odr-1

Species: Nematode worm
Alias: CE27430, aSWK276, R01E6.1, odr-1
External Links: Wormbase Link ,
Annotation: WormBase Physical Map location: X: 13549013-13554452, WormBase Genetic Map location: X:12.7029,

Classification

Group: RGC
Family: RGC

Sequence

Name Sequence Type Origin Length Description Download
odr-1.kin_dom Protein Kinase Domain Sugen global kinase HMM prediction 270 Kinase domain by global Sugen HMM Fasta, JSON
odr-1.AA Protein Genbank 1014 None Fasta, JSON

Protein domain

Protein domains of odr-1.AA. The domains are annotated by HMM profiles from Pfam and SMART, as well as in-house data which includes HMMs of each individual kinase group, family and subfamily. Here is domain list in details, including sequence identity, significance and alignment. In particular, you can find can find the best hit kinase group/family/subfamily, which is helpful to understand the relationship between kinases.Kinase domain and best hit kinase group/family/subfamily are highlighted in red and blue. Visualized by pviz.

Usage: Zoom in selected region by dragging mouse and zoom out by double-clicking.

Domain Protein name Domain Name Range Identity (%) Significance Score Profile Source Profile Range (length) Alignment
Kinase odr-1.AA RGC 493-754 27 3.4e-104 352.45 In-house 1-300 (300) Show / Hide
Range on Protein: 493-754
Range on HMM: 1-300/300
Sequence Identity: 27% (82 aa)

T-QRAEYVQFKQI---RKINFPETTLDYLYSLKQLQHDNLAKFYGIQVNDDIM----TMTILHTLVERGTLEEFCLDRDFGMDDTFKSAFMRDILKGLQY
. ... . ...|.   |...|...... |. ..|||||||.||.|........    .|.|.. . .||.|.... ..|..||..||..|.|||.||.||
EGDWVWIKKHNQRNLFRHWDFTRSMMRELKQMRQLQHDNLNKFIGMCIDPPMEYHPGNMCIVWEYCSRGSLQDILENDDIKMDWMFKYSFIRDIVKGMQY

LHKSSIGYHGHLQASTCLIDINWVLKLTLYGVSNFMSDQLDAENIKV---------PEQAAHMITYPQYVCFPPEHIREYDDSGKQP--PRVVRGSPKGD
||.|.|.|||.|  ..|..| .||.|.| .|..|.. .......|..          .|  ....|... ...|||.||.. .....  ....||..|||
LHHSPIRYHGNLKSWNCVVDSRWVVKITDFGLNNPLCHWFKHGQINPPCKSDDKSWQRQHDEHPYYKKMLWTAPEHLREWRMPHQWGPHRQTQRGTQKGD

IYCVGMIFYMMVEREDPYHLIHSVERP--NATLIKQILNEN-----------HMPRITDDYR-----QENMLLEMCKECWDRNPDKRPT-IKKLIESIST
.|..|.|.|... |. |..|.. ...|  ...  ..|. |.           ..| | .|       . . ||.....||...|..||. .... . ..|
VYSFGIIMYEIITRKGPWDLEPFCMWPGEYELSPMEIIEEVKYPPKKGGQKPFRPSIHEDEEGHMIECNPCLLHLMRDCWAEDPEERPDMFDQIRKQLKT





Kinase odr-1.AA RGC 493-754 27 3.4e-104 352.45 In-house 1-300 (300) Show / Hide
Range on Protein: 493-754
Range on HMM: 1-300/300
Sequence Identity: 27% (82 aa)

T-QRAEYVQFKQI---RKINFPETTLDYLYSLKQLQHDNLAKFYGIQVNDDIM----TMTILHTLVERGTLEEFCLDRDFGMDDTFKSAFMRDILKGLQY
. ... . ...|.   |...|...... |. ..|||||||.||.|........    .|.|.. . .||.|.... ..|..||..||..|.|||.||.||
EGDWVWIKKHNQRNLFRHWDFTRSMMRELKQMRQLQHDNLNKFIGMCIDPPMEYHPGNMCIVWEYCSRGSLQDILENDDIKMDWMFKYSFIRDIVKGMQY

