Gene par-1 (Nematode worm)

par-1

Species: Nematode worm
Alias: zyg-14, H39E23.1a, H39E23.1, CE23838, aSWK042, par-1, H39E23.1A
External Links: Wormbase Link ,
Annotation: WormBase Physical Map location: V: 14143734-14114632, WormBase Genetic Map location: V:5.97699,

Classification

Group: CAMK
Family: CAMKL
Subfamily: MARK

Sequence

Name Sequence Type Origin Length Description Download
par-1.kin_dom Protein Kinase Domain Sugen global kinase HMM prediction 252 Kinase domain by global Sugen HMM Fasta, JSON
par-1.AA Protein Genbank 1192 None Fasta, JSON

Protein domain

Protein domains of par-1.AA. The domains are annotated by HMM profiles from Pfam and SMART, as well as in-house data which includes HMMs of each individual kinase group, family and subfamily. Here is domain list in details, including sequence identity, significance and alignment. In particular, you can find can find the best hit kinase group/family/subfamily, which is helpful to understand the relationship between kinases.Kinase domain and best hit kinase group/family/subfamily are highlighted in red and blue. Visualized by pviz.

Usage: Zoom in selected region by dragging mouse and zoom out by double-clicking.

Show/hide domain list
Domain Protein name Domain Name Range Identity (%) Significance Score Profile Source Profile Range (length) Alignment
Kinase par-1.AA MARK 170-421 57 7.4e-177 582.42 In-house 1-262 (262) Show / Hide 
Range on Protein: 170-421
Range on HMM: 1-262/262
Sequence Identity: 57% (150 aa)

YKLLKTIGKGNFAKVKLAKHVITGHEVAIKIIDKTALNP-SSLQKLFREVKIMKQLDHPNIVKLYQVME--TEQT-LYLVLEYASGGEVFDYLVAH--GR
||.|||||.|..|||||| |. || .|||||..|. ||.  ......||..|||.||||||.||..|.|  |||. .||..|||||||..||..||  ||
YKMLKTIGHGSYAKVKLACHKHTGRKVAIKIYEKFKLNDPQWMKNVMREIEIMKKLDHPNIIKLFHVIEQDTEQHQIYLIMEYASGGELYDYIKAHPNGR

MKEKEARAKFRQIVSAVQYLHSKNIIHRDLKAENLLLDQDM--NIKIADFGFSNTFSLGNKLDTFCGSPPYAAPELFSGKKYDGPEVDVWSLGVILYTLV
..|.|||. ||||||||.|.|||||.|||.|.||.|.|...  ||||.|||||. .  |.||.||||.|||.|||.|..|.||||.||.|||||.||..|
LHEEEARRIFRQIVSAVNYCHSKNIVHRDIKPENILIDENGNHNIKIIDFGFSICIPPGQKLNTFCGTPPYMAPEIFLKKPYDGPKVDIWSLGVVLYFMV

SGSLPFDGQN--LKELRERVLRGKYRIPFYMSTDCENLLKKFLVINPQRRSSLDNIMKDRWM
.|..||||..  .|||....|||||.||...|..|.||....|..|| .| ....|||..||
CGYFPFDGDTQDYKELYKKILRGKYDIPCHVSKECRNLIQRLLTVNPEERPTIEEIMKHPWM
Kinase par-1.AA CAMKL 170-421 47 3.5e-170 547.42 In-house 1-297 (297) Show / Hide 
Range on Protein: 170-421
Range on HMM: 1-297/297
Sequence Identity: 47% (142 aa)

YKLLKTIGKGNFAKVKLAKH-VITGHEVAIKIID--KTALNPSSLQK-----------LFREVKIMKQLD---HPNIVKLYQVMETEQT------LYLVL
|...||.|||.|.|||||.|  .||..|||||||  |. ..| ....           ..||..|||.|.   ||||.|||.|.||...      .|||.
YRIGKTLGKGSFGKVKLATHIRTTGEKVAIKIIDKKKIWNDPWMKKNKCGQKHESDMRIRREIQIMKMLNIGKHPNIIKLYEVIETPEHDIETKKIYLVM

