Gene cmk-1 (Nematode worm)

cmk-1

Species: Nematode worm
Alias: CE25046, K07A9.2, cmk-1, aSWK031
External Links: Wormbase Link ,
Annotation: WormBase Physical Map location: IV: 1824491-1834055, WormBase Genetic Map location: n/a,

Classification

Group: CAMK
Family: CAMK1

Sequence

Name Sequence Type Origin Length Description Download
cmk-1.kin_dom Protein Kinase Domain Sugen global kinase HMM prediction 211 Kinase domain by global Sugen HMM Fasta, JSON
cmk-1.AA Protein Genbank 348 None Fasta, JSON

Protein domain

Protein domains of cmk-1.AA. The domains are annotated by HMM profiles from Pfam and SMART, as well as in-house data which includes HMMs of each individual kinase group, family and subfamily. Here is domain list in details, including sequence identity, significance and alignment. In particular, you can find can find the best hit kinase group/family/subfamily, which is helpful to understand the relationship between kinases.Kinase domain and best hit kinase group/family/subfamily are highlighted in red and blue. Visualized by pviz.

Usage: Zoom in selected region by dragging mouse and zoom out by double-clicking.

Show/hide domain list
Domain Protein name Domain Name Range Identity (%) Significance Score Profile Source Profile Range (length) Alignment
Kinase cmk-1.AA CAMK1 22-278 58 2.2e-212 623.8 In-house 1-276 (276) Show / Hide 
Range on Protein: 22-278
Range on HMM: 1-276/276
Sequence Identity: 58% (161 aa)

YDFRDVLGTGAFSKVFLAESKSD--AGQMYAVKCID-KKALKGKE----ESLENEIKVLRK---LRHNNIVQLFDTYDEKQFVYLVMELVTGGELFDRIV
| |....|.||||.|.|.. |.    |. ||.|||| ||..|.|.    |.||||| ...|   . | ||..... |... ..|||||||||||||||||
YEFGKEIGRGAFSEVYLCTHKETQTNGKQYAIKCIDKKKFMKKKDMQKQEALENEIEIMKKVSKIDHPNIIKFYEWYESDNHFYLVMELVTGGELFDRIV

AKGSYTEQDASNLIRQVLEAVGFMHDNGVVHRDLKPENLLYYNQDEDSKIM--ISDFGLSKTEDSG--VMATACGTPGYVAPEVLQQ---KPYGKAVDVW
 ||.|||.||.....|.|.||..||..|.|||||||||||||..||||||.  |.|||||| .|..  .| |||||||||||||| .   |||.||.|.|
EKGNYTEKDARHIMKQILSAVEYMHSKGIVHRDLKPENLLYYDKDEDSKIKRSIADFGLSKIFDHDENLMKTACGTPGYVAPEVLECKKDKPYDKACDMW

SIGVIAYILLCGYPPFYDES-DANLFAQIIKGEYEFDAPYWDQISDS-AKDFITHLMCCDPEARFTCQDALSHPWI
||||| |||||||||||||. |..||..|.|.||||. |.|| |||. |||||.|....||. |.||...| ||||
SIGVITYILLCGYPPFYDENVDNELFEKIKKCEYEFPSPWWDNISDQEAKDFIKHMLEVDPKKRYTCEQCLNHPWI
Kinase cmk-1.AA CAMK 27-278 29 1.6e-138 449.32 In-house 1-425 (425) Show / Hide 
Range on Protein: 27-278
Range on HMM: 1-425/425
Sequence Identity: 29% (124 aa)

VLGTGAFSKVFLAESKSDAG-----------QMYAVKCIDKKALKG---------------------------KEESLENEIKVLRK-------LRHNNI
.||.|.|.||.|.. |.. |           | .|.| |||| ||.                           .......||....|       |.| ||
TLGRGSFGKVKLCIHKNTTGKERVHHIYTNGQKVAIKIIDKKKLKDKQNQDYSNCYKIDKSKCKHRYCWRRPKDRKNVRREIEIMKKLQGIGNKLDHPNI

