PIM1

Species: Mouse
Alias: Pim1, PIM1
External Links: MGI , Entrez Gene , Refseq cDNA , Refseq Protein , Phosphosite , iHOP
Annotation:

Classification

Group: CAMK
Family: PIM

Sequence

Name Sequence Type Origin Length Description Download
PIM1.kin_dom Protein Kinase Domain Sugen global kinase HMM prediction 253 Kinase domain by global Sugen HMM Fasta, JSON
PIM1.AA Protein Sugen 397 None Fasta, JSON
PIM1.NA RNA Sugen 2032 None Fasta, JSON

Protein domain

Protein domains of PIM1.AA. The domains are annotated by HMM profiles from Pfam and SMART, as well as in-house data which includes HMMs of each individual kinase group, family and subfamily. Here is domain list in details, including sequence identity, significance and alignment. In particular, you can find can find the best hit kinase group/family/subfamily, which is helpful to understand the relationship between kinases.Kinase domain and best hit kinase group/family/subfamily are highlighted in red and blue. Visualized by pviz.

Usage: Zoom in selected region by dragging mouse and zoom out by double-clicking.

Domain Protein name Domain Name Range Identity (%) Significance Score Profile Source Profile Range (length) Alignment
Kinase PIM1.AA PIM 122-374 68 5e-208 697.37 In-house 1-260 (260) Show / Hide
Range on Protein: 122-374
Range on HMM: 1-260/260
Sequence Identity: 68% (179 aa)

YQVGPLLGSGGFGSVYSGIRVADN-LPVAIKHVEKDRISDWGELPNGTRVPMEVVLLKKVSSD--FSGVIRLLDWFERPDSFVLILERPEPVQDLFDFIT
|||||.||.||||.||.|.|..|| .|||||||||.|..|||.|..|..|||||..|.|.||   ..|||||||||||||.|....|||.|.||||||||
YQVGPELGRGGFGTVYAGHRICDNQQPVAIKHVEKERVKDWGMLCDGQQVPMEVCMLWKCSSIGGHHGVIRLLDWFERPDGFMIVMERPYPCQDLFDFIT

ERGALQEDLARGFFWQVLEAVRHCHNCGVLHRDIKDENILIDLSRGEIKLIDFGSGALLKDTVYTDFDGTRVYSPPEWIRYHRYHGRSAAVWSLGILLYD
|.|.|.||..| |||||...|.|||.|.||||||||||||||...||.||||||.||.|.|||||||||||||.||||||.||||||.|.|||||.||||
EQGPLNEDMCRFFFWQVWATVHHCHQCHVLHRDIKDENILIDMNTGEVKLIDFGAGAMLHDTVYTDFDGTRVYCPPEWIRHHRYHGREATVWSLGVLLYD

MVCGDIPFEHDEEIIK----GQVFFRQTVSSECQHLIKWCLSLRPSDRPSFEEIRNHPWM
|||||||||.|.||..    |...|||.||.||..||.|||...||.|.|.|.|.|||||
MVCGDIPFENDQEICRAHLLGELHFRQHVSHECCQLIRWCLTFKPSHRCSLEQILNHPWM

Kinase PIM1.AA CAMK 127-374 21 3.5e-92 297.28 In-house 1-425 (425) Show / Hide
Range on Protein: 127-374
Range on HMM: 1-425/425
Sequence Identity: 21% (92 aa)

LLGSGGFGSVYSGIRVADN------------LPVAIKHVEKDRISD----------------------WGELPNGTRVPMEVVLLKKVSS-----DFSGV
 ||.|.|| |. .|.  ..              |||| ..|....|                      | .  .  .|. |. ..||...     |   .
TLGRGSFGKVKLCIHKNTTGKERVHHIYTNGQKVAIKIIDKKKLKDKQNQDYSNCYKIDKSKCKHRYCWRRPKDRKNVRREIEIMKKLQGIGNKLDHPNI

