Gene R02C2.2 (Nematode worm)

R02C2.2

Species: Nematode worm
Alias: R02C2.2, CE12478, aSWK037
External Links: Wormbase Link ,
Annotation: WormBase Physical Map location: V: 245675-243227, WormBase Genetic Map location: V:-19.23,

Classification

Group: CAMK
Family: CAMKL
Subfamily: CHK1

Sequence

Name Sequence Type Origin Length Description Download
R02C2.2.kin_dom Protein Kinase Domain Sugen global kinase HMM prediction 275 Kinase domain by global Sugen HMM Fasta, JSON
R02C2.2.AA Protein Genbank 484 None Fasta, JSON

Protein domain

Protein domains of R02C2.2.AA. The domains are annotated by HMM profiles from Pfam and SMART, as well as in-house data which includes HMMs of each individual kinase group, family and subfamily. Here is domain list in details, including sequence identity, significance and alignment. In particular, you can find can find the best hit kinase group/family/subfamily, which is helpful to understand the relationship between kinases.Kinase domain and best hit kinase group/family/subfamily are highlighted in red and blue. Visualized by pviz.

Usage: Zoom in selected region by dragging mouse and zoom out by double-clicking.

Show/hide domain list
Domain Protein name Domain Name Range Identity (%) Significance Score Profile Source Profile Range (length) Alignment
Kinase R02C2.2.AA CHK1 25-290 51 1.5e-186 626.03 In-house 1-276 (276) Show / Hide 
Range on Protein: 25-290
Range on HMM: 1-276/276
Sequence Identity: 51% (141 aa)

YEVLKPLGQGSFGQVALVSNRRYPEMLAALKRIVITGQD-REYIDA-IRKEITIQESL--TG-HENVIQVLGKESDAQFCYMFLEYADGGDLYEKITSGC
|||...||.|.||||.|..|.|.||...|.|.|.|.||. ....|. ||||..||..|  .| |||||...|...|..|.|.|.||||||||..||...|
YEVVQTLGEGAFGQVKLCENQRNPEEAVAMKEIHIKGQHKMCFMDNDIRKEYCIQKMLSKIGKHENVIRMMGMRMDPEFYYLFMEYADGGDLFDKIEPDC

SFSLEEAHSYFKQLVNGLKFLHCRD-VAHRDIKPENLMLTHSGKSEMR-HLKIADFGLATWYR-YKGAELIFEQRCGSVEYVAPEIYTGAQYRGPQIDIW
... .|||.|||||..|||..||.. |.|||||||||.|.......|. .||||||||||||| ..|.|.....|||...|.|||..||.|||||..|||
GMPSDEAHRYFKQLISGLKYIHCCGGVTHRDIKPENLLLDKHDSNDMPDNLKIADFGLATWYRRHDGEERMLDKRCGTPPYMAPEVCTGKQYRGPPVDIW

SAGVVLLAMLTRQLPWEFPC-MTNKRYFFWMKNR-VAHIDAWNELSCRAKKLLWKMLSPGSENRATIEEIQSSACN
|.||||.||||..|||..|. |....|..||.|. ..|...|....|||..||.|.|......|||||.|......
SCGVVLMAMLTGELPWDQPSHMDCQEYCWWMDNKHWMHWCPWSKIDCRAICLLRKILCENPNKRATIEQIEKDPWY
Kinase R02C2.2.AA CAMKL 25-290 30 2.5e-107 343.59 In-house 1-297 (297) Show / Hide 
Range on Protein: 25-290
Range on HMM: 1-297/297
Sequence Identity: 30% (93 aa)

YEVLKPLGQGSFGQVALVSNRRYPEMLAALKRIVITGQD-REYIDA------------IRKEITIQESL-TG-HENVIQVLGKESDAQF------CYMFL
|...| ||.||||.| |  ..|...   | | | . .   ......            ||.|| |...| .| |.|.|. .    . ..      .|...
YRIGKTLGKGSFGKVKLATHIRTTGEKVAIKIIDKKKIWNDPWMKKNKCGQKHESDMRIRREIQIMKMLNIGKHPNIIKLYEVIETPEHDIETKKIYLVM

