Gene ZC373.4 (Nematode worm)

ZC373.4

Species: Nematode worm
Alias: ZC373.4, CE02377, aSWK059
External Links: Wormbase Link ,
Annotation: WormBase Genetic Map location: X:1.64, WormBase Physical Map location: X: 10073521-10066225

Classification

Group: CAMK
Family: MLCK

Sequence

Name Sequence Type Origin Length Description Download
ZC373.4.kin_dom Protein Kinase Domain Sugen global kinase HMM prediction 256 Kinase domain by global Sugen HMM Fasta, JSON
ZC373.4.AA Protein Genbank 1211 None Fasta, JSON

Protein domain

Protein domains of ZC373.4.AA. The domains are annotated by HMM profiles from Pfam and SMART, as well as in-house data which includes HMMs of each individual kinase group, family and subfamily. Here is domain list in details, including sequence identity, significance and alignment. In particular, you can find can find the best hit kinase group/family/subfamily, which is helpful to understand the relationship between kinases.Kinase domain and best hit kinase group/family/subfamily are highlighted in red and blue. Visualized by pviz.

Usage: Zoom in selected region by dragging mouse and zoom out by double-clicking.

Show/hide domain list
Domain Protein name Domain Name Range Identity (%) Significance Score Profile Source Profile Range (length) Alignment
Kinase ZC373.4.AA MLCK 45-300 53 6.7e-217 578.49 In-house 1-257 (257) Show / Hide 
Range on Protein: 45-300
Range on HMM: 1-257/257
Sequence Identity: 53% (138 aa)

YQVTKLLGDGKFGKVYCVIEKETGKEFAAKFIKIRKEADRAEVEREVSILTQLRHPRIAQIYDAFYTTTNDVVLIMEIVRGGELFDRVAEESYVLSELAV
||....||.|||| |...|||.|||..||||||.||..|...|..|..|..||.||.. |..|||.|.. ..|.|||...|||||.|. .|...|.|. |
YQIHEELGRGKFGIVHRCIEKSTGKTWAAKFIKCRKPKDKENVKNEIEIMNQLHHPNLIQCHDAFETKN-EMVMIMEYISGGELFERIVDEDFHLTEREV

VMIICQLCEAIDYIHKQNILHLDVKPENIMCVSLTGNRIKLIDFGLARHYDGTQE-LKYMAGTPEFAAPEVIKFEKLDYHTDMWSIGVITYILLSGYSPF
.....|.||.....|.|||.|||.|||||||.. |...||.|||||||.||. .. .|.| |||||.||||.........|||||.|||.|.||||.|||
IHYMRQICEGVHHMHWQNIVHLDLKPENIMCQTRTSHQIKIIDFGLARKYDPDEKKVKVMFGTPEFVAPEVVNYDPVGFQTDMWSVGVICYMLLSGLSPF

LGDNLGETYCNVEKGVWEFT-EEFDTVTEEAKDFVTKLLVYDQSKRMLPHECLQHPWI
.||| .||..||... |.|  |.|| ...|||||...|||.|..|||  ||||||||.
MGDNDRETMNNVTSCEWDFDDECFDDISDEAKDFISRLLVKDKEKRMTAHECLQHPWL
Kinase ZC373.4.AA DAPK 47-300 46 1.8e-120 333.58 In-house 1-264 (264) Show / Hide 
Range on Protein: 47-300
Range on HMM: 1-264/264
Sequence Identity: 46% (122 aa)

VTKLLGDGKFGKVYCVIEKETGKEFAAKFIKIRK-EAD-----RAEVEREVSILTQLR-HPRIAQIYDAFYTTTNDVVLIMEIVRGGELFDRVAE-ESYV
  . || |.|  |  ...|.|||..|||||| |.  ..     |.| |.|..|| ..| ||..    ... |.| ||.|| | | |||||| ..|     
MGEELGRGQFAVVRKCRHKSTGKHYAAKFIKKRRRGQSRRGVCREEIEHEIAILEECRGHPNVINLHEVYETRT-DVILILEYVSGGELFDYCCEDREEC