VQLFDTYDE-------------------KQFVYLVM---ELVTGGEL----FDRIVAKGS---------------YTEQDASNLIRQVLEAVGFMHDNGV
..|...|.                    ....|.||   |...||||    ||.||..|.               .||..|. ..||...|| ..|....
IKLYEVYEDPHYFKNTNDYETSKQVFTKDKHMYMVMEIMEYCSGGELFDDLFDYIVEHGCYGEEFDQFDIVERGRFTEREARRYFRQICSAVHYCHSHNI

VHRDLKPENLLYYNQDEDS--------------KIMISDFGLSKTEDSGV-------------------------MATACGTPGYVA-PEVLQQ------
|||||||||.|. . ..||              .| |.|||...  |.|                          | | ||||.|.| ||||..      
VHRDLKPENILLDDNNDDSDPVEHDEIFDWNNNNIKIIDFGFANKFDPGENNFMCSDYKGGEMHNQWTTPTEGQKMKTFCGTPEYMAAPEVLNGKGHCNM

--------KPYGKAVDVWSIGVIAYILLCGYPPFYDE-------------SDANLFAQIIKGEYEFDAPY------------WDQISDS--------AKD
        ..||...|.||.||| ||.||||||||..             .| .|| .|.||.|.|. ||            || |||.        .||
QNATDEEKPYYGPKCDMWSCGVILYIMLCGYPPFYGDCDNEICEDEWIGMNDYELFEKIMKGKYDFPPPYFSPISCNYGPEWWDDISDEFHHFVSQECKD

FITHLMCCDPEARFTCQDALSHPWI
.| .... ||| |.|....|.|||.
LIRKMLQVDPEKRMTIEQCLNHPWM
Kinase cmk-1.AA RAD53 22-278 41 7.50000000001e-133 398.27 In-house 1-305 (305) Show / Hide 
Range on Protein: 22-278
Range on HMM: 1-305/305
Sequence Identity: 41% (126 aa)

YDFRDVLGTGAFSKVFLAESKSDAGQMYAVKCIDKKALK-------GKEESLENEIKVLRKLRHNNIVQLFDTYDEK-QFVYLVMELVTGGELFDRIVAK
|... .||.|.|..| ||  |.. .| .|.| |||| .        .|.....||...|.|| | .|....| .|.. . .|.|.||.||||||..||. 
YYMSKELGSGNFGTVKLAYEKKT-CQKVAIKIIDKKKFFIRCMHTIKKMDQVMNEVEILKKLNHPCIIRIYDIFDTPQKYYYMVLELMTGGELFNKIVSN

GS----YTEQDASNLIRQVLEAVGFMHDNGVVHRDLKPENLLYYNQDEDS---------------KIMISDFGLSKTEDSG-VMATACGTPGYVAPEVLQ
.     ..| ..  . .| ..||   |||| .|||||||| |. .|||.                .| |.||||||. . | .| | |||| ||||||. 
KRCQMGFDEDTCKYYFYQMCDAVKYLHDNGICHRDLKPENILCNHQDEECPQVQLGPWDEDEISFLIKITDFGLSKFVGEGSFMKTMCGTPQYVAPEVIT

QK---------------PYGKAVDVWSIGVIAYILLCGYPPFYDESD-----ANLFAQIIK-GEYEFDAPYWDQISDSAKDFITHLMCCDPEARFTCQDA
 |                |.|.||.||.|.| ||.||||||| |...      .|| ||.. | |.|. |||| ||..|||.|  . | |||.|.|. .|
SKGHNCYHENEERQVQVGYTKKVDCWSMGCILYICLCGYPPFSDDYTQEMHCMQLFEQIKNQGKYHFPHPYWDRISEEAKDLIKWMLCVDPEKRYTIDEA

LSHPWI
|.|||.
LNHPWM
Kinase cmk-1.AA CDPK 22-278 45 7.70000000001e-126 387.84 In-house 1-271 (271) Show / Hide 
Range on Protein: 22-278
Range on HMM: 1-271/271
Sequence Identity: 45% (123 aa)