EYADGGD--LYEKI--TSGCS--FSLEEAHSYFKQLVNGLKFLHCRDVAHRDIKPENLMLTHSGKSEMRHLKIADFGLATWYR-Y-KGAELIFEQRCGSV
||..||.  |...|    ..   .. .||. ||.|.| .....| ....||||||||..|...|..    .||.|||....|| . .| .  .. .||| 
EYCSGGEMDLFDYIVKHGHRRGRMPEHEARRYFRQIVSAVNYCHSHGIVHRDIKPENILLDENGNN---NIKIIDFGFSNMYRPCIFGPGQKLKTFCGSP

EYVAPEIYTG--AQYRGPQIDIWSAGVVLLAMLTRQLPWEFPCM-----TNKRYFFWMKNRVAHID-AWNELSCRAKKLLWKMLSPGSENRATIEEIQSS
.| ||||. |   .|.||..||||.||.| ||.. .||.. ...     .|. |..|....  . .  |...| ... |. ||| .  | |.||..| . 
PYMAPEIFQGNNKPYDGPKVDIWSCGVILYAMVCGYLPFDDDTYNKQGKDNI-YLYWKIMCG-YYPPIWYHVS-DCRDLIRKMLQVNPEKRPTIHQIMNH

ACN
   
PWM
Kinase R02C2.2.AA CAMK 30-290 21 4.6e-79 254.24 In-house 1-425 (425) Show / Hide 
Range on Protein: 30-290
Range on HMM: 1-425/425
Sequence Identity: 21% (91 aa)

PLGQGSFGQVALVSNRRYPE-----------MLAALKRIVITGQD-------------------------REYIDA-IRKEITIQESLTG------HENV
 ||.||||.| |. ... .               | | |  .  .                         |..  . .|.|| |  .| |      |.|.
TLGRGSFGKVKLCIHKNTTGKERVHHIYTNGQKVAIKIIDKKKLKDKQNQDYSNCYKIDKSKCKHRYCWRRPKDRKNVRREIEIMKKLQGIGNKLDHPNI

IQVLG---------------KESD-----AQFCYMFL---EYADGG----DLYEKITSGCS---------------FSLEEAHSYFKQLVNGLKFLHCRD
|. .                  |.      ...||..   ||..||    ||...|..  .               |. .||. ||.|.. .....| ..
IKLYEVYEDPHYFKNTNDYET-SKQVFTKDKHMYMVMEIMEYCSGGELFDDLFDYIVEHGCYGEEFDQFDIVERGRFTEREARRYFRQICSAVHYCHSHN

VAHRDIKPENLMLTHSGKSEM------------RHLKIADFGLATWYR----------YKGAELIFEQ-------------RCGSVEYVA-PEIYTG---
..|||.||||..|.......               .||.|||.|. ..          |||.| . ..             .||. ||.| ||.  |   
IVHRDLKPENILLDDNNDDSDPVEHDEIFDWNNNNIKIIDFGFANKFDPGENNFMCSDYKGGE-M-HNQWTTPTEGQKMKTFCGTPEYMAAPEVLNGKGH

----------AQYRGPQIDIWSAGVVLLAMLTRQLPWEFPCMTNKR---------YFFWMKNRVAHID-AWNE-----------------------LSCR
           .| ||..|.||.||.| .||.  .|.. .|  . .         |  . | . .  |  . .                       .|  
CNMQNATDEEKPYYGPKCDMWSCGVILYIMLCGYPPFYGDCDNEICEDEWIGMNDYELFEKIMKGKYDFPPPYFSPISCNYGPEWWDDISDEFHHFVSQE

AKKLLWKMLSPGSENRATIEEIQSSACN
.| |. ||| .  |.|.|||.. .    
CKDLIRKMLQVDPEKRMTIEQCLNHPWM
Kinase R02C2.2.AA S_TKc 25-293 27 6.4e-70 239.51 SMART 1-231 (231) Show / Hide 
Range on Protein: 25-293
Range on HMM: 1-231/231
Sequence Identity: 27% (77 aa)