IRLLDWFE--------RPDS------------FVLIL---ERPEPV---QDLFDFITER---------------GALQEDLARGFFWQVLEAVRHCHNCG
|.|....|        .. .            .....   |  .     .||||.|.|.               | ..|. || .|.|...||..||...
IKLYEVYEDPHYFKNTND-YETSKQVFTKDKHMYMVMEIMEYCSGGELFDDLFDYIVEHGCYGEEFDQFDIVERGRFTEREARRYFRQICSAVHYCHSHN

VLHRDIKDENILIDLSR----------------GEIKLIDFGSGALLKDTV-------------------------YTDFDGTRVYSP-PEWIRY-----
. |||.| ||||.| .                 . ||.||||  . ...                           ...| ||  | . ||....     
IVHRDLKPENILLDDNNDDSDPVEHDEIFDWNNNNIKIIDFGFANKFDPGENNFMCSDYKGGEMHNQWTTPTEGQKMKTFCGTPEYMAAPEVLNGKGHCN

--------HRYHGRSAAVWSLGILLYDMVCGDIPFEHD-------------------EEIIKGQVFFRQT----------------VSSE--------CQ
        ..|.|... .||.|..|| |.||  ||..|                   | |.||.  |                   .| |        |.
MQNATDEEKPYYGPKCDMWSCGVILYIMLCGYPPFYGDCDNEICEDEWIGMNDYELFEKIMKGKYDFPPPYFSPISCNYGPEWWDDISDEFHHFVSQECK

HLIKWCLSLRPSDRPSFEEIRNHPWM
.||...|   |..|.. |.. |||||
DLIRKMLQVDPEKRMTIEQCLNHPWM

Kinase PIM1.AA Pkinase 122-374 29 5.5e-92 316.7 Pfam 1-293 (293) Show / Hide
Range on Protein: 122-374
Range on HMM: 1-293/293
Sequence Identity: 29% (91 aa)

YQVGPLLGSGGFGSVYSGIRVADNLPVAIKHVEKDRISDWGE-----LPNGTRVPMEVVLLKKVSSDFSGVIRLLDWFERPDSFVLILERPEP---VQDL
|..|  .|||.||.|| .... ..  ||.| ..|.....| .     |       .|. ..|......  ..||.||||..|.  ...|  |    |.||
YHIGRKIGSGSFGCVYKCHHKGTGKIVAVKIIKKRHEKSWKDQTHRRL-------SEIQIMKRLNHPN--IVRLYDWFEDKDHIYMVMEYCEGGLYVMDL

FDFIT--ERGAL--QEDLARGFFWQVLEAVRHCHNCGVLHRDIKDENILIDLSRGEI----KLIDFGSGA---LLKDTVYTDFDGTRVYSPPEWIRYHRY
||.|.  ..|..  .|. .. ...|.|... .||..|..|||.| |||||| ..|.|    |..|||. .   . ... .|.| ||. | .||.|| ..|
FDYISTWRHGCFYFSEWECKFYMYQILRGLEYCHSMGIIHRDLKPENILID-NNGHIDACVKICDFGLAKQFDY-NNS-MTTFCGTPWYMAPEVIRGGQY

HGRSAAVWSLGILLYDMVCGDIPFEHD---EEIIKGQVFFRQTVS-------------------------------SECQHLIKWCLSLRPSDRPSFEEI
.|... .||.|..|| |.||  || ..   .. .  .. .... .                               .||...||||| . |..||..|.|
YGPKVDMWSCGCILYEMLCGRPPFPGHCWHDN-HDQMQMICRIMGPPLHFDWPWWCSISYFFFRHWHFHWTFHNWSEECKDFIKWCLCKDPKKRPTAEQI

RNHPWM
 .|||.
LQHPWF

Kinase PIM1.AA CAMKL 122-374 30 3.3e-72 229.69 In-house 1-297 (297) Show / Hide
Range on Protein: 122-374
Range on HMM: 1-297/297
Sequence Identity: 30% (91 aa)

