Gene MarkmB3 (Mouse)
MarkmB3
Sequence
| Name | Sequence Type | Origin | Length | Description | Download |
|---|---|---|---|---|---|
| MarkmB3.kin_dom | Protein Kinase Domain | Sugen global kinase HMM prediction | 249 | Kinase domain by global Sugen HMM | Fasta, JSON |
| MarkmB3.NA | RNA | Sugen | 1482 | None | Fasta, JSON |
| MarkmB3.AA | Protein | Sugen | 493 | None | Fasta, JSON |
Protein domains of MarkmB3.AA. The domains are annotated by HMM profiles from Pfam and SMART, as well as in-house data which includes HMMs of each individual kinase group, family and subfamily. Here is domain list in details, including sequence identity, significance and alignment. In particular, you can find can find the best hit kinase group/family/subfamily, which is helpful to understand the relationship between kinases.Kinase domain and best hit kinase group/family/subfamily are highlighted in red and blue. Visualized by pviz.
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| Domain | Protein name | Domain Name | Range | Identity (%) | Significance | Score | Profile Source | Profile Range (length) | Alignment |
|---|---|---|---|---|---|---|---|---|---|
| Kinase | MarkmB3.AA | MARK | 14-262 | 48 | 7.29999999999e-154 | 506.16 | In-house | 1-262 (262) | Show / Hide |
Range on Protein: 14-262 Range on HMM: 1-262/262 Sequence Identity: 48% (128 aa) YRVLSYLGEGAYGTVKLALHLKTEALVAIKMVE---ISQ-KTIDVILAELEVLKTLNHPNIIRLFQVLL--TSSH-VNFILEYASGGSLLDLIEEH--GP |..| ..|.|.|..||||.|..|. ||||..| .. ... . |.|..| |.|||||.||.| |..| ...|.||||||.|.| |..| |. YKMLKTIGHGSYAKVKLACHKHTGRKVAIKIYEKFKLNDPQWMKNVMREIEIMKKLDHPNIIKLFHVIEQDTEQHQIYLIMEYASGGELYDYIKAHPNGR LQEEEAKKIFGEILAAVKYCHNIDIIHGDIKPENILIDEKG--NMKLTDFGLAIKLSPGRLLSQRRGTKSFWAPELMLGEPYNGRKTDIWSLGVLLYFIT |.||||..|| |. ||.|||...|.| |||||||||||.| |.|..|||..|. ||..|. ||....|||..|..||.|.|.|||||||.|||.. LHEEEARRIFRQIVSAVNYCHSKNIVHRDIKPENILIDENGNHNIKIIDFGFSICIPPGQKLNTFCGTPPYMAPEIFLKKPYDGPKVDIWSLGVVLYFMV TGHYPFAGIT--FKEIKNKITTGSYRIPSYTSVKLENLIHQILTVTPEKRPSIEDIERHPWV .|..|| | | .||.. ||..|.|.||.. |....|||...||| ||.||.||.|..|||. CGYFPFDGDTQDYKELYKKILRGKYDIPCHVSKECRNLIQRLLTVNPEERPTIEEIMKHPWM |
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| Kinase | MarkmB3.AA | CAMKL | 14-262 | 36 | 6.8e-131 | 420.01 | In-house | 1-297 (297) | Show / Hide |