YEVLKPLGQGSFGQVALVSNRRYPEMLAALKRIVITGQDREYIDAIRKEITIQESLTGHENVIQVLGKESDAQFCYMFLEYADG--GDLYEKITSGCS--
||.|...|.|.||.| .. ...    . |.|.|          . ||.|| | ..  .|.|... ..   | .. ||..||.||  |||.. | .  .  
YEILRKIGKGAFGKVYKCRHKK-TGRIVAIKIIK---------EHIRREIQILKK--HHPNIVKLYDVFQD-DHLYMVMEYCDGDLGDLFDYIKKRGRHG

----FSLEEAHSYFKQLVNGLKFLHCRDVAHRDIKPENLMLTHSGKSEMRHLKIADFGLATWYRYKGAELIFEQRCGSVEYVAPEIYTGAQYRGPQIDIW
    |.  .| .|..|....|...| . . |||.||||..|..       |.||.|||||. .            ||. .|.|||.    .| .. .|.|
LRFPFPE-HARFYMYQICCALEYCHSHGIIHRDLKPENILLDE-------HIKICDFGLARQL---------TTFCGTPWYMAPEVL---GYGKCKCDWW

SAGVVLLAMLTRQLPWEFPCMTNKRYFFWMKNRVAHIDAWNELSCRAKKLLWKMLSPGSENRATIEEIQS----SACNRLL
| |..|  ||... |..    . .. |  ..            |  || .. |.|    |.| |. |.       .|   .
SCGCILYEMLCGYPPFP----QMQMMFKKIG------------SPEAKDFIRKCLQKDPEKRPTA-EALQDEWDIKCHPWF
Kinase R02C2.2.AA Pkinase 25-232 31 1.4e-59 209.1 Pfam 1-212 (293) Show / Hide 
Range on Protein: 25-232
Range on HMM: 1-212/293
Sequence Identity: 31% (69 aa)

YEVLKPLGQGSFGQVALVSNRRYPEMLAALKRIVITGQDREYIDAIRK--EITIQESLTGHENVIQVLGKESDAQFCYMFLEYADGG----DLYEKIT--
|......|.||||.| .  .. ... . |.|.|   ... .   . |.  || |  .| .|.|... ..   | . .|| .||..||    ||.. |.  
YHIGRKIGSGSFGCVYKCHHKGTGK-IVAVKIIKKRHEKSWKDQTHRRLSEIQIMKRL-NHPNIVRLYDWFEDKDHIYMVMEYCEGGLYVMDLFDYISTW

SGCSF--SLEEAHSYFKQLVNGLKFLHCRDVAHRDIKPENLMLTHSGKSEMRHLKIADFGLATWYRYKGAELIFEQRCGSVEYVAPEIYTGAQYRGPQID
....|  | .|. .|..|.. ||...| . . |||.||||... . |  .  ..||.|||||  ..       .  .||. .|.|||.  |.|| || .|
RHGCFYFSEWECKFYMYQILRGLEYCHSMGIIHRDLKPENILIDNNGHIDA-CVKICDFGLAKQFD-Y-NNS-MTTFCGTPWYMAPEVIRGGQYYGPKVD

IWSAGVVLLAMLTRQLPW
.||.|..|  ||....|.
MWSCGCILYEMLCGRPPF
Kinase R02C2.2.AA Ciliate-E2 25-284 21 8.2e-53 179.62 In-house 1-359 (365) Show / Hide 
Range on Protein: 25-284
Range on HMM: 1-359/365
Sequence Identity: 21% (83 aa)

YEVLKPLGQGSFGQVALVSNRRYPEMLA-----------------ALKRIVITGQDREYIDAIRKEITIQE---------------SLTGHENVIQVL-G
|...| .|||.||.| ...... ... |                 . | . .  .    | .| .|| |                 ..  | |.|.    
YKFIKKIGQGNFGSVYKCKVWKVQKQFAIKIIDQKQQRQQMQEKVKIKIYAMKIMKKNQIEQIKQEIHIMREINCFYKKINEKNILEQLNHPNIIKMYEC

