Gene F26E4.5 (Nematode worm)

F26E4.5

Species: Nematode worm
Alias: aSWK371, F26E4.5, CE09689
External Links: Wormbase Link ,
Annotation: WormBase Physical Map location: I: 9779116-9776995, WormBase Genetic Map location: I:3.95,

Classification

Group: TK
Family: Fer

Sequence

Name Sequence Type Origin Length Description Download
F26E4.5.kin_dom Protein Kinase Domain Sugen global kinase HMM prediction 264 Kinase domain by global Sugen HMM Fasta, JSON
F26E4.5.AA Protein Genbank 474 None Fasta, JSON

Protein domain

Protein domains of F26E4.5.AA. The domains are annotated by HMM profiles from Pfam and SMART, as well as in-house data which includes HMMs of each individual kinase group, family and subfamily. Here is domain list in details, including sequence identity, significance and alignment. In particular, you can find can find the best hit kinase group/family/subfamily, which is helpful to understand the relationship between kinases.Kinase domain and best hit kinase group/family/subfamily are highlighted in red and blue. Visualized by pviz.

Usage: Zoom in selected region by dragging mouse and zoom out by double-clicking.

Show/hide domain list
Domain Protein name Domain Name Range Identity (%) Significance Score Profile Source Profile Range (length) Alignment
SH2 F26E4.5.AA SH2 89-171 32 9.3e-26 92.81 SMART 1-87 (87) Show / Hide 
Range on Protein: 89-171
Range on HMM: 1-87/87
Sequence Identity: 32% (29 aa)

EPFYHGYMSREESEKLVRSQ----GEFLLRKTELTKRGEVVVLSVFWDEGVHHLVVEKANNGLYYLKE---FCFENISDLVRYHHQTRAS
.|.||| .|||| |.| ...    | ||.|  |        ||||.|...|.| .... ..| ||. |    .|... .||....... .
QPWYHGNISREEAEQLLKNPGMPDGDFLVRDSES--NPGDYVLSVRWKGKVKHYRIRRNDDGKYYIDETWRRKFPSL-ELVNHYQHNPLG
SH2 F26E4.5.AA SH2 91-165 31 6.9e-20 60.22 Pfam 1-81 (81) Show / Hide 
Range on Protein: 91-165
Range on HMM: 1-81/81
Sequence Identity: 31% (26 aa)

FYHGYMSREESEKLVRS----QGEFLLRKTELTKRGEVVVLSVFWDE---GVHHLVVEKANNG-LYYLKEFCFENISDLVRYH
.||| .||.| |.| ..     | ||.|. |  . |.  .|||..|     |.| .. . .|| .|.  . .|.....|| ..
WYHGKISRQEAERLLMNPGNPDGTFLVRESES-TPGD-YTLSVRDDGPGDRVKHYRIQRTDNGGYYITGRHKFCSLQELVEHY
Kinase F26E4.5.AA Fer 195-451 38 7.1e-137 461.02 In-house 1-283 (283) Show / Hide 
Range on Protein: 195-451
Range on HMM: 1-283/283
Sequence Identity: 38% (110 aa)

INLGKKLGNGEFGEVFQG------VLSVGIFTNDVEVAVKTMKGSKVTADERITFLREANLMLK-LNHKYVVRLYGVATQQEPIMIVMELCSGGCLKSRI
..||||||.| ||||..|       .......|.|.|.||..|....|..... |..||..|.. ..|..||..|||.....|||||||.|.||.|.|..
VTLGKKLGEGAFGEVYKGRRTLKCKKGKWHVVNKVAVKVKKCKCEDATKEQIKEFMHEARIMRNNYDHPNVVKFYGVCVDEQPIMIVMEFCNGGSLDSYL

EKKDEQ-LSDVLKRKYCKQIAKGMRYLEKKQVIHRDLAARNVLLDK-SDNCK--ISDFGLSLFGKLHKEQKLMK-----VPIRWLAPETLLKGIYSSKSD
 |.... .||  | ..| |.|.||.||..|..||||.||||.|..|  ...|  |||||.|  .. ......||     ||||||||||. .||||.|.|
KKNKNKTVSDNEKIRMCYQAACGMEYLHSKNCIHRDIAARNCLYHKDKVKKKCKISDFGMSRQCSDYGYDYKMKEKACKVPIRWLAPETWQTGIYSPKTD

