Gene TNK1 (Mouse)

TNK1

Species: Mouse
Alias: TNK1, Tnk1
External Links: MGI , Entrez Gene , Refseq cDNA , Refseq Protein , Phosphosite , iHOP
Annotation:

Classification

Group: TK
Family: Ack

Sequence

Name Sequence Type Origin Length Description Download
TNK1.AA Protein Sugen 666 None Fasta, JSON
TNK1.NA RNA Sugen 2668 None Fasta, JSON
TNK1.kin_dom Protein Kinase Domain Sugen global kinase HMM prediction 263 Kinase domain by global Sugen HMM Fasta, JSON

Protein domain

Protein domains of TNK1.AA. The domains are annotated by HMM profiles from Pfam and SMART, as well as in-house data which includes HMMs of each individual kinase group, family and subfamily. Here is domain list in details, including sequence identity, significance and alignment. In particular, you can find can find the best hit kinase group/family/subfamily, which is helpful to understand the relationship between kinases.Kinase domain and best hit kinase group/family/subfamily are highlighted in red and blue. Visualized by pviz.

Usage: Zoom in selected region by dragging mouse and zoom out by double-clicking.

Show/hide domain list
Domain Protein name Domain Name Range Identity (%) Significance Score Profile Source Profile Range (length) Alignment
SAM_Ack TNK1.AA SAM_Ack 5-69 49 1.7e-27 95.23 In-house 1-65 (65) Show / Hide 
Range on Protein: 5-69
Range on HMM: 1-65/65
Sequence Identity: 49% (32 aa)

ASSLWLLRLLRDVQLAQFYRPILEELNVTRPEHFDFVRPEDLDNIGMGRPAQRRLNEALKRYRSG
 .  ||. .||..|| |.|. | ..|.|||..|||.|..|||. |||.||.|||| || |...  
EECQWLYEFLREAQLEQYYNQIRDHLKVTRLDHFDYVKDEDLECIGMSRPEQRRLWEAYKKMCPH
Sam7 TNK1.AA sam7 5-67 17 1.6e-08 28.18 In-house 1-70 (70) Show / Hide 
Range on Protein: 5-67
Range on HMM: 1-70/70
Sequence Identity: 17% (12 aa)

ASSLWLLRLLRDVQL---AQFYRPILEELN---VTRPEHFDFVRPEDLDNIGMGRPA-QRRLNEALKRYR
 .  ..   |.....    |..  .....    ||  .|.. .  |||  .|. ||  .... ..... |
WTFEDVCEWLEWIGMENFQQYCDNFRDHGIDDWVTDGDHLCHMTEEDLMEMGITRPGHRKKIWNHIQQMR
Kinase TNK1.AA Ack 116-378 51 4.7e-177 594.49 In-house 1-266 (266) Show / Hide 
Range on Protein: 116-378
Range on HMM: 1-266/266
Sequence Identity: 51% (137 aa)

VRRGELLGSGCFGVVHRGLWTLPSGQSIPVAVKSLRVGPEGPMGTELGDFLREVSVMMKLEHPHVLRLHGLVLGQPL-QMVMELAPLGSLHARLTAPAPT
....|.||.||||||.||.||.|.|..|.||||.||.. .........||||||..|..|.|||..||.|.||.||. .||.||||.|||. .|.....|
ITLCEKLGDGCFGVVWRGEWTNPGGKHIQVAVKCLRSD-KMQQPNCMDDFLREVAIMHSLDHPHLVRLYGVVLDQPMLMMVTELAPCGSLLDCLRKHCRT

PPLPVALLCLFLRQLAGAMAYLGSCGLVHRDLATRNLLLASP-RMIKVADFGLVRPLGGARGRYVMGGPR--PIPYAWCAPESLRQGAFSSASDVWMFGV
.......|| |..|.|..|.||......|||||.||.||.|. |..|..||||.|.||.....|.|...|  ..|.||||||.||...||.|||||||||
AFFLIHTLCDFCMQIAMGMRYLEMKRCIHRDLAARNILLFSDDRKVKICDFGLMRALGQNEDYYRMEFHRNLKVPFAWCAPECLRHRQFSHASDVWMFGV

