Gene pkc-2 (Nematode worm)

pkc-2

Species: Nematode worm
Alias: kin-11, pkc-2, E01H11.1, CE30929, E01H11.1c, aSWK014
External Links: Wormbase Link ,
Annotation: WormBase Genetic Map location: n/a, WormBase Physical Map location: X: 9379903-9389774,

Classification

Group: AGC
Family: PKC
Subfamily: PKCa

Sequence

Name Sequence Type Origin Length Description Download
pkc-2.kin_dom Protein Kinase Domain Sugen global kinase HMM prediction 262 Kinase domain by global Sugen HMM Fasta, JSON
pkc-2.AA Protein Genbank 861 None Fasta, JSON

Protein domain

Protein domains of pkc-2.AA. The domains are annotated by HMM profiles from Pfam and SMART, as well as in-house data which includes HMMs of each individual kinase group, family and subfamily. Here is domain list in details, including sequence identity, significance and alignment. In particular, you can find can find the best hit kinase group/family/subfamily, which is helpful to understand the relationship between kinases.Kinase domain and best hit kinase group/family/subfamily are highlighted in red and blue. Visualized by pviz.

Usage: Zoom in selected region by dragging mouse and zoom out by double-clicking.

Show/hide domain list
Domain Protein name Domain Name Range Identity (%) Significance Score Profile Source Profile Range (length) Alignment
Kinase pkc-2.AA C1_1 104-156 43 1.1e-21 83.23 Pfam 1-55 (55) Show / Hide 
Range on Protein: 104-156
Range on HMM: 1-55/55
Sequence Identity: 43% (24 aa)

HKFIAR-FFKQPTFCSHCKDFLWG-ITKQGFQCQVCTLVVHKRCHEFVNFACPGA
|..... .|||||||.||..|.|| . .||..||.| ...|.|||..|.  |.. 
HHWVHHWNFKQPTFCCHCGEFCWGWLGHQGWKCQWCHYNCHHRCHMKVPPECGCN
Kinase pkc-2.AA C1 104-153 32 1.1e-18 69.34 SMART 1-61 (61) Show / Hide 
Range on Protein: 104-153
Range on HMM: 1-61/61
Sequence Identity: 32% (20 aa)

HKFIARFFKQPTFCSHCKDFLWGITKQ-----GFQCQVCTLVVHKRCHEFVNF-------AC
|..... | .||.|.||....||. ||     |..|..| ...||.||..|.        .|
HHWHWWRF-KPTYCCHCRKMIWGMFKQHWKMQGYRCSWCKYKCHKKCHDKVPQQSHQDGWMC
Kinase pkc-2.AA AGC 95-107 26 0.015036 0.81 In-house 377-395 (395) Show / Hide 
Range on Protein: 95-107
Range on HMM: 377-395/395
Sequence Identity: 26% (5 aa)

QKN------VHEIKSHKFI
..|      . |||.|.. 
GGNDFGDKGAEEIKNHPWF
Kinase pkc-2.AA C1_3 134-146 30 7.592841 1.11 Pfam 18-30 (30) Show / Hide 
Range on Protein: 134-146
Range on HMM: 18-30/30
Sequence Identity: 30% (4 aa)

CQVCTLVVHKRCH
|  |  ..|..| 
CMQCDFMLHEDCA
C1_1 pkc-2.AA C1_1 169-221 47 1.5e-21 82.74 Pfam 1-55 (55) Show / Hide 
Range on Protein: 169-221
Range on HMM: 1-55/55
Sequence Identity: 47% (26 aa)

HKWKVQ-TYSSPTFCDHCGSLLYG-ILHQGMKCQSCDTNVHHRCVKNVPNMCGTD
|.|..  .. .||||.|||....| . |||.||| |  |.||||...||..|| .
HHWVHHWNFKQPTFCCHCGEFCWGWLGHQGWKCQWCHYNCHHRCHMKVPPECGCN
C1 pkc-2.AA C1 169-218 29 1.2e-18 69.2 SMART 1-61 (61) Show / Hide 
Range on Protein: 169-218
Range on HMM: 1-61/61
Sequence Identity: 29% (18 aa)

HKWKVQTYSSPTFCDHCGSLLYGILHQ-----GMKCQSCDTNVHHRCVKNVPN-------MC
|.|. ... .||.|.||.....|. .|     |..|. |. ..|..|...||.       ||
HHWHWWRF-KPTYCCHCRKMIWGMFKQHWKMQGYRCSWCKYKCHKKCHDKVPQQSHQDGWMC
C1_3 pkc-2.AA C1_3 180-211 28 0.001382 10.62 Pfam 1-30 (30) Show / Hide 
Range on Protein: 180-211
Range on HMM: 1-30/30
Sequence Identity: 28% (9 aa)