VWSFGVVMFEVFS-GEYPYAD------VKVL-KELRRKVAHENLRLKPPSDMPTDDAKVME-MCFE-PVDNRATFVQVCNRYK
||||||...|.|. |..||..      .... |..|....... ....|. ||.. ...|. .|..   ..|.|. ..|...|
VWSFGVMCWEIFTNGAEPYPGQPHGMKMTNVKKQARKWIIKKGYMMPMPNHMPPEIMQIMMKQCWQKDPEDRPTMKEICQKLK
Kinase F26E4.5.AA TyrKc 195-450 37 1.4e-111 377.93 SMART 1-280 (280) Show / Hide 
Range on Protein: 195-450
Range on HMM: 1-280/280
Sequence Identity: 37% (110 aa)

INLGKKLGNGEFGEVFQGVLSVGIFTNDVEVAVKTMKGSKVTADERITFLREANLMLKL--NHKYVVRLYGVATQQ-------EPIMIVMELCSGGCLKS
| ||||||.|.||||..|...       ..||||..| ..     |  |.|||..| ||  .|. .||||||.|||       ||.|||||....|.||.
ITLGKKLGEGAFGEVYKGTWK-------IQVAVKMLKEDA-----REDFMREARIMCKLGGHHPNIVRLYGVCTQQGRNFMYIEPLMIVMEYMPHGDLKD

RIEKKDEQLSDVLKRKYCKQIAKGMRYLEKKQVIHRDLAARNVLLDKSDNCKISDFGLSLFGKLH-------KEQK-----LMK--VPIRWLAPETLLKG
.. |. ..|.   . ..| |||.||.||..|..|||||||||.|...   .|||||||| ... .       .  .       |  .||||.|||.. .|
YLRKHRPKLCMKDLLSFCWQIACGMEYLHSKNCIHRDLAARNCLVGENHTVKISDFGLSRDIYDDDQQGESKDYYRKKEHKGGKTMLPIRWMAPECINYG

IYSSKSDVWSFGVVMFEVFS-GEYPYADV----KVLKELRRKVAHENLRLKPPSD-------MPTDDAKVMEMCFEP-VDNRATFVQVCNRY
....|||||||||.|.|.|. |. || ..    .  .|....| . . . .||.|       .|..  ..|..| .   ..| || ... . 
KFTTKSDVWSFGVCMWEIFTYGQQPYPGMIQQMMSNQEVIEYVKQGYRMPQPPNDYPMSFVCCPDEMYQIMKQCWHEDPEDRPTFSEIHECF
Kinase F26E4.5.AA Pkinase_Tyr 195-433 39 4e-96 326.19 Pfam 1-252 (270) Show / Hide 
Range on Protein: 195-433
Range on HMM: 1-252/270
Sequence Identity: 39% (101 aa)

INLGKKLGNGEFGEVFQGVLSVGIFTNDVEVAVKTMKGSKVTADE--RITFLREANLMLKL-NHKYVVRLYGVAT-QQEP--IMIVMELCSGGCLKSRIE
| .||||| |.||||..|..      ....||||..|  . . ..  |  |.|||..| .| .|. .|||||| | |.||  |.||||.. .|.|..   
ITFGKKLGEGAFGEVYKGTWKGDPDNTKIPVAVKMLKE-GAMHEQNCREDFMREAKIMKQLGHHPNIVRLYGVCTDQGEPNQIYIVMEYMPHGDLLDYLR

KK---DEQLSDVLKRKYCKQIAKGMRYLEKKQVIHRDLAARNVLLDKSDNCKISDFGLSLFG----KL-HKEQKLMKVPIRWLAPETLLKGIYSSKSDVW
|.   ...|.   . ..| |||||| ||| |. |||||||||.|....  .||.||||.          .| .. . .||.|.||| .  |....|||||
KHREDKQPLTMKDLLQMCWQIAKGMEYLESKNCIHRDLAARNCLVTENNVVKICDFGLARDIYNDDYYYRKRGGGK-LPIKWMAPECINYGKFTTKSDVW

