWV
Kinase MarkmB1.AA AMPK 14-262 40 1e-88 263.51 In-house 1-254 (254) Show / Hide 
Range on Protein: 14-262
Range on HMM: 1-254/254
Sequence Identity: 40% (102 aa)

YKVLFTLGHGSFGTVKLACHLKTKALVAIKMVE----LSKKNIRGIRAEIATLEKLQHPNIICLFQVL-VTSKHINIVTEYIPGGNLFDIIKEDGPMHEE
| .  |.| |.|| ||.. |  |.  ||||  .     ...    |. ||  | .. ||.|| |..|.  | . | .|.||..|| ||| |   | . |.
YIIGKTIGEGTFGKVKMGTHILTGEKVAIKILNKQKIKDQDMVERIQREIHILKLFRHPHIIQLYEVIIETPTDIFMVMEYVSGGELFDYIVKHGRLQER

EARRIFGQVVSAVKYCHNQDIVHQDIKAQNILRDEEGNVKIIDFGLAIRCRSGTLLKRQCGTKSCFAPELVLQEPYDGKKADVWSLGVLLYFITTGYYPF
||.| | |..|.| |||.  ||| | |  |.| |.. |.|| ||||   .  | .||  ||     |||..   .| | . |.|| || ||    || ||
EACRFFQQIISGVEYCHRHMIVHRDLKPENLLLDHNKNIKIVDFGLSNMMKDGEFLKTACGSPCYAAPEMISGKLYCGPEVDIWSCGVILYAMLCGYLPF

RGSTMKEMEEKIATGTYDIPTHVSGQLENLIHQILTVPPEMRPSIEDIERHPWV
  .   .   ||  | | ||...| . ..||...|.| |. | .|.||  ||| 
DDENTPTLYKKIKNGEYYIPKFLSPEAKDLIKHMLQVDPMKRITIHDIRNHPWF
Kinase MarkmB1.AA S_TKc 14-262 35 3.6e-87 296.8 SMART 1-231 (231) Show / Hide 
Range on Protein: 14-262
Range on HMM: 1-231/231
Sequence Identity: 35% (94 aa)

YKVLFTLGHGSFGTVKLACHLKTKALVAIKMVELSKKNIRGIRAEIATLEKLQHPNIICLFQVLVTSKHINIVTEYIPG--GNLFDIIKEDGP------M
|..| ..|.|.||.|... | ||. .||||..       . || ||. |.| .||||. |. | .. .|. .|.||..|  |.|||.||. |.      .
YEILRKIGKGAFGKVYKCRHKKTGRIVAIKIIK------EHIRREIQILKK-HHPNIVKLYDVFQD-DHLYMVMEYCDGDLGDLFDYIKKRGRHGLRFPF

HEEEARRIFGQVVSAVKYCHNQDIVHQDIKAQNILRDEEGNVKIIDFGLAIRCRSGTLLKRQCGTKSCFAPELVLQEPYDGKKADVWSLGVLLYFITTGY
.| .||... |...|..|||.. |.| |.| .||| ||  ..||.||||| .       . .|||    |||..   .|...|.|.||.|..||   .||
PE-HARFYMYQICCALEYCHSHGIIHRDLKPENILLDE--HIKICDFGLARQL------TTFCGTPWYMAPEVL---GYGKCKCDWWSCGCILYEMLCGY

YPFRGSTMKEMEEKIATGTYDIPTHVSGQLENLIHQILTVPPEMRPSIEDIER-------HPWV
 ||.  .|..| .||           | .. ..| ..|.. || ||.. .. .       |||.
PPFP--QMQMMFKKIG----------SPEAKDFIRKCLQKDPEKRPTA-EALQDEWDIKCHPWF
Kinase MarkmB1.AA QIK 14-262 39 7e-87 294.95 In-house 1-272 (272) Show / Hide 
Range on Protein: 14-262
Range on HMM: 1-272/272
Sequence Identity: 39% (107 aa)