KES-DAQFCYMFLEYADGGDLYEKITSGC-----------SFSLEEAHSYFKQLVN---------------GLKFLHCRD-VAHRDIKPENLMLTHSGKS
 .. | . .|. .||..||||.. | . .           .|...|.  ..||...               .|..|| .  . ||||||||...      
FQEKDDNNIYLVMEYCQGGDLFDYIKNNKKKRNHEIEKDKYFTEKEIKYIMKQILQGFKTKAEFYIACIILALEYLHSKNNIIHRDIKPENILF------

EMRHLKIADFGLAT----------------WYRYKG--------------AELIFEQRCGSVEYVAPEIYTGAQY--------RGPQIDIWSAGVVLLAM
    .||.||||..                || . .               . .| . ||. .|.||||. | .|         . ..||||.||.|  |
----IKIIDFGLSKKYDDDNQNRTHKQQCKWYMF-KNDTSRTPGYMDQIIQQNMFNTICGTPGYMAPEILNGKKYDNQQKQKGYDYKCDIWSLGVILYEM

LTRQLPWEFPCMTNKRYFFWMKNRVAHID----------------AWNELSCRAKKLLWK----MLSPGSENRAT-IEEI
|. ..|.          .   |.    ..                 |...|  .| |. |    ||    |.| | .|.|
LFGKPPF----------QQQIKQCKIDFPCPEWQKDTQCIQCKWKSWKKWSQECKDLIKKFGKRMLQKDPEKRITGWEQI
Kinase R02C2.2.AA MARK 25-284 30 3.1e-43 139.3 In-house 1-256 (262) Show / Hide 
Range on Protein: 25-284
Range on HMM: 1-256/262
Sequence Identity: 30% (81 aa)

YEVLKPLGQGSFGQVALVSNRRYPEMLAALKRIVITGQDR-EYIDAIRKEITIQESLTGHENVIQVLGKES--DAQF-CYMFLEYADGGDLYEKITSG--
|..|| .|.||...| |. ....     |.| .  .  .. . .  .. || |  .|  |.|.|. .      . |   |. .||| ||.||. | .   
YKMLKTIGHGSYAKVKLACHKHTG-RKVAIKIYEKFKLNDPQWMKNVMREIEIMKKLD-HPNIIKLFHVIEQDTEQHQIYLIMEYASGGELYDYIKAHPN

CSFSLEEAHSYFKQLVNGLKFLHCRDVAHRDIKPENLMLTHSGKSEMRHLKIADFGLATWY--RYKGAELIFEQRCGSVEYVAPEIYTGAQYRGPQIDIW
   . |||. .|.|.| .....| ....||||||||... . |.   .  ||.|||...      |      .  ||. .| ||||  .  | || .|||
GRLHEEEARRIFRQIVSAVNYCHSKNIVHRDIKPENILIDENGN---HNIKIIDFGFSICIPPGQK-----LNTFCGTPPYMAPEIFLKKPYDGPKVDIW

SAGVVLLAMLTRQLPWEFPCMTNKRYFFWMKNRVAHIDAWNELSCRAKKLLWKMLSPGSENRATIEEI
| |||| .|.. ..|..  ....|  .. . . . .|     .|  ...|. ..| .  | |.|||||
SLGVVLYFMVCGYFPFDGDTQDYKELYKKILRGKYDIPCH--VSKECRNLIQRLLTVNPEERPTIEEI
Kinase R02C2.2.AA AMPK 100-233 39 2.7e-40 117.37 In-house 76-201 (254) Show / Hide 
Range on Protein: 100-233
Range on HMM: 76-201/254
Sequence Identity: 39% (53 aa)

