Gene R02C2.1 (Nematode worm)

R02C2.1

Species: Nematode worm
Alias: CE21086, aSWK039, R02C2.1N, R02C2.1
External Links: Wormbase Link ,
Annotation: WormBase Physical Map location: V: 240264-236579, WormBase Genetic Map location: V:-19.23, Secondary Group: CAMK

Classification

Group: CAMK
Family: CAMKL
Subfamily: CHK1

Sequence

Name Sequence Type Origin Length Description Download
R02C2.1.kin_dom Protein Kinase Domain Sugen global kinase HMM prediction 263 Kinase domain by global Sugen HMM Fasta, JSON
R02C2.1.AA Protein Genbank 324 None Fasta, JSON
R02C2.1.kin_dom2 Protein Kinase Domain Sugen global kinase HMM prediction 217 Kinase domain by global Sugen HMM Fasta, JSON

Protein domain

Protein domains of R02C2.1.AA. The domains are annotated by HMM profiles from Pfam and SMART, as well as in-house data which includes HMMs of each individual kinase group, family and subfamily. Here is domain list in details, including sequence identity, significance and alignment. In particular, you can find can find the best hit kinase group/family/subfamily, which is helpful to understand the relationship between kinases.Kinase domain and best hit kinase group/family/subfamily are highlighted in red and blue. Visualized by pviz.

Usage: Zoom in selected region by dragging mouse and zoom out by double-clicking.

Show/hide domain list
Domain Protein name Domain Name Range Identity (%) Significance Score Profile Source Profile Range (length) Alignment
Kinase R02C2.1.AA CHK1 18-280 51 6.1e-185 620.69 In-house 1-276 (276) Show / Hide 
Range on Protein: 18-280
Range on HMM: 1-276/276
Sequence Identity: 51% (142 aa)

YEFIENLGEGSFAEVVLVAKVGTPNKMFAMKEISIVGKD-ECFMES-IKRECSIQKRLSKSR-HLNMIHLFEIRTNPENYQLILSYADGGDLFEKINQHG
||....||||.|..|.|......|....|||||.|.|.. .|||.. |..|..|||.|||.. | |.|.....|..||.|.|...||||||||.||....
YEVVQTLGEGAFGQVKLCENQRNPEEAVAMKEIHIKGQHKMCFMDNDIRKEYCIQKMLSKIGKHENVIRMMGMRMDPEFYYLFMEYADGGDLFDKIEPDC

GLGSDEAHRYFKQLIDGLRFIHEEG-VTHRDIKPENLLLTKSG------ILKIADFGFATMHR-FNGAEQMLNAYCGSPPYIAPEVLTGIDYRGPAVDIW
|..||||||||||||.||..||..| |||||||||||||.|..      .|||||||.||..| ..|.|.||...||.|||.||||.||..||||.||||
GMPSDEAHRYFKQLISGLKYIHCCGGVTHRDIKPENLLLDKHDSNDMPDNLKIADFGLATWYRRHDGEERMLDKRCGTPPYMAPEVCTGKQYRGPPVDIW

SAGVVLIAMIAGAVPWEQADHFDIFQSRYCSFRR-NGRKGAWSRMSQQVISLLRKILLQ-AELRATISMIEEDPWF
|.||||.||..|..||.|..|.|........... ......||......|.|||||| . .. ||||..||.|||.
SCGVVLMAMLTGELPWDQPSHMDCQEYCWWMDNKHWMHWCPWSKIDCRAICLLRKILCENPNKRATIEQIEKDPWY
Kinase R02C2.1.AA CAMKL 18-280 34 1.3e-117 376.96 In-house 1-297 (297) Show / Hide 
Range on Protein: 18-280
Range on HMM: 1-297/297
Sequence Identity: 34% (104 aa)

YEFIENLGEGSFAEVVLVAKVGTPNKMFAMKEISIVGKD-ECFMES------------IKRECSIQKRLSKSR-HLNMIHLFEIRTNPEN------YQLI
|.... ||.|||..| |   . |.... |.| | . ..  ...|..            |.|| .|.|.|. .. | | |.|.|....||.      ..|.
YRIGKTLGKGSFGKVKLATHIRTTGEKVAIKIIDKKKIWNDPWMKKNKCGQKHESDMRIRREIQIMKMLN-IGKHPNIIKLYEVIETPEHDIETKKIYLV

