F46G11.3

Species: Nematode worm
Alias: CE04586, F46G11.3, aSWK226
External Links: Wormbase Link ,
Annotation: WormBase Physical Map location: X: 5787170-5790173, WormBase Genetic Map location: X:-4.21,

Classification

Group: Other
Family: NAK
Subfamily: GAK

Sequence

Name Sequence Type Origin Length Description Download
F46G11.3.kin_dom Protein Kinase Domain Sugen global kinase HMM prediction 266 Kinase domain by global Sugen HMM Fasta, JSON
F46G11.3.AA Protein Genbank 570 None Fasta, JSON

Protein domain

Protein domains of F46G11.3.AA. The domains are annotated by HMM profiles from Pfam and SMART, as well as in-house data which includes HMMs of each individual kinase group, family and subfamily. Here is domain list in details, including sequence identity, significance and alignment. In particular, you can find can find the best hit kinase group/family/subfamily, which is helpful to understand the relationship between kinases.Kinase domain and best hit kinase group/family/subfamily are highlighted in red and blue. Visualized by pviz.

Usage: Zoom in selected region by dragging mouse and zoom out by double-clicking.

Domain Protein name Domain Name Range Identity (%) Significance Score Profile Source Profile Range (length) Alignment
Kinase F46G11.3.AA GAK 39-304 54 2.1e-216 725.19 In-house 1-277 (277) Show / Hide
Range on Protein: 39-304
Range on HMM: 1-277/277
Sequence Identity: 54% (151 aa)

YRVEKVIAKGGFGTVFLATNTK-GKQVAVKIMLSHDAAATKDIDNEIDMMKKLQ-HENIIQLFDASAESRS-SNRSVKEYKISMEYCKFSIADVLLK---
|||..|||.|||..|..|.... |...|.|.|||||..|...|.|||.|||||| ||||.|..|||..||. ||.|..||...|||||||.....||   
YRVRCVIAEGGFAFVYVAQDVQTGREYALKRMLSHDMQANRAIINEICMMKKLQGHENIVQFCDASYISREESNQSQAEYLLLMEYCKFSQLVDCLKRME

-YKEVSIDFVVRIIYFTTRALVYLHSVG--AIHRDIKAENLLINGNGKLKLCDFGSATTKSIEMAP-LSNSERLAVQEEMFKYTTPITRSPEVCDVYSNW
 ||..|.|.|.||.|...||....||..  .||||||.||.||......||||||||||||..... .|...|..|..|||..|||..||||.||.||||
CYKPFSCDCVLRIFYQMCRAVQHMHSQKPPIIHRDIKIENFLIGNQKTIKLCDFGSATTKSHYPDYSWSAQKRSMVEDEMFRHTTPMYRSPEMCDLYSNW

PIGKQQDNWAMGCLIYFVAFGEHPF-DGSALAIINGKYKKPPPVQQNQLSAFADLIAKCLTPNPDERITAAKIEEYM
|||..||.|||||..||.....||| ||..|.||||.|.||.|.|.||...|.|||..||..|||||...|...|||
PIGHKQDIWAMGCMLYFMCYRQHPFEDGAKLRIINGNYMKPIPPQDNQYMCFHDLIRACLQVNPDERLDIAMVVEYM

Kinase F46G11.3.AA NAK 39-304 35 1e-131 442.03 In-house 1-299 (299) Show / Hide
Range on Protein: 39-304
Range on HMM: 1-299/299
Sequence Identity: 35% (105 aa)

YRVEKVIAKGGFGTVFLAT----------NTKGKQVAVKIMLSH-DAAATKDIDNEIDMMKKLQ-HENIIQLFDASAESRS-SNRSVKEYKISMEYCKFS
|.|||..|.|||..|.|..          |..|...|.| |..| |. .......||.|||||| |.||.|..|.....|. ||...... . ...|..|
YTVEKYLAEGGFSYVYLVQDNYINHPDNPNSNGEKYALKRMICHSDEQDLNACKREIEMMKKLQHHNNIVQYIDSHINERDDSNGTWEVFLLMEYCCHGS

