Gene T14E8.1 (Nematode worm)

T14E8.1

Species: Nematode worm
Alias: T14E8.1, aSWK401, CE28667, T14E8.1a, T14E8.1A
External Links: Wormbase Link ,
Annotation: WormBase Genetic Map location: X:-2.83, WormBase Physical Map location: X: 6557050-6562877

Classification

Group: TK
Family: Met

Sequence

Name Sequence Type Origin Length Description Download
T14E8.1.kin_dom Protein Kinase Domain Sugen global kinase HMM prediction 305 Kinase domain by global Sugen HMM Fasta, JSON
T14E8.1.AA Protein Genbank 1086 None Fasta, JSON

Protein domain

Protein domains of T14E8.1.AA. The domains are annotated by HMM profiles from Pfam and SMART, as well as in-house data which includes HMMs of each individual kinase group, family and subfamily. Here is domain list in details, including sequence identity, significance and alignment. In particular, you can find can find the best hit kinase group/family/subfamily, which is helpful to understand the relationship between kinases.Kinase domain and best hit kinase group/family/subfamily are highlighted in red and blue. Visualized by pviz.

Usage: Zoom in selected region by dragging mouse and zoom out by double-clicking.

Show/hide domain list
Domain Protein name Domain Name Range Identity (%) Significance Score Profile Source Profile Range (length) Alignment
Kinase T14E8.1.AA Met 736-987 50 9.80000000001e-195 644.27 In-house 1-271 (271) Show / Hide 
Range on Protein: 736-987
Range on HMM: 1-271/271
Sequence Identity: 50% (137 aa)

DKLDPIGQGHYGVVYKAMYSPSKSLEEKVVCKYLK------EGKISEFYEEARTMSEFDHPNILKLIGVALDDSSHLPIIITEYMAKGDLKSFIENVENT
...|.|||||.|.||..||......|....||.|.      ...||.|..|...|..|||||.|.|||..||...|.|.....||..||||.||.|..|.
HFDDVIGQGHFGCVYHGMYHDNDGNEHHCACKSLHGERITDIQHISQFLREGIMMKHFDHPNVLSLIGICLDPEGHMPWVVLPYMKHGDLKTFIRNPQNN

IKMRDLFEFAFDIAKGMNYMHSKKFIHRDLACRNCLLDEHLRVKIADFGLCRKVDIETELYVQMHERD---LPVRWFPPEISE---------QG-FGITS
...|||.||....||||.||.|.||.|||||||||.||||..||.|||||||..|...|.|.|||...   |||.|..||...         .  |...|
PCVRDLIEFCHQVAKGMMYMASQKFVHRDLACRNCMLDEHFTVKVADFGLCRDMDYDKEYYSQMHHTHPARLPVKWMAPECLQQGVCLGCPTYRQFTTKS

DIWSFGVVIWELFTRGSTPYSNMASWILILPWLKESETNRLRKPPYCPEKLYTDVMLACWKANPAERPQFS
|.||||||.|||.|||..||.....|..|..||...||.||..|.|||..|||||||.||.|||..|||||
DVWSFGVVMWELMTRGAPPYPHVDNWFDITHWLHQGETRRLPQPEYCPDHLYTDVMLCCWHANPEDRPQFS
Kinase T14E8.1.AA TyrKc 735-993 35 4.90000000001e-116 392.72 SMART 1-280 (280) Show / Hide 
Range on Protein: 735-993
Range on HMM: 1-280/280
Sequence Identity: 35% (102 aa)

VDKLDPIGQGHYGVVYKAMYSPSKSLEEKVVCKYLKEGKISEFYEEARTMSEF--DHPNILKLIGVALDD-----SSHLPIIITEYMAKGDLKSFIENVE
. ... .| |..|.|||....      ..|  | |||... .|..||| |...  .||||..|.||....     ... . |..|||..||||... . .
ITLGKKLGEGAFGEVYKGTWK------IQVAVKMLKEDAREDFMREARIMCKLGGHHPNIVRLYGVCTQQGRNFMYIEPLMIVMEYMPHGDLKDYLRKHR

