Gene TSSK2 (Mouse)

TSSK2

Species: Mouse
Alias: Stk22b, TSSK2
External Links: MGI , Entrez Gene , Refseq cDNA , Refseq Protein , Phosphosite , iHOP
Annotation:

Classification

Group: CAMK
Family: TSSK

Sequence

Name Sequence Type Origin Length Description Download
TSSK2.AA Protein Sugen 358 None Fasta, JSON
TSSK2.NA RNA Sugen 1388 None Fasta, JSON
TSSK2.kin_dom Protein Kinase Domain Sugen global kinase HMM prediction 261 Kinase domain by global Sugen HMM Fasta, JSON

Protein domain

Protein domains of TSSK2.AA. The domains are annotated by HMM profiles from Pfam and SMART, as well as in-house data which includes HMMs of each individual kinase group, family and subfamily. Here is domain list in details, including sequence identity, significance and alignment. In particular, you can find can find the best hit kinase group/family/subfamily, which is helpful to understand the relationship between kinases.Kinase domain and best hit kinase group/family/subfamily are highlighted in red and blue. Visualized by pviz.

Usage: Zoom in selected region by dragging mouse and zoom out by double-clicking.

Show/hide domain list
Domain Protein name Domain Name Range Identity (%) Significance Score Profile Source Profile Range (length) Alignment
Kinase TSSK2.AA TSSK 12-272 56 7.4e-196 648.31 In-house 1-289 (289) Show / Hide 
Range on Protein: 12-272
Range on HMM: 1-289/289
Sequence Identity: 56% (164 aa)

YIVGINLGKGSYAKVKSAYSERLKFN----------------VAVKIIDRKKTPTDFVERFLPREMDILAT-VNHRSIIKTYEIFETSDGRIYIVMELGV
|.||...|.||||||..|||.. |..                ||.||||||| |||....|||||..|... ..|..||..||.|||..|.||.|||...
YNVGKKIGHGSYAKVYCAYSKKHKCKHNPRLRDDLRIKRHTHVAIKIIDRKKAPTDYLNKFLPREIQIMRKTLKHPNIIQFYEMFETCQGKIYMVMEYAE

QGDLLEFIKCR------GALHEDVARKMFRQLSSAVKYCHDLDVVHRDLKCENLLLDKDFNIKLSDFGFSKRCLRDGSGRI-VLSKTFCGSAAYAAPEVL
.|||||.|..|      |||||. |||.|||..|||||||...||||||||||.||||..||||.||||.... || .||. .||||||||.||||||.|
HGDLLEYIQRRTQERCCGALHEEQARKWFRQMVSAVKYCHSHNVVHRDLKCENILLDKHWNIKLTDFGFARYWPRDDPGRCCHLSKTFCGSYAYAAPEIL

QGIPYQPKVYDIWSLGVILYIMVCGSMPYDD--SDIKKMLRIQKEHRVDFPR--SKNLTGECKDLIYRILQPDVNRRLHIDEILSHSWL
.||||.||.||.||.||||||||||.||.||  |.|.|||..|.||.| ||.  |.... ||||||...|||....|.||.||..|.|.
RGIPYDPKWYDVWSMGVILYIMVCGCMPFDDDKSNIHKMLWQQQEHKVCFPKPHSCWISQECKDLIRHMLQPHPCNRPHINEICHHCWM
Kinase TSSK2.AA CAMK 17-272 25 1.1e-116 377.66 In-house 1-425 (425) Show / Hide 
Range on Protein: 17-272
Range on HMM: 1-425/425
Sequence Identity: 25% (109 aa)

NLGKGSYAKVKSAYSERLK------------FNVAVKIIDRKKTP-------------------------TDFVERFLPREMDILAT-------VNHRSI
 ||.||..||| ..  . .              ||.||||.|| .                         ... .....||..|. .       ..|. |
TLGRGSFGKVKLCIHKNTTGKERVHHIYTNGQKVAIKIIDKKKLKDKQNQDYSNCYKIDKSKCKHRYCWRRPKDRKNVRREIEIMKKLQGIGNKLDHPNI