YDFRDVLGTGAFSKVFLAESKSDAGQMY-AVKCIDKKALKGKE--ESLENEIKVLRKLRHNNIVQLFDTYDEKQFVYLVME--LVTGGELFDRIVAKGSY
|.. .|||.|.|. |...  |.  .|   |.| | |. .| ||  ... |||..|..| | ||.... .|  ....|.|||  ..|||||||.|..||..
YKIKKVLGKGHFGQVRKVKHKQKTNQERVAMKIIPKSRVKDKEQQQQFFNEIEILKQLDHPNIIKIYEFYQDEKNYYIVMETEYCTGGELFDYIIEKGHF

TEQDASNLIRQVLEAVGFMHDNGVVHRDLKPENLLYYNQDEDS----KIMISDFGLSKTEDS------GVMATACGTPGYVAPEVLQQKPYGKAVDVWSI
||..|.. .||.| ||  .|.|..|||||||||.|. . ..||     | . |.|.||  |.       .| . |||| |.||||||.| | . .|.||.
TEKEAAYIMRQILSAVNYCHSNNIVHRDLKPENILFDSKKDDSWVIYNIKVIDWGTSKKFDQNQKIEDKKMSQRCGTPYYIAPEVLQKK-YNEKCDIWSC

GVIAYILLCGYPPFYDESDANLFAQIIKGEYEFDAPYWDQISDSAKDFITHLMCCDPEARFTCQDALSHPWI
||| ||||||||||| ..|   .... ||.|.|. | || |||.||| |  . | ||. |...|.|| |||.
GVILYILLCGYPPFYGKNDQEIMEKVKKGKYSFEGPEWDHISDEAKDLIRKMLCYDPKKRMSAQQALQHPWF
Kinase cmk-1.AA DCAMKL 22-278 40 3.7e-120 375.66 In-house 1-279 (279) Show / Hide 
Range on Protein: 22-278
Range on HMM: 1-279/279
Sequence Identity: 40% (113 aa)

YDFRDVLGTGAFSKVFLAESKSDAGQMYAVKC-----------------IDKKALKGKEESLENEIKVLRKLRHNNIVQLFDTYDEKQFVYLVMELVTGG
|.   . | | |. |...  .... . || |                  |||...||||   .||.....|..| .|.|| . .| ..  |||||.|.||
YQIGRIIGDGNFAVVHECRHRETGDHKYAMKIRYQSTLQFSFPSKFFQQIDKRKCKGKEHMIDNEVSIMQKIKHPHIIQLYEHWDTETHYYLVMEYVQGG

ELFDRIVAKGSYTEQDASNLIRQVLEAVGFMHDNGVVHRDLKPENLLYYN-QDEDSKIMISDFGLSKTEDS--GVMATACGTPGYVAPEVLQQKPYGKAV
 ||| |.  . .|| ||. ..... .|  ..|. ..||||.|||||| .  .|    .   |||| .  .   |.. | |||| |||||.|. . ||  |
DLFDAITENTKFTERDAAIMMTCLCKALKYLHEMNIVHRDIKPENLLVCKHEDGEKSLKLCDFGLACHVNGDFGPLYTVCGTPTYVAPEILMETGYGCKV

DVWSIGVIAYILLCGYPPFYDE--SDANLFAQIIKGEYEFDAPYWDQISDSAKDFITHLMCCDPEARFTCQDALSHPWI
|.|..||| ||||||.|||  .  .   || ||. |..||..|||| ||||||| |.|..  |||.|.| .. ..|||.
DIWAAGVILYILLCGFPPFRSPDNDQEELFDQIMQGKFEFPMPYWDNISDSAKDLISHMLQVDPEKRYTAEQIMQHPWV
Kinase cmk-1.AA PSK 22-278 45 1.2e-113 364.59 In-house 1-258 (258) Show / Hide 
Range on Protein: 22-278
Range on HMM: 1-258/258
Sequence Identity: 45% (118 aa)

YDFRDVLGTGAFSKVFLAESKSDAGQMYAVKCIDKKALKGKEESLENEIKVLRKLRHNNIVQLFDTYDEKQFVYLVMELVTGGELFDRIVAKGSYTEQDA
|| . . |.| ||.|   | ..   | ||.| ...|   |. |  ||| ..|| .|| .|.||   .. .. ||.|||. ||||.||||||||..||.||
YDIKALIGKGSFSRVVRVEHRV-TRQPYAIKMVETKCREGR-EFCENELNILRRVRHPYIIQLMEVFETQDRVYMVMEMATGGEMFDRIVAKGRFTERDA