TLWEMFSGGEEPWAGVPPYLILQRLEKDRARLPKPPLCSRALYSLALRCWAPHPADRPSFSNLEGLL
|||||||.|||||||...|.|||...|...|||.|..|....|.....||..||||||.||.....|
TLWEMFSYGEEPWAGCNGYQILQKIDKEGERLPRPDCCPEDIYQMMMQCWQHHPADRPTFSAIRDQL
Kinase TNK1.AA Pkinase_Tyr 116-378 37 4.7e-114 386.89 Pfam 1-270 (270) Show / Hide 
Range on Protein: 116-378
Range on HMM: 1-270/270
Sequence Identity: 37% (102 aa)

VRRGELLGSGCFGVVHRGLWT-LPSGQSIPVAVKSLRVGPEGPMGTE--LGDFLREVSVMMKL-EHPHVLRLHGLVL--GQP--LQMVMELAPLGSLHAR
.. |. ||.|.||.|..| |. .|... ||||||.|.   || |  .  . ||.||...|..|  ||...||.| ..  |.|  . .|||..|.|.|.  
ITFGKKLGEGAFGEVYKGTWKGDPDNTKIPVAVKMLK---EGAMHEQNCREDFMREAKIMKQLGHHPNIVRLYGVCTDQGEPNQIYIVMEYMPHGDLLDY

LTAP-APTPPLPVALLCLFLRQLAGAMAYLGSCGLVHRDLATRNLLLASPRMIKVADFGLVRPLGGARGRY-VMGGPRPIPYAWCAPESLRQGAFSSASD
| ..  . .||..  |. . .| | .|.|| | ...|||||.|| |..... .|..|||| | .    . | ...|  ..|  |.|||... | |...||
LRKHREDKQPLTMKDLLQMCWQIAKGMEYLESKNCIHRDLAARNCLVTENNVVKICDFGLARDI-YNDDYYYRKRGGGKLPIKWMAPECINYGKFTTKSD

VWMFGVTLWEMFSGGEEP-WAGVPPYLILQRLEKDRARLPKPPLCSRALYSLALRCWAPHPADRPSFSNLEGLL
||.|||..||.|. ||.| ..|.... ..... .|. |.|.|..|.  .|.| ..||.. |.|||.|| .   |
VWSFGVLMWEIFTYGEQPTYPGMSNEEVYEYIYEDGYRMPCPENCPDEIYDLMKQCWHYDPEDRPTFSEIHEQL
Kinase TNK1.AA TyrKc 116-378 32 3.7e-111 376.5 SMART 1-280 (280) Show / Hide 
Range on Protein: 116-378
Range on HMM: 1-280/280
Sequence Identity: 32% (97 aa)

VRRGELLGSGCFGVVHRGLWTLPSGQSIPVAVKSLRVGPEGPMGTELGDFLREVSVMMKL--EHPHVLRLHGLVLG--------QPLQMVMELAPLGSLH
.. |. ||.|.||.|..| |.      |.||||.|. .        . ||.|| ..|.||  .||...||.| ..         .|| .|||..|.|.|.
ITLGKKLGEGAFGEVYKGTWK------IQVAVKMLKEDA-------REDFMREARIMCKLGGHHPNIVRLYGVCTQQGRNFMYIEPLMIVMEYMPHGDLK

ARLTAPAPTPPLPVALLCLFLRQLAGAMAYLGSCGLVHRDLATRNLLLASPRMIKVADFGLVRPLGGA-----RGRYVM-----GGPRPIPYAWCAPESL
 .| .. |.  |... |. |  | |  |.|| | ...|||||.|| |..... .|..|||| | ..       .. | .     ||  ..|. |.|||..
DYLRKHRPK--LCMKDLLSFCWQIACGMEYLHSKNCIHRDLAARNCLVGENHTVKISDFGLSRDIYDDDQQGESKDYYRKKEHKGGKTMLPIRWMAPECI