TFCDHCGSLLYGILHQGMKCQSCDTNVHHRCV
 .|. ||  .|.  . . .|  || ..| .|.
FTCNCCGLPIYR--DPFYHCMQCDFMLHEDCA
C2 pkc-2.AA C2 240-328 47 6.1e-37 128.47 Pfam 1-90 (90) Show / Hide 
Range on Protein: 240-328
Range on HMM: 1-90/90
Sequence Identity: 47% (43 aa)

LTIKILEAKNLIPMD--PNGLSDPYVKCKLIPEDSGCKSKQKTKTLRATLNPQWNETFTYKLLPGDKDRRLSIEVWDWDRTSRNDFMGSLS
|.....||.|| |||  .||.||||||..| .... ..  .|||. . ||||.||||||. . | | ...| ..|||||| .|.||.|  .
LRVHVIEARNLPPMDWDKNGKSDPYVKVYLGGDPKDTQK-YKTKVIKNTLNPVWNETFTFDVPPPDLQHTLRFTVWDWDRFGRDDFIGQCC
C2 pkc-2.AA C2 239-343 28 5.6e-29 103.52 SMART 1-92 (92) Show / Hide 
Range on Protein: 239-343
Range on HMM: 1-92/92
Sequence Identity: 28% (35 aa)

QLTIKILEAKNLIPMDPNGLSDPYVKCKLIPEDSGCKSKQKTKTLRATL---NPQWNE---TFTYKLLPGDKDRRLSIEVWDWDRTSRNDFMGSLSFG--
.||..|.||.||.        ||||| .            |||. . ||   ||.|||   ||.... |    . | .||||.      ||.| ....  
TLTVHIIEARNLP--------DPYVKVY------------KTKVVKNTLSGFNPVWNEWMETFYFDVHP----Q-LRFEVWDH------DFIGHCCIPPN

------------ISELMKEAASGWY
            .|... .  . |.
NPHWHQWDGCIHLSDIL-GYRH-WW
Kinase pkc-2.AA Alpha 413-674 81 7.50000000001e-230 769.88 In-house 1-259 (259) Show / Hide 
Range on Protein: 413-674
Range on HMM: 1-259/259
Sequence Identity: 81% (213 aa)

FNFLTVLGKGSFGKVLLGEQKTTKELFAIKVLKKDVIIQDDDVECTMTEKRVLALPEKPSFLVALHSCFQTMDRLYFVMEFVNGGDLMYQIQQVGKFKEP
||||.||||||||||.|.|.|.|.||.|||.||||||||||||||||.||||||||.||.|||..|||||||||||||||.||||||||.||||||||||
FNFLMVLGKGSFGKVMLAERKGTDELYAIKILKKDVIIQDDDVECTMVEKRVLALPGKPPFLVQMHSCFQTMDRLYFVMEYVNGGDLMYHIQQVGKFKEP

VAVFYAAEIAVGLFFLHSKGIIYRDLKLDNVMLERDGHIKITDFGMCKENIFGDATTKTFCGTPDYIAPEIILYQPYGKSVDWWAYGVLLFEMLAGQPPF
.|||||||||.||||||.|||||||||||||||...|||||.||||||||...|.||.||||||||||||||.||||||||||||.||||.||.||||||
HAVFYAAEIAIGLFFLHEKGIIYRDLKLDNVMLDAEGHIKIADFGMCKENMWEDQTTRTFCGTPDYIAPEIIAYQPYGKSVDWWAFGVLLYEMMAGQPPF

DGEDEDELFTAITEHNVSYPKSLSKEAVSLCKALLIKNPSKRLGCTGDDESASRDIKEHPFF
|||||||||.||.|||||||||.|||||..||..|.|.|.|||||..|.|   .||.|||||
DGEDEDELFQAIMEHNVSYPKSMSKEAVDICKGFLTKHPNKRLGCGPDGE---QDIREHPFF
Kinase pkc-2.AA PKC 413-674 71 3.7e-217 710.7 In-house 1-262 (262) Show / Hide 
Range on Protein: 413-674
Range on HMM: 1-262/262
Sequence Identity: 71% (188 aa)

FNFLTVLGKGSFGKVLLGEQKTTKELFAIKVLKKDVIIQDDDVECTMTEKRVLALPEKPSFLVALHSCFQTMDRLYFVMEFVNGGDLMYQIQQVGKFKEP
||||.||||||||||.|.|.| |.|..||||||||||||||||||||||||||||..|. ||..||.||||||||.||||.|||||||..|||...|||.
FNFLKVLGKGSFGKVMLAERKGTDEYYAIKVLKKDVIIQDDDVECTMTEKRVLALAWKHPFLTHLHCCFQTMDRLFFVMEYVNGGDLMFHIQQQRRFKEE