SFGVVMFEVFS-GEYP-YADVKVLKELRRKVAHENLRLKPPSDMPTDDAKVMEMC
||||.|.|.|. || | |...    |. .... .. |...| . | .  ..| .|
SFGVLMWEIFTYGEQPTYPGM-SNEEVYEYIYEDGYRMPCPENCPDEIYDLMKQC
Kinase F26E4.5.AA TK 195-450 22 3.3e-94 316.2 In-house 1-486 (486) Show / Hide 
Range on Protein: 195-450
Range on HMM: 1-486/486
Sequence Identity: 22% (109 aa)

INLGKKLGNGEFG---EVFQGVLSVGI---------------------FTNDVEVAVKTMK-GSKVTADERIT-----------FLREANLMLKLN----
| |||||| |.||   ||..| .  ..                       . ..||||..| |.  ...|..            ||.||. | ...    
ITLGKKLGEGQFGSFGEVYKGEWRGRNPWNGKRFPCHMTVTLKCKNGKEGGKTPVAVKMLKEGDAMSQEEFFDEEMHDRDGGEDFLEEAEEMKMMCHSLG

-HKYVVRLYGVATQQ------------EPIMIVMELCSGGC----LKSRIEKKDE---------------------------------------------
 |. .|||||| ||.            ||.|||||....|.    |..   |...                                             
HHPNIVRLYGVCTQGEPKPCFEVVVHQEPWMIVMEYMPHGDMDGSLRDYLRKCRPKFQHEQDCPDNQHNKYPPSKLHHCMKGDITYSHESNSPCPEEQDY

------------------------------QLSDVLKRKYCKQIAKGMRYLEKK------QVIHRDLAARNVLLDKSDN-----------CKISDFGLS-
                              ||.   .  .| |||.||.||..|      ...||||||||.|......           |||.||||| 
DDDLIKDHPPPLTTKDLLQMAWQWCLTCKHQLTMHQLL-MCWQIACGMEYLHSKNCEFIQNFVHRDLAARNCLVGENNVCKWHFDGCGPVCKIADFGLSR

-----LFGKLHKE-----------------------------QKLMKVPIRWLAPETLL---------KGIYSSKSDVWSFGVVMFEVFS-GEYPYADVK
     |  .....                             |. .|.||||.|||.|.         .|....|||||||||.|.|.|. |. ||.   
QGSGVLARDIYSDDDYYRKSSYGTGRPMWPFEDDPWQDYYRQQSGGKLPIRWMAPECLNDRVFSEAEKYGKFTTKSDVWSFGVLMWEIFTYGQEPYYGGM

VL---------KELRRKVAHE-------------NLRLKPPSDMP--------------TDDAKVMEMCFEP-VDNRATFVQVCNRY
           .|. ...  .              .|...| ..|              .. . .| .|...  . | || |. .. 
SNQDVWKDGDNQEVMEYLRRGGRLCRSGLNEVGYRMRMPQPPHCPDWMRYRMHPPHCPPEEYYDLMQQCWHYDPEDRPTFSQLHEQL
Kinase F26E4.5.AA UTK 195-450 30 2.1e-71 243.55 In-house 1-296 (296) Show / Hide 
Range on Protein: 195-450
Range on HMM: 1-296/296
Sequence Identity: 30% (91 aa)

INLGKKLGNGEFGEVFQGVL-SVGIFTNDVEVAVKTMKGSKVTADERI---TFLREAN---LMLKLN-HKYVVRLYGVATQQEPIMIVMELCSGGCLKS-
. ||..|| |.||||. . .  .     .. ||||. . .... .|.    .|..||.   .| ... | .|.||.|| ||.||.|||.|....| | | 
VQLGRQLGQGAFGEVHKARFTQCSEHMYEMDVAVKVCQHHADAQQEPEPYPDFMEEARELQMMKQFHWHPNVLRLVGVCTQEEPWMIVTEYMENGDLRSY