YKVLFTLGHGSFGTVKLACHLKTKALVAIKMV---ELSKKNIRGIRAEIATLEKLQHPNIICLFQVLVTSKHINIVTEYIPGGNLFDIIKEDGP------
| .  |.| | |..|||| |  ||. |||| .    | ..|.  .  |.. .  |.||.|| |.||. | . . ||||| ..| .|| . . |       
YDIERTIGKGNFAVVKLARHRITKTKVAIKIIDKSQLDEENLQKCYREVQIMKMLYHPHIIKLYQVMETDDMMYIVTEYCSNGEMFDYLCKHGRKGVKMV

--------------MHEEEARRIFGQVVSAVKYCHNQDIVHQDIKAQNILRDEEGNVKIIDFGLAIRCRSGTLLKRQCGTKSCFAPELVLQEPYDGKKAD
              | |.||||.| |..|||.|||.. ||| |.|| ||| |.. |.||.|||.     .| ||.  ||.    |||. . . ||| |.|
NSPDIGDQVLMGVPMAENEARRWFWQICSAVHYCHKRNIVHRDLKAENILLDNNMNIKIADFGFSNWFKQGQLLMTWCGSPPYAAPEMFEGKEYDGPKVD

VWSLGVLLYFITTGYYPFRGSTMKEMEEKIATGTYDIPTHVSGQLENLIHQILTVPPEMRPSIEDIERHPWV
.||.||.||   .|  || |.|.... ...  | . ||  .|  .| || . |.| || | .|. | .|.| 
IWSMGVVLYVLVCGALPFDGKTLQNLRQRVLSGKFRIPFFMSQDCEHLIRHMLVVDPEHRYTIMQICQHRWM
Kinase MarkmB1.AA NIM1 14-262 38 2.6e-80 235.61 In-house 1-258 (258) Show / Hide 
Range on Protein: 14-262
Range on HMM: 1-258/258
Sequence Identity: 38% (99 aa)

YKVLFTLGHGSFGTVKLACHLKTKALVAIKMVE-----LSKKNIRGIRAEIATLEKLQHPNIICLFQVLVTSKHINIVTEYIPGGNLFDIIKEDGPMHEE
| .   .| | |  |||. |  ||  |||| .      .  |  |    ||...|.. ||||. |. |  |   .  |.||..|| |.  | . |.. | 
YRFCGEIGRGNFSKVKLGVHQLTKEKVAIKIMDLDKTKMDQKTQRMLSREIQCMECMHHPNIVRLYEVVETLTRVHLVMEYARGGELYTHIHQEGKLREI

EARRIFGQVVSAVKYCHNQDIVHQDIKAQNILRDEEGNVKIIDFGLAIRCRS----GTLLKRQCGTKSCFAPELVLQEPYDGKKADVWSLGVLLYFITTG
..  || |.|||||  | ..||| |||| |..   .. ||. |||    |      .  |   ||     ||||   | | |   ||| ||.||||  ||
HCKPIFAQIVSAVKHMHSRNIVHRDIKAENVMYTSNNCVKVGDFGFSCYCKMGTGANQMLNTFCGSPPYAAPELFQDEHYIGEYVDVWALGILLYFMMTG

YYPFRGSTMKEMEEKIATGTYDIPTHVSGQLENLIHQILTVPPEMRPSIEDIERHPWV
  |||  |  .|   |  |.| || .||     ||  .|  .|  |. |...  | |.
VMPFRAETVPKMKKCILKGQYQIPDYVSLPCHRLIRGMLKHIPTQRYTIDQMMNHQWM
Kinase MarkmB1.AA Pkinase 14-262 28 2.1e-75 261.62 Pfam 1-293 (293) Show / Hide 
Range on Protein: 14-262
Range on HMM: 1-293/293
Sequence Identity: 28% (85 aa)

YKVLFTLGHGSFGTVKLACHLKTKALVAIKMVELSKKNIRGIRA-----EIATLEKLQHPNIICLFQVLVTSKHINIVTEYIPGG----NLFDIIK--ED
|... ..| ||||.|....| .|  .||.| .......    ..     ||. . .|.||||. |. .  ...|| .|.|| .||     |||.|.  ..
YHIGRKIGSGSFGCVYKCHHKGTGKIVAVKIIKKRHEKSWKDQTHRRLSEIQIMKRLNHPNIVRLYDWFEDKDHIYMVMEYCEGGLYVMDLFDYISTWRH