YMFLEYADGGDLYEKITSGCSFSLEEAHSYFKQLVNGLKFLHCRDVAHRDIKPENLMLTHSGKSEMRHLKIADFGLATWYRYKGAELIFEQRCGSVEYVA
.|..||. ||.|.. |..    . .||  .|.| ..|.  .|   ..||| ||||| |      .  ..||.||||   .  .|  |     |||  | |
FMVMEYVSGGELFDYIVKHGRLQEREACRFFQQIISGVEYCHRHMIVHRDLKPENLLL-----DHNKNIKIVDFGLSNMMK-DGEFL--KTACGSPCYAA

PEIYTGAQYRGPQIDIWSAGVVLLAMLTRQLPWE
||. .|  | ||..|||| ||.| ||| . || .
PEMISGKLYCGPEVDIWSCGVILYAMLCGYLPFD
Kinase R02C2.2.AA Ciliate-E2-Unclassified 25-231 25 3e-40 137.33 In-house 1-269 (352) Show / Hide 
Range on Protein: 25-231
Range on HMM: 1-269/352
Sequence Identity: 25% (68 aa)

YEVLKPLGQGSFGQVALV---SNRRYPEMLAALKRIVITGQDREYIDAIRKEITIQESL------------------TGHENVIQVLGKESDAQFCYMFL
|...| .|||.||.| ..   ..  |  |  . | ...  .  .. | |  |... ...                    |....  .  . | | .|. .
YKIIKQIGQGGFGKVYKCQHKKQKQYYAMKYMKKIQIYKQKQIMNKDEIMNEMKEMNNKKKYHQRKYNKIMQQILLNHPHPFIVKMFYCFQDKQNIYIVM

EYADGGDLYEKITS-----------------GCSFSLEEAH-----SYFKQLVNGLKFLHCRD-VAHRDIKPENLMLTHSGKSEMRHLKIADFGLATWYR
||..|||| . |..                 .. |. ..|       ||.|...||..||    . ||||||||.... .||    ..||.|||..  | 
EYCEGGDLWQYIKKRKKQKQKGNDLFHNMKQRKIFTEQQAKYKKAKFYFAQILQGLEYLHHKNNIIHRDIKPENILFDNNGK--NYYIKIIDFGISKKYQ

Y----KGAEL----------IFEQRCGSVEYV----APEIYTGAQYRGP---QIDIWSAGVVLLAMLTRQLP
.    .  .           .. ..||. .|     |||.. | .| ..   ..|||| ||.| .||. ..|
QNNNCD-TNQQQKMQIWKQQMMWTFCGTPNYMPQYTAPEVLQGQNYDHSKAYKCDIWSLGVILYEMLFGYYP
Kinase R02C2.2.AA CAMK-Unique 25-227 20 8.3e-40 128.96 In-house 1-288 (363) Show / Hide 
Range on Protein: 25-227
Range on HMM: 1-288/363
Sequence Identity: 20% (60 aa)

YEVLKPLGQGSFGQVALVSNRRYPEMLAALKRIVITGQDREYIDA------------------IRKEITIQESLTGHENVIQVLGK----ESDAQ-----
|. ....|.|.|| |  . .|  .  . | |..   .. ..  ..                   ..|. |  .. .|.| |....       |..     
YKMHRIIGHGNFGHVYECMDRETG-KKWACKMVKKQTHGNKKQKQQRNFDLRYKITEKRRDMKLKREHQIWKMV-DHPNIIKLYDWNNPIFCDRKYPLCD

----------FCYMFLEYADGGDLYEKITS--------------------GCSFSL--EEAHSYFKQLVNGLKFLHCRDVAHRDIKPENLMLTHSGK---
           .|...||..||||...| .                     ..||    .. ... .|.  ....|  |. |||.|.||.|.  |.|   
LIIKTPRALPYMYIVMEYCQGGDLFDWIQKWDEFYFNFIIKFDFNILKRCQGHFSERCWDTCFIMQCLLSAVAYMHSQDIVHRDLKLENIMVCYSFKDNN

