Gene C04A11.3 (Nematode worm)

C04A11.3

Species: Nematode worm
Alias: aSWK310, CE07905, C04A11.3
External Links: Wormbase Link ,
Annotation: WormBase Physical Map location: X: 13646320-13651138, WormBase Genetic Map location: X:13.75,

Classification

Group: STE
Family: STE20
Subfamily: SLK

Sequence

Name Sequence Type Origin Length Description Download
C04A11.3.kin_dom Protein Kinase Domain Sugen global kinase HMM prediction 261 Kinase domain by global Sugen HMM Fasta, JSON
C04A11.3.AA Protein Genbank 1228 None Fasta, JSON

Protein domain

Protein domains of C04A11.3.AA. The domains are annotated by HMM profiles from Pfam and SMART, as well as in-house data which includes HMMs of each individual kinase group, family and subfamily. Here is domain list in details, including sequence identity, significance and alignment. In particular, you can find can find the best hit kinase group/family/subfamily, which is helpful to understand the relationship between kinases.Kinase domain and best hit kinase group/family/subfamily are highlighted in red and blue. Visualized by pviz.

Usage: Zoom in selected region by dragging mouse and zoom out by double-clicking.

Show/hide domain list
Domain Protein name Domain Name Range Identity (%) Significance Score Profile Source Profile Range (length) Alignment
Kinase C04A11.3.AA SLK 34-294 67 1.3e-178 599.66 In-house 1-259 (259) Show / Hide 
Range on Protein: 34-294
Range on HMM: 1-259/259
Sequence Identity: 67% (176 aa)

WNIIGELGDGAFGKVEKAVSRTDPKLFAASKSIEIQEGEELEDFLVEIEILSECKGHPVMLGLYSTYFFENKLTMLLEFCGGGAVDNIIVELGHVLKEDQ
|.|||||||||||||.||... ..|.|||.|.|||...|||||..|||.|||||| ||....||..|...|||.|..|||.|||||||.|||.|.|.|||
WEIIGELGDGAFGKVYKAQHK-EQKVFAAAKMIEIKDEEELEDYMVEIDILSECK-HPNIVKLYEAYYYDNKLWMMIEFCDGGAVDNIMVELEHPLTEDQ

IRYIGYYVCDALKWLHSQNVIHRDLKAGNILLTQDGQVRLADFGVSAKLKSEREKRDTFIGTPYWMAPEVMACETFKDQPYDCISDIWSFGITLIEMAQG
|.|.....|.||.||||..||||||||||||.|.||.|||||||||||.|....||||||||||||||||..||||||||||...||||.|||||||||.
IQYVCKHMCEALNWLHSNKVIHRDLKAGNILMTMDGDVRLADFGVSAKNKHTMQKRDTFIGTPYWMAPEVVMCETFKDQPYDYKADIWSLGITLIEMAQM

EPPHSDVSVMRVIIKVQKSEPPTLLQPSHWTRSFSDILTRCLVKDPRNRPPAAEIFKHQWF
||||.....|||..|.||||||||.|||||...|.|.|..||||||.||...|....|||.
EPPHHEMNPMRVLLKIQKSEPPTLEQPSHWSKEFKDFLKKCLVKDPQNRWTTAQLMQHQWV
Kinase C04A11.3.AA STE20 34-294 39 1.6e-127 429.94 In-house 1-288 (288) Show / Hide 
Range on Protein: 34-294
Range on HMM: 1-288/288
Sequence Identity: 39% (115 aa)

WNIIGELGDGAFGKVEKAVSRTDPKLF----AASKSIEIQEG----EELEDFLVEIEILSECKGHPVMLGLYSTYFFE----NKLTMLLEFCGGGAVDNI
.... ..| |..||| ||   .. .      .| | ... .     .|.|| . || |...|| ||     | .|. .    ..| .. |.|||| .  |
YELLEKIGQGSYGKVYKA-YHKPTGEYCNQRVAIKKMNLEKCDNEQDEWEDIQKEISIMKQCK-HPNIVKYYGSYLKDDTCDDELWIVMEYCGGGSLTDI