RQGAFSSASDVWMFGVTLWEMFSGGEEPWAG-----VPPYLILQRLEKDRARLPKPPL--------CSRALYSLALRCWAPHPADRPSFSNLEGLL
. | |...||||.|||..||.|. |..|. |     .... ....... . |.|.||         |. ..|.. ..||.  |.|||.||..  ..
NYGKFTTKSDVWSFGVCMWEIFTYGQQPYPGMIQQMMSNQEVIEYVKQGY-RMPQPPNDYPMSFVCCPDEMYQIMKQCWHEDPEDRPTFSEIHECF
Kinase TNK1.AA TK 116-378 20 3.2e-94 316.27 In-house 1-486 (486) Show / Hide 
Range on Protein: 116-378
Range on HMM: 1-486/486
Sequence Identity: 20% (101 aa)

VRRGELLGSGCFG---VVHRGLWTL----------------------PSGQSIPVAVKSLRVGPEGPMGTELG----------DFLREVSVMMKLE----
.. |. ||.| ||   .|..|.|                        ..|. .||||| |. | .  .  ..           |||.|...|...     
ITLGKKLGEGQFGSFGEVYKGEWRGRNPWNGKRFPCHMTVTLKCKNGKEGGKTPVAVKMLKEGDAMSQEEFFDEEMHDRDGGEDFLEEAEEMKMMCHSLG

-HPHVLRLHGLVLGQ-------------PLQMVMELAPLGS----LHARLTAPAPTPP------------------------------------------
 ||...||.| .. .             |. .|||..|.|.    |.  | .  |.                                            
HHPNIVRLYGVCTQGEPKPCFEVVVHQEPWMIVMEYMPHGDMDGSLRDYLRKCRPKFQHEQDCPDNQHNKYPPSKLHHCMKGDITYSHESNSPCPEEQDY

-------------------------------LPVALLCLFLRQLAGAMAYLGSC------GLVHRDLATRNLLLASPRM-----------IKVADFG---
                               |... |. . .|.| .|.|| |.      ..||||||.|| |...              .|.||||   
DDDLIKDHPPPLTTKDLLQMAWQWCLTCKHQLTMHQLL-MCWQIACGMEYLHSKNCEFIQNFVHRDLAARNCLVGENNVCKWHFDGCGPVCKIADFGLSR

-----LVRPLGGARGRYVMGGPR-----------------------PIPYAWCAPESLRQGA---------FSSASDVWMFGVTLWEMFSGGEEPWAG-V
     | | ..     |......                        .|  |.|||.|. .          |...||||.|||..||.|. |.||..| .
QGSGVLARDIYSDDDYYRKSSYGTGRPMWPFEDDPWQDYYRQQSGGKLPIRWMAPECLNDRVFSEAEKYGKFTTKSDVWSFGVLMWEIFTYGQEPYYGGM

PP---------YLILQRLEKD-------------RARLPKPPLCS--------------RALYSLALRCWAPHPADRPSFSNLEGLL
.            ....|..              | |.|.||.|.               ..| | ..||.. |.|||.|| |   |
SNQDVWKDGDNQEVMEYLRRGGRLCRSGLNEVGYRMRMPQPPHCPDWMRYRMHPPHCPPEEYYDLMQQCWHYDPEDRPTFSQLHEQL
Kinase TNK1.AA UTK 116-378 31 1.7e-77 263.73 In-house 1-296 (296) Show / Hide 
Range on Protein: 116-378
Range on HMM: 1-296/296
Sequence Identity: 31% (95 aa)