IKTYEIFE------------TSDG-------RIYIVM---ELGVQG----DLLEFIKCR---------------GALHEDVARKMFRQLSSAVKYCHDLD
|| ||..|            | .        ..|.||   |.   |    ||...|. .               | ..|. ||..|||. |||.|||...
IKLYEVYEDPHYFKNTNDYET-SKQVFTKDKHMYMVMEIMEYCSGGELFDDLFDYIVEHGCYGEEFDQFDIVERGRFTEREARRYFRQICSAVHYCHSHN

VVHRDLKCENLLLDKD-----------------FNIKLSDFGFSKRCLRDGSGRIV-------------------LSKTFCGSAAYAA-PEVLQG-----
.||||||.||.|||..                 .|||..||||.... .. . .                     . |||||. .|.| ||||.|     
IVHRDLKPENILLDDNNDDSDPVEHDEIFDWNNNNIKIIDFGFANKFDPGENNFMCSDYKGGEMHNQWTTPTEGQKMKTFCGTPEYMAAPEVLNGKGHCN

--------IPYQPKVYDIWSLGVILYIMVCGSMPYDDS-------------DIKKMLRIQKEHRVDFPRSK----------------------NLTGECK
        .|| ..  |.||.|||||||.|| .|....             .......  .. . ||| ..                      ... |||
MQNATDEEKPYYGPKCDMWSCGVILYIMLCGYPPFYGDCDNEICEDEWIGMNDYELFEKIMKGKYDFPPPYFSPISCNYGPEWWDDISDEFHHFVSQECK

DLIYRILQPDVNRRLHIDEILSHSWL
||| ..||.| ..|. |...|.| |.
DLIRKMLQVDPEKRMTIEQCLNHPWM
Kinase TSSK2.AA CAMKL 12-272 38 6.9e-116 371.36 In-house 1-297 (297) Show / Hide 
Range on Protein: 12-272
Range on HMM: 1-297/297
Sequence Identity: 38% (116 aa)

YIVGINLGKGSYAKVKSAYSERL-KFNVAVKIIDRKKTP-TDFVERF-----------LPREMDILATVN---HRSIIKTYEIFETSD-----GRIYIVM
|..|  |||||..||| |  .|. .  ||.||||.||.   .....            . ||. |.  .|   |  ||| ||..||..     . ||.||
YRIGKTLGKGSFGKVKLATHIRTTGEKVAIKIIDKKKIWNDPWMKKNKCGQKHESDMRIRREIQIMKMLNIGKHPNIIKLYEVIETPEHDIETKKIYLVM

ELGVQGD--LLEFIKCRGA----LHEDVARKMFRQLSSAVKYCHDLDVVHRDLKCENLLLDKDF--NIKLSDFGFSKRCLR--DGSGRIVLSKTFCGSAA
|.   |.  |...|. .|     ..|. ||..|||. |||.|||....||||.| ||.|||..   |||..|||||  . .  .|.|.  . |||||| .
EYCSGGEMDLFDYIVKHGHRRGRMPEHEARRYFRQIVSAVNYCHSHGIVHRDIKPENILLDENGNNNIKIIDFGFSNMYRPCIFGPGQ--KLKTFCGSPP

YAAPEVLQG--IPYQPKVYDIWSLGVILYIMVCGSMPYDDS--------DIKKMLRIQKEHRVDFPRSKNLTGECKDLIYRILQPDVNRRLHIDEILSHS
|.|||..||   ||  .  ||||.||||| |||| .| ||         .| .........   .|  . .  .|.||| ..||.. ..|  |..|..| 
YMAPEIFQGNNKPYDGPKVDIWSCGVILYAMVCGYLPFDDDTYNKQGKDNI-YLYWKIMCG-YYPPIWYHVS-DCRDLIRKMLQVNPEKRPTIHQIMNHP

WL
|.
WM
Kinase TSSK2.AA MARK 12-272 38 6.1e-97 317.39 In-house 1-262 (262) Show / Hide 
Range on Protein: 12-272
Range on HMM: 1-262/262
Sequence Identity: 38% (104 aa)

