PLK3

Species: Mouse
Alias: PLK3, Cnk
External Links: MGI , Entrez Gene , Refseq cDNA , Refseq Protein , Phosphosite , iHOP
Annotation:

Classification

Group: Other
Family: PLK
Subfamily: PLK2

Sequence

Name Sequence Type Origin Length Description Download
PLK3.kin_dom Protein Kinase Domain Sugen global kinase HMM prediction 253 Kinase domain by global Sugen HMM Fasta, JSON
PLK3.AA Protein Sugen 648 None Fasta, JSON
PLK3.NA RNA Sugen 2358 None Fasta, JSON

Protein domain

Protein domains of PLK3.AA. The domains are annotated by HMM profiles from Pfam and SMART, as well as in-house data which includes HMMs of each individual kinase group, family and subfamily. Here is domain list in details, including sequence identity, significance and alignment. In particular, you can find can find the best hit kinase group/family/subfamily, which is helpful to understand the relationship between kinases.Kinase domain and best hit kinase group/family/subfamily are highlighted in red and blue. Visualized by pviz.

Usage: Zoom in selected region by dragging mouse and zoom out by double-clicking.

Domain Protein name Domain Name Range Identity (%) Significance Score Profile Source Profile Range (length) Alignment
Kinase PLK3.AA PLK2 63-315 69 1.8e-228 743.33 In-house 1-257 (257) Show / Hide
Range on Protein: 63-315
Range on HMM: 1-257/257
Sequence Identity: 69% (179 aa)

YTKGRLLGKGGFARCYEATDTESGIAYAVKVIPQSRVAKPHQREKILNEIELHRDLQHRHIVRFSHHFEDADNIYIFLELCSR----KSLAHIWKARHTL
|..|.||||||||||||.||......||||..|.|||||||||||...||||||.|.|||||.|.|||||.|||||.||.|||    ||.||.||.||.|
YCRGKLLGKGGFARCYEMTDMDTHYVYAVKIVPHSRVAKPHQREKMEREIELHRQLRHRHIVQFHHHFEDRDNIYILLEYCSRQVPLKSMAHMWKVRHHL

LEPEVRYYLRQILSGLKYLHQRGILHRDLKLGNFFITDNMELKVGDFGLAARLEPPEQRKKTICGTPNYVAPEVLLRQGHGPEADVWSLGCVMYTLLCGS
.|||||||.|||.|||.||||..|.|||||||||||.||||.|.|||||||||||.|....|.||||||.|||||.||||..|.|.|.|||.|||.|||.
TEPEVRYYMRQIVSGLRYLHQQCIIHRDLKLGNFFINDNMEVKIGDFGLAARLEPEEHCHRTMCGTPNYIAPEVLNRQGHSCESDIWALGCIMYTMLCGR

PPFETADLKETYRCIKQVHYTLPASLSLPARQLLAAILRASPRDRPSIEQILRHDFF
||||||.||||||||...||..|..||.|||.|.|..|...|.||||...|.|||||
PPFETANLKETYRCIRHNHYHMPTHLSPPARHLIARMLSPDPEDRPSLDHIIRHDFF

Kinase PLK3.AA PLK 63-315 58 1.1e-189 622.68 In-house 1-258 (258) Show / Hide
Range on Protein: 63-315
Range on HMM: 1-258/258
Sequence Identity: 58% (152 aa)

YTKGRLLGKGGFARCYEATDTESGIAYAVKVIPQSRVAKPHQREKILNEIELHRDLQHRHIVRFSHHFEDADNIYIFLELCSRKSLAHIWKAR-HTLLEP
|..|..|||||||.|||.|| ...  ||.||.|.|...|||||||. .|||.||.|.|..||.| |.|||..|.||.||.|...||.|..|.| ..| ||
YERGHFLGKGGFAKCYEMTDIHTKQVYAIKVVPKSLMQKPHQREKMKQEIEIHRQLHHPNIVKFHHFFEDHENVYIVLEYCHNRSLMHYHKRRAKRLTEP