IADVLLK-----YKEVSIDFVVRIIYFTTRALVYLH----SVGAIHRDIKAENLLIN---GNGKLKLCDFGSATTKSIEMAP-LSNSERLAVQEEMFKYT
..|...|     ..... |....|........ ..|    ... |||||| ||.|..    .|..|||||||.||..|..    ....|..||....|||
LWDLMNKRLMDKGTCFTEDEILQIFCDVCEGVQAMHQCQPPKPIIHRDIKIENILLSESHHDGNYKLCDFGSMTTAIIQPENRWEAQYRSMVQDWINKYT

TPITRSPEVCDVYSNWPIGKQQDNWAMGCLIYFVAFGEHPFD-------GSALAIINGKYKKPPPVQQNQLSAFADLIAKCLTPNPDERITAAKIEEYM
||. |.|| ||.|||.||....|.||.||..|. .|..|||.       .|.|||.||.||...|..... ... ||| ..|||.|..|.. ... ...
TPMYRAPEMCDLYSNCPIDEKVDIWALGCMLYKMCFYTHPFEDCYQRHDSSKLAIQNGNYKYSIPDNSRYSQQMHDLIRYMLTPDPEQRPNIYQVLNQL

Kinase F46G11.3.AA S_TKc 39-304 25 2.9e-54 187.52 SMART 1-231 (231) Show / Hide
Range on Protein: 39-304
Range on HMM: 1-231/231
Sequence Identity: 25% (74 aa)

YRVEKVIAKGGFGTVFLATNTK-GKQVAVKIMLSHDAAATKDIDNEIDMMKKLQHENIIQLFDASAESRSSNRSVKEYKISMEYCKF---SIADVLLKYK
|.. ..| ||.||.|......| |..||.||.        ..| .||...|| .|.||..|.|.  .        ... . ||||     .  |.. |..
YEILRKIGKGAFGKVYKCRHKKTGRIVAIKIIK-------EHIRREIQILKK-HHPNIVKLYDVFQD--------DHLYMVMEYCDGDLGDLFDYIKKRG

E------VSIDFVVRIIYFTTRALVYLHSVGAIHRDIKAENLLINGNGKLKLCDFGSATTKSIEMAPLSNSERLAVQEEMFKYTTPITRSPEVCDVYSNW
        .   . ...| . .|| |.|| | ||||.| ||.|..    .|.||||.|.                    .    ||  ..|||.      
RHGLRFPFPE-HARFYMYQICCALEYCHSHGIIHRDLKPENILLDE--HIKICDFGLARQL------------------TTFCGTPWYMAPEVL------

PIGK-QQDNWAMGCLIYFVAFGEHPFDGSALAIINGKYKKPPPVQQNQLSAFADLIAKCLTPNPDERITAAKIEE---------YM
. ||   | |. ||..|  . |. ||.    ....              . . |.| |||. .|..|.|| .. .         ..
GYGKCKCDWWSCGCILYEMLCGYPPFP-QMQMMFKKIG----------SPEAKDFIRKCLQKDPEKRPTA-EALQDEWDIKCHPWF

Kinase F46G11.3.AA Pkinase 39-304 25 9.3e-51 179.74 Pfam 1-293 (293) Show / Hide
Range on Protein: 39-304
Range on HMM: 1-293/293
Sequence Identity: 25% (81 aa)

YRVEKVIAKGGFGTVFLATNTKGKQ-VAVKIMLSHDAAATKDIDN----EIDMMKKLQHENIIQLFDASAESRSSNRSVKEYKIS--MEYCKF-----SI
|.....| .|.||.|..... .  . |||||.  ...   ||. .    || .||.|.|.||..|.|.  .         . .|   ||||       . 
YHIGRKIGSGSFGCVYKCHHKGTGKIVAVKIIKKRHEKSWKDQTHRRLSEIQIMKRLNHPNIVRLYDWFED---------KDHIYMVMEYCEGGLYVMDL

ADVLL--KYKEV--SIDFVVRIIYFTTRALVYLHSVGAIHRDIKAENLLINGNGKL----KLCDFGSATTKSIEMAPLSNSERLAVQEEMFKYT-TPITR
.|..   ... .  | . . ...| . |.| |.|| | ||||.| ||.||. || .    |.||||.|  ..           .  .. |  .. ||  .
FDYISTWRHGCFYFSEWECKFYMYQILRGLEYCHSMGIIHRDLKPENILIDNNGHIDACVKICDFGLAKQFD-----------Y-NNS-MTTFCGTPWYM