NTIKMRDLFEFAFDIAKGMNYMHSKKFIHRDLACRNCLLDEHLRVKIADFGLCRKVDIE------TELYVQM---HERD-LPVRWFPPEISEQG-FGITS
....|.|| .|...||.||.| |||..||||||.||||..| ..|||.||||.|... .      .. |...   .... ||.|| .||    | | . |
PKLCMKDLLSFCWQIACGMEYLHSKNCIHRDLAARNCLVGENHTVKISDFGLSRDIYDDDQQGESKDYYRKKEHKGGKTMLPIRWMAPECINYGKFTTKS

DIWSFGVVIWELFTRGSTPYSNM----ASWILILPWLKESETNRLRKPPY--------CPEKLYTDVMLACWKANPAERPQFSDLVTII
|.|||||..||.||.| .||..|     |.. .. ..|.   .|...||.        ||...|. .|. ||...|..|| ||... ..
DVWSFGVCMWEIFTYGQQPYPGMIQQMMSNQEVIEYVKQG--YRMPQPPNDYPMSFVCCPDEMYQ-IMKQCWHEDPEDRPTFSEIHECF
Kinase T14E8.1.AA Pkinase_Tyr 735-993 36 3.3e-109 370.48 Pfam 1-270 (270) Show / Hide 
Range on Protein: 735-993
Range on HMM: 1-270/270
Sequence Identity: 36% (99 aa)

VDKLDPIGQGHYGVVYKAMYS-PSKSLEEKVVCKYLKEGKISE------FYEEARTMSEF-DHPNILKLIGVALDDSSH-LPIIITEYMAKGDLKSFIEN
. ..  .|.|..|.|||. .    .. . .|  | ||||  .|      | .||..|... .||||..|.|| .|.. .  ..|..|||..|||...  .
ITFGKKLGEGAFGEVYKGTWKGDPDNTKIPVAVKMLKEGAMHEQNCREDFMREAKIMKQLGHHPNIVRLYGVCTDQGEPNQIYIVMEYMPHGDLLDYLRK

V---ENTIKMRDLFEFAFDIAKGMNYMHSKKFIHRDLACRNCLLDEHLRVKIADFGLCRKVDIETELY-VQMHERDLPVRWFPPE-ISEQGFGITSDIWS
    .. ..| || .....|||||.| .||..||||||.||||..| . |||.||||.| .  ... | .. .. .||..| .|| |..  | . ||.||
HREDKQPLTMKDLLQMCWQIAKGMEYLESKNCIHRDLAARNCLVTENNVVKICDFGLARDI-YNDDYYYRKRGGGKLPIKWMAPECINYGKFTTKSDVWS

FGVVIWELFTRGSTP-YSNMASWILILPWL-KESETNRLRKPPYCPEKLYTDVMLACWKANPAERPQFSDLVTII
|||..||.||.| .| | .| |   .. .. ..   .|. .|..||...|.  |. ||...|..|| ||... ..
FGVLMWEIFTYGEQPTYPGM-SNEEVYEYIYED--GYRMPCPENCPDEIYDL-MKQCWHYDPEDRPTFSEIHEQL
Kinase T14E8.1.AA TK 735-993 20 8.5e-95 318.21 In-house 1-486 (486) Show / Hide 
Range on Protein: 735-993
Range on HMM: 1-486/486
Sequence Identity: 20% (98 aa)

VDKLDPIGQGHYG---VVYKAMYSP----------------------SKSLEEKVVCKYLK---EGKISEFYE--------------EARTMSEFD----
.  .. .|.|..|   .|||... .                      ..  ...|  | ||   .    || .              ||. |. ..    
ITLGKKLGEGQFGSFGEVYKGEWRGRNPWNGKRFPCHMTVTLKCKNGKEGGKTPVAVKMLKEGDAMSQEEFFDEEMHDRDGGEDFLEEAEEMKMMCHSLG

-HPNILKLIGVALDDSS----------HLPIIITEYMAKGD----LKSFIENVENT--------------------------------------------
 ||||..|.|| ... .          . ..|..|||..||    |...  .  ..                                            
HHPNIVRLYGVCTQGEPKPCFEVVVHQEPWMIVMEYMPHGDMDGSLRDYLRKCRPKFQHEQDCPDNQHNKYPPSKLHHCMKGDITYSHESNSPCPEEQDY