LSELAVVMIICQLCEAIDYIHKQNILHLDVKPENIMCVS-LTGN-RIKLIDFGLARHYDGTQELKYMAGTPEFAAPEVIKFEKLDYHTDMWSIGVITYIL
|.|  ..  . |  |.. | | .|| ||| ||.|||  .  . . .||.|||||.|  .   |.. ..||||. |||.. .| |   ||||||||||||.
LCEEDATRFMKQILEGVHYLHSRNICHLDLKPQNIMLTDRNIPQGDIKIIDFGLSRKICNGEEFRDIMGTPEYVAPEIVNYEPLSLATDMWSIGVITYIM

LSGYSPFLGDNLGETYCNVEKGVWEFTEE-FDTVTEEAKDFVTKLLVYDQSKRMLPHECLQHPWI
||| ||||||.  ||. |. .   .| || |. . |.||||  .||| |  |||   ||||||||
LSGISPFLGDTKQETFLNISQVNYDFSEEYFSCTSEHAKDFIRRLLVKDPEKRMTAEECLQHPWI
Kinase ZC373.4.AA CAMK 50-300 24 3.9e-114 369.31 In-house 1-425 (425) Show / Hide 
Range on Protein: 50-300
Range on HMM: 1-425/425
Sequence Identity: 24% (103 aa)

LLGDGKFGKVYCVIEKETG------------KEFAAKFIKIR----------------------------KEADRAEVEREVSILTQ-------LRHPRI
 || | ||||. .|.|.|.            ...|.|.|. .                            .. ||..|.||..|. .       |.|| |
TLGRGSFGKVKLCIHKNTTGKERVHHIYTNGQKVAIKIIDKKKLKDKQNQDYSNCYKIDKSKCKHRYCWRRPKDRKNVRREIEIMKKLQGIGNKLDHPNI

AQIYDAFYT-----------TTND--------VVLIM---EIVRGGEL----FDRVAEESY--------------VLSELAVVMIICQLCEAIDYIHKQN
 ..|... .           | ..        ....|   | . ||||    ||.. | ..               ..|  .  .. |.|.|..|.|..|
IKLYEVYEDPHYFKNTNDYET-SKQVFTKDKHMYMVMEIMEYCSGGELFDDLFDYIVEHGCYGEEFDQFDIVERGRFTEREARRYFRQICSAVHYCHSHN

ILHLDVKPENIMCVSLTG---------------NRIKLIDFGLARHYDG------------------------TQELKYMAGTPEFAA-PEVIKF-----
| |.| |||||....  .               | ||.||||.|...|.                        .| .| . ||||..| |||..      
IVHRDLKPENILLDDNNDDSDPVEHDEIFDWNNNNIKIIDFGFANKFDPGENNFMCSDYKGGEMHNQWTTPTEGQKMKTFCGTPEYMAAPEVLNGKGHCN

---------EKLDYHTDMWSIGVITYILLSGYSPFLGD-------------NLGETYCNVEKGVWEFTEEFDT-------------VTEE--------AK
         .  .. .||||.|||.||.|.||.|| ||             |. |.. .. || ..| ... .             ...|        .|
MQNATDEEKPYYGPKCDMWSCGVILYIMLCGYPPFYGDCDNEICEDEWIGMNDYELFEKIMKGKYDFPPPYFSPISCNYGPEWWDDISDEFHHFVSQECK

DFVTKLLVYDQSKRMLPHECLQHPWI
|.. |.|..| .|||  ..||.|||.
DLIRKMLQVDPEKRMTIEQCLNHPWM
Kinase ZC373.4.AA DAPK 45-300 48 3.4e-112 324.92 In-house 1-264 (264) Show / Hide 
Range on Protein: 45-300
Range on HMM: 1-264/264
Sequence Identity: 48% (129 aa)

YQVTKLLGDGKFGKVYCVIEKETGKEFAAKFIKIRKEA------DRAEVEREVSILTQLR-HPRIAQIYDAFYTTTNDVVLIMEIVRGGELFDRVAEESY
|..   .| | |  |  . || ||||.|||||| |. .       | ..||||||| ..| || |    |.. . | ||||| | | |||||| ..|.  
YDMGEEIGSGQFAVVKKCREKSTGKEYAAKFIKKRRYTASRRGVSREDIEREVSILREIRGHPNIITLHDVYENKT-DVVLILELVSGGELFDFLCEKE-

