Gene Y69E1A.3 (Nematode worm)

Y69E1A.3

Species: Nematode worm
Alias: Y69E1A.3, Y69E1A.c, CE22810, aSWK343
External Links: Wormbase Link ,
Annotation: WormBase Genetic Map location: IV:4.79, WormBase Physical Map location: IV: 10952444-10954606

Classification

Group: TK
Family: Fer

Sequence

Name Sequence Type Origin Length Description Download
Y69E1A.3.AA Protein Genbank 563 None Fasta, JSON
Y69E1A.3.kin_dom Protein Kinase Domain Sugen global kinase HMM prediction 256 Kinase domain by global Sugen HMM Fasta, JSON

Protein domain

Protein domains of Y69E1A.3.AA. The domains are annotated by HMM profiles from Pfam and SMART, as well as in-house data which includes HMMs of each individual kinase group, family and subfamily. Here is domain list in details, including sequence identity, significance and alignment. In particular, you can find can find the best hit kinase group/family/subfamily, which is helpful to understand the relationship between kinases.Kinase domain and best hit kinase group/family/subfamily are highlighted in red and blue. Visualized by pviz.

Usage: Zoom in selected region by dragging mouse and zoom out by double-clicking.

Show/hide domain list
Domain Protein name Domain Name Range Identity (%) Significance Score Profile Source Profile Range (length) Alignment
SH2 Y69E1A.3.AA SH2 92-182 23 3e-14 54.56 SMART 1-87 (87) Show / Hide 
Range on Protein: 92-182
Range on HMM: 1-87/87
Sequence Identity: 23% (23 aa)

LHVYHGVLFGSEAEKLLTW----DRAYLVRRAITKPNKFLCISVNWKNKIFHYQLDFNE-DGWCCKKLYEKFPTMPNRRFLHIRQLLEAWSQATPF
 . ||| . ..|||.|| .    | ..|||   .  ......|| ||.|. ||..  |. .....  .       ..|.|  . .|.. ...    
QPWYHGNISREEAEQLLKNPGMPDGDFLVRDSES-NPGDYVLSVRWKGKVKHYRIRRNDDGKYYIDET-------WRRKFPSL-ELVNHYQHNPLG
SH2 Y69E1A.3.AA SH2 95-176 23 0.00098 12.79 Pfam 2-81 (81) Show / Hide 
Range on Protein: 95-176
Range on HMM: 2-81/81
Sequence Identity: 23% (21 aa)

YHGVLFGSEAEKLLTW----DRAYLVRRAITKPNKFLCISVNWKN---KIFHYQLDFNEDGWCCKKLYEKFPTMPNRRFLHIRQLLEAW
||| . ..|||.||      | ..|||   ..|.    .|| ...   .. ||.  ....|        ..  . ...| .. .| |  
YHGKISRQEAERLLMNPGNPDGTFLVRESESTPGD-YTLSVRDDGPGDRVKHYRIQRTDNG--------GYYITGRHKFCSLQELVEHY
Kinase Y69E1A.3.AA Fer 198-454 36 2.9e-134 452.36 In-house 1-283 (283) Show / Hide 
Range on Protein: 198-454
Range on HMM: 1-283/283
Sequence Identity: 36% (102 aa)

INLDKKLGCGAFGEVFKGQ-----YKAVGSTNPPIEVAVKRILGN-AKRKQIQEFCNEAQIMTV-LQHENIVAFYGFASLEEPIMVVMELVTGGDLRKYF
..|.||||.||||||.||.     .|..........|.||.  .. |...||.||..||.||   ..| |.|.|||....|.|||.|||...||.|..| 
VTLGKKLGEGAFGEVYKGRRTLKCKKGKWHVVNKVAVKVKKCKCEDATKEQIKEFMHEARIMRNNYDHPNVVKFYGVCVDEQPIMIVMEFCNGGSLDSYL

QTTQN--IPKLQILWFAMNVASGMRHLSSKGIIHRDLAARNCLVTQ-DLKAK--ISDFGLSLQ----GTVTTKN--LEKAPIRWLAPESLKSGLFNEKTD
....|  ..  .........|.||..| ||..||||.||||||... ..| |  |||||.| |    |.  ..   ..|.||||||||....|....|||
KKNKNKTVSDNEKIRMCYQAACGMEYLHSKNCIHRDIAARNCLYHKDKVKKKCKISDFGMSRQCSDYGYDYKMKEKACKVPIRWLAPETWQTGIYSPKTD

