Gene F22B3.8 (Nematode worm)

F22B3.8

Species: Nematode worm
Alias: aSWK359, CE03259, F22B3.8
External Links: Wormbase Link ,
Annotation: WormBase Physical Map location: IV: 11424468-11422657, WormBase Genetic Map location: IV:4.97,

Classification

Group: TK
Family: Fer

Sequence

Name Sequence Type Origin Length Description Download
F22B3.8.kin_dom Protein Kinase Domain Sugen global kinase HMM prediction 306 Kinase domain by global Sugen HMM Fasta, JSON
F22B3.8.AA Protein Genbank 484 None Fasta, JSON

Protein domain

Protein domains of F22B3.8.AA. The domains are annotated by HMM profiles from Pfam and SMART, as well as in-house data which includes HMMs of each individual kinase group, family and subfamily. Here is domain list in details, including sequence identity, significance and alignment. In particular, you can find can find the best hit kinase group/family/subfamily, which is helpful to understand the relationship between kinases.Kinase domain and best hit kinase group/family/subfamily are highlighted in red and blue. Visualized by pviz.

Usage: Zoom in selected region by dragging mouse and zoom out by double-clicking.

Show/hide domain list
Domain Protein name Domain Name Range Identity (%) Significance Score Profile Source Profile Range (length) Alignment
SH2 F22B3.8.AA SH2 9-132 23 1e-15 59.47 SMART 1-87 (87) Show / Hide 
Range on Protein: 9-132
Range on HMM: 1-87/87
Sequence Identity: 23% (30 aa)

YQFFHGFVLQELQLILLKTN----GDFLLRLSHQPEKNAKKPTTPDKSATDPIPLTRVILVLSVNITQKTGTTRSFYGDLEDVKKENMDMHLFIEETAGK
....||..  |    |||..    ||||.| | .                     ..  .||||                      .   |  |....  
QPWYHGNISREEAEQLLKNPGMPDGDFLVRDSES---------------------NPGDYVLSVRWK-------------------GKVKHYRIRRNDD-

WTSFYIER--RFKFPTIDELINYYKVNPIC
  ..||.   | |||.. ||.|.|. ||. 
-GKYYIDETWRRKFPSL-ELVNHYQHNPLG
Kinase F22B3.8.AA Fer 156-440 39 7.4e-127 427.75 In-house 1-283 (283) Show / Hide 
Range on Protein: 156-440
Range on HMM: 1-283/283
Sequence Identity: 39% (120 aa)

IDMTPKKLGEGAFGIVYLGRWAQPFSVDQKE-FHKWCDV---AVKTVKN---DDSRAALLEVMHEARLQLQ-LRHKNVLAFRGVFLLKKPIMLVSEFCEK
.... |||||||||.||.||     . ..|.  .||..|   |||..|.   |.... . |.|||||. .. . |.|| .|.||  .. |||.| |||  
VTLG-KKLGEGAFGEVYKGR-----R-TLKCKKGKWHVVNKVAVKVKKCKCEDATKEQIKEFMHEARIMRNNYDHPNVVKFYGVCVDEQPIMIVMEFCNG

KLFENHFPYGSLKDYLQKSK---VSVDEKLRFCLGSSCGLEYIHFKGLIHRDLATRNILVSADKT---PKIADFGLAKH----ASSYKMR-KATKIPVRY
         |||..||.|.|   ||..||.|.|....||.||.| |. ||||.| ||.|...||.   .||.|||....     ..|||. ||.|.|.|.
---------GSLDSYLKKNKNKTVSDNEKIRMCYQAACGMEYLHSKNCIHRDIAARNCLYHKDKVKKKCKISDFGMSRQCSDYGYDYKMKEKACKVPIRW