Range on Protein: 14-262 Range on HMM: 1-297/297 Sequence Identity: 36% (108 aa) YRVLSYLGEGAYGTVKLALH-LKTEALVAIKMVEISQKT-IDVILA---------------ELEVLKTLN---HPNIIRLFQVLLTSSH------VNFIL ||.. ||.|..|.||||.| . |. ||||..... .. ...... | . .| || |||||.|..|. |..| .. .. YRIGKTLGKGSFGKVKLATHIRTTGEKVAIKIIDKKKIWNDPWMKKNKCGQKHESDMRIRREIQIMKMLNIGKHPNIIKLYEVIETPEHDIETKKIYLVM EYASGGS--LLDLIEEH----GPLQEEEAKKIFGEILAAVKYCHNIDIIHGDIKPENILIDEKG--NMKLTDFGLAIKLSP-----GRLLSQRRGTKSFW ||.|||. |.| |..| |...|.||...| |..||.|||. .|.| ||||||||.||.| | |..|||.... | |..|. . |. ... EYCSGGEMDLFDYIVKHGHRRGRMPEHEARRYFRQIVSAVNYCHSHGIVHRDIKPENILLDENGNNNIKIIDFGFSNMYRPCIFGPGQKLKTFCGSPPYM APELMLG--EPYNGRKTDIWSLGVLLYFITTGHYPFAGITFK---------EIKNKITTGSYRIPSYTSVKLENLIHQILTVTPEKRPSIEDIERHPWV |||. .| .||.|.|.||||.||.||.. .|..|| . | . . |.... . ..|... | ...||...|.| |||||.|..|..|||. APEIFQGNNKPYDGPKVDIWSCGVILYAMVCGYLPFDDDTYNKQGKDNIYLYWKIMCG-YYPPIWYHVS-DCRDLIRKMLQVNPEKRPTIHQIMNHPWM |
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| Kinase | MarkmB3.AA | CAMK | 19-262 | 25 | 2.7e-110 | 356.71 | In-house | 1-425 (425) | Show / Hide |
Range on Protein: 19-262
Range on HMM: 1-425/425
Sequence Identity: 25% (109 aa)
YLGEGAYGTVKLALHLKTE------------ALVAIKMVEIS-----------------------------QKTIDVILAELEVLKT-------LNHPNI
||.|..|.|||. | .| ||||... . .|. . .. |.|..|. |.||||
TLGRGSFGKVKLCIHKNTTGKERVHHIYTNGQKVAIKIIDKKKLKDKQNQDYSNCYKIDKSKCKHRYCWRRPKDRKNVRREIEIMKKLQGIGNKLDHPNI
IRLFQVLL------------TSSH--------VNFIL---EYASGG----SLLDLIEEHGP---------------LQEEEAKKIFGEILAAVKYCHNID
|.|..| | |. . ... ||.||| |.| | |||. ..|.||...| |. ||.|||. .
IKLYEVYEDPHYFKNTNDYET-SKQVFTKDKHMYMVMEIMEYCSGGELFDDLFDYIVEHGCYGEEFDQFDIVERGRFTEREARRYFRQICSAVHYCHSHN
IIHGDIKPENILIDEK-----------------GNMKLTDFGLAIKLSP------------------------GRLLSQRRGTKSFWA-PELMLG-----
|.| |.||||||.|.. .| |..|||.|.|. | | ... . || .. | ||. .|
IVHRDLKPENILLDDNNDDSDPVEHDEIFDWNNNNIKIIDFGFANKFDPGENNFMCSDYKGGEMHNQWTTPTEGQKMKTFCGTPEYMAAPEVLNGKGHCN
--------EPYNGRKTDIWSLGVLLYFITTGHYPFAGI-------------TFKEIKNKITTGSYR-IPSYTSV-----------------------KLE
.|| |.|.|.||.||.||. .|..|| | . .|.. ||..| |. .|.| |
MQNATDEEKPYYGPKCDMWSCGVILYIMLCGYPPFYGDCDNEICEDEWIGMNDYELFEKIMKGKYDFPPPYFSPISCNYGPEWWDDISDEFHHFVSQECK
NLIHQILTVTPEKRPSIEDIERHPWV
.|| ..|.| ||||..||.. .|||.
