Gene W09C5.5 (Nematode worm)

W09C5.5

Species: Nematode worm
Alias: CE20167, aSWK065, W09C5.5
External Links: Wormbase Link ,
Annotation: WormBase Genetic Map location: I:20.36, WormBase Physical Map location: I: 13656452-13648368

Classification

Group: CAMK
Family: PKD

Sequence

Name Sequence Type Origin Length Description Download
W09C5.5.kin_dom Protein Kinase Domain Sugen global kinase HMM prediction 260 Kinase domain by global Sugen HMM Fasta, JSON
W09C5.5.AA Protein Genbank 722 None Fasta, JSON

Protein domain

Protein domains of W09C5.5.AA. The domains are annotated by HMM profiles from Pfam and SMART, as well as in-house data which includes HMMs of each individual kinase group, family and subfamily. Here is domain list in details, including sequence identity, significance and alignment. In particular, you can find can find the best hit kinase group/family/subfamily, which is helpful to understand the relationship between kinases.Kinase domain and best hit kinase group/family/subfamily are highlighted in red and blue. Visualized by pviz.

Usage: Zoom in selected region by dragging mouse and zoom out by double-clicking.

Show/hide domain list
Domain Protein name Domain Name Range Identity (%) Significance Score Profile Source Profile Range (length) Alignment
PKD_Nterm_DUF W09C5.5.AA PKD_Nterm_DUF 12-92 39 2.9e-44 145.42 In-house 1-87 (87) Show / Hide 
Range on Protein: 12-92
Range on HMM: 1-87/87
Sequence Identity: 39% (34 aa)

DHVVLRYGGTREMVPLIRHEQMLDMLMERARQIVQG-FGNLDTRN-----MYLFRHEYNSPTLLYPITSASQITSGSILEIILVDRT
.|.....|..||||....||..|..|.|.|.|.... .......|     .|||||.||||..|..|||||..|.|...||.|....
CHFHFQCGFHREMVCVEGHELTLTALKELACQFIEQKYPDCGCCNRLYDKIYLFRHDYNSPNILQMITSASDVTEGCLIEIVLSACP
C1_1 W09C5.5.AA C1_1 99-151 38 5.2e-14 55.07 Pfam 1-55 (55) Show / Hide 
Range on Protein: 99-151
Range on HMM: 1-55/55
Sequence Identity: 38% (21 aa)

HVVEPE-SYMRPTFCDFCGEMLTG-LMRQGVKCKNCNGNFHKRCSNAARNNCGAP
|  ..  .. .||||. |||.. | | .||.|| .|. |.|.||.. . ..||  
HHWVHHWNFKQPTFCCHCGEFCWGWLGHQGWKCQWCHYNCHHRCHMKVPPECGCN
C1 W09C5.5.AA C1 99-148 24 3.2e-13 51.18 SMART 1-61 (61) Show / Hide 
Range on Protein: 99-148
Range on HMM: 1-61/61
Sequence Identity: 24% (15 aa)

HVVEPESYMRPTFCDFCGEMLTGLMRQ-----GVKCKNCNGNFHKRCSNAARN-------NC
|  .  .. .||.|. |..|. |. .|     |..| .|. ..||.|.  . .       .|
HHWHWWRF-KPTYCCHCRKMIWGMFKQHWKMQGYRCSWCKYKCHKKCHDKVPQQSHQDGWMC
C1_3 W09C5.5.AA C1_3 110-141 21 0.003987 9.45 Pfam 1-30 (30) Show / Hide 
Range on Protein: 110-141
Range on HMM: 1-30/30
Sequence Identity: 21% (7 aa)

TFCDFCGEMLTGLMRQGVKCKNCNGNFHKRCS
 .|. ||. . .  . . .|  |. ..|..| 
FTCNCCGLPIYR--DPFYHCMQCDFMLHEDCA
C1_1 W09C5.5.AA C1_1 187-239 32 4e-14 55.49 Pfam 1-55 (55) Show / Hide 
Range on Protein: 187-239
Range on HMM: 1-55/55
Sequence Identity: 32% (18 aa)

HTLIEH-SYRQFTVCKVCDHLLVG-LVKQGLKCRDCGVNVHRKCAMELASNCVLS
|  ..| ...| | |..|. .. | | .||.||..|..|.| .|.| ....| ..
HHWVHHWNFKQPTFCCHCGEFCWGWLGHQGWKCQWCHYNCHHRCHMKVPPECGCN
C1 W09C5.5.AA C1 187-236 22 4.3e-14 54.06 SMART 1-61 (61) Show / Hide 
Range on Protein: 187-236
Range on HMM: 1-61/61
Sequence Identity: 22% (14 aa)