EVRYYLRQILSGLKYLHQRGILHRDLKLGNFFITDNMELKVGDFGLAARLEPPEQRKKTICGTPNYVAPEVL--LRQGHGPEADVWSLGCVMYTLLCGSP
|||||..|| .|||||||..|.||||||||.|..|||..|.||||||.|||....||||.||||||.|||||   .|||. |.|.|||||.|||||.|.|
EVRYYMYQIVQGLKYLHQHRIIHRDLKLGNLFLNDNMHVKIGDFGLATRLEYDGERKKTMCGTPNYIAPEVLDGNKQGHSYEVDCWSLGCIMYTLLIGKP

PFETADLKETYRCIKQVHYTLPAS--LSLPARQLLAAILRASPRDRPSIEQILRHDFF
||||.|.||||..||. ||..|..  .| .|..|....|.  |..||.|.|||.|.||
PFETKDVKETYKRIKHNHYSFPEHCPISDEAKDLIQKMLNWNPDERPTIDQILQHPFF

Kinase PLK3.AA PLK-Unclassified 63-315 49 1.5e-130 440.01 In-house 1-264 (264) Show / Hide
Range on Protein: 63-315
Range on HMM: 1-264/264
Sequence Identity: 49% (131 aa)

YTKGRLLGKGGFARCYEATDTESGIAYAVKVIPQSRVAKPHQREKILNEIELHRDLQHRHIVRFSHHFEDADNIYIFLELCSRKSLAHIWKAR-------
| .|..|||||||.||.... |.   ||.|.|| |   |  .|.| ..||..| .| |..||.| | ||| .|.|| ||.|. ..| .. | |       
YHRGHFLGKGGFAKCYQVKNIETKKIYAAKIIPKSSLTKNRARQKLISEIKIHKSLHHKNIVKFEHCFEDHENVYILLEYCPNGTLMEYIKRRNFQLFEK

HTLLEPEVRYYLRQILSGLKYLHQRGILHRDLKLGNFFITDNMELKVGDFGLAARLEPPEQRKKTICGTPNYVAPEVL--LRQGHGPEADVWSLGCVMYT
  | |.||..|. ||. .||||||..| |||||||| |..||||.| .|||||..||  ...|||||||||| |||.|    |||. | |.||.||. ||
KRLTEYEVKCYTYQIVQALKYLHQNRIIHRDLKLGNIFLNDNMEVKICDFGLATKLENDGEKKKTICGTPNYIAPEILDGKHQGHSYEVDCWSFGCILYT

LLCGSPPFETADLKETYRCIKQVHYTLP--ASLSLPARQLLAAILRASPRDRPSIEQILRHDFF
|| | ||||| | | ||. ||.  |  |  . .|  |. |.  ||   |  ||.| ||. |.|.
LLIGKPPFETKDVKQTYKKIKCNQYSFPEPCHISDNAKDLIQHILNWNPDQRPTIDQIMMHPFY

Kinase PLK3.AA PLK1 63-315 55 2.9e-126 417.18 In-house 1-253 (253) Show / Hide
Range on Protein: 63-315
Range on HMM: 1-253/253
Sequence Identity: 55% (140 aa)

YTKGRLLGKGGFARCYEATDTESGIAYAVKVIPQSRVAKPHQREKILNEIELHRDLQHRHIVRFSHHFEDADNIYIFLELCSRKSLAHIWKARHTLLEPE
|.||| |||||||.||| .|..    .|.||.|.| . |.|||.|.  ||..||.|.|||||.| |.||| .|.|| ||||.|.||  . | | .. |||
YEKGRFLGKGGFAHCYEIRDKDTKEVFAGKVVPKSLLIKQHQRDKMTQEIQIHRQLHHRHIVKFHHFFEDKQNVYIVLELCRRRSLMELHKRRKAITEPE

VRYYLRQILSGLKYLHQRGILHRDLKLGNFFITDNMELKVGDFGLAARLEPPEQRKKTICGTPNYVAPEVLLRQGHGPEADVWSLGCVMYTLLCGSPPFE
 |||..||. | .|||.  |.|||||||| |. |....|.|||||| ..|    ||||.||||||.||||| ..||  | |.||.||.||.|| |.||||
CRYYMYQIVEGCQYLHNNKIIHRDLKLGNLFLNDHLQVKIGDFGLATKCEYDGERKKTLCGTPNYIAPEVLNKKGHSFEVDIWSIGCIMYILLFGQPPFE

TADLKETYRCIKQVHYTLPASLSLPARQLLAAILRASPRDRPSIEQILRHDFF
|  |||||  ||.  |..| ..| ||.||. ..| . |  || |||.|. .||
TKCLKETYSRIKKNEYRIPSHISQPAAQLIRKMLDPDPTRRPTIEQVLNDEFF

