VRK1

Species: Mouse
Alias: Vrk1, VRK1
External Links: MGI , Entrez Gene , Refseq cDNA , Refseq Protein , Phosphosite , iHOP
Annotation:

Classification

Group: CK1
Family: VRK

Sequence

Name Sequence Type Origin Length Description Download
VRK1.AA Protein Sugen 440 None Fasta, JSON
VRK1.NA RNA Sugen 1694 None Fasta, JSON
VRK1.kin_dom Protein Kinase Domain Sugen global kinase HMM prediction 267 Kinase domain by global Sugen HMM Fasta, JSON

Protein domain

Protein domains of VRK1.AA. The domains are annotated by HMM profiles from Pfam and SMART, as well as in-house data which includes HMMs of each individual kinase group, family and subfamily. Here is domain list in details, including sequence identity, significance and alignment. In particular, you can find can find the best hit kinase group/family/subfamily, which is helpful to understand the relationship between kinases.Kinase domain and best hit kinase group/family/subfamily are highlighted in red and blue. Visualized by pviz.

Usage: Zoom in selected region by dragging mouse and zoom out by double-clicking.

Domain Protein name Domain Name Range Identity (%) Significance Score Profile Source Profile Range (length) Alignment
Kinase VRK1.AA VRK 37-303 65 2.5e-214 691.97 In-house 1-284 (284) Show / Hide
Range on Protein: 37-303
Range on HMM: 1-284/284
Sequence Identity: 65% (185 aa)

WKLGLPIGQGGFGCIYLADTNSSKPVGSDAPCVVKVEP-SDNGPLFTELKFYQRAAKPEQIQKWIRTHK------------LKYLGVPKYWGSGLHDKNG
|.||.|||||||||||||..|..||...||..|||.|| ..|||||||..||||||||||||||...||            |..||.|..||.|.||.||
WRLGKPIGQGGFGCIYLASPNTCKPCEKDAQYVVKIEPPHENGPLFTEMHFYQRAAKPEQIQKWMKKHKSLPAPQTHVLSRLPWLGIPYCWGFGYHDFNG

KSYRFMIMDRFGSDLQKIYE-ANAKRFSRKTVLQLSLRILDILEYIHEHEYVHGDIKASNLLLSH-KNPDQVYLVDYGLAYRYCPDGVHKEYKEDPKRCH
..||||.|.|||.||||||| .|..|||.||||||..|.||.|||.||.|||||||||.|.||.. |||||||||||||||||||.|.|..|||||.|||
EKYRFMVMPRFGRDLQKIYEDQNGHRFSMKTVLQLACRMLDVLEYLHENEYVHGDIKAANILLGFEKNPDQVYLVDYGLAYRYCPNGKHRQYKEDPRRCH

DGTLEFTSIDAHKGVAPSRRGDLEILGYCMIQWLSGCLPWEDNLK--DPNYVRDSKIRYRDNVAALMEKCFPEKNKPGEIAKYM
.||.||||.|||||.|||||.|||||||||..|| |.|||.|.|.  ||..|.|.|....||....|.||||.|....||.|||
NGTCEFTSMDAHKGCAPSRRSDLEILGYCMMMWLYGYLPWMDCLQQQDPEKVQDAKQKFMDNIPEMMQKCFPWKQVCCEIGKYM

Kinase VRK1.AA CK1 37-320 24 3.2e-87 296.08 In-house 1-339 (339) Show / Hide
Range on Protein: 37-320
Range on HMM: 1-339/339
Sequence Identity: 24% (84 aa)

WKLGLPIGQGGFG-CIYLADTN--SSKPVG---SDAPCVVKVEPSD-NGPLFTELKFYQRAAKPEQIQKWIR----THKLKY---LGVPKYWGSGLHDKN
||.. .||.|||| .||... .  .... .   ..  ...|||| . .|........||. .|.....|| .    .||...   .|.|     . | ..
WKVVKKIGEGGFGYQIYKVQKEDHKDMKNNKPYKGEEYAMKVEPKKSMGQHPQLMEEYQMYKKLQGGKKW-KASILKHKHFCKKHCGCPHPCMYWYHGEE