LSYADGGD--LFEKINQHGG----LGSDEAHRYFKQLIDGLRFIHEEGVTHRDIKPENLLLTKSG--ILKIADFGFATMHR-F-NGAEQMLNAYCGSPPY
. |..||.  ||..| .||.    .  .||.|||.|..... ..|. |. ||||||||.||...|   .||.||||..|.|   .| .|.|.  ||||||
MEYCSGGEMDLFDYIVKHGHRRGRMPEHEARRYFRQIVSAVNYCHSHGIVHRDIKPENILLDENGNNNIKIIDFGFSNMYRPCIFGPGQKLKTFCGSPPY

IAPEVLTG--IDYRGPAVDIWSAGVVLIAMIAGAVPWEQADH-----FDIFQSRYCSFRRNGRKGAWSRMSQQVISLLRKILLQ-AELRATISMIEEDPW
 |||.. |   .|.||.|||||.||.| ||. |..|......     ..|   .    .  ..   |...| ....|.||.|    | |.||  |...||
MAPEIFQGNNKPYDGPKVDIWSCGVILYAMVCGYLPFDDDTYNKQGKDNI-YLYWKIMCG-YYPPIWYHVS-DCRDLIRKMLQVNPEKRPTIHQIMNHPW

F
.
M
Kinase R02C2.1.AA CAMK 23-280 21 1.1e-88 285.77 In-house 1-425 (425) Show / Hide 
Range on Protein: 23-280
Range on HMM: 1-425/425
Sequence Identity: 21% (93 aa)

NLGEGSFAEVVLVAKVGTPN-----------KMFAMKEISI----------------VGKDECF----------MESIKRECSIQKRLSKSR----HLNM
 ||.|||..| |.    |..           . .|.| |.                 . | .|           .....|| .| |.|.. .    | | 
TLGRGSFGKVKLCIHKNTTGKERVHHIYTNGQKVAIKIIDKKKLKDKQNQDYSNCYKIDKSKCKHRYCWRRPKDRKNVRREIEIMKKLQGIGNKLDHPNI

IHLFEIRTN-------------------PENYQLIL---SYADGG----DLFEKINQHGG---------------LGSDEAHRYFKQLIDGLRFIHEEGV
|.|.|.  .                   .... ...    |..||    |||..| .||.               .  .||.|||.|........|. ..
IKLYEVYEDPHYFKNTNDYETSKQVFTKDKHMYMVMEIMEYCSGGELFDDLFDYIVEHGCYGEEFDQFDIVERGRFTEREARRYFRQICSAVHYCHSHNI

THRDIKPENLLLTKS-----------------GILKIADFGFATMHR----------FNGAEQMLNA-------------YCGSPPYIA-PEVLTG----
 |||.||||.||...                 . .||.|||||.. .          ..|.| | .              .||.|.|.| |||| |    
VHRDLKPENILLDDNNDDSDPVEHDEIFDWNNNNIKIIDFGFANKFDPGENNFMCSDYKGGE-M-HNQWTTPTEGQKMKTFCGTPEYMAAPEVLNGKGHC

---------IDYRGPAVDIWSAGVVLIAMIAGAVPWEQADHFDIF--------------QSRYCSFR-RNGRKGA---------WSRMSQQ--------V
         ..| ||..|.||.||.| .|  |  |..  .. .|.              . . . ..                 |.. |..        .
NMQNATDEEKPYYGPKCDMWSCGVILYIMLCGYPPFYGDCDNEICEDEWIGMNDYELFEKIMKGKYDFPPPYFSPISCNYGPEWWDDISDEFHHFVSQEC

ISLLRKILLQ-AELRATISMIEEDPWF
..|.||.|    | |.||. . ..||.
KDLIRKMLQVDPEKRMTIEQCLNHPWM
Kinase R02C2.1.AA S_TKc 18-280 27 2.1e-76 261.09 SMART 1-231 (231) Show / Hide 
Range on Protein: 18-280
Range on HMM: 1-231/231
Sequence Identity: 27% (77 aa)