EYASGGE--VFDYLVAH----GRMKEKEARAKFRQIVSAVQYLHSKNIIHRDLKAENLLLDQDM--NIKIADFGFSNTFS-L----GNKLDTFCGSPPYA
||.||||   |||.|.|    |||.|.|||  ||||||||.|.||..|.|||.|.||.|||...  ||||.|||||| .       |.||.||||||||.
EYCSGGEMDLFDYIVKHGHRRGRMPEHEARRYFRQIVSAVNYCHSHGIVHRDIKPENILLDENGNNNIKIIDFGFSNMYRPCIFGPGQKLKTFCGSPPYM

APELFSG--KKYDGPEVDVWSLGVILYTLVSGSLPFDGQNLK---------ELRERVLRGKYRIPFYMSTDCENLLKKFLVINPQRRSSLDNIMKDRWM
|||.|.|  |.||||.||.||.|||||..| | ||||.....         ....... ....|....| ||..|..| |. || .| ....||...||
APEIFQGNNKPYDGPKVDIWSCGVILYAMVCGYLPFDDDTYNKQGKDNIYLYWKIMCG-YYPPIWYHVS-DCRDLIRKMLQVNPEKRPTIHQIMNHPWM
Kinase par-1.AA QIK 170-421 59 1.9e-169 569.2 In-house 1-272 (272) Show / Hide 
Range on Protein: 170-421
Range on HMM: 1-272/272
Sequence Identity: 59% (161 aa)

YKLLKTIGKGNFAKVKLAKHVITGHEVAIKIIDKTALNPSSLQKLFREVKIMKQLDHPNIVKLYQVMETEQTLYLVLEYASGGEVFDYLVAHGR------
| . .|||||||| ||||.| ||  .||||||||..|. . |||..|||.|||.|.||.|.||||||||.. .|.| ||.|.|| ||||..|||      
YDIERTIGKGNFAVVKLARHRITKTKVAIKIIDKSQLDEENLQKCYREVQIMKMLYHPHIIKLYQVMETDDMMYIVTEYCSNGEMFDYLCKHGRKGVKMV

--------------MKEKEARAKFRQIVSAVQYLHSKNIIHRDLKAENLLLDQDMNIKIADFGFSNTFSLGNKLDTFCGSPPYAAPELFSGKKYDGPEVD
              |.|.||| .| ||.|||.|.|..||.||||||||.|||..|||||||||||| |  |  | |.||||||||||.| ||.||||.||
NSPDIGDQVLMGVPMAENEARRWFWQICSAVHYCHKRNIVHRDLKAENILLDNNMNIKIADFGFSNWFKQGQLLMTWCGSPPYAAPEMFEGKEYDGPKVD

VWSLGVILYTLVSGSLPFDGQNLKELRERVLRGKYRIPFYMSTDCENLLKKFLVINPQRRSSLDNIMKDRWM
.||.||.|| ||.|.|||||..|..||.||| ||.||||.||.||| | .. ||..|..| . ..|.. |||
IWSMGVVLYVLVCGALPFDGKTLQNLRQRVLSGKFRIPFFMSQDCEHLIRHMLVVDPEHRYTIMQICQHRWM
Kinase par-1.AA CAMK 175-421 31 4.1e-142 461.11 In-house 1-425 (425) Show / Hide 
Range on Protein: 175-421
Range on HMM: 1-425/425
Sequence Identity: 31% (133 aa)

TIGKGNFAKVKLAKHVITG------------HEVAIKIIDKTALN--------------------------PSSLQKLFREVKIMKQ-------LDHPNI
|.|.|.|.||||..|  |.            ..||||||||. |                           |.......||..|||.       ||||||
TLGRGSFGKVKLCIHKNTTGKERVHHIYTNGQKVAIKIIDKKKLKDKQNQDYSNCYKIDKSKCKHRYCWRRPKDRKNVRREIEIMKKLQGIGNKLDHPNI

VKLYQVME------------TEQT--------LYLVL---EYASGG----EVFDYLVAH---------------GRMKEKEARAKFRQIVSAVQYLHSKN
.|||.|.|            | ..        .|.|.   ||.|||    ..|||.|.|               ||..|.|||  ||||.|||.|.||.|
IKLYEVYEDPHYFKNTNDYET-SKQVFTKDKHMYMVMEIMEYCSGGELFDDLFDYIVEHGCYGEEFDQFDIVERGRFTEREARRYFRQICSAVHYCHSHN

