Gene unc-51 (Nematode worm)

unc-51

Species: Nematode worm
Alias: Y60A3A.1, CE24516, unc-51, aSWK245, Y60A3.y, Y60A3.yx=(lfskn..fltr)
External Links: Wormbase Link ,
Annotation: WormBase Genetic Map location: V:24.3987, WormBase Physical Map location: V: 19996588-19988091,

Classification

Group: Other
Family: ULK
Subfamily: ULK

Sequence

Name Sequence Type Origin Length Description Download
unc-51.kin_dom Protein Kinase Domain Sugen global kinase HMM prediction 267 Kinase domain by global Sugen HMM Fasta, JSON
unc-51.AA Protein Genbank 856 None Fasta, JSON

Protein domain

Protein domains of unc-51.AA. The domains are annotated by HMM profiles from Pfam and SMART, as well as in-house data which includes HMMs of each individual kinase group, family and subfamily. Here is domain list in details, including sequence identity, significance and alignment. In particular, you can find can find the best hit kinase group/family/subfamily, which is helpful to understand the relationship between kinases.Kinase domain and best hit kinase group/family/subfamily are highlighted in red and blue. Visualized by pviz.

Usage: Zoom in selected region by dragging mouse and zoom out by double-clicking.

Show/hide domain list
Domain Protein name Domain Name Range Identity (%) Significance Score Profile Source Profile Range (length) Alignment
Kinase unc-51.AA ULK 9-275 33 2.5e-129 435.98 In-house 1-324 (324) Show / Hide 
Range on Protein: 9-275
Range on HMM: 1-324/324
Sequence Identity: 33% (111 aa)

YSKRDLLGHGAFA-IVYRGR-YVDRT-DVPVAIKAIAKKNISKSKN---------LLTKEIKILKELSSLKHEN--LVGLLKCTETPTH--VYLVMEFCN
|.... ||.|.|.  ||.||   . | .. ||.| | ||...|.||         || .||.|.|.| .|||.|   | |....||..|  .|..||.||
YCLNHCLGKGSFGVKVYKGRNKKTNTQNQYVACKMIDKKKMNKKKNEQEGQYMWQLLKNEIQIMKKLKELKHPNHHIVKLYDWFETSNHNNIYIIMEYCN

GGDLADYLQQKTTLNEDT----------IQHFVVQIAHALEAINKKGIVHRDLKPQNILLCNNSRTQ----NPHFTDIVIKLADFGFARFLNDGVMAATL
|||| .|.... .|.| |          ...|  ||. .. ...|..|.|||.||||||. |.   .    . |.  .|.|.||||||...... |....
GGDLEQYIKKNKKLPE-TEEKKRLSEQEAIQFFKQICNGFKELHKHNIIHRDIKPQNILIHNGQPKTDSKKV-HP-NGVLKIADFGFAKHVDNNNMEQQM

C----------GSPMYMAPEVIM----SMQYD-AKADLWSIGTILFQCLTGKAPFVAQTPPQLK-------------AYYEKTRELRPNIPE---WCSPN
|          |.|.||||....     ..|. .|.|.||.|.|....|.|| ||... . ...              .|.|.. .....|.    .||.
CQTCVNEKRIKGTPLYMAPQILQGQGEQKPYYDYKCDIWSLGCIFYEMLYGKYPFFSW-FNDQYLYIQKLINNGKEQQIYIKNQPIQFPKPPKDPKISPE

LRDLLLRLLKRNAKDRISFEDFFNHPFL
..||. |.|... |||||.|..||||..
CKDLIRRMLQYDEKDRISWEEIFNHPWF
Kinase unc-51.AA ULK 9-275 32 7.69999999999e-123 414.4 In-house 1-329 (329) Show / Hide 
Range on Protein: 9-275
Range on HMM: 1-329/329
Sequence Identity: 32% (109 aa)

YSKRDLLGHGAFAIVYRGRYVDRT---DVPVAIKAIAKKNISKSKNL---------LTKEIKILKELSSL-----KHENLVGLLKCTETPTH--VYLVME
|.... ||.|.|. ||.|| ...    .. ||.| | |. .....|.         |..||||.|.| |      .|.| | |....||..|  .|..||
YCLNHCLGKGSFGKVYKGRNKKTKDYVNEKVACKMIDKQKMNQKNNEQEGQYMWQLLKNEIKIMKKLKSPNRHKNHHPNIVKLYDWFETSNHNNIYIIME