VAVFYAAEIAVGLFFLHSKGIIYRDLKLDNVMLERDGHIKITDFGMCKENIFGDATTKTFCGTPDYIAPEIILYQPYGKSVDWWAYGVLLFEMLAGQPPF
.|.||||||...|.|||.|||||||||||||.|...|||||.||||||||.....||.|||||||||||||. ||.|||||||||.|||..||.|||.||
HARFYAAEIICALQFLHEKGIIYRDLKLDNVLLDHEGHIKIADFGMCKENMWNGDTTSTFCGTPDYIAPEILQYQEYGKSVDWWAFGVLMYEMMAGQSPF

DGEDEDELFTAITEHNVSYPKSLSKEAVSLCKALLIKNPSKRLGCTGDDESASRDIKEHPFF
.|||||||| .|...|..||..|||||||.||... |||.|||||. ..|....||.|||||
HGEDEDELFQSIMHDNPHYPRWLSKEAVSICKGFMTKNPEKRLGCHPQQEEGEQDIREHPFF
Kinase pkc-2.AA AGC 413-674 34 1.1e-190 498.57 In-house 1-395 (395) Show / Hide 
Range on Protein: 413-674
Range on HMM: 1-395/395
Sequence Identity: 34% (137 aa)

FNFLTVLGKGSFGKVLLGEQK------TTKELFAIKVLKKDV-IIQDD--DVECTMTE------------KRVLALPEK---------PSFLVA-LHSCF
|.||.|.|||||||| | . |      .|....|.|||||.. |....  .||.||||            ...|..  .           |.|  ||..|
FEFLKVIGKGSFGKVYLVRKKDGCHKKDTGKYYAMKVLKKKHKIVIKKKNMVEHTMTEHWKQDQGYVWEERNILEKCNHTHNHPIKSHHPFIVKILHYSF

QTMDR--LYFVME----FVN-----GG-DLMYQIQ---QVGKFKEPVAVFYAAE-------IAVGLFFLHS-KGIIYRD-LKLDNVMLERDGHIKITDFG
|. |.  ||||||    .||     || .|....|   . |.| |..| |||||       |. .| .||| .|||.|| ||..|..| .|||||.||||
QDKDHTYLYFVMEYMPRYVNDLYCGGGCELFLHLQGRRKEGRFDEERARFYAAEMQKICGCIVLALEYLHSHMGIIHRDYLKPENILLDEDGHIKLTDFG

MCKENIFGD--------------------------------------------------ATTKTFCG--TPDYIAPEIILYQPYGKSVDWWA--YGVLLF
.|||.. ..                                                  ..|.||||  ||.|.||||.    |||..|||.  .|.|..
LCKEGMNDGEKGQQSQSNMKFHWHNKKYQKSNMDTNKCNPNNWQRNNMSQEDDTTRKKRDRTWTFCGPCTPEYMAPEIL----YGKACDWWSFGLGCLMY

EMLAGQPPFDGE----------DEDELFTAIT------EHNVSYP----------KSLSKEAVSLCKALLIKNPSKRLGCTGDDES--ASRDIKEHPFF
|||.|.||| |.          ...|.|  |       ...| .|          ...|.||..|.| || |.|.||||| |.|..     .||.||.|
EMLTGYPPFYGDNPQENRHPFRNPMEMFQKIMNGRYFINWKVKFPFPEDPQFPEDRWFSPEAKDLIKKLLCKDPEKRLGCGGNDFGDKGAEEIKNHPWF
Kinase pkc-2.AA Eta 413-674 64 2e-153 516.01 In-house 1-261 (261) Show / Hide 
Range on Protein: 413-674
Range on HMM: 1-261/261
Sequence Identity: 64% (170 aa)

FNFLTVLGKGSFGKVLLGEQKTTKELFAIKVLKKDVIIQDDDVECTMTEKRVLALPEKPSFLVALHSCFQTMDRLYFVMEFVNGGDLMYQIQQVGKFKEP
|||. ||||||||||.| |.| | |..||||||||||||||||||||||||.|.| .|  || .||.|||| |||.||||.|||||||.|||.  || ||
FNFIKVLGKGSFGKVMLAERKGTDEVYAIKVLKKDVIIQDDDVECTMTEKRILSLARKHPFLTQLHCCFQTKDRLFFVMEYVNGGDLMFQIQRARKFDEP