SNLIRQVLEAVGFMHDNGVVHRDLKPENLLYYNQDEDSKIMISDFGL---SKTEDSGVMATACGTPGYVAPEVLQQKPYGKAVDVWSIGVIAYILLCGYP
 .  . ||... ..|  .. ||||||||||||   ..||||| ||||    |. .  .| | |||| |.|||||  ||| ..|| | .|||||||. |  
TRVLQMVLDGMRYLHALRITHRDLKPENLLYYHPGNESKIMITDFGLAYQRKKSNDWMMKTTCGTPEYIAPEVLLRKPYTQSVDMWAVGVIAYILMSGIM

PFYDESDANLFAQIIKGEYEFDAPYWDQISDSAKDFITHLMCCDPEARFTCQDALSHPWI
|| |..   |. .|..| | .   .|  .|. |||||  |.  .. .| |   |. |||.
PFDDDCRTRLYRHILTGKYNYYGQPWPSVSHLAKDFIDKLLEINQGERMTASQAMKHPWV
Kinase cmk-1.AA Ciliate-E2a 22-278 38 8e-113 333.42 In-house 1-275 (275) Show / Hide 
Range on Protein: 22-278
Range on HMM: 1-275/275
Sequence Identity: 38% (106 aa)

YDFRDVLGTGAFSKVFLAESKSDAGQMYAVKCIDKKALKGK--EESLENEIKVLRKLRHNNIVQLFDTYDEKQFVYLVMELVTGGELFDRIVAKGSYTEQ
|.| ...|.|.| .|.||. | . |...|.| ..||.   |  .|...|||. .|.|.| || .|...|  ..  |||||.. ||||.|.|. .....| 
YKFIKKIGKGNFGSVYLAQHKQT-GKQFAMKKFIKKMYQQKKGKEYFMNEINIMRQLDHPNIIKLYEVYEDENNYYLVMEYCEGGELYDKIKQCKRFFEE

--DASNLIRQVL-EAVGFMHDNGVVHRDLKPENLLYY---NQD-EDSKIMISDFGLSKTE--DSG-VMATACGTPGYVA------PEVLQQKPYGKAVDV
  ... ...| | ...  || ....||||||||.|.     .. ..|.|.|.||||..    |.. .| . ||||||||      .|||..| |.. .|.
IQEICDIMQQLLWQGLHYMHQRNIMHRDLKPENILFKNCSKNSIQNSDIKIIDFGLATFIDKDEKKYMFQKCGTPGYVAPEVLNNKEVLKHKQYDTKCDM

WSIGVIAYILLCGYPPFYDESDANLFAQIIKGEYEFDAPY-WDQISDSAKDFITHLMCCDPEARFTCQDALSHPWI
||.||| ||||||.|||. .. .  . |. | .. |. |  | ..|...||..  .  .||. |.|.|.|| ||| 
WSCGVIFYILLCGKPPFKGKTYNEILQQNKKCKIDFNCPECWEKCSKECKDLMKKMLEKDPKKRITAQQALNHPWF
Kinase cmk-1.AA S_TKc 22-278 36 4.90000000001e-108 366.13 SMART 1-231 (231) Show / Hide 
Range on Protein: 22-278
Range on HMM: 1-231/231
Sequence Identity: 36% (99 aa)

YDFRDVLGTGAFSKVFLAESKSDAGQMYAVKCIDKKALKGKEESLENEIKVLRKLRHNNIVQLFDTYDEKQFVYLVMELVTG--GELFDRIVAKGS----
|.. ...| |||.||...  |.  |. .|.|.|.        |....||..|.| .| |||.|.|.... ...|.|||.. |  |.|||.|. .|.    
YEILRKIGKGAFGKVYKCRHKK-TGRIVAIKIIK--------EHIRREIQILKK-HHPNIVKLYDVFQD-DHLYMVMEYCDGDLGDLFDYIKKRGRHGLR

