Gene aSWK440 (Nematode worm)

aSWK440

Species: Nematode worm
Alias: CE28786, Y105E8B.3, aSWK440
External Links: Wormbase Link ,
Annotation: WormBase Physical Map location: I: 14660153-14665107, WormBase Genetic Map location: I:25.6,

Classification

Group: Atypical
Family: RIO
Subfamily: RIO2

Sequence

Name Sequence Type Origin Length Description Download
aSWK440.AA Protein Sugen 529 None Fasta, JSON

Protein domain

Protein domains of aSWK440.AA. The domains are annotated by HMM profiles from Pfam and SMART, as well as in-house data which includes HMMs of each individual kinase group, family and subfamily. Here is domain list in details, including sequence identity, significance and alignment. In particular, you can find can find the best hit kinase group/family/subfamily, which is helpful to understand the relationship between kinases.Kinase domain and best hit kinase group/family/subfamily are highlighted in red and blue. Visualized by pviz.

Usage: Zoom in selected region by dragging mouse and zoom out by double-clicking.

Show/hide domain list
Domain Protein name Domain Name Range Identity (%) Significance Score Profile Source Profile Range (length) Alignment
Kinase aSWK440.AA RIO2 73-308 48 4.7e-134 451.66 In-house 1-260 (260) Show / Hide 
Range on Protein: 73-308
Range on HMM: 1-260/260
Sequence Identity: 48% (126 aa)

YRLTIRGYDYLALRALCSREVVGSVGNQIGIGKESDVYVGGDPELNDLCLKFHRLGRTSFRKIKEKRDYHKKRKSASWLYLSRLAAAKEFAFLKALQERG
||||  |||||||. | || || |||||.|.|||||.|   . . |   .||||||||||. || .|||||.| ..||.|||||.| ||..| ..| .|.
YRLTNAGYDYLALKTLSSRQVVYSVGNQMGVGKESDIYKCSNENGNQFIMKFHRLGRTSFHNIKNNRDYHKHRHQYSWMYLSRLSAMKEYQFMDMLYKRN

FPVPKAVDVCRHLVVMQLVVGQTLCNVTHVEDAGALYDRLMALIVKMARHGVIHGDFNEFNLIMLEDER------IVMIDFPQMVSIDHPNAEYYFDRDV
||||| .|  || ||| |. |  .|.  |...   .|| .| .||..| || ||.|||||||.  .  .      ..|||||||||. |.||..||||||
FPVPKPIDYNRHIVVMELINGYPMCQIHHHDNPPYVYDQCMCFIVRLANHGLIHCDFNEFNLMIDDNDHDENDCGFIMIDFPQMVSTQHQNAQWYFDRDV

TCVRTFFKRKFDYESEDWP------------------KFDEVERKGNMDVLLEASGFTKK
 |.. ||...| ||..  |                   |  . |  ..|..  ||||.||
DCIHRFFMKRFNYEPKPFPSMLDTEGFGDGYKYAYPDFFRDIQRTDTLDEEVQASGFNKK
Kinase aSWK440.AA RIO 73-301 31 7.2e-99 334.77 In-house 1-276 (276) Show / Hide 
Range on Protein: 73-301
Range on HMM: 1-276/276
Sequence Identity: 31% (86 aa)

YRLTIRGYDYLALRALCSREVVGSVGNQIGIGKESDVYVGGDPELN-----------DLCLKFHRLGRTSFRKIKEKRD---YHKKRKS-ASWLYLSRLA
|..|. .|.....  . .| .| ||||.||.|||||.|   . . .              .|.||.|||||. .| .||   |.|.| . ..|.|..||.
YEQTNDPYTRMIMYKMVNRGMVESVGNCIGVGKESDIYHCSNENGEDEKEDSKVIPTECAIKIHRTGRTSFKDRKKYRDGEFYFKHRHCKHNWRYMHRLW

