Gene TTBK2 (Mouse)

TTBK2

Species: Mouse
Alias: TTBK2, B930008N24Rik
External Links: MGI , Entrez Gene , Refseq cDNA , Refseq Protein , Phosphosite , iHOP
Annotation:

Classification

Group: CK1
Family: TTBK

Sequence

Name Sequence Type Origin Length Description Download
TTBK2.kin_dom Protein Kinase Domain Sugen global kinase HMM prediction 256 Kinase domain by global Sugen HMM Fasta, JSON
TTBK2.AA Protein Sugen 1312 None Fasta, JSON
TTBK2.NA RNA Sugen 10906 None Fasta, JSON

Protein domain

Protein domains of TTBK2.AA. The domains are annotated by HMM profiles from Pfam and SMART, as well as in-house data which includes HMMs of each individual kinase group, family and subfamily. Here is domain list in details, including sequence identity, significance and alignment. In particular, you can find can find the best hit kinase group/family/subfamily, which is helpful to understand the relationship between kinases.Kinase domain and best hit kinase group/family/subfamily are highlighted in red and blue. Visualized by pviz.

Usage: Zoom in selected region by dragging mouse and zoom out by double-clicking.

Show/hide domain list
Domain Protein name Domain Name Range Identity (%) Significance Score Profile Source Profile Range (length) Alignment
Kinase TTBK2.AA TTBK 90-345 82 2.4e-219 735.0 In-house 1-257 (257) Show / Hide 
Range on Protein: 90-345
Range on HMM: 1-257/257
Sequence Identity: 82% (212 aa)

WKVLRKIGGGGFGEIYDALDMLTR-ENVALKVESAQQPKQVLKMEVAVLKKLQGKDHVCRFIGCGRNDRFNYVVMQLQGRNLADLRRSQSRGTFTISTTL
|||..|||||||||||.|.||... |.||.||||||||||||||||||||||||.|||||||||||||.|||.||||||.|||||||.|.||.|..||||
WKVVKKIGGGGFGEIYEAKDMINHHEQVAIKVESAQQPKQVLKMEVAVLKKLQGCDHVCRFIGCGRNDKFNYMVMQLQGKNLADLRRKQPRGCFSLSTTL

RLGKQILESIESIHSVGFLHRDIKPSNFAMGRFPSTCRKCFMLDFGLARQFTNSCGDVRPPRAVAGFRGTVRYASINAHRNREMGRHDDLWSLFYMLVEF
|||.|||.||||||||||||||||||||||||.|||||||.|||||||||.||.||.|||||.|||||||||||||||||||||||||||||||||||||
RLGVQILQSIESIHSVGFLHRDIKPSNFAMGRNPSTCRKCYMLDFGLARQYTNACGEVRPPREVAGFRGTVRYASINAHRNREMGRHDDLWSLFYMLVEF

VVGQLPWRKIKDKEQVGSIKERYDHRLMLKHLPPEFSTFLDHISSLDYFTKPDYQLL
|.|||||||||||.|||..||.||||..|||.|.||..|.|||.||.|...|||||.
VQGQLPWRKIKDKDQVGEMKEKYDHRMLLKHCPHEFHQFMDHIKSLNYEDRPDYQLI
Kinase TTBK2.AA CK1 90-345 33 5.6e-122 411.53 In-house 1-339 (339) Show / Hide 
Range on Protein: 90-345
Range on HMM: 1-339/339
Sequence Identity: 33% (115 aa)

WKVLRKIGGGGFG-EIYDA-----LDMLTR-----ENVALKVESAQQPKQ-VLKMEVAVLKKL---------------------QGKDHVCRFIGCGRND
||| .|||.|||| .|| .      || .      | .|.|||.... .|  ..||.....|.                     .|. |.|... .|..|
WKVVKKIGEGGFGYQIYKVQKEDHKDMKNNKPYKGEEYAMKVEPKKSMGQHPQLMEEYQMYKKLQGGKKWKASILKHKHFCKKHCGCPHPCMYWYHGEED

R-FNYVVMQLQGRNLADLRR-SQS-RGTFTISTTLRLGKQILESIESIHSVGFLHRDIKPSNFAMGRFPS------------TCRKCFMLDFGLAR-QFT
. .||.||.| |.|| |||. ..  .. |. .|.|... |.||..| .|. ||.||||||.||.||| .|            ..|. .|.|||.|| ...
DYYNYMVMTLLGPNLEDLRKQNRMCNRKFSMKTWLMIAIQMLEALEYMHDCGFIHRDIKPDNFCMGRNESFKYGKHHHEWNNEHRQVYMIDFGMARRKYR