FCNGGDLADYLQQKTTLNEDT----------IQHFVVQIAHALEAINKKGIVHRDLKPQNILLCNNSRTQ----NPHFTDIVIKLADFGFARFLNDG---
.|||||| .|.... .|.|||          ...|  ||. .. ...|..|.|||.||||||. |.   .    . |.  .|.|.||||||......   
YCNGGDLEQYIKKNKKLPEDTEEKKRLSEQEAIQFFKQILNGFKELHKHNIIHRDIKPQNILIHNGQPKTDSKKV-HP-NGVLKIADFGFAKHVDNDNME

---VMAAT----LCGSPMYMAPEVIM----SMQYD-AKADLWSIGTILFQCLTGKAPFVAQTPPQLK-AYYEKTRELRPNIP-------EW---------
    |...    |||.|.||||....     ..|. .|.|.||.|.|....|.|| ||.|. . ...  ...| ....|..|                  
QQMMMTCVNEKRLCGTPLYMAPQILQGQGEQKPYYDYKCDIWSLGCIFYEMLYGKPPFYAW-FNDQYLQIIQKLINNPPPWPQQIKKQPLQFPKDGNDPQ

CSPNLRDLLLRLLKRNAKDRISFEDFFNHPFL
.||...||. |.|... |||||.|..||||..
ISPECKDLIRRMLQYDEKDRISWEELFNHPWF
Kinase unc-51.AA S_TKc 9-275 32 3.7e-98 333.33 SMART 1-231 (231) Show / Hide 
Range on Protein: 9-275
Range on HMM: 1-231/231
Sequence Identity: 32% (92 aa)

YSKRDLLGHGAFAIVYRGRYVDRTDVPVAIKAIAKKNISKSKNLLTKEIKILKELSSLKHENLVGLLKCTETPTHVYLVMEFCNG--GDLADYLQQKTT-
| . ...|.|||. ||..| .. |.  |||| |         . . .||.|||.    .|.|.| |. . .. .|.|.|||.|.|  ||| ||.... . 
YEILRKIGKGAFGKVYKCRHKK-TGRIVAIKIIK--------EHIRREIQILKK----HHPNIVKLYDVFQD-DHLYMVMEYCDGDLGDLFDYIKKRGRH

-----LNEDTIQHFVVQIAHALEAINKKGIVHRDLKPQNILLCNNSRTQNPHFTDIVIKLADFGFARFLNDGVMAATLCGSPMYMAPEVIMSMQYDA-KA
     ..| ...... ||. ||| . ..||.||||||.||||..            .||..|||.||.|       |.||.| ||||||.   .|.  |.
GLRFPFPE-HARFYMYQICCALEYCHSHGIIHRDLKPENILLDE------------HIKICDFGLARQL------TTFCGTPWYMAPEVL---GYGKCKC

DLWSIGTILFQCLTGKAPFVAQTPPQLKAYYEKTRELRPNIPEWCSPNLRDLLLRLLKRNAKDRISFEDFFN-------HPFL
| ||.| ||. .|.|. ||      |... ..| .          || ..|.. ..|... ..|..  . ..       ||..
DWWSCGCILYEMLCGYPPFP-----QMQMMFKKIG----------SPEAKDFIRKCLQKDPEKRPTA-EALQDEWDIKCHPWF
Kinase unc-51.AA AGC 9-275 20 9.8e-89 228.82 In-house 1-395 (395) Show / Hide 
Range on Protein: 9-275
Range on HMM: 1-395/395
Sequence Identity: 20% (85 aa)

YSKRDLLGHGAFAIVYRGRYVD-----RTDVPVAIKAIAKKN---------ISKSKNL--------LTKEIKILKELSSLK-------HENLVG-LLKCT
.    ..| |.|  ||  | .|      |.   |.| . ||          . . ..         . .| .||..... .       | ..|  |  . 
FEFLKVIGKGSFGKVYLVRKKDGCHKKDTGKYYAMKVLKKKHKIVIKKKNMVEHTMTEHWKQDQGYVWEERNILEKCNHTHNHPIKSHHPFIVKILHYSF