HTLIEHSYRQFTVCKVCDHLLVGLVKQ-----GLKCRDCGVNVHRKCAMELAS-------NC
|. ..... . | | .|.... |. ||     |..|..|....| ||.  ...       .|
HHWHWWRF-KPTYCCHCRKMIWGMFKQHWKMQGYRCSWCKYKCHKKCHDKVPQQSHQDGWMC
C1_3 W09C5.5.AA C1_3 198-229 21 3e-06 17.43 Pfam 1-30 (30) Show / Hide 
Range on Protein: 198-229
Range on HMM: 1-30/30
Sequence Identity: 21% (7 aa)

TVCKVCDHLLVGLVKQGLKCRDCGVNVHRKCA
  |..|.. . .    . .|  |  ..|..||
FTCNCCGLPIYR--DPFYHCMQCDFMLHEDCA
PH W09C5.5.AA PH 279-407 13 4e-06 27.46 SMART 1-82 (82) Show / Hide 
Range on Protein: 279-407
Range on HMM: 1-82/82
Sequence Identity: 13% (17 aa)

KKLEGWMMHFILSDPERRLKHYWMMQSNAIHLYNEYSEGIGVNPNRVYRIIPLAEITSVVQNNGKSVLAKHPPHCFEIRTTTNTVFCVGEDYHAFSGGPP
  .|||...       |. |.. .. .. ...| .          .   .||| .. .|.              ||||.. ..                 
VIKEGWLYKKS---K-RWKKRWFVLFNDCLYYYKDK---------KPKGSIPLSDC-TVRE-P-----------CFEIHH-DR-----------------

KKIPRSMSVRPSSNTTMWFQFIKESLQPP
      .. . ..  ..|.| |.. ... 
---TYYFQCESEEEMQEWMQAIQKAIHNN
C1_1 W09C5.5.AA C1_1 352-365 20 5.974172 3.47 Pfam 1-15 (55) Show / Hide 
Range on Protein: 352-365
Range on HMM: 1-15/55
Sequence Identity: 20% (3 aa)

HCFEIR-TTTNTVFC
| .. . .  ...||
HHWVHHWNFKQPTFC
Kinase W09C5.5.AA PKD 426-685 69 3.9e-219 734.28 In-house 1-260 (260) Show / Hide 
Range on Protein: 426-685
Range on HMM: 1-260/260
Sequence Identity: 69% (181 aa)

VLSDKTLGSGQFGTVYSAIQRHSGKEVAVKVISKERFSKKGSGAESMRAEVAILQQTCHPGIVCLEFMCETKDKIFVVMEKMNGDMLEMILSQELGRLNS
...|..|||||||.||..|.||.|..||||||.|.||..|.||.|.||.|||||||.||||.||||.||||.|.||||||||.|||||||||.|.||||.
IFPDEVLGSGQFGIVYGGIHRHTGRHVAVKVIDKLRFPTKQSGEEQMRNEVAILQQVCHPGVVCLECMCETPDRIFVVMEKMHGDMLEMILSSEKGRLNE

RATKFLLVQILCALKYLHDQGIAHCDLKPENVLLSDMGSNFPQTKICDFGYARFIPESQFRKTVVGTPAYLPPEVLQRKGYNKSLDMWSVGVIIYVTLSG
|.||||..||||||||||.|.|.||||||||||||.|||.|||.|.||||.||.|.|..||..||||||||.||||..||||.|||||||||||||.|||
RVTKFLITQILCALKYLHHQNIVHCDLKPENVLLSSMGSDFPQVKLCDFGFARIIGEKSFRRSVVGTPAYLAPEVLRNKGYNRSLDMWSVGVIIYVSLSG

TFPFNEGEEISEQIQNASFMFPTEPWSEVEPLAVDLIQKLLKVEIEARMSIEQCLDHGWL
||||||.|.|..|||||.||.|..||.|....|.|||..||.|....|.....||.|.||
TFPFNEDEDINDQIQNAAFMYPPNPWKEISENAIDLINNLLQVKMRKRYTVDKCLSHPWL
Kinase W09C5.5.AA CAMK 431-685 23 1.8e-103 334.3 In-house 1-425 (425) Show / Hide 
Range on Protein: 431-685
Range on HMM: 1-425/425
Sequence Identity: 23% (100 aa)