Kinase PLK3.AA S_TKc 63-315 31 1.3e-98 334.84 SMART 1-231 (231) Show / Hide
Range on Protein: 63-315
Range on HMM: 1-231/231
Sequence Identity: 31% (85 aa)

YTKGRLLGKGGFARCYEATDTESGIAYAVKVIPQSRVAKPHQREKILNEIELHRDLQHRHIVRFSHHFEDADNIYIFLELCSR--KSLAHIWKARHT---
|...|..|||.|...| ......|  .|.|.|.          |.|..||....  .| .||..  .|.| |..|...|.|.    .| .. | | .   
YEILRKIGKGAFGKVYKCRHKKTGRIVAIKIIK----------EHIRREIQILKK-HHPNIVKLYDVFQD-DHLYMVMEYCDGDLGDLFDYIKKRGRHGL

---LLEPEVRYYLRQILSGLKYLHQRGILHRDLKLGNFFITDNMELKVGDFGLAARLEPPEQRKKTICGTPNYVAPEVLLRQGHGP-EADVWSLGCVMYT
   . | ..|.|..||...|.|.|..||.|||||  | ....  ..|..|||||..|       .|.||||.|.|||||   |.|. ..|.||.||..| 
RFPFPE-HARFYMYQICCALEYCHSHGIIHRDLKPENILLDE--HIKICDFGLARQL-------TTFCGTPWYMAPEVL---GYGKCKCDWWSCGCILYE

LLCGSPPFETADLKETYRCIKQVHYTLPASLSLPARQLLAAILRASPRDRPSIEQILR-------HDFF
.||| |||.  ....... |.          | .|....  .|.  |..||.. ..|.       | .|
MLCGYPPFP--QMQMMFKKIG----------SPEAKDFIRKCLQKDPEKRPTA-EALQDEWDIKCHPWF

Kinase PLK3.AA CAMK 68-315 20 7.5e-94 302.77 In-house 1-425 (425) Show / Hide
Range on Protein: 68-315
Range on HMM: 1-425/425
Sequence Identity: 20% (88 aa)

LLGKGGFARCYEATDTESG------------IAYAVKVIPQSRVAK-------------------------PHQREKILNEIELHRDLQ-------HRHI
 ||.|.|.  .........              .|.|.|. ... .                         |. |.....|||... ||       |..|
TLGRGSFGKVKLCIHKNTTGKERVHHIYTNGQKVAIKIIDKKKLKDKQNQDYSNCYKIDKSKCKHRYCWRRPKDRKNVRREIEIMKKLQGIGNKLDHPNI

VRFSHHFEDADN-------------------IYIFL---ELCSRK----S-LAHIWKARH--------------TLLEPEVRYYLRQILSGLKYLHQRGI
... ...||...                   .|...   |.||        . .| . ..               . | |.|.| |||.|...|.|...|
IKLYEVYEDPHYFKNTNDYETSKQVFTKDKHMYMVMEIMEYCSGGELFDDLFDYIVEHGCYGEEFDQFDIVERGRFTEREARRYFRQICSAVHYCHSHNI

LHRDLKLGNFFITDNM-----------------ELKVGDFGLAARLEP-----------------------PEQRKKTICGTPNYVA-PEVLLR------
 |||||. |  ..||.                  .|. |||.|....|                       . |  || |||| |.| ||||..      
VHRDLKPENILLDDNNDDSDPVEHDEIFDWNNNNIKIIDFGFANKFDPGENNFMCSDYKGGEMHNQWTTPTEGQKMKTFCGTPEYMAAPEVLNGKGHCNM

--------QGHGPEADVWSLGCVMYTLLCGSPPFETA-------------DLKETYRCIKQVHYT-LPASLSL-----------------------PARQ
        ...||..|.||.|...|..||| |||.               ...|... |..  |.  |  .|                         ...
QNATDEEKPYYGPKCDMWSCGVILYIMLCGYPPFYGDCDNEICEDEWIGMNDYELFEKIMKGKYDFPPPYFSPISCNYGPEWWDDISDEFHHFVSQECKD