VWSYGVFLTELMTRCEHDPLY------PKSL-KDAKAWILTEERPHKMKNGDPKELMVLID-ACCERNPNERLNFNTVKRQIT
|||.|| ..| .|........      .. . |.|..|| .......| |..|.|.| ...  |....|..| ......... 
VWSFGVMCWEIFTNGAEPYPGQPHGMKMTNVKKQARKWIIKKGYMMPMPNHMPPEIMQIMMKQCWQKDPEDRPTMKEICQKLK
Kinase Y69E1A.3.AA TyrKc 198-453 33 4.5e-110 372.89 SMART 1-280 (280) Show / Hide 
Range on Protein: 198-453
Range on HMM: 1-280/280
Sequence Identity: 33% (99 aa)

INLDKKLGCGAFGEVFKGQYKAVGSTNPPIEVAVKRILGNAKRKQIQEFCNEAQIMTVL--QHENIVAFYGFASLE-------EPIMVVMELVTGGDLRK
| |.||||.||||||.||..|        |.|||| .  .|    ...|..||.||. |  .|.|||..|| .. .       ||.|.|||.. .|||..
ITLGKKLGEGAFGEVYKGTWK--------IQVAVKMLKEDA----REDFMREARIMCKLGGHHPNIVRLYGVCTQQGRNFMYIEPLMIVMEYMPHGDLKD

YFQTTQN-IPKLQILWFAMNVASGMRHLSSKGIIHRDLAARNCLVTQDLKAKISDFGLSLQGTVT--------TKN-----LEK--APIRWLAPESLKSG
| . ... ..  . | |.  .|.||..|.||..||||||||||||. .. .||||||||  ..          ..       .|   ||||.|||... |
YLRKHRPKLCMKDLLSFCWQIACGMEYLHSKNCIHRDLAARNCLVGENHTVKISDFGLSRDIYDDDQQGESKDYYRKKEHKGGKTMLPIRWMAPECINYG

LFNEKTDVWSYGVFLTELMTRCEHDPLYP----KSLKDAKAWILTEERPHKMKNG-------DPKELMVLIDACCERNPNERLNFNTVKRQI
 |..|.||||.|| . |..|...  .  .    .| ... ... . .|. ...|.        |.|.  ..  |....|..| .|.......
KFTTKSDVWSFGVCMWEIFTYGQQPYPGMIQQMMSNQEVIEYVKQGYRMPQPPNDYPMSFVCCPDEMYQIMKQCWHEDPEDRPTFSEIHECF
Kinase Y69E1A.3.AA Pkinase_Tyr 198-453 37 1.2e-98 334.7 Pfam 1-270 (270) Show / Hide 
Range on Protein: 198-453
Range on HMM: 1-270/270
Sequence Identity: 37% (101 aa)

INLDKKLGCGAFGEVFKGQYKAVGSTNPPIEVAVKRILGNAKRKQ--IQEFCNEAQIMTVL-QHENIVAFYGFAS-LEEP--IMVVMELVTGGDLRKYFQ
| ..|||| ||||||.|| .|     |. |.|||| .  .|  .|  ...| .||.||. | .|.||| .||  .  .||  |..|||.. .|||..| .
ITFGKKLGEGAFGEVYKGTWKG-DPDNTKIPVAVKMLKEGAMHEQNCREDFMREAKIMKQLGHHPNIVRLYGVCTDQGEPNQIYIVMEYMPHGDLLDYLR

T----TQNIPKLQILWFAMNVASGMRHLSSKGIIHRDLAARNCLVTQDLKAKISDFGLSLQG-----TVTTKNLEKAPIRWLAPESLKSGLFNEKTDVWS
.     |...  ..| ... .|.|| .|.||..||||||||||||| ....||.||||.         ....   | ||.|.|||... | |..|.||||
KHREDKQPLTMKDLLQMCWQIAKGMEYLESKNCIHRDLAARNCLVTENNVVKICDFGLARDIYNDDYYYRKRGGGKLPIKWMAPECINYGKFTTKSDVWS

