Gene EEED8.9 (Nematode worm)

EEED8.9

Species: Nematode worm
Alias: YQO9_CAEEL, CE28904, aSWK233, EEED8.9
External Links: Wormbase Link ,
Annotation: WormBase Physical Map location: II: 5395663-5393266, WormBase Genetic Map location: II:-1.49,

Classification

Group: Other
Family: NKF2

Sequence

Name Sequence Type Origin Length Description Download
EEED8.9.kin_dom Protein Kinase Domain Sugen global kinase HMM prediction 347 Kinase domain by global Sugen HMM Fasta, JSON
EEED8.9.AA Protein Genbank 641 None Fasta, JSON

Protein domain

Protein domains of EEED8.9.AA. The domains are annotated by HMM profiles from Pfam and SMART, as well as in-house data which includes HMMs of each individual kinase group, family and subfamily. Here is domain list in details, including sequence identity, significance and alignment. In particular, you can find can find the best hit kinase group/family/subfamily, which is helpful to understand the relationship between kinases.Kinase domain and best hit kinase group/family/subfamily are highlighted in red and blue. Visualized by pviz.

Usage: Zoom in selected region by dragging mouse and zoom out by double-clicking.

Show/hide domain list
Domain Protein name Domain Name Range Identity (%) Significance Score Profile Source Profile Range (length) Alignment
Kinase EEED8.9.AA NKF2 137-478 54 9.40000000001e-260 869.22 In-house 1-365 (365) Show / Hide 
Range on Protein: 137-478
Range on HMM: 1-365/365
Sequence Identity: 54% (200 aa)

YEFGEFLGQGCNAAVYSARLANSDAESSGNTHYGAGFNEVTNILAEIPPVSKVAQKKFPLAIKLMFNFEHDRDGDAHLLKSMGNELAPYPNAAKLLNGQM
||||.|.|||||||||.||..||...|.||.|||..|||..||||||||..|..|.|||||||.|.|||||||.||||.|.|.||..||.||.|...|||
YEFGQFIGQGCNAAVYEARMPNSPQHSEGNKHYGLIFNEGPNILAEIPPEQKPGQPKFPLAIKMMWNFEHDRDSDAHLNKMMQNEVPPYRNALKGEYGQM

G-----TFRPLPAKHPNVVRIQTAFIDSLKVLPDAIERYPDALHTARWYESIASEPKTMYVVMRRYRQTLHEYVWTR-HRNYWTGRVIIAQLLEACTYLH
.     ||...||.|||.|....||.||..|||||.|.|||.||...|.|... ...|||.||.|||.||..|.|.. |..|||....|||.||||..||
TYRRSRTFPKQPAPHPNIVCMFRAFCDSVRVLPDAHEDYPDMLHQRYWPEGYG-HNMTMYLVMKRYRCTLRQYLWMQCHPSYWTRMMMIAQMLEACDHLH

KHKVAQRDMKSDNILLEYDFDD-EIPQLVVADFGCALACDN--WQVDYESDEVSLGGNAKTKAPEIAT-AVPGKNVKVNFEMADTWAAGGLSYEVLTRSN
.|.||.|||||||||.|||||| ..|.||.|||||.|||..  ||..|.|..|..||||...||||.| |.||.|.....|.|||||.|...||.....|
QHGVAHRDMKSDNILVEYDFDDGACPWLVIADFGCCLACKHHGWQLPYSSWDVDRGGNACLMAPEIFTGAHPGCNHVHDYEKADTWACGAIAYEIFGQKN

PFYK------------LLDTAT--YQESELPALPSRVNFVARDVIFDLLKRDPNERVKPNIAANAL
|||.            .||...  |||..||..|.....|.|.....||.|||..|..|.||||.|
PFYSSSGGMAREQGEMHLDSCNSDYQEDQLPQMPQSCPPVLRQLVYNLLQRDPSKRPSPQIAANVL
Kinase EEED8.9.AA S_TKc 137-483 16 3.1e-13 17.27 SMART 1-231 (231) Show / Hide 
Range on Protein: 137-483
Range on HMM: 1-231/231
Sequence Identity: 16% (61 aa)

YEFGEFLGQGCNAAVYSARLANSDAESSGNTHYGAGFNEVTNILAEIPPVSKVAQKKFPLAIKLMFNFEHDRDGDAHLLKSMGNELAPYPNAAKLLNGQM
||... .|.|  . || .|  .                                  .   ||| .                            . .   .
YEILRKIGKGAFGKVYKCRHKK---------------------------------TGRIVAIKIIK---------------------------EHIRREI

GTFRPLPAKHPNVVRIQTAFIDSLKVLPDAIERYPDALHTARWYESIASEPKTMYVVMRRYRQ---TLHEYVWTRHR-------NYWTGRVIIAQLLEAC
   .    .|||.|..  .| |                             . .|.||    .   .|..|   | |       .  . | ...|...| 
QILKK---HHPNIVKLYDVFQD-----------------------------DHLYMVMEYCDGDLGDLFDYIKKRGRHGLRFPFPE-HARFYMYQICCAL