YQVGPLLGSGGFGSVYSGIR-VADNLPVAIKHVEKDRIS--DWGE--------LPNGTRVPMEVVLLKKVSSD-FSGVIRLLDWFERPDS------FVLI
|..|. || |.|| |  ..     .  |||| ..|..|.  .| .        . .  |.  |. ..|....     .|.|.. .| |.       ..|.
YRIGKTLGKGSFGKVKLATHIRTTGEKVAIKIIDKKKIWNDPWMKKNKCGQKHESDM-RIRREIQIMKMLNIGKHPNIIKLYEVIETPEHDIETKKIYLV

LERPEPVQ-DLFDFITERGA----LQEDLARGFFWQVLEAVRHCHNCGVLHRDIKDENILIDLSRG-EIKLIDFGSGALLK------DTVYTDFDGTRVY
.|  .    ||||.| ..|     ..|. || .|.|...|| .||..|. ||||| ||||.| .    ||.|||| ... .      .   . | |.  |
MEYCSGGEMDLFDYIVKHGHRRGRMPEHEARRYFRQIVSAVNYCHSHGIVHRDIKPENILLDENGNNNIKIIDFGFSNMYRPCIFGPGQKLKTFCGSPPY

SPPEWIRY-HR-YHGRSAAVWSLGILLYDMVCGDIPFEHD------------EEIIKGQVFFRQ---TVSSECQHLIKWCLSLRPSDRPSFEEIRNHPWM
 .|| .   .. |.|. . .||.|..|| ||||  ||. |            ...|... ..      || .|..||.. |   |..||. ..|.|||||
MAPEIFQGNNKPYDGPKVDIWSCGVILYAMVCGYLPFDDDTYNKQGKDNIYLYWKIMCG-YYPPIWYHVS-DCRDLIRKMLQVNPEKRPTIHQIMNHPWM





Kinase PIM1.AA S_TKc 122-374 29 1.1e-71 245.33 SMART 1-231 (231) Show / Hide
Range on Protein: 122-374
Range on HMM: 1-231/231
Sequence Identity: 29% (80 aa)

YQVGPLLGSGGFGSVYSGIRVADNLPVAIKHVEKDRISDWGELPNGTRVPMEVVLLKKVSSDFSGVIRLLDWFERPDSFVLILERPEP-VQDLFDFITER
|... ..|.|.||.|| .. . ..  |||| .               ..  |. .|||   .   ...|.|.|.  |.. ...|  .  . ||||.| .|
YEILRKIGKGAFGKVYKCRHKKTGRIVAIKIIK-------------EHIRREIQILKK---HHPNIVKLYDVFQD-DHLYMVMEYCDGDLGDLFDYIKKR

GA------LQEDLARGFFWQVLEAVRHCHNCGVLHRDIKDENILIDLSRGEIKLIDFGSGALLKDTVYTDFDGTRVYSPPEWIRYHRYHGR-SAAVWSLG
|       . |  || ...|...|. .||. |..|||.| ||||.|    .||..|||. ..|     | | ||. | .|| .     .|. .. .||.|
GRHGLRFPFPE-HARFYMYQICCALEYCHSHGIIHRDLKPENILLDE---HIKICDFGLARQL-----TTFCGTPWYMAPEVL----GYGKCKCDWWSCG

ILLYDMVCGDIPFEHDEEIIKGQVFFRQTVSSECQHLIKWCLSLRPSDRPSFEEIRN-------HPWM
..|| |.||  ||. ... .  ..      |.|. ..|. ||   |..||.  |. .       |||.
CILYEMLCGYPPFP-QMQMMFKKIG-----SPEAKDFIRKCLQKDPEKRPTA-EALQDEWDIKCHPWF

Kinase PIM1.AA PASK 122-374 32 3.3e-58 180.36 In-house 1-260 (260) Show / Hide
Range on Protein: 122-374
Range on HMM: 1-260/260
Sequence Identity: 32% (85 aa)