TLGSGQFGTVYSAIQRHSG------------KEVAVKVISKERFSK------------------------KGSGAESMRAEVAILQQ-------TCHPGI
|||.|.||.|. .|.....            ..||.|.|.|.. ..                        ...  ...| |..|...         || |
TLGRGSFGKVKLCIHKNTTGKERVHHIYTNGQKVAIKIIDKKKLKDKQNQDYSNCYKIDKSKCKHRYCWRRPKDRKNVRREIEIMKKLQGIGNKLDHPNI

VCLEFMCE------------TKDK--------IFVVM---EKMNG-----DMLEMILSQEL-------------GRLNSRATKFLLVQILCALKYLHDQG
. |  . |            | .|        .. ||   | . |     |....| ...              ||.. | ....  ||..|..|.|...
IKLYEVYEDPHYFKNTNDYET-SKQVFTKDKHMYMVMEIMEYCSGGELFDDLFDYIVEHGCYGEEFDQFDIVERGRFTEREARRYFRQICSAVHYCHSHN

IAHCDLKPENVLLSDMGSNFP-------------QTKICDFGYARFIPE------------------------SQFRKTVVGTPAYLP-PEVLQR-----
|.|.||||||.||.| .....             . ||.||| |.....                         |  ||..|||.| . ||||..     
IVHRDLKPENILLDDNNDDSDPVEHDEIFDWNNNNIKIIDFGFANKFDPGENNFMCSDYKGGEMHNQWTTPTEGQKMKTFCGTPEYMAAPEVLNGKGHCN

---------KGYNKSLDMWSVGVIIYVTLSGTFPFNEG---------------EEISEQIQNASFMFPTEP------------WSEVEPL--------AV
         ..|... ||||.||| |. |.|..||..                .|. |.|... . || ..            |...           . 
MQNATDEEKPYYGPKCDMWSCGVILYIMLCGYPPFYGDCDNEICEDEWIGMNDYELFEKIMKGKYDFPPPYFSPISCNYGPEWWDDISDEFHHFVSQECK

DLIQKLLKVEIEARMSIEQCLDHGWL
|||.|.|.|. | ||.|||||.| |.
DLIRKMLQVDPEKRMTIEQCLNHPWM
Kinase W09C5.5.AA RAD53 427-685 32 5.3e-90 268.23 In-house 2-305 (305) Show / Hide 
Range on Protein: 427-685
Range on HMM: 2-305/305
Sequence Identity: 32% (98 aa)

LSDKTLGSGQFGTVYSAIQRHSGKEVAVKVISKER-F---SKKGSGAESMRAEVAILQQTCHPGIVCLEFMCETK-DKIFVVMEKMNG-DMLEMILSQEL
. .|.|||| ||||. |. .  .. ||.| |.| . |   ..  . ..... || ||.   || |. ..  ..|. .  . |.|.|.| . .. | |...
YMSKELGSGNFGTVKLAYEKKTCQKVAIKIIDKKKFFIRCMHTIKKMDQVMNEVEILKKLNHPCIIRIYDIFDTPQKYYYMVLELMTGGELFNKIVSNKR

GR---LNSRATKFLLVQILCALKYLHDQGIAHCDLKPENVLLSDMGSNF--------------PQTKICDFGYARFIPESQFRKTVVGTPAYLPPEVLQR
 .   ..  . |... |.. |.|||||.||.| ||||||.|... . .                . || ||| ..|. |..| ||  |||.|. |||.  
-CQMGFDEDTCKYYFYQMCDAVKYLHDNGICHRDLKPENILCNHQDEECPQVQLGPWDEDEISFLIKITDFGLSKFVGEGSFMKTMCGTPQYVAPEVITS

K---------------GYNKSLDMWSVGVIIYVTLSGTFPFNEG-------EEISEQIQN-ASFMFPTEPWSEVEPLAVDLIQKLLKVEIEARMSIEQCL
|               ||.|. |.|| |.| |..|.|. || ..         . ||| | ... ||.. |...   | |||...|.|. |.| .|.. |
KGHNCYHENEERQVQVGYTKKVDCWSMGCILYICLCGYPPFSDDYTQEMHCMQLFEQIKNQGKYHFPHPYWDRISEEAKDLIKWMLCVDPEKRYTIDEAL