VAVFYAAEIAVGLFFLHSKGIIYRDLKLDNVMLERDGHIKITDFGMCKENIFGDATTKTFCGTPDYIAPEIILYQPYGKSVDWWAYGVLLFEMLAGQPPF
 | |||||. . | ||| .|.|||||||||..|...|| |. ||||||| |  . || |||||||||||||.  . || |||||| |||..||..|||||
RARFYAAEVTCALMFLHQHGVIYRDLKLDNILLDHEGHCKLADFGMCKEGIMNGMTTTTFCGTPDYIAPEILQEMEYGPSVDWWAMGVLMYEMMCGQPPF

DGEDEDELFTAITEHNVSYPKSLSKEAVSLCKALLIKNPSKRLGCTG--DDESASRDIKEHPFF
. . ||.|| .| . .| ||  |.|||||. || . |||.|||||.   ..| |   |..||||
EADNEDDLFESILHDDVLYPVWLHKEAVSILKAFMTKNPHKRLGCMTAQGGEHA---IRQHPFF
Kinase pkc-2.AA Delta 413-674 59 1.1e-140 473.68 In-house 1-259 (259) Show / Hide 
Range on Protein: 413-674
Range on HMM: 1-259/259
Sequence Identity: 59% (157 aa)

FNFLTVLGKGSFGKVLLGEQKTTKELFAIKVLKKDVIIQDDDVECTMTEKRVLALPEKPSFLVALHSCFQTMDRLYFVMEFVNGGDLMYQIQQVGKFKEP
|.|. ||||||||||.|.|.| ... .||| |||||...|||||||| |.|||||  .  ||  |   ||| . |.||||..||||||| |||...|.| 
FHFHKVLGKGSFGKVMLAELKGKNKYYAIKCLKKDVVLEDDDVECTMVERRVLALAWEHPFLCHLFCTFQTKEHLFFVMEYLNGGDLMYHIQQCHRFDEK

VAVFYAAEIAVGLFFLHSKGIIYRDLKLDNVMLERDGHIKITDFGMCKENIFGDATTKTFCGTPDYIAPEIILYQPYGKSVDWWAYGVLLFEMLAGQPPF
 | |||.|| .|| |||.|||||||||||||.|..|||||| ||||||||..|.....||||||||||||||  | | .|||||..|||..||| || ||
RARFYACEIICGLQFLHKKGIIYRDLKLDNVLLDCDGHIKIADFGMCKENMYGEKKASTFCGTPDYIAPEIIKGQKYNHSVDWWSFGVLMYEMLIGQSPF

DGEDEDELFTAITEHNVSYPKSLSKEAVSLCKALLIKNPSKRLGCTGDDESASRDIKEHPFF
 |||||||| .| . .  ||. ..||| .. |.|. ..| ||||    ...   ||..|.||
HGEDEDELFWSICNDRPWYPRWITKEAKDCLKKLFERDPEKRLGV---QYCPKGDIRQHCFF
Kinase pkc-2.AA Akt 413-674 49 1.9e-129 415.98 In-house 1-264 (264) Show / Hide 
Range on Protein: 413-674
Range on HMM: 1-264/264
Sequence Identity: 49% (132 aa)

FNFLTVLGKGSFGKVLLGEQKTTKELF-AIKVLKKDVIIQDDDVECTMTEKRVLALPEKPSFLVALHSCFQTMDRLYFVMEFVNGGDLMYQIQQVGKFKE
|.|| ||||||||||.| ..| |.... |.||||||.||| . || |.||...|     | |.| ||  ||| |.|||||...|||.| | .|. ..|.|
FDFLKVLGKGSFGKVFLVKKKDTQKWYYAMKVLKKDYIIQKNQVEHTKTERNILQHCNHP-FIVNLHYSFQTQDKLYFVMDYCNGGELFYHLQRKRRFSE

PVAVFYAAEIAVGLFFLHSKGIIYRD-LKLDNVMLERDGHIKITDFGMCKEN-IFGDATTKTFCGTPDYIAPEIILYQPYGKSVDWWA-YGVLLFEMLAG
. | ||.|||  .. .||||.||||| ||. |... .||||..||||.|||| |  . .|||||||| |.||||.. . ..|.||||.  |....||. |
DRARFYCAEIILAIEHLHSKNIIYRDYLKPENILMDKDGHICLTDFGLCKENIIKDHDKTKTFCGTPEYLAPEILNGNGHTKAVDWWGSLGCVMYEMMCG