LAPETLSSFVYSTKTDVYTFGLVIWEIFANGQEPYMKAQPHQECVAPKNTQLRGRHIKELIRKELFVKFNQEAPVALQQYVAAKLFVVDDKKRPDMPEVG
|||||.....||.||||..|| ..||||.||.|||.  ||| .   .|.|.......|  |.|. . .. ...|... |..... ...|...|| | |. 
LAPETWQTGIYSPKTDVWSFGVMCWEIFTNGAEPYPG-QPH-G---MKMTNVKKQARKWIIKKGYMMPMPNHMPPEIMQIMMKQCWQKDPEDRPTMKEIC

VTSN
 . .
QKLK
Kinase F22B3.8.AA TK 161-371 21 1.2e-71 239.28 In-house 5-395 (486) Show / Hide 
Range on Protein: 161-371
Range on HMM: 5-395/486
Sequence Identity: 21% (87 aa)

KKLGEGAFG---IVYLGRWAQPFSVDQKEFHK---------------WCDVAVKTVK---NDDSRAALLEVMH----------EARLQLQLR-----HKN
||||||.||    ||.|.| ..   . |.|..                ..||||..|   ...... ..|.||          ||.   ...     |.|
KKLGEGQFGSFGEVYKGEWRGRNPWNGKRFPCHMTVTLKCKNGKEGGKTPVAVKMLKEGDAMSQEEFFDEEMHDRDGGEDFLEEAEEMKMMCHSLGHHPN

VLAFRGVFLLK------------KPIMLVSEFCEK--KLFENHFPYGSLKDYLQKSK-------------------------------------------
.. . || . .            .|.|.| |....  .       .|||.|||.|..                                           
IVRLYGVCTQGEPKPCFEVVVHQEPWMIVMEYMPHGDM-------DGSLRDYLRKCRPKFQHEQDCPDNQHNKYPPSKLHHCMKGDITYSHESNSPCPEE

----------------------------------VSVDEKLRFCLGSSCGLEYIHFK------GLIHRDLATRNILVSADKT-----------PKIADFG
                                  ... ..| .|.  .||.||.| |      ...|||||.||.||. ...            ||||||
QDYDDDLIKDHPPPLTTKDLLQMAWQWCLTCKHQLTMHQLL-MCWQIACGMEYLHSKNCEFIQNFVHRDLAARNCLVGENNVCKWHFDGCGPVCKIADFG

LAKH-----------------------------------ASSYKMRKATKIPVRYLAPETLSSFV---------YSTKTDVYTFGLVIWEIFANGQEPY
|...                                    . |.... .|.|.|..|||.| . |         ..||.||. || ..|||| .|||||
LSRQGSGVLARDIYSDDDYYRKSSYGTGRPMWPFEDDPWQDYYRQQSGGKLPIRWMAPECLNDRVFSEAEKYGKFTTKSDVWSFGVLMWEIFTYGQEPY
Kinase F22B3.8.AA Pkinase_Tyr 156-371 34 3.4e-67 228.18 Pfam 1-216 (270) Show / Hide 
Range on Protein: 156-371
Range on HMM: 1-216/270
Sequence Identity: 34% (81 aa)

IDMTPKKLGEGAFGIVYLGRWAQPFSVDQKEFHKWCDVAVKTVKNDDSRAA--LLEVMHEARLQLQL-RHKNVLAFRGVFL-LKKP--IMLVSEFCEKKL
| .  ||||||||| ||.|.|        ..  . ..||||..|.. .  .  . . |.||..  || .|.|.. . || .  ..|  |..| |...   
ITFG-KKLGEGAFGEVYKGTWKG------DPDNTKIPVAVKMLKEGAMHEQNCREDFMREAKIMKQLGHHPNIVRLYGVCTDQGEPNQIYIVMEYMP---

FENHFPYGSLKDYLQKS-----KVSVDEKLRFCLGSSCGLEYIHFKGLIHRDLATRNILVSADKTPKIADFGLAK---HASSY-KMRKATKIPVRYLAPE
      .|.|.|||.|      .... ..| .|.  ..|.|| . |..||||||.||.||. ... ||.|||||.   . . | ..|. .|.|.. .|||
------HGDLLDYLRKHREDKQPLTMKDLLQMCWQIAKGMEYLESKNCIHRDLAARNCLVTENNVVKICDFGLARDIYNDDYYYRKRGGGKLPIKWMAPE