IV---ELGH-----VLKEDQIRYIGYYVCDALKWLHSQNVIHRDLKAGNILLTQDGQVRLADFGVSAKLKS----ERE-KRDTFIGTPYWMAPEVMACET
.    ..|      ...|.|| || . |. .|. |||...||||.||.|||||.||.| ||||||.|.| .     .  ||.||.||||||||||..|..
MKHCMKCGKNHKGHPMNEEQIAYICREVLQGLDYLHSNHIIHRDIKADNILLTEDGEVKLADFGVCAQLTKHGRDTMQFKRNTFVGTPYWMAPEVIQCME

FKDQPYDCISDIWSFGITLIEMAQGEPPHSDVSVMRVIIKVQ--KSEPPTLLQ--PSHWTRSFSDILTRCLVKDPRNRPPAAEIFKHQWF
..|..||. .||||.|||.|||| ||||..|.. ||.. ..   . .|||| .  |..|. .| | . .||.||| .|| | .  ||...
GPDKGYDYKCDIWSLGITAIEMAEGEPPYFDMHPMRAMFMIPKNQNPPPTLKDDKPHKWSPEFHDFVDKCLQKDPEKRPTASQLLKHPFI
Kinase C04A11.3.AA STE 34-294 29 4.7e-101 342.03 In-house 1-359 (359) Show / Hide 
Range on Protein: 34-294
Range on HMM: 1-359/359
Sequence Identity: 29% (107 aa)

WNIIGELGDGAFGKVEKAVSRTDP--------------KLFAASKSIEIQEG-----------------EELEDFLVEIEILSECKG-HPVMLGLYSTYF
| .|...| ||||.| ||. . ..              . . | | .....                  ||....| ||.|...|.  ||     | .||
WEGIEKIGKGAFGTVYKAMNHKNCNIHKTGEVENNGETGEIMAIKQMNLENCNNKDENQENQELENKNHEEMQQILKEIKIMKKCNHMHPNIVKYYGCYF

FE-------NKLTMLLEFCGGGAVDNIIVELGHVLK-------------EDQIRYIGYYVCDA-LKWLHSQNVIHRDLKAGNILLTQDGQVRLADFGVSA
 |       ..| . .|...|| .| || . . ..|             |.||.|| . .. . |. |||...||||.|..||||     | |.||||..
KEGHNHKNDDELWICMEYMDGGSLDDIIKHKYGCGKPLNHNRQHQHRFPESQIAYICRQILKGLLYYLHSHHIIHRDIKPANILL-----VKLCDFGVCG

KLKSE----------------REKRDTFIGTPYWMAPEVMACETFK-DQPYDCISDIWSFGITLIEMAQGEPPHSDVSVMRVIIKVQKS-----------
.| ..                 .||.||.||| ||||||. ... . |..||. .||||.|.|.|||| |.||..| . ||..   ...           
QLTDSMANIQSNNIIDCIETMQQKRNTFVGTP-WMAPEVIQQNGQGRDKGYDTKCDIWSLGCTIIEMATGKPPWHDMHPMRAMFMIPFNYHMQQQFEQLC

----EPPTLLQ-----------------PSHWTRSFSDILTRCLVKDPRNRPPAAEIFK--HQWF
    .||.| .                 |..|. .| | . .||.|||..|| | .  |  | ..
IVNGPPPPLPDHLSQNEMISYGGSGTTYPHKWSPEFKDFINKCLQKDPNKRPTASQLLKSEHPFI
Kinase C04A11.3.AA S_TKc 34-294 31 5.6e-85 289.55 SMART 1-231 (231) Show / Hide 
Range on Protein: 34-294
Range on HMM: 1-231/231
Sequence Identity: 31% (87 aa)