SPEVCDVYSNWPIGKQQDNWAMGCLIYFVAFGEHPFDGS-------ALAIINGKYKKPPPVQQNQL---------------------SAFADLIAKCLTP
.|||.   .. ..|.  | |..||..| ...|. ||.|.        ...|. . ..|.. .  ..                     ... |.| .||..
APEVIR--GGQYYGPKVDMWSCGCILYEMLCGRPPFPGHCWHDNHDQMQMICRIMGPPLHFDWPWWCSISYFFFRHWHFHWTFHNWSEECKDFIKWCLCK

NPDERITAAKIEEY--M
.| .|.||. | .   .
DPKKRPTAEQILQHPWF

Kinase F46G11.3.AA BIKE 41-268 33 5.5e-39 135.83 In-house 3-234 (267) Show / Hide
Range on Protein: 41-268
Range on HMM: 3-234/267
Sequence Identity: 33% (79 aa)

VEKVIAKGGFGTVFLATNTKGKQVAVKIMLSHDAAATKDIDNEIDMMKKLQ-HENIIQLFDASAESRSSNRSVKEYKISMEYCKFSIADVLLKYKEVS--
||...| ||| .|||. . || . | | |        .    |. .||..  | ||.   |..  . .    | |  | ||||.  . ... .  ..   
VEEQLAEGGFAMVFLVRDHKGNKCALKRMYVNNEHDLNVCCREHQIMKQCSGHKNIVGYVDCYINCIG--NGVWECMILMEYCRHQVVNMMNQRLQQGQY

--IDFVVRIIYFTTRALVYLHSVGA--IHRDIKAENLLINGNG--KLKLCDFGSATTKSIEMAPLSNSERLAVQEEMFKYTTPITRSPEVCDVYSNWPIG
   . | .|   .  |  .||      |||| | || |.. .|     ||||||||.|  .    .     .|..|  ||||   |.||  | ||  .|.
FTEQEVLQIFCDVCEAVSRLHHCQTPIIHRDLKVENILLHDHGPPHYVLCDFGSATNKFLNPQKHGVN---YVKDEIEKYTTMCYRAPEMIDLYSGKEIT

KQQDNWAMGCLIYFVAFGEHPFDGSALAIINGKYKKP
   | ||.||. |   |   ||. | ||| .|... |
TKADIWALGCMLYKLCFFCLPFGESQLAICDGNFTIP

Kinase F46G11.3.AA Ciliate-E2 39-300 20 8.2e-34 113.44 In-house 1-359 (365) Show / Hide
Range on Protein: 39-300
Range on HMM: 1-359/365
Sequence Identity: 20% (77 aa)

YRVEKVIAKGGFGTVFLATN------------------------TKGKQVAVKIMLSHDAAATKDIDNEID-------------MMKKLQHENIIQLFDA
| . |.| .|.||.|.....                        .|.|..|.|||   .  ..| .....              ....|.| |||.....
YKFIKKIGQGNFGSVYKCKVWKVQKQFAIKIIDQKQQRQQMQEKVKIKIYAMKIMKKNQIEQIKQEIHIMREINCFYKKINEKNILEQLNHPNIIKMYEC

SAE-SRSSNRSVKEYKISMEYCKF-SIADVL----LKYKEV-------SIDFVVRIIYFTTR---------------ALVYLHSVG-AIHRDIKAENLLI
  | ....      . . ||||.  .  | .    .| ..        ..  . .|..  ..               || |||| .  |||||| ||.|.
FQEKDDNN------IYLVMEYCQGGDLFDYIKNNKKKRNHEIEKDKYFTEKEIKYIMKQILQGFKTKAEFYIACIILALEYLHSKNNIIHRDIKPENILF

NGNGKLKLCDFGSATTKSIE-------------------------MAPLSNSERLAVQEEMF--KYTTPITRSPEVCDVYS------NWPIGKQQDNWAM
     .|..||| ..  ...                         |.       . .|..||   . ||   .||.    .        . ... | |..
-----IKIIDFGLSKKYDDDNQNRTHKQQCKWYMFKNDTSRTPGYMD-------QIIQQNMFNTICGTPGYMAPEILNGKKYDNQQKQKGYDYKCDIWSL