YEFIENLGEGSFAEVVLVAKVGTPNKMFAMKEISIVGKDECFMESIKRECSIQKRLSKSRHLNMIHLFEIRTNPENYQLILSYADG--GDLFEKINQHGG
||... .|.|.|..| .. ...  .. .|.|.|.         |.|.|| .| |.    .| | ..|...  . ... ... |.||  ||||. | ..|.
YEILRKIGKGAFGKVYKCRHKK-TGRIVAIKIIK---------EHIRREIQILKK----HHPNIVKLYDVFQD-DHLYMVMEYCDGDLGDLFDYIKKRGR

------LGSDEAHRYFKQLIDGLRFIHEEGVTHRDIKPENLLLTKSGILKIADFGFATMHRFNGAEQMLNAYCGSPPYIAPEVLTGIDYRGPAVDIWSAG
      .   .| .|..|....| ..|. |. |||.||||.||..   .||.|||.|.           . .||.| |.|||||    | ....|.|| |
HGLRFPFPE-HARFYMYQICCALEYCHSHGIIHRDLKPENILLDE--HIKICDFGLARQL---------TTFCGTPWYMAPEVL---GYGKCKCDWWSCG

VVLIAMIAGAVPWEQADHFDIFQSRYCSFRRNGRKGAWSRMSQQVISLLRKILL-QAELRATISMIEE-------DPWF
..|. |..|  |..  ... .|.                  |.......||.|    | | |.  . .       .|||
CILYEMLCGYPPFP--QMQMMFKKIG---------------SPEAKDFIRKCLQKDPEKRPTA-EALQDEWDIKCHPWF
Kinase R02C2.1.AA Pkinase 18-280 26 7.8e-64 223.18 Pfam 1-293 (293) Show / Hide 
Range on Protein: 18-280
Range on HMM: 1-293/293
Sequence Identity: 26% (81 aa)

YEFIENLGEGSFAEVVLVAKVGTPNKMFAMKEISIVGKDECFMESIKR--ECSIQKRLSKSRHLNMIHLFEIRTNPENYQLILSYADGG----DLFEKIN
|.... .|.|||..| .  ..||.  ..|.|.|. ....... ..  |  |..| |||.   | | . |... ... .. ... |..||    |||. | 
YHIGRKIGSGSFGCVYKCHHKGTGK-IVAVKIIKKRHEKSWKDQTHRRLSEIQIMKRLN---HPNIVRLYDWFEDKDHIYMVMEYCEGGLYVMDLFDYIS

--QHGGL--GSDEAHRYFKQLIDGLRFIHEEGVTHRDIKPENLLLTKSGIL----KIADFGFATMHRFNGAEQMLNAYCGSPPYIAPEVLTGIDYRGPAV
  .||..    .|. .|..|.. || ..|..|. |||.||||.|. . | .    ||.|||.|  .. .   . .. .||.|.|.||||. |  | ||.|
TWRHGCFYFSEWECKFYMYQILRGLEYCHSMGIIHRDLKPENILIDNNGHIDACVKICDFGLAKQFD-Y-NNS-MTTFCGTPWYMAPEVIRGGQYYGPKV

DIWSAGVVLIAMIAGAVPWEQA-------DHFDIFQSRYCSFRRNGRKG----------------AWSRMSQQVISLLRKIL-LQAELRATISMIEEDPW
|.||.|..|. |. |  |. ..       . . |.. ... ....  .                    ..|.  .......| .  . | |.  | ..||
DMWSCGCILYEMLCGRPPFPGHCWHDNHDQMQMICRIMGPPLHFDWPWWCSISYFFFRHWHFHWTF-HNWSEECKDFIKWCLCKDPKKRPTAEQILQHPW

F
|
F
Kinase R02C2.1.AA AMPK 55-280 36 1e-57 169.92 In-house 38-254 (254) Show / Hide 
Range on Protein: 55-280
Range on HMM: 38-254/254
Sequence Identity: 36% (84 aa)