IIHRDLKAENLLLDQDM-----------------NIKIADFGFSNTFSL------------------------GNKLDTFCGSPPYAA-PELFSG-----
|.||||| ||.|||...                 ||||.||||.| |                          | |. ||||.|.|.| ||...|     
IVHRDLKPENILLDDNNDDSDPVEHDEIFDWNNNNIKIIDFGFANKFDPGENNFMCSDYKGGEMHNQWTTPTEGQKMKTFCGTPEYMAAPEVLNGKGHCN

--------KKYDGPEVDVWSLGVILYTLVSGSLPFDGQ-------------NLKELRERVLRGKYR-IPFYMST-----------------------DCE
        |.|.||..|.||.|||||....| .||.|              |..|| |....|||. .|.|.|.                       .| 
MQNATDEEKPYYGPKCDMWSCGVILYIMLCGYPPFYGDCDNEICEDEWIGMNDYELFEKIMKGKYDFPPPYFSPISCNYGPEWWDDISDEFHHFVSQECK

NLLKKFLVINPQRRSSLDNIMKDRWM
.|..| |. .|..| ... .... ||
DLIRKMLQVDPEKRMTIEQCLNHPWM
Kinase par-1.AA AMPK 170-421 48 5.1e-142 424.38 In-house 1-254 (254) Show / Hide 
Range on Protein: 170-421
Range on HMM: 1-254/254
Sequence Identity: 48% (123 aa)

YKLLKTIGKGNFAKVKLAKHVITGHEVAIKIIDKTALNPSSLQ-KLFREVKIMKQLDHPNIVKLYQVM-ETEQTLYLVLEYASGGEVFDYLVAHGRMKEK
| . ||||.| | |||...| .||..|||||..|. .  .. . .. ||..|.| . ||.|..||.|  ||.. ...|.||.|||| ||| | |||..|.
YIIGKTIGEGTFGKVKMGTHILTGEKVAIKILNKQKIKDQDMVERIQREIHILKLFRHPHIIQLYEVIIETPTDIFMVMEYVSGGELFDYIVKHGRLQER

EARAKFRQIVSAVQYLHSKNIIHRDLKAENLLLDQDMNIKIADFGFSNTFSLGNKLDTFCGSPPYAAPELFSGKKYDGPEVDVWSLGVILYTLVSGSLPF
||.  | ||.|.| |.|  .| ||||| ||||||...||||.||| ||. . |..| | |||| |||||. |||.| |||||.|| ||||| .. | |||
EACRFFQQIISGVEYCHRHMIVHRDLKPENLLLDHNKNIKIVDFGLSNMMKDGEFLKTACGSPCYAAPEMISGKLYCGPEVDIWSCGVILYAMLCGYLPF

DGQNLKELRERVLRGKYRIPFYMSTDCENLLKKFLVINPQRRSSLDNIMKDRWM
| .|  .|  ... |.| || ..|.....|.|. |  .|. | . . |... | 
DDENTPTLYKKIKNGEYYIPKFLSPEAKDLIKHMLQVDPMKRITIHDIRNHPWF
Kinase par-1.AA NuaK 170-421 48 1.2e-136 361.97 In-house 1-252 (252) Show / Hide 
Range on Protein: 170-421
Range on HMM: 1-252/252
Sequence Identity: 48% (123 aa)

YKLLKTIGKGNFAKVKLAKHVITGHEVAIKIIDKTAL-NPSSLQKLFREVKIMKQLDHPNIVKLYQVMETEQTLYLVLEYASGGEVFDYLVAHGRMKEKE
|...|| ||| . |||||    || ||||| | | .   .  . .  ||..||  |.||.|.. | | |  . . .|.||||||| .||.   ... |.|
YEFQKTLGKGTYGKVKLATEHSTGREVAIKSIKKCKIEDEQDMVHIRREIEIMSSLNHPHIIHIYEVFENKDKIVIVMEYASGGELYDYISECKSLPERE

ARAKFRQIVSAVQYLHSKNIIHRDLKAENLLLDQDMNIKIADFGFSNTFSLGNKLDTFCGSPPYAAPELFSGKKYDGPEVDVWSLGVILYTLVSGSLPFD
||  |||||||| | |  .|.||||| || ||||. |.|||||| || .. .. | |||||| || ||   |. | ||||| |||||.|||.| |..|||
ARHFFRQIVSAVHYCHKHRICHRDLKLENILLDQNCNAKIADFGLSNYYHDQKFLHTFCGSPLYASPEIVNGQPYHGPEVDCWSLGVLLYTMVYGTMPFD

