Gene STK33 (Mouse)

STK33

Species: Mouse
Alias: STK33
External Links: Entrez Gene , Refseq cDNA , Refseq Protein , Phosphosite , iHOP
Annotation:

Classification

Group: CAMK
Family: STK33

Sequence

Name Sequence Type Origin Length Description Download
STK33.kin_dom Protein Kinase Domain Sugen global kinase HMM prediction 267 Kinase domain by global Sugen HMM Fasta, JSON
STK33.NA RNA Sugen 2221 None Fasta, JSON
STK33.AA Protein Sugen 491 None Fasta, JSON

Protein domain

Protein domains of STK33.AA. The domains are annotated by HMM profiles from Pfam and SMART, as well as in-house data which includes HMMs of each individual kinase group, family and subfamily. Here is domain list in details, including sequence identity, significance and alignment. In particular, you can find can find the best hit kinase group/family/subfamily, which is helpful to understand the relationship between kinases.Kinase domain and best hit kinase group/family/subfamily are highlighted in red and blue. Visualized by pviz.

Usage: Zoom in selected region by dragging mouse and zoom out by double-clicking.

Show/hide domain list
Domain Protein name Domain Name Range Identity (%) Significance Score Profile Source Profile Range (length) Alignment
Kinase STK33.AA CAMK-Unique 111-377 37 1.1e-164 547.76 In-house 1-363 (363) Show / Hide 
Range on Protein: 111-377
Range on HMM: 1-363/363
Sequence Identity: 37% (136 aa)

YTFGRILGQGSFGMVFEAIDKETGAKWAIKKVNKEKAGSSAMKL------------------LEREVSILKTVNHQHIIHLEQV----FESPQ-------
|...||.|.|.||.|.|..|.||| |||.|.|.|...|....|.                  |.||..|.|.|.|..||.|...    |. ..       
YKMHRIIGHGNFGHVYECMDRETGKKWACKMVKKQTHGNKKQKQQRNFDLRYKITEKRRDMKLKREHQIWKMVDHPNIIKLYDWNNPIFCDRKYPLCDLI

--------KMYLVMELCEDGELKAVMDQ--------------------RGHFSE--NETRLIIQSLASAIAYLHNKDIVHRDLKLENIMVKSSFID----
        .||.|||.|..|.|......                    .|||||  ..|..|.|.|.||.||.|..||||||||||||||..||.|    
IKTPRALPYMYIVMEYCQGGDLFDWIQKWDEFYFNFIIKFDFNILKRCQGHFSERCWDTCFIMQCLLSAVAYMHSQDIVHRDLKLENIMVCYSFKDNNHH

---DNNEMNLNIKVTDFGLSVQKHGSRSEGMMQTTCGTPIYMAP--------------EVINAHDYSQQC----DIWSIGVIMFILLCGEPPFLANSEE-
   .....|..||..||||.......... ||||.||||.||||              ||||...|.|||    ||||.||||...|||.||| ...|. 
RDFPYDWSNWHIKLCDFGLCCHYNHNKMCHMMQTMCGTPCYMAPEIVFCKNYQEMTRDEVINMQCYDQQCSPASDIWSLGVIMYYMLCGCPPFDCECEDR

-------KLYELIKKGEL-RFENPVWES---VSDSAKNTLKQLMKVDPAHRITAKELLDNQWL
       ...| |.||.. .|....|..   .|..||...|..|.|||.||..|||||..||.
DYENHDKEIFECICKGDYCNFDWKMWHGPDYISQEAKDFVKCCMTVDPDHRWSAKELLEHQWI
Kinase STK33.AA CAMK 116-377 25 3.8e-121 392.32 In-house 1-425 (425) Show / Hide 
Range on Protein: 116-377
Range on HMM: 1-425/425
Sequence Identity: 25% (109 aa)

ILGQGSFGMVFEAIDKETG------------AKWAIKKVNKEKAG--------------------------SSAMKLLEREVSILKT-------VNHQHI
.||.|||| |...|.|.|.             |.||| ..|.|.                            . .| ..||..|.|.       ..| .|
TLGRGSFGKVKLCIHKNTTGKERVHHIYTNGQKVAIKIIDKKKLKDKQNQDYSNCYKIDKSKCKHRYCWRRPKDRKNVRREIEIMKKLQGIGNKLDHPNI