YQVGPLLGSGGFGSVYSGIRVADNLPVAIKHVEKDRISD--WGELPNGTRVPMEVVLLKKVS-SDFSGVIRLLDWFERPDSFVLILERPEPV--QDLFDF
|     .|.| .| |.  |.  ... | .| . | ..    | . .   ..|.|. .. ..       ....|| ||  | . |  |        |||||
YTSIQQMGEGAYGYVWMCIHNECRYIVVVKFIFKEKVCEDCWVRDRKCGCIPLEIHIMQTLNKNPHENIVKVLDFFENDDFYQLVMEKHGSGGCMDLFDF

ITERGALQEDLARGFFWQVLEAVRHCHNCGVLHRDIKDENILIDLSRGEIKLIDFGSGALLKDTV-YTDFDGTRVYSPPEWIRYHRYHGRSAAVWSLGIL
|  .  . | ||   | ||  || . |  |..||||||||. || . . |||||||| | ..    .  | ||  |  ||     .| |.   .|.||..
IDRHPNMDEHLASYIFRQVVAAVKYLHEQGIVHRDIKDENVIID-EHFTIKLIDFGSAAYMERGKFFYTFCGTIEYCAPEVLMGNPYRGPEQEMWALGVT

LYDMVCGDIPFEHDEEIIKGQVFFR--QTVSSECQHLIKWCLSLRPSDRPSFEEIRNHPWM
|| ..    ||   ||...... |   . || ||  |||  |   |  |.  ..| . ||.
LYTLMFKENPFCNIEETLEAEIHFPNAEHVSEECMSLIKSMLNRCPEKRCTMHQIITDPWL

Kinase PIM1.AA MARK 122-374 34 7.3e-55 177.85 In-house 1-262 (262) Show / Hide
Range on Protein: 122-374
Range on HMM: 1-262/262
Sequence Identity: 34% (94 aa)

YQVGPLLGSGGFGSVYSGIRVADNLPVAIKHVEKDRISDWGELPNGTRVPMEVVLLKKVSSDFSGVIRLLDWFE--RPDS-FVLILERPEPVQDLFDFIT
| ..  .| |... |. .. .  .  |||| .|| ...|  .. |  |   |. ..||.  |.  .|.|.. .|   .   ..||.|  .  ..|.|.| 
YKMLKTIGHGSYAKVKLACHKHTGRKVAIKIYEKFKLNDPQWMKNVMR---EIEIMKKL--DHPNIIKLFHVIEQDTEQHQIYLIMEYAS-GGELYDYIK

ER--GALQEDLARGFFWQVLEAVRHCHNCGVLHRDIKDENILIDLSRG--EIKLIDFGSGALL-KDTVYTDFDGTRVYSPPEWIRYHRYHGRSAAVWSLG
..  | |.|..|| .| |...||  ||. .. ||||| |||||| ..|   ||.|||| ..    ..  . | ||  | .|| . . .| |. . .||||
AHPNGRLHEEEARRIFRQIVSAVNYCHSKNIVHRDIKPENILID-ENGNHNIKIIDFGFSICIPPGQKLNTFCGTPPYMAPEIFLKKPYDGPKVDIWSLG

ILLYDMVCGDIPFE--H--DEEI----IKGQVFFRQTVSSECQHLIKWCLSLRPSDRPSFEEIRNHPWM
..|| ||||  ||.     ..|.     .|.  .   || ||..||.. | . |..||. ||| .||||
VVLYFMVCGYFPFDGDTQDYKELYKKILRGKYDIPCHVSKECRNLIQRLLTVNPEERPTIEEIMKHPWM

Kinase PIM1.AA Ciliate-E2 122-374 20 6.2e-46 155.66 In-house 1-365 (365) Show / Hide
Range on Protein: 122-374
Range on HMM: 1-365/365
Sequence Identity: 20% (76 aa)

YQVGPLLGSGGFGSVYSG--IRV---------------------ADNLPVAIKHVEKDRISDWGELPNGT--------RVPMEVVLLKKVSSDFSGVIRL
| .  ..|.|.||||| .  ..|                     ...  .|.| ..|. |  .    .          .  .|  .|.......  .|..
YKFIKKIGQGNFGSVYKCKVWKVQKQFAIKIIDQKQQRQQMQEKVKIKIYAMKIMKKNQIEQIKQEIHIMREINCFYKKI-NEKNILEQLNHPN--IIKM