-------------------------------IKMRDLFEFAFDIAKGMNYMHSK------KFIHRDLACRNCLLDEHLR-----------VKIADFG---
                               . |..|  ....||.|| |.|||      .|.|||||.||||..|...           .||||||   
DDDLIKDHPPPLTTKDLLQMAWQWCLTCKHQLTMHQLL-MCWQIACGMEYLHSKNCEFIQNFVHRDLAARNCLVGENNVCKWHFDGCGPVCKIADFGLSR

-----LCRKVDIETELYVQM-----------------------HERDLPVRWFPPEISEQG----------FGITSDIWSFGVVIWELFTRGSTPYSNMA
     |.|... ... |..                        . . ||.|| .||  . .          | . ||.|||||..||.||.| .||  . 
QGSGVLARDIYSDDDYYRKSSYGTGRPMWPFEDDPWQDYYRQQSGGKLPIRWMAPECLNDRVFSEAEKYGKFTTKSDVWSFGVLMWEIFTYGQEPYYGGM

SW---------ILILPWLKE------------SETNRLRKPPYCPE-------------KLYTDVMLACWKANPAERPQFSDLVTII
|            ..  |..             . .|. .||.||.             ..| |.|. ||...|..|| ||.|.  .
SNQDVWKDGDNQEVMEYLRRGGRLCRSGLNEVGYRMRMPQPPHCPDWMRYRMHPPHCPPEEYYDLMQQCWHYDPEDRPTFSQLHEQL
Kinase T14E8.1.AA UTK 735-993 33 3.7e-84 285.91 In-house 1-296 (296) Show / Hide 
Range on Protein: 735-993
Range on HMM: 1-296/296
Sequence Identity: 33% (100 aa)

VDKLDPIGQGHYGVVYKAMYSPSKSLEEKVVCKYLKEG-------KIS---EFYEEAR---TMSEFD-HPNILKLIGVALDDSSHLPIIITEYMAKGDLK
|  ....|||..|.|.||.. . . ......... .         .     .| ||||    |. |. |||.|.|.|| ....   ..|.||||..||| 
VQLGRQLGQGAFGEVHKARFTQCSEHMYEMDVAVKVCQHHADAQQEPEPYPDFMEEARELQMMKQFHWHPNVLRLVGVCTQEEP--WMIVTEYMENGDLR

SFIENVENTIK-------MRDLFEFAFDIAKGMNYMHSKKFIHRDLACRNCLLDEH-------LRVKIADFG---LCRKVDI--------ETELYVQMHE
|.  .   |         .... ..| ||| ||.|.||..|.|||||.||||...|       . .||||||   ..| |          |...| . | 
SYLRRHRPTPPACPHWLTLHQRLCMAWDIARGMQYLHSCGFVHRDLAARNCLVHMHRMMWHCMMVCKIADFGRGGMSRRVNTFHFSNRYWESYYYMAQHQ

RDLPVRWFPPEISEQG--FGITSDIWSFGVVIWELFTRGSTPYSNMASWILILPWLKESETNRLRKPPYCPEKLYTDVMLACWKANPAERPQFSDLVTII
. .|.||  ||.  ..  | . ||.|||||| ||..|.|..|| .|.   ...  .. .   |...|. ||. .| ..|..||...|.||| | |||  .
DRWPIRWMAPEALTHHTRFTTKSDVWSFGVVCWEIWTWGRLPYPGMSNMQVWHQVCNGGR-YRMPCPWDCPHPVY-RLMHRCWHYDPQERPDFEDLVQQM
Kinase T14E8.1.AA Fer 735-994 29 3.6e-67 227.8 In-house 1-283 (283) Show / Hide 
Range on Protein: 735-994
Range on HMM: 1-283/283
Sequence Identity: 29% (86 aa)

VDKLDPIGQGHYGVVYKA-----MYSPSKSLEEKVVCKYLKE-GK------ISEFYEEARTMSE-FDHPNILKLIGVALDDSSHLPI-IITEYMAKGDLK
|.  . .| |..| |||.     .. . ..  .|| .|  |  .       | ||  ||| |   .||||. |..||. |.    || |. |..  |.|.
VTLGKKLGEGAFGEVYKGRRTLKCKKGKWHVVNKVAVKVKKCKCEDATKEQIKEFMHEARIMRNNYDHPNVVKFYGVCVDEQ---PIMIVMEFCNGGSLD