--------SEMRHLKIADFGLATWYRYKGAELIFEQRCGSVEYVAP--------------EIYTGAQYRGPQI----DIWSAGVVLLAMLT
            |.|..||||.. |. . .. .   .||. .|.||              |.  .  | . |     |||| ||..  ||.
HHRDFPYDWSNWHIKLCDFGLCCHYNHNKMCHMMQTMCGTPCYMAPEIVFCKNYQEMTRDEVINMQCY-DQQCSPASDIWSLGVIMYYMLC
Kinase R02C2.2.AA ULK 25-234 24 1.7e-36 124.97 In-house 1-260 (329) Show / Hide 
Range on Protein: 25-234
Range on HMM: 1-260/329
Sequence Identity: 24% (65 aa)

YEVLKPLGQGSFGQVALV--SNRRYPEMLAALKRIVITG---QDREY--------IDAIRKEITIQESLT---GHEN----VIQVLGKESDAQF--CYMF
|.. . ||.||||.|      ..  .   . .  . .     .....        .. ...|| |.  |    .|.|    ... .    ....  .|..
YCLNHCLGKGSFGKVYKGRNKKTK-D-YVNEKVACKMIDKQKMNQKNNEQEGQYMWQLLKNEIKIMKKLKSPNRHKNHHPNIVKLYDWFETSNHNNIYII

LEYADGGDLYEKIT----------SGCSFSLEEAHSYFKQLVNGLKFLHCRDVAHRDIKPENLMLTH---------SGKSEMRHLKIADFGLATWYRYK-
.|| .|||| . |            .  .| .|| ..|||..||.|.|| . . ||||||.| ...          .  .   .|||||||.|    .  
MEYCNGGDLEQYIKKNKKLPEDTEEKKRLSEQEAIQFFKQILNGFKELHKHNIIHRDIKPQNILIHNGQPKTDSKKV-HP-NGVLKIADFGFAKHVDNDN

-GAELIFEQR-----CGSVEYVAPEIYT----GAQYRGPQIDIWSAGVVLLAMLTRQLP---WEF
  ....  .      ||.  | ||.|      . .|     |||| |...  ||. . |   | |
MEQQMMMTCVNEKRLCGTPLYMAPQILQGQGEQKPYYDYKCDIWSLGCIFYEMLYGKPPFYAW-F
Kinase R02C2.2.AA ULK 25-234 26 2.8e-36 126.27 In-house 1-256 (324) Show / Hide 
Range on Protein: 25-234
Range on HMM: 1-256/324
Sequence Identity: 26% (70 aa)

YEVLKPLGQGSFG-QVALVSNRRYP--EMLAALKRIVITGQDREYID--------AIRKEITIQESLT--GHEN--VIQVLGKESDA--QFCYMFLEYAD
|.. . ||.|||| .|    | .      . | | | . ..   . .         ...|| |.  |    |.|  ... .    ..   ..|...|| .
YCLNHCLGKGSFGVKVYKGRNKKTNTQNQYVACKMIDKKKMNKKKNEQEGQYMWQLLKNEIQIMKKLKELKHPNHHIVKLYDWFETSNHNNIYIIMEYCN

GGDLYEKIT---------SGCSFSLEEAHSYFKQLVNGLKFLHCRDVAHRDIKPENLMLTH---------SGKSEMRHLKIADFGLATWYRYKGAELIFE
|||| . |           .  .| .|| ..|||..||.|.|| . . ||||||.|.....         .  .   .|||||||.|   .    .   .
GGDLEQYIKKNKKLPETEEKKRLSEQEAIQFFKQICNGFKELHKHNIIHRDIKPQNILIHNGQPKTDSKKV-HP-NGVLKIADFGFA---KHVDNNNMEQ

QRC----------GSVEYVAPEIYT----GAQYRGPQIDIWSAGVVLLAMLTRQLP---WEF
| |          |.  | ||.|      . .|     |||| |...  ||. . |   | |
QMCQTCVNEKRIKGTPLYMAPQILQGQGEQKPYYDYKCDIWSLGCIFYEMLYGKYPFFSW-F
Kinase R02C2.2.AA TyrKc 25-292 17 1.1e-10 -49.95 SMART 1-280 (280) Show / Hide 
Range on Protein: 25-292
Range on HMM: 1-280/280
Sequence Identity: 17% (55 aa)