DLIRKMLQVDPEKRMTIEQCLNHPWM
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| Kinase | MarkmB3.AA | NuaK | 14-262 | 39 | 2.4e-92 | 243.05 | In-house | 1-252 (252) | Show / Hide |
Range on Protein: 14-262 Range on HMM: 1-252/252 Sequence Identity: 39% (101 aa) YRVLSYLGEGAYGTVKLALHLKTEALVAIKMVE----ISQKTIDVILAELEVLKTLNHPNIIRLFQVLLTSSHVNFILEYASGGSLLDLIEEHGPLQEEE |... ||.| || |||| .| .|||| . ... . | | |.. .||||.|| . | .. . ..|||||| | | |.| . | |.| YEFQKTLGKGTYGKVKLATEHSTGREVAIKSIKKCKIEDEQDMVHIRREIEIMSSLNHPHIIHIYEVFENKDKIVIVMEYASGGELYDYISECKSLPERE AKKIFGEILAAVKYCHNIDIIHGDIKPENILIDEKGNMKLTDFGLAIKLSPGRLLSQRRGTKSFWAPELMLGEPYNGRKTDIWSLGVLLYFITTGHYPFA |...| | || ||| |.| | | |||| |...| | |||| . ...| | . || |.||.| | |||||||| . | || ARHFFRQIVSAVHYCHKHRICHRDLKLENILLDQNCNAKIADFGLSNYYHDQKFLHTFCGSPLYASPEIVNGQPYHGPEVDCWSLGVLLYTMVYGTMPFD GITFKEIKNKITTGSYRIPSYTSVKLENLIHQILTVTPEKRPSIEDIERHPWV | ||... |. | |. | |. . || ..|.| |..| .|.|| |.|| GHDFKHLVKQISQGAYYEPCKPSDACM-LIRWMLMVNPRRRATIYDICHHWWV |
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| Kinase | MarkmB3.AA | S_TKc | 14-262 | 33 | 2.6e-89 | 303.91 | SMART | 1-231 (231) | Show / Hide |
Range on Protein: 14-262 Range on HMM: 1-231/231 Sequence Identity: 33% (88 aa) YRVLSYLGEGAYGTVKLALHLKTEALVAIKMVEISQKTIDVILAELEVLKTLNHPNIIRLFQVLLTSSHVNFILEYASG--GSLLDLIEEHGP------L |..| .|.||.|.|... | || .||||.. . |. |...|| .||||..|. | . .|. ...||..| |.|.|.|...|. . YEILRKIGKGAFGKVYKCRHKKTGRIVAIKIIK------EHIRREIQILKK-HHPNIVKLYDVFQD-DHLYMVMEYCDGDLGDLFDYIKKRGRHGLRFPF QEEEAKKIFGEILAAVKYCHNIDIIHGDIKPENILIDEKGNMKLTDFGLAIKLSPGRLLSQRRGTKSFWAPELMLGEPYNGRKTDIWSLGVLLYFITTGH | .|.... .|. |..|||. ||| |.||||||.|| . |..||||| .| . || . |||.. .|...| |.||.|..|| .| PE-HARFYMYQICCALEYCHSHGIIHRDLKPENILLDE--HIKICDFGLARQL------TTFCGTPWYMAPEVL---GYGKCKCDWWSCGCILYEMLCGY YPFAGITFKEIKNKITTGSYRIPSYTSVKLENLIHQILTVTPEKRPSIEDIER-------HPWV || . ... .|| | . ..| ..|.. |||||.. .. . |||. PPFP--QMQMMFKKIG----------SPEAKDFIRKCLQKDPEKRPTA-EALQDEWDIKCHPWF |
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| Kinase | MarkmB3.AA | Pkinase | 14-262 | 29 | 4.1e-85 | 293.86 | Pfam | 1-293 (293) | Show / Hide |
Range on Protein: 14-262 Range on HMM: 1-293/293 Sequence Identity: 29% (88 aa) YRVLSYLGEGAYGTVKLALHLKTEALVAIKMVEISQKTIDV---ILA--ELEVLKTLNHPNIIRLFQVLLTSSHVNFILEYASGG----SLLDLIE--EH |.... .|.|..|.|... | .|. .||.| .. . . .. . |....| ||||||.||. . ...|. ...||. || .| |.|. .| YHIGRKIGSGSFGCVYKCHHKGTGKIVAVKIIKKRHEKSWKDQTHRRLSEIQIMKRLNHPNIVRLYDWFEDKDHIYMVMEYCEGGLYVMDLFDYISTWRH GPL--QEEEAKKIFGEILAAVKYCHNIDIIHGDIKPENILIDEKGNM----KLTDFGLAIK--LSPGRLLSQRRGTKSFWAPELMLGEPYNGRKTDIWSL |.. .|.|.|... .|| ...|||. ||| |.||||||||..|. |..||||| . . ... .. . || . |||. .| .| |.| |.||. GCFYFSEWECKFYMYQILRGLEYCHSMGIIHRDLKPENILIDNNGHIDACVKICDFGLAKQFDY-NNS-MTTFCGTPWYMAPEVIRGGQYYGPKVDMWSC GVLLYFITTGHYPFAGI------TFKEIKNKITTGSYRIPSYTS---------------------VKLENLIHQILTVTPEKRPSIEDIERHPWV |..|| .|. || | . ... ..| . .. ..... . .| .|.. |.|||..|.| |||. GCILYEMLCGRPPFPGHCWHDNHDQMQMICRIMGPPLHFDWPWWCSISYFFFRHWHFHWTFHNWSEECKDFIKWCLCKDPKKRPTAEQILQHPWF |
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| Kinase | MarkmB3.AA | AMPK | 14-262 | 39 | 2e-84 | 250.57 | In-house | 1-254 (254) | Show / Hide |
Range on Protein: 14-262
Range on HMM: 1-254/254
Sequence Identity: 39% (101 aa)
YRVLSYLGEGAYGTVKLALHLKTEALVAIKMVE----ISQKTIDVILAELEVLKTLNHPNIIRLFQVL-LTSSHVNFILEYASGGSLLDLIEEHGPLQEE
| . .|||..| ||.. | | |||| . ..|.. | |.. || ..||.||.|..|. | . ..||.||| | | | || |||.