GCLIYFVAFGEHPFDGSALAIINGKYKKPPPV-------------QQNQLSAF-ADLIAK----CLTPNPDERIT-AAKI
|...|.  ||..||      |...|.. |.|                ...|    ||| |    .|  .|..||| . .|
GVILYEMLFGKPPF---QQQIKQCKIDFPCPEWQKDTQCIQCKWKSWKKWSQECKDLIKKFGKRMLQKDPEKRITGWEQI

Kinase F46G11.3.AA TKL 45-304 18 4.4e-33 116.23 In-house 1-364 (364) Show / Hide
Range on Protein: 45-304
Range on HMM: 1-364/364
Sequence Identity: 18% (67 aa)

IAKGGFGTVFLATNTK---------GKQVAVKIMLSHDAA---------------------------ATKDIDNEIDMMKKLQHENIIQLFDASAESRSS
| .||||.|. ..            || ||||.. ||.                             . . . .|| ||..|.|.||.|.  .. .... 
IGSGGFGEVYKGKWRGWGGKCPSDTGKDVAVKKFKSHNDDEFTKNSQENNDNNNYSDMQLNDPEASWFRFFEEEEIMMMSRLRHPNIVQFMGYCCCPPCG

N------RSVKEYKISMEYCKFSI-ADVLLKYKEVSIDFVVRIIYFTTRALVYLHS--------VGAIHRDIKAENLLINGNGK--------------LK
        . ... | ||||.     ..|.      ..  .|... . |.. ||||         . ||||.| .|.|.. |..              .|
CVCMHPVGPWGQLCIVMEYCPGGSLLHYLH------WHQRCRWALDIARGMNYLHSMNPKWCTKPPIIHRDLKSKNILVDENWTNVSNYMYNPNADWCCK

LCDFGSATTKS--IEMAPLSNSER------LAVQEEMFKYTTPITRSPEVCD---VYSNW----------PIGKQQDNWAMGCLIYFVAFGEHPFDGSAL
.|||| ....|   .|   .....      .  .  | .  ||   .||| .    |...          .  .. | ...| ... .. ...|...   
ICDFGLSRFMSQSGNMNDTMTTMMESAEHQNNRKTTMTQCGTPRWMAPEVLRGQMNYTEKVGIDEFCKGFEYSEKCDVYSFGIVLWEILTRCRPYYDYPY

A------------IINGKYKKPPPVQ------------QNQLSAFADLIAKCLTPNPDERITAAKIEEYM
             ..... ...||.              . .  ...|. .|  ..|..| .. .| ...
MPMIFQDPFEEMFMMVCDKGLRPPIPPIWQNHHKMCPCPDCPPSMKKLMQDCWDHDPEKRPSFQEILKRL

Kinase F46G11.3.AA CAMK 44-187 18 1.1e-32 102.1 In-house 1-244 (425) Show / Hide
Range on Protein: 44-187
Range on HMM: 1-244/425
Sequence Identity: 18% (46 aa)

VIAKGGFGTVFLATNT-KG------------KQVAVKIMLSH----------------------------DAAATKDIDNEIDMMKKLQ-------HENI
.. .|.||.|.|....  .            ..||.||.                               ..   | . .||..|||||       |.||
TLGRGSFGKVKLCIHKNTTGKERVHHIYTNGQKVAIKIIDKKKLKDKQNQDYSNCYKIDKSKCKHRYCWRRPKDRKNVRREIEIMKKLQGIGNKLDHPNI

IQLFDASAESRS--------SNRS-----VKEYKISM---EYCK-----FSIADVLLKYKE---------------VSIDFVVRIIYFTTRALVYLHSVG
|.|...   ..         . .       |.. . |   |||      . . | . . .                .. . . |..     |. |.|| .
IKLYEVYEDPHYFKNTNDYET-SKQVFTKDKHMYMVMEIMEYCSGGELFDDLFDYIVEHGCYGEEFDQFDIVERGRFTEREARRYFRQICSAVHYCHSHN