GPM--HEEEARRIFGQVVSAVKYCHNQDIVHQDIKAQNILRDEEGNV----KIIDFGLAIR--CRSGTLLKRQCGTKSCFAPELVLQEPYDGKKADVWSL
|..   |.|..... |......|||.. |.| |.| .||| |..|..    ||.|||||      ... ..  |||    |||...  .|.|.|.|.||.
GCFYFSEWECKFYMYQILRGLEYCHSMGIIHRDLKPENILIDNNGHIDACVKICDFGLAKQFDY-NNS-MTTFCGTPWYMAPEVIRGGQYYGPKVDMWSC

GVLLYFITTGYYPFRGS------TMKEMEEKIATGTYDIPTHVS---------------------GQLENLIHQILTVPPEMRPSIEDIERHPWV
|..||   .|. ||.|.      ....| ..|  . .. .   .                       .  .|  .|.. |. ||..|.|  |||.
GCILYEMLCGRPPFPGHCWHDNHDQMQMICRIMGPPLHFDWPWWCSISYFFFRHWHFHWTFHNWSEECKDFIKWCLCKDPKKRPTAEQILQHPWF
Kinase MarkmB1.AA MELK 14-262 38 2.4e-68 232.61 In-house 1-254 (254) Show / Hide 
Range on Protein: 14-262
Range on HMM: 1-254/254
Sequence Identity: 38% (97 aa)

YKVLFTLGHGSFGTVKLACHLKTKALVAIKMVELSK--KNIRGIRAEIATLEKLQHPNIICLFQVLVTSKHINIVTEYIPGGNLFDIIKEDGPMHEEEAR
|.|  ..| | |. ||||||. |   ||||...  .  ...  ...|.  | .|.| .|  |. .. | . | .| || |||..|| | .   ..|||.|
YEVHDEIGTGGFAKVKLACHILTNQMVAIKIMDKNQLGHDLPRVKTEMDALKNLRHQHICQLYHYIETEDKIFMVMEYCPGGEMFDYIIRQDRLEEEETR

RIFGQVVSAVKYCHNQDIVHQDIKAQNILRDEEGNVKIIDFGLAIRCRSGTLLKR----QCGTKSCFAPELVLQEPYDGKKADVWSLGVLLYFITTGYYP
 .| |.|||. | | |   |.|.| .|.| ||. ..|.|||||  .   |   .      ||     ||||.    | |  |||||.|.||| .  |. |
HFFRQIVSAIAYVHSQGYAHRDLKPENLLFDEDHHLKLIDFGLCAKT-KGRKDYHNLQTCCGSPAYAAPELIQGKQYIGSEADVWSMGILLYVLMCGFLP

FRGSTMKEMEEKIATGTYDIPTHVSGQLENLIHQILTVPPEMRPSIEDIERHPWV
|    |. |  ||  | |. | ..| .  .|....| | |. | |. ..  ||||
FDDDNMMIMYKKIMSGCYEEPKWLSPESKQLLRHMLQVDPKKRISMKNLLNHPWV
Kinase MarkmB1.AA CAMK-Unique 14-262 23 5.6e-67 220.09 In-house 1-363 (363) Show / Hide 
Range on Protein: 14-262
Range on HMM: 1-363/363
Sequence Identity: 23% (86 aa)

YKVLFTLGHGSFGTVKLACHLKTKALVAIKMVEL-SKKNIRGIR--------------------AEIATLEKLQHPNIICLFQV----LVTSK-------
|| .  .|||.|| |. .   .|. . |.|||..   .|....                      |.. . .. ||||| |...     ...|       
YKMHRIIGHGNFGHVYECMDRETGKKWACKMVKKQTHGNKKQKQQRNFDLRYKITEKRRDMKLKREHQIWKMVDHPNIIKLYDWNNPIFCDRKYPLCDLI