ETPTH--VYLVMEFCN---------GG-DLADYLQ---QKTTLNEDTIQHFVVQ-------IAHALEAINK-KGIVHRD-LKPQNILLCNNSRTQNPHFT
....|  .|.|||...         || .|  .||   .. ...|......  .       |. ||| . . .||.||| ||| |||| ..         
QDKDHTYLYFVMEYMPRYVNDLYCGGGCELFLHLQGRRKEGRFDEERARFYAAEMQKICGCIVLALEYLHSHMGIIHRDYLKPENILLDED---------

DIVIKLADFGFARFLN---------------------------------------------------DGVMAATLCG--SPMYMAPEVIMSMQYDAKADL
   |||.|||..  ..                                                   ..... |.||  .| |||||..    |.  .| 
-GHIKLTDFGLCKEGMNDGEKGQQSQSNMKFHWHNKKYQKSNMDTNKCNPNNWQRNNMSQEDDTTRKKRDRTWTFCGPCTPEYMAPEIL----YGKACDW

WS--IGTILFQCLTGKAPFVAQTPP-------QLKAYYEKTR------ELRPNIP----------EWCSPNLRDLLLRLLKRNAKDRIS----------F
||   | .... |||. || ...|        . .  ..| .      . .. .|          .| ||...||. .||... ..|.           .
WSFGLGCLMYEMLTGYPPFYGDNPQENRHPFRNPMEMFQKIMNGRYFINWKVKFPFPEDPQFPEDRWFSPEAKDLIKKLLCKDPEKRLGCGGNDFGDKGA

EDFFNHPFL
|.  |||. 
EEIKNHPWF
Kinase unc-51.AA CAMK 14-275 22 4.8e-82 264.02 In-house 1-425 (425) Show / Hide 
Range on Protein: 14-275
Range on HMM: 1-425/425
Sequence Identity: 22% (95 aa)

LLGHGAFAIVYRGRYVDRTD-----------VPVAIKAIAKKNISK---------------------------SKNLLTKEIKILKELSS----LKHENL
 ||.|.|..|....    |            . |||| | || ...                           ..  . .||.|.| |..    |.|.|.
TLGRGSFGKVKLCIHKNTTGKERVHHIYTNGQKVAIKIIDKKKLKDKQNQDYSNCYKIDKSKCKHRYCWRRPKDRKNVRREIEIMKKLQGIGNKLDHPNI

VGLLKCTE------------TPTH--------VYLVM---EFCNGG----DLADYLQQK---------------TTLNEDTIQHFVVQIAHALEAINKKG
. |.   |            | ..        .|.||   |.| ||    || ||....                 ..|.  .... ||. |.. . ...
IKLYEVYEDPHYFKNTNDYET-SKQVFTKDKHMYMVMEIMEYCSGGELFDDLFDYIVEHGCYGEEFDQFDIVERGRFTEREARRYFRQICSAVHYCHSHN

IVHRDLKPQNILLCNNSRTQNPHFTD---------IVIKLADFGFARFLND------------------------GVMAATLCGSPMYMA-PEVIMSMQ-
|||||||| ||||..|.. ..|               ||..|||||.....                        | .  | ||.| ||| |||. . . 
IVHRDLKPENILLDDNNDDSDP-V-EHDEIFDWNNNNIKIIDFGFANKFDPGENNFMCSDYKGGEMHNQWTTPTEGQKMKTFCGTPEYMAAPEVLNGKGH

-------------YDAKADLWSIGTILFQCLTGKAPFVAQTPPQL----------KAYYEKTRELRPN-IPEW-----------------------CSPN
             |. |.| ||.| ||. .|.|. || . .  .           .  .|| .. . . .|..                       .|. 
CNMQNATDEEKPYYGPKCDMWSCGVILYIMLCGYPPFYGDCDNEICEDEWIGMNDYELFEKIMKGKYDFPPPYFSPISCNYGPEWWDDISDEFHHFVSQE

LRDLLLRLLKRNAKDRISFEDFFNHPFL
 .||. ..|... ..|.. |.  |||..
CKDLIRKMLQVDPEKRMTIEQCLNHPWM
Kinase unc-51.AA Pkinase 9-275 30 9e-80 276.13 Pfam 1-293 (293) Show / Hide 
Range on Protein: 9-275
Range on HMM: 1-293/293
Sequence Identity: 30% (92 aa)