GKSYRFMIMDRFGSDLQKIYE---ANAKRFSRKTVLQLSLRILDILEYIHEHEYVHGDIKASNLLLSH--------------KNPDQVYLVDYGLAY-RY
.. |..|.|...| .|... .    . ..|| ||.|.. ...|. |||.|.. ..| |||..|....               .. .|||..|.|.|  .|
DDYYNYMVMTLLGPNLEDLRKQNRMCNRKFSMKTWLMIAIQMLEALEYMHDCGFIHRDIKPDNFCMGRNESFKYGKHHHEWNNEHRQVYMIDFGMARRKY

CPDGVHK----------EYKEDP----KRCHDG-TLEFTSIDAHKGVAPSRRGDLEILGYCMIQWLSGC--LPWEDNLK-----DPNYVRDSKIRYRDNV
.... |.          .... .    |. . | |....||..|.|. ..|| ||. ..|..| || |.  ||| .  .     |.. |.. |  ..|. 
RDKDGHNRWNGPRDKTWQHRPPREHKKKKGFRGCTARYCSINCHLGKEQGRRDDLWSWFYMLIEWLKGTPGLPWQNMKDEMKPKDHQ-VEKMKYEFIDEK

AALMEKCFPEKN-----KPGEIAKYMESVKLLEYTEKPLYQNL
  ..  .   ..      | |  |.|. .. |.| ..| |...
KMSTPFF-LCCPKKDHDCPQEF-KIMKYIRSLKYYDRPDYEMI

Kinase VRK1.AA CK1-A 122-320 33 5.4e-31 106.69 In-house 65-261 (261) Show / Hide
Range on Protein: 122-320
Range on HMM: 65-261/261
Sequence Identity: 33% (67 aa)

NGKSYRFMIMDRFGSDLQKIYEANAKRFSRKTVLQLSLRILDILEYIHEHEYVHGDIKASNLLLS-HKNPDQVYLVDYGLA--YRYCPDGVHKEYKEDPK
..| |  |.||  |  |  ..    .||. |||| |   ..  .||.||. ..| |||  | |.   .   ...|.|.|||  ||      | .|.||  
CEKDYNVMVMDLLGPSLEDLFNFCKRRFTMKTVLMLADQMIMRIEYVHEKNFIHRDIKPDNFLMGIGRHCNKLFLIDFGLAKKYRDSRTRQHIPYRED--

RCHDGTLEFTSIDAHKGVAPSRRGDLEILGYCMIQWLSGCLPWEDNLKDPNYVRDSKIRYRDNVAALMEKCFPEKNKPGEIAKYMESVKLLEYTEKPLYQ
.   ||  . ||.|| |.  ||| |.| .||.|. .  | |||          .  ||  .   ... . |   |  | | . ||. .. | . |.| | 
KNLTGTARYASINAHLGIEQSRRDDMESMGYVMMYFNRGKLPWQGMKAMTKKQKYEKISEKKMSTPIEQLC---KGFPAEFCMYMNYCRNLRFEEQPDYM

NL
 |
YL

Kinase VRK1.AA CK1-D 126-320 33 2.7e-29 100.41 In-house 69-261 (261) Show / Hide
Range on Protein: 126-320
Range on HMM: 69-261/261
Sequence Identity: 33% (66 aa)

YRFMIMDRFGSDLQKIYEANAKRFSRKTVLQLSLRILDILEYIHEHEYVHGDIKASNLLLS-HKNPDQVYLVDYGLAYRYCPDGVHKEYKEDPKRCHDGT
|  |.||  |  |  ..    ..|| |||| |.. ..  .|||| ....| |||  | |.   |  . ||..|.||| ||     |.      ..   ||
YNVMVMDLLGPSLEDLFNYCHRKFSLKTVLMLADQMICRIEYIHCRNFIHRDIKPDNFLMGLGKRGNMVYIIDFGLAKRYRDARTHQHIPYRENKNLTGT

LEFTSIDAHKGVAPSRRGDLEILGYCMIQWLSGCLPWE---DNLKDPNYVRDSKIRYRDNVAALMEKCFPEKNKPGEIAKYMESVKLLEYTEKPLYQNL
  . ||  |.|.  ||| ||| ||| .. .  | |||       |   | | .  .   ..  |  | .|.     | ..||. .. |.. .|| |  |
ARYASINTHQGIEQSRRDDLESLGYVLMYFNRGSLPWQGLKAATKRQKYERICEKKMSTKIDTLC-KGYPS-----EFQQYMNYCRNLKFDDKPDYCYL