--YTEQDASNLIRQVLEAVGFMHDNGVVHRDLKPENLLYYNQDEDSKIMISDFGLSKTEDSGVMATACGTPGYVAPEVLQQKPYGK-AVDVWSIGVIAYI
  ..| .|  ...|...|. ..|..|..||||||||.|  .      |.|.||||..        | |||| |.|||||   .||| ..|.||.|.| |.
FPFPE-HARFYMYQICCALEYCHSHGIIHRDLKPENILLDE-----HIKICDFGLARQL-----TTFCGTPWYMAPEVL---GYGKCKCDWWSCGCILYE

LLCGYPPFYDESDANLFAQIIKGEYEFDAPYWDQISDSAKDFITHLMCCDPEARFTCQDALS-------HPWI
.|||||||.   . ..  ..|.             |..||||| .... ||| | |. .||        |||.
MLCGYPPFP---QMQMMFKKIG-------------SPEAKDFIRKCLQKDPEKRPTA-EALQDEWDIKCHPWF
Kinase cmk-1.AA CAMK-Unique 22-278 26 2.9e-103 341.75 In-house 1-363 (363) Show / Hide 
Range on Protein: 22-278
Range on HMM: 1-363/363
Sequence Identity: 26% (96 aa)

YDFRDVLGTGAFSKVFLAESKSDAGQMYAVKCIDK---KALKGKE----------------ESLENEIKVLRKLRHNNIVQLFDT----YDEKQ------
|..  ..|.|.|..|. .  ..  |  .|.| . |   .  |.|.                 .|..|. ..... |.||..|.|.    .  ..      
YKMHRIIGHGNFGHVYECMDRET-GKKWACKMVKKQTHGNKKQKQQRNFDLRYKITEKRRDMKLKREHQIWKMVDHPNIIKLYDWNNPIFCDRKYPLCDL

---------FVYLVMELVTGGELFDRIVA--------------------KGSYTE--QDASNLIRQVLEAVGFMHDNGVVHRDLKPENLLYYNQ-DE---
           |.|||...||.||| |..                    .|...|   |........|.|| .||....||||||.||.....  ..   
IIKTPRALPYMYIVMEYCQGGDLFDWIQKWDEFYFNFIIKFDFNILKRCQGHFSERCWDTCFIMQCLLSAVAYMHSQDIVHRDLKLENIMVCYSFKDNNH

---------DSKIMISDFGLSKTED-SGVMA---TACGTPGYVAP--------------EVLQQKPYGKAV----DVWSIGVIAYILLCGYPPFYDESDA
         ...| ..||||.. .. . . .   | |||| |.||              ||. . .|.  .    | ||.|||.|..|||.|||. |...
HRDFPYDWSNWHIKLCDFGLCCHYNHNKMCHMMQTMCGTPCYMAPEIVFCKNYQEMTRDEVINMQCYDQQCSPASDIWSLGVIMYYMLCGCPPFDCECED

--------NLFAQIIKGEY-EFDAPYWDQ---ISDSAKDFITHLMCCDPEARFTCQDALSHPWI
        ..|. | ||.| .|| ..|.    ||..||||.. .|  ||  | ..  .|.|.||
RDYENHDKEIFECICKGDYCNFDWKMWHGPDYISQEAKDFVKCCMTVDPDHRWSAKELLEHQWI
Kinase cmk-1.AA CAMKL 22-278 34 2.2e-100 321.07 In-house 1-297 (297) Show / Hide 
Range on Protein: 22-278
Range on HMM: 1-297/297
Sequence Identity: 34% (103 aa)

YDFRDVLGTGAFSKVFLAESKSDAGQMYAVKCIDKKALKGKEESLEN--------------EIKVLRKLR---HNNIVQLFDTYDEKQF------VYLVM
|.. ..||.|.|.|| ||. ..  |...|.| |||| .. .. .. |              ||. ...|.   | ||..|..... ...      .||||
YRIGKTLGKGSFGKVKLATHIRTTGEKVAIKIIDKKKIWNDPWMKKNKCGQKHESDMRIRREIQIMKMLNIGKHPNIIKLYEVIETPEHDIETKKIYLVM