SFIENVEN-TIKMRDLFEFAFDIAKGMNYMHSKKFIHRDLACRNCLLDE-HLRVK--IADFGLCRKVDIETELYVQM-HERDLPVRWFPPEISEQGFGIT
|..   .| |.............|.||.|.|||. ||||.| ||||...  . .|  |.|||..|. . ... |     .. .|.|| .||  . |.  .
SYLKKNKNKTVSDNEKIRMCYQAACGMEYLHSKNCIHRDIAARNCLYHKDKVKKKCKISDFGMSRQCSDYGYDYKMKEKACKVPIRWLAPETWQTGI-YS

--SDIWSFGVVIWELFTRGSTPYSN------MASWILILPWLKESETNRLRKPPYCPEKLYTDVMLACWKANPAERPQFSDLVTIIP
  .|.|||||..|| ||.| .|| .      |. .   .   .. . .... |. .|. ..  .|  ||...| .|| ..... .. 
PKTDVWSFGVMCWEIFTNGAEPYPGQPHGMKMTNVKKQARKWIIKKGYMMPMPNHMPPEIMQIMMKQCWQKDPEDRPTMKEICQKLK
Kinase T14E8.1.AA TK-Unique 735-993 29 4.2e-67 229.24 In-house 1-294 (294) Show / Hide 
Range on Protein: 735-993
Range on HMM: 1-294/294
Sequence Identity: 29% (89 aa)

VDKLDPIGQGHYGVVYKAMYSPSKSLEEKVVCKYLKEGK-------ISEFYEEARTMSEFD-HPNILKLIGVALDDSSHLPIIITEYMAKGDLKSFIENV
.  .| ||.| .| |....... .  ..| .| ..|  |        ..|  |.. |.| . ||||....|.  ...   . || ||...|.| ... . 
LEVGDVIGEGAFGQVWRGEVWGIWKHWDKQKCVAVKMLKDNATDTDKQDFLKEIQMMKELGDHPNIVQCLGCCTKSD-EPWMIIMEYCPCGNLQHYLRTC

ENT-------------------------IKMRDLFEFAFDIAKGMNYMHS--KKFIHRDLACRNCLLDEHLRVKIADFGLCRKVDIETELYVQM-HERDL
  .                         |...||. ||..||.||.|..|  ||..||||. ||.|| |....||.|||. |.|.  .. |. |  .  .
RPAMRQHQTYGNLKFDFHHMPDKPRTEPISPKDLYHFAWQIACGMEYLASQRKKIVHRDLCARNVLLTEDKVCKICDFGMARDVYT-NGVYSMMCSQGRI

PVRWFPPEI-S--EQGF-GITSDIWSFGVVIWELFTRGSTPYSNMASWILILPWLKESETNRLRKPPYC-PEKLYTDVMLACWKANPAERPQFSDLVTII
|.|| .||. .  .. .  . ||.|||||..||.|| |..||..| .   |.  ...    |. .|..| .. .|  .|  ||. .| ||| |.... ..
PIRWMAPESLKCYHGMYHTTKSDVWSFGVLMWEIFTLGACPYPGMPWKD-IMECIRDGY--RMPQPEHCCSHEMYN-LMKSCWQWEPEERPSFRQIKHRL
Kinase T14E8.1.AA Src 735-993 33 2.2e-66 224.51 In-house 1-255 (255) Show / Hide 
Range on Protein: 735-993
Range on HMM: 1-255/255
Sequence Identity: 33% (88 aa)

VDKLDPIGQGHYGVVYKAMYSPSKSLEEKVVCKYLKEGKIS--EFYEEARTMSEFDHPNILKLIGVALDDSSHLPI-IITEYMAKGDLKSFIE--NVENT
.  .. .|||..| |.....  .     ||  | ||.|  |   | .|| .| ...|.....|  |  ..    || |.||||..| |  .      . .
IKLCRKLGQGQFGEVWMGYWNGNT----KVAVKTLKPGTMSPEAFLQEAQIMKKLRHEKLVQLYAVCSQEE---PIYIVTEYMSHGSLLDYLKKDGEGRH