TLSSFVYSTKTDVYTFGLVIWEIFANGQEP-Y
 ..  ...||.||. || ..||||  |..| |
CINYGKFTTKSDVWSFGVLMWEIFTYGEQPTY
Kinase F22B3.8.AA TyrKc 157-450 28 3.8e-67 230.31 SMART 1-280 (280) Show / Hide 
Range on Protein: 157-450
Range on HMM: 1-280/280
Sequence Identity: 28% (95 aa)

DMTPKKLGEGAFGIVYLGRWAQPFSVDQKEFHKWCDVAVKTVKNDDSRAALLEVMHEARLQLQL--RHKNVLAFRGVFLLK-------KPIMLVSEFCEK
    |||||||||.||.|.|               .||||..|.|     . . |.|||.  .|  .|.|.... || . .       .|.|.| |... 
ITLGKKLGEGAFGEVYKGTWK-------------IQVAVKMLKEDA----REDFMREARIMCKLGGHHPNIVRLYGVCTQQGRNFMYIEPLMIVMEYMP-

KLFENHFPYGSLKDYLQKSK--VSVDEKLRFCLGSSCGLEYIHFKGLIHRDLATRNILVSADKTPKIADFGLAKHASSY--------KMRK----ATK--
        .|.|||||.|..  ......| ||.  .|| ||.| |..||||||.||.||....| ||.||||..   ..          ||     .|  
--------HGDLKDYLRKHRPKLCMKDLLSFCWQIACGMEYLHSKNCIHRDLAARNCLVGENHTVKISDFGLSRDIYDDDQQGESKDYYRKKEHKGGKTM

IPVRYLAPETLSSFVYSTKTDVYTFGLVIWEIFANGQEPYMK-AQPHQECVAPKNTQLRGRHIKELIRKELFVKFNQE--------APVALQQYVAAKLF
.|.| .|||..   ...||.||. || ..|||| .||.||   .|            .  ... |....    .  ..        .| .. | .  .  
LPIRWMAPECINYGKFTTKSDVWSFGVCMWEIFTYGQQPYPGMIQQ----------MMSNQEVIEYVKQGYRMPQPPNDYPMSFVCCPDEMYQ-IMKQCW

VVDDKKRPDMPEVGVTSNSSAPYDVSGI
  | ..|| . |.           .. .
HEDPEDRPTFSEI-----------HECF
Kinase F22B3.8.AA UTK 158-371 29 3.9e-49 166.24 In-house 2-241 (296) Show / Hide 
Range on Protein: 158-371
Range on HMM: 2-241/296
Sequence Identity: 29% (75 aa)

MTPKKLGEGAFGIVYLGRWAQPFSVDQKEFHKWCDVAVKTVKNDDS-RAALL---EVMHEAR---LQLQLR-HKNVLAFRGVFLLKKPIMLVSEFCEKKL
. ...||.||||.|...|.     .. .|  .  |||||. ..... . .     ..| |||   .  |.. | ||| . || .  .|.|.|.|..|.  
QLGRQLGQGAFGEVHKARF-----TQCSEHMYEMDVAVKVCQHHADAQQEPEPYPDFMEEARELQMMKQFHWHPNVLRLVGVCTQEEPWMIVTEYMEN--

FENHFPYGSLKDYLQKSKVSVD---------EKLRFCLGSSCGLEYIHFKGLIHRDLATRNILVSAD-------KTPKIADFG---LAKHASS-------
       |.| .||.... ...         ..| ...  ..|..|.| .|..||||| ||.|| ..        . ||||||   ... ...       
-------GDLRSYLRRHRPTPPACPHWLTLHQRLCMAWDIARGMQYLHSCGFVHRDLAARNCLVHMHRMMWHCMMVCKIADFGRGGMSRRVNTFHFSNRY