KDECFMESIKRECSIQKRLSKSRHLNMIHLFEIR-TNPENYQLILSYADGGDLFEKINQHGGLGSDEAHRYFKQLIDGLRFIHEEGVTHRDIKPENLLLT
||.  .|.|.|| .|   | . || . | |.|.    |.   ... |. ||.||. | .|| |  .|| |.|.| | |.  .|. .. ||| ||||||| 
KDQDMVERIQREIHI---LKLFRHPHIIQLYEVIIETPTDIFMVMEYVSGGELFDYIVKHGRLQEREACRFFQQIISGVEYCHRHMIVHRDLKPENLLLD

KSGILKIADFGFATMHRFNGAEQMLNAYCGSPPYIAPEVLTGIDYRGPAVDIWSAGVVLIAMIAGAVPWEQADHFDIFQSRYCSFRRNGRKGAWSRMSQQ
.   .||.|||   |   .   ..|   |||| | |||. .|  | || ||||| ||.| ||. |  | .  .  . ..       .||.    . .|..
HNKNIKIVDFGLSNMMKDG---EFLKTACGSPCYAAPEMISGKLYCGPEVDIWSCGVILYAMLCGYLPFDDENTPTLYKK-----IKNGEYYIPKFLSPE

VISLLRKILLQA-ELRATISMIEEDPWF
. .|....|    . |.||. | ..|||
AKDLIKHMLQVDPMKRITIHDIRNHPWF
Kinase R02C2.1.AA MARK 18-280 33 2.4e-54 176.12 In-house 1-262 (262) Show / Hide 
Range on Protein: 18-280
Range on HMM: 1-262/262
Sequence Identity: 33% (93 aa)

YEFIENLGEGSFAEVVLVAKVGTPNKMFAMKEISIVG---KDE-CFMESIKRECSIQKRLSKSRHLNMIHLFEIRT--NPEN-YQLILSYADGGDLFEKI
|...  .|.||.|.| |.  . |  . .| |   |.    ... . |....|| .| |.|.   | | | ||..    ....   ||. || ||.|.. |
YKMLKTIGHGSYAKVKLACHKHTG-RKVAIK---IYEKFKLNDPQWMKNVMREIEIMKKLD---HPNIIKLFHVIEQDTEQHQIYLIMEYASGGELYDYI

NQH--GGLGSDEAHRYFKQLIDGLRFIHEEGVTHRDIKPENLLLTKSG--ILKIADFGFATMHRFNGAEQMLNAYCGSPPYIAPEVLTGIDYRGPAVDIW
 .|  | |  .||.|.|.|.. .. . |. .. ||||||||.|. . |    ||.||||..       .|.||  ||.||| |||.. . .| ||.||||
KAHPNGRLHEEEARRIFRQIVSAVNYCHSKNIVHRDIKPENILIDENGNHNIKIIDFGFSIC---IPPGQKLNTFCGTPPYMAPEIFLKKPYDGPKVDIW

SAGVVLIAMIAGAVPWEQAD------HFDIFQSRYCSFRRNGRKGAWSRMSQQVISLLRKIL-LQAELRATISMIEEDPWF
| |||| .|. | .|.. ..      .. |   .|. . .         .| .  .|....| .  | |.||. |...||.
SLGVVLYFMVCGYFPFDGDTQDYKELYKKILRGKYDIPCH---------VSKECRNLIQRLLTVNPEERPTIEEIMKHPWM
Kinase R02C2.1.AA Ciliate-E2 18-280 20 6.3e-51 173.05 In-house 1-365 (365) Show / Hide 
Range on Protein: 18-280
Range on HMM: 1-365/365
Sequence Identity: 20% (78 aa)

YEFIENLGEGSFAEVVLVAKVGTPNKM-----------------FAMKE---ISIVGKDECFMESIKREC----------SIQKRLSKSRHLNMIHLFEI
|.||. .|.|.|. | .. .  ....                  ...|.    ..  ..  .........            .. |..  | | | ..| 
YKFIKKIGQGNFGSVYKCKVWKVQKQFAIKIIDQKQQRQQMQEKVKIKIYAMKIMKKNQIEQIKQEIHIMREINCFYKKINEKNILEQLNHPNIIKMYEC