VRRGELLGSGCFGVVHRGLWTLPS--GQSIPVAVKSLRVGPEGPMGTELGD----FLREVS---VMMKLE-HPHVLRLHGLVL-GQPLQMVMELAPLGSL
|..|..||.| ||.||.. .| .|  ..   |||| ..   .. ...   .    |..|     .|.... ||.|||| |... ..|. .|.|... |.|
VQLGRQLGQGAFGEVHKARFTQCSEHMYEMDVAVKVCQ---HHADAQQEPEPYPDFMEEARELQMMKQFHWHPNVLRLVGVCTQEEPWMIVTEYMENGDL

HARLTAPAPTPP-----LPVALLCLFLRQLAGAMAYLGSCGLVHRDLATRNLLLASPR-------MIKVADFG---LVRPLGG--------ARGRYVMGG
 . |   .||||     |    .  . .. | .|.|| |||.|||||| || |... |        .|.||||   . | ...            | . .
RSYLRRHRPTPPACPHWLTLHQRLCMAWDIARGMQYLHSCGFVHRDLAARNCLVHMHRMMWHCMMVCKIADFGRGGMSRRVNTFHFSNRYWESYYYMAQH

PRPIPYAWCAPESLRQG-AFSSASDVWMFGVTLWEMFSGGEEPWAGV-PPYLILQRLEKDRARLPKPPLCSRALYSLALRCWAPHPADRPSFSNLEGLL
 ...| .|.|||.| ..  |...|||| |||..||....|  |..|   . ...| ....|.|.|.|. |....| | .|||.. |..||.|  |.  .
QDRWPIRWMAPEALTHHTRFTTKSDVWSFGVVCWEIWTWGRLPYPGMSNMQVWHQVCNGGRYRMPCPWDCPHPVYRLMHRCWHYDPQERPDFEDLVQQM
Kinase TNK1.AA TK-Unique 116-378 32 2.7e-66 226.56 In-house 1-294 (294) Show / Hide 
Range on Protein: 116-378
Range on HMM: 1-294/294
Sequence Identity: 32% (96 aa)

VRRGELLGSGCFGVVHRGLWTLPS---GQSIPVAVKSLRVGPEGPMGTELGDFLREVSVMMKLE-HPHVLRLHGLVL--GQPLQMVMELAPLGSLHARLT
.. |...|.| || |.||  . ..   .. . |||| |.   ..  .|.  |||.| ..|..|  ||..... |     ..| ...|| .| |.|   | 
LEVGDVIGEGAFGQVWRGEVWGIWKHWDKQKCVAVKMLK---DNATDTDKQDFLKEIQMMKELGDHPNIVQCLGCCTKSDEPWMIIMEYCPCGNLQHYLR

APAPT--PP---------------------LPVALLCLFLRQLAGAMAYLGS--CGLVHRDLATRNLLLASPRMIKVADFGLVRPLGGARGRYVMG-GPR
  .|.  ..                     .   .|  |. |.| .|.|| |  .. |||||..|| ||..  ..|..|||. | .   .| |.|  .  
TCRPAMRQHQTYGNLKFDFHHMPDKPRTEPISPKDLYHFAWQIACGMEYLASQRKKIVHRDLCARNVLLTEDKVCKICDFGMARDVYT-NGVYSMMCSQG

PIPYAWCAPESLR--QGAF-SSASDVWMFGVTLWEMFSGGEEPWAGVPPYLILQRLEKDRARLPKPPLC-SRALYSLALRCWAPHPADRPSFSNLEGLL
.||..|.|||||.  .| . .. ||||.|||..||.|. |. |  |.|.  |.... .|  |.|.|. | |...|.|  .||   | .||||. .   |
RIPIRWMAPESLKCYHGMYHTTKSDVWSFGVLMWEIFTLGACPYPGMPWKDIMECI-RDGYRMPQPEHCCSHEMYNLMKSCWQWEPEERPSFRQIKHRL
Kinase TNK1.AA EGFR 116-379 34 1.8e-63 209.51 In-house 1-258 (258) Show / Hide 
Range on Protein: 116-379
Range on HMM: 1-258/258
Sequence Identity: 34% (93 aa)