WNIIGELGDGAFGKVEKAVSRTDPKLFAASKSIEIQEGEELEDFLVEIEILSECKGHPVMLGLYSTYFFENKLTMLLEFCGG--GAVDNIIVELGHV---
. |. ..| |||||| |.. .   .   | | |        |... ||.||..  .||    || ..   ..| | .|.|.|  | .  .|.. |.    
YEILRKIGKGAFGKVYKCRHKK-TGRIVAIKIIK-------EHIRREIQILKK--HHPNIVKLYDVFQD-DHLYMVMEYCDGDLGDLFDYIKKRGRHGLR

--LKEDQIRYIGYYVCDALKWLHSQNVIHRDLKAGNILLTQDGQVRLADFGVSAKLKSEREKRDTFIGTPYWMAPEVMACETFKDQPYDC-ISDIWSFGI
  . | ..|.. | .|.||. .||...||||||  ||||..  .. ..|||....|       .||.|||..|||||.        .|..  .|.||.|.
FPFPE-HARFYMYQICCALEYCHSHGIIHRDLKPENILLDE--HIKICDFGLARQL-------TTFCGTPWYMAPEVL--------GYGKCKCDWWSCGC

TLIEMAQGEPPHSDVSVMRVIIKVQKSEPPTLLQPSHWTRSFSDILTRCLVKDPRNRPPAAEIFK-------HQWF
.|.||. |.|| .    | ...|. .            .... |.. .||.|||..|| | |...       |.||
ILYEMLCGYPPFP---QMQMMFKKIG------------SPEAKDFIRKCLQKDPEKRPTA-EALQDEWDIKCHPWF
Kinase C04A11.3.AA YSK 34-294 38 2.1e-81 244.79 In-house 1-257 (257) Show / Hide 
Range on Protein: 34-294
Range on HMM: 1-257/257
Sequence Identity: 38% (102 aa)

WNIIGELGDGAFGKVEKAVSRTDPKLFAASKSIEIQEGE-ELEDFLVEIEILSECKGHPVMLGLYSTYFFENKLTMLLEFCGGGAVDNIIVE--LGHVLK
. .    | | || | |.. .   .  |  | |.  . | | ||   || .||.|.        | .|    ||    |.|||| .   .    .|  . 
FTKQECIGRGSFGEVYKGIDNRTQRVVAI-KIIDLEHAEDEIEDIQQEIQFLSQCDSP-YITKYYGSYLKDTKLWIIMEYCGGGSCLDLMKPKYVGQ-FD

EDQIRYIGYYVCDALKWLHSQNVIHRDLKAGNILLTQDGQVRLADFGVSAKLKSEREKRDTFIGTPYWMAPEVMACETFKDQPYDCISDIWSFGITLIEM
| .|  |   .  .|. |||...|||| || |.||. .|.| |.||||....     ||.||.||||||||||  .|      ||   |||| ||| .||
EKYIAIILREILKGLDYLHSERKIHRDIKAANVLLSEHGDVKLCDFGVAGQITDTQIKRNTFVGTPYWMAPEVICQEV---SYYDFKADIWSLGITAYEM

AQGEPPHSDVSVMRVIIKVQKSEPPTLLQPSHWTRSFSDILTRCLVKDPRNRPPAAEIFKHQWF
| ||||..|.  |||   . |..||. |. .... .| .    ||.|||..|| | |  ||.  
AKGEPPYCDYHPMRVMFLIPKNNPPK-LEGRSYSKMFKEFVECCLNKDPEQRPSAKELLKHKFI
Kinase C04A11.3.AA MST 34-294 40 7.1e-79 250.32 In-house 1-254 (254) Show / Hide 
Range on Protein: 34-294
Range on HMM: 1-254/254
Sequence Identity: 40% (106 aa)