Kinase VRK1.AA CK1-Unclassified 126-261 40 1.1e-25 72.82 In-house 78-216 (244) Show / Hide
Range on Protein: 126-261
Range on HMM: 78-216/244
Sequence Identity: 40% (57 aa)

YRFMIMDRFGSDLQKIYEANAKRFSRKTVLQLSLRILDILEYIHEHEYVHGDIKASNLLL--SHKNPDQVYLVDYGLAYRYC---PDGVHKEYKEDPKRC
| .|.||  |..| ..     ..|| |||| .   ... .||.|.. ..| |||  | |   . || .|||..|.||. ||     .| | .|.|  .. 
YNIMVMDLLGPSLEDLFNMCNRKFSLKTVLMIADQMIQRIEYLHNKNFIHRDIKPDNFLMGKLGKNHHQVYIIDFGLSKRYIDMDKTGKHIPYRE--NKN

HDGTLEFTSIDAHKGVAPSRRGDLEILGYCMIQWLSGCLPW
  ||  ..|| ||.|.  ||| ||| |||..|  | | |||
LTGTARYASINAHLGIEQSRRDDLESLGYVLIYFLKGSLPW

Kinase VRK1.AA CK1 126-261 37 5e-25 83.22 In-house 79-216 (271) Show / Hide
Range on Protein: 126-261
Range on HMM: 79-216/271
Sequence Identity: 37% (53 aa)

YRFMIMDRFGSDLQKIYEANAKRFSRKTVLQLSLRILDILEYIHEHEYVHGDIKASNLLLSH--KNPDQVYLVDYGLAYRY--CPDGVHKEYKEDPKRCH
| .|.||  | .| . .    ..|| |||| .   ... .||.|.. ..| |||  | |     |. .|||..|.||| ||    .. | .|.|  ..  
YNIMVMDLLGPSLEDLFNFCNRKFSLKTVLMIADQMIQRIEYVHNKNFIHRDIKPDNFLMGRYGKHCHQVYIIDFGLAKRYRDDKTHQHIPYRE--NKNL

DGTLEFTSIDAHKGVAPSRRGDLEILGYCMIQWLSGCLPW
 ||  ..|| .| |.  ||| |.| |||...  | | |||
TGTARYASINTHLGIEQSRRDDMESLGYVLMYFLRGSLPW

Kinase VRK1.AA CK1-G 126-320 30 6.4e-25 81.33 In-house 70-266 (266) Show / Hide
Range on Protein: 126-320
Range on HMM: 70-266/266
Sequence Identity: 30% (63 aa)

YRFMIMDRFGSDLQKIYEANAKRFSRKTVLQLSLRILDILEYIHEHEYVHGDIKASNLLL---SHKNPDQVYLVDYGLA--YRYCPDGVHKEYKEDPKRC
|  |.||  |  |   ..    .|| |||....  ... .||.|.|. . .|.|  | |    | |..  ....|.|.|  |. .  . |  | |  .. 
YNIMVMDLLGPSLEDLFDWCDRKFSVKTVCMVAIQMIHRMEYVHSHHLIYRDVKPDNFLIGRPSNKDQHVIHIIDFGMAKQYIDPETKQHIPYRE--HKS

HDGTLEFTSIDAHKGVAPSRRGDLEILGYCMIQWLSGCLPWE----DNLKDPNYVRDSKIRYRDNVAALMEK-CFPEKNKPGEIAKYMESVKLLEYTEKP
  ||  . ||  | |   ||| |.| ||   .  | | |||     ||.|   | .  . . . |. .|..   |||     ..|.|.. |  |.. |.|
LTGTARYMSINTHLGREQSRRDDMEALGHMFMYFLRGSLPWQGLKADNNKE-RYQKIGDTKRKTNIEDLCQNNAFPE-----QFATYLRYVRRLDFFECP

LYQNL
 |  |
DYDYL

Kinase VRK1.AA TTBKL 124-324 25 6.7e-16 50.23 In-house 72-288 (288) Show / Hide
Range on Protein: 124-324
Range on HMM: 72-288/288
Sequence Identity: 25% (56 aa)