QPPFDGEDEDELFTAITEHNVSYP--KSLSKEAVSLCKALLIKNPSKRLGCTGDDESASRDIKEHPFF
.|||  .| ...|  | . .| .|  . .|.|. .| . || |.|.|||| . .|    ..||.||.|
RPPFYNQDHHQMFKKIKNQPVKFPDKDWISPECKDLISGLLNKDPKKRLGGGPND---AQEIKRHPWF
Kinase pkc-2.AA SGK 413-674 41 4e-126 391.65 In-house 1-283 (283) Show / Hide 
Range on Protein: 413-674
Range on HMM: 1-283/283
Sequence Identity: 41% (120 aa)

FNFLTVLGKGSFGKVLLGEQKTT------------------KELFAIKVLKKDVII-------QDDDVECTMTEK-RVLALPEKPSFLVALHSCFQTMDR
| ||.|.||||||||.. . | .                  . ..|.|||.|. ||       .   .  .|.|.  .| .   | |.| ||  ||| . 
FDFLKVIGKGSFGKVYQVKHKDDETCQRVWLIFQSLLSQSEDKFYAMKVLQKQHIINEYRQDLKKKEQKHIMAERNVILKNMKHP-FIVNLHYAFQTKWK

LYFVMEFVNGGDLMYQIQQVGKFKEPVAVFYAAEIAVGLFFLHSKGIIYRDLKLDNVMLERDGHIKITDFGMCKENIFGDATTKTFCGTPDYIAPEIILY
|||||..||||.. | .|  ..|.|..| ||||||.  |  |||. ||||||| .|..|  .||...|||| |||.|    ||.|||||| | |||... 
LYFVMDYVNGGEMFYHLQREKHFPEDRARFYAAEIVCALEYLHSQDIIYRDLKPENILLDHQGHCCLTDFGLCKEGIKTNDTTFTFCGTPEYLAPEVLRK

QPYGKSVDWWAYGVLLFEMLAGQPPFDGEDEDELFTAITEHNVSYPKSLSKEAVSLCKALLIKNPSKRLGCTGDDESASRDIKEHPFF
||....||||  | .|.||. | |||   .  ...  |       |.. | .| .| . || |.|.||||   |    ...||.||||
QPHDRTVDWWCLGCVLYEMMYGLPPFYSRNKQQMYDNIINQPLQIPPQMSNDAWDLIQGLLQKDPKKRLGTKRD----FMEIKNHPFF
Kinase pkc-2.AA Iota 413-674 53 3e-119 399.01 In-house 1-271 (271) Show / Hide 
Range on Protein: 413-674
Range on HMM: 1-271/271
Sequence Identity: 53% (144 aa)

FNFLTVLGKGSFGKVLLGEQKTTKELFAIKVLKKDVIIQDDDVECTMTEKRVLALPEKPSFLVALHSCFQTMDRLYFVMEFVNGGDLMYQIQQVGKFKEP
|. ..|.|.||. |||. | | |. ..|.||.||... .|.|..   ||| |        ||| |||||||  ||.||.|||||||||. .|.  |  | 
FELIRVIGRGSYAKVLMVEHKKTRRIYAMKVIKKEMVNDDEDIDWVQTEKHVFEQASNHPFLVGLHSCFQTESRLFFVIEFVNGGDLMFHMQRQRKLPEE

VAVFYAAEIAVGLFFLHSKGIIYRDLKLDNVMLERDGHIKITDFGMCKENIFGDATTKTFCGTPDYIAPEIILYQPYGKSVDWWAYGVLLFEMLAGQPPF
 | ||.|||.. | |||..||||||||||||.|. .||||.||.|||||.|    || |||||| ||||||.  . || |||||| |||.|||.||  ||
HARFYSAEICLALNFLHERGIIYRDLKLDNVLLDHEGHIKLTDYGMCKEGIRPGDTTSTFCGTPNYIAPEILRGEDYGFSVDWWALGVLMFEMMAGRSPF

D--G-------EDEDELFTAITEHNVSYPKSLSKEAVSLCKALLIKNPSKRLGCTGDDESASRDIKEHPFF
|  |         || ||  | |...  |.|||  | .. |. | |.|  ||||  . . . .||||||||
DIVGNMDNPDQNTEDYLFQVILEKQIRIPRSLSVRAAHVLKGFLNKDPKERLGCHPQTNEGFMDIKEHPFF
Kinase pkc-2.AA AktR 413-674 41 1.7e-111 376.68 In-house 1-268 (268) Show / Hide 
Range on Protein: 413-674
Range on HMM: 1-268/268
Sequence Identity: 41% (112 aa)