----YKMRK-ATKIPVRYLAPETLSSF-VYSTKTDVYTFGLVIWEIFANGQEPY
    | |.  ....|.|  ||| | .   ..||.||. || | |||...|. ||
WESYYYMAQHQDRWPIRWMAPEALTHHTRFTTKSDVWSFGVVCWEIWTWGRLPY
Kinase F22B3.8.AA TK-Unique 161-371 29 6.4e-41 138.87 In-house 5-240 (294) Show / Hide 
Range on Protein: 161-371
Range on HMM: 5-240/294
Sequence Identity: 29% (74 aa)

KKLGEGAFGIVYLGRWAQPFSVDQKEFHKWCDVAVKTVKNDDSRAALLEVMHEARLQLQLR-HKNVLAFRGVFLLKK-PIMLVSEFCEKKLFENHFPYGS
...|||||| |. |   ..     |.. |   ||||..| . .     . . |...  .|  |.|.. . |.   .  | |.. |.|         |.|.
DVIGEGAFGQVWRGEVWGIW----KHWDKQKCVAVKMLKDNATDTDKQDFLKEIQMMKELGDHPNIVQCLGCCTKSDEPWMIIMEYC---------PCGN

LKDYLQKSK---------------------------VSVDEKLRFCLGSSCGLEYIHF--KGLIHRDLATRNILVSADKTPKIADFGLAKHASS---YKM
| .||....                           .|    ..|. .  ||.||..   |. .||||..||.|.. ||. ||.|||.|.. .    | |
LQHYLRTCRPAMRQHQTYGNLKFDFHHMPDKPRTEPISPKDLYHFAWQIACGMEYLASQRKKIVHRDLCARNVLLTEDKVCKICDFGMARDVYTNGVYSM

R-KATKIPVRYLAPETLS--SFVY-STKTDVYTFGLVIWEIFANGQEPY
  .  .||.|..||| |.    .| .||.||. || ..|||| .|. ||
MCSQGRIPIRWMAPESLKCYHGMYHTTKSDVWSFGVLMWEIFTLGACPY
Kinase F22B3.8.AA TKL 163-365 23 2.1e-40 140.56 In-house 1-284 (364) Show / Hide 
Range on Protein: 163-365
Range on HMM: 1-284/364
Sequence Identity: 23% (71 aa)

LGEGAFGIVYLGRWAQ-----PFSVDQKEFHKWCDVAVKTVKNDD--------------------------SRAALLEVMHEARLQLQLRHKNVLAFRGV
.|.|.||.|| |.| .     |         .  |||||. | ..                          .. .  .   |... ..||| |.. | |.
IGSGGFGEVYKGKWRGWGGKCP------S-DTGKDVAVKKFKSHNDDEFTKNSQENNDNNNYSDMQLNDPEASWFRFFEEEEIMMMSRLRHPNIVQFMGY

FLLKKP-------------IMLVSEFCEKKLFENHFPYGSLKDYLQKSKVSVDEKLRFCLGSSCGLEYIHF--------KGLIHRDLATRNILVSADKT-
 .  ..             ...| |.|..         ||| .||.      . ..|..|. ..|..| |         ...||||| ..||||  . | 
CCCPPCGCVCMHPVGPWGQLCIVMEYCPG---------GSLLHYLH-----WHQRCRWALDIARGMNYLHSMNPKWCTKPPIIHRDLKSKNILVDENWTN

-------------PKIADFGLAKHASSYKM-------------------RKATKI-PVRYLAPETLS----------------SFVYSTKTDVYTFGLVI
             .||.||||..  |  .                    .. |..   |..||| |                 .| ||.|.||| ||.|.
VSNYMYNPNADWCCKICDFGLSRFMSQSGNMNDTMTTMMESAEHQNNRKTTMTQCGTPRWMAPEVLRGQMNYTEKVGIDEFCKGFEYSEKCDVYSFGIVL