RT--NPENYQLILSYADGGDLFEKINQHGGLG-----------SDEAHRYFKQLID---------------GLRFIHEEG-VTHRDIKPENLLLTKSGIL
    . .|. |.. |..|||||. |...                 |. ...||...               .|...|... . ||||||||.|.     .
FQEKDDNNIYLVMEYCQGGDLFDYIKNNKKKRNHEIEKDKYFTEKEIKYIMKQILQGFKTKAEFYIACIILALEYLHSKNNIIHRDIKPENILF-----I

KIADFGFAT---------MHRFNGAE---------------------QMLNAYCGSPPYIAPEVLTGIDY--------RGPAVDIWSAGVVLIAMIAGAV
||.|||...          | .....                     .| | .||.|.| |||.| | .|         . ..||||.||.|  |. |  
KIIDFGLSKKYDDDNQNRTH-KQQCKWYMFKNDTSRTPGYMDQIIQQNMFNTICGTPGYMAPEILNGKKYDNQQKQKGYDYKCDIWSLGVILYEMLFGKP

PWEQADHFDIFQSRYCSFRRNGR-----------KGAWSRMSQQVISLLRK-----ILLQAELRAT-ISMIEEDPWF
|.     ... .   ..|. .             |  |   ||... |..|     .  . | | | .. | . |||
PF-----QQQIKQCKIDFPCPEWQKDTQCIQCKWK-SWKKWSQECKDLIKKFGKRMLQKDPEKRITGWEQILNHPWF
Kinase R02C2.1.AA ULK 18-280 24 1.9e-50 173.89 In-house 1-329 (329) Show / Hide 
Range on Protein: 18-280
Range on HMM: 1-329/329
Sequence Identity: 24% (81 aa)

YEFIENLGEGSFAEVVLVAK-VGTP---NKMFAMKEIS-----IVGKD---ECFMESIKRECSIQKRLSKS-----RHLNMIHLFEIRTNP--ENYQLIL
|. .. ||.|||. .|  .. . |    |...| | |.     .  ..   . .....|.|. |.|.|        .| | . |...  ..   |. .|.
YCLNHCLGKGSFG-KVYKGRNKKTKDYVNEKVACKMIDKQKMNQKNNEQEGQYMWQLLKNEIKIMKKLKSPNRHKNHHPNIVKLYDWFETSNHNNIYIIM

SYADGGDLFEKINQHGGLGSDE----------AHRYFKQLIDGLRFIHEEGVTHRDIKPENLLLTKS------------GILKIADFGFATMHRFN---G
 | .||||.. |.....|. |.          |  .|||.. |....|.... ||||||.| |...             |.||||||||| .   .    
EYCNGGDLEQYIKKNKKLPEDTEEKKRLSEQEAIQFFKQILNGFKELHKHNIIHRDIKPQNILIHNGQPKTDSKKVHPNGVLKIADFGFAKHVDNDNMEQ

AEQMLNA----YCGSPPYIAPEVLT----GIDYRGPAVDIWSAGVVLIAMIAGAVPWEQADHFDIFQSRYCSFRRNG--------RKGAWSR-------M
.  |       .||.| | ||..|     ...|    .|||| |...  |. | .|..    .| .   . . ..|.         .    .        
QMMMTCVNEKRLCGTPLYMAPQILQGQGEQKPYYDYKCDIWSLGCIFYEMLYGKPPFYAW-FNDQYLQIIQKLINNPPPWPQQIKKQPLQFPKDGNDPQI

SQQVISLLRKIL-LQAELRATISMIEEDPWF
|.....|.|. |  . . | ..  . . |||
SPECKDLIRRMLQYDEKDRISWEELFNHPWF
Kinase R02C2.1.AA Ciliate-E2-Unclassified 18-280 21 2.3e-50 172.92 In-house 1-352 (352) Show / Hide 
Range on Protein: 18-280
Range on HMM: 1-352/352
Sequence Identity: 21% (76 aa)