WNIIGELGDGAFGKVEKAVSRTDPKLFAASKSIEIQEGEELEDFLVEIEILSECKGHPVMLGLYSTYF--FENKLTMLLEFCGGGAVDNIIVELGHVLKE
  |.. || |..|.| ||. . . |. |  | . .   | |.. . || |...||   .  ..|  ||   .| .    |.||.| |  |.   . .| |
FDIVEKLGQGSYGSVYKAIHKQTGKIVAI-KMVPV--NEDLQEIIKEISIMQQCKSKYIV-KYYGSYFDAKNNHCWIVMEYCGMGSVCDIMKITQRTLNE

DQIRYIGYYVCDALKWLHSQNVIHRDLKAGNILLTQDGQVRLADFGVSAKLKSEREKRDTFIGTPYWMAPEVMACETFKDQPYDCISDIWSFGITLIEMA
.||  | | .   |. ||.   ||||.||||||| ..|   |||||||. |     ||.|.|||||||||||        . |||  |||| ||| ||||
QQIACILYDTLQGLQYLHDNKKIHRDIKAGNILLNHEGECKLADFGVSGQLTDTMAKRNTVIGTPYWMAPEVI-----QEIKYDCKADIWSLGITAIEMA

QGEPPHSDVSVMRVIIKVQKSEPPTLLQPSHWTRSFSDILTRCLVKDPRNRPPAAEIFKHQWF
 |.|| ||.  ||.... ... |||.  |. |   |.| . .||.|.|  |. | .  .|  .
EGMPPYSDIHPMRAMFMIPQKPPPTFKDPEQWSQEFNDFVCKCLQKNPEQRWTAEQLLQHPFI
Kinase C04A11.3.AA KHS 34-294 38 1.1e-72 243.83 In-house 1-258 (258) Show / Hide 
Range on Protein: 34-294
Range on HMM: 1-258/258
Sequence Identity: 38% (100 aa)

WNIIGELGDGAFGKVEKAVSRTDPKLFAASKSIEIQEGEELEDFLVEIEILSECKGHPVMLGLYSTYFFENKLTMLLEFCGGGAVDNIIVELGHVLKEDQ
....  .| | .| | ||      .| || | | .. |....    || .. .|. || ... .  |. ..|| . .|.||||.. .|    |. |.| |
YELLQRVGSGTYGDVYKARDIQSDEL-AAVKVIKMEPGDDFAVIQQEIMMMKDCR-HPNIVAYFGSYLRRDKLWICMEYCGGGSLQDIYHVTGP-LSELQ

IRYIGYYVCDALKWLHSQNVIHRDLKAGNILLTQDGQVRLADFGVSAKLKSEREKRDTFIGTPYWMAPEVMACETFKDQPYDCISDIWSFGITLIEMAQG
| |.   .  .|..|||.  .|||.|  |||||..|.|.||||||||..     ||  |||||||||||| | |  .   |. . |||. ||| ||.|  
IAYVCRETLQGLHYLHSMGKMHRDIKGANILLTDQGDVKLADFGVSAQITATIAKRKSFIGTPYWMAPEVAAVE--RKGGYNQLCDIWAVGITAIELAEL

EPPHSDVSVMRVIIKVQKS--EPPTLLQPSHWTRSFSDILTRCLVKDPRNRPPAAEIFKHQWF
 ||  |.  ||... . ||  .||.| . ..|. .| . .  .|.|.|. || |  . .|...
QPPMFDLHPMRALFLMTKSNFQPPKLKDKHKWSQTFHHFVKMALTKNPKKRPTAEKLLQHPFV
Kinase C04A11.3.AA MSN 34-294 38 9.6e-69 226.05 In-house 1-265 (265) Show / Hide 
Range on Protein: 34-294
Range on HMM: 1-265/265
Sequence Identity: 38% (104 aa)

WNIIGELGDGAFGKVEKAVSRTDPKLFAASKSIEIQEGEELEDFLVEIEILSECKGHPVMLGLYSTYF------FENKLTMLLEFCGGGAVDNIIVEL-G
....  .| |..|.| | .     .| || | ....| || |.   || .|     |  .   |  ..       ...| | .|||| |.| ... .  |
FELVEVVGNGTYGQVYKGRHVKTGQL-AAIKVMDVREDEE-EEIKQEINMLKKYSHHRNIATYYGAFIKKSPPGHDHQLWMVMEFCGAGSVTDLVKMTKG