YIIGKTIGEGTFGKVKMGTHILTGEKVAIKILNKQKIKDQDMVERIQREIHILKLFRHPHIIQLYEVIIETPTDIFMVMEYVSGGELFDYIVKHGRLQER
EAKKIFGEILAAVKYCHNIDIIHGDIKPENILIDEKGNMKLTDFGLAIKLSPGRLLSQRRGTKSFWAPELMLGEPYNGRKTDIWSLGVLLYFITTGHYPF
||.. | |...| |||.. | | | ||||.|.|.. | |. |||| . | .|. | |||. | .|.|...|||| || || | ||
EACRFFQQIISGVEYCHRHMIVHRDLKPENLLLDHNKNIKIVDFGLSNMMKDGEFLKTACGSPCYAAPEMISGKLYCGPEVDIWSCGVILYAMLCGYLPF
AGITFKEIKNKITTGSYRIPSYTSVKLENLIHQILTVTPEKRPSIEDIERHPWV
. ||. | | ||.. | . ..||...|.| |.|| .|.|| |||
DDENTPTLYKKIKNGEYYIPKFLSPEAKDLIKHMLQVDPMKRITIHDIRNHPWF
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| Kinase | MarkmB3.AA | QIK | 14-262 | 36 | 7.7e-81 | 274.87 | In-house | 1-272 (272) | Show / Hide |
Range on Protein: 14-262
Range on HMM: 1-272/272
Sequence Identity: 36% (98 aa)
YRVLSYLGEGAYGTVKLALHLKTEALVAIKMVEISQ---KTIDVILAELEVLKTLNHPNIIRLFQVLLTSSHVNFILEYASGGSLLDLIEEHGP------
| . .| | ...|||| | | . |||| . || . . . | ...| |.||.||.|.||. | . . ||.|.| . | . .||
YDIERTIGKGNFAVVKLARHRITKTKVAIKIIDKSQLDEENLQKCYREVQIMKMLYHPHIIKLYQVMETDDMMYIVTEYCSNGEMFDYLCKHGRKGVKMV
--------------LQEEEAKKIFGEILAAVKYCHNIDIIHGDIKPENILIDEKGNMKLTDFGLAIKLSPGRLLSQRRGTKSFWAPELMLGEPYNGRKTD
..|.||...| .|..||.|||. |.| |.| ||||.|. | |. |||. .| ||. |. . |||...|. |.| | |
NSPDIGDQVLMGVPMAENEARRWFWQICSAVHYCHKRNIVHRDLKAENILLDNNMNIKIADFGFSNWFKQGQLLMTWCGSPPYAAPEMFEGKEYDGPKVD
IWSLGVLLYFITTGHYPFAGITFKEIKNKITTGSYRIPSYTSVKLENLIHQILTVTPEKRPSIEDIERHPWV
|||.||.|| .| || | | .. .... | .||| . |. .| || . |.| ||.| .|. | .|.|
IWSMGVVLYVLVCGALPFDGKTLQNLRQRVLSGKFRIPFFMSQDCEHLIRHMLVVDPEHRYTIMQICQHRWM
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| Kinase | MarkmB3.AA | Ciliate-E2 | 14-262 | 23 | 9.8e-69 | 234.66 | In-house | 1-365 (365) | Show / Hide |
Range on Protein: 14-262
Range on HMM: 1-365/365
Sequence Identity: 23% (89 aa)
YRVLSYLGEGAYGTVKLALHLKTEA-----------------------LVAIKMVE----ISQKTIDVIL----------AELEVLKTLNHPNIIRLFQV
| .. .|.|..|.|... . |. ..|.|... ...| .. |. |...|..|||||||... .