VRRGELLGSGCFGVVHRGLWTLPSGQS--IPVAVKSLRVGPEGPMGTELGDFLREVSVMMKLEHPHVLRLHGLVLGQPLQMVMELAPLGSLHARLTAPAP
....  |||| || |..|.|  | |..  ||||.| ||   |        ..|.|  ||  ..|||..|| |. ... .|.|  . |.|.|   .     
LKKVKVLGSGAFGTVYKGIW-IPEGENVKIPVAIKVLR---EQTGPKANEEMLDEAYVMASVDHPHLVRLLGVCMHSQMQLVTQYMPYGCLLDYVRQHKD

TPPLPVALLCLFLRQLAGAMAYLGSCGLVHRDLATRNLLLASPRMIKVADFGLVRPLGGARGRYVMGGPRPIPYAWCAPESLRQGAFSSASDVWMFGVTL
.  .   .| ..  | |  | ||    .||||||.|| |. ||  .|..|||| . |      | . | . .|  | | |..... . ..|||| .|||.
N--IGSQHLLNWCVQIAKGMQYLEEHRMVHRDLAARNVLVKSPNHVKITDFGLAKLLEHDEKEYHAQGGK-MPIKWMALECIHHRCYTHQSDVWSYGVTC

WEMFSGGEEPWAGVPPYLILQRLEKDRARLPKPPLCSRALYSLALRCWAPHPADRPSFSNLEGLLQ
||.   |..|..|.|   | . |||   ||| || |.  .| . ..||   .. || |  |   ..
WELMTFGQKPYDGIPAREIPDLLEKG-ERLPQPPICTIDVYMVMVKCWMIDEDMRPTFKELYEEFK
Kinase TNK1.AA FAK 116-383 33 3.2e-62 207.21 In-house 1-285 (285) Show / Hide 
Range on Protein: 116-383
Range on HMM: 1-285/285
Sequence Identity: 33% (98 aa)

VRRGELLGSGCFGVVHRGLWTLPSG------------------------QSIPVAVKSLRVGPEGPMGTELGDFLREVSVMMKLEHPHVLRLHGLVLGQP
.  .  .| | || |. | .|.. .                        . | ||.|  .   . .  .|   |. |  .| .. |||. .| |..  .|
ITLNRCIGEGQFGDVYQGVYTNHKNGKGKNLAGNGKNSNSDQRNADSRPDKIQVAIKTCKKCCD-DDNKE--KFMQEAYIMKQFDHPHIVKLIGICEEMP

LQMVMELAPLGSLHARLTAPAPTPPLPVALLCLFLRQLAGAMAYLGSCGLVHRDLATRNLLLASPRMIKVADFGLVRPLGGARGRYVMGG-PRPIPYAWC
  ..|||...| | . | .      | .| | |.  ||. ||||| |   |||| | ||.| .||  .| .|||| | .      |         |  | 
IWIIMELCKYGELRHYLQRNKNS--LKHATLILYCYQLCMAMAYLESKKFVHRDIAARNVLVSSPDCVKLGDFGLSRWMHDH--SYYKASPKGKLPIKWM

APESLRQGAFSSASDVWMFGVTLWEMFSGGEEPWAGVPPYLILQRLEKDRARLPKPPLCSRALYSLALRCWAPHPADRPSFSNLEGLLQEAWL
.|||     | .||||||||| .||  . |  |  .|    .  |.|.   |||.||.|   ||||  ||||  | .|| | .|   |..  .
SPESINFRRFTTASDVWMFGVCMWEILMYGVKPFQWVKNNDVIGRIENG-ERLPMPPNCPPTLYSLMTRCWAYDPSKRPRFKELKCQLKDIYQ
Kinase TNK1.AA Syk 116-372 34 1.4e-55 189.78 In-house 1-257 (257) Show / Hide 
Range on Protein: 116-372
Range on HMM: 1-257/257
Sequence Identity: 34% (91 aa)