LDWFE--RPDSFVLILERPEPVQDLFDFITER-----------GALQEDLARGFFWQVLE---------------AVRHCHNCG-VLHRDIKDENILIDL
 ..|.    ... |..|  .  .||||.| ..           . . |  .. ...|.|.               |....|. . ..||||| ||||.  
YECFQEKDDNNIYLVMEYCQ-GGDLFDYIKNNKKKRNHEIEKDKYFTEKEIKYIMKQILQGFKTKAEFYIACIILALEYLHSKNNIIHRDIKPENILF--

SRGEIKLIDFGSGA---------------------------------LLKDTVYTDFDGTRVYSPPEWIRY--------HRYHGRSAAVWSLGILLYDMV
    ||.||||                                     ... ..  . ||  | .|| ...        . ... .. .||||..|| |.
----IKIIDFGLSKKYDDDNQNRTHKQQCKWYMFKNDTSRTPGYMDQIIQQNMFNTICGTPGYMAPEILNGKKYDNQQKQKGYDYKCDIWSLGVILYEML

CGDIPFEHDEEIIKGQVFFR------------------QTVSSECQHLIKW----CLSLRPSDRPS-FEEIRNHPWM
.|  ||   ..|..... |.                  . .| ||..|||     .|   |. |.. .|.| ||||.
FGKPPF--QQQIKQCKIDFPCPEWQKDTQCIQCKWKSWKKWSQECKDLIKKFGKRMLQKDPEKRITGWEQILNHPWF

Kinase PIM1.AA Ciliate-E2-Unclassified 122-374 22 2.9e-42 144.4 In-house 1-352 (352) Show / Hide
Range on Protein: 122-374
Range on HMM: 1-352/352
Sequence Identity: 22% (78 aa)

YQVGPLLGSGGFGSVYSGIRVADNLPVAIKHVEKDRISDWGELPNGTRVPMEV---VLLKK---------------VSSDFSGVIRLLDWFERPDSFVLI
| ..  .|.||||.||  ..  ...  |.|   | .| .     |     |     .  ||               ....   .......|.  . . ..
YKIIKQIGQGGFGKVYKCQHKKQKQYYAMKYMKKIQIYKQKQIMNKD-EIMNEMKEMNNKKKYHQRKYNKIMQQILLNHPHPFIVKMFYCFQDKQNIYIV

LERPEPVQDLFDFITERGA-----------------LQEDLAR-----GFFWQVLEAVRHCHNCG-VLHRDIKDENILIDLSRG--EIKLIDFGSGA---
.|  |  .||...|..|.                  ..|  |.      .|.|.|..  ..|  . ..||||| ||||.| . .  .||.||||.     
MEYCE-GGDLWQYIKKRKKQKQKGNDLFHNMKQRKIFTEQQAKYKKAKFYFAQILQGLEYLHHKNNIIHRDIKPENILFDNNGKNYYIKIIDFGISKKYQ

--------------LLKDTVYTDFDGTRVYS----PPEWIRYHRYHGR---SAAVWSLGILLYDMVCGDIPFE----------------------HDEEI
               .|.  ...| ||  |     .|| .. . | ..   .. .||||..|| |. |  ||.                        ..|
QNNNCDTNQQQKMQIWKQQMMWTFCGTPNYMPQYTAPEVLQGQNYDHSKAYKCDIWSLGVILYEMLFGYYPFYDNNCEQHQQLITQWINNAYRKQLYQNI

IKGQVFFR--------QTVSSECQHLIK----WCLSLRPSDRPSFEEIRNHPWM
......|.        ...| |....|.     .|  .|. |..||.| ||||.
KQKNIQFPKFPWQQIPKHWSPEAKDFINDLLQKMLKKNPNKRITFEQILNHPWF