YGVFLTELMTRCEHDP-LYPKSLKDAKAWILTEERPHKMKNGDPKELMVLIDACCERNPNERLNFNTVKRQI
.|| . |..|..|  |  .  |  . ...|  . .  ..  . |.|.  |.  | . .|..|  |  . .|.
FGVLMWEIFTYGE-QPTYPGMSNEEVYEYIYEDGYRMPCPENCPDEIYDLMKQCWHYDPEDRPTFSEIHEQL
Kinase Y69E1A.3.AA TK 198-453 19 4.8e-87 291.76 In-house 1-486 (486) Show / Hide 
Range on Protein: 198-453
Range on HMM: 1-486/486
Sequence Identity: 19% (96 aa)

INLDKKLGCGAFG---EVFKGQYKAVG--------------------STNPPIEVAVKRIL---GNAKRKQIQ----------EFCNEAQIMTVLQ----
| | |||| |.||   ||.||...  .                    ... ...|||| .    ..... ...          .|..||..| ...    
ITLGKKLGEGQFGSFGEVYKGEWRGRNPWNGKRFPCHMTVTLKCKNGKEGGKTPVAVKMLKEGDAMSQEEFFDEEMHDRDGGEDFLEEAEEMKMMCHSLG

-HENIVAFYG-------------FASLEEPIMVVMELVTGGD----LRKYFQTTQN--------------------------------------------
 |.||| .||             . ...||.|.|||.. .||    ||.| ..  .                                            
HHPNIVRLYGVCTQGEPKPCFEVV-VHQEPWMIVMEYMPHGDMDGSLRDYLRKCRPKFQHEQDCPDNQHNKYPPSKLHHCMKGDITYSHESNSPCPEEQD

--------------------------------IPKLQILWFAMNVASGMRHLSSK------GIIHRDLAARNCLVTQDLK-----------AKISDFGLS
                                ..  | | ... .|.||..|.||      ...|||||||||||.....           .||.|||||
YDDDLIKDHPPPLTTKDLLQMAWQWCLTCKHQLTMHQLL-MCWQIACGMEYLHSKNCEFIQNFVHRDLAARNCLVGENNVCKWHFDGCGPVCKIADFGLS

------LQGTV------TTKN------------------------LEKAPIRWLAPESLKSGL---------FNEKTDVWSYGVFLTELMTRCEHDPLYP
      |   .      ..|.                          | ||||.|||.|...          | .|.||||.||.. |..|...  .   
RQGSGVLARDIYSDDDYYRKSSYGTGRPMWPFEDDPWQDYYRQQSGGKLPIRWMAPECLNDRVFSEAEKYGKFTTKSDVWSFGVLMWEIFTYGQEPYYGG

KSL---------KDAKAWILTEERP-----------HKMK--NGDP--------------KELMVLIDACCERNPNERLNFNTVKRQI
 |          ..    . .. |.           . |.   . |              .|.. |.  |....|..| .| ....|.
MSNQDVWKDGDNQEVMEYLRRGGRLCRSGLNEVGYRMRMPQPPHCPDWMRYRMHPPHCPPEEYYDLMQQCWHYDPEDRPTFSQLHEQL
Kinase Y69E1A.3.AA UTK 198-393 32 1.5e-61 209.35 In-house 1-236 (296) Show / Hide 
Range on Protein: 198-393
Range on HMM: 1-236/296
Sequence Identity: 32% (77 aa)

INLDKKLGCGAFGEVFKGQYKAVGSTNPPIEVAVKRIL-GNAKRKQIQ---EFCNEAQ---IMTVLQ-HENIVAFYGFASLEEPIMVVMELVTGGDLRKY
. | ..|| ||||||.|. .. .    .   ||||    . .....     .| .||.   .|  .. |.|.. ..|  . |||.|.|.|.  .||||.|
VQLGRQLGQGAFGEVHKARFTQCSEHMYEMDVAVKVCQHHADAQQEPEPYPDFMEEARELQMMKQFHWHPNVLRLVGVCTQEEPWMIVTEYMENGDLRSY

FQTTQNIP--------KLQILWFAMNVASGMRHLSSKGIIHRDLAARNCLVTQD-------LKAKISDFG---LSLQGT-------------VTTKNLEK
 ..    |        . | | .|...|.|| .|.|.|..|||||||||||...       ...||.|||   .| .               ..  . ..
LRRHRPTPPACPHWLTLHQRLCMAWDIARGMQYLHSCGFVHRDLAARNCLVHMHRMMWHCMMVCKIADFGRGGMSRRVNTFHFSNRYWESYYYMAQHQDR