HVLKEDQIRYIGYYVCDALKWLHSQNVIHRDLKAGNILLTQDGQVRLADFGVSAKLKSEREKRDTFIGTPYWMAPEVMACETFKDQPYDCISDIWSFGIT
. |||| | ||   .   | .||.. |||||.|  |.|||.. .|.| ||||||.|     .| |||||||||||||.||.   |  ||  ||.|| |||
QSLKEDWIAYICREILRGLAHLHQHKVIHRDIKGQNVLLTHNAEVKLVDFGVSAQLDRTVGRRNTFIGTPYWMAPEVIACDENPDATYDYRSDLWSVGIT

LIEMAQGEPPHSDVSVMRVIIKVQKSEPPTLLQPSHWTRSFSDILTRCLVKDPRNRPPAAEIFKHQWF
 |||| |.||  |.  || .. . .  ||.|   . |.. | . . .||.|.   || .....|| . 
AIEMAEGQPPLCDMHPMRALFLIPRNPPPKLK-SKKWSKKFHNFMEKCLIKNYHQRPYTEQMLKHPFI
Kinase C04A11.3.AA NinaC 34-294 38 1.8e-68 233.75 In-house 1-267 (267) Show / Hide 
Range on Protein: 34-294
Range on HMM: 1-267/267
Sequence Identity: 38% (106 aa)

WNIIGELGDGAFGKVEKAVSRTDPKLFAASKSIEIQEGEELEDFLVEIE----ILSECKGHPVMLGLYSTYFFENKLT-----MLLEFCGGGAVDNIIVE
| |. . | | .||| |.  . . .. |    . ||  .  .|  .|||    || .   || .   |  |.   |       . .|.| || | ...  
WEIYETIGKGTYGKVFKVKNKDNGQIAA----VKIQ--HYIHDHDEEIEAEYNILRDYCDHPNVVRFYGMYYKKDKCNGDQLWFVMEYCNGGSVTDMVKG

L---GHVLKEDQIRYIGYYVCDALKWLHSQNVIHRDLKAGNILLTQDGQVRLADFGVSAKLKSEREKRDTFIGTPYWMAPEVMACETFKDQPYDCISDIW
|   |  ..|. | || .  | .|  ||.  ||||| |  |||||..| |.| |||||| | | | .| | .|||.|||||| ||.   |  ||   |.|
LLKCGRRMREEHIAYILHEACMGLQHLHCNHVIHRDVKGNNILLTTEGGVKLCDFGVSAQLDSTRHRRNTCVGTPCWMAPEVIACMQQYDPDYDARCDVW

SFGITLIEMAQGEPPHSDVSVMRVIIKVQKSEPPTLLQPSHWTRSFSDILTRCLVKDPRNRPPAAEIFKHQWF
| ||| ||.. |.||  |   || . |.    ||||..|  |   | |   .|| ||  .||   .. .|   
SLGITAIELGDGDPPFADMHPMRAMFKIPRNPPPTLMHPENWCQEFNDFISQCLEKDYEKRPMMVHMLEHPFI
Kinase C04A11.3.AA PAKL 36-294 40 5e-64 219.03 In-house 2-256 (256) Show / Hide 
Range on Protein: 36-294
Range on HMM: 2-256/256
Sequence Identity: 40% (105 aa)

IIGE-LGDGAFGKVEKAVSRTDPKLFAASKSIEIQEGEELEDFLVEIEILSECKGHPVMLGLYSTYFFE-NKLTMLLEFCGGGAVDNIIVELGHVLKEDQ
.. | ||.|..| | ||. . |     | |.||| |  | .|   ||.||  ||  |  .  .     . |..  |...|  | .  ..   .  |.| |
EFQEKLGQGSYGSVYKAIHK-DTNFPLAIKVIEIKESNEIKDIEKEIQILKKCKC-PNIVSYFGSIQQKLNHYWILMDYCSLGSINDMMESCCKTLNEKQ