TYLHKHKVAQRDMKSDNILLEYDFDDEIPQLVVADFGCALACDNWQVDYESDEVSLGGNAKTKAPEIATAVPGKNVKVNFEMADTWAAGGLSYEVLTRSN
 |.|.|..  || | .||||         .. ..||| |               .. |     |||.         . ... .| |. | . || |..  
EYCHSHGIIHRDLKPENILLDE-------HIKICDFGLARQL-----------TTFCGTPWYMAPEVL--------GYGKCKCDWWSCGCILYEMLCGYP

PFYKLLDTATYQESELPALPSRVNFVARDVIFDLLKRDPNERVKPNIAAN----ALNLSLF
||.   . ....              |.| |  .|..||..|     | .    . .   |
PFP--QMQMMFKKIG--------SPEAKDFIRKCLQKDPEKRPTA-EALQDEWDIKCHPWF
Kinase EEED8.9.AA Ciliate-E2 318-483 17 3.4e-13 41.61 In-house 165-365 (365) Show / Hide 
Range on Protein: 318-483
Range on HMM: 165-365/365
Sequence Identity: 17% (40 aa)

IIAQLLEACTYLHKHK-VAQRDMKSDNILLEYDFDDEIPQLVVADFGCALACD-------------NWQVDYESDEVSLG---------------GNAKT
.||....|  |||. . .  || | .|||.          . ..||| .  .|             ...     .... |               |..  
YIACIILALEYLHSKNNIIHRDIKPENILF----------IKIIDFGLSKKYDDDNQNRTHKQQCKWYMF-KNDTSRTPGYMDQIIQQNMFNTICGTPGY

KAPEIATAVPGKN---VKVNFEMADTWAAGGLSYEVLTRSNPFYKLLDTATYQESELPALPSRVNFVARDVIFD--------------------------
.||||    .  |    |   ...| |..| . || |.   ||                     .    .. |.                          
MAPEILNGKKYDNQQKQKGYDYKCDIWSLGVILYEMLFGKPPF-------------------QQQIKQCKIDFPCPEWQKDTQCIQCKWKSWKKWSQECK

---------LLKRDPNERVKPNIAANALNLSLF
         .|..||..|     .  .||   |
DLIKKFGKRMLQKDPEKRIT--GWEQILNHPWF
Kinase EEED8.9.AA CAMK 316-365 32 1.1e-10 29.91 In-house 182-243 (425) Show / Hide 
Range on Protein: 316-365
Range on HMM: 182-243/425
Sequence Identity: 32% (20 aa)

RVIIAQLLEACTYLHKHKVAQRDMKSDNILLEYDFDDEIP------------QLVVADFGCA
| .. |...|  |.|.|... || | .|||| ...||. |            .. ..||| |
RRYFRQICSAVHYCHSHNIVHRDLKPENILLDDNNDDSDPVEHDEIFDWNNNNIKIIDFGFA
Kinase EEED8.9.AA PLK1 316-483 28 2.3e-10 30.03 In-house 102-253 (253) Show / Hide 
Range on Protein: 316-483
Range on HMM: 102-253/253
Sequence Identity: 28% (48 aa)

RVIIAQLLEACTYLHKHKVAQRDMKSDNILLEYDFDDEIPQLVVADFGCALACDNWQVDYE-SDEVSLGGNAKTKAPEIATAVPGKNVKVNFEMADTWAA
|  . |..|.| |||. |.  ||.|  |. |. ..     |. . ||| |      ...|.      |.|     |||. .     .    ||. | |. 
RYYMYQIVEGCQYLHNNKIIHRDLKLGNLFLNDHL-----QVKIGDFGLAT-----KCEYDGERKKTLCGTPNYIAPEVLN-----KKGHSFEV-DIWSI

GGLSYEVLTRSNPFYKLLDTATYQESELP--ALPSRVNFVARDVIFDLLKRDPNERVKPNIAANALNLSLF
| . | .|  . ||       ||.        .|| .. .|...|  .|. ||..|  |.| .  ||   |
GCIMYILLFGQPPFETKCLKETYSRIKKNEYRIPSHISQPAAQLIRKMLDPDPTRR--PTIEQ-VLNDEFF
Kinase EEED8.9.AA ULK 316-365 33 1.3e-09 29.85 In-house 133-189 (329) Show / Hide 
Range on Protein: 316-365
Range on HMM: 133-189/329
Sequence Identity: 33% (19 aa)

RVIIAQLLEACTYLHKHKVAQRDMKSDNILLEYDF---DDE----IPQLVVADFGCA
. .. |.|... .||||..  ||.| .|||.  ..   |..    ...| .|||| |
IQFFKQILNGFKELHKHNIIHRDIKPQNILIHNGQPKTDSKKVHPNGVLKIADFGFA
Kinase EEED8.9.AA ULK 316-365 31 2.4e-09 29.38 In-house 129-185 (324) Show / Hide 
Range on Protein: 316-365
Range on HMM: 129-185/324
Sequence Identity: 31% (18 aa)