Kinase PIM1.AA MELK 122-374 33 3e-40 135.07 In-house 1-254 (254) Show / Hide
Range on Protein: 122-374
Range on HMM: 1-254/254
Sequence Identity: 33% (87 aa)

YQVGPLLGSGGFGSVYSGIRVADNLPVAIKHVEKDRISDWGELPNGTRVPMEVVLLKKVSSDFSGVIRLLDWFERPDSFVLILERPEPVQDLFDFITERG
|.|   .|.|||. |     .  |  |||| ..|... .  .||   ||  |.  ||...     . .|    |  | . ...|   |  ..||.| .. 
YEVHDEIGTGGFAKVKLACHILTNQMVAIKIMDKNQLGH--DLP---RVKTEMDALKNLRHQH--ICQLYHYIETEDKIFMVMEYC-PGGEMFDYIIRQD

ALQEDLARGFFWQVLEAVRHCHNCGVLHRDIKDENILIDLSRGEIKLIDFGSGALLKDTVYTD----FDGTRVYSPPEWIRYHRYHGRSAAVWSLGILLY
 |.|. .| || |.. |. . |  |  |||.| ||.|.|    ..||||||  |  |  .         |   |  || |.  .| |  | |||.|||||
RLEEEETRHFFRQIVSAIAYVHSQGYAHRDLKPENLLFDEDH-HLKLIDFGLCAKTKGRKDYHNLQTCCGSPAYAAPELIQGKQYIGSEADVWSMGILLY

DMVCGDIPFEHDE------EIIKGQVFFRQTVSSECQHLIKWCLSLRPSDRPSFEEIRNHPWM
 ..|| .||. |        |..|     . .| | ..|..  |   |  | |  .. ||||.
VLMCGFLPFDDDNMMIMYKKIMSGCYEEPKWLSPESKQLLRHMLQVDPKKRISMKNLLNHPWV

Kinase PIM1.AA QIK 212-374 30 5.9e-40 139.07 In-house 84-272 (272) Show / Hide
Range on Protein: 212-374
Range on HMM: 84-272/272
Sequence Identity: 30% (57 aa)

DLFDFITERGA--------------------LQEDLARGFFWQVLEAVRHCHNCGVLHRDIKDENILIDLSRGEIKLIDFGSGALLKDTV-YTDFDGTRV
..|| ... |                     ..|. ||  |||.. || .||. .. |||.| ||||.|    .||..||| . . |       . |.  
EMFDYLCKHGRKGVKMVNSPDIGDQVLMGVPMAENEARRWFWQICSAVHYCHKRNIVHRDLKAENILLDNNM-NIKIADFGFSNWFKQGQLLMTWCGSPP

YSPPEWIRYHRYHGRSAAVWSLGILLYDMVCGDIPFEHDEE------IIKGQVFFRQTVSSECQHLIKWCLSLRPSDRPSFEEIRNHPWM
|  ||      | |  . .||.|..|| .||| .||  .        .. |..     .|..|.|||.  | . |. | . . |..|.||
YAAPEMFEGKEYDGPKVDIWSMGVVLYVLVCGALPFDGKTLQNLRQRVLSGKFRIPFFMSQDCEHLIRHMLVVDPEHRYTIMQICQHRWM

Kinase PIM1.AA TSSK 212-272 47 7e-24 75.25 In-house 103-168 (289) Show / Hide
Range on Protein: 212-272
Range on HMM: 103-168/289
Sequence Identity: 47% (32 aa)

DLFDFITER------GALQEDLARGFFWQVLEAVRHCHNCGVLHRDIKDENILIDLSRGEIKLIDFG
||...| .|      |||.|..|| .|.|  .||..||...| |||.| |||| |   . |||.|||
DLLEYIQRRTQERCCGALHEEQARKWFRQMVSAVKYCHSHNVVHRDLKCENILLDKH-WNIKLTDFG