IHLEQVFES-------------------PQKMYLVM---ELCEDGEL----KAVMDQRGH---------------FSENETRLIIQSLASAIAYLHNKDI
|.| .|.|.                   ...||.||   |.|. |||         ..|.               |.| |.| ... ..||..|.|...|
IKLYEVYEDPHYFKNTNDYETSKQVFTKDKHMYMVMEIMEYCSGGELFDDLFDYIVEHGCYGEEFDQFDIVERGRFTEREARRYFRQICSAVHYCHSHNI

VHRDLKLENIMVKSSFIDDNN--------EMNLNIKVTDFGLSVQKHGSRSEG---------------------MMQTTCGTPIYMA-PEVINA------
||||||.|||.. ... |...        . | |||..|||.. .. .. ..                      .|.| |||| ||| |||.|       
VHRDLKPENILLDDNNDDSDPVEHDEIFDWNNNNIKIIDFGFANKFDPGENNFMCSDYKGGEMHNQWTTPTEGQKMKTFCGTPEYMAAPEVLNGKGHCNM

--------HDYSQQCDIWSIGVIMFILLCGEPPFLAN-------------SEEKLYELIKKGELRFENPV------------WESVSDS--------AKN
          |...||.||.|||..|.|||.||| .              ....|.| |.||. .|. |             | ..||.        .|.
QNATDEEKPYYGPKCDMWSCGVILYIMLCGYPPFYGDCDNEICEDEWIGMNDYELFEKIMKGKYDFPPPYFSPISCNYGPEWWDDISDEFHHFVSQECKD

TLKQLMKVDPAHRITAKELLDNQWL
 ......||| .|.|... |. .|.
LIRKMLQVDPEKRMTIEQCLNHPWM
Kinase STK33.AA CAMK1 111-377 39 7.89999999999e-118 344.11 In-house 1-276 (276) Show / Hide 
Range on Protein: 111-377
Range on HMM: 1-276/276
Sequence Identity: 39% (112 aa)

YTFGRILGQGSFGMVFEAIDKET---GAKWAIKKVN-KEKAGSSAM---KLLEREVSILKTV---NHQHIIHLEQVFESPQKMYLVMELCEDGELKAVMD
| || ..| |.|. |.....|||   | ..|||  . |.    . |   ..||.|..|.|.|   .|..|| .. ..||. . ||||||.  |||     
YEFGKEIGRGAFSEVYLCTHKETQTNGKQYAIKCIDKKKFMKKKDMQKQEALENEIEIMKKVSKIDHPNIIKFYEWYESDNHFYLVMELVTGGELFDRIV

QRGHFSENETRLIIQSLASAIAYLHNKDIVHRDLKLENIMVKSSFIDDNNEMNLNIK--VTDFGLSVQKHGSRSEGMMQTTCGTPIYMAPEVINA---HD
..|...|.. |.|.. ..||. |.| |.||||||| ||.  ..      .. .  ||  . |||||  |  .  |..|.| |||| |.||||..      
EKGNYTEKDARHIMKQILSAVEYMHSKGIVHRDLKPENLLYYD------KDEDSKIKRSIADFGLS--KIFDHDENLMKTACGTPGYVAPEVLECKKDKP

YSQQCDIWSIGVIMFILLCGEPPFLANS-EEKLYELIKKGELRFENPVWESVSDS-AKNTLKQLMKVDPAHRITAKELLDNQWL
|.. ||.|||||| .||||| ||| ... ...|.|.|||.|..| .| | ..||. ||. .|....|||  |.|... |.  |.
YDKACDMWSIGVITYILLCGYPPFYDENVDNELFEKIKKCEYEFPSPWWDNISDQEAKDFIKHMLEVDPKKRYTCEQCLNHPWI
Kinase STK33.AA Ciliate-E2a 111-377 37 5e-108 319.06 In-house 1-275 (275) Show / Hide 
Range on Protein: 111-377
Range on HMM: 1-275/275
Sequence Identity: 37% (105 aa)

YTFGRILGQGSFGMVFEAIDKETGAKWAIKKVNKEKAGSSA--MKLLEREVSILKTVNHQHIIHLEQVFESPQKMYLVMELCEDGELKAVMDQRGHFSEN
| | ...|.|.|| |. |  |.|| . |.||..| |.  .    . ...|..|.....| .|| |  |.|. .  |||||.|| |||.  . | . | |.
YKFIKKIGKGNFGSVYLAQHKQTGKQFAMKKFIK-KMYQQKKGKEYFMNEINIMRQLDHPNIIKLYEVYEDENNYYLVMEYCEGGELYDKIKQCKRFFEE