NSCGDV------------RPPRA---VAGFRG-TVRYASINAHRNREMGRHDDLWSLFYMLVEFVVGQ--LPWRKIKDKEQ-----VGSIKERYDHRLML
.. |..            ||||     .|||| |.||.|||.|...|.||.|||||.||||.|...|.  |||...||...     |.  |. . ..  .
DKDGHNRWNGPRDKTWQHRPPREHKKKKGFRGCTARYCSINCHLGKEQGRRDDLWSWFYMLIEWLKGTPGLPWQNMKDEMKPKDHQVEKMKYEFIDEKKM

------------KHLPPEFSTFLDHISSLDYFTKPDYQLL
            ...|.|| .....|.||.|...|||. .
STPFFLCCPKKDHDCPQEF-KIMKYIRSLKYYDRPDYEMI
Kinase TTBK2.AA TTBKL 90-349 36 1.4e-110 373.7 In-house 1-288 (288) Show / Hide 
Range on Protein: 90-349
Range on HMM: 1-288/288
Sequence Identity: 36% (105 aa)

WKVLRKIGGGGFGEIYDALDMLT-RENVALKVESAQQPK--QVLKMEVAVLKKLQ--GKDHVCRFIGCGRNDRFNYVVMQLQGRNLADLRRSQSRGT-FT
|.. ..||.||||..| . || .  .  |.|.|. .. .  ...|||| ||.|||  |. |.......|.....|..||.| |.|| |||.   ..  |.
WMIVKMIGEGGFGQVYHVWDMKDKKDCAAMKEEKNRLEGGDSRMKMEVHVLMKLQPNGSPHFPKCHCSGKRKDYNFMVMTLCGPNLQDLRKMMPNKKRFS

ISTTLRLGKQILESIESIHSVGFLHRDIKPSNFAMGRFPST---CRKCFMLDFGLARQFTNSCGDV-----------RPPRA---VAGFRGTVRYASINA
 .|..|.| |.|...  .|..||.|||.||.|...|   ..   ||  . .|||.|||. ...|.            |.||     |.||||.||.|.|.
DGTWSRIGIQCLYALKQMHDCGFIHRDVKPCNCCWGYHDHSCERCRHVYLIDFGMARQYAWKDGEWNGPIHENKWMMRRPRNFRHKAPFRGTTRYCSPNM

HRNREMGRHDDLWSLFYMLVEFVVGQLPWRKIKDKEQVGSIKERYDHRLMLKH------LPPEFSTFLDHISSLDYFTKPDYQLLTSVF
|. .| ||||||||..||..|...| |||. ..||..... |.   . .. |       .|.||  |  |..||.|   |||. .  .|
HDRKEQGRHDDLWSWMYMIIELHCG-LPWTNMEDKMEIEHMKKNMKDEDLFKDMPRDHDCPSEFCKFMKHLRSLRYYDRPDYEMIYECF
Kinase TTBK2.AA Worm6 90-345 39 4.7e-110 371.92 In-house 1-279 (279) Show / Hide 
Range on Protein: 90-345
Range on HMM: 1-279/279
Sequence Identity: 39% (109 aa)

WKVLRKIGGGGFGEIYDALDMLTREN--VALKVES--AQQPKQVLKMEVAVLKKLQGKD--HVCRFIGCGRNDR--FNYVVMQLQGRNLADLRRSQSRGT
|||..||| |||| .| ..|  . ..  .|.|.|.  .. ..|.||||..|||..  .   |.|... .|. |.  |||.||.| |.||.|||. .  . 
WKVTKKIGEGGFGAVYKVEDKSDKKKKQFAMKCEKQMENMKRQMLKMECMVLKAVKHHKCRHFCKIEDRGKVDNRGFNYIVMTLVGKNLWDLRKNRPDRK