IKMRDLFEFAFDIAKGMNYMHSKKFIHRDLACRNCLLDEHLRVKIADFGLCRKVDIETELYVQMHERDLPVRWFPPE-ISEQGFGITSDIWSFGVVIWEL
.....| ..|  .|.||.|. |...|||||| || | .|.. .|.||||| | .. . . |.  |.  .|..|  || |... | | || ||||. ..|.
LHLPQLIDMAAQVAEGMAYLESMNYIHRDLAARNVLVGENNVCKVADFGLARLIKEDDDEYCARHGAKFPIKWTAPEAINYGRFTIKSDVWSFGILLTEI

FTRGSTPYSNMASWILILPWLKESETNRLRKPPYCPEKLYTDVMLACWKANPAERPQFSDLVTII
.|.| .||  |     .    . .   |. .|. ||..|| ..|| ||.. | .|| |  |    
VTYGRVPYPGMTNHEVL---QQVERGYRMPCPHNCPDELYEQIMLQCWHKDPEQRPTFEYLQWFL
Kinase T14E8.1.AA Axl 733-991 35 7.8e-60 205.09 In-house 1-267 (267) Show / Hide 
Range on Protein: 733-991
Range on HMM: 1-267/267
Sequence Identity: 35% (98 aa)

LRVDKLDPIGQGHYGVVYKAMYSPSKSLEEKVVCKYLK-----EGKISEFYEEARTMSEFDHPNILKLIGVALDDSS----HLPIIITEYMAKGDLKSF-
. . |.  .|.| .| |  .          ||  | .|     .  | ||  ||  | ||||||...||||..  |.      |..|  .|  ||| .| 
FVLGKM--LGEGEFGSVMEGQLKQEDGSFVKVAVKMMKIDICTQSEIEEFLSEAACMKEFDHPNVMRLIGVCIQMSERQRIPKPMVILPFMKHGDLHTFL

----IENVENTIKMRDLFEFAFDIAKGMNYMHSKKFIHRDLACRNCLLDEHLRVKIADFGLCRKVDIETELYVQMHERDLPVRWFPPE-ISEQGFGITSD
    ...    ...  |  |  ||| || |. ...||||||| |||.| | . | .||||| .|.  . . | |     .||.|   | . .. .   ||
LYSRLGDQPFYLPLQMLVKFMVDIACGMEYLSNRNFIHRDLAARNCMLREDMTVCVADFGLSKKI-YSGDYYRQGCIAKMPVKWIAIESLADRVYTSKSD

IWSFGVVIWELFTRGSTPYSNMASWILILPWLKESETNRLRKPPYCPEKLYTDVMLACWKANPAERPQFSDLVT
.|.||| .||. ||| |||. .     .  .|   . .||..|. | ..|| |.|  ||.|.| .|| || |  
VWAFGVTMWEIMTRGQTPYPGVEN-HEMYDYLI--HGHRLKQPEDCMDELY-DLMYQCWEADPKDRPSFSVLRE
Kinase T14E8.1.AA TKL 741-993 21 3.9e-55 189.47 In-house 1-364 (364) Show / Hide 
Range on Protein: 741-993
Range on HMM: 1-364/364
Sequence Identity: 21% (79 aa)

IGQGHYGVVYKAMYSPSKSLE-----EKVVCKYLKEGKI------------------------------SEFYEEARTMSEFDHPNILKLIGVALDDSS-
||.|..|.|||. .    . .     . |. | .|.                                  .. ||.. || ..||||....|.... .. 
IGSGGFGEVYKGKWRGWGGKCPSDTGKDVAVKKFKSHNDDEFTKNSQENNDNNNYSDMQLNDPEASWFRFFEEEEIMMMSRLRHPNIVQFMGYCCCPPCG

-------HL---PIIITEYMAKGD-LKSFIENVENTIKMRDLFEFAFDIAKGMNYMHS--------KKFIHRDLACRNCLLDEHLR--------------
       .    . |..||. .|. |  ..        .  .. .| |||.||||.||        .. |||||  .|.|.||...              
CVCMHPVGPWGQLCIVMEYCPGGSLLHYLH--------WHQRCRWALDIARGMNYLHSMNPKWCTKPPIIHRDLKSKNILVDENWTNVSNYMYNPNADWC