--ETRLIIQSLAS-AIAYLHNKDIVHRDLKLENIMVKSSFIDDNNEMNLNIKVTDFGLSVQKHGSRSEGMMQTTCGTPIYMAPEVINAHD------YSQQ
  | . |.| | . ...|.|.. |.|||||.|||. |.  .. |.  |..||. ||||. ..  . ..  | . |||| |.||||.|  .      |...
IQEICDIMQQLLWQGLHYMHQRNIMHRDLKPENILFKN--CSKNSIQNSDIKIIDFGLA-TFIDKDEKKYMFQKCGTPGYVAPEVLNNKEVLKHKQYDTK

CDIWSIGVIMFILLCGEPPFLANSEEKLYELIKKGELRFENPV-WESVSDSAKNTLKQLMKVDPAHRITAKELLDNQWL
||.||.|||..|||||.||| . ...   ...|| .. |. |. || .|...|. .|.. ..|| .||||...|...| 
CDMWSCGVIFYILLCGKPPFKGKTYNEILQQNKKCKIDFNCPECWEKCSKECKDLMKKMLEKDPKKRITAQQALNHPWF
Kinase STK33.AA S_TKc 111-377 31 5.9e-102 345.94 SMART 1-231 (231) Show / Hide 
Range on Protein: 111-377
Range on HMM: 1-231/231
Sequence Identity: 31% (90 aa)

YTFGRILGQGSFGMVFEAIDKETGAKWAIKKVNKEKAGSSAMKLLEREVSILKTVNHQHIIHLEQVFESPQKMYLVMELCED--GELKAVMDQRGH----
|...|..|.|.|| |. ...|.|| . |||...         . ..||..|||  .| .|..|  ||.. ...|.|||.|.   |.|. ....||.    
YEILRKIGKGAFGKVYKCRHKKTGRIVAIKIIK---------EHIRREIQILKK-HHPNIVKLYDVFQD-DHLYMVMEYCDGDLGDLFDYIKKRGRHGLR

--FSENETRLIIQSLASAIAYLHNKDIVHRDLKLENIMVKSSFIDDNNEMNLNIKVTDFGLSVQKHGSRSEGMMQTTCGTPIYMAPEVINAHDYSQ-QCD
  |.| ..| ... ...|..|.|.. |.||||| |||.. .           .||..||||. |           | |||| ||||||.    |.   ||
FPFPE-HARFYMYQICCALEYCHSHGIIHRDLKPENILLDE-----------HIKICDFGLARQL---------TTFCGTPWYMAPEVL---GYGKCKCD

IWSIGVIMFILLCGEPPFLANSEEKLYELIKKGELRFENPVWESVSDSAKNTLKQLMKVDPAHRITAKELLD-------NQWL
.||.|.|....|||.|||    .......|.              |..||. .......||..|.|| |.|         .|.
WWSCGCILYEMLCGYPPFP--QMQMMFKKIG--------------SPEAKDFIRKCLQKDPEKRPTA-EALQDEWDIKCHPWF
Kinase STK33.AA RAD53 111-377 34 3.6e-100 299.1 In-house 1-305 (305) Show / Hide 
Range on Protein: 111-377
Range on HMM: 1-305/305
Sequence Identity: 34% (107 aa)

YTFGRILGQGSFGMVFEAIDKETGAKWAIKKVNKEK-A---GSS--AMKLLEREVSILKTVNHQHIIHLEQVFESP-QKMYLVMELCEDGEL-KAVMDQR
| ....||.| || | .|..|.|. | ||| ..| | .   ...   |. ...|| ||| .||. || .. .|..| .  |.|.|| ..|||   . .. 
YYMSKELGSGNFGTVKLAYEKKTCQKVAIKIIDKKKFFIRCMHTIKKMDQVMNEVEILKKLNHPCIIRIYDIFDTPQKYYYMVLELMTGGELFNKIVSNK

GH---FSENETRLIIQSLASAIAYLHNKDIVHRDLKLENIMVKSSFID---------DNNEMNLNIKVTDFGLSVQKHGSRSEG-MMQTTCGTPIYMAPE
.    |.|.. ...   .  |. |||.. |.||||| |||  ..   .         |  |... ||.||||||   .    || .|.| |||| | |||
RCQMGFDEDTCKYYFYQMCDAVKYLHDNGICHRDLKPENILCNHQDEECPQVQLGPWDEDEISFLIKITDFGLSKFVG----EGSFMKTMCGTPQYVAPE