LHKSSIGYHGHLQASTCLIDINWVLKLTLYGVSNFMSDQLDAENIKV---------PEQAAHMITYPQYVCFPPEHIREYDDSGKQP--PRVVRGSPKGD
||.|.|.|||.|  ..|..| .||.|.| .|..|.. .......|..          .|  ....|... ...|||.||.. .....  ....||..|||
LHHSPIRYHGNLKSWNCVVDSRWVVKITDFGLNNPLCHWFKHGQINPPCKSDDKSWQRQHDEHPYYKKMLWTAPEHLREWRMPHQWGPHRQTQRGTQKGD

IYCVGMIFYMMVEREDPYHLIHSVERP--NATLIKQILNEN-----------HMPRITDDYR-----QENMLLEMCKECWDRNPDKRPT-IKKLIESIST
.|..|.|.|... |. |..|.. ...|  ...  ..|. |.           ..| | .|       . . ||.....||...|..||. .... . ..|
VYSFGIIMYEIITRKGPWDLEPFCMWPGEYELSPMEIIEEVKYPPKKGGQKPFRPSIHEDEEGHMIECNPCLLHLMRDCWAEDPEERPDMFDQIRKQLKT





Kinase odr-1.AA TKL 519-752 15 8.3e-17 57.05 In-house 78-364 (364) Show / Hide
Range on Protein: 519-752
Range on HMM: 78-364/364
Sequence Identity: 15% (47 aa)

SLKQLQHDNLAKFYG--IQVNDD-IMT--------MTILHTLVERGTLEEFCLDRDFGMDDTFKSAFMRDILKGLQYLHKSSI-------GYHGHLQAST
....|.|.|. .|.|  .. ... ..         . |   ....|.|... .     .. ...  ...|| .|..||| .           |  |  . 
MMSRLRHPNIVQFMGYCCCPPCGCVCMHPVGPWGQLCIVMEYCPGGSLLHYLH-----WHQRCR--WALDIARGMNYLHSMNPKWCTKPPIIHRDLKSKN

CLIDINWV--------------LKLTLYGVSNFMSDQLD-------------------AENIKV-------PEQAAHMITYPQYVCFPPEHIREYDDSGK
.|.| ||               .|.. .| | |||   .                   . . ..       ||    .. |...|               
ILVDENWTNVSNYMYNPNADWCCKICDFGLSRFMSQSGNMNDTMTTMMESAEHQNNRKTTMTQCGTPRWMAPEVLRGQMNYTEKVGI-------------

QPPR--VVRGSPKGDIYCVGMIFYMMVEREDPYH-LIHSVERPN---ATLIKQILNENHMPRITDDYRQ-------ENM---LLEMCKECWDRNPDKRPT
 . .      |.| |.|  |.... .. |. ||. . .. . ..      .... .... | | .  ..       ...   . . ...||| .|.|||.
DE-FCKGFEYSEKCDVYSFGIVLWEILTRCRPYYDYPYMPMIFQDPFEEMFMMVCDKGLRPPIPPIWQNHHKMCPCPDCPPSMKKLMQDCWDHDPEKRPS

IKKLIESI
 ..... .
FQEILKRL

S_TKc odr-1.AA S_TKc 479-754 15 4.9e-09 -44.44 SMART 1-231 (231) Show / Hide
Range on Protein: 479-754
Range on HMM: 1-231/231
Sequence Identity: 15% (46 aa)