--RIEK----KDEQLSDVLKRKYCKQIAKGMRYLEKKQVIHRDLAARNVLLDKS-------DNCKISDFG---LSLFGK------------LHKEQKLMK
  |  .     ...|..  . ... .|| || ||. ....||||||||.|....         |||.|||   .|   .            . . |   .
LRRHRPTPPACPHWLTLHQRLCMAWDIARGMQYLHSCGFVHRDLAARNCLVHMHRMMWHCMMVCKIADFGRGGMSRRVNTFHFSNRYWESYYYMAQHQDR

VPIRWLAPETLLKG-IYSSKSDVWSFGVVMFEVFS-GEYPYAD---VKVLKELRRKVAHENLRLKPPSDMPTDDAKVMEMCFEP-VDNRATFVQVCNRY
.|||| ||| | ..  ...||||||||||..|... |  ||..   ..|.......     .|...| |.| .  ..|  | .. ...| .|...  . 
WPIRWMAPEALTHHTRFTTKSDVWSFGVVCWEIWTWGRLPYPGMSNMQVWHQVCNGGR---YRMPCPWDCPHPVYRLMHRCWHYDPQERPDFEDLVQQM
Kinase F26E4.5.AA Src 195-396 40 1.5e-64 218.19 In-house 1-201 (255) Show / Hide 
Range on Protein: 195-396
Range on HMM: 1-201/255
Sequence Identity: 40% (84 aa)

INLGKKLGNGEFGEVFQGVLSVGIFTNDVEVAVKTMKGSKVTADERITFLREANLMLKLNHKYVVRLYGVATQQEPIMIVMELCSGGCLKSRIE-KKDEQ
| | .|||.| ||||..|.     . . ..|||||.|      .    ||.||..| || |. .|.|| | .| ||| || |. | |.|      .....
IKLCRKLGQGQFGEVWMGY-----WNGNTKVAVKTLKPGTMSPEA---FLQEAQIMKKLRHEKLVQLYAVCSQEEPIYIVTEYMSHGSLLDYLKKDGEGR

LSDVLKR-KYCKQIAKGMRYLEKKQVIHRDLAARNVLLDKSDNCKISDFGLSLFGK----LHKEQKLMKVPIRWLAPETLLKGIYSSKSDVWSFGVVMFE
   . .      |.|.|| |||....||||||||||| ...  ||. ||||    |        ..  |.||.| ||| .. | .. ||||||||. . |
HLHLPQLIDMAAQVAEGMAYLESMNYIHRDLAARNVLVGENNVCKVADFGLARLIKEDDDEYCARHGAKFPIKWTAPEAINYGRFTIKSDVWSFGILLTE

VFS-GEYPY
... | .||
IVTYGRVPY
Kinase F26E4.5.AA Ack 195-397 41 1.5e-63 213.25 In-house 1-213 (266) Show / Hide 
Range on Protein: 195-397
Range on HMM: 1-213/266
Sequence Identity: 41% (89 aa)

INLGKKLGNGEFGEVFQGVLSVGIFTNDVEVAVKTMKGSKVTAD-ERITFLREANLMLKLNHKYVVRLYGVATQQEPIMIVMELCSGGCLKSRIEKKDEQ
| |..|||.|.|| | .|. .       ..||||  .  |.... .   ||||.. |..|.|  .||||||   |  .| |.||. .| |  .  | .  
ITLCEKLGDGCFGVVWRGEWTN-PGGKHIQVAVKCLRSDKMQQPNCMDDFLREVAIMHSLDHPHLVRLYGVVLDQPMLMMVTELAPCGSLLDCLRK-HCR

LSDV-LKR--KYCKQIAKGMRYLEKKQVIHRDLAARNVLLDKSD-NCKISDFGLS--LFGKLH----KEQKLMKVPIRWLAPETLLKGIYSSKSDVWSFG
 .   . .   .| |||.|||||| |  |||||||||.||   |   ||.||||.  | .       .... .|||. | ||| | ..  |..||||.||
TAFFLIHTLCDFCMQIAMGMRYLEMKRCIHRDLAARNILLFSDDRKVKICDFGLMRALGQNEDYYRMEFHRNLKVPFAWCAPECLRHRQFSHASDVWMFG