YSKRDLLGHGAFAIVYRGRYVDRTDVPVAIKAIAKKNISKSKN-LLTK--EIKILKELSSLKHENLVGLLKCTETPTHVYLVMEFCNGG----DLADYLQ
| .   .| |.|. ||... ..  .  ||.| | |......|.  ...  ||.|.|.|.   |.| | |. . |...|.|.|||.|.||    ||.||..
YHIGRKIGSGSFGCVYKCHHKGTGK-IVAVKIIKKRHEKSWKDQTHRRLSEIQIMKRLN---HPNIVRLYDWFEDKDHIYMVMEYCEGGLYVMDLFDYIS

--QKTTL--NEDTIQHFVVQIAHALEAINKKGIVHRDLKPQNILLCNNSRTQNPHFTDIVIKLADFGFARF--LNDGVMAATLCGSPMYMAPEVIM-SMQ
  .....   |....... ||. .|| . ..||.||||||.|||. ||  .         .|..|||.|..  .  .. . |.||.| |||||||. .  
TWRHGCFYFSEWECKFYMYQILRGLEYCHSMGIIHRDLKPENILIDNNGHIDA------CVKICDFGLAKQFDY-NNS-MTTFCGTPWYMAPEVIRGGQY

YDAKADLWSIGTILFQCLTGKAPFVAQ----TPPQLKAYYEKTRE--LRPNIPEWCS-------------------PNLRDLLLRLLKRNAKDRISFEDF
|. |.| ||.| ||.. |.|. ||  .    .    .. ......  |. ..|.|||                   ....|.. ..|... |.|...|. 
YGPKVDMWSCGCILYEMLCGRPPFPGHCWHDN-HDQMQMICRIMGPPLHFDWPWWCSISYFFFRHWHFHWTFHNWSEECKDFIKWCLCKDPKKRPTAEQI

FNHPFL
..||..
LQHPWF
Kinase unc-51.AA Ciliate-E2 9-275 23 2.1e-78 266.8 In-house 1-365 (365) Show / Hide 
Range on Protein: 9-275
Range on HMM: 1-365/365
Sequence Identity: 23% (91 aa)

YSKRDLLGHGAFAIVYRG-RYVDRTDVP----------------VAIKAIAKKNISKS-KNLLTKEIKILKELS-------------SLKHENLVGLLKC
| .  ..| |.|..||.. .. .. ..                 |.|| .|.|...|. .. . .||.|..|.              .|.| |.. .  |
YKFIKKIGQGNFGSVYKCKVWKVQKQFAIKIIDQKQQRQQMQEKVKIKIYAMKIMKKNQIEQIKQEIHIMREINCFYKKINEKNILEQLNHPNIIKMYEC

TE--TPTHVYLVMEFCNGGDLADYLQQKTT-----------LNEDTIQHFVVQIAH---------------ALEAINKKG-IVHRDLKPQNILLCNNSRT
 .  . ...|||||.|.|||| ||.... .           ..|  |...  ||.                ||| . .|. |.|||.||.|||.      
FQEKDDNNIYLVMEYCQGGDLFDYIKNNKKKRNHEIEKDKYFTEKEIKYIMKQILQGFKTKAEFYIACIILALEYLHSKNNIIHRDIKPENILF------

QNPHFTDIVIKLADFGFARFLNDG--------------------------------VMAATLCGSPMYMAPEVIMSMQ---------YDAKADLWSIGTI
         ||..|||......|                                  |. |.||.|.|||||.... .         || |.|.||.| |
---------IKIIDFGLSKKYDDDNQNRTHKQQCKWYMFKNDTSRTPGYMDQIIQQNMFNTICGTPGYMAPEILNGKKYDNQQKQKGYDYKCDIWSLGVI