TSRRRVFGSYALVGTQRAEYVQ------FKQIRKINFPETTLDYLYSLKQLQHDNLAKFYGIQVNDDIMTMTILHTLVER--GTLEEFCLDRDFG-----
    |. |. |     ..  .        |.|.     |...  .  ||. .|.|. |.|.. ..     . .   ...   |.| ..  .|  .     
YEILRKIGKGAFGKVYKCRHKKTGRIVAIKIIK-----EHIRREIQILKK-HHPNIVKLYDVFQD---DHLYMVMEYCDGDLGDLFDYIKKRGRHGLRFP

MDDTFKSAFMRDILKGLQYLHKSSIGYHGHLQASTCLIDINWVLKLTLYGVSNFMSDQLDAENIKVPEQAAHMITYPQYVCFPPEHIREYDDSGKQPPRV
..      .|. |...|.|.|.  |  |  |  .  |.|   ..|..  |.. ..                ...  | |.  .|| .             
FPE-HARFYMYQICCALEYCHSHGI-IHRDLKPENILLDE--HIKICDFGLARQL---------------TTFCGTPWYM--APEVL-------------

VRGSP-KGDIYCVGMIFYMMVEREDPYHLIHSVERPNATLIKQILNENHMPRITDDYRQENMLLEMCKECWDRNPDKRPTIKKLIE-------SIST
   .. | |.. .| |.| |. .. |..         ....|.|.                 .... . |....|.||||. .. .           
-GYGKCKCDWWSCGCILYEMLCGYPPFP-------QMQMMFKKIG--------------SPEAKDFIRKCLQKDPEKRPTA-EALQDEWDIKCHPWF

Kinase odr-1.AA TTK 715-748 37 1e-06 17.89 In-house 304-338 (344) Show / Hide
Range on Protein: 715-748
Range on HMM: 304-338/344
Sequence Identity: 37% (13 aa)

PRITDDY-RQENMLLEMCKECWDRNPDKRPTIKKL
| ..  | . . ||... | |  |||.||..| .|
PEHPPYYEKINKMLIHVMKCCLYRNPKKRWSIPEL

Kinase odr-1.AA Fer 701-753 24 2e-06 17.91 In-house 228-283 (283) Show / Hide
Range on Protein: 701-753
Range on HMM: 228-283/283
Sequence Identity: 24% (14 aa)

NATL----IKQILNENHMPRITDDYRQENMLLEMCKECWDRNPDKRPTIKKLIESIS
....    .|.| ....|.....    | | . |.| ||...|..||| |.... . 
MTNVKKQARKWIIKKGYMMPMPNHMPPEIMQI-MMKQCWQKDPEDRPTMKEICQKLK

Kinase odr-1.AA LRRK 703-754 22 2e-06 18.53 In-house 296-351 (351) Show / Hide
Range on Protein: 703-754
Range on HMM: 296-351/351
Sequence Identity: 22% (13 aa)

TLIKQILNENHMPRITDDYRQEN-----MLLEMCKECWDRNPDKRPTIKKLIESIST
..|... .| . | |  .| .       |...  ..||. .|.|||.  . .. .|.
EQIEDKIIEGLRPTIPQHY-CPPCQPWHMYQDLIQHCWQHDPKKRPHFSQIVKRLSQ

Kinase odr-1.AA TK 729-752 33 3e-06 16.23 In-house 463-486 (486) Show / Hide
Range on Protein: 729-752
Range on HMM: 463-486/486
Sequence Identity: 33% (8 aa)

EMCKECWDRNPDKRPTIKKLIESI
.....||...|..||| . | | .
DLMQQCWHYDPEDRPTFSQLHEQL

Kinase odr-1.AA TKL-ciliate1 673-752 23 2.1e-05 14.44 In-house 201-279 (279) Show / Hide
Range on Protein: 673-752
Range on HMM: 201-279/279
Sequence Identity: 23% (20 aa)

DIYCVGMIFYMMVEREDPYHLIHSVERPNATLIKQILNEN---HM--PRITDDYRQENMLLEMCKECWDRNPDKRPTIKKLIESI
||| .| . | .. |. |.  . ||    .  .. .  .     .    |  |. |.  . .. . ||..|| |||    .|. .
DIYAYGIVMYILCFRKTPFQQKMSV----INIMCYWCEFPGRPNLGPQFIHFDCPQN--FHNLMMRCWCQNPNKRPNFNEIIQIL