VINAH---------------DYSQQCDIWSIGVIMFILLCGEPPFLAN-----SEEKLYELIKK-GELRFENPVWESVSDSAKNTLKQLMKVDPAHRITA
||                   |.  .|.||.|.| .|.||| |||        .. .|.| ||. | ..|. |.| ..|..||.  |.. .||| .|.|.
VITSKGHNCYHENEERQVQVGYTKKVDCWSMGCILYICLCGYPPFSDDYTQEMHCMQLFEQIKNQGKYHFPHPYWDRISEEAKDLIKWMLCVDPEKRYTI

KELLDNQWL
.|.|  .|.
DEALNHPWM
Kinase STK33.AA CAMKL 111-377 31 6.3e-98 313.11 In-house 1-297 (297) Show / Hide 
Range on Protein: 111-377
Range on HMM: 1-297/297
Sequence Identity: 31% (96 aa)

YTFGRILGQGSFGMVFEAID-KETGAKWAIKKVNKEKAGSSAMKL-------------LEREVSILKTVN---HQHIIHLEQVFESPQK------MYLVM
|..|. ||.|||| |  |.. . || | ||| ..|.|.     ..             ..||..|.| .|   |..||.| .|.| |..      .||||
YRIGKTLGKGSFGKVKLATHIRTTGEKVAIKIIDKKKIWNDPWMKKNKCGQKHESDMRIRREIQIMKMLNIGKHPNIIKLYEVIETPEHDIETKKIYLVM

ELCEDGE--LKAVMDQRGH----FSENETRLIIQSLASAIAYLHNKDIVHRDLKLENIMVKSSFIDDNNEMNLNIKVTDFGLSVQKH-G-SRSEGMMQTT
|.|. ||  |    ...||    ..|.|.| . . . ||..|.|...|||||.|.|||.. ..          |||..|||.| .   .   .. .. | 
EYCSGGEMDLFDYIVKHGHRRGRMPEHEARRYFRQIVSAVNYCHSHGIVHRDIKPENILLDENGNN-------NIKIIDFGFSNMYRPCIFGPGQKLKTF

CGTPIYMAPEVINA-HD-YS-QQCDIWSIGVIMFILLCGEPPFLANSE------EKLYELIKKGELRFENPVWESVSDSAKNTLKQLMKVDPAHRITAKE
||.| |||||...  .. |  .. ||||.|||.. ..||. || . .        . |.. |. .. .. |.| .|| .... ......|.| .|.|...
CGSPPYMAPEIFQGNNKPYDGPKVDIWSCGVILYAMVCGYLPFDDDTYNKQGKDNI-YLYWKIMCG-YYPPIWYHVS-DCRDLIRKMLQVNPEKRPTIHQ

LLDNQWL
..   |.
IMNHPWM
Kinase STK33.AA Pkinase 111-377 32 1.6e-92 318.51 Pfam 1-293 (293) Show / Hide 
Range on Protein: 111-377
Range on HMM: 1-293/293
Sequence Identity: 32% (99 aa)

YTFGRILGQGSFGMVFEAIDKETGAKWAIKKVNKEKAGSSAMKLLER--EVSILKTVNHQHIIHLEQVFESPQKMYLVMELCEDG----ELKAVMD--QR
|..||..|.|||| |.....| || ..|.|...|... |.  . . |  |..|.| .|| .|. |  .||.....|.|||.|| |    .|....   ..
YHIGRKIGSGSFGCVYKCHHKGTGKIVAVKIIKKRHEKSWKDQTHRRLSEIQIMKRLNHPNIVRLYDWFEDKDHIYMVMEYCEGGLYVMDLFDYISTWRH

GHF--SENETRLIIQSLASAIAYLHNKDIVHRDLKLENIMVK-SSFIDDNNEMNLNIKVTDFGLSVQKHGSRSEGMMQTTCGTPIYMAPEVIN-AHDYSQ
| |  ||.| . ..  ......|.|.. |.|||||.|||...    ||.       .|..||||. |.    . . |.| |||| |||||||. . .|..
GCFYFSEWECKFYMYQILRGLEYCHSMGIIHRDLKPENILIDNNGHIDA------CVKICDFGLAKQFD-Y-NNS-MTTFCGTPWYMAPEVIRGGQYYGP