Kinase PIM1.AA TSSK 309-374 36 4.6e-16 49.2 In-house 212-289 (289) Show / Hide
Range on Protein: 309-374
Range on HMM: 212-289/289
Sequence Identity: 36% (29 aa)

VWSLGILLYDMVCGDIPFEHDE---------EIIK-GQVFFR----QTVSSECQHLIKWCLSLRPSDRPSFEEIRNHPWM
|||.|. || ||||  ||  |.         ....   | |.    ...|.||..||.  |...|. ||. .|| .|.||
VWSMGVILYIMVCGCMPF--DDDKSNIHKMLWQQQEHKVCFPKPHSCWISQECKDLIRHMLQPHPCNRPHINEICHHCWM

Kinase PIM1.AA TyrKc 122-374 20 3.3e-10 -57.61 SMART 1-280 (280) Show / Hide
Range on Protein: 122-374
Range on HMM: 1-280/280
Sequence Identity: 20% (62 aa)

YQVGPLLGSGGFGSVYSGIRVADNLPVAIKHVEKDRISDWGELPNGTRVPMEVVLLKKV-SSDFSGVIRLLDWFERP-------DSFVLILERPEPVQDL
 . |  ||.| || || |.     ..||.| . .|                |  ...|.   .   ..||.     .       .   ...|  .   ||
ITLGKKLGEGAFGEVYKGTWK---IQVAVKMLKEDA---------REDFMREARIMCKLGG-HHPNIVRLYGVCTQQGRNFMYIEPLMIVMEYMPH-GDL

FDFITERGA-LQEDLARGFFWQVLEAVRHCHNCGVLHRDIKDENILIDLSRGEIKLIDFG-SGALLKD------TVYTDFD---GTR--V---YSPPEWI
 |.. ...  |. .    | ||. .  .. |  .. |||.   |.|..  .  .|  ||| | ..  |      . | .     |..  .     .|| |
KDYLRKHRPKLCMKDLLSFCWQIACGMEYLHSKNCIHRDLAARNCLVGENH-TVKISDFGLSRDIYDDDQQGESKDYYRKKEHKGGKTMLPIRWMAPECI

RYHRYHGRSAA--VWSLGILLYDMV-CGDIPFEHD-----------EEIIKGQVFFRQTV---------SSECQHLIKWCLSLRPSDRPSFEEIRNHPWM
.|...   . .  ||| |.... .   |. | . .           | . .|    .            ..|   ..|.|    |.|||.|.||  |  .
NYGKF---TTKSDVWSFGVCMWEIFTYGQQPYPGMIQQMMSNQEVIEYVKQGYRMPQPPNDYPMSFVCCPDEMYQIMKQCWHEDPEDRPTFSEI--HECF





Kinase PIM1.AA TSSK 122-151 23 0.003999 6.08 In-house 1-46 (289) Show / Hide
Range on Protein: 122-151
Range on HMM: 1-46/289
Sequence Identity: 23% (11 aa)

YQVGPLLGSGGFGSVYSGIRVADNLP----------------VAIK
|.||  .|.| .. ||..    ...                 ||||
YNVGKKIGHGSYAKVYCAYSKKHKCKHNPRLRDDLRIKRHTHVAIK

Kinase PIM1.AA Pkinase_Tyr 122-151 38 0.004415 11.06 Pfam 1-34 (270) Show / Hide
Range on Protein: 122-151
Range on HMM: 1-34/270
Sequence Identity: 38% (13 aa)

YQVGPLLGSGGFGSVYSGIRV----ADNLPVAIK
 . |  ||.| ||.|| |.       ...|||.|
ITFGKKLGEGAFGEVYKGTWKGDPDNTKIPVAVK

Kinase PIM1.AA Pkinase_Tyr 349-371 43 0.122674 6.17 Pfam 247-269 (270) Show / Hide
Range on Protein: 349-371
Range on HMM: 247-269/270
Sequence Identity: 43% (10 aa)

HLIKWCLSLRPSDRPSFEEIRNH
.|.| |    |.|||.|.||...
DLMKQCWHYDPEDRPTFSEIHEQ