APIRWLAPESLKSG-LFNEKTDVWSYGVFLTELMTR
.|||| |||.| ..  | .|.||||.||.. |..|.
WPIRWMAPEALTHHTRFTTKSDVWSFGVVCWEIWTW
Kinase Y69E1A.3.AA TK-Unique 198-392 33 2.8e-59 203.02 In-house 1-234 (294) Show / Hide 
Range on Protein: 198-392
Range on HMM: 1-234/294
Sequence Identity: 33% (79 aa)

INLDKKLGCGAFGEVFKGQYKAVG-STNPPIEVAVKRILGNAKRKQIQEFCNEAQIMTVLQ-HENIVAFYGFASLE-EPIMVVMELVTGGDLRKYFQTTQ
.......| ||||.|..|... .  . . .. ||||    ||   . |.| .|.|.|  |  |.||| ..|      || | .|| . .|.|..|..|..
LEVGDVIGEGAFGQVWRGEVWGIWKHWDKQKCVAVKMLKDNATDTDKQDFLKEIQMMKELGDHPNIVQCLGCCTKSDEPWMIIMEYCPCGNLQHYLRTCR

-N-------------------------IPKLQILWFAMNVASGMRHLSS--KGIIHRDLAARNCLVTQDLKAKISDFGLS--LQ-GTVTTKNLE--KAPI
 .                         |   . . ||  .|.|| .|.|  |.|.||||.|||.|.| |...||.|||..  .. ..|. .. .  . ||
PAMRQHQTYGNLKFDFHHMPDKPRTEPISPKDLYHFAWQIACGMEYLASQRKKIVHRDLCARNVLLTEDKVCKICDFGMARDVYTNGVYSMMCSQGRIPI

RWLAPESLK--SGLF-NEKTDVWSYGVFLTELMT
||.||||||   | . ..|.||||.||.. |..|
RWMAPESLKCYHGMYHTTKSDVWSFGVLMWEIFT
Kinase Y69E1A.3.AA Src 198-393 38 7e-58 195.21 In-house 1-196 (255) Show / Hide 
Range on Protein: 198-393
Range on HMM: 1-196/255
Sequence Identity: 38% (79 aa)

INLDKKLGCGAFGEVFKGQYKAVGSTNPPIEVAVKRILGNAKRKQIQEFCNEAQIMTVLQHENIVAFYGFASLEEPIMVVMELVTGGDLRKYFQ---TTQ
| | .||| | ||||..| ..        ..|||| .       . . |  |||||. |.||..|. |   | ||||  | |. . | | .| .   ...
IKLCRKLGQGQFGEVWMGYWNGN------TKVAVKTLKPGT--MSPEAFLQEAQIMKKLRHEKLVQLYAVCSQEEPIYIVTEYMSHGSLLDYLKKDGEGR

NIPKLQILWFAMNVASGMRHLSSKGIIHRDLAARNCLVTQDLKAKISDFGLS--LQ-G--TVTTKNLEKAPIRWLAPESLKSGLFNEKTDVWSYGVFLTE
...  | . .|  ||.||  |.|. .||||||||| || ... .|. ||||   .. .    . .   | ||.| ||| .  | |. |.||||.|. |||
HLHLPQLIDMAAQVAEGMAYLESMNYIHRDLAARNVLVGENNVCKVADFGLARLIKEDDDEYCARHGAKFPIKWTAPEAINYGRFTIKSDVWSFGILLTE

LMTR
..|.
IVTY
Kinase Y69E1A.3.AA TKL 204-453 21 1.8e-57 197.25 In-house 1-364 (364) Show / Hide 
Range on Protein: 204-453
Range on HMM: 1-364/364
Sequence Identity: 21% (82 aa)

LGCGAFGEVFKGQYKA---VGSTNPP----IEVAVKRILG---NAKRKQIQE---------------------FCNEAQIMTVLQ--HENIVAFYGFASL
.| |.||||.||...    ..    |     .||||..     . . |..||                     |. | .||  ..  |.||| |.|..  
IGSGGFGEVYKGKWRGWGGKC----PSDTGKDVAVKKFKSHNDDEFTKNSQENNDNNNYSDMQLNDPEASWFRFFEEEEIMMMSRLRHPNIVQFMGYCCC