IRYIGYYVCDALKWLHSQNVIHRDLKAGNILLTQDGQVRLADFGVSAKLKSERE-KRDTFIGTPYWMAPEVMACETFKDQPYDCISDIWSFGITLIEMAQ
|  |   .   |  |||.|.|||| || ||||. |.|| .|||||| .| .|        ||||||||||..     . |.|.   |||| |||.|||| 
ISVILQQTLKGLHYLHSKNIIHRDIKAANILLNEDCQVKIADFGVSQQLQDEYDGQANQMIGTPYWMAPEII-----NKQNYNNKCDIWSLGITAIEMAD

GEPPHSDVSVMRVIIKVQKSEPPTLLQPSHWTRSFSDILTRCLVKDPRNRPPAAEIFKHQWF
|.|||.|.  ||    .    |||.  | ||   | | | .|.||||  |. . .   |   
GFPPHYDMPPMRAMYMIPNWPPPTFSNPKHWSPCFNDFLAQCCVKDPEKRWSPIDLLCHPFI
Kinase C04A11.3.AA Pkinase 34-294 26 2.7e-63 221.39 Pfam 1-293 (293) Show / Hide 
Range on Protein: 34-294
Range on HMM: 1-293/293
Sequence Identity: 26% (81 aa)

WNIIGELGDGAFGKVEKAVSRTDPKLFAASKSIEIQEGEELED--FLV--EIEILSECKGHPVMLGLYSTYFFENKLTMLLEFCGGG----AVDNIIV-E
. |.. .| |.||.| |.. . ..|..|  | |. .. .. .|   .   ||.|. .. .||  . || ..  .... | .|.|.||        .|  .
YHIGRKIGSGSFGCVYKCHHKGTGKIVAV-KIIKKRHEKSWKDQTHRRLSEIQIMKRL-NHPNIVRLYDWFEDKDHIYMVMEYCEGGLYVMDLFDYISTW

LGHVL--KEDQIRYIGYYVCDALKWLHSQNVIHRDLKAGNILLTQDGQV----RLADFGVSAKL-KSEREKRDTFIGTPYWMAPEVMACETFKDQPYDCI
 . ..   |.... . | .. .|. .||...||||||  |||. ..|..    ...|||.....     .  .|| |||..|||||      ..|.|.  
RHGCFYFSEWECKFYMYQILRGLEYCHSMGIIHRDLKPENILIDNNGHIDACVKICDFGLAKQFDY-NNS-MTTFCGTPWYMAPEVIR----GGQYYGPK

SDIWSFGITLIEMAQGEPPHSDV----SVMRVIIKVQKSEPPTLLQPSHWT---------------------RSFSDILTRCLVKDPRNRPPAAEIFKHQ
.|.||.|..|.||. |.|| ..     . .. . ....  .| |  .. |.                     ... |....|| |||  || |..|..| 
VDMWSCGCILYEMLCGRPPFPGHCWHDN-HDQMQMICRIMGPPLHFDWPWWCSISYFFFRHWHFHWTFHNWSEECKDFIKWCLCKDPKKRPTAEQILQHP

WF
||
WF
Kinase C04A11.3.AA PAKA 34-294 33 2.8e-56 193.3 In-house 1-260 (260) Show / Hide 
Range on Protein: 34-294
Range on HMM: 1-260/260
Sequence Identity: 33% (88 aa)