FTISTTLRLGKQILESIESIHSVGFLHRDIKPSNFAMGRF----PSTCRKCFMLDFGLAR--QFTNSCGDVRPPR-AVAGFRGTVRYASINAHRNREMGR
|. .|.|... | ||.||  |..||.|||.||.||. ||         .. .|||||..|  .. |  ...|.|| ...|||||||||....|...|..|
FSMGTGLKIAIQCLEAIEDLHNCGFIHRDVKPGNFCIGRYQMKEDNEHHTIYMLDFGMCRRKKYCNKGNELRTPRWTACGFRGTVRYAPLACHKGQEQCR

HDDLWSLFYMLVEFVVGQLPWRKIKDKEQVGSIKER--YDH-----RLMLKHLPP-EFSTFLDHISSLDYFTKPDYQLL
 ||. | |||.||..||.||||..||. .|. .|..  ..      |....  |. ||.  .| | ...|...|||. .
KDDCESWFYMMVEMIVGCLPWRHMKDHDHVEKHKKWCRRRTRAPMMRMFFGPCPKEEFNDIMDYIDQYSYWDRPDYKFI
Kinase TTBK2.AA CK1 90-343 34 1.1e-61 211.04 In-house 1-271 (271) Show / Hide 
Range on Protein: 90-343
Range on HMM: 1-271/271
Sequence Identity: 34% (96 aa)

WKVLRKIGGGGFGEIYDALDMLTREN---VALKVESAQQPKQVLKMEVAVLKKLQG------KDHVCRFIGCGRN--DRFNYVVMQLQGRNLADLRRSQS
 .| |||| | ||.|| . .| | ..   || |.|.. .  . |. |. ..| |||        .. . . ||..    .|..|| | |..| ||    .
YRVGRKIGQGSFGDIYLGINM-TNGEENHVAIKLEKNKSKHPQLHYEAKIYKILQGHNCDNQCHGIPHMYWCGQEEQGDYNIMVMDLLGPSLEDLFNFCN

RGTFTISTTLRLGKQILESIESIHSVGFLHRDIKPSNFAMGRFPSTCRKCFMLDFGLARQFTNSCGDVR-----PPRAVAGFRGTVRYASINAHRNREMG
|  |.. |.| .. |... || .|. .|.|||||| || |||    | .... ||||| ..     | .     | |   .. ||.||||||.|  .| .
R-KFSLKTVLMIADQMIQRIEYVHNKNFIHRDIKPDNFLMGRYGKHCHQVYIIDFGLAKRYR----DDKTHQHIPYRENKNLTGTARYASINTHLGIEQS

RHDDLWSLFYMLVEFVVGQLPWRKIKDK------EQVGSIKERYDHRLMLKH-LPPEFSTFLDHISSLDYFTKPDYQ
| ||. || |.|. |  |.|||  .| .      |. . .|  . .  . |  .| || ..| .. .|... ||||.
RRDDMESLGYVLMYFLRGSLPWQGLKANTKKQKYEKIMEKKMSTPVEQLCKGNFPNEFAMYLNYCRQLHFEEKPDYM
Kinase TTBK2.AA CK1-A 90-345 36 6.9e-52 178.7 In-house 1-261 (261) Show / Hide 
Range on Protein: 90-345
Range on HMM: 1-261/261
Sequence Identity: 36% (95 aa)

WKVLRKIGGGGFGEIYDALDMLTRENVALKVESAQQPKQVLKMEVAVLKKLQGKDHVCRFIGCGRNDRFNYVVMQLQGRNLADLRRSQSRGTFTISTTLR
....|||| | ||.|| .. .   |.||.|.||..     |  |  | . |||   . .    |..  .| .||.| |  | ||    .|  ||. | | 
YRLVRKIGSGSFGDIYLGINITNGEEVAIKMESNKARHPQLIYEAKVYRILQGCVGIPHMRWYGCEKDYNVMVMDLLGPSLEDLFNFCKR-RFTMKTVLM

LGKQILESIESIHSVGFLHRDIKPSNFAMGRFPSTCRKCFMLDFGLARQFTNSCGDVR-PPRAVAGFRGTVRYASINAHRNREMGRHDDLWSLFYMLVEF
|  |..  || .|  .|.|||||| || ||     | | |..|||||...  |      | |      ||.||||||||   |  | ||. |. |... |
LADQMIMRIEYVHEKNFIHRDIKPDNFLMG-IGRHCNKLFLIDFGLAKKYRDSRTRQHIPYREDKNLTGTARYASINAHLGIEQSRRDDMESMGYVMMYF