VRRGELLGSGCFGVVHRGLWTLP----SGQSIPVAVKSLRVGPEGPMGTELGDFLREVSVMMKLEHPHVLRLHGLVLGQPLQMVMELAPLGSLHARLTAP
. ... .|.| || || |          .| |.||.| |.   ..    .   |.|| .||..|.||.. |. |  .. .. ||||.|.||..|  |   
LVQDNEIGCGNFGSVHKGWYMMKSGAGEKQWIKVAIKMLKA--DHNQPADKQEFMREAQVMCQLDHPCIVRMIGICHAEMMMMVMEMAELGPMHKYLQQH

APTPPLPV-ALLCLFLRQLAGAMAYLGSCGLVHRDLATRNLLLASPRMIKVADFGLVRPLGGARGRYVM--GGPRPIPYAWCAPESLRQGAFSSASDVWM
      .. . | |   | |  | || .   |||||| || ||      |. |||. . ||     |.   .|  |.   | |||.   . ||..|||| 
RHE--ITANNVLELWHTQVAMGMCYLEEKHFVHRDLAARNVLLVNRHYAKISDFGMSKALGADSQYYQATTHGKWPV--KWYAPECIYYYKFSHKSDVWS

FGVTLWEMFSGGEEPWAGVPPYLILQRLEKDRARLPKPPLCSRALYSLALRCWAPHPADRPSFS
||||.||||| |  | ..     ... .|.   |...|..| . .|.|  .||   . ||| |.
FGVTMWEMFSYGQKPYGEMKGQEVMKFIENG-HRMNCPNGCPQEMYQLMNKCWIYKWCDRPTFV
Kinase TNK1.AA Src 116-378 35 2.5e-54 182.96 In-house 1-255 (255) Show / Hide 
Range on Protein: 116-378
Range on HMM: 1-255/255
Sequence Identity: 35% (93 aa)

VRRGELLGSGCFGVVHRGLWTLPSGQSIPVAVKSLRVGPEGPMGTELGDFLREVSVMMKLEHPHVLRLHGLVLGQ-PLQMVMELAPLGSLHARLTAPAPT
... . ||.|.|| |  |.|     ....||||.|. |    | .|  .||.|  .| || |.....|.  .    |   | |.   ||| . | .   .
IKLCRKLGQGQFGEVWMGYWN----GNTKVAVKTLKPGT---MSPE--AFLQEAQIMKKLRHEKLVQLYAVCSQEEPIYIVTEYMSHGSLLDYLKKDGEG

PPLPVALLCLFLRQLAGAMAYLGSCGLVHRDLATRNLLLASPRMIKVADFGLVRPLGGARGRYVMGGPRPIPYAWCAPESLRQGAFSSASDVWMFGVTLW
  |..  |  .  | |  ||||.|  ..||||| || |     . ||||||| | .      |..     .|. | ||| .. | |.  |||| ||. |.
RHLHLPQLIDMAAQVAEGMAYLESMNYIHRDLAARNVLVGENNVCKVADFGLARLIKEDDDEYCARHGAKFPIKWTAPEAINYGRFTIKSDVWSFGILLT

EMFSGGEEPWAGVPPYLILQRLEKDRARLPKPPLCSRALYS-LALRCWAPHPADRPSFSNLEGLL
|... |  |  |      ||..|.   |.|.|. |   ||  . |.||   | .|| |  |   |
EIVTYGRVPYPGMTNHEVLQQVERGY-RMPCPHNCPDELYEQIMLQCWHKDPEQRPTFEYLQWFL
Kinase TNK1.AA CTKA 145-378 37 8.9e-54 179.01 In-house 37-290 (290) Show / Hide 
Range on Protein: 145-378
Range on HMM: 37-290/290
Sequence Identity: 37% (97 aa)

VAVKSLRVGPEGPMGTELGD--FLREVSVMM--KLEHPHVLRLHGLVL-GQPLQMVMELAPLGSLHARLTAPAPTP-----------------PLPVALL
||||.|.       .||     || |. |    ...|| |||| |...  .|. |.||  ..| ||  |.| .| .                 |. |   
VAVKMLKD-----HATEEDRRAFLHEAFVLSSEHFHHPNVLRLLGVCTQHKPWHMIMEHMQYGDLHCYLRACRPADGQVCPARARRSIPRSFHPIEVHAH