VKIADFGLCRKVDIETELYVQMHE-------------RDLPV---RWFPPEISEQG-----------------FGITSDIWSFGVVIWELFTRGSTPYSN
.||.||||.| .. ...   .|.              .  ..   || .||. ..                  .   .|..|||.|.||..||   ||..
CKICDFGLSRFMSQSGNMNDTMTTMMESAEHQNNRKTTMTQCGTPRWMAPEVLRGQMNYTEKVGIDEFCKGFEYSEKCDVYSFGIVLWEILTRCR-PYYD

MASWILILP-------WLKESETNRLRKP------------PYCPEKLYTDVMLACWKANPAERPQFSDLVTII
. .   |.        ..  .. .|.  |            |.||. .  . |  ||...| .|| |.... ..
YPYMPMIFQDPFEEMFMMVCDKGLRPPIPPIWQNHHKMCPCPDCPPSMK-KLMQDCWDHDPEKRPSFQEILKRL
Kinase T14E8.1.AA S_TKc 735-993 22 2.1e-48 168.07 SMART 1-231 (231) Show / Hide 
Range on Protein: 735-993
Range on HMM: 1-231/231
Sequence Identity: 22% (63 aa)

VDKLDPIGQGHYGVVYKAMYSPSKSLEEKVVCKYLKEGKISEFYEEARTMSEFDHPNILKLIGVALDDSSHLPIIITEYMAK--GDLKSFIENVEN----
 ..|..||.| .|.|||.         ..| .| .|      .. | . ... .|||| ||..|  |   .   ...||.    |||...|..       
YEILRKIGKGAFGKVYKCRHKK---TGRIVAIKIIK----EHIRREIQILKK-HHPNIVKLYDVFQD---DHLYMVMEYCDGDLGDLFDYIKKRGRHGLR

-TIKMRDLFEFAFDIAKGMNYMHSKKFIHRDLACRNCLLDEHLRVKIADFGLCRKVDIETELYVQMHERDLPVRWFPPEISEQGFGI-TSDIWSFGVVIW
  .   .   ..  |.....|.||...|||||   | ||||  ..||.||||.|..          .       . .||.   |.|   .|.||.|....
FPFPE-HARFYMYQICCALEYCHSHGIIHRDLKPENILLDE--HIKICDFGLARQL----------TTFCGTPWYMAPEVL--GYGKCKCDWWSCGCILY

ELFTRGSTPYSNMASWILILPWLKESETNRLRKPPYCPEKLYTDVMLACWKANPAERPQFSDLVT---------II
|... | .|..      ...  ..               .   | .  |.. .|..||   .. .          .
EMLC-GYPPFP---QMQMMFKKIG--------------SPEAKDFIRKCLQKDPEKRPTA-EALQDEWDIKCHPWF
Kinase T14E8.1.AA Pkinase 735-938 25 1.1e-44 159.11 Pfam 1-214 (293) Show / Hide 
Range on Protein: 735-938
Range on HMM: 1-214/293
Sequence Identity: 25% (57 aa)

VDKLDPIGQGHYGVVYKAMYSPSKSLEEKVVCKYLKEGKISEFYE-------EARTMSEFDHPNILKLIGVALDDSSHLPIIITEYMAKG----DLKSFI
  .. .||.| .|.|||..   .     .|..| .|  ....  .       |.. | ...||||..|...  | ..|.  ...||. .|    ||...|
YHIGRKIGSGSFGCVYKCHHKGTGK---IVAVKIIKKRHEKSWKDQTHRRLSEIQIMKRLNHPNIVRLYDWFED-KDHIY-MVMEYCEGGLYVMDLFDYI

E-NVENTI--KMRDLFEFAFDIAKGMNYMHSKKFIHRDLACRNCLLDEHLRV----KIADFGLCRKVDIETELYVQMHERDLPVRWFPPEI--SEQGFGI
.   ....   ....  ..  |..|..|.||...|||||   |.|.|..  .    ||.||||....|  .  .. |. .    .. .||.  . |. | 
STWRHGCFYFSEWECKFYMYQILRGLEYCHSMGIIHRDLKPENILIDNNGHIDACVKICDFGLAKQFD--Y-NNS-MTTFCGTPWYMAPEVIRGGQYYGP