DHGWL
 | |.
NHPWM
Kinase W09C5.5.AA S_TKc 426-685 32 6.4e-89 302.64 SMART 1-231 (231) Show / Hide 
Range on Protein: 426-685
Range on HMM: 1-231/231
Sequence Identity: 32% (88 aa)

VLSDKTLGSGQFGTVYSAIQRHSGKEVAVKVISKERFSKKGSGAESMRAEVAILQQTCHPGIVCLEFMCETKDKIFVVMEKMNG---DMLEMILSQELGR
    ...|.| ||.|| .. ...|..||.|.|.           |..| |..||..  || || |  .... |....||| ..|   |....| ..  ..
YEILRKIGKGAFGKVYKCRHKKTGRIVAIKIIK-----------EHIRREIQILKK-HHPNIVKLYDVFQD-DHLYMVMEYCDGDLGDLFDYIKKRGRHG

----LNSRATKFLLVQILCALKYLHDQGIAHCDLKPENVLLSDMGSNFPQTKICDFGYARFIPESQFRKTVVGTPAYLPPEVLQRKGYNK-SLDMWSVGV
    ..   ..|.. ||.|||.|.|..|| |.||||||.||..      . |||||| ||..      .|..||| |..||||   ||.| . |.||.|.
LRFPFPE-HARFYMYQICCALEYCHSHGIIHRDLKPENILLDE------HIKICDFGLARQL------TTFCGTPWYMAPEVL---GYGKCKCDWWSCGC

IIYVTLSGTFPFNEGEEISEQIQNASFMFPTEPWSEVEPLAVDLIQKLLKVEIEARMSIEQCLD-------HGWL
|.|  |.|  ||    .. . ...              | | |.|.|.|... | |... ..|        | |.
ILYEMLCGYPPFP---QMQMMFKKIG-----------SPEAKDFIRKCLQKDPEKRPTA-EALQDEWDIKCHPWF
Kinase W09C5.5.AA Pkinase 426-685 30 1.8e-75 261.85 Pfam 1-293 (293) Show / Hide 
Range on Protein: 426-685
Range on HMM: 1-293/293
Sequence Identity: 30% (91 aa)

VLSDKTLGSGQFGTVYSAIQRHSGKEVAVKVISKERFSKKGSGAESMRAEVAILQQTCHPGIVCLEFMCETKDKIFVVMEKMNGD----MLEMILS-QEL
    ...||| ||.|| .. . .||.||||.|.|.. ...   .   ..|..|..  .|| || |  ..|.||.| .||| ..|.     |  ..| .. 
YHIGRKIGSGSFGCVYKCHHKGTGKIVAVKIIKKRHEKSWKDQTHRRLSEIQIMKRLNHPNIVRLYDWFEDKDHIYMVMEYCEGGLYVMDLFDYISTWRH

GRL--NSRATKFLLVQILCALKYLHDQGIAHCDLKPENVLLSDMGSNFPQTKICDFGYARF--IPESQFRKTVVGTPAYLPPEVLQ-RKGYNKSLDMWSV
|..    .  || . |||..|.|.|..|| |.||||||.|... | . .  |||||| |..  .  ..  .|..||| |..|||.. ...| .. ||||.
GCFYFSEWECKFYMYQILRGLEYCHSMGIIHRDLKPENILIDNNGHIDACVKICDFGLAKQFDY-NNS-MTTFCGTPWYMAPEVIRGGQYYGPKVDMWSC

GVIIYVTLSGTFPFNEG--------EEISEQIQNASFMFPTEPWSEVE-----------------PLAVDLIQKLLKVEIEARMSIEQCLDHGWL
|.|.|  |.| .|| .          .. ..|  . ..|. . |...                  . . |.| ..|..  . | ..||.| | |.
GCILYEMLCGRPPFPGHCWHDNHDQMQMICRIMGPPLHFDWPWWCSISYFFFRHWHFHWTFHNWSEECKDFIKWCLCKDPKKRPTAEQILQHPWF
Kinase W09C5.5.AA CAMKL 426-685 30 1.5e-72 230.84 In-house 1-297 (297) Show / Hide 
Range on Protein: 426-685
Range on HMM: 1-297/297
Sequence Identity: 30% (91 aa)