LLAAILRASPRDRPSIEQILRHDFF
|.  .|.  | .|..|||.|.| ..
LIRKMLQVDPEKRMTIEQCLNHPWM

Kinase PLK3.AA Pkinase 63-315 31 7e-87 299.75 Pfam 1-293 (293) Show / Hide
Range on Protein: 63-315
Range on HMM: 1-293/293
Sequence Identity: 31% (94 aa)

YTKGRLLGKGGFARCYEATDTESGIAYAVKVIPQSRVAKPHQREKILN--EIELHRDLQHRHIVRFSHHFEDADNIYIFLELCSRK----SLAHIWK-AR
|..|| .|.|.|...|....  .|. .|||.|. .  .|. ...  ..  ||.... |.| .|||. . ||| |.||. .|.|       .|... .  |
YHIGRKIGSGSFGCVYKCHHKGTGKIVAVKIIKKR-HEKSWKDQTHRRLSEIQIMKRLNHPNIVRLYDWFEDKDHIYMVMEYCEGGLYVMDLFDYISTWR

HTLL---EPEVRYYLRQILSGLKYLHQRGILHRDLKLGNFFITDNMEL----KVGDFGLAARL-EPPEQRKKTICGTPNYVAPEVLL-RQGHGPEADVWS
|. .   | |.. |..|||.||.|.|..||.|||||. |..| .|...    |..|||||. . . . .  .|.||||.|.||||.. .|..||..|.||
HGCFYFSEWECKFYMYQILRGLEYCHSMGIIHRDLKPENILIDNNGHIDACVKICDFGLAKQFDY-NNS-MTTFCGTPWYMAPEVIRGGQYYGPKVDMWS

LGCVMYTLLCGSPPFETA------DLKETYRCIKQVHYTLPASLS---------------------LPARQLLAAILRASPRDRPSIEQILRHDFF
.||..| .||| |||  .      | .. .. |..  .  . . .                      ......  .|.  | .||..|||| |..|
CGCILYEMLCGRPPFPGHCWHDNHDQMQMICRIMGPPLHFDWPWWCSISYFFFRHWHFHWTFHNWSEECKDFIKWCLCKDPKKRPTAEQILQHPWF

Kinase PLK3.AA CAMKL 63-315 29 7.7e-87 277.14 In-house 1-297 (297) Show / Hide
Range on Protein: 63-315
Range on HMM: 1-297/297
Sequence Identity: 29% (88 aa)

YTKGRLLGKGGFARCYEATD-TESGIAYAVKVIPQSRVA-KPHQREK-----------ILNEIELHRDLQ---HRHIVRFSHHFEDADN------IYIFL
|. |. ||||.|.    ||.    |. .|.|.|  ..   .|. . .           |  ||.... |.   | .|... ...|. ..      ||...
YRIGKTLGKGSFGKVKLATHIRTTGEKVAIKIIDKKKIWNDPWMKKNKCGQKHESDMRIRREIQIMKMLNIGKHPNIIKLYEVIETPEHDIETKKIYLVM

ELCSRK---SLAHIWKARH---TLLEPEVRYYLRQILSGLKYLHQRGILHRDLKLGNFFITDNM--ELKVGDFGLAARLEP----PEQRKKTICGTPNYV
|.||      . .| | .|    . |.| | | |||.|...|.|..|| |||.|. |  ...|.   .|. |||...  .|    |.|  || ||.|.| 
EYCSGGEMDLFDYIVKHGHRRGRMPEHEARRYFRQIVSAVNYCHSHGIVHRDIKPENILLDENGNNNIKIIDFGFSNMYRPCIFGPGQKLKTFCGSPPYM

APEVLLR--Q-GHGPEADVWSLGCVMYTLLCGSPPFETADLK-------ETYRCIKQVHYTLPASLSL-PARQLLAAILRASPRDRPSIEQILRHDFF
|||....  .  .||..|.||.| ..|...||  ||. ....       . |. |..  |  |  ... ..|.|.  .|   | .||.|.||..| ..
APEIFQGNNKPYDGPKVDIWSCGVILYAMVCGYLPFDDDTYNKQGKDNIYLYWKIMCG-YYPPIWYHVSDCRDLIRKMLQVNPEKRPTIHQIMNHPWM

Kinase PLK3.AA SAK 63-315 40 2.1e-79 270.08 In-house 1-254 (254) Show / Hide
Range on Protein: 63-315
Range on HMM: 1-254/254
Sequence Identity: 40% (102 aa)