Kinase odr-1.AA STE 669-750 16 3.1e-05 14.57 In-house 246-353 (359) Show / Hide
Range on Protein: 669-750
Range on HMM: 246-353/359
Sequence Identity: 16% (18 aa)

SPKGDIYCVGMIFYMMVEREDPYHLIHSVERPNATLIKQILNE---------NHMPRITDDYRQE-----------------NMLLEMCKECWDRNPDKR
. | ||...|     |.. . |.|  |  .   .......  .         .. |.. |.  |.                   . .  . | ...|.||
DTKCDIWSLGCTIIEMATGKPPWHDMHPMRAMFMIPFNYHMQQQFEQLCIVNGPPPPLPDHLSQNEMISYGGSGTTYPHKWSPEFKDFINKCLQKDPNKR

PTIKKLIE
|| ..|..
PTASQLLK

TyrKc odr-1.AA TyrKc 479-752 11 4.1e-05 -139.97 SMART 1-280 (280) Show / Hide
Range on Protein: 479-752
Range on HMM: 1-280/280
Sequence Identity: 11% (42 aa)

TSRRRVFGSYALVGTQRAEYVQF----KQIRKINFPETTLDYLYSLKQL--QHDNLAKFYGIQVND-----DIMTMTILHTLVERGTLEEFCLDRD--FG
 .  .. |. |     ....       | ...    |  .. .  ...|  .|.|. ..||. . .      |  . |.  ... | | ..  ..   . 
ITLGKKLGEGAFGEVYKGTWK-IQVAVKMLKEDA-REDFMREARIMCKLGGHHPNIVRLYGVCTQQGRNFMYIEPLMIVMEYMPHGDLKDYLRKHRPKLC

MDDTFKSAFMRDILKGLQYLHKSSIGYHGHLQASTCLIDINWVLKLTLYGVSNFMSDQLDAENIKVPEQAAHMITYPQYVCFPPEHIREYDDSGKQPPRV
|.|  .  |. .| .| .|||.                                                                            ..
MKDLLS--FCWQIACGMEYLHSK---------------------------------------------------------------------------NC

V-------------------------RGSPKG-------DIYCV-----GM------------IFYM-----------------MVEREDPYHLI---HS
.                         |    .       | | .     |             |.|                  .  . .. .     . 
IHRDLAARNCLVGENHTVKISDFGLSRDIYDDDQQGESKDYYRKKEHKGGKTMLPIRWMAPECINYGKFTTKSDVWSFGVCMWEIFTYGQQPYPGMIQQ-

VERPNATLIKQILNENHMPRITDDYRQENM--------LLEMCKECWDRNPDKRPTIKKLIESI
   .|. .|... . . ||.  .||  . |        . .. |.||...|..||| . ..| .
-MMSNQEVIEYVKQGYRMPQPPNDY--P-MSFVCCPDEMYQIMKQCWHEDPEDRPTFSEIHECF

Kinase odr-1.AA Dicty4-Unclassified 523-617 29 8.2e-05 12.37 In-house 55-156 (263) Show / Hide
Range on Protein: 523-617
Range on HMM: 55-156/263
Sequence Identity: 29% (30 aa)

LQHDNLAKFYGIQVND--DIMTMTILHTLVERGTLEEFCL------DRDFGMDDTFKSAFMRDILKGLQYLHKSSIGYHGHLQASTCLIDINWVLKLTLY
.|| || | ||  .|      || |   .  .|.| |         ..   .|||   ..  || .|.|.||   .  |  . .|  |.| .   |    
IQHPNLVKCYGYCINPRSHKSTMCIVMEFMHKGNLFEVIHSKPSEQQQPIKLDDTLIIKYAFDIAQGMQHLHTRNF-IHRDIKSSNILMDKHFNIKIADF