ELVTGGE--LFDRIVAK----GSYTEQDASNLIRQVLEAVGFMHDNGVVHRDLKPENLLYYNQDEDSKIMISDFGLSKT-ED-----SGVMATACGTPGY
|.. |||  |||.||..    |. .| .|  . ||...|| ..|..|.||||.||||.|  ...   .| |.|||.|   ..        . | ||.| |
EYCSGGEMDLFDYIVKHGHRRGRMPEHEARRYFRQIVSAVNYCHSHGIVHRDIKPENILLDENGNN-NIKIIDFGFSNMYRPCIFGPGQKLKTFCGSPPY

VAPEVLQQ--KPYG-KAVDVWSIGVIAYILLCGYPPFYDESDA-------NLFAQIIKGEYEFDAPYWDQISDSAKDFITHLMCCDPEARFTCQDALSHP
 |||..|   |||  ..||.||.||| | ..||| || |....       .|. .|..| |..  | | ..| ...|.| ...  .|| |.|... ..||
MAPEIFQGNNKPYDGPKVDIWSCGVILYAMVCGYLPFDDDTYNKQGKDNIYLYWKIMCG-YYP--PIWYHVS-DCRDLIRKMLQVNPEKRPTIHQIMNHP

WI
| 
WM
Kinase cmk-1.AA Pkinase 22-278 34 3.5e-98 337.28 Pfam 1-293 (293) Show / Hide 
Range on Protein: 22-278
Range on HMM: 1-293/293
Sequence Identity: 34% (102 aa)

YDFRDVLGTGAFSKVFLAESKSDAGQMYAVKCIDKKALKGKE-ESLEN--EIKVLRKLRHNNIVQLFDTYDEKQFVYLVMELVTGG----ELFDRIV--A
| .  ..| |.|..|...  |.. |...|||.|.|.  | .. ... .  ||.....|.| |||.|.|.. .|. .|.|||.. ||    .|||.|   .
YHIGRKIGSGSFGCVYKCHHKGT-GKIVAVKIIKKRHEKSWKDQTHRRLSEIQIMKRLNHPNIVRLYDWFEDKDHIYMVMEYCEGGLYVMDLFDYISTWR

KGSY--TEQDASNLIRQVLEAVGFMHDNGVVHRDLKPENLLYY-NQDEDSKIMISDFGLSK---TEDSGVMATACGTPGYVAPEVLQ-QKPYGKAVDVWS
.|..  .|... . ..|.|... ..|..|..||||||||.|.  | . |... |.||||.|   .  .. | | ||||.|.||||.. ...||..||.||
HGCFYFSEWECKFYMYQILRGLEYCHSMGIIHRDLKPENILIDNNGHIDACVKICDFGLAKQFDY-NNS-MTTFCGTPWYMAPEVIRGGQYYGPKVDMWS

IGVIAYILLCGYPPFYDE------SDANLFAQIIKGEYEFDAPYWDQIS-----------------DSAKDFITHLMCCDPEARFTCQDALSHPWI
.|.| |..|||.|||...      ..  ....| .....|| |.|. ||                 ...||||. . | ||. | |....| |||.
CGCILYEMLCGRPPFPGHCWHDNHDQMQMICRIMGPPLHFDWPWWCSISYFFFRHWHFHWTFHNWSEECKDFIKWCLCKDPKKRPTAEQILQHPWF
Kinase cmk-1.AA RSK 25-278 31 1.2e-93 317.45 In-house 1-278 (278) Show / Hide 
Range on Protein: 25-278
Range on HMM: 1-278/278
Sequence Identity: 31% (89 aa)

RDVLGTGAFSKVFLAESK--SDAGQMYAVKCIDKKALKGKE---ESLENEIKVLRKLR-HNNIVQLFDTYDEKQFVYLVMELVTGGELFDRIVAKGS---
  |||.|.. ||||   .  .|.|| ||.| ..|. .. ..   .    |...|   . | .||.|........ .||.||.. |||||...  ...   
LKVLGQGGYGKVFLCRKCTHHDTGQIYAMKVLKKAKIVQRQKDTRHTMTERNILERCQQHPFIVTLHYAFQTEGKLYLIMEYCRGGELFTHLQKEKHFGC