LFQCLTGKAPFVAQTPPQLKAYYEKTRELRPNIP----------------EW--CSPNLRDLLLR----LLKRNAKDRIS-FEDFFNHPFL
|...|.|| ||           ...  .   ..|                .|  .|..  ||. .    .|... . ||. .|. .|||..
LYEMLFGKPPF-----------QQQIKQCKIDFPCPEWQKDTQCIQCKWKSWKKWSQECKDLIKKFGKRMLQKDPEKRITGWEQILNHPWF
Kinase unc-51.AA CAMKL 9-275 31 9.4e-77 244.44 In-house 1-297 (297) Show / Hide 
Range on Protein: 9-275
Range on HMM: 1-297/297
Sequence Identity: 31% (98 aa)

YSKRDLLGHGAFAIVYRGRYVDRTDVPVAIKAIAKKNIS-KSKNL-------------LTKEIKILKELSSLK-HENLVGLLKCTETPTH------VYLV
|   . ||.|.|. |  .. .  | . |||| | || |. . ...             ...||.|.| |.    |.| . |. . |||.|      .|||
YRIGKTLGKGSFGKVKLATHIRTTGEKVAIKIIDKKKIWNDPWMKKNKCGQKHESDMRIRREIQIMKMLN-IGKHPNIIKLYEVIETPEHDIETKKIYLV

MEFCNGGD--LADYLQQK----TTLNEDTIQHFVVQIAHALEAINKKGIVHRDLKPQNILLC-NNSRTQNPHFTDIVIKLADFGFARFLND-----GVMA
|| | ||.  | ||....      . |.  ...  || .|.. . ..||||||.|| ||||  |...         .||..||||. .  .     | . 
MEYCSGGEMDLFDYIVKHGHRRGRMPEHEARRYFRQIVSAVNYCHSHGIVHRDIKPENILLDENGNN---------NIKIIDFGFSNMYRPCIFGPGQKL

ATLCGSPMYMAPEVIMS--MQYD-AKADLWSIGTILFQCLTGKAPFVAQTPP-----QLKAYYEKTRELRPNIPEWCSP-NLRDLLLRLLKRNAKDRISF
 | |||| |||||.. .   .||  |.| ||.| ||.  ..|. || ..| .         .|.|....  ..| |...  .|||. ..|..| ..|.. 
KTFCGSPPYMAPEIFQGNNKPYDGPKVDIWSCGVILYAMVCGYLPFDDDTYNKQGKDNI-YLYWKIMCG-YYPPIWYHVSDCRDLIRKMLQVNPEKRPTI

EDFFNHPFL
..  |||..
HQIMNHPWM
Kinase unc-51.AA STE 9-275 21 5.3e-72 245.52 In-house 1-359 (359) Show / Hide 
Range on Protein: 9-275
Range on HMM: 1-359/359
Sequence Identity: 21% (81 aa)

YSKRDLLGHGAFAIVYRGRYVD-----RTDVP---------VAIKAIAKKNIS----------------KSKNLLTKEIKILKELSSLKHENLVGLLKCT
. . . .|.|||  ||......     .|.           .||| . ..| .                . .. . |||||.|....  |.| |  . | 
WEGIEKIGKGAFGTVYKAMNHKNCNIHKTGEVENNGETGEIMAIKQMNLENCNNKDENQENQELENKNHEEMQQILKEIKIMKKCNHM-HPNIVKYYGCY

ETP-------THVYLVMEFCNGGDLADYLQQK--------------TTLNEDTIQHFVVQIAHA-LEAINKKGIVHRDLKPQNILLCNNSRTQNPHFTDI
.         ......||...|| | | ...|              ....|. | ....|| .. |. . ...|.|||.||.||||              
FKEGHNHKNDDELWICMEYMDGGSLDDIIKHKYGCGKPLNHNRQHQHRFPESQIAYICRQILKGLLYYLHSHHIIHRDIKPANILL--------------

VIKLADFGFARFLND-----------------GVMAATLCGSPMYMAPEVIMSMQ------YDAKADLWSIGTILFQCLTGKAPFVAQTPPQLKAYYEKT
 .||.|||..  |.|                 . .  |..|.| .||||||. ..      ||.|.| ||.|  .   .||| |.   .|..   .  . 
-VKLCDFGVCGQLTDSMANIQSNNIIDCIETMQQKRNTFVGTP-WMAPEVIQQNGQGRDKGYDTKCDIWSLGCTIIEMATGKPPWHDMHPMRAMFMIPFN