--------HINIVTEYIPGGNLFDIIKE--------------------DGPMHE--EEARRIFGQVVSAVKYCHNQDIVHQDIKAQNILRDEEGN-----
        .. ||.||..|| |||.| .                     |.. |   ....|. ...|||.| |.||||| |.|. ||.  ....     
IKTPRALPYMYIVMEYCQGGDLFDWIQKWDEFYFNFIIKFDFNILKRCQGHFSERCWDTCFIMQCLLSAVAYMHSQDIVHRDLKLENIMVCYSFKDNNHH

-----------VKIIDFGLAIRCR-SGTL--LKRQCGTKSCFAP--------------ELVLQEPYDGKKA---DVWSLGVLLYFITTGYYPFRGSTMK-
           .|..||||.   . .     ..  ||| .  ||              |.. . .||..     | |||||..|.  .|. || ... . 
RDFPYDWSNWHIKLCDFGLCCHYNHNKMCHMMQTMCGTPCYMAPEIVFCKNYQEMTRDEVINMQCYDQQCSPASDIWSLGVIMYYMLCGCPPFDCECEDR

-------EMEEKIATGTY--------DIPTHVSGQLENLIHQILTVPPEMRPSIEDIERHPWV
       | .|.|  | |        ..|  .| .. ... . .|| |  | |.. .. |.|.
DYENHDKEIFECICKGDYCNFDWKMWHGPDYISQEAKDFVKCCMTVDPDHRWSAKELLEHQWI
Kinase MarkmB1.AA Ciliate-E2 14-262 24 8.8e-67 228.17 In-house 1-365 (365) Show / Hide 
Range on Protein: 14-262
Range on HMM: 1-365/365
Sequence Identity: 24% (92 aa)

YKVLFTLGHGSFGTVKLACHLKTKALVAIK---------------------MVELSKKNIRGIRAEIATL----------------EKLQHPNIICLFQV
||..  .| |.||.|..... |.. ..|||                     |  ..|..|. |  ||  .                |.|.||||| .. .
YKFIKKIGQGNFGSVYKCKVWKVQKQFAIKIIDQKQQRQQMQEKVKIKIYAMKIMKKNQIEQIKQEIHIMREINCFYKKINEKNILEQLNHPNIIKMYEC

LV--TSKHINIVTEYIPGGNLFDIIKED-----------GPMHEEEARRIFGQVVS---------------AVKYCHNQD-IVHQDIKAQNILRDEEGNV
    . ..| .|.||. ||.|||.||.            ... |.|...|. |...               |..|.|..  |.| ||| .|||      .
FQEKDDNNIYLVMEYCQGGDLFDYIKNNKKKRNHEIEKDKYFTEKEIKYIMKQILQGFKTKAEFYIACIILALEYLHSKNNIIHRDIKPENILF-----I

KIIDFGLAIRCRSG--------------------------------TLLKRQCGTKSCFAPELVLQEPYDG--------KKADVWSLGVLLYFITTGYYP
|||||||. ..                                    . ...|||    ||| .  ..||.        .|.|.|||||.||.  .|..|
KIIDFGLSKKYDDDNQNRTHKQQCKWYMFKNDTSRTPGYMDQIIQQNMFNTICGTPGYMAPEILNGKKYDNQQKQKGYDYKCDIWSLGVILYEMLFGKPP

FRGSTMKEMEEKIATGTYDIP------------------THVSGQLENLIHQ----ILTVPPEMRPS-IEDIERHPWV
|        ...|  . .|.|                   ..| .  .|| .    .| . || |.. .|.|  ||| 
F--------QQQIKQCKIDFPCPEWQKDTQCIQCKWKSWKKWSQECKDLIKKFGKRMLQKDPEKRITGWEQILNHPWF
Kinase MarkmB1.AA Pkinase_Tyr 14-155 29 2.7e-17 59.19 Pfam 1-158 (270) Show / Hide 
Range on Protein: 14-155
Range on HMM: 1-158/270
Sequence Identity: 29% (46 aa)