YEFIENLGEGSFAEVVLVAKVGTPNKMFAMKEISIVGKDE-CFM------------ESIKRECSIQK--------RLSKSRHLNMIHLFEIRTNPENYQL
|..|. .|.|.|..| .. .  .  . .|||... . ..  . .            . .| . ..|.         |. . |.. ...|.. .. .|  .
YKIIKQIGQGGFGKVYKCQHKKQK-QYYAMKYMKKIQIYKQKQIMNKDEIMNEMKEMNNKKK-YHQRKYNKIMQQILLNHPHPFIVKMFYCFQDKQNIYI

ILSYADGGDLFEKINQHGG-----------------LGSDEAH-----RYFKQLIDGLRFIHEEG-VTHRDIKPENLLLTKSG---ILKIADFGFAT---
.. |..||||.. |.. ..                 .   .|      .||.|...|| ..|... . ||||||||.|....|    .||.|||..    
VMEYCEGGDLWQYIKKRKKQKQKGNDLFHNMKQRKIFTEQQAKYKKAKFYFAQILQGLEYLHHKNNIIHRDIKPENILFDNNGKNYYIKIIDFGISKKYQ

----MHRFNG-------AEQMLNAYCGSPPYI----APEVLTGIDYRGP---AVDIWSAGVVLIAMIAGAVPWEQADHFD---------------IFQSR
       .|.        .||..  ||.| |.    ||||| |  | ..   ..|||| ||.| .|. |  | .. .  .               .... 
QNNNCD-TNQQQKMQIWKQQMMWTFCGTPNYMPQYTAPEVLQGQNYDHSKAYKCDIWSLGVILYEMLFGYYPFYDNNCEQHQQLITQWINNAYRKQLYQN

YCSFRRNGRKGAW----SRMSQQVISLLR-----KILLQAELRATISMIEEDPWF
 .    . .|  |     . |.... ...     ..  . . | |.. | . |||
IKQKNIQFPKFPWQQIPKHWSPEAKDFINDLLQKMLKKNPNKRITFEQILNHPWF
Kinase R02C2.1.AA ULK 18-222 28 1e-46 161.54 In-house 1-255 (324) Show / Hide 
Range on Protein: 18-222
Range on HMM: 1-255/324
Sequence Identity: 28% (72 aa)

YEFIENLGEGSFAEVVLVAK-VGTP--NKMFAMKEIS-----IVGKD---ECFMESIKRECSIQKRLSKSRHLN--MIHLFEIRTNP--ENYQLILSYAD
|. .. ||.|||...|  .. . |   |. .| | |.     .  ..   . .....|.| .|.| |   .| |   . |...  ..   |. .|. | .
YCLNHCLGKGSFGVKVYKGRNKKTNTQNQYVACKMIDKKKMNKKKNEQEGQYMWQLLKNEIQIMKKLKELKHPNHHIVKLYDWFETSNHNNIYIIMEYCN

GGDLFEKINQHGGLGSDE----------AHRYFKQLIDGLRFIHEEGVTHRDIKPENLLLTK------------SGILKIADFGFATMHRFNG-AEQMLN
||||.. |.....|.  .          |  .|||.. |....|.... ||||||.|.|...            .|.||||||||| .   |. ..||. 
GGDLEQYIKKNKKLPE-TEEKKRLSEQEAIQFFKQICNGFKELHKHNIIHRDIKPQNILIHNGQPKTDSKKVHPNGVLKIADFGFAKHVDNNNMEQQMCQ

AYC------GSPPYIAPEVLT----GIDYRGPAVDIWSAGVVLIAMIAGAVP---W
 ..      |.| | ||..|     ...|    .|||| |...  |. | .|   |
TCVNEKRIKGTPLYMAPQILQGQGEQKPYYDYKCDIWSLGCIFYEMLYGKYPFFSW
Kinase R02C2.1.AA QIK 18-221 33 2e-46 160.52 In-house 1-217 (272) Show / Hide 
Range on Protein: 18-221
Range on HMM: 1-217/272
Sequence Identity: 33% (74 aa)