VVGQLPWRKIKDK------EQVGSIKERYDHRLMLKHLPPEFSTFLDHISSLDYFTKPDYQLL
  |.|||  .| .      |..   |       . |  | ||. .. .. .| .  .|||  |
NRGKLPWQGMKAMTKKQKYEKISEKKMSTPIEQLCKGFPAEFCMYMNYCRNLRFEEQPDYMYL
Kinase TTBK2.AA CK1-D 90-345 35 4.9e-51 175.86 In-house 1-261 (261) Show / Hide 
Range on Protein: 90-345
Range on HMM: 1-261/261
Sequence Identity: 35% (94 aa)

WKVLRKIGGGGFGEIYDALDMLTRENVALKVESAQQPKQVLKMEVAVLKKLQGKDHVCRFIGCGRNDRFNYVVMQLQGRNLADLRRSQSRGTFTISTTLR
... ||||.| ||.||   .. | | ||.|.|...     |..|  . | .||   . .   ||..  .| .||.| |  | ||    .|  | . | | 
YRIGRKIGSGSFGDIYHGTNIQTNEEVAIKLECIKTKHPQLHIESKFYKMMQGGIGIPEIRWCGQEGDYNVMVMDLLGPSLEDLFNYCHR-KFSLKTVLM

LGKQILESIESIHSVGFLHRDIKPSNFAMGRFPSTCRKCFMLDFGLARQFTNSC-GDVRPPRAVAGFRGTVRYASINAHRNREMGRHDDLWSLFYMLVEF
|. |..  || ||.  |.|||||| || ||         ...|||||...  .      | |      || |||||| |.  |  | ||| || |.|. |
LADQMICRIEYIHCRNFIHRDIKPDNFLMG-LGKRGNMVYIIDFGLAKRYRDARTHQHIPYRENKNLTGTARYASINTHQGIEQSRRDDLESLGYVLMYF

VVGQLPWRKIKDK------EQVGSIKERYDHRLMLKHLPPEFSTFLDHISSLDYFTKPDYQLL
  | |||  .|        |..   |       . | .| ||......  .| .  ||||  |
NRGSLPWQGLKAATKRQKYERICEKKMSTKIDTLCKGYPSEFQQYMNYCRNLKFDDKPDYCYL
Kinase TTBK2.AA CK1-Unclassified 90-236 34 4.9e-46 133.87 In-house 1-155 (244) Show / Hide 
Range on Protein: 90-236
Range on HMM: 1-155/244
Sequence Identity: 34% (54 aa)

WKVLRKIGGGGFGEIYDALDMLTRENVALKVESAQQPKQVLKMEVAVLKKLQGKD-------HVCRFIGCGRNDR--FNYVVMQLQGRNLADLRRSQSRG
 .|..||| | ||||| . .| | |.||.|.|.. .    |. |. ... ||.         .. . . ||...   .|..|| | |..| ||     | 
YRVIEKIGQGSFGEIYKCINMQTNEEVAIKLEKKNSKHPQLCYEAKIMQYLQNGHNCDNFIKGIPKMYWCGQEEQGDYNIMVMDLLGPSLEDLFNMCNR-

TFTISTTLRLGKQILESIESIHSVGFLHRDIKPSNFAMGRFPSTCRKCFMLDFGLA
 |.. |.| .. |... || .|. .|.|||||| || ||.      .... ||||.
KFSLKTVLMIADQMIQRIEYLHNKNFIHRDIKPDNFLMGKLGKNHHQVYIIDFGLS
Kinase TTBK2.AA CK1-G 90-345 32 2.9e-37 123.81 In-house 1-266 (266) Show / Hide 
Range on Protein: 90-345
Range on HMM: 1-266/266
Sequence Identity: 32% (87 aa)

WKVLRKIGGGGFGEIYDALDMLTRENVALKVESAQQPKQVLKMEVAVLKKLQGKD----HVCRFIGCGRNDRFNYVVMQLQGRNLADLRRSQSRGTFTIS
..| .||| | |||..    |.. | || | |  .     |. |    | | |.     .|  |  ||    .|  || | |  | ||     | .|.. 
YRVGKKIGCGNFGELFEGKNMYNNEHVAIKFEPMKSRAPQLHDEYRFYKILNGCPEGIPQVYYFGQCG---KYNIMVMDLLGPSLEDLFDWCDR-KFSVK