YIVGINLGKGSYAKVKSAYSERLKFNVAVKIIDRKKTPTDFVE-RFLPREMDILATVNHRSIIKTYEIFE--TSDGRIYIVMELGVQGDLLEFIKCR--G
| ..  .|.||||||| | . . . .||.||....|  .|. . . . ||..|.  ..|  ||| ....|  |.   ||..||.   |.|...|| .  |
YKMLKTIGHGSYAKVKLACHKHTGRKVAIKIYEKFK-LNDPQWMKNVMREIEIMKKLDHPNIIKLFHVIEQDTEQHQIYLIMEYASGGELYDYIKAHPNG

ALHEDVARKMFRQLSSAVKYCHDLDVVHRDLKCENLLLDKDF--NIKLSDFGFSKRCLRDGSGRIVLSKTFCGSAAYAAPEVLQGIPYQPKVYDIWSLGV
 |||. ||..|||. |||.|||. ..||||.|.||.|.|..   |||..||||| ..  .      . .||||. .|.|||.... ||  .  |||||||
RLHEEEARRIFRQIVSAVNYCHSKNIVHRDIKPENILIDENGNHNIKIIDFGFSICIPPG-----QKLNTFCGTPPYMAPEIFLKKPYDGPKVDIWSLGV

ILYIMVCGSMPYDDSD--IKKM-LRIQKEHRVDFPRSKNLTGECKDLIYRILQPDVNRRLHIDEILSHSWL
.||.||||. |.|...  .|..  .|....   ...   .  ||..|| |.|... ..|  |.||..|.|.
VLYFMVCGYFPFDGDTQDYKELYKKILRGKYDIPCH---VSKECRNLIQRLLTVNPEERPTIEEIMKHPWM
Kinase TSSK2.AA S_TKc 12-272 32 8.2e-93 315.57 SMART 1-231 (231) Show / Hide 
Range on Protein: 12-272
Range on HMM: 1-231/231
Sequence Identity: 32% (89 aa)

YIVGINLGKGSYAKVKSAYSERLKFNVAVKIIDRKKTPTDFVERFLPREMDILATVNHRSIIKTYEIFETSDGRIYIVMELGVQ--GDLLEFIKCRGA--
| ..  .|||...||. ..  . .  ||.|||.          . . ||..||   .|  |.| |..|..  ...|.|||.  .  |||...|| ||   
YEILRKIGKGAFGKVYKCRHKKTGRIVAIKIIK----------EHIRREIQILKK-HHPNIVKLYDVFQD--DHLYMVMEYCDGDLGDLFDYIKKRGRHG

----LHEDVARKMFRQLSSAVKYCHDLDVVHRDLKCENLLLDKDFNIKLSDFGFSKRCLRDGSGRIVLSKTFCGSAAYAAPEVLQGIPYQPKVYDIWSLG
    ..| .||....|. .|..|||.. ..||||| ||.|||.  .||..|||....            .||||.  | |||||   .| ..  |.||.|
LRFPFPE-HARFYMYQICCALEYCHSHGIIHRDLKPENILLDE--HIKICDFGLARQL-----------TTFCGTPWYMAPEVL---GYGKCKCDWWSCG

VILYIMVCGSMPYDDSDIKKMLRIQKEHRVDFPRSKNLTGECKDLIYRILQPDVNRRLHIDEILS-------HSWL
.|||.|.||  |..  ....|... .            . |.||.| ..|| | ..|. . |.|        | |.
CILYEMLCGYPPFP--QMQMMFKKIG------------SPEAKDFIRKCLQKDPEKRPTA-EALQDEWDIKCHPWF
Kinase TSSK2.AA AMPK 12-272 41 1.6e-88 262.93 In-house 1-254 (254) Show / Hide 
Range on Protein: 12-272
Range on HMM: 1-254/254
Sequence Identity: 41% (108 aa)

YIVGINLGKGSYAKVKSAYSERLKFNVAVKIIDRKKTPTDFVERFLPREMDILATVNHRSIIKTYEIF-ETSDGRIYIVMELGVQGDLLEFIKCRGALHE
||.| ..|.|.. ||| .. .. .  ||.||....|   . .   . || .||  ..| .||. ||.  || .  |..|||    |.| ..|  .| | |
YIIGKTIGEGTFGKVKMGTHILTGEKVAIKILNKQKIKDQDMVERIQREIHILKLFRHPHIIQLYEVIIETPT-DIFMVMEYVSGGELFDYIVKHGRLQE