YKFIKKIGQGNFGSVYKCKVWKVQKQFAIKIIDQKQQRQQMQEKVKIKIYAMKIMKKNQIEQIKQEIHIMREINCFYKKINEKNILEQLNHPNIIKMYEC
LL--TSSHVNFILEYASGGSLLDLIEEH-----------GPLQEEEAKKIFGEILA---------------AVKYCHNID-IIHGDIKPENILIDEKGNM
. ... ...||..||.|.|.|... ... |.|.|.|. .|| |..|.|. ||| ||||||||.
FQEKDDNNIYLVMEYCQGGDLFDYIKNNKKKRNHEIEKDKYFTEKEIKYIMKQILQGFKTKAEFYIACIILALEYLHSKNNIIHRDIKPENILF-----I
KLTDFGLAIKLSPG----------RLLSQRR-----------------------GTKSFWAPELMLGEPYNG--------RKTDIWSLGVLLYFITTGHY
|..||||. |... .. . . || . ||| |..|.. | |||||||.||. .| .
KIIDFGLSKKYDDDNQNRTHKQQCKWYMF-KNDTSRTPGYMDQIIQQNMFNTICGTPGYMAPEILNGKKYDNQQKQKGYDYKCDIWSLGVILYEMLFGKP
PFAGITFKEIKN-KITTGSYR-------------IPSYTSVKLENLIHQ----ILTVTPEKRPS-IEDIERHPWV
|| ...||. || .. .. . | . .|| . .| . ||||.. .|.| |||
PF----QQQIKQCKIDFPCPEWQKDTQCIQCKWKSWKKWSQECKDLIKKFGKRMLQKDPEKRITGWEQILNHPWF
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| Kinase | MarkmB3.AA | Ciliate-E2-Unclassified | 14-262 | 23 | 4.2e-66 | 225.93 | In-house | 1-352 (352) | Show / Hide |
Range on Protein: 14-262
Range on HMM: 1-352/352
Sequence Identity: 23% (83 aa)
YRVLSYLGEGAYGTVKLALHLKTEALV-----AIKMVEISQKTI---DVILAELEVLKTLN-------------------HPNIIRLFQVLLTSSHVNFI
|... .|.|..|.|... | |. .. ..|. ...|| | | |. |.. .. .. ||.|...| . . .. ..
YKIIKQIGQGGFGKVYKCQHKKQK-QYYAMKYMKKIQIYKQKQIMNKDEIMNEMKEMNNKKKYHQRKYNKIMQQILLNHPHPFIVKMFYCFQDKQNIYIV
LEYASGGSLLDLIEEHGP-----------------LQEEEAK-----KIFGEILAAVKYCHNID-IIHGDIKPENILIDEKG---NMKLTDFGLAIKLS-
.||. ||.|.. |.. . ..|..|| ..| .|| . .|.| ||| ||||||||.|..| . |..|||...|.