GQNLKELRERVLRGKYRIPFYMSTDCENLLKKFLVINPQRRSSLDNIMKDRWM
|.. |.|   . .|.|. |   |. |. |  . | .||.|| .. .| .  |.
GHDFKHLVKQISQGAYYEPCKPSDACM-LIRWMLMVNPRRRATIYDICHHWWV
Kinase par-1.AA NIM1 170-421 43 5.5e-118 348.17 In-house 1-258 (258) Show / Hide 
Range on Protein: 170-421
Range on HMM: 1-258/258
Sequence Identity: 43% (112 aa)

YKLLKTIGKGNFAKVKLAKHVITGHEVAIKIID--KTALNPSSLQKLFREVKIMKQLDHPNIVKLYQVMETEQTLYLVLEYASGGEVFDYLVAHGRMKEK
| . . || ||| ||||. |  |   |||||.|  || .    .  | ||.  | .. |||||.|| | ||   ..||.|||.||| . .    | . | 
YRFCGEIGRGNFSKVKLGVHQLTKEKVAIKIMDLDKTKMDQKTQRMLSREIQCMECMHHPNIVRLYEVVETLTRVHLVMEYARGGELYTHIHQEGKLREI

EARAKFRQIVSAVQYLHSKNIIHRDLKAENLLLDQDMNIKIADFGFSNTFSL----GNKLDTFCGSPPYAAPELFSGKKYDGPEVDVWSLGVILYTLVSG
..   | ||||||.  ||.||.|||.|||| ..     .|..|||||         . .|.||||||||||||||.   | |. |||| ||..||  . |
HCKPIFAQIVSAVKHMHSRNIVHRDIKAENVMYTSNNCVKVGDFGFSCYCKMGTGANQMLNTFCGSPPYAAPELFQDEHYIGEYVDVWALGILLYFMMTG

SLPFDGQNLKELRERVLRGKYRIPFYMSTDCENLLKKFLVINPQRRSSLDNIMKDRWM
  ||      ..   .| |.| || | |  |  | .  |   |  |   | .|.. ||
VMPFRAETVPKMKKCILKGQYQIPDYVSLPCHRLIRGMLKHIPTQRYTIDQMMNHQWM
Kinase par-1.AA BRSK 170-421 52 2e-114 386.44 In-house 1-254 (254) Show / Hide 
Range on Protein: 170-421
Range on HMM: 1-254/254
Sequence Identity: 52% (134 aa)

YKLLKTIGKGNFAKVKLAKHVITGHEVAIKIIDKTALN--PSSLQKLFREVKIMKQLDHPNIVKLYQVMETEQTLYLVLEYASGGEVFDYLVAHGRMKEK
|.| || |||   .|||  | .||  |||||| |  |   .| |.|  ||. |||  |||.. |.| | |.   |||.||. |||| |||||  ||.. |
YRLEKTLGKGQTGLVKLGVHCVTGKKVAIKIINKEKLSNKESMLMKVEREIAIMKLIDHPHVMKMYDVYENKKYLYLILEHVSGGELFDYLVKKGRLTPK

EARAKFRQIVSAVQYLHSKNIIHRDLKAENLLLDQDMNIKIADFGFSNTFSLGNKLDTFCGSPPYAAPELFSGKKYDGPEVDVWSLGVILYTLVSGSLPF
|||  ||||.||. . ||.|| ||||| |||||| . ||||||||       .  |.| |||| || ||  .| ||||   |||| ||||| |  | |||
EARKFFRQIISALDFCHSHNICHRDLKPENLLLDEKNNIKIADFGMASLQVKDMMLHTSCGSPHYACPEVIRGEKYDGRKADVWSCGVILYALLVGALPF

DGQNLKELRERVLRGKYRIPFYMSTDCENLLKKFLVINPQRRSSLDNIMKDRWM
|  || .| |.| || . .| .   || .||.. . ..|..| || .| |  | 
DDDNLRQLLEKVKRGVFHMPHFIHPDCQDLLRGMIEVDPDKRISLKEIQKHPWY
Kinase par-1.AA S_TKc 170-421 35 3.5e-110 373.26 SMART 1-231 (231) Show / Hide 
Range on Protein: 170-421
Range on HMM: 1-231/231
Sequence Identity: 35% (96 aa)