YTKGRLLGKGGFARCYEATDTESGIAYAVKVIPQSRVAKPHQREKILNEIELHRDLQHRHIVRFSHHFEDADNIYIFLELCSRKSLAHIWKAR-HTLLEP
|  . ||||||||  | |   . .   |.|.| .  . |    ... ||.|.|  |.|  |.    .|||.  .|. ||.|    .    | | .   | 
YQVQHLLGKGGFACVYRAKCIHTHQEVAIKMIDKKLMQKTGMVQRVRNEVEIHCQLKHPSILELYNYFEDNNYVYLVLEMCHNGEMHRYMKHRMRPFTEE

EVRYYLRQILSGLKYLHQRGILHRDLKLGNFFITDNMELKVGDFGLAARLEPPEQRKKTICGTPNYVAPEVLLRQGHGPEADVWSLGCVMYTLLCGSPPF
| | ...||. |. |||  ||.|||| | |  .| .|..|. |||||. |. |. .  |.||||||..||.  |  || ..|||||||..|||| | |||
EARHFMHQIVIGMLYLHSHGIMHRDLTLSNILLTRDMHCKIADFGLATQLKMPHEKHYTMCGTPNYISPEIATRTAHGLQSDVWSLGCMLYTLLIGRPPF

ETADLKETYRCIKQVHYTLPASLSLPARQLLAAILRASPRDRPSIEQILRHDFF
.|   |.|   .    | .|| ||. |. |.  .||  | .| ... .| | | 
DTDAVKNTLNKVMMAEYIMPAHLSMEAQDLIHKMLRKNPHERITLSTVLCHPFM

Kinase PLK3.AA MARK 63-315 34 5.2e-76 247.98 In-house 1-262 (262) Show / Hide
Range on Protein: 63-315
Range on HMM: 1-262/262
Sequence Identity: 34% (91 aa)

YTKGRLLGKGGFARCYEATDTESGIAYAVKVIPQSRVAKPHQREKILNEIELHRDLQHRHIVRFSHHFE--DADN-IYIFLELCSRKSLAHIWKAR--HT
|  .. .|.|..|  . |... .|. .|.|...  .  .|......  |||... |.| .|... | .|  .  . ||. .|..|...| .  ||.  . 
YKMLKTIGHGSYAKVKLACHKHTGRKVAIKIYEKFKLNDPQWMKNVMREIEIMKKLDHPNIIKLFHVIEQDTEQHQIYLIMEYASGGELYDYIKAHPNGR

LLEPEVRYYLRQILSGLKYLHQRGILHRDLKLGNFFITDNM--ELKVGDFGLAARLEPPEQRKKTICGTPNYVAPEVLLRQG-HGPEADVWSLGCVMYTL
| |.| | . |||.|...|.|...| |||.|. |  | .|.    |  |||....  ||.|. .| |||| | |||..|..   ||..|.|||| |.|..
LHEEEARRIFRQIVSAVNYCHSKNIVHRDIKPENILIDENGNHNIKIIDFGFSICI-PPGQKLNTFCGTPPYMAPEIFLKKPYDGPKVDIWSLGVVLYFM

LCGSPPFE--TADLKETYRCIKQVHYTLPASLSLPARQLLAAILRASPRDRPSIEQILRHDFF
.||. ||.  |.|.|| |. |   .|. |  .|  .|.|.  .| . | .||.||.|..| ..
VCGYFPFDGDTQDYKELYKKILRGKYDIPCHVSKECRNLIQRLLTVNPEERPTIEEIMKHPWM

Kinase PLK3.AA ULK 63-315 26 7.7e-68 231.69 In-house 1-324 (324) Show / Hide
Range on Protein: 63-315
Range on HMM: 1-324/324
Sequence Identity: 26% (86 aa)

YTKGRLLGKGGFA-RCYEATDTES---GIAYAVKVIPQS-RVAKPHQRE------KILNEIELHRDLQ------HRHIVRFSHHFEDA--DNIYIFLELC
| . . |||| |.   |.... ..   . ..|.|.|...    |....|      .. |||.. . |       | |||.. . ||..  .||||..|.|
YCLNHCLGKGSFGVKVYKGRNKKTNTQNQYVACKMIDKKKMNKKKNEQEGQYMWQLLKNEIQIMKKLKELKHPNH-HIVKLYDWFETSNHNNIYIIMEYC