VLSDKTLGSGQFGTVYSAIQ-RHSGKEVAVKVISKERFSKKGSGAESMRA-----------EVAILQQTC---HPGIVCLEFMCETKDK------IFVVM
    |||| | ||.|  |.  |. |..||.|.| |.. ...       .            |..|...     || |. |  . ||...      |. ||
YRIGKTLGKGSFGKVKLATHIRTTGEKVAIKIIDKKKIWNDPWMKKNKCGQKHESDMRIRREIQIMKMLNIGKHPNIIKLYEVIETPEHDIETKKIYLVM

EKM-NGD--MLEMILSQEL--GRLNSRATKFLLVQILCALKYLHDQGIAHCDLKPENVLLSDMGSNFPQTKICDFGYARF-----IPESQFRKTVVGTPA
|   .|.  ....| ...   ||.  . ....  ||..|..|.|..||.| |.||||.||.. |.|  . ||.||| . .     ... |. ||  |.|.
EYCSGGEMDLFDYIVKHGHRRGRMPEHEARRYFRQIVSAVNYCHSHGIVHRDIKPENILLDENGNN--NIKIIDFGFSNMYRPCIFGPGQKLKTFCGSPP

YLPPEVLQR--KGYN-KSLDMWSVGVIIYVTLSGTFPFNEGE---------EISEQIQNASFMFPTEPWSEVEPLAVDLIQKLLKVEIEARMSIEQCLDH
| .||..|.  | |. .  |.|| ||| |. . |..||..           .  ..|    ...|  .|..|   . |||.|.|.|  | |..|.| . |
YMAPEIFQGNNKPYDGPKVDIWSCGVILYAMVCGYLPFDDDTYNKQGKDNIYLYWKIMCG-YYPP--IWYHVS-DCRDLIRKMLQVNPEKRPTIHQIMNH

GWL
 |.
PWM
Kinase W09C5.5.AA Ciliate-E2 426-685 22 5.8e-67 228.79 In-house 1-365 (365) Show / Hide 
Range on Protein: 426-685
Range on HMM: 1-365/365
Sequence Identity: 22% (84 aa)

VLSDKTLGSGQFGTVYSAIQRHSGKEVA----------------VKVISKERFSKKGSGAESMRAEVAILQ----------------QTCHPGIVCLEFM
    | .|.|.||.|| . ..  .|..|                ||.  ..  ..| .. |..  |  |..                |  || |. .   
YKFIKKIGQGNFGSVYKCKVWKVQKQFAIKIIDQKQQRQQMQEKVKIKIYAMKIMKKNQIEQIKQEIHIMREINCFYKKINEKNILEQLNHPNIIKMYEC

CE--TKDKIFVVMEKMNGDMLEMILS------------------QELGRLNSRATK-------FLLVQILCALKYLHDQG-IAHCDLKPENVLLSDMGSN
 .  ....|. |||  .|  |. ..                   .| ...    ..       | ...|..||.||| .. | | |.||||.|.      
FQEKDDNNIYLVMEYCQGGDLFDYIKNNKKKRNHEIEKDKYFTEKEIKYIMKQILQGFKTKAEFYIACIILALEYLHSKNNIIHRDIKPENILF------

FPQTKICDFGYARFIPES--------------------------------QFRKTVVGTPAYLPPEVLQRKG---------YNKSLDMWSVGVIIYVTLS
    ||.|||..... ..                                .  .|..||| |..||.|..|.         |... |.||.|||.|  |.
---IKIIDFGLSKKYDDDNQNRTHKQQCKWYMFKNDTSRTPGYMDQIIQQNMFNTICGTPGYMAPEILNGKKYDNQQKQKGYDYKCDIWSLGVILYEMLF

GTFPFNEGEEISEQIQNASFMFPTE--------------PWSEVEPLAVDLIQK----LLKVEIEARMS-IEQCLDHGWL
| .||       .||..  . || .               | .... . |||.|    .|... | |.. .||.|.| |.
GKPPF------QQQIKQCKIDFPCPEWQKDTQCIQCKWKSWKKWSQECKDLIKKFGKRMLQKDPEKRITGWEQILNHPWF
Kinase W09C5.5.AA MARK 424-685 32 1.8e-65 213.06 In-house 1-262 (262) Show / Hide 
Range on Protein: 424-685
Range on HMM: 1-262/262
Sequence Identity: 32% (88 aa)