R-------------ELRPNIPE-------------------WCSPNLRDLLLRLLKRNAKDRISFEDFFN--HPFL
              .  | .|.                    .||...| . . |... ..| . ..  .  |||.
YHMQQQFEQLCIVNGPPPPLPDHLSQNEMISYGGSGTTYPHKWSPEFKDFINKCLQKDPNKRPTASQLLKSEHPFI
Kinase unc-51.AA Ciliate-E2-Unclassified 9-275 25 7.4e-72 245.04 In-house 1-352 (352) Show / Hide 
Range on Protein: 9-275
Range on HMM: 1-352/352
Sequence Identity: 25% (92 aa)

YSKRDLLGHGAFAIVYRGRYVDRTDVPVAIKAIAKKNISKSKNLLT--------KEIKILK-------------ELSSLKHENLVGLLKCTETPTHVYLV
| .   .|.|.|..||. .  .      |.| . |..| |.|. ..        ||....|             .|....|...| .. | ..  ..|.|
YKIIKQIGQGGFGKVYKCQHKKQK-QYYAMKYMKKIQIYKQKQIMNKDEIMNEMKEMNNKKKYHQRKYNKIMQQILLNHPHPFIVKMFYCFQDKQNIYIV

MEFCNGGDLADYLQQKTT-----------------LNEDTIQ-----HFVVQIAHALEAINKKG-IVHRDLKPQNILLCNNSRTQNPHFTDIVIKLADFG
||.|.|||| .|.... .                 . |  ..     ..  ||  .|| . .|. |.|||.||.|||. || .          ||..|||
MEYCEGGDLWQYIKKRKKQKQKGNDLFHNMKQRKIFTEQQAKYKKAKFYFAQILQGLEYLHHKNNIIHRDIKPENILFDNNGK-------NYYIKIIDFG

FARFLNDG----------------VMAATLCGSPMYM----APEVIMSMQYD----AKADLWSIGTILFQCLTGKAPFVAQTPPQ-------------LK
.......                  |. | ||.|.||    ||||... .||     |.| || | ||...|.|. || ...  |              |
ISKKYQQNNNCDTNQQQKMQIWKQQMMWTFCGTPNYMPQYTAPEVLQGQNYDHSKAYKCDIWSLGVILYEMLFGYYPFYDNNCEQHQQLITQWINNAYRK

AYYEKT--RELRPNIPEW------CSPNLRDLLL----RLLKRNAKDRISFEDFFNHPFL
 .|..   ...  .  .|       ||.  |..     ..|| | . ||.||. .|||..
QLYQNIKQKNIQFPKFPWQQIPKHWSPEAKDFINDLLQKMLKKNPNKRITFEQILNHPWF
Kinase unc-51.AA CAMK1 9-218 35 3.5e-63 182.48 In-house 1-216 (276) Show / Hide 
Range on Protein: 9-218
Range on HMM: 1-216/276
Sequence Identity: 35% (80 aa)

YSKRDLLGHGAFAIVYRGRYVDRT--DVPVAIKAIA-KKNISKSK----NLLTKEIKILKELSSLKHENLVGLLKCTETPTHVYLVMEFCNGGDLADYLQ
|  .. .| |||..||..   .    . ..|||.|  ||...|..    ..| .|| |.| .| ..|.| . .    |...|.||||| ..||.| |   
YEFGKEIGRGAFSEVYLCTHKETQTNGKQYAIKCIDKKKFMKKKDMQKQEALENEIEIMKKVSKIDHPNIIKFYEWYESDNHFYLVMELVTGGELFDRIV

QKTTLNEDTIQHFVVQIAHALEAINKKGIVHRDLKPQNILLCNNSRTQNPHFTDIVIK--LADFGFARFLNDGV-MAATLCGSPMYMAPEVIMS---MQY
.|.  .|.   | . ||. |.| . .||||||||||.|.|. ...        |  ||  .|||| ........ .  | ||.| |.||||.       |
EKGNYTEKDARHIMKQILSAVEYMHSKGIVHRDLKPENLLYYDKD-------EDSKIKRSIADFGLSKIFDHDENLMKTACGTPGYVAPEVLECKKDKPY