--CLFLRQLAGAMAYLGSCGLVHRDLATRNLLLASPRMIKVADFGLVRPLGGARGRYVMGGPRPIPYAWCAPESLRQGAFSSASDVWMFGVTLWEMFSGG
      .| |  | || . |.|||||| || || .   ||.||||. | | .    |..   | .|  | ||| |. | ||.||||| ||| |||..|.|
EQVYMAMQIAAGMNYLAEMGFVHRDLACRNCLLGQYCHIKIADFGHGRTLRTESQYYYVSSQRVMPVRWMAPEALCFGKFSCASDVWAFGVLLWEIMSMG

EEPWAGVPPYLILQRLEKD-RARLPKPPLCSRALYSLALRCWAPHPADRPSFSNLEGLL
| ||..     . |        ||| |. |   ||..   || . |. ||.|  |   |
EKPWRHMSDQEVCQAYTSHGMRRLPVPRNCPQVLYHCMQECWKFEPNQRPTFETLQRML
Kinase TNK1.AA Eph 116-378 35 1.1e-53 178.65 In-house 1-264 (264) Show / Hide 
Range on Protein: 116-378
Range on HMM: 1-264/264
Sequence Identity: 35% (97 aa)

VRRGELLGSGCFGVVHRGLWTLP-SGQSI---PVAVKSLRVGPEGPMGTELGDFLREVSVMMKLEHPHVLRLHGLV-LGQPLQMVMELAPLGSLHARLTA
..  . .|.| || | .|   ||   . .   |||.| |..   | .  .  |||.| |.|   .||...|| | |  ..|.  | |   .||| . |  
IKIEKVIGAGEFGEVCCGRLKLPSGKREVWVDPVAIKTLKA---GYTEKQRWDFLSEASIMGQFDHPNIIRLEGVVTKSRPVMIVTEYMENGSLDSFLRQ

PAPTPPLPVALLCLFLRQLAGAMAYLGSCGLVHRDLATRNLLLASPRMIKVADFGLVRPLGGARG---RYVMGGPRPIPYAWCAPESLRQGAFSSASDVW
      . |. |   || .| .| || . . |||||| || |. |  . ||.|||| | |    .    |   | . ||  | ||| .  . |.||||||
HDG--QFTVIQLVGMLRGIASGMKYLSDMNYVHRDLAARNILVNSNLVCKVSDFGLSRVLEDDPSVEATYTTRGGK-IPIRWTAPEAIAYRKFTSASDVW

MFGVTLWEMFSGGEEPWAGVPPYLILQRLEKDRARLPKPPLCSRALYSLALRCWAPHPADRPSFSNLEGLL
 .|. .||  | || |    .   ...  |..  ||| |. | .||. |.| ||.  ...|| |...   |
SYGIVMWEVMSYGERPYWDMSNQDVIKAIEQG-YRLPPPMDCPEALHQLMLDCWQKDRNHRPHFQQIVSIL
Kinase TNK1.AA S_TKc 116-383 21 1.2e-44 155.61 SMART 1-231 (231) Show / Hide 
Range on Protein: 116-383
Range on HMM: 1-231/231
Sequence Identity: 21% (60 aa)

VRRGELLGSGCFGVVHRGLWTLPSGQSIPVAVKSLRVGPEGPMGTELGDFLREVSVMMKLEHPHVLRLHGLVLGQPLQMVMELAPL--GSLHARLTAPAP
 . ....|.| ||.|... ..        ||.| ..            ...||.....|  ||.. .|..    . | ||||...   |.|. ..    .
YEILRKIGKGAFGKVYKCRHKK---TGRIVAIKIIK-----------EHIRREIQILKK-HHPNIVKLYDVFQDDHLYMVMEYCDGDLGDLFDYIKKRGR