KSYRFMIMDRFGSDLQKIYEANAKR--FSRKTVLQLSLRILDILEYIHEHEYVHGDIKASNLLLSHK---NPD--QVYLVDYGLAYRYC-PDGVH----K
|.|.||.|   | .||...  .  .  ||. |.. .. ..|. | ..|.. ..| |.| .|  .  .   ...   |||.|.|.| .|  .||      .
KDYNFMVMTLCGPNLQDLRKMMPNKKRFSDGTWSRIGIQCLYALKQMHDCGFIHRDVKPCNCCWGYHDHSCERCRHVYLIDFGMARQYAWKDGEWNGPIH

EYKEDPKRCHD--------GTLEFTSIDAHKGVAPSRRGDLEILGYCMIQWLSGCLPWEDNLKDPNYVRDSKIRYRDNVAALMEKCFPEKNKPGEIAKYM
| |   .|  .        ||. ..|...| .   .|  ||  . | .|  . | |||. |..|.  .   |    |..  |. ... ..  | | .| |
ENKWMMRRPRNFRHKAPFRGTTRYCSPNMHDRKEQGRHDDLWSWMYMIIELHCG-LPWT-NMEDKMEIEHMKKNMKDED--LFKDMPRDHDCPSEFCKFM

ESVKLLEYTEKPLYQNLRDIL
. .. |.| . | |. .. ..
KHLRSLRYYDRPDYEMIYECF

Kinase VRK1.AA Worm6 126-320 24 4.1e-14 47.29 In-house 77-279 (279) Show / Hide
Range on Protein: 126-320
Range on HMM: 77-279/279
Sequence Identity: 24% (50 aa)

YRFMIMDRFGSDLQKIYEANA-KRFSRKTVLQLSLRILDILEYIHEHEYVHGDIKASNLLLSH------KNPDQVYLVDYGLAY--RYCPDGV--HKEY-
.....|  .| .|. . .. . ..||  | |....  |. .|  | . ..| |.|..|           ..  ..|..|.|..   .|| .|   ..   
FNYIVMTLVGKNLWDLRKNRPDRKFSMGTGLKIAIQCLEAIEDLHNCGFIHRDVKPGNFCIGRYQMKEDNEHHTIYMLDFGMCRRKKYCNKGNELRTPRW

KEDPKRCHDGTLEFTSIDAHKGVAPSRRGDLEILGYCMIQWLSGCLPWEDNLKDPNYVRDSKIRYRDNVAALMEKCFPEKNKPG-EIAKYMESVKLLEYT
.. . |   ||. . .. .|||   .|. |.|   | |. ...|||||  ..||.. | . | . |..  | |...| . . |  |  . |. .  . | 
TACGFR---GTVRYAPLACHKGQEQCRKDDCESWFYMMVEMIVGCLPWR-HMKDHDHVEKHKKWCRRRTRAPMMRMFFG-PCPKEEFNDIMDYIDQYSYW

EKPLYQNL
..| |...
DRPDYKFI

Kinase VRK1.AA S_TKc 37-342 13 5.4e-12 -0.99 SMART 1-231 (231) Show / Hide
Range on Protein: 37-342
Range on HMM: 1-231/231
Sequence Identity: 13% (44 aa)

WKLGLPIGQGGFGCIYLADTNSSKPVGSDAPCVVKVEPSDNGPLFTELKFYQRAAKPEQIQKWIRTHKLKYLGVPKYWGSGLHDKNGKSYRFMIMDRFGS
.... .||.|.||. |..  ..     ..  . .|. .                   |.|.. |. .| .   . |. ..  .     .. .|.|.  . 
YEILRKIGKGAFGKVYKCRHKK-----TGRIVAIKIIK-------------------EHIRREIQILKKHHPNIVKLYDVFQD-----DHLYMVMEYCDG

---DLQKIYEANAKR-----FSRKTVLQLSLRILDILEYIHEHEYVHGDIKASNLLLSHKNPDQVYLVDYGLAYRYCPDGVHKEYKEDPKRCHDGTLEFT
   || .. . . ..     |.  ..  .   |.. |||.|.|  .| |.| .|.||..    .. . | ||| ..               |  ||... 
DLGDLFDYIKKRGRHGLRFPFPE-HARFYMYQICCALEYCHSHGIIHRDLKPENILLDE----HIKICDFGLARQL------------TTFC--GTPWYM