DVARKMFRQLSSAVKYCHDLDVVHRDLKCENLLLDKDFNIKLSDFGFSKRCLRDGSGRIVLSKTFCGSAAYAAPEVLQGIPYQPKVYDIWSLGVILYIMV
. |.. | |  |.| |||.. .|||||| ||||||.. |||. ||| |. .  ||     | || |||  |||||. .| .|     |||| ||||| |.
REACRFFQQIISGVEYCHRHMIVHRDLKPENLLLDHNKNIKIVDFGLSNMM-KDG---EFL-KTACGSPCYAAPEMISGKLYCGPEVDIWSCGVILYAML

CGSMPYDDSDIKKMLRIQKEHRVDFPRSKNLTGECKDLIYRILQPDVNRRLHIDEILSHSWL
||  | ||... .  .  |. ..  |  |.|. |.|||| ..||.| . |. |..|  |.|.
CGYLPFDDENTPTLYKKIKNGEYYIP--KFLSPEAKDLIKHMLQVDPMKRITIHDIRNHPWF
Kinase TSSK2.AA NuaK 12-272 39 2.4e-88 232.31 In-house 1-252 (252) Show / Hide 
Range on Protein: 12-272
Range on HMM: 1-252/252
Sequence Identity: 39% (104 aa)

YIVGINLGKGSYAKVKSAYSERLKFNVAVKIIDRKKTPTDFVERFLPREMDILATVNHRSIIKTYEIFETSDGRIYIVMELGVQGDLLEFIKCRGALHED
| .   |||| | ||| |. .     ||.| | ..|   .   .   ||  |. ..||  ||. ||.|| .| .| ||||   .|.| ..|  .. | | 
YEFQKTLGKGTYGKVKLATEHSTGREVAIKSIKKCKIEDEQDMVHIRREIEIMSSLNHPHIIHIYEVFENKD-KIVIVMEYASGGELYDYISECKSLPER

VARKMFRQLSSAVKYCHDLDVVHRDLKCENLLLDKDFNIKLSDFGFSKRCLRDGSGRIVLSKTFCGSAAYAAPEVLQGIPYQ-PKVYDIWSLGVILYIMV
 ||..|||  ||| |||   ..||||| || |||.. |.|  ||| |     .      . .|||||  || ||.  | ||. | | | |||||.||.||
EARHFFRQIVSAVHYCHKHRICHRDLKLENILLDQNCNAKIADFGLSNYYHDQ-----KFLHTFCGSPLYASPEIVNGQPYHGPEV-DCWSLGVLLYTMV

CGSMPYDDSDIKKMLRIQKEHRVDFPRSKNLTGECKDLIYRILQPDVNRRLHIDEILSHSWL
 |.||.| .| |.. .  .. .   |.      .   ||  .|. . .||  | .| .| |.
YGTMPFDGHDFKHLVKQISQGAYYEPCK---PSDACMLIRWMLMVNPRRRATIYDICHHWWV
Kinase TSSK2.AA QIK 12-272 34 7.6e-77 261.6 In-house 1-272 (272) Show / Hide 
Range on Protein: 12-272
Range on HMM: 1-272/272
Sequence Identity: 34% (98 aa)

YIVGINLGKGSYAKVKSAYSERLKFNVAVKIIDRKKTPTDFVERFLPREMDILATVNHRSIIKTYEIFETSDGRIYIVMELGVQGDLLEFIKCRGA----
| ..  .||| .| || |     |  ||.||||. .   .  ..   ||  |.   .|  ||| |.. || |  .|||.|   .|.. . .   |     
YDIERTIGKGNFAVVKLARHRITKTKVAIKIIDKSQLDEENLQKCY-REVQIMKMLYHPHIIKLYQVMETDD-MMYIVTEYCSNGEMFDYLCKHGRKGVK

----------------LHEDVARKMFRQLSSAVKYCHDLDVVHRDLKCENLLLDKDFNIKLSDFGFSKRCLRDGSGRIVLSKTFCGSAAYAAPEVLQGIP
                . |..||..| |. |||.|||.. .|||||| ||.|||.. |||. |||||     .      | .|.||| .|||||...|. 
MVNSPDIGDQVLMGVPMAENEARRWFWQICSAVHYCHKRNIVHRDLKAENILLDNNMNIKIADFGFSNWFKQG-----QLLMTWCGSPPYAAPEMFEGKE