AIHRDIKAENLLINGN-----------------GKLKLCDFGSAT
 .|||.| ||.|.. |                 ...|..||| |.
IVHRDLKPENILLDDNNDDSDPVEHDEIFDWNNNNIKIIDFGFAN

Kinase F46G11.3.AA STE 39-187 25 1e-29 102.16 In-house 1-195 (359) Show / Hide
Range on Protein: 39-187
Range on HMM: 1-195/359
Sequence Identity: 25% (50 aa)

YRVEKVIAKGGFGTVFLATNTK----------------GKQVAVKIMLSHDA-----------------AATKDIDNEIDMMKKLQ--HENIIQLFDASA
..  ..| ||.||||..| | |                |. .|.|.|   .                     ..| .||..|||..  |.||.. ...  
WEGIEKIGKGAFGTVYKAMNHKNCNIHKTGEVENNGETGEIMAIKQMNLENCNNKDENQENQELENKNHEEMQQILKEIKIMKKCNHMHPNIVKYYGCYF

ESRSSNRSVKEYKISMEYCKFSIADVLLK-YKEVSI--------------DFVVRIIYFTTRA-LVYLHSVGAIHRDIKAENLLINGNGKLKLCDFGSAT
     . .  |  | |||.    .| ..| ....                . . .|.. . .. | |||| . ||||||. | |.      |||||| ..
KEGHNHKNDDELWICMEYMDGGSLDDIIKHKYGCGKPLNHNRQHQHRFPESQIAYICRQILKGLLYYLHSHHIIHRDIKPANILL-----VKLCDFGVCG





Kinase F46G11.3.AA NAK-Unclassified 161-294 25 2e-25 85.58 In-house 196-393 (405) Show / Hide
Range on Protein: 161-294
Range on HMM: 196-393/405
Sequence Identity: 25% (52 aa)

IHRDIKAENLLIN----------------------------------------------------------GNGKLKLCDFGSATTKSIEMAPLSNSERL
|||||| || |.                                                            ||  |||||||...  | .      |..
IHRDIKIENVLFCNLRRPSNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNSEDSEHNGIYKLCDFGSCCECIITIE--NRQEMQ

AVQEEMFKYTTPITRSPEVCDVYSNWPIGKQQDNWAMGCLIYFVAFGEHPFD-GSALA-------IIN--GKYKKPPPVQQNQLSAFADLIAKCLTPNPD
 .|..  ..|||  |.||  | |.. ||    | || ||. |  .|.  ||. .  |.       |..  |||.  .|.. |  . .  || ..| ..|.
YLQDWINMHTTPQYRAPEMIDLYRCCPIDEKIDIWALGCFLYKMCFYTTPFEMCGQLHNASVTYKILHGLGKYE--FPSNHNYSNQLHNLIKIMLNEDPI

ER
.|
QR

Kinase F46G11.3.AA CAMKL 39-100 35 1.5e-21 65.41 In-house 1-82 (297) Show / Hide
Range on Protein: 39-100
Range on HMM: 1-82/297
Sequence Identity: 35% (29 aa)

YRVEKVIAKGGFGTVFLATN-TK-GKQVAVKIML----SHDAAATKD-----------IDNEIDMMKKLQ---HENIIQLFD
||..|.. ||.||.| |||.    |..||.||.     . |  ..|            |  ||  ||.|.   |.|||.|..
YRIGKTLGKGSFGKVKLATHIRTTGEKVAIKIIDKKKIWNDPWMKKNKCGQKHESDMRIRREIQIMKMLNIGKHPNIIKLYE

Kinase F46G11.3.AA MARK 39-101 38 6.7e-20 61.88 In-house 1-67 (262) Show / Hide
Range on Protein: 39-101
Range on HMM: 1-67/262
Sequence Identity: 38% (26 aa)

YRVEKVIAKGGFGTVFLATNTK-GKQVAVKIML---SHDAAATKDIDNEIDMMKKLQHENIIQLFDA
|.. |.| .|....| ||.... |..||.||.      |  . | .  ||. ||||.|.|||.||..
YKMLKTIGHGSYAKVKLACHKHTGRKVAIKIYEKFKLNDPQWMKNVMREIEIMKKLDHPNIIKLFHV