SIDAHKGVAPSR-RGDLEILGYCMIQWLSGCLPWEDNLKDPNYVRDSKIRYRDNVAALMEKCFPEKNKPGEIAKYMESVKLLEYTEKPLYQNLRDILLQG
.         .. . |   .| ...  |.|. |..                  .......|.                            . ..|.. . 
APEVL---GYGKCKCDWWSCGCILYEMLCGYPPFP------------------QMQMMFKKIG--------------------------SPEAKDFIRKC

LKA-----IGSKDDGK-------LDFS
|.      ..  .  .         . 
LQKDPEKRPTA-EALQDEWDIKCHPWF

Kinase VRK1.AA TTBK 223-320 31 6.7e-08 24.03 In-house 169-257 (257) Show / Hide
Range on Protein: 223-320
Range on HMM: 169-257/257
Sequence Identity: 31% (31 aa)

GTLEFTSIDAHKGVAPSRRGDLEILGYCMIQWLSGCLPWEDNLKDPNYVRDSKIRYRDNVAALMEKCFPEKNKPGEIAKYMESVKLLEYTEKPLYQNL
||  . || ||.     |. ||  | | ..  . | |||   .|| . |   | .|  .   |.. |      | |.  .|. .| |.| ..| || .
GTVRYASINAHRNREMGRHDDLWSLFYMLVEFVQGQLPWR-KIKDKDQVGEMKEKY--DHRMLLKHC------PHEFHQFMDHIKSLNYEDRPDYQLI

Kinase VRK1.AA TTBK 149-204 37 9.8e-07 19.86 In-house 94-151 (257) Show / Hide
Range on Protein: 149-204
Range on HMM: 94-151/257
Sequence Identity: 37% (22 aa)

FSRKTVLQLSLRILDILEYIHEHEYVHGDIKASN--LLLSHKNPDQVYLVDYGLAYRY
||  | |.| . ||. .| ||.  . | ||| ||  . .  ..  ..|..|.||| .|
FSLSTTLRLGVQILQSIESIHSVGFLHRDIKPSNFAMGRNPSTCRKCYMLDFGLARQY

Kinase VRK1.AA Worm6 37-60 45 0.000113 13.08 In-house 1-24 (279) Show / Hide
Range on Protein: 37-60
Range on HMM: 1-24/279
Sequence Identity: 45% (11 aa)

WKLGLPIGQGGFGCIYLADTNSSK
||.. .||.|||| .|..   | |
WKVTKKIGEGGFGAVYKVEDKSDK

Kinase VRK1.AA TyrKc 37-303 14 0.00017 -149.93 SMART 1-280 (280) Show / Hide
Range on Protein: 37-303
Range on HMM: 1-280/280
Sequence Identity: 14% (48 aa)

WKLGLPIGQGGFGCIYLADTNSSKPVGSDAPCVVKVEPSDNGPLFTELKFYQRAAKPEQIQKWIR-THKLKYLG-----VPKYWGSGLHDKN-----GKS
 .||  .| | || .|..  .         .. ||.  .|                   ..  .|    .. ||     . .  |  ....      .  
ITLGKKLGEGAFGEVYKGTWK--------IQVAVKMLKEDA------------------REDFMREARIMCKLGGHHPNIVRLYGVCTQQGRNFMYIEPL

YRFMIMDRFGSDLQKIYEANAKRFSRKTVLQLSLRILDILEYIHEHEYVHGDIKASNLLLSHKNPDQVYLVDYGLAYRYCPD---GVHKEYKE-----DP
.  |     | ||..   .. .... |. |. .. | .  ||.|.. ..| |. | | |.....  .|   | ||.     |   |. |.|.      . 
MIVMEYMPHG-DLKDYLRKHRPKLCMKDLLSFCWQIACGMEYLHSKNCIHRDLAARNCLVGENH--TVKISDFGLSRDIYDDDQQGESKDYYRKKEHKGG

K------------------------------------RCHDGTLE-----FTSIDAHKGVAPSRRGDLEILGYCMIQWLSGCLPWEDNLKDPNYVRDSKI
|                                    ..     .      . ..... |   .| .    .|     .|                 .  
KTMLPIRWMAPECINYGKFTTKSDVWSFGVCMWEIFTYGQQPYPGMIQQMMSNQEVIEYVKQGYRMPQPPNDY---P-MS-----------------F-V