TSDIWSFGVVIWELFTRGSTPYSN
 .|.||.|....|... | .|...
KVDMWSCGCILYEMLC-GRPPFPG
Kinase T14E8.1.AA RTKC 735-936 35 5.1e-44 143.1 In-house 1-208 (261) Show / Hide 
Range on Protein: 735-936
Range on HMM: 1-208/261
Sequence Identity: 35% (76 aa)

VDKLDPIGQGHYGVVYKAMYSPSK-SLEEKVVCKYLKE----GKISEFYEEARTMSEFDHPNILKLIGVALDDSSHLPI-IITEYMAKGDLKSFIENVEN
.  ||  |.|  |.||||  . ..   .  | || |..    .  .|  |||  |  |.|||. .||||    .   || .. |.. .|.|||...|   
LTLLDELGRGAFGIVYKALLEEPGGMPGYLVACKSLHHTAMDNDRQELLEEAAVMAQFEHPNVVHLIGVV---TVGKPILVVLEFCERGSLKSYLMNNP-

TIKMRDLFEFAFDIAKGMNYMHSKKFIHRDLACRNCLLDEHLRVKIADFGLCRKV--DIETEL-YVQMHERDLPVRWFPPE-ISEQGFGITSDIWSFGVV
.. .     |....| ||   ||. |||||.| || ||.  |. |.||||| |    . ...  |  .    |||||  ||   .. |   ||.|.||. 
DCTEHQKVRFCYQCASGMEHIHSFGFIHRDVAARNVLLSSDLTCKVADFGLARESPCNDDSHEAYYRSRSGNLPVRWTAPEALDDRKFSEKSDVWAFGIL

IWELFTRGSTPY
  |..|..  ||
MYEIYTKAEMPY
Kinase T14E8.1.AA Tec 738-881 36 5.7e-35 119.64 In-house 4-145 (254) Show / Hide 
Range on Protein: 738-881
Range on HMM: 4-145/254
Sequence Identity: 36% (55 aa)

LDPIGQGHYGVVYKAMYSPSKSLEEKVVCKYLKEGKISE--FYEEARTMSEFDHPNILKLIGVALDDSSHLPI-IITEYMAKGDLKSFIENVENTIKMRD
.  .|.| .|||  . .   .. . .|  | .|||  ||  | |||..| .  ||.  .| ||    | . || |.||||..| | ..    . . .   
MKELGSGQFGVVHLGKW---RH-QYDVAIKMIKEGSMSEEDFIEEAKVMMKLSHPKLVQLYGVC---SQQRPIYIVTEYMEHGCLLNYLREHKHHFQKNM

--LFEFAFDIAKGMNYMHSKKFIHRDLACRNCLLDEHLRVKIADFGLCR
  | |   |. .|| |  ...||||||| |||| ..   ||..|||. |
AILLEMCQDVCEGMAYLERHCFIHRDLAARNCLVGDQCVVKVSDFGMTR
Kinase T14E8.1.AA Tec 899-995 36 5e-20 66.72 In-house 161-254 (254) Show / Hide 
Range on Protein: 899-995
Range on HMM: 161-254/254
Sequence Identity: 36% (36 aa)

PVRWFPPEISE-QGFGITSDIWSFGVVIWELFTRGSTPYSNMASWILILPWLKESETNRLRKPPYCPEKLYTDVMLACWKANPAERPQFSDLVTIIPN
||.| |||.     .   ||.|.|||  || |. |  || ||     .    . |.  || .|  |....| ..|  ||.  | ||| |..|   | .
PVKWCPPEVFHYSRYSSKSDVWAFGVLMWEVFSCGKMPYENMSNSEVV---EHVSQGHRLYRPHLCSMHIY-QIMYHCWHEKPEERPTFQQLLRQITE
Kinase T14E8.1.AA RTKC 956-993 39 2.3e-14 43.69 In-house 225-261 (261) Show / Hide 
Range on Protein: 956-993
Range on HMM: 225-261/261
Sequence Identity: 39% (15 aa)

RLRKPPYCPEKLYTDVMLACWKANPAERPQFSDLVTII
|| .|. |....| |.|..||. .|..|| ||..|. .
RLPCPEDCHKEVY-DMMMDCWMHTPHDRPTFSEVVHWL