FNFLTVLGKGSFGKVLLGEQK-TTKELFAIKVLKKDVIIQDDDVECTMTEKRVLALPEKPSFLVALHSCFQTMDRLYFVMEFVNGGDLMYQIQQVGKFKE
| .. .|||| |||| | . | ......|.|..||  ||.    . | ||. ...   . .|.| || |||| . |.|.||.. ||.| . ... .||.|
FHVYKCLGKGAFGKVYLVQKKRDNQKQYAMKMIKKKKIIERNQMHHTITERNIMEMCCNHPFIVKLHYCFQTKEKLFFIMEYCPGGELFQHLKKKKKFSE

PVAVFYAAEIAVGLFFLHSK-GIIYRDLKLDNVMLERDGHIKITDFGMCK-ENIF-GDATTKTFCGTPDYIAPEIILY-QPYGKSVDWWAYGVLLFEMLA
 .| ||.|.|  .| .||..  ||||||| .| .|. |||.||||||. | ...   | ....||||| |.|||.|.  ....||||||| |....||..
EQARFYFAQILLALEYLHQHMNIIYRDLKPENILLDEDGHVKITDFGLSKLQFMMHYDEKAYSFCGTPEYMAPEMITKKKGHNKSVDWWAFGIFIYEMVT

GQPPFDGEDEDELFTAITEHN---VSYPKSLSKEAVSLCK-ALLIKNPSKRLG--CTGDDESASRDIKEHPFF
|.|||. ..  ..|  | ...   . ||. .|... .|..  || ||| ||||  | |       .||.||.|
GCPPFYHKNQNQMFQKIKIKQQNKFPYPSYFSSQCKDLIQRKLLCKNPNKRLGYYCNG-----WEEIKSHPWF
Kinase pkc-2.AA PKN 413-674 49 5.9e-108 364.96 In-house 1-260 (260) Show / Hide 
Range on Protein: 413-674
Range on HMM: 1-260/260
Sequence Identity: 49% (132 aa)

FNFLTVLGKGSFGKVLLGEQKTTKELFAIKVLKKDVIIQDDDVECTMTEKRVLALPEKPS--FLVALHSCFQTMDRLYFVMEFVNGGDLMYQIQQVGKFK
| ...|||.| |||||| . |.| |..|||.|||  |.  |.||  |.|||...  ..    ||| |..|||| .  .||||.. ||||| .| .   |.
FRCIAVLGRGHFGKVLLSQYKHTGEYYAIKALKKQDIVARDEVESLMCEKRIFEVVNRMRHPFLVNLFACFQTEEHVCFVMEYAMGGDLMMHIHE-DVFS

EPVAVFYAAEIAVGLFFLHSKGIIYRDLKLDNVMLERDGHIKITDFGMCKENI-FGDATTKTFCGTPDYIAPEIILYQPYGKSVDWWAYGVLLFEMLAGQ
|| |.|||| . .|| .|| . ||||||||||..|...|..|| |||.|||.. .|| |  ||||||...|||..  . | . ||||  |||..||| | 
EPRACFYAACVVLGLQYLHEHKIIYRDLKLDNLLLDTEGYVKIADFGLCKEGMGYGDRTS-TFCGTPEFLAPEVLTDTSYTRAVDWWGLGVLIYEMLVGE

PPFDGEDEDELFTAITEHNVSYPKSLSKEAVSLCKALLIKNPSKRLGCTGDDESASRDIKEHPFF
.|| |.||.|.| .| ...| ||. || ||... . || ||| .||| .  |     ||| .|||
CPFPGDDEEEVFDCIVNDDVRYPRFLSVEAIAIMRRLLRKNPERRLGAGERD---AEDIKMQPFF
Kinase pkc-2.AA S_TKc 413-674 36 1.3e-96 328.22 SMART 1-231 (231) Show / Hide 
Range on Protein: 413-674
Range on HMM: 1-231/231
Sequence Identity: 36% (99 aa)

FNFLTVLGKGSFGKVLLGEQKTTKELFAIKVLKKDVIIQDDDVECTMTEKRVLALPEKPSFLVALHSCFQTMDRLYFVMEFVNG--GDLMYQIQQVGK--
. .| ..|||.|||| ..  | |....|||..|          | .. | ..|    .  ..| |. .||. |.||.|||...|  |||.  |.. |.  
YEILRKIGKGAFGKVYKCRHKKTGRIVAIKIIK----------EHIRREIQILKK--HHPNIVKLYDVFQD-DHLYMVMEYCDGDLGDLFDYIKKRGRHG