MEYCEGGDLWQYIKKRKKQKQKGNDLFHNMKQRKIFTEQQAKYKKAKFYFAQILQGLEYLHHKNNIIHRDIKPENILFDNNGKNYYIKIIDFGISKKYQQ
---------------PGRLLSQRRGTKSFW----APELMLGEPYNGR---KTDIWSLGVLLYFITTGHYPFAGITFKE----------------IKNKIT
. ..... || .. |||.. |. |... | |||||||.||.. .| ||| . . .. ....|
NNNCDTNQQQKMQIWKQQMMWTFCGTPNYMPQYTAPEVLQGQNYDHSKAYKCDIWSLGVILYEMLFGYYPFYDNNCEQHQQLITQWINNAYRKQLYQNIK
TGSYRIPSYTS----VKLE--------NLIHQILTVTPEKRPSIEDIERHPWV
. . .|.. .. .|....| . |.||...|.| |||
QKNIQFPKFPWQQIPKHWSPEAKDFINDLLQKMLKKNPNKRITFEQILNHPWF
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| Kinase | MarkmB3.AA | MELK | 14-262 | 36 | 8.3e-64 | 216.86 | In-house | 1-254 (254) | Show / Hide |
Range on Protein: 14-262 Range on HMM: 1-254/254 Sequence Identity: 36% (92 aa) YRVLSYLGEGAYGTVKLALHLKTEALVAIKMVEISQKTIDV--ILAELEVLKTLNHPNIIRLFQVLLTSSHVNFILEYASGGSLLDLIEEHGPLQEEEAK | | .| | .. |||| |. |. ||||... | |. . .|.. || | | .| .|. .. | . ..|| .|| ..| | .. |.|||.. YEVHDEIGTGGFAKVKLACHILTNQMVAIKIMDKNQLGHDLPRVKTEMDALKNLRHQHICQLYHYIETEDKIFMVMEYCPGGEMFDYIIRQDRLEEEETR KIFGEILAAVKYCHNIDIIHGDIKPENILIDEKGNMKLTDFGLAIKLSPGRLLSQ----RRGTKSFWAPELMLGEPYNGRKTDIWSLGVLLYFITTGHYP ..| .|..|. | | | |.||||.|.||. ..|| |||| | || | . ||||. | | | |.||.|.||| . | | HFFRQIVSAIAYVHSQGYAHRDLKPENLLFDEDHHLKLIDFGLCAKT-KGRKDYHNLQTCCGSPAYAAPELIQGKQYIGSEADVWSMGILLYVLMCGFLP FAGITFKEIKNKITTGSYRIPSYTSVKLENLIHQILTVTPEKRPSIEDIERHPWV | . . || | | | . |.. .|....| | |.|| |. .. |||| FDDDNMMIMYKKIMSGCYEEPKWLSPESKQLLRHMLQVDPKKRISMKNLLNHPWV |
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| Kinase | MarkmB3.AA | ULK | 14-262 | 26 | 1.1e-63 | 217.86 | In-house | 1-329 (329) | Show / Hide |
Range on Protein: 14-262 Range on HMM: 1-329/329 Sequence Identity: 26% (86 aa) YRVLSYLGEGAYGTVKLALHLKTE----ALVAIKMVE---ISQKT--------IDVILAELEVLKTLN--------HPNIIRLFQVLLTS--SHVNFILE | . ||.|..|.| . . ||. .||.||.. ..|| .. . | ...|.|. ||||..|. .. || .. .|.| YCLNHCLGKGSFGKVYKGRNKKTKDYVNEKVACKMIDKQKMNQKNNEQEGQYMWQLLKNEIKIMKKLKSPNRHKNHHPNIVKLYDWFETSNHNNIYIIME YASGGSLLDLIEEHGP----------LQEEEAKKIFGEILAAVKYCHNIDIIHGDIKPENILIDEK------------GNMKLTDFGLAIKLSPG----R | || | ..|..... | |.||...| ||.. |. | ||| ||||.||||... | |..|||.| ... . . YCNGGDLEQYIKKNKKLPEDTEEKKRLSEQEAIQFFKQILNGFKELHKHNIIHRDIKPQNILIHNGQPKTDSKKVHPNGVLKIADFGFAKHVDNDNMEQQ LLSQRR------GTKSFWAPELML----GEPYNGRKTDIWSLGVLLYFITTGHYPFAGITFKEIK-----NKITTG--------SYRIPSY-------TS .. || . ||.. ..||. |.||||||...| . .| .|| . | . . . | . . . . | MMMTCVNEKRLCGTPLYMAPQILQGQGEQKPYYDYKCDIWSLGCIFYEMLYGKPPFYAW-FNDQYLQIIQKLINNPPPWPQQIKKQPLQFPKDGNDPQIS VKLENLIHQILTVTPEKRPSIEDIERHPWV ....|| . |.. ...| |.|.. |||. PECKDLIRRMLQYDEKDRISWEELFNHPWF |
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| Kinase | MarkmB3.AA | TyrKc | 14-262 | 23 | 1.5e-22 | 82.15 | SMART | 1-280 (280) | Show / Hide |