YQVLSDKTLGSGQFGTVYSAIQRHSGKEVAVKVISKERFSKKG-SGAESMRAEVAILQQTCHPGIVCLEFMCE--TKDK-IFVVME-KMNGDMLEMILSQ
| .|  ||.| | ...|. |. .|.|..||.|..  |.|..      .. . |..|...  || |..|  . |  |. . |...||   .|.... | ..
YKML--KTIGHGSYAKVKLACHKHTGRKVAIKIY--EKFKLNDPQWMKNVMREIEIMKKLDHPNIIKLFHVIEQDTEQHQIYLIMEYASGGELYDYIKAH

ELGRLNSRATKFLLVQILCALKYLHDQGIAHCDLKPENVLLSDMG-SNFPQTKICDFGYARFIPESQFRKTVVGTPAYLPPEVLQRKGYN-KSLDMWSVG
. |||  . .. .  ||..|..|.|...|.|.|.||||.|. . |     . ||.|||... ||. |  .|  |||.| .||....| |. .  |.|| |
PNGRLHEEEARRIFRQIVSAVNYCHSKNIVHRDIKPENILIDENGNH---NIKIIDFGFSICIPPGQKLNTFCGTPPYMAPEIFLKKPYDGPKVDIWSLG

VIIYVTLSGTFPFN--E--GEEISEQIQNASFMFPTEPWSEVEPLAVDLIQKLLKVEIEARMSIEQCLDHGWL
|. |. ..|.|||       .|. ..|.. .. .|.     | . . .|||.||.|  | |..||... | |.
VVLYFMVCGYFPFDGDTQDYKELYKKILRGKYDIPCH----VSKECRNLIQRLLTVNPEERPTIEEIMKHPWM
Kinase W09C5.5.AA MAPKAPK 426-685 32 3.1e-65 200.75 In-house 1-292 (292) Show / Hide 
Range on Protein: 426-685
Range on HMM: 1-292/292
Sequence Identity: 32% (96 aa)

VLSDKTLGSGQFGTVYSAIQRHSGKEVAVKVISKERFSKKGSGAESMRAEVAILQQTC-HPGIVCLEFMCET----KDKIFVVMEKMN-GDMLEMILSQE
 |... ||.|  | |  . .. .|.| |||.. .     .|   .  | || .. ..  || ||..    |     ... ..|||.|. |.... | .. 
KLWKEVLGEGIYGKVQTCVHKRTGQEYAVKILEDQ----PGHSRQKARREVELHWHCQGHPNIVQIIDWFENMYQFDKCFYLVMECMEGGELFQHIQQRG

LGRLNSRATKFLLVQILCALKYLHDQGIAHCDLKPENVLLSDMGSNFPQTKICDFGYARF------IPES---QFRKTVVGTPAYLPPEVLQRKG----Y
 .. . |    .  .|  |...||. .||| ||||||.| .|. .| |  |.|||| |        ....   .  .| ..|| | .|||. .      |
HKHFTEREASQIMKDICSAVDFLHSMNIAHRDLKPENILCTDTNHNCP-VKLCDFGFAKEIHLNHDCTTPITTPELMTPCYTPYYMAPEVVGAFKEAHTY

NKSLDMWSVGVIIYVTLSGTFPF--NEG-EEISEQ---------------IQNASFMFPTEPWSEVEPLAVDLIQKLLKVEIEARMSIEQCLDHGWL
.|| |||| |||.|. |.|  ||  | | | .|                 ||.... ||.| ||..   | ||| |||... . |..||| ..| |.
DKSCDMWSLGVIMYIMLCGYPPFYSNCGDEDCSWDRGEACRDCQNMMFHRIQEGQYEFPDEEWSHISEEAKDLIRKLLRRDPTQRLTIEQVMNHPWI
Kinase W09C5.5.AA ULK 426-685 26 4.5e-60 205.9 In-house 1-324 (324) Show / Hide 
Range on Protein: 426-685
Range on HMM: 1-324/324
Sequence Identity: 26% (88 aa)

VLSDKTLGSGQFG-TVYSAIQRHS---GKEVAVKVISKERFSKKGSGAE------SMRAEVAILQQTC---HPG--IVCLEFMCETK--DKIFVVMEKMN
   .. ||.|.|| .|| ..   .   .. ||.|.|.|  ..|| . .|      . . |. |...     ||   ||.|  ..||.  . |. .||  |
YCLNHCLGKGSFGVKVYKGRNKKTNTQNQYVACKMIDKKKMNKKKNEQEGQYMWQLLKNEIQIMKKLKELKHPNHHIVKLYDWFETSNHNNIYIIMEYCN