VVMFEVFS-GEYPYA
| . |.|| || |.|
VTLWEMFSYGEEPWA
Kinase F26E4.5.AA SFK-Src 195-389 42 7e-63 184.95 In-house 1-192 (259) Show / Hide 
Range on Protein: 195-389
Range on HMM: 1-192/259
Sequence Identity: 42% (84 aa)

INLGKKLGNGEFGEVFQGVLSVGIFTNDVEVAVKTMKGSKVTADERITFLREANLMLKLNHKYVVRLYGVATQQEPIMIVMELCSGGCLKSRIEK-KDEQ
| | |||| | ||.|..|.       |  ||||||.|   . |.|   ||.|| .| || |   ..|| | |  ||| |. ||.  | |       . . 
IRLEKKLGSGQFGDVWKGR-----WNNTTEVAVKTLKPGAMSAEE---FLQEAQVMKKLRHPNLIQLYAVCTDGEPIYIITELMKYGSLLDYLHEPHGRS

LSDVLKRKYCKQIAKGMRYLEKKQVIHRDLAARNVLLDKSDNCKISDFGLSLFGKLHKE----QKLMKVPIRWLAPETLLKGIYSSKSDVWSFGVVMFEV
|   .      |.| || ||| .  .||||||||||   .  ||. |||.|       |    ... | ||.| |||  .   .| ||||||||. | |.
LRMPQLVDMAAQVAHGMAYLEAQNFVHRDLAARNVLVGDNNVCKVGDFGMSRVLAQDDEGYTAHEGAKFPIKWTAPEAMNMNRFSIKSDVWSFGILMMEI
Kinase F26E4.5.AA TK-Unique 195-407 32 5.4e-62 212.26 In-house 1-254 (294) Show / Hide 
Range on Protein: 195-407
Range on HMM: 1-254/294
Sequence Identity: 32% (83 aa)

INLGKKLGNGEFGEVFQGVLSVGI--FTNDVEVAVKTMKGSKVTADERITFLREANLMLKLN-HKYVVRLYGVATQQ-EPIMIVMELCSGG----CLKSR
...|...| |.||.|. | .. ..  .  .. ||||. |  ..|  ..  ||.|...| .|  |...|...|. |   || ||.|| |..|    .|...
LEVGDVIGEGAFGQVWRGEVWGIWKHWDKQKCVAVKMLK-DNATDTDKQDFLKEIQMMKELGDHPNIVQCLGCCTKSDEPWMIIMEYCPCGNLQHYLRTC

IEK-----------------KDEQLSDVLK----RKYCKQIAKGMRYLEK--KQVIHRDLAARNVLLDKSDNCKISDFGLSL----FGKLHKEQKLMKVP
  .                 .|... . ..      ...|||.|| ||..  |...||||.||||||    .|||.|||..      |.. ....  ..|
RPAMRQHQTYGNLKFDFHHMPDKPRTEPISPKDLYHFAWQIACGMEYLASQRKKIVHRDLCARNVLLTEDKVCKICDFGMARDVYTNGVYSMMCSQGRIP

IRWLAPETLL--KGIY-SSKSDVWSFGVVMFEVFS-GEYPYADV---KVLKELRR
|||.||| |.  .|.| ..|||||||||.|.|.|. |..|| ..   ......|.
IRWMAPESLKCYHGMYHTTKSDVWSFGVLMWEIFTLGACPYPGMPWKDIMECIRD
Kinase F26E4.5.AA TKL 201-450 21 8e-60 205.06 In-house 1-364 (364) Show / Hide 
Range on Protein: 201-450
Range on HMM: 1-364/364
Sequence Identity: 21% (81 aa)

LGNGEFGEVFQGVLSV------GIFTNDVEVAVKTMKGSKVTADER-------------------------ITFLREANLMLKLNHKYVVRLYGVATQQE
.| | ||||..|..        .    . .||||..|   .  ...                          .. .|...|..|.|  .|...|.... .
IGSGGFGEVYKGKWRGWGGKCPS--DTGKDVAVKKFKSHNDDEFTKNSQENNDNNNYSDMQLNDPEASWFRFFEEEEIMMMSRLRHPNIVQFMGYCCCPP