YKVLFTLGHGSFGTVKLACHL----KTKALVAIKMV--ELSKKN--IRGIRAEIATLEKL-QHPNIICLFQVLV-TSKH--INIVTEYIPGGNLFDIIKE
 . . .||.|.||.|...       .||  ||.||.    ....  ..   .|.... .| .||||..|  | .  ...  | ||.|| |.|.| |  ..
ITFGKKLGEGAFGEVYKGTWKGDPDNTKIPVAVKMLKEGAMHEQNCREDFMREAKIMKQLGHHPNIVRLYGVCTDQGEPNQIYIVMEYMPHGDLLDYLRK

----DGPMHEEEARRIFGQVVSAVKYCHNQDIVHQDIKAQNILRDEEGNVKIIDFGLA
    ..|   ..   .  |. ..  | ... ..| |. | |.| .|.. ||| |||||
HREDKQPLTMKDLLQMCWQIAKGMEYLESKNCIHRDLAARNCLVTENNVVKICDFGLA
Kinase MarkmB1.AA TyrKc 14-262 24 1.2e-15 30.12 SMART 1-280 (280) Show / Hide 
Range on Protein: 14-262
Range on HMM: 1-280/280
Sequence Identity: 24% (71 aa)

YKVLFTLGHGSFGTVKLACHLKTKALVAIKMVELSKKNIRGIRAEIATLEKL--QHPNIICLFQVLVTS-------KHINIVTEYIPGGNLFDIIKEDGP
 . . .||.| ||.| ..        ||.||.  ..  .. .. |.  . ||  .||||..|. | ...       . . ||.|| |.|.| | ... .|
ITLGKKLGEGAFGEVYKGTWK---IQVAVKMLKEDA--REDFMREARIMCKLGGHHPNIVRLYGVCTQQGRNFMYIEPLMIVMEYMPHGDLKDYLRKHRP

-MHEEEARRIFGQVVSAVKYCHNQDIVHQDIKAQNILRDEEGNVKIIDFGLAIRCRSG------TLLKRQCGTKSCF--------APELVLQEPYDGKKA
    ..   .  |. .   | | . ..| |. | |.| .|.. ||| ||||.    ..      .  .|. ..|..         |||      .   | 
KLCMKDLLSFCWQIACGMEYLHSKNCIHRDLAARNCLVGENHTVKISDFGLSRDIYDDDQQGESKDYYRKKEHKGGKTMLPIRWMAPECINYGKFT-TKS

DVWSLGVLLY-FITTGYYPFRG-----STMKEMEEKIATG-TYDIPTH--------VSGQLENLIHQILTVPPEMRPSIEDIERHPWV
|||| ||...   | |  |  |      . .|. |.. .|   ..| .         .  . ... |     ||.||. ..|  |   
DVWSFGVCMWEIFTYGQQPYPGMIQQMMSNQEVIEYVKQGYRMPQPPNDYPMSFVCCPDEMYQIMKQCWHEDPEDRPTFSEI--HECF
Kinase MarkmB1.AA Pkinase_Tyr 188-199 66 0.48438 4.15 Pfam 194-205 (270) Show / Hide 
Range on Protein: 188-199
Range on HMM: 194-205/270
Sequence Identity: 66% (8 aa)

KADVWSLGVLLY
| |||| |||..
KSDVWSFGVLMW
UBA_CAMKL MarkmB1.AA UBA_CAMKL 276-313 43 6.7e-11 37.29 In-house 1-41 (41) Show / Hide 
Range on Protein: 276-313
Range on HMM: 1-41/41
Sequence Identity: 43% (18 aa)

DYNIIEMLCGM--GFDANEILESLQRKKY-NESMGAYLILK
| .||. .| |  ||| .|| |||.  || |. ...|..| 
DEEIIQEMCKMWHGFDREEIIESLRNNKYHNHITATYYLLL
UBA MarkmB1.AA UBA 276-313 26 5e-06 27.22 SMART 1-38 (38) Show / Hide 
Range on Protein: 276-313
Range on HMM: 1-38/38
Sequence Identity: 26% (10 aa)

DYNIIEMLCGMGFDANEILESLQRKKYNESMGAYLILK
.  .|..|..|||| .|....|.. ..|. | ..... 
YEEKIDQLMEMGFDREECVQALRACNWNVEMAMNWLFS