YEFIENLGEGSFAEVVLVAKVGTPNKMFAMKEISIVGKDECFMESIKRECSIQKRLSKSRHLNMIHLFEIRTNPENYQLILSYADGGDLFEKINQHGG--
|.    .| | || || .|.     .  | | |     ||  .. ..||  | |.|   .| . | |...    .   ..  |. .|..|. ...||   
YDIERTIGKGNFA-VVKLARHRITKTKVAIKIIDKSQLDEENLQKCYREVQIMKML---YHPHIIKLYQVMETDDMMYIVTEYCSNGEMFDYLCKHGRKG

------------------LGSDEAHRYFKQLIDGLRFIHEEGVTHRDIKPENLLLTKSGILKIADFGFATMHRFNGAEQMLNAYCGSPPYIAPEVLTGID
                  .  .|| | |.|.. .  . |. .. |||.| ||.|| .    |||||||     .   .|.|. .|||||| |||.. |..
VKMVNSPDIGDQVLMGVPMAENEARRWFWQICSAVHYCHKRNIVHRDLKAENILLDNNMNIKIADFGFSN---WFKQGQLLMTWCGSPPYAAPEMFEGKE

YRGPAVDIWSAGVVLIAMIAGAVP
| || ||||| |||| ....|| |
YDGPKVDIWSMGVVLYVLVCGALP
Kinase R02C2.1.AA TyrKc 18-278 19 4e-10 -58.92 SMART 1-280 (280) Show / Hide 
Range on Protein: 18-278
Range on HMM: 1-280/280
Sequence Identity: 19% (60 aa)

YEFIENLGEGSFAEVVL-VAKVGTPNKMFAMKEISIVGKDECFMESIKRECSIQKRLSKS--RHLNMIHLFEIRTNP-------ENYQLILSYADGGDLF
 .... |||| | ||.. ..|      . | | .         .| . || .|   ..|   .| | . |. . | .       | . ... |...||| 
ITLGKKLGEGAFGEVYKGTWK-----IQVAVKMLKEDA-----REDFMREARI---MCKLGGHHPNIVRLYGVCTQQGRNFMYIEPLMIVMEYMPHGDLK

EKINQHGG-LGSDEAHRYFKQLIDGLRFIHEEGVTHRDIKPENLLLTKSGILKIADFGFATMHRFNGAE-------QMLNA-Y--CGS--PPY--IAPEV
. .  |.. |  .. . .  |  .| ...|. .. |||.   | |... .. ||.||| .   |. . .       ..  .    .|    |.   |||.
DYLRKHRPKLCMKDLLSFCWQIACGMEYLHSKNCIHRDLAARNCLVGENHTVKISDFGLS---RDIYDDDQQGESKDYYRKKEHKGGKTMLPIRWMAPEC

LTGIDYR--GPAVDIWSAGVVLIAMIA-GAVPWEQ-----ADHFDIFQSRYCSFRRNGRKGAWSR--------MSQQVISLLRKILLQ-AELRATISMIE
.   .|.   .. |.|| ||..  .   |. |..       . .....      .. .|              ... . .. ..     .| | | | | 
I---NYGKFTTKSDVWSFGVCMWEIFTYGQQPYPGMIQQMMSNQEVIE----YVKQGYRMPQPPNDYPMSFVCCPDEMYQIMKQCWHEDPEDRPTFSEIH

EDP
|. 
ECF
Kinase R02C2.1.AA AMPK 18-29 41 0.103138 0.93 In-house 1-12 (254) Show / Hide 
Range on Protein: 18-29
Range on HMM: 1-12/254
Sequence Identity: 41% (5 aa)

YEFIENLGEGSF
|   ...|||.|
YIIGKTIGEGTF
Kinase R02C2.1.AA QIK 250-280 37 0.273538 1.3 In-house 241-272 (272) Show / Hide 
Range on Protein: 250-280
Range on HMM: 241-272/272
Sequence Identity: 37% (12 aa)

MSQQVISLLRKIL-LQAELRATISMIEEDPWF
|||   .| |. | . .| | ||  | . .| 
MSQDCEHLIRHMLVVDPEHRYTIMQICQHRWM