WEIFA
|||..
WEILT
Kinase F22B3.8.AA RTKC 193-371 38 1.7e-39 127.95 In-house 31-208 (261) Show / Hide 
Range on Protein: 193-371
Range on HMM: 31-208/261
Sequence Identity: 38% (73 aa)

VAVKTVKNDDSRAALLEVMHEARLQLQLRHKNVLAFRGVFLLKKPIMLVSEFCEKKLFENHFPYGSLKDYLQKS-KVSVDEKLRFCLGSSCGLEYIHFKG
||.|  . . .  .  |   ||    |..|.||    ||    |||  | ||||         .||||.|| .  ...   |.|||.  . |.| || .|
VACKSLHHTAMDNDRQELLEEAAVMAQFEHPNVVHLIGVVTVGKPILVVLEFCE---------RGSLKSYLMNNPDCTEHQKVRFCYQCASGMEHIHSFG

LIHRDLATRNILVSADKTPKIADFGLA--K------HASSYKMRKATKIPVRYLAPETLSSFVYSTKTDVYTFGLVIWEIFANGQEPY
 ||||.| ||.|.|.|.| |.||||||         |.  | .|    .|||  ||| |     | |.||  ||    ||. ... ||
FIHRDVAARNVLLSSDLTCKVADFGLARESPCNDDSHEAYYRSR-SGNLPVRWTAPEALDDRKFSEKSDVWAFGILMYEIYTKAEMPY
Kinase F22B3.8.AA Src 156-371 30 2.5e-37 124.33 In-house 1-201 (255) Show / Hide 
Range on Protein: 156-371
Range on HMM: 1-201/255
Sequence Identity: 30% (69 aa)

IDMTPKKLGEGAFGIVYLGRWAQPFSVDQKEFHKWCDVAVKTVKNDDSRAALLEVMHEARLQLQLRHKNVLAFRGVFLLKKPIMLVSEFCEKKLFENHFP
| .  .|||.| || |. | |            .  .||||| | ..   .      || .  .|||.....   |   ..||  | |. ..        
IKLC-RKLGQGQFGEVWMGYW-----------NGNTKVAVKTLKPGT--MSPEAFLQEAQIMKKLRHEKLVQLYAVCSQEEPIYIVTEYMSH--------

YGSLKDYLQK----SKVSVDEKLRFCLGSSCGLEYIHFKGLIHRDLATRNILVSADKTPKIADFGLAKHAS----SYKMRKATKIPVRYLAPETLSSFVY
 ||| |||.|    ..... . . .    . | .|.  . .|||||| ||.||. .   |.||||||.        | .|.  |.|..  ||| ..  ..
-GSLLDYLKKDGEGRHLHLPQLIDMAAQVAEGMAYLESMNYIHRDLAARNVLVGENNVCKVADFGLARLIKEDDDEYCARHGAKFPIKWTAPEAINYGRF

STKTDVYTFGLVIWEIFANGQEPY
..|.||  ||  ..||.  |. ||
TIKSDVWSFGILLTEIVTYGRVPY
Kinase F22B3.8.AA HMTK 158-371 30 1.4e-33 114.47 In-house 1-235 (291) Show / Hide 
Range on Protein: 158-371
Range on HMM: 1-235/291
Sequence Identity: 30% (74 aa)

MTPKK-LGEGAFG-----------------IVYLGRWA-QPFSVDQKEFHKWCD-VAVKTVKNDDSRAALLEVMHEARLQLQLRHKNVLAFRGVFLLKKP
 ...| .| | ||                  |||. |. ..  .| |.  .    .|||....| | .   | ..|| . .|||| |.. . || . ..|
LKAIKVIGAGQFGMVQCLRLAPPDEGCTSLKVYLAEWSVKD--GDGKDDSNQPHHRAVKMLRGDASHEDREEFLREAEVMCQLRHPNLVQLVGVCMQQRP