TTLRLGKQILESIESIHSVGFLHRDIKPSNFAMGRFPS-TCRKCFMLDFGLARQFTNSCGDVRPP-RAVAGFRGTVRYASINAHRNREMGRHDDLWSLFY
|.. . .|... .| .||   . ||.|| ||  ||  . . .. .. |||.|.|.         | |      || || ||| |  ||  | ||. .|  
TVCMVAIQMIHRMEYVHSHHLIYRDVKPDNFLIGRPSNKDQHVIHIIDFGMAKQYIDPETKQHIPYREHKSLTGTARYMSINTHLGREQSRRDDMEALGH

MLVEFVVGQLPWR-----KIKDK-EQVGSIKERYDHRLMLKH--LPPEFSTFLDHISSLDYFTKPDYQLL
|   |  |.|||        | . . .|  | .     ...   .| .| |.|  . .||.| .|||  |
MFMYFLRGSLPWQGLKADNNKERYQKIGDTKRKTNIEDLCQNNAFPEQFATYLRYVRRLDFFECPDYDYL
Kinase TTBK2.AA CK1-Unique 90-296 26 5.6e-36 122.22 In-house 1-233 (337) Show / Hide 
Range on Protein: 90-296
Range on HMM: 1-233/337
Sequence Identity: 26% (62 aa)

WKVLRKIGGGGFGEIYDALDMLTRE-------NVALK--VESAQQPKQVLKMEVAVLKKLQGKD-------HVCRFIGCGRNDRFNYVVMQLQGRNLADL
|.|  .||.||.|  .  .. . ..         . |  . ..|.. | |. | .|.| .   .       |.|  .  .  .   . ||.. |...  .
WCVIKHIGYGGYGCVH-RVIFVNNGTFRIDDDMYCMKTEQHFMQKHDQRLHIERNVMKFICKCEYQCKYWRHFCEVHDFHQHRDWWWIVMTMHGPSMEEC

RRSQSRGTFTIS------TTLRLGKQILESIESIHSVGFLHRDIKPSNFAMGRFP-STCRKCFMLDFGLARQ--FTNSCGDVRPPRAVAGFRGTVRYASI
..   .  || .      . ...| |.|. ||  | .||.||..|| |.  .  .    .  .|||.|  |   |   .. .|.||  . |||. .|...
CMMMKNFQFTLNEKKNQLCAIQCGYQCLNVIECMHWHGFHHRHMKPNNYCYMAPSQQHQHCYYMLDYGICRRVFFVSNNHQIRQPRPITPFRGCKDYCPC

NAHRNREMGRHDDLWSLFYMLVEFVVGQ--LPWR
  |. || || ||. |.||||.  | .   | |.
SCHQCREHGRRDDMESWFYMLYHLVHNTRGLSWK
Kinase TTBK2.AA Pkinase 90-296 26 4.9e-25 89.61 Pfam 1-213 (293) Show / Hide 
Range on Protein: 90-296
Range on HMM: 1-213/293
Sequence Identity: 26% (58 aa)

WKVLRKIGGGGFGEIYDALDMLTRENVALKVESAQQPKQVLKM------EVAVLKKLQGKDHVCRFIGCGRNDRFNYVVMQLQGRN--LADLR----RSQ
....|||| |.||. | . .  |.. ||.|. . .  |   ..      |....|.| . ....|.... ....  |.|| . .    ..||     . .
YHIGRKIGSGSFGCVYKCHHKGTGKIVAVKIIKKRHEKSWKDQTHRRLSEIQIMKRL-NHPNIVRLYDWFEDKDHIYMVMEYCEGGLYVMDLFDYIST-W

SRGTF--TISTTLRLGKQILESIESIHSVGFLHRDIKPSNFAMGRFPSTCRKCFML-DFGLARQFTNSCGDVRPPRAVAGFRGTVRYASINAHR-NREMG
..|.|  .  .  .  .|||. .| .|| |..|||.||.|. . . . ..  |. . |||||.||        . .   .| || .|..   .| ... |
RHGCFYFSEWECKFYMYQILRGLEYCHSMGIIHRDLKPENILIDNNGHIDA-CVKICDFGLAKQFD-----Y-NNS-MTTFCGTPWYMAPEVIRGGQYYG