YQPKVYDIWSLGVILYIMVCGSMPYDDSDIKKMLRIQKEHRVDFPRSKNLTGECKDLIYRILQPDVNRRLHIDEILSHSWL
|     ||||.||.||..|||..|.| . .... .   . ..  | .  .  .| .|| . |  | ..|. |. |. | |.
YDGPKVDIWSMGVVLYVLVCGALPFDGKTLQNLRQRVLSGKFRIPFF--MSQDCEHLIRHMLVVDPEHRYTIMQICQHRWM
Kinase TSSK2.AA Pkinase 12-272 30 1.8e-74 258.48 Pfam 1-293 (293) Show / Hide 
Range on Protein: 12-272
Range on HMM: 1-293/293
Sequence Identity: 30% (90 aa)

YIVGINLGKGSYAKVKSAYSERLKFNVAVKIIDRKKTPTDFVERFLP-REMDILATVNHRSIIKTYEIFETSDGRIYIVMELGVQG----DLLEFIK--C
| .|  .|.||...|. ..       ||||||.....  .. .. .  .|  |.. .||  |...|..||. ...||.|||.   |    || ..|.   
YHIGRKIGSGSFGCVYKCHHKGTGKIVAVKIIKKRHEKSWKDQTHRRLSEIQIMKRLNHPNIVRLYDWFED-KDHIYMVMEYCEGGLYVMDLFDYISTWR

RGAL--HEDVARKMFRQLSSAVKYCHDLDVVHRDLKCENLLLDKDFNI----KLSDFGFSKRCLRDGSGRIVLSKTFCGSAAYAAPEVLQ-GIPYQPKVY
.|..   |........|. ....|||.  ..||||| ||.|.|.. .|    |..|||..|        . .  .||||.  |.||||.. | .| ||| 
HGCFYFSEWECKFYMYQILRGLEYCHSMGIIHRDLKPENILIDNNGHIDACVKICDFGLAKQFD---Y-NNS-MTTFCGTPWYMAPEVIRGGQYYGPKV-

DIWSLGVILYIMVCGSMPYDDS------DIKKMLRIQKEHRVDFPRSKNLT-------------------GECKDLIYRILQPDVNRRLHIDEILSHSWL
|.||.|.|||.|.||  |....      | ..|..  .. ...|....  .                    ||||.|...|..| ..|. ...|| | |.
DMWSCGCILYEMLCGRPPFPGHCWHDNHDQMQMICRIMGPPLHFDWPWWCSISYFFFRHWHFHWTFHNWSEECKDFIKWCLCKDPKKRPTAEQILQHPWF
Kinase TSSK2.AA Ciliate-E2 12-272 24 4.4e-70 239.14 In-house 1-365 (365) Show / Hide 
Range on Protein: 12-272
Range on HMM: 1-365/365
Sequence Identity: 24% (94 aa)

YIVGINLGKGSYAKVKSA--YSERLKFN---------------------VAVKIIDRKKTPTDFVERFLPREMD----------ILATVNHRSIIKTYEI
|..   .|.|....|. .  .... .|.                     .|.||.  ..    . |  . ||..          || ..||  ||| || 
YKFIKKIGQGNFGSVYKCKVWKVQKQFAIKIIDQKQQRQQMQEKVKIKIYAMKIMKKNQIEQIKQEIHIMREINCFYKKINEKNILEQLNHPNIIKMYEC

FET-SDGRIYIVMELGVQGDLLEFIKCR-----------GALHEDVARKMFRQLSS---------------AVKYCHDLD-VVHRDLKCENLLLDKDFNI
|.. .|  ||.|||.  .|||...|| .           . . |  ......|. .               |..|.|    ..|||.| ||.|.     |
FQEKDDNNIYLVMEYCQGGDLFDYIKNNKKKRNHEIEKDKYFTEKEIKYIMKQILQGFKTKAEFYIACIILALEYLHSKNNIIHRDIKPENILF-----I