EEP-------------IMVVMELVTGGDLRKYFQTTQNIPKLQILWFAMNVASGMRHLSS--------KGIIHRDLAARNCLVTQDLK------------
...             .. |||.. ||.|. |..        |.. .|. .|.|| .| |        ..||||||  .|.|| ....            
PPCGCVCMHPVGPWGQLCIVMEYCPGGSLLHYLH------WHQRCRWALDIARGMNYLHSMNPKWCTKPPIIHRDLKSKNILVDENWTNVSNYMYNPNAD

--AKISDFGLSLQGTVT---------------------TKNLEKAPIRWLAPESLK----------------SGLFNEKTDVWSYGVFLTELMTRC--EH
  .||.|||||   . .                     |.. .   .||.||| |.                .. ..||.||.|.|. | |..|||  ..
WCCKICDFGLSRFMSQSGNMNDTMTTMMESAEHQNNRKTTMTQCGTPRWMAPEVLRGQMNYTEKVGIDEFCKGFEYSEKCDVYSFGIVLWEILTRCRPYY

DPLYPKSL-----KDAKAWILTEERPHKMK------------NGDPKELMVLIDACCERNPNERLNFNTVKRQI
|. |.  .     ..  ...  . ..  ..            .  |...  |.  |.. .|..|..|.... ..
DYPYMPMIFQDPFEEMFMMVCDKGLRPPIPPIWQNHHKMCPCPDCPPSMKKLMQDCWDHDPEKRPSFQEILKRL
Kinase Y69E1A.3.AA RTKB 198-385 35 3.9e-50 167.21 In-house 1-198 (264) Show / Hide 
Range on Protein: 198-385
Range on HMM: 1-198/264
Sequence Identity: 35% (70 aa)

INLDKKLGCGAFGEVFKGQYKAVGSTNPPIEVAVKRILGNAKRKQIQEFCNEAQIM-TVLQHENIVAFYGFASLEEPIMVVMELVTGGDLRKYFQ---TT
. |..||| |||||||.....  .. |    .|.|.. . |   . |.|| |  .| .. .| |..   |    .|| ..  ||   | || |     ..
VWLGEKLGNGAFGEVFQAWVRNRHM-NTEQSCAAKVLKPGASYEERQDFCSEMTVMKELGWHPNVIGIIGHCLQDEPYILLVELCELGNLRDYLRMCRAS

QNIPK----LQILWFAMNVASGMRHLSSKGIIHRDLAARNCLVTQDLKAKISDFGLSL--QGTVTTKNLEKAPIRWLAPESLKSGLFNEKT-DVWSYGV
|  |      | . |.. .|.|| .|.....|||||.||| ||.|.|. ||.|||..   ..   .. . . ||.|.||||...  .. |  ||||.||
QHNPQSLKQAQLVDFCHQIACGMAFLHQHNVIHRDLCARNVLVDQQLHCKICDFGMAREIDHECYETTCTRLPIKWMAPESWAHRIYTTKSGDVWSFGV
Kinase Y69E1A.3.AA Csk 198-390 38 3.7e-49 165.89 In-house 1-190 (251) Show / Hide 
Range on Protein: 198-390
Range on HMM: 1-190/251
Sequence Identity: 38% (77 aa)

INLDKKLGCGAFGEVFKGQYKAVGSTNPPIEVAVKRILGNAKRKQIQEFCNEAQIMTVLQHENIVAFYGFASLEEP--IMVVMELVTGGDLRKYFQT--T
. | .. | | || |  |.|.          |||| | ...    .| |  || .|| |.|.| |.. |   |...  . .||| .  | |  |  .   
LHLGECIGHGEFGDVMQGEYQNR-------KVAVKCIKCDG-NGMAQAFLAEASVMTQLRHPNLVQLIGVI-LHQKNHLYIVMEYMSKGNLVDYLRSRGR