YEVLKPLGQGSFGQVALVSNRRYPEMLAALKRIVITGQDREYIDAIRKEITIQESL-TGHENVIQVLGKESDA-------QFCYMFLEYADGGDLYEKI-
 . .| || | ||.| .   .    .  | | .         . ....|. |  .|   |.|... .|  ..        .  .. .||...||| . . 
ITLGKKLGEGAFGEVYKGTWK----IQVAVKMLKEDA-----REDFMREARIMCKLGGHHPNIVRLYGVCTQQGRNFMYIEPLMIVMEYMPHGDLKDYLR

TSGCSFSLEEAHSYFKQLVNGLKFLHCRDVAHRDIKPENLMLTHSGKSEMRHLKIADFGLATWYRYKGAE--------LIFEQR--CGS----VEYVAPE
 ..  ..... .|.  |  .|  .|| . . |||.   | .... .     . ||.||||.   |. . .         .  .   .|     .   |||
KHRPKLCMKDLLSFCWQIACGMEYLHSKNCIHRDLAARNCLVGENH-----TVKISDFGLS---RDIYDDDQQGESKDYYRKKEHKGGKTMLPIRWMAPE

IYTGAQYR--GPQIDIWSAGVVL--LAMLTRQLPWE---FPCMTNKRYFFWMKNRVAHIDAWNELSCRAK--------------KLLWKMLSPGSENRAT
     .|.   .. |.|| ||..  .  .  | ...      |.|.. . . |..       . . . .               ..  .      |.| |
CI---NYGKFTTKSDVWSFGVCMWEIFTYGQQPYPGMIQQ-MMSNQEVIEYVKQG-------YRMPQPPNDYPMSFVCCPDEMYQIMKQCWHEDPEDRPT

IEEIQSSACNRL
 .||    . ..
FSEI----HECF
Kinase R02C2.2.AA Pkinase_Tyr 83-176 23 0.003576 11.37 Pfam 63-158 (270) Show / Hide 
Range on Protein: 83-176
Range on HMM: 63-158/270
Sequence Identity: 23% (24 aa)

HENVIQVLGKES-DAQF--CYMFLEYADGGDLYEKITS----GCSFSLEEAHSYFKQLVNGLKFLHCRDVAHRDIKPENLMLTHSGKSEMRHLKIADFGL
|.|... .|  . . .    |. .||. .|||..   .    . ......  ..  |  .|. .|. .   |||.   | ..|.    .. . ||.||||
HPNIVRLYGVCTDQGEPNQIYIVMEYMPHGDLLDYLRKHREDKQPLTMKDLLQMCWQIAKGMEYLESKNCIHRDLAARNCLVTE----NN-VVKICDFGL

A
|
A
Kinase R02C2.2.AA AMPK 259-290 34 0.005992 4.66 In-house 223-254 (254) Show / Hide 
Range on Protein: 259-290
Range on HMM: 223-254/254
Sequence Identity: 34% (11 aa)

LSCRAKKLLWKMLSPGSENRATIEEIQSSACN
|| .|| |. .|| .  ..|.||..|  ..  
LSPEAKDLIKHMLQVDPMKRITIHDIRNHPWF
Kinase R02C2.2.AA AMPK 25-39 46 0.006667 4.52 In-house 1-15 (254) Show / Hide 
Range on Protein: 25-39
Range on HMM: 1-15/254
Sequence Identity: 46% (7 aa)

YEVLKPLGQGSFGQV
| . | .| |.|| |
YIIGKTIGEGTFGKV
Kinase R02C2.2.AA Pkinase_Tyr 25-39 46 0.235618 5.21 Pfam 1-15 (270) Show / Hide 
Range on Protein: 25-39
Range on HMM: 1-15/270
Sequence Identity: 46% (7 aa)

YEVLKPLGQGSFGQV
 . .| ||.|.||.|
ITFGKKLGEGAFGEV