KLSDFGFSKRCLRD------GSGRI---------------------VLSKTFCGSAAYAAPEVLQGIPY--------QPKVYDIWSLGVILYIMVCGSMP
|..|||.||..  |      ....                       . .|.||.. | |||.|.| .|          .  ||||||||||.|..|  |
KIIDFGLSKKYDDDNQNRTHKQQCKWYMFKNDTSRTPGYMDQIIQQNMFNTICGTPGYMAPEILNGKKYDNQQKQKGYDYKCDIWSLGVILYEMLFGKPP

YDDSDIKKMLRIQKEHRVDFP----------------RSKNLTGECKDLIYR----ILQPDVNRRLH-IDEILSHSWL
.        ....|.  .|||                  |... |||||| .    .|| | . |.  ...|| | |.
F--------QQQIKQCKIDFPCPEWQKDTQCIQCKWKSWKKWSQECKDLIKKFGKRMLQKDPEKRITGWEQILNHPWF
Kinase TSSK2.AA Ciliate-E2-Unclassified 12-272 24 1.3e-63 217.67 In-house 1-352 (352) Show / Hide 
Range on Protein: 12-272
Range on HMM: 1-352/352
Sequence Identity: 24% (86 aa)

YIVGINLGKGSYAKVKSAYSERLKFNV-----AVKIIDRKKTPTDFVERFLPREMDILAT-----------------VNHRSIIKTYEIFE-TSDGRIYI
|...  .|.|...||. .. .  |  .     . ||...|.    ...  . .||...                   .|| .... ..... ...  |||
YKIIKQIGQGGFGKVYKCQHKKQK-QYYAMKYMKKIQIYKQKQIMNKD-EIMNEMKEMNNKKKYHQRKYNKIMQQILLNHPHPFIVKMFYCFQDKQNIYI

VMELGVQGDLLEFIK-----------------CRGALHEDVAR-----KMFRQLSSAVKYCHDLD-VVHRDLKCENLLLDKD---FNIKLSDFGFSKRCL
|||.  .|||...||                 .|  . |  |.     ..|.|. .. .|.|    ..|||.|.||.|.|..   ..||..|||.||.  
VMEYCEGGDLWQYIKKRKKQKQKGNDLFHNMKQRKIFTEQQAKYKKAKFYFAQILQGLEYLHHKNNIIHRDIKPENILFDNNGKNYYIKIIDFGISKKYQ

RD---GSGR---------IVLSKTFCGSAAYA----APEVLQG-IPYQP--KVYDIWSLGVILYIMVCGSMPYDDSDIKK----------------MLRI
 .     ..           ...||||.  |     |||||||  ....  .  |||||||||| |. |  |..| . ..                ....
QNNNCD-TNQQQKMQIWKQQMMWTFCGTPNYMPQYTAPEVLQGQNYDHSKAYKCDIWSLGVILYEMLFGYYPFYDNNCEQHQQLITQWINNAYRKQLYQN

QKEHRVDFPRSKN------LTGECKDLIY----RILQPDVNRRLHIDEILSHSWL
.|.  ..|| ...      .  |.||.|     ..|. . | |. ...|| | |.
IKQKNIQFPKFPWQQIPKHWSPEAKDFINDLLQKMLKKNPNKRITFEQILNHPWF
Kinase TSSK2.AA ULK 12-272 29 3.7e-61 209.51 In-house 1-329 (329) Show / Hide 
Range on Protein: 12-272
Range on HMM: 1-329/329
Sequence Identity: 29% (96 aa)

YIVGINLGKGSYAKVKSAYSERLK----FNVAVKIIDRKKTPTDFVER-------FLPREMDILATVN--------HRSIIKTYEIFETSDG-RIYIVME
|..   |||||..||  .. .. |      ||.|.||..|   .  |.       .| .| .|. . .        |  |.| |..||||.   |||.||
YCLNHCLGKGSFGKVYKGRNKKTKDYVNEKVACKMIDKQKMNQKNNEQEGQYMWQLLKNEIKIMKKLKSPNRHKNHHPNIVKLYDWFETSNHNNIYIIME

LGVQGDLLEFIKCRGALHEDV----------ARKMFRQLSSAVKYCHDLDVVHRDLKCENLLLDKDFN------------IKLSDFGFSKRCLRDG-SGR
.  .||| ..|| .. | ||.          |.. |.|. .. |. |.  ..|||.| .| |.....             .|..||||.| .  |. . .
YCNGGDLEQYIKKNKKLPEDTEEKKRLSEQEAIQFFKQILNGFKELHKHNIIHRDIKPQNILIHNGQPKTDSKKVHPNGVLKIADFGFAKHVDNDNMEQQ