Kinase F46G11.3.AA CAMKL 151-187 48 1.3e-15 46.13 In-house 139-177 (297) Show / Hide
Range on Protein: 151-187
Range on HMM: 139-177/297
Sequence Identity: 48% (19 aa)

ALVYLHSVGAIHRDIKAENLLINGNG--KLKLCDFGSAT
|. |.|| | .|||||.||.|.  ||  ..|..||| ..
AVNYCHSHGIVHRDIKPENILLDENGNNNIKIIDFGFSN

Kinase F46G11.3.AA MARK 151-184 52 5e-15 45.73 In-house 116-151 (262) Show / Hide
Range on Protein: 151-184
Range on HMM: 116-151/262
Sequence Identity: 52% (19 aa)

ALVYLHSVGAIHRDIKAENLLINGNG--KLKLCDFG
|. |.|| . .|||||.||.||  ||  . |..|||
AVNYCHSKNIVHRDIKPENILIDENGNHNIKIIDFG

Kinase F46G11.3.AA TyrKc 39-304 19 5.4e-14 3.55 SMART 1-280 (280) Show / Hide
Range on Protein: 39-304
Range on HMM: 1-280/280
Sequence Identity: 19% (61 aa)

YRVEKVIAKGGFGTVFLATNTKGKQVAVKIMLSHDAAATKDIDNEIDMMKKL--QHENIIQLFDASAES--RSSNRSVKEYKISMEYCKF-SIADVLLKY
 . .|..  | ||.|...| .   ||||| . ..     .|. .|. .|.||  .|.||..|. .  ..  .    ... . | |||..  .  | | |.
ITLGKKLGEGAFGEVYKGTWK--IQVAVKMLKEDA---REDFMREARIMCKLGGHHPNIVRLYGVCTQQGRN--FMYIEPLMIVMEYMPHGDLKDYLRKH

KE-VSIDFVVRIIYFTTRALVYLHSVGAIHRDIKAENLLINGNGKLKLCDFGSATTKSIEMAPLSNSERLAVQEEMF-------KYTTP----ITR----
.. .. .  . . .   .   |||| . ||||. | | |.. |.  | .|||                 |.   .         .| ..     ..    
RPKLCMKDLLSFCWQIACGMEYLHSKNCIHRDLAARNCLVGENHTVKISDFG-----------------LSRDIYDDDQQGESKDYYRKKEHKGGKTMLP

----SPEVCDVYSNWPIGKQQDN--------WAMGCLIY-FVAFGEHPFDG---------SALAIINGKYKKPPPVQQN------QLSAFADLIAKCLTP
    .||.            ...        |. | ...    .|. |  |          ... .   |  |.|            ..  ... .|   
IRWMAPECI-----------NYGKFTTKSDVWSFGVCMWEIFTYGQQPYPGMIQQMMSNQEVIEYVKQGYRMPQPPNDYPMSFVCCPDEMYQIMKQCWHE

NPDERITAAKIEEYM
.|..| | . | |..
DPEDRPTFSEIHECF

Kinase F46G11.3.AA CAMK 229-302 22 9.9e-14 39.91 In-house 310-421 (425) Show / Hide
Range on Protein: 229-302
Range on HMM: 310-421/425
Sequence Identity: 22% (25 aa)

PIGKQQDNWAMGCLIYFVAFGEHPFDGSAL------------------AIINGKYKKPPPV--------------------QQNQLSA-FADLIAKCLTP
..|.. | |..|.. |.   |. ||.|.                     |..|||  |||                     .. ..|.   ||| |.|..
YYGPKCDMWSCGVILYIMLCGYPPFYGDCDNEICEDEWIGMNDYELFEKIMKGKYDFPPPYFSPISCNYGPEWWDDISDEFHH-FVSQECKDLIRKMLQV

NPDERITAAKIEE
.|..|.|.. . .
DPEKRMTIEQCLN

Kinase F46G11.3.AA NAK-Unclassified 39-123 25 2.1e-13 42.93 In-house 1-101 (405) Show / Hide
Range on Protein: 39-123
Range on HMM: 1-101/405
Sequence Identity: 25% (26 aa)