IMLVSEFCEKKLFENHFPYGSLKDYLQ-----KSKVSVDEKLRFCLGSSCGLEYIHFKGLIHRDLATRNILVSADKTPKIADFGLA----KHASSYKMRK
 ..| |..         .|| |.. |.     . ...  | | ||   . |..||. ....|.|||.||.||.     |||||||.    ..   .. ||
WLCVLEYM---------QYGDLRNVLKTCREKNIQLTYHEQLYFCVQCASGMAYIASQRMVHMDLAARNCLVGHNNQVKIADFGLTRRLDPGQDYWHLRK

AT-KIPVRYLAPETLS--SFVYSTKTDVYTFGLVIWEIFANGQEPY
.  | |....|||...    . | |.||. || . |||.. |  ||
HMVKLPIKWMAPEAMDGKRKIFSEKSDVWAFGVTMWEIWMYGEQPY
Kinase F22B3.8.AA Ack 156-378 29 1.8e-33 110.29 In-house 1-219 (266) Show / Hide 
Range on Protein: 156-378
Range on HMM: 1-219/266
Sequence Identity: 29% (70 aa)

IDMTPKKLGEGAFGIVYLGRWAQPFSVDQKEFHKWCDVAVKTVKND--DSRAALLEVMHEARLQLQLRHKNVLAFRGVFL-LKKPIMLVSEFCEKK-LFE
| .  .|||.| ||.|  | | .| .       |   |||| .. |   .  .. . . |.   ..|.| ...   || |  .. .|.|.|...   | .
ITLC-EKLGDGCFGVVWRGEWTNPGG-------KHIQVAVKCLRSDKMQQPNCMDDFLREVAIMHSLDHPHLVRLYGVVLDQPM-LMMVTELAPCGSLLD

NHFPYGSLKDYLQKSKVSVDEKLRFCLGSSCGLEYIHFKGLIHRDLATRNILVSAD-KTPKIADFGLA---KHASS-YKMRKAT--KIPVRYLAPETLSS
.      |.. .  .. ..   ..||.    |. | . |..||||||.||||. .| .. ||.||||    . .   |.|      |.|    ||| |  
C------LRKHCRTAFFLIHTLCDFCMQIAMGMRYLEMKRCIHRDLAARNILLFSDDRKVKICDFGLMRALGQNEDYYRMEFHRNLKVPFAWCAPECLRH

FVYSTKTDVYTFGLVIWEIFANGQEPYMKAQPHQ
   | . ||  ||  .|| |  |.||.    . |
RQFSHASDVWMFGVTLWEMFSYGEEPWAGCNGYQ
Kinase F22B3.8.AA Csk 193-371 37 1.5e-32 108.43 In-house 25-198 (251) Show / Hide 
Range on Protein: 193-371
Range on HMM: 25-198/251
Sequence Identity: 37% (69 aa)

VAVKTVKNDDSRAALLEVMHEARLQLQLRHKNVLAFRGVFLLKK-PIMLVSEFCEKKLFENHFPYGSLKDYL---QKSKVSVDEKLRFCLGSSCGLEYIH
|||| .|.| . ...   . ||    ||||.|  .. || | .|  . .| |.  |         |.| |||    .. .. .. | | .    | .|  
VAVKCIKCD-GNGMAQAFLAEASVMTQLRHPNLVQLIGVILHQKNHLYIVMEYMSK---------GNLVDYLRSRGRHVITRRQLLKFAMDVCEGMCYLE

FKGLIHRDLATRNILVSADKTPKIADFGLAKHASSYKM-RKATKIPVRYLAPETLSSFVYSTKTDVYTFGLVIWEIFANGQEPY
 | ..||||| |||||| |   |. |||||| ..|        |.|.   ||| |    .||| ||  ||  .|||.  |  ||
QKKFVHRDLAARNILVSEDCVAKVSDFGLAKEECSQQDDSTSGKFPIKWTAPEALRHKKFSTKSDVWSFGILLWEIYSFGRVPY
Kinase F22B3.8.AA Pkinase 161-371 28 1.8e-28 101.76 Pfam 5-212 (293) Show / Hide 
Range on Protein: 161-371
Range on HMM: 5-212/293
Sequence Identity: 28% (64 aa)