QNIPKLQILWFAMNVASGMRHLSSKGIIHRDLAARNCLVTQDLKAKISDFGLSLQGTVTTK--NLEKAPIRWLAPESLKSGLFNEKTDVWSYGVFLTEL
. | . | | ||| |..||  | .| ..|||||||| ||  |. ||.|||||. . . .       | || | ||| |. . |  | ||||.|..| |.
HVITRRQLLKFAMDVCEGMCYLEQKKFVHRDLAARNILVSEDCVAKVSDFGLAKEECSQQDDSTSGKFPIKWTAPEALRHKKFSTKSDVWSFGILLWEI
Kinase Y69E1A.3.AA Src-Unclassified 242-392 34 7.8e-40 134.24 In-house 48-222 (284) Show / Hide 
Range on Protein: 242-392
Range on HMM: 48-222/284
Sequence Identity: 34% (61 aa)

QIQEFCNEAQIMTVLQHENIVAFYGFASLEEPIMVVMELVTGGDLRKYFQTTQ-NIPKLQIL-------------WFAMNVASGMRHLSSKGIIHRDLAA
.|  || |||||. ..| |.|. |.  | |||. .. |. . | |  . ..     . .| .               |  |||||  |.||...||||||
KILNFCQEAQIMKKCRHQNLVHLYAVCSQEEPYYIITEYMINGSLLQWLREGGGQYLHIQDMSEETGRKNVLIGVDIAAQVASGMMYLESKKYVHRDLAA

RNCLVTQDL-----KAKISDFGLS-----LQGTVTTKNLEKAPIRWLAPESLKSGLFNEKTDVWSYGVFLTELMT
|| |.          .|. ||||             .   . |. | |||    | |. |.||||||. | |.||
RNVLIGHNNSNGVPVVKVCDFGLARKKLMQDDNYCMRTGAMFPWKWMAPECFIYGNFSIKSDVWSYGILLWEIMT
Kinase Y69E1A.3.AA S_TKc 198-458 24 2.8e-39 137.72 SMART 1-231 (231) Show / Hide 
Range on Protein: 198-458
Range on HMM: 1-231/231
Sequence Identity: 24% (66 aa)

INLDKKLGCGAFGEVFKGQYKAVGSTNPPIEVAVKRILGNAKRKQIQEFCNEAQIMTVLQHENIVAFYGFASLEEPIMVVMELVTG--GDLRKYFQTTQN
  . .|.| ||||.|.|.. |         .||.|.|         . ...| ||.   .|.||| .|..    . . .|||.. |  |||..| .  . 
YEILRKIGKGAFGKVYKCRHKK-----TGRIVAIKIIK--------EHIRREIQILKK-HHPNIVKLYDVFQD-DHLYMVMEYCDGDLGDLFDYIKKRGR

------IPKLQILWFAMNVASGMRHLSSKGIIHRDLAARNCLVTQDLKAKISDFGLSLQGTVTTKNLEKAPIRWLAPESLKSGLFNE-KTDVWSYGVFLT
      .|  ..  ..  ..... .. |.|||||||   | |...    ||.||||. |      .       ..||| |    ..  | |.|| |. | 
HGLRFPFPE-HARFYMYQICCALEYCHSHGIIHRDLKPENILLDE--HIKICDFGLARQL-----TTFCGTPWYMAPEVL---GYGKCKCDWWSCGCILY

ELMTRCEHDPLYPKSLKDAKAWILTEERPHKMKNGDPKELMVLIDACCERNPNERLNFNTVKR----QITDIYM
|.....   |..|  ..     |.            ..|.  .|. |....|..|.    . .       . ..
EMLCGY---PPFP-QMQMMFKKIG------------SPEAKDFIRKCLQKDPEKRPTA-EALQDEWDIKCHPWF
Kinase Y69E1A.3.AA Trk 198-346 38 7.5e-39 129.28 In-house 1-164 (275) Show / Hide 
Range on Protein: 198-346
Range on HMM: 1-164/275
Sequence Identity: 38% (64 aa)

INLDKKLGCGAFGEVFKGQYKAVGSTNPPIEVAVKRILGNAKRKQIQEFCNEAQIMTVLQHENIVAFYGFASLEEPIMVVMELVTGGDLRKYFQT-----
| | . || |||| || .. .    .. .. ||||  | .|  .  ..|  ||...| |||..||.|||    ..|.. | |    |||.|| .      
IVLKWELGEGAFGKVFLAECYNLCPEQDKMMVAVK-TLKDASENARKDFQREAELLTNLQHQHIVKFYGVCTDHDPLLMVFEYMKHGDLNKYLRQHGPDA