WNIIGELGDGAFGKVEKAVSRTDPKLF-AASKSIEIQEGEELEDFLVEIEILSECKGHPVMLGLYSTYFFENKLTMLLEFCGGGAVDNIIVELGH----V
 . . ..| || |.| .| ..  ..    | | .....    |  . || .. ||| |.     ...| .. .| . .|. .||    .| .       .
YKFMEKIGQGASGEVYVATNIKTNQEENVAIKQMNMKNQPKKELIINEILVMKECK-HKNIVNYIDSYLVDDELWVVMEYMEGGCLTDVITQCCNIQCNY

LKEDQIRYIGYYVCDALKWLHSQNVIHRDLKAGNILLTQDGQVRLADFGVSAKLKSEREKRDTFIGTPYWMAPEVMACETFKDQPYDCISDIWSFGITLI
..|.|| |.   .. .|. .||...||||.|  |||| .||.| ..|||  | |  |..||.|  ||||||||||      . . ||   |||| || .|
MDEGQIAYVCRECLQGLEFIHSKHRIHRDIKSDNILLGMDGSVKITDFGFCAQLTQEQQKRNTMVGTPYWMAPEVI-----RRKQYDEKVDIWSLGIMAI

EMAQGEPPHSDVSVMRVIIKVQKSEPPTLLQPSHWTRSFSDILTRCLVKDPRNRPPAAEIFKHQWF
||. ||||. .    | .  . .   | ...|  |. .| | | .|| .|...|. | |  .|  .
EMIEGEPPYLNEPPLRAMYLIATNGKPDIKDPDKWSQEFCDFLDKCLCVDVDRRASAQELLHHPFL
Kinase C04A11.3.AA Pkinase_Tyr 108-288 24 4.1e-23 78.89 Pfam 84-266 (270) Show / Hide 
Range on Protein: 108-288
Range on HMM: 84-266/270
Sequence Identity: 24% (47 aa)

MLLEFCGGGAVDNIIVEL---GHVLKEDQIRYIGYYVCDALKWLHSQNVIHRDLKAGNILLTQDGQVRLADFGVSAKL--KSER-EKRDTFIGTPYWMAP
. .|.. .|  ..   .    .. |.  ..  . . ..... .|.|.| ||||| | |.|.| ...|. .||| .  .  ...   ||.       ||||
IVMEYMPHGDLLDYLRKHREDKQPLTMKDLLQMCWQIAKGMEYLESKNCIHRDLAARNCLVTENNVVKICDFGLARDIYNDDYYYRKRGGGKLPIKWMAP

E-VMACETFKDQPYDCISDIWSFGITLIEMAQ-GEPP-HSDVSVMRVIIKV-QKSEPPTLLQPSHWTRSFSDILTRCLVKDPRNRPPAAEI
|  . ..      .   ||.||||... |.   || |   ..|  .|. .. .. .   . .| . .    |....|  .|| .||  .||
ECINYGK------FTTKSDVWSFGVLMWEIFTYGEQPTYPGMSNEEVYEYIYEDGYR--MPCPENCPDEIYDLMKQCWHYDPEDRPTFSEI
Kinase C04A11.3.AA TyrKc 34-294 24 3e-19 71.18 SMART 1-280 (280) Show / Hide 
Range on Protein: 34-294
Range on HMM: 1-280/280
Sequence Identity: 24% (72 aa)

WNIIGELGDGAFGKVEKAVSRTDPKLFAASKSIEIQEGEELEDFLVEIEILSEC-KGHPVMLGLYSTYFFE-------NKLTMLLEFCGGGAVDNIIVEL
   . .|| ||||.| |.. .    .  | |..       .|||. |..|...  . ||  . ||     .         | ...|.. .|. .. . . 
ITLGKKLGEGAFGEVYKGTWK----IQVAVKMLKEDA---REDFMREARIMCKLGGHHPNIVRLYGVCTQQGRNFMYIEPLMIVMEYMPHGDLKDYLRKH