YKLLKTIGKGNFAKVKLAKHVITGHEVAIKIIDKTALNPSSLQKLFREVKIMKQLDHPNIVKLYQVMETEQTLYLVLEYASG--GEVFDYLVAHGR----
|..|..|||| |.||....|. ||..||||||.         ... ||..|.|. .|||||||| |... . ||.|.||..|  |..|||.. .||    
YEILRKIGKGAFGKVYKCRHKKTGRIVAIKIIK---------EHIRREIQILKK-HHPNIVKLYDVFQD-DHLYMVMEYCDGDLGDLFDYIKKRGRHGLR

--MKEKEARAKFRQIVSAVQYLHSKNIIHRDLKAENLLLDQDMNIKIADFGFSNTFSLGNKLDTFCGSPPYAAPELFSGKKYDGPEVDVWSLGVILYTLV
  . | .||  ..||..|..|.||..||||||| ||.|||.  .|||.|||..  .      .||||.| | |||..   .|.....|.||.|.||| ..
FPFPE-HARFYMYQICCALEYCHSHGIIHRDLKPENILLDE--HIKICDFGLARQL------TTFCGTPWYMAPEVL---GYGKCKCDWWSCGCILYEML

SGSLPFDGQNLKELRERVLRGKYRIPFYMSTDCENLLKKFLVINPQRRSSLDNIMK-------DRWM
.|  ||.  ..... ....          | .. ....| |. .|..| .   ...       . |.
CGYPPFP--QMQMMFKKIG----------SPEAKDFIRKCLQKDPEKRPTA-EALQDEWDIKCHPWF
Kinase par-1.AA TSSK 170-421 37 5.1e-104 342.29 In-house 1-289 (289) Show / Hide 
Range on Protein: 170-421
Range on HMM: 1-289/289
Sequence Identity: 37% (108 aa)

YKLLKTIGKGNFAKVKLAKHVITGHE----------------VAIKIIDKTALNPSSLQK-LFREVKIMKQ-LDHPNIVKLYQVMETEQ-TLYLVLEYAS
|.. |.||.|..|||..| .  .  .                |||||||..   .  |.| | || .||.. |.||||...|.  ||.|   |.|.|||.
YNVGKKIGHGSYAKVYCAYSKKHKCKHNPRLRDDLRIKRHTHVAIKIIDRKKAPTDYLNKFLPREIQIMRKTLKHPNIIQFYEMFETCQGKIYMVMEYAE

GGEVFDYLVAH------GRMKEKEARAKFRQIVSAVQYLHSKNIIHRDLKAENLLLDQDMNIKIADFGFSNTFSLGN------KLDTFCGSPPYAAPELF
.| ...|  ..      |...|..||. |||.||||.|.||.|. ||||| ||.||| . |||..||||.. .. .       .. |||||  ||||| .
HGDLLEYIQRRTQERCCGALHEEQARKWFRQMVSAVKYCHSHNVVHRDLKCENILLDKHWNIKLTDFGFARYWPRDDPGRCCHLSKTFCGSYAYAAPEIL

SGKKYDGPEVDVWSLGVILYTLVSGSLPFDG--QNLKELRERVL-RG-KYRI--PFYMSTDCENLLKKFLVINPQRRSSLDNIMKDRWM
 |..||.  .||||.|||||..| |..|||   .|.. . ...  .. ....      |..| .|... | ..| .| ... |... ||
RGIPYDPKWYDVWSMGVILYIMVCGCMPFDDDKSNIHKMLWQQQEHKVCFPKPHSCWISQECKDLIRHMLQPHPCNRPHINEICHHCWM
Kinase par-1.AA Pkinase 170-421 33 6.1e-103 353.1 Pfam 1-293 (293) Show / Hide 
Range on Protein: 170-421
Range on HMM: 1-293/293
Sequence Identity: 33% (99 aa)

YKLLKTIGKGNFAKVKLAKHVITGHEVAIKIIDKTALNPSSLQKLFR--EVKIMKQLDHPNIVKLYQVMETEQTLYLVLEYASGG----EVFDYLV--AH
|.....||.|.|..|....|. ||..||.|||.|   ... .| ..|  |..||| |.|||||.|| ..|... .|.|.||. ||    . |||.   .|
YHIGRKIGSGSFGCVYKCHHKGTGKIVAVKIIKKRHEKSWKDQTHRRLSEIQIMKRLNHPNIVRLYDWFEDKDHIYMVMEYCEGGLYVMDLFDYISTWRH