P-------------IMIVMELCSGGC-LKSRIEKKDEQLSDVLKRKYCKQIAKGMRYLEK--------KQVIHRDLAARNVLLDKSDN------------
.             ..||||.|.||. |   .          .. . ...||.|| ||          ...|||||  .|.|.|.  .            
CGCVCMHPVGPWGQLCIVMEYCPGGSLLHYLH--------WHQRCRWALDIARGMNYLHSMNPKWCTKPPIIHRDLKSKNILVDENWTNVSNYMYNPNAD

--CKISDFGLSLFGKLHKE-------------------QKLMKV-PIRWLAPETLL----------------KGIYSSKSDVWSFGVVMFEVFSGEYPYA
  |||.||||| | . ...                   .. ...  .||.||| |                 .. || |.||.|||.|..|..... ||.
WCCKICDFGLSRFMSQSGNMNDTMTTMMESAEHQNNRKTTMTQCGTPRWMAPEVLRGQMNYTEKVGIDEFCKGFEYSEKCDVYSFGIVLWEILTRCRPYY

DVKVL--------KELRRKVAHENLRLKPP------------SDMPTDDAKVMEMCFEP-VDNRATFVQVCNRY
| .          .|   .|....||. .|            .|.|.. .| |..| ..  ..| .| ..  | 
DYPYMPMIFQDPFEEMFMMVCDKGLRPPIPPIWQNHHKMCPCPDCPPSMKKLMQDCWDHDPEKRPSFQEILKRL
Kinase F26E4.5.AA Eph 195-398 41 8.8e-58 192.63 In-house 1-213 (264) Show / Hide 
Range on Protein: 195-398
Range on HMM: 1-213/264
Sequence Identity: 41% (88 aa)

INLGKKLGNGEFGEVFQGVLSVGIFTNDV---EVAVKTMKGSKVTADERITFLREANLMLKLNHKYVVRLYGVATQQEPIMIVMELCSGGCLKSRIEKKD
| . | .| |||||| .| |.. . ...|    ||.|| | .  |. .|..||.|| .|   .|  ..|| || |...|.||| |    | | |   ..|
IKIEKVIGAGEFGEVCCGRLKLPSGKREVWVDPVAIKTLKAG-YTEKQRWDFLSEASIMGQFDHPNIIRLEGVVTKSRPVMIVTEYMENGSLDSFLRQHD

EQLSDVLKRKYCKQIAKGMRYLEKKQVIHRDLAARNVLLDKSDNCKISDFGLSLFGKLHK------EQKLMKVPIRWLAPETLLKGIYSSKSDVWSFGVV
.|.. .      . || ||.||     .||||||||.|...   ||.|||||| . .  .      . .  |.|||| |||..  ....| |||||.|.|
GQFTVIQLVGMLRGIASGMKYLSDMNYVHRDLAARNILVNSNLVCKVSDFGLSRVLEDDPSVEATYTTRGGKIPIRWTAPEAIAYRKFTSASDVWSYGIV

MFEVFS-GEYPYAD
| || | || || |
MWEVMSYGERPYWD
Kinase F26E4.5.AA S_TKc 195-451 24 2e-56 194.67 SMART 1-231 (231) Show / Hide 
Range on Protein: 195-451
Range on HMM: 1-231/231
Sequence Identity: 24% (66 aa)

INLGKKLGNGEFGEVFQGVLSVGIFTNDVEVAVKTMKGSKVTADERITFLREANLMLKLNHKYVVRLYGVATQQEPIMIVMELCSG--GCLKSRIEKKDE
  ...|.| | ||.|....        . .||.| .|         ....|| ... | .|...|.||.|    . . .|||.|.|  | |...|.|.  
YEILRKIGKGAFGKVYKCRHKK----TGRIVAIKIIK---------EHIRREIQILKK-HHPNIVKLYDVFQD-DHLYMVMEYCDGDLGDLFDYIKKRGR