KKLGEGAFGIVYLGRWAQPFSVDQKEFHKWCDVAVKTVKNDDSRAALLEVMH----EARLQLQLRHKNVLAFRGVFLLKKPIMLVSEFCEKKLFENHFPY
.|.|.|.|| ||....      ..|       ||||..| . ..    .. |    |... . |.|.|.. ....|  |. | .| |.||. | . ..  
RKIGSGSFGCVYKCHHK----GTGK------IVAVKIIKKR-HEKSWKDQTHRRLSEIQIMKRLNHPNIVRLYDWFEDKDHIYMVMEYCEGGL-Y-VM--

GSLKDYLQ---KSKV--SVDEKLRFCLGSSCGLEYIHFKGLIHRDLATRNILVSADKTP----KIADFGLAKH--ASSYKMRKATKIPVRYLAPETLS-S
 .|.||..   . ..  | .|  ....   .||||.| .| |||||   |||.. . ..    ||.||||||.    ..   .      .|.||| .  .
-DLFDYISTWRHGCFYFSEWECKFYMYQILRGLEYCHSMGIIHRDLKPENILIDNNGHIDACVKICDFGLAKQFDY-NNS-MTTFCGTPWYMAPEVIRGG

FVYSTKTDVYTFGLVIWEIFANGQEPY
  |..| |.. .|....| .  |. |.
QYYGPKVDMWSCGCILYEMLC-GRPPF
Kinase F22B3.8.AA S_TKc 157-441 22 2.8e-28 101.17 SMART 1-231 (231) Show / Hide 
Range on Protein: 157-441
Range on HMM: 1-231/231
Sequence Identity: 22% (67 aa)

DMTPKKLGEGAFGIVYLGRWAQPFSVDQKEFHKWCDVAVKTVKNDDSRAALLEVMHEARLQLQLRHKNVLAFRGVFLLKKPIMLVSEFCEKKLFENHFPY
    .|.|.|||| ||..|.                ||.| .|          .. | ..  . .|.|.  . .||   . . .| |.|.  |       
YEILRKIGKGAFGKVYKCRHKK----------TGRIVAIKIIK--------EHIRREIQILKK-HHPNIVKLYDVFQD-DHLYMVMEYCDGDL-------

GSLKDYLQKSK-------VSVDEKLRFCLGSSCGLEYIHFKGLIHRDLATRNILVSADKTPKIADFGLAKHASSYKMRKATKIPVRYLAPETLSSFVYST
|.|.||..| .        .  .  ...    |.|||.| .| |||||   |||..   . ||.|||||..       .       |.||| |    |..
GDLFDYIKKRGRHGLRFPFPE-HARFYMYQICCALEYCHSHGIIHRDLKPENILLDE--HIKICDFGLARQL------TTFCGTPWYMAPEVL---GYGK

-KTDVYTFGLVIWEIFANGQEPYMKAQPHQECVAPKNTQLRGRHIKELIRKELFVKFNQEAPVALQQYVAAKLFVVDDKKRPDMPEVGV-------TSNS
 | |.. .| ...| .. |. |.                    .......| .        .  . .    |....| .|||   |.             
CKCDWWSCGCILYEMLC-GYPPFP-------------------QMQMMFKKIG--------SPEAKD-FIRKCLQKDPEKRPTA-EALQDEWDIKCHPWF
Kinase F22B3.8.AA RTKC 163-172 90 0.016429 3.96 In-house 7-16 (261) Show / Hide 
Range on Protein: 163-172
Range on HMM: 7-16/261
Sequence Identity: 90% (9 aa)

LGEGAFGIVY
|| |||||||
LGRGAFGIVY