IVLSKT----FCGSAAYAAPEVLQ----GIPYQPKVYDIWSLGVILYIMVCGSMP---YDDSDIK-----KMLRIQKEHR-------VDFP---RSKNLT
. .. .    .||.  | ||..||    ..||  .  ||||||.|.| |. |  |   .  .| .     | ........        .||    .... 
MMMTCVNEKRLCGTPLYMAPQILQGQGEQKPYYDYKCDIWSLGCIFYEMLYGKPPFYAW-FNDQYLQIIQKLINNPPPWPQQIKKQPLQFPKDGNDPQIS

GECKDLIYRILQPDVNRRLHIDEILSHSWL
 ||||||.| || | . |  ..|...| |.
PECKDLIRRMLQYDEKDRISWEELFNHPWF
Kinase TSSK2.AA TyrKc 12-272 22 1.9e-15 26.98 SMART 1-280 (280) Show / Hide 
Range on Protein: 12-272
Range on HMM: 1-280/280
Sequence Identity: 22% (65 aa)

YIVGINLGKGSYAKVKSAYSERLKFNVAVKIIDRKKTPTDFVERFLPREMDILATV--NHRSIIKTYEIFETS------DGRIYIVMELGVQGDLLEFI-
   |  || | . .|  .       .|||| .   .     .| |. ||. |.  .  .|  |.. | .  ..      .. ..||||.   |||.... 
ITLGKKLGEGAFGEVYKGTWK---IQVAVKMLKEDA-----REDFM-REARIMCKLGGHHPNIVRLYGVCTQQGRNFMYIEPLMIVMEYMPHGDLKDYLR

KCRGALHEDVARKMFRQLSSAVKYCHDLDVVHRDLKCENLLLDKDFNIKLSDFGFSKRCLRD-----GSGRIVL----SKTFCGSAAYAAPEVLQGIPYQ
|.|. |  .   ..  | ..   | |.  ..|||| . | |..... .| |||| |.    |      .  ..     .. .       |||...   . 
KHRPKLCMKDLLSFCWQIACGMEYLHSKNCIHRDLAARNCLVGENHTVKISDFGLSRDIYDDDQQGESKDYYRKKEHKGGKTMLPIRWMAPECINYGKFT

PKVYDIWSLGVILY-IMVCGSMPYDD------SDIKKMLRIQKEHRVDFPRSKN------LTGECKDLIYRILQPDVNRRLHIDEILSHSWL
.|  |.|| || .. |.  | .|| .      |..  . .... .| . | .         . |  ... .  . | . |    ||  |. .
TKS-DVWSFGVCMWEIFTYGQQPYPGMIQQMMSNQEVIEYVKQGYRMPQPPNDYPMSFVCCPDEMYQIMKQCWHEDPEDRPTFSEI--HECF
Kinase TSSK2.AA Pkinase_Tyr 12-156 26 3.1e-12 42.06 Pfam 1-156 (270) Show / Hide 
Range on Protein: 12-156
Range on HMM: 1-156/270
Sequence Identity: 26% (41 aa)

YIVGINLGKGSYAKVKSAYSE----RLKFNVAVKIIDRKKTPTD-FVERFLPREMDILATV-NHRSIIKTYEIFETSDGR--IYIVMELGVQGDLLEFIK
 . |  ||.|.. .|. ..        |  ||||..  . .. . . | |.  |. |. .  .|  |.. | .    ..   ||||||.   ||||.. .
ITFGKKLGEGAFGEVYKGTWKGDPDNTKIPVAVKMLKEGAMHEQNCREDFMR-EAKIMKQLGHHPNIVRLYGVCTDQGEPNQIYIVMEYMPHGDLLDYLR

C----RGALHEDVARKMFRQLSSAVKYCHDLDVVHRDLKCENLLLDKDFNIKLSDFG
     ...|      .| .| ...  | ..   .|||| . | |..... .| .|||
KHREDKQPLTMKDLLQMCWQIAKGMEYLESKNCIHRDLAARNCLVTENNVVKICDFG