AAKEFAFLKALQERGFPVPKAVDVCRHLVVMQLVVG-------QTLCNVTHVEDAGALYDRLMALIVKMARHG-VIHGDFNEFNLIMLEDER------IV
| ||....|.|...|||.|. .|. || .|| .  .         .|.  ..|.   .|. .|....... |.  .|.||||||..  ..        ..
AEKEMRNMKRLYQSGFPCPEPIDYKRHVLVMEFINHDQMPAPKYPMCQIHEHENMKHVYHQCMCYMRRLYQHCRLVHCDFNEFNMMWHDGKHDENDCGFY

MIDFPQMVSIDHPNAEYYFDRDVTCVRTFFKRKFDYESEDWPKFDEVE------------------RKGNMDVLLE
||||||||..|||.|..||.||. ||. ||...| ||..  . . ...                  |  . |.. .
MIDFPQMVEHDHPHALWYFRRDCKCVNMFFMKRFVYEPFPEREMFDFVGFGDGYKYAYPDFKRDVKRTDTLDHENM
Kinase aSWK440.AA RIO1 108-287 30 1.7e-73 229.63 Pfam 1-200 (200) Show / Hide 
Range on Protein: 108-287
Range on HMM: 1-200/200
Sequence Identity: 30% (61 aa)

DVYVGGD-PELN-DLCLKFHRLGRTSFRKIKEKRDYHKK----RKSASWLYLSRLAAAKEFAFLKALQERGFPVPKAVDVCRHLVVMQLVV---GQTLCN
.||.. . .. .  ...|..|.|.|.|.|.|..|||..     .   .|.|..|..| |||..||...|.|.|.||..|. || .|| ..    |  ...
NVYHAYSMEDGKDECAVKIYRTGTTCFKKMKRYRDYDFRFRHRYHHHNWRYMVRMWAEKEFRNLKRMYEAGVPCPKPIDWNRHVLVMEFIGDKDGWPAPR

VTHVE--------DAGALYDRLMA--LIVKMARHGVIHGDFNEFNLIMLEDERIVMIDFPQMVSIDHPNAEYYFDRDVTCVRTFFKRKFDYE-SEDWPKF
. .||        .|  .|| ..   ........|..|||..|.|... .|. ...||.||.|..|||.|. ...||.... .||.||. .| ..| ...
LKDVEMELELSEEEAEEIYDEIIREYMRRMYQECGLVHGDLSEYNILVHDDGKPWIIDWPQAVEHDHPHALEFLERDCRNIINFFRRKGVDERVMDFREI
RIO aSWK440.AA RIO 66-289 23 4.2e-54 186.96 SMART 1-253 (253) Show / Hide 
Range on Protein: 66-289
Range on HMM: 1-253/253
Sequence Identity: 23% (60 aa)

RSKKFDGYRLTIRGYDYLALRALCSREVVGSVG--NQIGIGKESDVYVG-G---DPELNDLCLKFHRLGRTSFRKIKEKRDYHKKRK----SASWLYLSR
 ......|.... ......|...  | .. ...  ..|. |||..||.. |   |.. |.   |..|...|.|..... ...... |     ..|....|
DKEDYATYEEVFDPRTRMTLYKMVNRGYIEEINNHGCISTGKEANVYHAMGGDFDKNGNECAVKIYRTSTTEFKRMWRYIQGDFRFKHGYHHINWRKMVR

LAAAKEFAFLKALQERGFPVPKAVDVCRHLVVMQLVVG-----QTLCNVTHVEDAGA----LYDRLMALIVKMARHG-VIHGDFNEFNLIML-----EDE
|.| ||| .|. ..| |.|.||.... || .|| ....      .| .|.  |  .     .|. .|  ..||.. .  .|.|..|.|..       .|.
LWAEKEFRNLQRMYEAGVPCPKPIAWRRHVLVMEFIGDDGWPAPRLKDVEWEEWEMDFKWEYYWQIMEYMRKMYHECHLVHADLSEYNMLYHDLEDENDC