QCDIWSIGVIMFILLCGEPPFLAN------SEEKLYELIKKGELRFENPVWESVS-----------------DSAKNTLKQLMKVDPAHRITAKELLDNQ
 .|.||.|.|....|||.|||         .. .....|....|.|. | | |.|                 ...|  .| . ..||. |.||...|   
KVDMWSCGCILYEMLCGRPPFPGHCWHDNHDQMQMICRIMGPPLHFDWPWWCSISYFFFRHWHFHWTFHNWSEECKDFIKWCLCKDPKKRPTAEQILQHP

WL
|.
WF
Kinase STK33.AA CDPK 111-377 37 2.9e-92 283.29 In-house 1-271 (271) Show / Hide 
Range on Protein: 111-377
Range on HMM: 1-271/271
Sequence Identity: 37% (102 aa)

YTFGRILGQGSFGMVFEAIDK-ETGAKW-AIKKVNKEKAGSSAM-KLLEREVSILKTVNHQHIIHLEQVFESPQKMYLVME--LCEDGELKAVMDQRGHF
|.....||.|.||.|. ...|  |. .  |.| ..| .   .   . . .|. |||.  | .|| .  ...  .  |.|||  .|. |||  .  ..|||
YKIKKVLGKGHFGQVRKVKHKQKTNQERVAMKIIPKSRVKDKEQQQQFFNEIEILKQLDHPNIIKIYEFYQDEKNYYIVMETEYCTGGELFDYIIEKGHF

SENETRLIIQSLASAIAYLHNKDIVHRDLKLENIMVKSSFIDDNNEMNLNIKVTDFGLSVQKHGSRS--EGMMQTTCGTPIYMAPEVINAHDYSQQCDIW
.| |...|.. . ||..| |.. ||||||| |||. .|   ||..    |||| |.|.| .  .. .  .  | . |||| |.||||..   | ..||||
TEKEAAYIMRQILSAVNYCHSNNIVHRDLKPENILFDSK-KDDSWV-IYNIKVIDWGTSKKFDQNQKIEDKKMSQRCGTPYYIAPEVLQKK-YNEKCDIW

SIGVIMFILLCGEPPFLANSEEKLYELIKKGELRFENPVWESVSDSAKNTLKQLMKVDPAHRITAKELLDNQWL
|.|||..|||||.||| . .... .| .|||. .|| | |...||.||.  ...  .||  |..| . |. .| 
SCGVILYILLCGYPPFYGKNDQEIMEKVKKGKYSFEGPEWDHISDEAKDLIRKMLCYDPKKRMSAQQALQHPWF
Kinase STK33.AA Ciliate-E2 111-377 23 1.1e-89 304.25 In-house 1-365 (365) Show / Hide 
Range on Protein: 111-377
Range on HMM: 1-365/365
Sequence Identity: 23% (90 aa)

YTFGRILGQGSFGMVFEAIDKETGA------------------KWAIKKVNKEKAGSSAMKLLEREVSILK----------------TVNHQHIIHLEQV
| | ...|||.|| |... .....                   | .||.....    .  . ...| .|..                ..|| .|| .  .
YKFIKKIGQGNFGSVYKCKVWKVQKQFAIKIIDQKQQRQQMQEKVKIKIYAMKIMKKNQIEQIKQEIHIMREINCFYKKINEKNILEQLNHPNIIKMYEC

FE--SPQKMYLVMELCEDGELKAVMDQRGHFS-----------ENETRLIIQSLAS---------------AIAYLHNKD-IVHRDLKLENIMVKSSFID
|.  . ...|||||.|. |.|.  . .. ...           |.| . |.. ...               |. |||.|  |.|||.|.|||..      
FQEKDDNNIYLVMEYCQGGDLFDYIKNNKKKRNHEIEKDKYFTEKEIKYIMKQILQGFKTKAEFYIACIILALEYLHSKNNIIHRDIKPENILF------

DNNEMNLNIKVTDFGLSVQKHGSRSEG-----------------------------MMQTTCGTPIYMAPEVIN---------AHDYSQQCDIWSIGVIM
        ||..||||| . . .. ..                             | .|.|||| |||||..|          ..|. .|||||.|||.
--------IKIIDFGLSKKYDDDNQNRTHKQQCKWYMFKNDTSRTPGYMDQIIQQNMFNTICGTPGYMAPEILNGKKYDNQQKQKGYDYKCDIWSLGVIL