---TQNIP--------KLQILWFAMNVASGMRHLSSKGIIHRDLAARNCLVTQDLKAKISDFGLS
   .|. |          |.|| |  .||||  . |  ..|||.|.||||| |.|  ||.|||.|
MCYAQYQPRQAPGPLTIDQMLWIAKQIASGMVYMASQHFVHRDMATRNCLVGQNLIVKIGDFGMS
Kinase Y69E1A.3.AA Pkinase 198-453 22 2.7e-31 111.72 Pfam 1-293 (293) Show / Hide 
Range on Protein: 198-453
Range on HMM: 1-293/293
Sequence Identity: 22% (69 aa)

INLDKKLGCGAFGEVFKGQYKAVGSTNPPIEVAVKRILGNAKRK-QIQEFCN--EAQIMTVLQHENIVAFYGFASLEEPIMVVMELVTGG----DLRKYF
. . .|.| |.||.|.|.. |  |      .||||.|    ... . |.  .  |.|||  |.|.||| .|..   .  | .|||.. ||    ||  | 
YHIGRKIGSGSFGCVYKCHHKGTGK-----IVAVKIIKKRHEKSWKDQTHRRLSEIQIMKRLNHPNIVRLYDWFEDKDHIYMVMEYCEGGLYVMDLFDYI

Q--TTQNI--PKLQILWFAMNVASGMRHLSSKGIIHRDLAARNCLVTQDLKA----KISDFGLSL---QGTVTTKNLEKAPIRWLAPESLK-SGLFNEKT
.     ..  .  ..  ..  ...|. .. |.|||||||   |.|. ..       ||.||||.        .  .     ....||| .. .     | 
STWRHGCFYFSEWECKFYMYQILRGLEYCHSMGIIHRDLKPENILIDNNGHIDACVKICDFGLAKQFDY-NNS-MTTFCGTPWYMAPEVIRGGQYYGPKV

DVWSYGVFLTELMTRCEHDPLYPKS----LKDAKAWILTEERPHKMKNGDP-----------------------KELMVLIDACCERNPNERLNFNTVKR
|.||.|. | |....    |..| .      . . ... . .. . .   |                       .|.  .|. |....|..|...  .. 
DMWSCGCILYEMLCGR---PPFPGHCWHDN-HDQMQMICRIMGPPLHFDWPWWCSISYFFFRHWHFHWTFHNWSEECKDFIKWCLCKDPKKRPTAEQILQ

Q--I
   .
HPWF
Kinase Y69E1A.3.AA Trk 360-453 29 4.9e-10 30.14 In-house 183-275 (275) Show / Hide 
Range on Protein: 360-453
Range on HMM: 183-275/275
Sequence Identity: 29% (28 aa)

PIRWLAPESLKSGLFNEKTDVWSYGVFLTELMTRCEHDPLYPKSLKDAKAWILTEER-PHKMKNGDPKELMVLIDACCERNPNERLNFNTVKRQI
||||. |||  .  |    ||||.|| . | .|     | |  | . .  .|.     . . .   |.|.  .   |  | | .|.|   .   |
PIRWMPPESIMYRKFTYESDVWSFGVVMWECFTYG-KQPWYQLSNHEVIECIHQGRHRLERPRRC-PQEVYDIMLGCWQREPQQRMNIKDIHDII
Kinase Y69E1A.3.AA Src-Unclassified 198-232 40 7.8e-08 22.88 In-house 1-29 (284) Show / Hide 
Range on Protein: 198-232
Range on HMM: 1-29/284
Sequence Identity: 40% (14 aa)

INLDKKLGCGAFGEVFKGQYKAVGSTNPPIEVAVK
. | .||| | ||||..| ..        ..||||
VHLLRKLGRGQFGEVWYGKWRGK------VDVAVK
Kinase Y69E1A.3.AA UTK 434-453 30 0.045945 2.86 In-house 277-296 (296) Show / Hide 
Range on Protein: 434-453
Range on HMM: 277-296/296
Sequence Identity: 30% (6 aa)

ACCERNPNERLNFNTVKRQI
.|.. .| || .| ..  |.
RCWHYDPQERPDFEDLVQQM