----FKEPVAVFYAAEIAVGLFFLHSKGIIYRDLKLDNVMLERDGHIKITDFGMCKENIFGDATTKTFCGTPDYIAPEIILYQPYGK-SVDWWAYGVLLF
    | | .| ||...|. .| ..||.|||.|||| .|..| .  ||||.|||....        .||||||.|.|||..   .||| ..|||. |..|.
LRFPFPE-HARFYMYQICCALEYCHSHGIIHRDLKPENILLDE--HIKICDFGLARQL-------TTFCGTPWYMAPEVL---GYGKCKCDWWSCGCILY

EMLAGQPPFDGEDEDELFTAITEHNVSYPKSLSKEAVSLCKALLIKNPSKRLGCTGDDESASRDIKEHPFF
|||.|.|||.  .....|  |           |.|| .. . .| |.|.||...    ..  .||| ||.|
EMLCGYPPFP--QMQMMFKKIG----------SPEAKDFIRKCLQKDPEKRPTA-EALQDE-WDIKCHPWF
Kinase pkc-2.AA Pkinase 413-674 30 2e-82 284.92 Pfam 1-293 (293) Show / Hide 
Range on Protein: 413-674
Range on HMM: 1-293/293
Sequence Identity: 30% (94 aa)

FNFLTVLGKGSFGKVLLGEQKTTKELFAIKVLKKDVIIQDDDVECTM-TEKRVLALPEKPSFLVALHSCFQTMDRLYFVMEFVNGG----DLMYQIQ--Q
. .. ..|.||||.| ..  | | ...|.|..||. .  . |.. .  .| ....   .  . | |. .|.. |..|.|||...||    ||.  |.  .
YHIGRKIGSGSFGCVYKCHHKGTGKIVAVKIIKKRHEKSWKDQTHRRLSEIQIMKRL-NHPNIVRLYDWFEDKDHIYMVMEYCEGGLYVMDLFDYISTWR

VGKF--KEPVAVFYAAEIAVGLFFLHSKGIIYRDLKLDNVMLERDGHI----KITDFGMCKEN-IFGDATTKTFCGTPDYIAPEIIL-YQPYGKSVDWWA
 |.|   | .. ||. .|. || ..||.|||.||||..|... ..|||    ||.||| .|   .  .  ..||||||.|.|||.|. .|.||..||.|.
HGCFYFSEWECKFYMYQILRGLEYCHSMGIIHRDLKPENILIDNNGHIDACVKICDFGLAKQFDY-NNS-MTTFCGTPWYMAPEVIRGGQYYGPKVDMWS

YGVLLFEMLAGQPPFDGE------DEDELFTAITEHNVSYPKSLS---------------------KEAVSLCKALLIKNPSKRLGCTGDDESASRDIKE
.|..|.||| |.|||.|.      |.....  | .  .... . .                     .|. ...| .| |.|.||..         ..|..
CGCILYEMLCGRPPFPGHCWHDNHDQMQMICRIMGPPLHFDWPWWCSISYFFFRHWHFHWTFHNWSEECKDFIKWCLCKDPKKRPT--------AEQILQ

HPFF
||.|
HPWF
Kinase pkc-2.AA S_TK_X 675-738 31 3.1e-16 61.16 SMART 1-79 (79) Show / Hide 
Range on Protein: 675-738
Range on HMM: 1-79/79
Sequence Identity: 31% (25 aa)

RRIDWFKIET--RQIQPPFKPKLK----TDRSTENFDHSFLKLPTKMTPPDWEVLENLKGDE---------FSNFSFVN
| ||| |..   ..|.||||||.|     .. |.|||  | . . . ||.|  ....   .|         | .|..|.
RGIDWDKLYNQQKEIEPPFKPKIKEVYASPTDTSNFDPEFTEETPMLTPDDPPLSNSMWQNEMETEIPPDPFRGFTYVF
Kinase pkc-2.AA TyrKc 413-655 22 7.7e-15 17.26 SMART 1-280 (280) Show / Hide 
Range on Protein: 413-655
Range on HMM: 1-280/280
Sequence Identity: 22% (64 aa)

FNFLTVLGKGSFGKVLLGEQKTTKELFAIKVLKKDVIIQDDDVECTMTEKRVLALP-EKPSFLVALHSCFQTM-------DRLYFVMEFVNGGDLMYQIQ
  .. .|| | ||.| .|. |   .  |.|.||.|       .|  | | |..     .   .|.|. .  .        . |. |||.. .|||   ..
ITLGKKLGEGAFGEVYKGTWK---IQVAVKMLKEDA------REDFMREARIMCKLGGHHPNIVRLYGVCTQQGRNFMYIEPLMIVMEYMPHGDLKDYLR