GRM--KEKEARAKFRQIVSAVQYLHSKNIIHRDLKAENLLLDQDMNI----KIADFGFSNT--FSLGNKLDTFCGSPPYAAPELFSGKKYDGPEVDVWSL
|..   |.|..  ..||.....|.||..||||||| ||.|.|....|    ||.|||..       .  ..||||.|.|.|||.  | .|.||.||.||.
GCFYFSEWECKFYMYQILRGLEYCHSMGIIHRDLKPENILIDNNGHIDACVKICDFGLAKQFDY-NNS-MTTFCGTPWYMAPEVIRGGQYYGPKVDMWSC

GVILYTLVSGSLPFDGQ------NLKELRERVLRGKYRIPFY---------------------MSTDCENLLKKFLVINPQRRSSLDNIMKDRWM
|.||| ...| .||.|.      . ... .|....... ...                     .| .|  ..|. |  .|..| . . |... |.
GCILYEMLCGRPPFPGHCWHDNHDQMQMICRIMGPPLHFDWPWWCSISYFFFRHWHFHWTFHNWSEECKDFIKWCLCKDPKKRPTAEQILQHPWF
Kinase par-1.AA SNRK 170-421 46 1.9e-101 332.99 In-house 1-254 (254) Show / Hide 
Range on Protein: 170-421
Range on HMM: 1-254/254
Sequence Identity: 46% (118 aa)

YKLLKTIGKGNFAKVKLAKHVITGHEVAIKIIDKTALNPSSLQKLFREVKIMKQLDHPNIVKLYQVMETEQTLYLVLEYASGGEVFDYLVAHGR-MKEKE
| | ||.|.| || ||||.|| ||  ||.|.|||| .   |  .||.||. ||   |||||.|| |..|   |||.||   |....||.. | . ..|. 
YDLEKTLGRGHFAVVKLARHVFTGEKVAVKVIDKTKMDEVSKAHLFQEVRCMKLVQHPNIVRLYEVIDTQTKLYLILELGDGYDMYDYIMKHEKGLCEDL

ARAKFRQIVSAVQYLHSKNIIHRDLKAENLLLDQDMN-IKIADFGFSNTFSLGNKLDTFCGSPPYAAPELFSGKKYDGPEVDVWSLGVILYTLVSGSLPF
||  |.||. |..| | . ..||||| || .  . .  .|. |||||| |  |.||.|.|||  |.|||.  | .|| | ||.|||||||| || | .||
ARKYFCQIMHAIDYCHQLHVVHRDLKPENVVFFEKQGMVKLTDFGFSNKFMPGEKLETSCGSLAYSAPEILLGDSYDAPAVDIWSLGVILYMLVCGQAPF

DGQNLKELRERVLRGKYRIPFYMSTDCENLLKKFLVINPQRRSSLDNIMKDRWM
.  |  |   ...  || .|  .|..| .|... || .|..| ||..|    |.
QEANDSETLTMIMDCKYTVPDHVSDECRDLIQSMLVRDPKKRASLEEIVSHSWV
Kinase par-1.AA Pkinase_Tyr 170-312 35 3.4e-33 113.03 Pfam 1-156 (270) Show / Hide 
Range on Protein: 170-312
Range on HMM: 1-156/270
Sequence Identity: 35% (56 aa)

YKLLKTIGKGNFAKVKLAKHV----ITGHEVAIKIIDKTALNPSS--LQKLFREVKIMKQL-DHPNIVKLYQVME-TEQT--LYLVLEYASGGEVFDYLV
 ...|..|.|.| .|....       |. .||.|.. |    ..   .....||.|||||| .|||||.|| |    ..   .|.|.||. .|   ||| 
ITFGKKLGEGAFGEVYKGTWKGDPDNTKIPVAVKML-KEGAMHEQNCREDFMREAKIMKQLGHHPNIVRLYGVCTDQGEPNQIYIVMEYMPHGDLLDYLR