SRKSLAHIWKARHT---------LLEPEVRYYLRQILSGLKYLHQRGILHRDLKLGNFFITDN------------MELKVGDFGLAARLEPPE---QRKK
    | .. | ...         | |.|.. ...||..|.|.||...| |||.|. |  |...              ||..|||.|  .. ..   |  .
NGGDLEQYIKKNKKLPETEEKKRLSEQEAIQFFKQICNGFKELHKHNIIHRDIKPQNILIHNGQPKTDSKKVHPNGVLKIADFGFAKHVDNNNMEQQMCQ

TIC------GTPNYVAPEVLLRQG----HG-PEADVWSLGCVMYTLLCGSPPFETADLKETY----------------RCIKQVHYTLPA---SLSLPAR
|..      ||| | ||..| .||    ..  ..|.|||||..| .| |..||..    ..|                 . ... . .|     .|   .
TCVNEKRIKGTPLYMAPQILQGQGEQKPYYDYKCDIWSLGCIFYEMLYGKYPFFSW-FNDQYLYIQKLINNGKEQQIYIKNQPIQFPKPPKDPKISPECK

QLLAAILRASPRDRPSIEQILRHDFF
.|.   |   ..|| |.|.|. | .|
DLIRRMLQYDEKDRISWEEIFNHPWF

Kinase PLK3.AA ULK 63-315 26 2.6e-67 229.95 In-house 1-329 (329) Show / Hide
Range on Protein: 63-315
Range on HMM: 1-329/329
Sequence Identity: 26% (87 aa)

YTKGRLLGKGGFARCYEATDTES----GIAYAVKVIPQS-RVAKPHQRE------KILNEIELHRDL--------QHRHIVRFSHHFEDA--DNIYIFLE
| . . |||| |.. |.... ..    ....|.|.|...    |....|       . |||.. . |        .| .||.. . ||..  .||||..|
YCLNHCLGKGSFGKVYKGRNKKTKDYVNEKVACKMIDKQKMNQKNNEQEGQYMWQLLKNEIKIMKKLKSPNRHKNHHPNIVKLYDWFETSNHNNIYIIME

LCSRKSLAHIWKARHT----------LLEPEVRYYLRQILSGLKYLHQRGILHRDLKLGNFFITDN------------MELKVGDFGLAARLEPP---EQ
.|    | .. | ...          | |.|.. ...|||.|.|.||...| |||.|. |  |...            . ||..|||.|  .. .   .|
YCNGGDLEQYIKKNKKLPEDTEEKKRLSEQEAIQFFKQILNGFKELHKHNIIHRDIKPQNILIHNGQPKTDSKKVHPNGVLKIADFGFAKHVDNDNMEQQ

RKKTIC------GTPNYVAPEVLLRQG----HG-PEADVWSLGCVMYTLLCGSPPFETADLKETY--RCIKQVHY---------TLPAS---------LS
  .|        ||| | ||..| .||    ..  ..|.|||||..| .| | |||..    ..|   ..| . .         . |           .|
MMMTCVNEKRLCGTPLYMAPQILQGQGEQKPYYDYKCDIWSLGCIFYEMLYGKPPFYAW-FNDQYLQIIQKLINNPPPWPQQIKKQPLQFPKDGNDPQIS

LPARQLLAAILRASPRDRPSIEQILRHDFF
   ..|.   |   ..|| |.|... | .|
PECKDLIRRMLQYDEKDRISWEELFNHPWF

Kinase PLK3.AA TyrKc 63-315 23 1.4e-16 45.54 SMART 1-280 (280) Show / Hide
Range on Protein: 63-315
Range on HMM: 1-280/280
Sequence Identity: 23% (69 aa)

YTKGRLLGKGGFARCYEATDTESGIAYAVKVIPQSRVAKPHQREKILNEIELHRDL--QHRHIVRFSHHFEDA-------DNIYIFLELCSRKSLAHIW-
 |.|. || | | . |..| .   |  |||..  .       || ...|... . |  .| .|||.     .        . ..| .|...  .| .   
ITLGKKLGEGAFGEVYKGTWK---IQVAVKMLKEDA------REDFMREARIMCKLGGHHPNIVRLYGVCTQQGRNFMYIEPLMIVMEYMPHGDLKDYLR