VLSELAVVMIICQLCEAIDYIHKQNILHLDVKPENIMCVSLTGNR--IKLIDFGLARHYDGTQELKYMAGTPEFAAPEVIKFEKLDYHTDMWSIGVITYI
 |.|      | |  ... ..|  .| |.| ||||||          ||.||||||.  .  .| | . ||||| |||.. .| |   ||||||||||||
CLNEEEATQFIKQILDGVHHMHSKHICHFDLKPENIMLLDRNVPNPRIKIIDFGLAHRIEPGNEFKNIFGTPEFVAPEIVNYEPLGLETDMWSIGVITYI

LLSGYSPFLGDNLGETYCNVEKGVWEFTEEFDTVT-EEAKDFVTKLLVYDQSKRMLPHECLQHPWI
|||| ||||||.  ||  |.     .| ||.   | | ||||. .||| |  |||   ||||||||
LLSGASPFLGDTKQETLANITAVNYHFDEEYFKNTSEHAKDFIRRLLVKDPKKRMTIQECLQHPWI
Kinase ZC373.4.AA Trio 45-300 37 3.3e-100 257.46 In-house 1-258 (258) Show / Hide 
Range on Protein: 45-300
Range on HMM: 1-258/258
Sequence Identity: 37% (98 aa)

YQVTKLLGDGKFGKVYCVIEKETGKEFAAKFIKIRKEADRAEVEREVSILTQLRHPRIAQIYDAFYTTTNDVVLIMEIVRGGELFDRVAEESYVLSELAV
| ..  .| | |. |  ...| ||...|||||  | . |.. | .| ..|  |.||....  |.. | .   .|| |   .||| ..... . ...|  |
YTFQEEIGRGRFSVVRRCWHKATGRTCAAKFIPYRMM-DKEQVYHEYEMLQHLQHPCVCSLHDTYETPRH-YILILELCDDGELLCCLMRWG-SYCESEV

VMIICQLCEAIDYIHKQNILHLDVKPENIMCVSLTG--NRIKLIDFGLARHYDGT--QELKYMAGTPEFAAPEVIKFEKLDYHTDMWSIGVITYILLSGY
   . |. ||..| | . |||||.||||.| .   .   .||..||| |  ....    .    |.|||.|||.|. .  .| || |||||.||..|||.
KTYMWQMLEAVHYLHNCHILHLDIKPENMMMWHYNAGRPQIKICDFGDAQQLWPHKVEPQHHQYGNPEFMAPEIIQGNPVSYGTDIWSIGVLTYVMLSGI

SPFLGDNLGETYCNVEKGVWEFTEEFDT-VTEEAKDFVTKLLVYDQSKRMLPHECLQHPWI
|||..... ||  |. .|   | |.    | ..||.|..|.|. | .||    ||||||| 
SPFYDESDRETCMNICRGDFSFPECYFCHVSQNAKHFICKVLQEDPWKRPCASECLQHPWF
Kinase ZC373.4.AA S_TKc 45-300 32 3.4e-95 323.46 SMART 1-231 (231) Show / Hide 
Range on Protein: 45-300
Range on HMM: 1-231/231
Sequence Identity: 32% (88 aa)

YQVTKLLGDGKFGKVYCVIEKETGKEFAAKFIKIRKEADRAEVEREVSILTQLRHPRIAQIYDAFYTTTNDVVLIMEIVRG--GELFDRVAEESYV----
|.. ...| | |||||....|.||...| | ||         ..||..|| . .|| | ..||.|..  ... ..|| . |  |.|||.  .  .     
YEILRKIGKGAFGKVYKCRHKKTGRIVAIKIIK-------EHIRREIQILKK-HHPNIVKLYDVFQD--DHLYMVMEYCDGDLGDLFDYIKKRGRHGLRF

-LSELAVVMIICQLCEAIDYIHKQNILHLDVKPENIMCVSLTGNRIKLIDFGLARHYDGTQELKYMAGTPEFAAPEVIKFEKLDY-HTDMWSIGVITYIL
 ..|  .  ...|.|.|..|.|...|.| |.|||||.. .    .||..||||||..      . . |||.. ||||.   . ..   |.||.|.| |..
PFPE-HARFYMYQICCALEYCHSHGIIHRDLKPENILLDE----HIKICDFGLARQL------TTFCGTPWYMAPEVL---GYGKCKCDWWSCGCILYEM