RVIIAQLLEACTYLHKHKVAQRDMKSDNILLEYDF---DDE----IPQLVVADFGCA
. .. |..... .||||..  ||.| .|||.  ..   |..    ...| .|||| |
IQFFKQICNGFKELHKHNIIHRDIKPQNILIHNGQPKTDSKKVHPNGVLKIADFGFA
Kinase EEED8.9.AA CAMKL 316-363 33 7.9e-09 24.15 In-house 130-174 (297) Show / Hide 
Range on Protein: 316-363
Range on HMM: 130-174/297
Sequence Identity: 33% (16 aa)

RVIIAQLLEACTYLHKHKVAQRDMKSDNILLEYDFDDEIPQLVVADFG
| .  |...|  |.|.|... || | .|||| .. .    .. ..|||
RRYFRQIVSAVNYCHSHGIVHRDIKPENILLDENGNN---NIKIIDFG
Kinase EEED8.9.AA PDK1 320-349 40 1.3e-08 21.93 In-house 117-146 (307) Show / Hide 
Range on Protein: 320-349
Range on HMM: 117-146/307
Sequence Identity: 40% (12 aa)

AQLLEACTYLHKHKVAQRDMKSDNILLEYD
|... |. .||..... ||.| .||||  |
AEIIDALEHLHSNGIIHRDLKPENILLDKD
Kinase EEED8.9.AA Trio 319-365 34 1.5e-08 17.38 In-house 101-146 (258) Show / Hide 
Range on Protein: 319-365
Range on HMM: 101-146/258
Sequence Identity: 34% (16 aa)

IAQLLEACTYLHKHKVAQRDMKSDNILLEYDFDDEIPQLVVADFGCA
. |.|||  ||| . ..  | |..|.... .   . ||. ..||| |
MWQMLEAVHYLHNCHILHLDIKPENMMMWHYNAGR-PQIKICDFGDA
Kinase EEED8.9.AA CAMK-Unique 316-363 28 2.3e-08 23.48 In-house 160-218 (363) Show / Hide 
Range on Protein: 316-363
Range on HMM: 160-218/363
Sequence Identity: 28% (17 aa)

RVIIAQLLEACTYLHKHKVAQRDMKSDNILLEYDFDD-----------EIPQLVVADFG
. |...||.|  |.|. ..  || | .||.. | |.|               ....|||
CFIMQCLLSAVAYMHSQDIVHRDLKLENIMVCYSFKDNNHHRDFPYDWSNWHIKLCDFG
Kinase EEED8.9.AA Pkinase 245-365 22 1e-06 24.51 Pfam 58-159 (293) Show / Hide 
Range on Protein: 245-365
Range on HMM: 58-159/293
Sequence Identity: 22% (30 aa)

KHPNVVRIQTAFIDSLKVLPDAIERYPDALHTARWYESIASEPKTMYVVMRRYRQ-----TLHEYVW-TRHRNY----WTGRVIIAQLLEACTYLHKHKV
.|||.||.  .| |                            .. .|.||   .       |..|.   ||...    |. . .. |.|..  |.|....
NHPNIVRLYDWFED----------------------------KDHIYMVMEYCEGGLYVMDLFDYISTWRHGCFYFSEWECKFYMYQILRGLEYCHSMGI

AQRDMKSDNILLE--YDFDDEIPQLVVADFGCA
  ||.|..|||.   .. |.    . ..|||.|
IHRDLKPENILIDNNGHIDA---CVKICDFGLA
Kinase EEED8.9.AA Ciliate-E2 137-152 43 0.022774 3.92 In-house 1-16 (365) Show / Hide 
Range on Protein: 137-152
Range on HMM: 1-16/365
Sequence Identity: 43% (7 aa)

YEFGEFLGQGCNAAVY
|.| . .|||. . ||
YKFIKKIGQGNFGSVY
Kinase EEED8.9.AA Trio 409-429 42 0.060559 0.05 In-house 181-201 (258) Show / Hide 
Range on Protein: 409-429
Range on HMM: 181-201/258
Sequence Identity: 42% (9 aa)

ADTWAAGGLSYEVLTRSNPFY
.|.|..| |.|  |. . |||
TDIWSIGVLTYVMLSGISPFY
Kinase EEED8.9.AA Pkinase 137-159 26 0.638151 4.34 Pfam 1-23 (293) Show / Hide 
Range on Protein: 137-159
Range on HMM: 1-23/293
Sequence Identity: 26% (6 aa)

YEFGEFLGQGCNAAVYSARLANS
|..|. .|.|  . || ..  ..
YHIGRKIGSGSFGCVYKCHHKGT
Kinase EEED8.9.AA Pkinase 453-483 29 2.673563 2.14 Pfam 266-293 (293) Show / Hide 
Range on Protein: 453-483
Range on HMM: 266-293/293
Sequence Identity: 29% (9 aa)

ARDVIFDLLKRDPNERVKPNIAANALNLSLF
..|.| ..|..||..|     |. .|.   |
CKDFIKWCLCKDPKKRPT---AEQILQHPWF