KARHTLLEPEVRYYLRQILSGLKYLHQRGILHRDLKLGNFFITDNMELKVGDFGLAARLEPP--------EQRKKT-ICGTP----NYVAPEVLLRQGHG
| |..|  ..  ..  || .|  |||.... ||||   |  ...|   |..||||.  ..            |||.  .|         |||..      
KHRPKLCMKDLLSFCWQIACGMEYLHSKNCIHRDLAARNCLVGENHTVKISDFGLSRDIYDDDQQGESKDYYRKKEHKGGKTMLPIRWMAPECINYGKFT

PEADVWSLGCVMY-TLLCGSPPFET-----ADLKETYRCIKQVHYTLPASL---------SLPARQLLAAILRASPRDRPSIEQILRHDFF
.. |||| | .|.  .  | .| .       . .| ....|| ..  .            .    |.     .. | |||. ..|  |..|
TKSDVWSFGVCMWEIFTYGQQPYPGMIQQMMSNQEVIEYVKQGYRMPQPPNDYPMSFVCCPDEMYQIMKQCWHEDPEDRPTFSEI--HECF

Kinase PLK3.AA Pkinase_Tyr 63-275 27 4.8e-14 48.2 Pfam 1-231 (270) Show / Hide
Range on Protein: 63-275
Range on HMM: 1-231/270
Sequence Identity: 27% (63 aa)

YTKGRLLGKGGFARCYEATDT----ESGIAYAVKVIPQSRVAKPHQ--REKILNEIELHRDL-QHRHIVRFSHHFE-DADN--IYIFLELCSRKSLAHIW
 |.|. ||.| | . |..| .    . .|  |||....   | ..|  ||. ..|... . | .| .|||.      . .   ||| .|..   .| .  
ITFGKKLGEGAFGEVYKGTWKGDPDNTKIPVAVKMLKE--GAMHEQNCREDFMREAKIMKQLGHHPNIVRLYGVCTDQGEPNQIYIVMEYMPHGDLLDYL

KA----RHTLLEPEVRYYLRQILSGLKYLHQRGILHRDLKLGNFFITDNMELKVGDFGLAARL-EPPEQ-RKKTICGTP-NYVAPEVLLRQGHGPEADVW
..    .. |  ..   . .|| .|. ||..... ||||   |  .|.|.  |..|||||  . .  .  ||.. .  |    |||..       . |||
RKHREDKQPLTMKDLLQMCWQIAKGMEYLESKNCIHRDLAARNCLVTENNVVKICDFGLARDIYNDDYYYRKRGGGKLPIKWMAPECINYGKFTTKSDVW

SLGCVMYTLLC-GSPP-FETADLKETYRCI-KQ
| | .|. ..  |  | ..  .  | |. | ..
SFGVLMWEIFTYGEQPTYPGMSNEEVYEYIYED

POLO_box PLK3.AA POLO_box 472-535 31 5.4e-19 73.76 Pfam 1-74 (74) Show / Hide
Range on Protein: 472-535
Range on HMM: 1-74/74
Sequence Identity: 31% (23 aa)

YSNKFGFGYQLSSRRVAVL-FNDGTHMALSANRK-TVHYNP--TSTKHFSFSMGS------VPRALQPQLGILR
|..| |..||||   | |. |||.|...|..|.| .|.|    .. ... ... .      .|  || .| .|.
YRTKYGIMYQLSNGTVQVNFFNDHTKIILCPNMKYAVTYIDHDPNWQRQTYPLSTILEHGCYPEDLQKKLTYLK

POLO_box PLK3.AA POLO_box 569-639 36 1.1e-21 83.16 Pfam 1-74 (74) Show / Hide
Range on Protein: 569-639
Range on HMM: 1-74/74
Sequence Identity: 36% (27 aa)

VKTDQALLMLFSDGTVQVNFYGDHTKLILSGWEPLLVTFVA--RNRSACTYLASHLRQLGC-SPDLRQRLRYAL
 .|.... ...|.|||||||. ||||.||. .. ..||. .  .|.   ||  |.. . || ..||...|.|. 
YRTKYGIMYQLSNGTVQVNFFNDHTKIILCPNMKYAVTYIDHDPNWQRQTYPLSTILEHGCYPEDLQKKLTYLK