FILLCGEPPFLANSEEKLYELIKKGELRFENP--------------VWESVSDSAKNTLKQ----LMKVDPAHRIT-AKELLDNQWL
...|.|.|||        .. ||.....| .|               |...|...|. .|.    ....||  ||| ....|...|.
YEMLFGKPPF--------QQQIKQCKIDFPCPEWQKDTQCIQCKWKSWKKWSQECKDLIKKFGKRMLQKDPEKRITGWEQILNHPWF
Kinase STK33.AA Ciliate-E2-Unclassified 111-377 26 1.8e-85 290.23 In-house 1-352 (352) Show / Hide 
Range on Protein: 111-377
Range on HMM: 1-352/352
Sequence Identity: 26% (94 aa)

YTFGRILGQGSFGMVFEAIDKETG--------AKWAIKKVNKEKAGSSAMKLLEREVS----------------ILKTVNHQHIIHLEQVFESPQKMYLV
|......|||.|| |.....|...         |  |.|... .     ... . |.                 ||.  .| .|.... .|.. |..|.|
YKIIKQIGQGGFGKVYKCQHKKQKQYYAMKYMKKIQIYKQKQIMNKD-EIMNEMKEMNNKKKYHQRKYNKIMQQILLNHPHPFIVKMFYCFQDKQNIYIV

MELCEDGELKAVMDQRGH-----------------FSENETR-----LIIQSLASAIAYLHNKD-IVHRDLKLENIMVKSSFIDDNNEMNLNIKVTDFGL
||.||.|.|.  . .|..                 |.|....      ..  . ... ||| |  |.|||.|.|||.....        |..||..|||.
MEYCEGGDLWQYIKKRKKQKQKGNDLFHNMKQRKIFTEQQAKYKKAKFYFAQILQGLEYLHHKNNIIHRDIKPENILFDNNGK------NYYIKIIDFGI

SV-------------QKHGSRSEGMMQTTCGTPIYM----APEVINAHDYSQQ----CDIWSIGVIMFILLCGEPPFLANSEEK----------------
|              || .  .. ||.|.||||.||    ||||.  . |...    ||||| |||.. .| |..|| .|..|.                
SKKYQQNNNCDTNQQQKMQIWKQQMMWTFCGTPNYMPQYTAPEVLQGQNYDHSKAYKCDIWSLGVILYEMLFGYYPFYDNNCEQHQQLITQWINNAYRKQ

LYELIKKGELRFENPVW----ESVSDSAKNTLK----QLMKVDPAHRITAKELLDNQWL
||. ||.... | .  |      .|..||. ..    ...|..|  |||....|  .|.
LYQNIKQKNIQFPKFPWQQIPKHWSPEAKDFINDLLQKMLKKNPNKRITFEQILNHPWF
Kinase STK33.AA MARK 111-377 35 1.2e-84 276.65 In-house 1-262 (262) Show / Hide 
Range on Protein: 111-377
Range on HMM: 1-262/262
Sequence Identity: 35% (97 aa)

YTFGRILGQGSFGMVFEAIDKETGAKWAIKKVNKEKAGS-SAMKLLEREVSILKTVNHQHIIHLEQVFE--SPQK-MYLVMELCEDGELKAVMDQR--GH
| ... .|.||.. |  |..| || | ||| ..|.|     .|| ..||..|.| ..| .|| | .|.|   .|.  ||.||... |||   . ..  |.
YKMLKTIGHGSYAKVKLACHKHTGRKVAIKIYEKFKLNDPQWMKNVMREIEIMKKLDHPNIIKLFHVIEQDTEQHQIYLIMEYASGGELYDYIKAHPNGR

FSENETRLIIQSLASAIAYLHNKDIVHRDLKLENIMVKSSFIDDNNEMNLNIKVTDFGLSVQKHGSRSEGMMQTTCGTPIYMAPEVINAHDYS-QQCDIW
 .|.|.| | . . ||. |.|.|.|||||.|.|||..         ..| ||| .|||.|..     .. .  | |||| |||||...  .|  .  |||
LHEEEARRIFRQIVSAVNYCHSKNIVHRDIKPENILI-------DENGNHNIKIIDFGFSIC---IPPGQKLNTFCGTPPYMAPEIFLKKPYDGPKVDIW