Range on Protein: 14-262 Range on HMM: 1-280/280 Sequence Identity: 23% (69 aa) YRVLSYLGEGAYGTVKLALHLKTEALVAIKMVEISQKTIDVILAELEVLKTL--NHPNIIRLFQVLLTS-------SHVNFILEYASGGSLLDLIEEHGP . . |||||.|.| .. ||.||. . . .. |..... | .||||.||. | ... . ..||...|.|.| . .|.| ITLGKKLGEGAFGEVYKGTWK---IQVAVKMLKEDA--REDFMREARIMCKLGGHHPNIVRLYGVCTQQGRNFMYIEPLMIVMEYMPHGDLKDYLRKHRP -LQEEEAKKIFGEILAAVKYCHNIDIIHGDIKPENILIDEKGNMKLTDFGLAIKLSPG-------RLLSQRR--GTKS----FW-APELMLGEPYNGR-- |. .. .. | . | | .|| |. |.|..|.. .| .||||. .. . ... |.|. | ||| . | . KLCMKDLLSFCWQIACGMEYLHSKNCIHRDLAARNCLVGENHTVKISDFGLSRDIYDDDQQGESKDYYRKKEHKGGKTMLPIRWMAPECI-----NYGKF --KTDIWSLGVLLY-FITTGHYPFAG-----ITFKEIKNKITTG-SYRIPSY--------TSVKLENLIHQILTVTPEKRPSIEDIERHPWV |.|.|| ||... | | | | .. .|. ... .| ..| . . .. ... | ||.||. ..| | TTKSDVWSFGVCMWEIFTYGQQPYPGMIQQMMSNQEVIEYVKQGYRMPQPPNDYPMSFVCCPDEMYQIMKQCWHEDPEDRPTFSEI--HECF |
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| Kinase | MarkmB3.AA | Pkinase_Tyr | 14-158 | 27 | 4e-18 | 62.0 | Pfam | 1-161 (270) | Show / Hide |
Range on Protein: 14-158 Range on HMM: 1-161/270 Sequence Identity: 27% (45 aa) YRVLSYLGEGAYGTVKLALHL----KTEALVAIKMV--EISQKT--IDVILAELEVLKTL-NHPNIIRLFQVLL-TSSH--VNFILEYASGGSLLDLIEE . . |||||.|.|... .|. ||.||. ... .. ..|....|.| .||||.|| | . . . . ..||. .|.||| . ITFGKKLGEGAFGEVYKGTWKGDPDNTKIPVAVKMLKEGAMHEQNCREDFMREAKIMKQLGHHPNIVRLYGVCTDQGEPNQIYIVMEYMPHGDLLDYLRK H----GPLQEEEAKKIFGEILAAVKYCHNIDIIHGDIKPENILIDEKGNMKLTDFGLAIKL | .|| .. .. .| .. | ... .|| |. |.|..|.. .| .||||| . HREDKQPLTMKDLLQMCWQIAKGMEYLESKNCIHRDLAARNCLVTENNVVKICDFGLARDI |
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| Kinase | MarkmB3.AA | Pkinase_Tyr | 188-228 | 39 | 0.137705 | 6.0 | Pfam | 194-236 (270) | Show / Hide |
Range on Protein: 188-228 Range on HMM: 194-236/270 Sequence Identity: 39% (17 aa) KTDIWSLGVLLYFITT-GHYP-FAGITFKEIKNKITTGSYRIP |.|.|| |||.. | | | | ..|.. |....|. || | KSDVWSFGVLMWEIFTYGEQPTYPGMSNEEVYEYIYEDGYRMP |
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| UBA_CAMKL | MarkmB3.AA | UBA_CAMKL | 276-313 | 41 | 2.9e-12 | 42.17 | In-house | 1-41 (41) | Show / Hide |
Range on Protein: 276-313 Range on HMM: 1-41/41 Sequence Identity: 41% (17 aa) DYTIIDMLCGM--GFDANKILESLQKKKF-DENMGTYLLLK | ||. .| | ||| ..| |||.. |. .. ..||.|| DEEIIQEMCKMWHGFDREEIIESLRNNKYHNHITATYYLLL |
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| UBA | MarkmB3.AA | UBA | 276-313 | 26 | 2e-06 | 28.67 | SMART | 1-38 (38) | Show / Hide |
Range on Protein: 276-313 Range on HMM: 1-38/38 Sequence Identity: 26% (10 aa) DYTIIDMLCGMGFDANKILESLQKKKFDENMGTYLLLK . ..||.|..|||| . ....|.. . ...| ...|. YEEKIDQLMEMGFDREECVQALRACNWNVEMAMNWLFS |
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