G-DMLEMILSQEL-------GRLNSRATKFLLVQILCALKYLHDQGIAHCDLKPENVLLSDMGSNF--------PQTKICDFGYARFIPES----QFRKT
| |  . |  .         .||.   ..  . ||. ..|.||...| |.|.||.| |...    .        .. ||.||| |... .     | ..|
GGDLEQYIKKNKKLPETEEKKRLSEQEAIQFFKQICNGFKELHKHNIIHRDIKPQNILIHNGQPKTDSKKVHPNGVLKIADFGFAKHVDNNNMEQQMCQT

VV------GTPAYLPPEVLQ----RKGYN-KSLDMWSVGVIIYVTLSGTFPFNEGEEISEQ----------------IQNASFMFPTEPWSEVE--PLAV
 |      ||| |  |..||    .| |. .  |.||.|.|.|  | |  ||..    ...                |.|  . ||  | ...   |   
CVNEKRIKGTPLYMAPQILQGQGEQKPYYDYKCDIWSLGCIFYEMLYGKYPFFSW-FNDQYLYIQKLINNGKEQQIYIKNQPIQFPKPP-KDPKISPECK

DLIQKLLKVEIEARMSIEQCLDHGWL
|||...|... . |.|.|. ..| |.
DLIRRMLQYDEKDRISWEEIFNHPWF
Kinase W09C5.5.AA RSK 427-685 28 1.3e-59 204.31 In-house 1-278 (278) Show / Hide 
Range on Protein: 427-685
Range on HMM: 1-278/278
Sequence Identity: 28% (79 aa)

LSDK-TLGSGQFGTVYSAIQRHSGKEVAVKVISKERFSKKGSGAESMRAEVAILQQTC-HPGIVCLEFMCETKDKIFVVMEKMNG-DMLEMILSQEL-GR
|... ..| | . ..   ... .|.. |.||..|  . ..   ..  ..|. ||. .  || || |    .|..|.. .|| ..| .... .. ..  | 
LKVLGQGGYGKVFLCRKCTHHDTGQIYAMKVLKKAKIVQRQKDTRHTMTERNILERCQQHPFIVTLHYAFQTEGKLYLIMEYCRGGELFTHLQKEKHFGC

LNSRATKFLLVQILCALKYLHDQGIAHCDLKPENVLLSDMGSNFPQTKICDFGYARF-IPE-SQFRKTVVGTPAYLPPEVLQ----RKGYNKSLDMWSVG
.  .  .| . .| .|...||.||| | ||||||.|. |.  |    |..||| ..   .. .|  .| ..| .|..||.|     ..|..|. | || |
FSEDEACFYMAEIVLAVEHLHQQGIIHRDLKPENILYDDES-NEGHIKLTDFGFCKQFRCDHNQWTMTFCYTIEYMAPEMLKRANQQGGHDKACDWWSLG

VIIYVTLSGTFPFNE-----GEEISEQIQNASFMFPTEPWSEVEPLAVDLIQKLLKVEIEARMS-----IEQCLDHGWL
|..|  |.|  ||        .||...||.. | .. . |... . | |||.|.|... . | .     .|. ..| |.
VLMYEMLTGCPPFQGPNDNNRKEIMKRIQKGKFSLTMPNWQYLSQEAKDLIRKMLHRDPHKRLGCGPQDAEEIKQHPWF
Kinase W09C5.5.AA CAMK1 531-685 38 2.3e-56 162.35 In-house 113-276 (276) Show / Hide 
Range on Protein: 531-685
Range on HMM: 113-276/276
Sequence Identity: 38% (64 aa)

LLVQILCALKYLHDQGIAHCDLKPENVLLSDMGSNFPQTK--ICDFGYARFIPESQ-FRKTVVGTPAYLPPEVLQR---KGYNKSLDMWSVGVIIYVTLS
.  ||| |..|.|..||.|.|||||| |..|.  ...  |  |.||| .... .   . ||..||| |  |||| .   |.| |. ||||.||| |. | 
IMKQILSAVEYMHSKGIVHRDLKPENLLYYDKDEDSK-IKRSIADFGLSKIFDHDENLMKTACGTPGYVAPEVLECKKDKPYDKACDMWSIGVITYILLC