DAKADLWSIGTILFQCLTGKAPF
| . |.|||| |..  |.|  ||
DKACDMWSIGVITYILLCGYPPF
Kinase unc-51.AA TKL 15-263 20 2.7e-58 199.97 In-house 1-354 (364) Show / Hide 
Range on Protein: 15-263
Range on HMM: 1-354/364
Sequence Identity: 20% (74 aa)

LGHGAFAIVYRGRYVD-------RTDVPVAIKAIAKKNISKSKN-----------------------LLTKEIKILKELSSLKHENLVGLLKCTETPTH-
.| |.|..||.|..         .|. .||.| . ..| ...                         .  .|.. .. .|.|.|.|.| .. .   |.. 
IGSGGFGEVYKGKWRGWGGKCPSDTGKDVAVKKFKSHNDDEFTKNSQENNDNNNYSDMQLNDPEASWFRFFEEEEIMMMSRLRHPNIVQFMGYCCCPPCG

------------VYLVMEFCNGGDLADYLQQKTTLNEDTIQHFVVQIAHALEAINK--------KGIVHRDLKPQNILLCNNSRTQN----PHFTDIVIK
             ..|||.| ||.| .||.       . . ... .|| ...            ..|.|||||..|||. .| ....    ..  |...|
CVCMHPVGPWGQLCIVMEYCPGGSLLHYLH------WHQRCRWALDIARGMNYLHSMNPKWCTKPPIIHRDLKSKNILVDENWTNVSNYMYNPNADWCCK

LADFGFARFL--------------------NDGVMAATLCGSPMYMAPEVIMSM----------------QYDAKADLWSIGTILFQCLTGKAPFVAQTP
..|||..||.                    | . .  | ||.| .|||||.. .                .|. |.| .| | .|. .||.. |.  . .
ICDFGLSRFMSQSGNMNDTMTTMMESAEHQNNRKTTMTQCGTPRWMAPEVLRGQMNYTEKVGIDEFCKGFEYSEKCDVYSFGIVLWEILTRCRPYYDYPY

PQLK------AYYEKTR--ELRPNIP------------EWCSPNLRDLLLRLLKRNAKDR
.. .      .. ..     ||| ||            . | | ...|. .  . ....|
MPMIFQDPFEEMFMMVCDKGLRPPIPPIWQNHHKMCPCPDCPPSMKKLMQDCWDHDPEKR
Kinase unc-51.AA Pkinase_Tyr 9-268 29 6.2e-33 112.17 Pfam 1-265 (270) Show / Hide 
Range on Protein: 9-268
Range on HMM: 1-265/270
Sequence Identity: 29% (83 aa)

YSKRDLLGHGAFAIVYRGRYV---DRTDVPVAIKAIAKKNISKS---KNLLTKEIKILKEL-SSLKHENLVGLL-KCT-ETPT-HVYLVMEFCNGGDLAD
 ..   ||.|||  ||.|..    | |..|||.| . | . ...   .  . .|.||.|.| .   |.|.| |.  || .    ..|.|||.. .||| |
ITFGKKLGEGAFGEVYKGTWKGDPDNTKIPVAVKML-KEGAMHEQNCREDFMREAKIMKQLGH---HPNIVRLYGVCTDQGEPNQIYIVMEYMPHGDLLD

YLQQ----KTTLNEDTIQHFVVQIAHALEAINKKGIVHRDLKPQNILLCNNSRTQNPHFTDIVIKLADFGFARFL-NDGVM--AATLCGSPM-YMAPEVI
||..    |  |.  .. .. .||| ..|    |...||||   |.|. .          . |.| .||| || . ||.    ... .  |   ||||.|
YLRKHREDKQPLTMKDLLQMCWQIAKGMEYLESKNCIHRDLAARNCLVTE----------NNVVKICDFGLARDIYNDDYYYRKRGGGKLPIKWMAPECI

MSMQYDAKADLWSIGTILFQCLT-GKAP-FVAQTPPQLKAYY-EKTRELRPNIPEWCSPNLRDLLLRLLKRNAKDRISFED
. . .  | | || |  ..  .| |. | .   .. ....|  |.    |  .|| |.. . ||...  . ...|| .|..
NYGKFTTKSDVWSFGVLMWEIFTYGEQPTYPGMSNEEVYEYIYED--GYRMPCPENCPDEIYDLMKQCWHYDPEDRPTFSE
Kinase unc-51.AA TyrKc 9-275 22 4.5e-26 93.85 SMART 1-280 (280) Show / Hide 
Range on Protein: 9-275
Range on HMM: 1-280/280
Sequence Identity: 22% (69 aa)