GVS
|.|
GIS

Kinase odr-1.AA Pkinase_Tyr 732-752 38 9.6e-05 16.69 Pfam 250-270 (270) Show / Hide
Range on Protein: 732-752
Range on HMM: 250-270/270
Sequence Identity: 38% (8 aa)

KECWDRNPDKRPTIKKLIESI
|.||. .|..||| . ..| .
KQCWHYDPEDRPTFSEIHEQL

Kinase odr-1.AA Pkinase 669-752 16 0.000123 17.47 Pfam 190-293 (293) Show / Hide
Range on Protein: 669-752
Range on HMM: 190-293/293
Sequence Identity: 16% (17 aa)

SPKGDIYCVGMIFYMMVEREDPYHLIH----SVERPNATLIKQILNENHMPRITDDYRQ----------------ENMLLEMCKECWDRNPDKRPTIKKL
.|| |.. .| |.| |. .. |.   |    .  .... . .    ..| .. ... .                 .  ... .| |....| ||||.. .
GPKVDMWSCGCILYEMLCGRPPFP-GHCWHDN-HDQMQMICRIMGPPLHFDWPWWCSISYFFFRHWHFHWTFHNWSEECKDFIKWCLCKDPKKRPTAEQI

IES--I
 ..  .
LQHPWF

Kinase odr-1.AA Dicty4-Unclassified 732-752 42 0.001163 8.37 In-house 243-263 (263) Show / Hide
Range on Protein: 732-752
Range on HMM: 243-263/263
Sequence Identity: 42% (9 aa)

KECWDRNPDKRPTIKKLIESI
| ||   | ||||. . |.  
KWCWHNDPNKRPTMNQIIQYL

Kinase odr-1.AA STE 520-590 20 0.011915 5.33 In-house 82-173 (359) Show / Hide
Range on Protein: 520-590
Range on HMM: 82-173/359
Sequence Identity: 20% (19 aa)

LKQLQ--HDNLAKFYGIQVNDDIM-----TMTILHTLVERGTLEEFCL---DRDFGMD----------DTFKSAFMRDILKG-LQYLHKSSI
.|...  |.|  |.||  ....       .  |   ... |.|...      . ....           .  ... |.|||| |.|||.  |
MKKCNHMHPNIVKYYGCYFKEGHNHKNDDELWICMEYMDGGSLDDIIKHKYGCGKPLNHNRQHQHRFPESQIAYICRQILKGLLYYLHSHHI

Kinase odr-1.AA TKL-ciliate1 576-587 58 0.015541 4.49 In-house 110-121 (279) Show / Hide
Range on Protein: 576-587
Range on HMM: 110-121/279
Sequence Identity: 58% (7 aa)

RDILKGLQYLHK
.||..|.||||.
KDIAQGMQYLHM

Kinase odr-1.AA TK 520-592 8 0.118118 0.45 In-house 92-261 (486) Show / Hide
Range on Protein: 520-592
Range on HMM: 92-261/486
Sequence Identity: 8% (14 aa)

LKQLQ-----HDNLAKFYGIQVNDDIMT----------MTILHTLVERGT----LEEFCLD-RDFGMDDTFKSA--------------------------
.|...     |.|. ..||. . .. ..          . |.  ... |     | ..  . |. ...   ...                          
MKMMCHSLGHHPNIVRLYGVCTQGEPKPCFEVVVHQEPWMIVMEYMPHGDMDGSLRDYLRKCRPKFQHEQDCPDNQHNKYPPSKLHHCMKGDITYSHESN

-----------------------------------------------FMRDILKGLQYLHKSSI----GY
                                               ....| .|..|||.  .    ..
SPCPEEQDYDDDLIKDHPPPLTTKDLLQMAWQWCLTCKHQLTMHQLLMCWQIACGMEYLHSKNCEFIQNF