RIVMIDFPQMVSIDHPNAEYYFDRDVTCVRTFFKRKFDYES----EDWPKFDE
 ...||..| |..||| ..... ||......||.||  ..     |.. .. .
KVWIIDWSQSVECDHPMWLEFLERDIWNIINFFRRKGVDCDDIYREIFERITG
Rio2_N aSWK440.AA Rio2_N 9-91 53 1.3e-41 142.74 Pfam 1-84 (84) Show / Hide 
Range on Protein: 9-91
Range on HMM: 1-84/84
Sequence Identity: 53% (45 aa)

MRYLEGDHFRVLIAVEMGMKNHEVVPLALVSAIAGIH-RGGVARTLNDLCKHSLVAFERSKKFDGYRLTIRGYDYLALRALCSR
||||. ..||||.||||||.|||.||  |.  |.... .||. . | .|||| |.. .. ||.||||||  |||||||... .|
MRYLSKEDFRVLTAVEMGMRNHEWVPTELIHQISRLRSHGGCHYRLSRLCKHKLISHVQNKKYDGYRLTYGGYDYLALHTFVKR
Kinase aSWK440.AA RIO1 225-276 28 5.5e-05 13.35 In-house 165-215 (225) Show / Hide 
Range on Protein: 225-276
Range on HMM: 165-215/225
Sequence Identity: 28% (15 aa)

IHGDFNEFNLIMLEDERIVMIDFPQMVSIDHPNAEYYFDRDVTCVRTFFKRK
.|.|  |.|..   .. . |||  | |  ||| .  .  .|.  |  .|...
VHADLSEYNMLYH-NDKLYMIDVSQSVEHDHPHSLEFLRMDCKNVNMYFMKH
Kinase aSWK440.AA RIO3 155-275 25 0.000182 10.23 In-house 101-227 (254) Show / Hide 
Range on Protein: 155-275
Range on HMM: 101-227/254
Sequence Identity: 25% (32 aa)

RLAAAKEFAFLKALQERGFPVPKAVDVCRHLVVMQLVVGQTL-------CNVTHVEDAGALYDRLMALIVKMARHGVIHGDFNEFNLIMLEDERIVMIDF
|. | ||   |  .|  | |.|  | . .|..|| ..  . .         .   |   | |. |  .        ..| |. |.|..     .. .|| 
RMWAEKEMHNLARMQRAGIPCPTVVLLKKHILVMSFIGHDQVPAPKLKEVKLNSEEMKEAYYQTLHLMRQLYHECTLVHADLSEYNMLW-HAGKVWLIDV

PQMVSIDHPNAEYYFDRDVTCVRTFFKR
 | |   ||    .. ||.  |  ||..
SQSVEPTHPHGLEFLFRDCRNVSQFFQK
Kinase aSWK440.AA APH 201-247 23 0.000356 15.12 Pfam 151-199 (248) Show / Hide 
Range on Protein: 201-247
Range on HMM: 151-199/248
Sequence Identity: 23% (12 aa)

HVEDAGA-LYDRLMALIVKMARHGVIHGDFNEFNLIML--EDERIV--MIDF
..... . |...| |.     . ...||||.  |...   .|.  |   ||.
RQWWLWQRLWAWLEAHWP---PPCWCHGDFHPGNVMWDPRPDGGRVTGVIDW
Kinase aSWK440.AA APH 97-184 13 0.000993 13.6 Pfam 1-66 (248) Show / Hide 
Range on Protein: 97-184
Range on HMM: 1-66/248
Sequence Identity: 13% (13 aa)

VGNQIGIGKESDVYVGGDPELN-DLCLKFHRLGRTSFRKIKEKRDYHKKRKSASWLYLSR---LAAAKEFAFLKALQERGF--PVPKAVDVCRH
 . .|. | ....|  ....   .. |..                           | ..    ....|...|..| ..|.  |||. .. |..
WWRPISGGWSNRTYYRTTDD-RPRYVLRR---------------------------YPPPWWAEELHREHRWLRHLAAHGIPVPVPRVLWGCTD