GHVLKEDQIRYIGYYVCDALKWLHSQNVIHRDLKAGNILLTQDGQVRLADFGVSAKLKSE-------REKRDTF-IGTP-----YWMAPEVMACETFKDQ
.. |. ..  .. . ...    |||.|.||||| | |.|.. ...|. .||| | .....         .| .   |.       |||||..     .. 
RPKLCMKDLLSFCWQIACGMEYLHSKNCIHRDLAARNCLVGENHTVKISDFGLSRDIYDDDQQGESKDYYRKKEHKGGKTMLPIRWMAPECI-----NYG

PYDCISDIWSFGITLIEMA-QGEPPHSD-----VSVMRVIIKVQKSEPPTLLQPSH--------WTRSFSDILTRCLVKDPRNRPPAAEIFKHQWF
 .   ||.||||... |.   |..|...     .|  .|| .|.. .   . || .         .    .| ..|   || .||  .||  |. |
KFTTKSDVWSFGVCMWEIFTYGQQPYPGMIQQMMSNQEVIEYVKQGY--RMPQPPNDYPMSFVCCPDEMYQIMKQCWHEDPEDRPTFSEI--HECF
Kinase C04A11.3.AA Pkinase_Tyr 34-91 31 0.097356 6.51 Pfam 1-64 (270) Show / Hide 
Range on Protein: 34-91
Range on HMM: 1-64/270
Sequence Identity: 31% (20 aa)

WNIIGELGDGAFGKVEKAVSR---TDPKLFAASKSI-EIQEGEE--LEDFLVEIEILSECKGHP
  .. .|| ||||.| |.. .    ..|.  | |.. |    |.  .|||. |..|...   ||
ITFGKKLGEGAFGEVYKGTWKGDPDNTKIPVAVKMLKEGAMHEQNCREDFMREAKIMKQLGHHP
PKK C04A11.3.AA PKK 857-995 38 1.3e-44 159.3 Pfam 1-144 (144) Show / Hide 
Range on Protein: 857-995
Range on HMM: 1-144/144
Sequence Identity: 38% (55 aa)

GIKLVEEQA-RKFTSEQTNLTRTSELEMDAMERRQRKEIEDTEGAQEHELRNAQKRLRIEQEKDMRAFKERLKQEMK--IFKQELTMLS--KVQRKDALK
 ..|. ||  ..|  ........ | ||..|||.|...||..|  |. |.|...||.| ||||.|..|||.||.|.|   .||| ...   . ||||..|
KHQLQKEQMKDQFFQQRHQMLKRHEKEMEQMERQQKQQIEKMEQRQTQERRRLPKRIRAEQEKRMKMFKESLKIEKKNMEPKQEVEKMPQFREQRKDRMK

QRKEQIEIEHQLKEKDFLMQLQQNAEAMLQRMAEKHKERMASIE
|..|..| .|| .|..|. |...| | |.|.| ..|..... .|
QEMEEMEQKHQEQEQEFVAQCEENHEEMMQQMQNEHRHMLMEHE
PKK C04A11.3.AA PKK 1024-1166 35 4.2e-46 164.29 Pfam 1-144 (144) Show / Hide 
Range on Protein: 1024-1166
Range on HMM: 1-144/144
Sequence Identity: 35% (51 aa)

KFVLHRKLFKDEYYLLRTQMLARHQREMAQIEKIHQEEEDDLIRALTLDRKKLPKMLRSETKTRSVMFKESLRISAVNMSNAEMQERIRRFDEQEALRMR
|. |... .||.... |.|||.||..|| |.|. .. ..... .  |..|..|||..|.|...| .||||||.|.. ||......|....|.||.  ||.
KHQLQKEQMKDQFFQQRHQMLKRHEKEMEQMERQQKQQIEKMEQRQTQERRRLPKRIRAEQEKRMKMFKESLKIEKKNMEPKQEVEKMPQFREQRKDRMK

AALEDHDLKSQKKLQILKERHQEAIIE-LDEMQNEKRKQLLEKE
.  | ...| |...| ......|.. | ...||||.|..|.|.|
QEMEEMEQKHQEQEQEFVAQCEENHEEMMQQMQNEHRHMLMEHE