RHDDLWSLFYMLVEFVVGQLPWR
.  | ||.  .| |.. |..|..
PKVDMWSCGCILYEMLCGRPPFP
Kinase TTBK2.AA S_TKc 90-349 22 2.8e-20 74.63 SMART 1-231 (231) Show / Hide 
Range on Protein: 90-349
Range on HMM: 1-231/231
Sequence Identity: 22% (62 aa)

WKVLRKIGGGGFGEIYDALDMLTRENVALKVESAQQPKQVLKMEVAVLKKLQGKDHVCRFIGCGRNDRFNYVVMQLQGR---NLADLRRSQSRGT----F
...||||| |.||. | . .  | . ||.|. .     . .. |...|||  . ......... ..  . |.|| . .    .| |. ... |.     |
YEILRKIGKGAFGKVYKCRHKKTGRIVAIKIIK-----EHIRREIQILKK--HHPNIVKLYDVFQD-DHLYMVMEYCDGDLGDLFDYIKKRGRHGLRFPF

TISTTLRLGKQILESIESIHSVGFLHRDIKPSNFAMGRFPSTCRKCFMLDFGLARQFTNSCGDVRPPRAVAGFRGTVRYASINAHRNREMGR-HDDLWSL
.  .. .. .||.. .| .|| |..|||.||.|  . .           |||||||.               | ||  | .         |.   | ||.
PE-HARFYMYQICCALEYCHSHGIIHRDLKPENILLDE------HIKICDFGLARQL-------------TTFCGTPWYMAPEVL---GYGKCKCDWWSC

FYMLVEFVVGQLPWRKIKDKEQVGSIKERYDHRLMLKHLPPEFSTFLDHISSLDYF--TKPDYQLL-------TSVF
  .| |...|. |..   ...    |.            .||.  |....   |          |           |
GCILYEMLCGYPPFP--QMQMMFKKIG------------SPEAKDFIRKCLQKDPEKRPTA-EALQDEWDIKCHPWF
Kinase TTBK2.AA CK1-Unclassified 257-299 60 2.3e-13 35.83 In-house 178-220 (244) Show / Hide 
Range on Protein: 257-299
Range on HMM: 178-220/244
Sequence Identity: 60% (26 aa)

GTVRYASINAHRNREMGRHDDLWSLFYMLVEFVVGQLPWRKIK
|| ||||||||.  | .| ||| || | |. |  |.|||  ||
GTARYASINAHLGIEQSRRDDLESLGYVLIYFLKGSLPWQNIK
Kinase TTBK2.AA TyrKc 90-334 16 2.1e-07 -102.84 SMART 1-280 (280) Show / Hide 
Range on Protein: 90-334
Range on HMM: 1-280/280
Sequence Identity: 16% (48 aa)

WKVLRKIGGGGFGEIYDALDMLTRENVALKVESAQQPKQVLKMEVAVLKKL-QGKDHVCRFIGCGRND-------RFNYVVMQL-QGRNLADLRRSQSRG
 . ..|.| | |||.| .  ... ..|| |.  .   .. .  |  ...||    ... |..|. . .          ..|| .  . .| |  |.  . 
ITLGKKLGEGAFGEVYKG--TWK-IQVAVKMLKEDA-REDFMREARIMCKLGGHHPNIVRLYGVCTQQGRNFMYIEPLMIVMEYMPHGDLKDYLRKHRPK

TFTISTTLRLGKQILESIESIHSVGFLHRDIKPSNFAMGRFPSTCRKCFMLDFGLARQFTNS--CGDVRPPRAVA----GFR--GTVRYASINAHRNREM
 .. .. |    || .  | .|| .. |||.   |   |.       .   ||||.|  ..   .| ..    ..    | .    .|  .. . . .. 
-LCMKDLLSFCWQIACGMEYLHSKNCIHRDLAARNCLVGENH----TVKISDFGLSRDIYDDDQQG-ESKDYYRKKEHKGGKTMLPIRWMAPECINYGKF

GRHDDLWS-------LFYMLVEFVVGQ----LPWRKIKDKEQVGSIKERYDH--------------RLMLKHLPPEFS---TFLDHISSL
    | ||       .|    .   |.    .... .  . . |   .. ..              ..|..    . .   || . .. .
TTKSDVWSFGVCMWEIFTYGQQPYPGMIQQMMSNQEVIEYVKQGYRMPQPPNDYPMSFVCCPDEMYQIMKQCWHEDPEDRPTFSEIHECF