SIGVIMFILLCGEPPFLANS--EEKLYELIKKGELRFENPVWESVSDSAKNTLKQLMKVDPAHRITAKELLDNQWL
| ||......||  || . .  ...||. | .|. ..       ||....| ...|..|.|  |.|..|..   |.
SLGVVLYFMVCGYFPFDGDTQDYKELYKKILRGKYDIPCH----VSKECRNLIQRLLTVNPEERPTIEEIMKHPWM
Kinase STK33.AA Pkinase_Tyr 111-335 28 4.5e-33 112.63 Pfam 1-233 (270) Show / Hide 
Range on Protein: 111-335
Range on HMM: 1-233/270
Sequence Identity: 28% (69 aa)

YTFGRILGQGSFGMVFEAIDK----ETGAKWAIKKVNKEKAGSSA--MKLLEREVSILKTV-NHQHIIHLEQVFE-SPQK--MYLVMELCEDGELKAVMD
 |||. ||.|.||.|.... |    .|. . |.|.. ||.| ...  .. . ||..|.|.  .|..|. |  |     .   .|.|||... | |.    
ITFGKKLGEGAFGEVYKGTWKGDPDNTKIPVAVKML-KEGAMHEQNCREDFMREAKIMKQLGHHPNIVRLYGVCTDQGEPNQIYIVMEYMPHGDLLDYLR

Q----RGHFSENETRLIIQSLASAIAYLHNKDIVHRDLKLENIMVKSSFIDDNNEMNLNIKVTDFGLSVQKHGSRSEG-MMQTTCGTPI-YMAPEVINAH
.    .....  .   . .  |.. .||..| ..||||   |..|..         |. .|..||||.     . ..   ... .  ||  ||||.||  
KHREDKQPLTMKDLLQMCWQIAKGMEYLESKNCIHRDLAARNCLVTE---------NNVVKICDFGLARDI-YNDDYYYRKRGGGKLPIKWMAPECINYG

DYSQQCDIWSIGVIMFILLC-GEPP-FLANSEEKLYELI-KKGE
 .. . |.|| || |. ..  || | .   | | .||.| ..|.
KFTTKSDVWSFGVLMWEIFTYGEQPTYPGMSNEEVYEYIYEDGY
Kinase STK33.AA TyrKc 111-377 24 9.1e-25 89.52 SMART 1-280 (280) Show / Hide 
Range on Protein: 111-377
Range on HMM: 1-280/280
Sequence Identity: 24% (72 aa)

YTFGRILGQGSFGMVFEAIDKETGAKWAIKKVNKEKAGSSAMKLLEREVSILKTV--NHQHIIHLEQVFESP-------QKMYLVMELCEDGELKAVM-D
 |.|..|| | || |.... |    . |.|......     .. . || .|.. .  .|..|. |  |  ..       . ...|||... | ||    .
ITLGKKLGEGAFGEVYKGTWK---IQVAVKMLKEDA-----REDFMREARIMCKLGGHHPNIVRLYGVCTQQGRNFMYIEPLMIVMEYMPHGDLKDYLRK

QRGHFSENETRLIIQSLASAIAYLHNKDIVHRDLKLENIMVKSSFIDDNNEMNLNIKVTDFGLSVQKHGS-----RSEGMMQTT--CGT---PI-YMAPE
 |....  .   .    |.  .||| | ..||||   |..|.. .          .|..|||||   .       ...  ....  .|    ||  ||||
HRPKLCMKDLLSFCWQIACGMEYLHSKNCIHRDLAARNCLVGENH---------TVKISDFGLSRDIYDDDQQGESKDYYRKKEHKGGKTMLPIRWMAPE

VINAHDYSQQCDIWSIGVIMF-ILLCGEPPFLA-----NSEEKLYELIKKGELRFENPVWE------SVSDSAKNTLKQLMKVDPAHRITAKELLDNQWL
.|| . .. . |.|| || |. |.  |..|         | . ..|..|.|. .   |  .        ..  .   ||  . ||. | | .|.   . .
CINYGKFTTKSDVWSFGVCMWEIFTYGQQPYPGMIQQMMSNQEVIEYVKQGYRMPQPPNDYPMSFVCCPDEMYQ-IMKQCWHEDPEDRPTFSEI--HECF