QVGK-FKEPVAVFYAAEIAVGLFFLHSKGIIYRDLKLDNVMLERDGHIKITDFGMCKENIFG-------DATTKTFCGTPD------YIAPEIILYQPYG
  .. .. .  . ..  || |  .||||..| |||   |... .....||.|||....   .       |  .|.  .  .        ||| | |  . 
KHRPKLCMKDLLSFCWQIACGMEYLHSKNCIHRDLAARNCLVGENHTVKISDFGLSRDIYDDDQQGESKDYYRKKEHKGGKTMLPIRWMAPECINYGKFT

KSVDWWAYGVLLFEMLA-GQPPFDG-----EDEDELFTAITEHNVSYPKSL---------SKEAVSLCKALLIKNPSKR---------L
   | |..||...|..  ||.|  |      . .|..  . . .   .            ..|  .. |     .|..|         .
TKSDVWSFGVCMWEIFTYGQQPYPGMIQQMMSNQEVIEYVKQGYRMPQPPNDYPMSFVCCPDEMYQIMKQCWHEDPEDRPTFSEIHECF
Kinase pkc-2.AA Pkinase_C 694-740 36 2.7e-12 46.56 Pfam 1-46 (46) Show / Hide 
Range on Protein: 694-740
Range on HMM: 1-46/46
Sequence Identity: 36% (17 aa)

KLKTDRSTENFDHSFLKLPTKMTPPDWEVLENLKGDEFSNFSFVNPF
..| .. |.|||. | . | . |||||. . . . ..| .|..|||.
QVKSPTDTSNFDPEFTDEPPMDTPPDWR-MSSGDQEPFRGFTYVNPD
Kinase pkc-2.AA Pkinase_Tyr 486-560 29 7e-09 30.71 Pfam 81-159 (270) Show / Hide 
Range on Protein: 486-560
Range on HMM: 81-159/270
Sequence Identity: 29% (23 aa)

RLYFVMEFVNGGDLMYQIQQ----VGKFKEPVAVFYAAEIAVGLFFLHSKGIIYRDLKLDNVMLERDGHIKITDFGMCK
..| |||.. .|||    ..     .... .  . ....|| |. .|.||..| |||   |.........||.|||...
QIYIVMEYMPHGDLLDYLRKHREDKQPLTMKDLLQMCWQIAKGMEYLESKNCIHRDLAARNCLVTENNVVKICDFGLAR
Kinase pkc-2.AA Pkinase_Tyr 413-447 38 0.001133 13.06 Pfam 1-39 (270) Show / Hide 
Range on Protein: 413-447
Range on HMM: 1-39/270
Sequence Identity: 38% (15 aa)

FNFLTVLGKGSFGKVLLGEQK----TTKELFAIKVLKKD
  |. .||.|.||.| .|. |     ||   |.|.|| .
ITFGKKLGEGAFGEVYKGTWKGDPDNTKIPVAVKMLKEG
Kinase pkc-2.AA Pkinase_Tyr 596-626 29 0.029224 8.28 Pfam 198-231 (270) Show / Hide 
Range on Protein: 596-626
Range on HMM: 198-231/270
Sequence Identity: 29% (10 aa)

WAYGVLLFEMLA-GQPP-FDGEDEDELFTAI-TE
|..|||..|..  |. | . | .  |.. .|  .
WSFGVLMWEIFTYGEQPTYPGMSNEEVYEYIYED
Pkinase_C pkc-2.AA Pkinase_C 810-856 51 1.5e-17 65.01 Pfam 1-46 (46) Show / Hide 
Range on Protein: 810-856
Range on HMM: 1-46/46
Sequence Identity: 51% (24 aa)

LLKSADDTSNFDSEFTHEVPKLTPIDRLFLMNLDQTEFEGFSFVNPE
 .||..|||||| ||| | |..|| |.  ... || .|.||..|||.
QVKSPTDTSNFDPEFTDEPPMDTPPDWR-MSSGDQEPFRGFTYVNPD
S_TK_X pkc-2.AA S_TK_X 804-854 36 4e-06 27.78 SMART 9-79 (79) Show / Hide 
Range on Protein: 804-854
Range on HMM: 9-79/79
Sequence Identity: 36% (26 aa)

YN---KIKV----LLK----SADDTSNFDSEFTHEVPKLTPIDRLFLMNLDQTE---------FEGFSFVN
||   .|.      .|    |. |||||| ||| |.|.|||.|.  ... .| |         |.||..|.
YNQQKEIEPPFKPKIKEVYASPTDTSNFDPEFTEETPMLTPDDPPLSNSMWQNEMETEIPPDPFRGFTYVF