YSKRDLLGHGAFAIVYRGRYVDRTDVPVAIKAIAKKNISKSKNLLTKEIKILKELSSL--KHENLVGLLKCTETP-------THVYLVMEFCNGGDLADY
 .. . ||.||| .||.|..     ..||.| . .      .  . .|..|...   |  .|.|.| |. .  ..         ...|||.. .||| ||
ITLGKKLGEGAFGEVYKGTWK----IQVAVKMLKEDA----REDFMREARIMCK---LGGHHPNIVRLYGVCTQQGRNFMYIEPLMIVMEYMPHGDLKDY

LQQKTT-LNEDTIQHFVVQIAHALEAINKKGIVHRDLKPQNILLCNNSRTQNPHFTDIVIKLADFGFARFLNDG--------VMAATLCGSPM------Y
|. .   |. ..  .| .|||   | . .|...||||   |.|. .|           ..| .||| .|.. |.        .  ..  ..         
LRKHRPKLCMKDLLSFCWQIACGMEYLHSKNCIHRDLAARNCLVGENH----------TVKISDFGLSRDIYDDDQQGESKDYYRKKEHKGGKTMLPIRW

MAPEVIMSMQYDAKADLWSIGTILFQCLT-GKAPFVA-----QTPPQLKAYYEKT-RELRPNI--PEW----CSPNLRDLLLRLLKRNAKDRISFEDFFN
||||.|.   .  | | || |  ..  .| |. |         .. .. .| ..  |  .|    |      |.. . .. ..  .....|| .|..   
MAPECINYGKFTTKSDVWSFGVCMWEIFTYGQQPYPGMIQQMMSNQEVIEYVKQGYRMPQPPNDYP-MSFVCCPDEMYQIMKQCWHEDPEDRPTFSEI--

HPFL
| ..
HECF
Kinase unc-51.AA CAMK1 250-275 30 8e-06 12.83 In-house 251-276 (276) Show / Hide 
Range on Protein: 250-275
Range on HMM: 251-276/276
Sequence Identity: 30% (8 aa)

DLLLRLLKRNAKDRISFEDFFNHPFL
|..  .|. . | |...|.. |||..
DFIKHMLEVDPKKRYTCEQCLNHPWI
DUF3543 unc-51.AA DUF3543 642-850 21 2.2e-76 264.84 Pfam 1-275 (275) Show / Hide 
Range on Protein: 642-850
Range on HMM: 1-275/275
Sequence Identity: 21% (60 aa)

EIVLGEEHKQILAKLRFVAELVDTLIHVAEQKDNPLASAM------ASRRQLL--------TTGTSTTNTSSPYRRAEQLVVYVRALHMLSSALLLAQTN
. .. .||.....||...| . | . ..||.| ..|...|      .......        .....|..... ....|.|| ||.||..|.... .|. .
QTSMDDEHTRTVQKLEECATRSDCVYGFAEVKYKQLIPLMPSVSTYGLGDANVQGRDDSMHQDDGLTPDAIVTWKSEEALVLYVKALSLLAKSMDIASAW

VAN--------------RVLHP-SVAVQQVLNQLNDKYHQCLVRSQELASLG------LPGQDPAMAV--------------------ISAERIMYRHAI
...              . |.| |....||..........||.... ... .      ||...| ..                     ..||..|| .|.
WYRKNRGEDFNMTRDSSNQLCPTSNRINQVVQWIRERFNECLEKCEFVRLKLQEAQKRLPEDHPSHPKNHSNESSSSGSSNDVVVSSGVTAEKLMYDRAL

ELCQAAALDELFG-NPQLCSQRYQTAYMMLHTLAEQV----------NCDQDKTVLTRYKVAVEKRLRILERQGF
|....||..|||| ... | ..|.||..||. |.|.           ..|.||... .|.|...||| .| ....
EMSRTAAINELFGEDLPGCEIAYHTAIWMLEALLENDEDEDKDENDGLDDEDKQMVEKYIVSIRKRLSVLRKKMY