Kinase odr-1.AA Pkinase_Tyr 520-534 43 2.25143 1.89 Pfam 57-72 (270) Show / Hide
Range on Protein: 520-534
Range on HMM: 57-72/270
Sequence Identity: 43% (7 aa)

LKQL-QHDNLAKFYGI
.||| .|.|. ..||.
MKQLGHHPNIVRLYGV

Kinase odr-1.AA Pkinase 574-590 47 3.824902 1.59 Pfam 113-129 (293) Show / Hide
Range on Protein: 574-590
Range on HMM: 113-129/293
Sequence Identity: 47% (8 aa)

FMRDILKGLQYLHKSSI
.|. ||.||.|.|. .|
YMYQILRGLEYCHSMGI

CYCc odr-1.AA CYCc 791-985 36 1.3e-94 321.5 SMART 1-231 (231) Show / Hide
Range on Protein: 791-985
Range on HMM: 1-231/231
Sequence Identity: 36% (85 aa)

DAQMQTMRLLNEMLPASIAKDLKNGL-IMPPRSYESATVMFVQICDFNALMKRSSPEQVIAFLNDIYDQFDTVIKRHD-----AYKVETTGETYMVASGV
.......|||..|||...|..||.|.  ..| .|...|..|  |..|..|.....|.||. .|||.|..||..|.||.     .||||| |..|||.||.
MEKQKNDRLLCQMLPRHVANQLKQGRHPVWPPCYDCVTILFTDIVGFTNLCSWCTPMQVVNMLNDHYTRFDRIIDRHGCYHNYCYKVETIGDAYMVVSGC

PHENEG-------------------RHIFEVAEISLEIREISYIYVLQHDK----NYKLRIRIGFHAGPIAAGVIGIRSPRYCLFGDTVNFASRMQSNCP
|..||                    .|. ..|...|...|.. .. .|| .    ...||.|||.| ||...||.|||.||||.|||||| ||||.|.. 
PTRNEHNQCQCLHHWWTWCFWCFHWQHAQWIADWALDMVECMKTFHVQHHMGELPWNPLRMRIGIHTGPVVCGVVGIRMPRYCYFGDTVNMASRMESTGD

PNQIQTSEITARLL-------FDSHEYKFVK
|.||. || | ..|        ... . |  
PGQIHVSEETYWCLCLDQFERRRCGQFEFEP

Guanylate_cyc odr-1.AA Guanylate_cyc 818-996 37 4.6e-54 190.71 Pfam 1-203 (214) Show / Hide
Range on Protein: 818-996
Range on HMM: 1-203/214
Sequence Identity: 37% (76 aa)

MPPRSYESATVMFVQICDFNALMKRSS----PEQVIAFLNDIYDQFDTVIKRH--DAYKVETTGETYMVASGVPHE-----NEGRHIFEVAEISLEIREI
... .|.. |.|| .| .|.|.  |.|    |.|.. .|||.|  ||... .|  . |||.| | .||..||.| .     .   |.  .|...|.. | 
VYAQRYDCVTIMFADIVGFTAFCSRCSMNNMPMQCVRMLNDHYTCFDRLCDQHKFGCYKVKTIGDCYMCVSGLPPPCVQWCCCWHHAWCMADMALDMMEY

SYIYVLQHDKNYK------LRIRIGFHAGPIAAGVIG--IRSPRYCLFGDTVNFASRMQSNCPPN--QIQTSEITARLLFDSHEYKFVK----RGIVHVK
   .| .|..|.       ...||| | ||  |||||  .| ||||..||||| ||||.|.  |.  .|. || |.|.| .  .. |..    ||...||
CQ-QVNVHHFNREPPTWNCIQMRIGIHTGPVVAGVIGSFQRMPRYCVWGDTVNVASRMESTGVPGSCKIHVSEETYRCLKCHENFQFECHLQHRGEIPVK

GKGN
|||.
GKGK