AH----GRMKEKEARAKFRQIVSAVQYLHSKNIIHRDLKAENLLLDQDMNIKIADFG
.|    .. . |.     .|| .. .||.|||.||||| | | |.. .. .||.|||
KHREDKQPLTMKDLLQMCWQIAKGMEYLESKNCIHRDLAARNCLVTENNVVKICDFG
Kinase par-1.AA TyrKc 170-420 27 8.1e-32 112.94 SMART 1-280 (280) Show / Hide 
Range on Protein: 170-420
Range on HMM: 1-280/280
Sequence Identity: 27% (79 aa)

YKLLKTIGKGNFAKVKLAKHVITGHEVAIKIIDKTALNPSSLQKLFREVKIMKQL--DHPNIVKLYQVMETE-------QTLYLVLEYASGGEVFDYLVA
 .|.|..| |.| .| ...      .||.| . . |     .. . || .||..|  .|||||.|| |  ..       . |..|.||...|   ||| .
ITLGKKLGEGAFGEVYKGTWK---IQVAVKMLKEDA-----REDFMREARIMCKLGGHHPNIVRLYGVCTQQGRNFMYIEPLMIVMEYMPHGDLKDYLRK

HGR-MKEKEARAKFRQIVSAVQYLHSKNIIHRDLKAENLLLDQDMNIKIADFGFSNTFSLG------NKLDTF----CGS--PPYA--APELFSGKKYDG
|..  . |.      || .  .||||||.||||| | | |.. .  .||.||| |     .       .  .     .|    |.   ||| .  .|.  
HRPKLCMKDLLSFCWQIACGMEYLHSKNCIHRDLAARNCLVGENHTVKISDFGLSRDIYDDDQQGESKDYYRKKEHKGGKTMLPIRWMAPECINYGKFT-

PEVDVWSLGVILYTLVS-GSLPFDG-----QNLKELRERVLRG-KYRIPFY--------MSTDCENLLKKFLVINPQRRSSLDNIMKDRW
.. |||| || .. . . |  |  |      . .|..|.| .|   ..| .        ....  .. |.    .|  | .  .| ....
TKSDVWSFGVCMWEIFTYGQQPYPGMIQQMMSNQEVIEYVKQGYRMPQPPNDYPMSFVCCPDEMYQIMKQCWHEDPEDRPTFSEI-HECF
Kinase par-1.AA Pkinase_Tyr 349-387 34 0.032582 8.12 Pfam 196-236 (270) Show / Hide 
Range on Protein: 349-387
Range on HMM: 196-236/270
Sequence Identity: 34% (14 aa)

DVWSLGVILYTLVS-GSLP-FDGQNLKELRERVLRGKYRIP
|||| || .. ... |  | . |    |. |.. .  || |
DVWSFGVLMWEIFTYGEQPTYPGMSNEEVYEYIYEDGYRMP
UBA_CAMKL par-1.AA UBA_CAMKL 442-482 35 1.5e-11 39.66 In-house 1-41 (41) Show / Hide 
Range on Protein: 442-482
Range on HMM: 1-41/41
Sequence Identity: 35% (15 aa)

DEQRIEKLIQIFQLGFNKAAILESVEKEKF-EDIHATYLLLG
||..|. .....  ||.. .| ||... |.  .|.|||.||.
DEEIIQEMCKMW-HGFDREEIIESLRNNKYHNHITATYYLLL
UBA par-1.AA UBA 445-482 18 0.000117 22.72 SMART 1-38 (38) Show / Hide 
Range on Protein: 445-482
Range on HMM: 1-38/38
Sequence Identity: 18% (7 aa)

RIEKLIQIFQLGFNKAAILESVEKEKFEDIHATYLLLG
. ||. |. ..||.  ..... .. .  . .|...|. 
YEEKIDQLMEMGFDREECVQALRACNWNVEMAMNWLFS
KA1 par-1.AA KA1 1146-1192 43 4e-22 77.38 Pfam 1-48 (48) Show / Hide 
Range on Protein: 1146-1192
Range on HMM: 1-48/48
Sequence Identity: 43% (21 aa)

TDSLVQWEMEVCKLP-RLSLNGVRFKRISGTSIGFKNIASKIAQELNL
... |..|..|||.| ||.|.||.|||.|| .  .|....|| .|..|
EPEVVKFEIQVCKVPGRLGLYGVDFKRVSGNQWQYKDLCTKILKEMRL