RYRDNVAALMEKCFPEKNKP----GEIAKYM
.  | .  .|..|  |. .      || ...
CCPDEMYQIMKQCWHEDPEDRPTFSEIHECF

Kinase VRK1.AA TTBK 37-52 62 0.000555 10.0 In-house 1-16 (257) Show / Hide
Range on Protein: 37-52
Range on HMM: 1-16/257
Sequence Identity: 62% (10 aa)

WKLGLPIGQGGFGCIY
||    ||.|||| ||
WKVVKKIGGGGFGEIY

Kinase VRK1.AA CK1 37-54 55 0.000596 9.72 In-house 1-18 (271) Show / Hide
Range on Protein: 37-54
Range on HMM: 1-18/271
Sequence Identity: 55% (10 aa)

WKLGLPIGQGGFGCIYLA
 ..|  |||| || |||.
YRVGRKIGQGSFGDIYLG

Kinase VRK1.AA CK1-Unclassified 37-54 44 0.000727 7.31 In-house 1-18 (244) Show / Hide
Range on Protein: 37-54
Range on HMM: 1-18/244
Sequence Identity: 44% (8 aa)

WKLGLPIGQGGFGCIYLA
 ...  |||| || ||..
YRVIEKIGQGSFGEIYKC

Kinase VRK1.AA CK1 293-318 37 0.001109 8.78 In-house 245-271 (271) Show / Hide
Range on Protein: 293-318
Range on HMM: 245-271/271
Sequence Identity: 37% (10 aa)

KN-KPGEIAKYMESVKLLEYTEKPLYQ
|.  | | | |.. .. |.. ||| |.
KGNFPNEFAMYLNYCRQLHFEEKPDYM

Kinase VRK1.AA Pkinase 124-201 28 0.004643 11.9 Pfam 72-159 (293) Show / Hide
Range on Protein: 124-201
Range on HMM: 72-159/293
Sequence Identity: 28% (25 aa)

KSYRFMIMDRF-GS----DLQKIYE-ANAKRF--SRKTVLQLSLRILDILEYIHEHEYVHGDIKASNLLLSHKNPDQ---VYLVDYGLA
|..  |.|.   |     ||  . .  . ..|  | ...    . ||  |||.|..  .| |.| .|.|.. .|..    | . | |||
KDHIYMVMEYCEGGLYVMDLFDYISTWRHGCFYFSEWECKFYMYQILRGLEYCHSMGIIHRDLKPENILID-NNGHIDACVKICDFGLA

Kinase VRK1.AA TTBKL 37-54 44 0.011969 4.85 In-house 1-18 (288) Show / Hide
Range on Protein: 37-54
Range on HMM: 1-18/288
Sequence Identity: 44% (8 aa)

WKLGLPIGQGGFGCIYLA
|.    ||.|||| .|..
WMIVKMIGEGGFGQVYHV

Kinase VRK1.AA CK1-A 37-54 50 0.022535 3.99 In-house 1-18 (261) Show / Hide
Range on Protein: 37-54
Range on HMM: 1-18/261
Sequence Identity: 50% (9 aa)

WKLGLPIGQGGFGCIYLA
..|  .|| | || |||.
YRLVRKIGSGSFGDIYLG

Kinase VRK1.AA CK1-D 37-53 47 0.028571 3.62 In-house 1-17 (261) Show / Hide
Range on Protein: 37-53
Range on HMM: 1-17/261
Sequence Identity: 47% (8 aa)

WKLGLPIGQGGFGCIYL
...|  || | || ||.
YRIGRKIGSGSFGDIYH

Kinase VRK1.AA Pkinase 37-54 44 0.062412 7.91 Pfam 1-18 (293) Show / Hide
Range on Protein: 37-54
Range on HMM: 1-18/293
Sequence Identity: 44% (8 aa)

WKLGLPIGQGGFGCIYLA
...| .||.|.||| |..
YHIGRKIGSGSFGCVYKC

Kinase VRK1.AA CK1-G 37-53 35 0.249331 0.16 In-house 1-17 (266) Show / Hide
Range on Protein: 37-53
Range on HMM: 1-17/266
Sequence Identity: 35% (6 aa)

WKLGLPIGQGGFGCIYL
.. |  || | || ...
YRVGKKIGCGNFGELFE