TPP---LPVALLCLFLRQLAGAMAYLGSCGLVHRDLATRNLLLASPRMIKVADFGLVRPLGGARGRYVMGGPRPIPYAWCAPESLRQGAFSS-ASDVWMF
 ..   .|    . ...|.. |..|. | | .||||   |.|| .   ||..|||| | |                  ..||| |    ..  ..|.| .
HGLRFPFPE-HARFYMYQICCALEYCHSHGIIHRDLKPENILLDE--HIKICDFGLARQL----------TTFCGTPWYMAPEVL---GYGKCKCDWWSC

GVTLWEMFSGGEEPWAGVPPYLILQRLEKDRARLPKPPLCSRALYSLALRCWAPHPADRPSFSNLEG----LLQEAWL
|..|.||.. |. |.    ........             |. . ..  .|.   |..||.   .        .  |.
GCILYEMLC-GYPPFP--QMQMMFKKIG------------SPEAKDFIRKCLQKDPEKRPTA-EALQDEWDIKCHPWF
Kinase TNK1.AA Pkinase 116-383 22 3.6e-31 111.29 Pfam 1-293 (293) Show / Hide 
Range on Protein: 116-383
Range on HMM: 1-293/293
Sequence Identity: 22% (69 aa)

VRRGELLGSGCFGVVHRGLWTLPSGQSIPVAVKSLRVGPEGPMGTE----LGDFLREVSVMMKLEHPHVLRLHGLVL-GQPLQMVMELAPLG----SLHA
 ..|. .||| ||.| .. .   .|.   |||| ...  | .   .    |    .|...| .| ||...||.. .  .. . ||||... |    .|..
YHIGRKIGSGSFGCVYKCHH-KGTGK--IVAVKIIKKRHEKSWKDQTHRRL----SEIQIMKRLNHPNIVRLYDWFEDKDHIYMVMEYCEGGLYVMDLFD

RLTAPAPTPPL--PVALLCLFLRQLAGAMAYLGSCGLVHRDLATRNLLLASPRMI----KVADFGLVRP--LGGARGRYVMGGPRPIPYAWCAPESLR-Q
....     ..  .   .. ...|.. ...|. |.| .||||   |.|. .   |    |..|||| .   .   .  ..  | ..    ..||| .| .
YIST-WRHGCFYFSEWECKFYMYQILRGLEYCHSMGIIHRDLKPENILIDNNGHIDACVKICDFGLAKQFDY-NNS-MTTFCGTPW----YMAPEVIRGG

GAFSSASDVWMFGVTLWEMFSGGEEPWAGV----PPYLILQRLEKDRA---RLPKPPLCS-------------------RALYSLALRCWAPHPADRPSF
   ....|.| .|..|.||.. |. |. |     . .  .|......    . . | .||                   ... ..  .|... |..||. 
QYYGPKVDMWSCGCILYEMLC-GRPPFPGHCWHDN-HDQMQMICRIMGPPLHFDWPWWCSISYFFFRHWHFHWTFHNWSEECKDFIKWCLCKDPKKRPT-

SNLEGLLQEAWL
   | .||  |.
--AEQILQHPWF
UBA TNK1.AA UBA 603-628 30 0.001666 16.54 Pfam 13-38 (38) Show / Hide 
Range on Protein: 603-628
Range on HMM: 13-38/38
Sequence Identity: 30% (8 aa)

HGVTYQECQVALRTTGGDVASAIRNL
.|.. ..|. ||| ....|. |.  |
TGFSMMQCKKALRACNNNVERAVEWL
UBA TNK1.AA UBA 640-662 17 3.498018 4.7 Pfam 16-38 (38) Show / Hide 
Range on Protein: 640-662
Range on HMM: 16-38/38
Sequence Identity: 17% (4 aa)

SRADCRRILEHHQWDLSAASRYI
|. .|.. |. . ... .|  ..
SMMQCKKALRACNNNVERAVEWL