GTFPFNEGE-E--ISEQIQNASFMFPTEPWSE-VEPLAVDLIQKLLKVEIEARMSIEQCLDHGWL
|  ||..   .  . |.| .... ||.  | . .. .| |.| ..|.|. . | ..||||.| |.
GYPPFYDENVDNELFEKIKKCEYEFPSPWWDNISDQEAKDFIKHMLEVDPKKRYTCEQCLNHPWI
Kinase W09C5.5.AA CAMK1 424-505 27 2.5e-16 43.91 In-house 1-88 (276) Show / Hide 
Range on Protein: 424-505
Range on HMM: 1-88/276
Sequence Identity: 27% (25 aa)

YQVLSDKTLGSGQFGTVYSAIQRHS---GKEVAVKVIS-KERFSKKG--SGAESMRAEVAILQQT---CHPGIVCLEFMCETKDKIFVVME
|..  .|..|.| |..|| .... .   ||..|.|.|. |.  .||      |... |..|...     || |. ..   |.....  |||
YEF--GKEIGRGAFSEVYLCTHKETQTNGKQYAIKCIDKKKFMKKKDMQK-QEALENEIEIMKKVSKIDHPNIIKFYEWYESDNHFYLVME
Kinase W09C5.5.AA TyrKc 426-685 21 2.3e-15 25.63 SMART 1-280 (280) Show / Hide 
Range on Protein: 426-685
Range on HMM: 1-280/280
Sequence Identity: 21% (63 aa)

VLSDKTLGSGQFGTVYSAIQRHSGKEVAVKVISKERFSKKGSGAESMRAEVAILQQT--CHPGIVCLEFMCETK-------DKIFVVMEKM-NGDMLEMI
.  .|.||.|.||.|| .. .    .||||.. ..         | .. |  |. .    || ||.|   | ..       . ...||| | .|| .. .
ITLGKKLGEGAFGEVYKGTWK---IQVAVKMLKEDA-------REDFMREARIMCKLGGHHPNIVRLYGVCTQQGRNFMYIEPLMIVMEYMPHGDLKDYL

LSQELGRLNSRATKFLLVQILCALKYLHDQGIAHCDLKPENVLLSDMGSNFPQTKICDFGYARFIPES--------QFRKTV-VGTP-----AYLPPEVL
 . .   |. .      .|| |   |||.... | ||   |.|... .    . ||.||| .|.| .           ||.   |.        ..||..
RKHRPK-LCMKDLLSFCWQIACGMEYLHSKNCIHRDLAARNCLVGENH----TVKISDFGLSRDIYDDDQQGESKDYYRKKEHKGGKTMLPIRWMAPECI

QRKGYNKSLDMWSVGVIIY--VTLSGTFPFN------EGEEISEQIQNASFMFPTEP-----WSEVEPLAVDLIQKLLKVEIEARMSIEQCLDHGWL
. . ..   | || || ..   |. .. . .      . .|. |....   | . .        .  .   .....  . . | | . ...  |  .
NYGKFTTKSDVWSFGVCMWEIFTYGQQPYPGMIQQMMSNQEVIEYVKQGYRMPQPPNDYPMSFVCCPDEMYQIMKQCWHEDPEDRPTFSEI--HECF
Kinase W09C5.5.AA Pkinase_Tyr 426-597 28 8.6e-14 47.34 Pfam 1-177 (270) Show / Hide 
Range on Protein: 426-597
Range on HMM: 1-177/270
Sequence Identity: 28% (53 aa)

VLSDKTLGSGQFGTVYSAIQR----HSGKEVAVKVISKERFSKKGSGA---ESMRAEVAILQQT-CHPGIVCLEFMCE-TKDK--IFVVMEKMNG-DMLE
.  .|.||.|.||.|| .. .      . .||||.. ||   .  . .   |.. .|..|. |   || ||.|   |   ..   |..||| | . |.|.
ITFGKKLGEGAFGEVYKGTWKGDPDNTKIPVAVKML-KE---GAMHEQNCREDFMREAKIMKQLGHHPNIVRLYGVCTDQGEPNQIYIVMEYMPHGDLLD

MILSQ--ELGRLNSRATKFLLVQILCALKYLHDQGIAHCDLKPENVLLSDMGSNFPQTKICDFGYARFIPESQFRKTVVGTPAYLP
   ..  . ..|.        .|| ... ||..... | ||   |.|...   |. . |||||| || | .     ..... . ||
YLRKHREDKQPLTMKDLLQMCWQIAKGMEYLESKNCIHRDLAARNCLVTE---NN-VVKICDFGLARDIYNDDYY-YRKRGGGKLP