Q-----LSDVLKRKYCKQIAKGMRYLEKKQVIHRDLAARNVLLDKSDNCKISDFGLSLFGKLHKEQKLMKVPIRWLAPETLLKGIYSS-KSDVWSFGVVM
.     ..    |.|..||.... |. ....|||||   |.|||.  . ||.||||. .       . . .   ..||| |    |.  |.|.||.|...
HGLRFPFPE-HARFYMYQICCALEYCHSHGIIHRDLKPENILLDE--HIKICDFGLARQL------TTFCGTPWYMAPEVL---GYGKCKCDWWSCGCIL

FEVFSGEYPYADVKVLKELRRKVAHENLRLKPPSDMPTDDAK-VMEMCFE-PVDNRATFVQVCN--------RYK
.| ..|. |.     .... .|.              ...||  .. |..   ..| |  .. .         . 
YEMLCGYPPFP---QMQMMFKKIG-------------SPEAKDFIRKCLQKDPEKRPTA-EALQDEWDIKCHPWF
Kinase F26E4.5.AA Pkinase 195-396 29 2.3e-44 157.95 Pfam 1-212 (293) Show / Hide 
Range on Protein: 195-396
Range on HMM: 1-212/293
Sequence Identity: 29% (65 aa)

INLGKKLGNGEFGEVFQGVLSVG-IFTNDVEVAVKTMKGSKVTADERITFLR--EANLMLKLNHKYVVRLYGVATQQEPIMIVMELCSGG----CLKSRI
. .|.|.| | ||.|....     .     .||||..| ..   ....| .|  |. .|..|||...||||.. .    | .|||.| ||     |...|
YHIGRKIGSGSFGCVYKCHHKGTGK-----IVAVKIIKKRHEKSWKDQTHRRLSEIQIMKRLNHPNIVRLYDWFEDKDHIYMVMEYCEGGLYVMDLFDYI

E-KKDEQL--SDVLKRKYCKQIAKGMRYLEKKQVIHRDLAARNVLLDKSDNC----KISDFGLSLFGKLHKEQKLMKVP---IRWLAPETLL-KGIYSSK
. ...  .  |.   ..|..||..|. |. .. .|||||   |.|.|. ...    ||.||||. . . .  .  |...   ....||| ..    |..|
STWRHGCFYFSEWECKFYMYQILRGLEYCHSMGIIHRDLKPENILIDNNGHIDACVKICDFGLAKQFD-Y-NNS-MTTFCGTPWYMAPEVIRGGQYYGPK

SDVWSFGVVMFEVFSGEYPY
.|.||.|....|...|. |.
VDMWSCGCILYEMLCGRPPF
Kinase F26E4.5.AA Syk 195-344 34 5.4e-44 149.33 In-house 1-153 (257) Show / Hide 
Range on Protein: 195-344
Range on HMM: 1-153/257
Sequence Identity: 34% (55 aa)

INLGKKLGNGEFGEVFQGVLSVG---IFTNDVEVAVKTMK---GSKVTADERITFLREANLMLKLNHKYVVRLYGVATQQEPIMIVMELCSGGCLKSRIE
..... .| |.|| | .|..           ..||.|. |   . .   .|   |.|||..| .| |...||. |.. . |. | |||. ..| .   . 
LVQDNEIGCGNFGSVHKGWYMMKSGAGEKQWIKVAIKMLKADHNQPADKQE---FMREAQVMCQLDHPCIVRMIGIC-HAEMMMMVMEMAELGPMHKYLQ

KKDEQLSD--VLKRKYCKQIAKGMRYLEKKQVIHRDLAARNVLLDKSDNCKISDFGLS
.. .  ..  ||.  .  |.| || ||| |. .|||||||||||      ||||||.|
QHRHEITANNVLELWHT-QVAMGMCYLEEKHFVHRDLAARNVLLVNRHYAKISDFGMS
Kinase F26E4.5.AA Syk 359-400 53 3.7e-15 48.6 In-house 172-214 (257) Show / Hide 
Range on Protein: 359-400
Range on HMM: 172-214/257
Sequence Identity: 53% (23 aa)

PIRWLAPETLLKGIYSSKSDVWSFGVVMFEVFS-GEYPYADVK
|..| |||   ... |.||||||||| | | || |  ||.  |
PVKWYAPECIYYYKFSHKSDVWSFGVTMWEMFSYGQKPYGEMK