YTEQDASNLIRQVLEAVGFMHDNGVVHRDLKPENLLYYNQDED-SKIMISDFGLSKT---EDSGVMATACGTPGYVAPEVLQ---QKP-YGKAVDVWSIG
 .| .|.  ....  || ..|. |..|||||||| || ... .   |...|||..|    .... . | |.|  |.|||.|    |.  ..||.|.|| |
FSEDEACFYMAEIVLAVEHLHQQGIIHRDLKPENILYDDES-NEGHIKLTDFGFCKQFRCDHNQWTMTFCYTIEYMAPEMLKRANQQGGHDKACDWWSLG

VIAYILLCGYPPFYD---ESDANLFAQIIKGEYEFDAPYWDQISDSAKDFITHLMCCDPEARFT-----CQDALSHPWI
|. | .| |.|||.    .. . ....| ||.. .. | |. .|. |||.|..... ||. | .      .. ..|||.
VLMYEMLTGCPPFQGPNDNNRKEIMKRIQKGKFSLTMPNWQYLSQEAKDLIRKMLHRDPHKRLGCGPQDAEEIKQHPWF
Kinase cmk-1.AA TyrKc 22-273 20 4.6e-16 36.95 SMART 1-280 (280) Show / Hide 
Range on Protein: 22-273
Range on HMM: 1-280/280
Sequence Identity: 20% (59 aa)

YDFRDVLGTGAFSKVFLAESKSDAGQMYAVKCIDKKALKGKEESLENEIKVLRKL--RHNNIVQLF-DTYDEK------QFVYLVMELVTGGELFDRIVA
  . ..|| ||| .|.... |    .. |||.. . |    .| . .|.....||  .| |||.|.    ...      . ...|||.. .| | |.. .
ITLGKKLGEGAFGEVYKGTWK----IQVAVKMLKEDA----REDFMREARIMCKLGGHHPNIVRLYGVCTQQGRNFMYIEPLMIVMEYMPHGDLKDYLRK

KGS-YTEQDASNLIRQVLEAVGFMHDNGVVHRDLKPENLLYYNQDEDSKIMISDFGLSKTEDSG--------VMATAC--GTPG-----YVAPEVLQQKP
..   . .|  .   |. .   . |.....||||   | |. ..     . |||||||.  ...        .  ..   |. .       |||... . 
HRPKLCMKDLLSFCWQIACGMEYLHSKNCIHRDLAARNCLVGENH---TVKISDFGLSRDIYDDDQQGESKDYYRKKEHKGGKTMLPIRWMAPECINYGK

YGKAVDVWSIGVIAY-ILLCGYPPFYD-----ESDANLFAQIIKGEYEFDAPY-----WDQISDSAKDFITHLMCCDPEARF-----TCQDAL
.  . |||| ||  . |.  | .| ..      |.. ..... .|..    |.           ... .   ..|.. ..       .. . .
FTTKSDVWSFGVCMWEIFTYGQQPYPGMIQQMMSNQEVIEYVKQGYRMPQPPNDYPMSF--VCCPDEMYQIMKQCWHEDPEDRPTFSEIHECF
Kinase cmk-1.AA Pkinase_Tyr 22-145 26 1.8e-11 39.51 Pfam 1-137 (270) Show / Hide 
Range on Protein: 22-145
Range on HMM: 1-137/270
Sequence Identity: 26% (36 aa)

YDFRDVLGTGAFSKVFLAESK---SDAGQMYAVKCIDKKALKGKE---ESLENEIKVLRKL-RHNNIVQLFDTYD-EKQF--VYLVMELVTGGELFDRIV
  |  .|| ||| .|.... |   .. ..  |||.. |     ..   |.. .|.|....| .| |||.|      ...   .|.|||.. .| | |   
ITFGKKLGEGAFGEVYKGTWKGDPDNTKIPVAVKML-KEGAMHEQNCREDFMREAKIMKQLGHHPNIVRLYGVCTDQGEPNQIYIVMEYMPHGDLLDYLR

A----KGSYTEQDASNLIRQVLEAVGFMHDNGVVHRDL
.    |.. | .|  .  .|. ..  . .... .||||
KHREDKQPLTMKDLLQMCWQIAKGMEYLESKNCIHRDL