YRVEKVIAKGGFGTVFLAT---------------NTKGKQVAVKIMLSHDAAATKDIDNEIDMMKKLQ-HENIIQLFDASAE-SRSSNRSVKEYKISMEY
|.. . .| |||. |.|.                .  ..  . | |.  |    .   .||| ||... |.||....| ..  .. .|.| .|. . |||
YTIVRYLAEGGFSFVYLVKFSKYINPPDNTASVPHSNSNMYCLKRMICQDEESLNTMKREIDVMKRFRNHPNIVKYIDHHIMRENHNNQS-YEVFMLMEY

CK
|.
CS

Kinase F46G11.3.AA Pkinase_Tyr 39-98 27 8.8e-10 33.75 Pfam 1-69 (270) Show / Hide
Range on Protein: 39-98
Range on HMM: 1-69/270
Sequence Identity: 27% (19 aa)

YRVEKVIAKGGFGTVFLATNT-----KGKQVAVKIMLSHDAAA---TKDIDNEIDMMKKL-QHENIIQL
 .  |.. .| ||.|...| .     .. .||||..  .        .|  .|. .||.| .|.||..|
ITFGKKLGEGAFGEVYKGTWKGDPDNTKIPVAVKMLKEGAMHEQNCREDFMREAKIMKQLGHHPNIVRL

Kinase F46G11.3.AA STE 237-299 22 7.4e-08 23.96 In-house 252-350 (359) Show / Hide
Range on Protein: 237-299
Range on HMM: 252-350/359
Sequence Identity: 22% (22 aa)

WAMGCLIYFVAFGEHPF-DGSAL----AII--NGKY----------KKPPPVQQNQL-------------------SAFADLIAKCLTPNPDERITAAK
|  ||.|   | |..|. |.. .    .|.  ....          ..||| ...                     . | | |.|||. .|..| || .
WSLGCTIIEMATGKPPWHDMHPMRAMFMIPFNYHMQQQFEQLCIVNGPPPPLPDHLSQNEMISYGGSGTTYPHKWSPEFKDFINKCLQKDPNKRPTASQ

Kinase F46G11.3.AA CAMKL 231-302 28 3.1e-07 18.99 In-house 214-293 (297) Show / Hide
Range on Protein: 231-302
Range on HMM: 214-293/297
Sequence Identity: 28% (24 aa)

GKQQDNWAMGCLIYFVAFGEHPFDGS------------ALAIINGKYKKPPPVQQNQLSAFADLIAKCLTPNPDERITAAKIEE
|.. | |..| . |.  .|. |||.              . |. | |. |...   ..|   ||| | |..||..|.|.  |..
GPKVDIWSCGVILYAMVCGYLPFDDDTYNKQGKDNIYLYWKIMCG-YYPPIWY---HVSDCRDLIRKMLQVNPEKRPTIHQIMN

Kinase F46G11.3.AA MARK 235-302 34 9e-06 15.09 In-house 188-258 (262) Show / Hide
Range on Protein: 235-302
Range on HMM: 188-258/262
Sequence Identity: 34% (26 aa)

DNWAMGCLIYFVAFGEHPFDGSA-----L--AIINGKYKKPPPVQQNQL-SAFADLIAKCLTPNPDERITAAKIEE
| |..| . ||   |  ||||.      |   | .|||. |.      .     .|| . ||.||.||.|.  |..
DIWSLGVVLYFMVCGYFPFDGDTQDYKELYKKILRGKYDIPCH-----VSKECRNLIQRLLTVNPEERPTIEEIMK

Kinase F46G11.3.AA Pkinase_Tyr 150-184 45 0.001066 13.15 Pfam 122-156 (270) Show / Hide
Range on Protein: 150-184
Range on HMM: 122-156/270
Sequence Identity: 45% (16 aa)

RALVYLHSVGAIHRDIKAENLLINGNGKLKLCDFG
... ||.| . ||||. | | |.. |.. | ||||
KGMEYLESKNCIHRDLAARNCLVTENNVVKICDFG

Kinase F46G11.3.AA Pkinase_Tyr 281-304 33 1.32485 2.67 Pfam 247-270 (270) Show / Hide
Range on Protein: 281-304
Range on HMM: 247-270/270
Sequence Identity: 33% (8 aa)

DLIAKCLTPNPDERITAAKIEEYM
||. .|  ..|..| | . | | .
DLMKQCWHYDPEDRPTFSEIHEQL