LSGYSPFLGDNLGETYCNVEKGVWEFTEEFDTVTEEAKDFVTKLLVYDQSKRMLPHECLQ-------HPWI
|.|| ||   .. ... ..              ..|||||. |.|..| .||.   |.||       |||.
LCGYPPFP--QMQMMFKKIG-------------SPEAKDFIRKCLQKDPEKRPTA-EALQDEWDIKCHPWF
Kinase ZC373.4.AA CAMK1 45-300 37 3.4e-90 262.37 In-house 1-276 (276) Show / Hide 
Range on Protein: 45-300
Range on HMM: 1-276/276
Sequence Identity: 37% (104 aa)

YQVTKLLGDGKFGKVYCVIEKET---GKEFAAKFIK---IRKEADR---AEVEREVSILT---QLRHPRIAQIYDAFYTTTNDVVLIMEIVRGGELFDRV
|...| .| | |..|| ...|||   ||..| | |.     |. |.   . .|.|..|..   .. || | ..|. .| ..|.. |.|| | |||||||.
YEFGKEIGRGAFSEVYLCTHKETQTNGKQYAIKCIDKKKFMKKKDMQKQEALENEIEIMKKVSKIDHPNIIKFYE-WYESDNHFYLVMELVTGGELFDRI

AEESYVLSELAVVMIICQLCEAIDYIHKQNILHLDVKPENIMCVSL-TGNRIK--LIDFGLARHYDGTQ-ELKYMAGTPEFAAPEVIKF---EKLDYHTD
 |   . .|   . |. |...|. |.|...| | | ||||. ...   .  ||  ..||||.. .|.    .| . |||.. ||||..    .  |.  |
VEKG-NYTEKDARHIMKQILSAVEYMHSKGIVHRDLKPENLLYYDKDEDSKIKRSIADFGLSKIFDHDENLMKTACGTPGYVAPEVLECKKDKPYDKACD

MWSIGVITYILLSGYSPFLGDN-LGETYCNVEKGVWEFTEE-FDTVTEE-AKDFVTKLLVYDQSKRMLPHECLQHPWI
|||||||||||| ||.|| ..|   | .  . |. .|| .  .| . .. ||||....|. | .||    .||.||||
MWSIGVITYILLCGYPPFYDENVDNELFEKIKKCEYEFPSPWWDNISDQEAKDFIKHMLEVDPKKRYTCEQCLNHPWI
Kinase ZC373.4.AA DRAK 47-300 36 7.7e-86 266.67 In-house 1-259 (259) Show / Hide 
Range on Protein: 47-300
Range on HMM: 1-259/259
Sequence Identity: 36% (95 aa)

VTKLLGDGKFGKVYCVIEKETGKEFAAKFIKIRKEAD--RAEVEREVSILTQLRHPRIAQIYDAFYTTTNDVVLIMEIVRGGELFD-RVAEESYVLSELA
  | .| |||  |   |.|.||..|||||.| |. .   |.|. .|. .|   .         . | |. ...|..|   |||.|.  ||..   ..|  
TAKERGRGKFAVVRKCIHKNTGQHFAAKFMKKRRRGQDCRMEILHEIAVLMLCQDCPWVINLHEVYETRSEMILVLEYAAGGEIFQYCVADKEECFCEKD

VVMIICQLCEAIDYIHKQNILHLDVKPENIMCVSLTGNR-IKLIDFGLARHYDGTQELKYMAGTPEFAAPEVIKFEKLDYHTDMWSIGVITYILLSGYSP
|. .. |  |.. | |..|| ||| || ||.  | .    ||..|||..|      |.  ..|||.. |||. ... .   ||||||||.||..|.. ||
VQRCMRQILEGVHYLHQRNIVHLDLKPQNILLTSEYPEDDIKICDFGMSRYICNGEEVREIMGTPDYVAPEILNYDPITMATDMWSIGVLTYVMLTHISP

FLGDNLGETYCNVEKGVWEFTEE-FDTVTEEAKDFVTKLLVYDQSKRMLPHECLQHPWI
|.||   ||. |.     .. || |. . ..| ||. .|.| .  .||   |||.|||.
FVGDDKQETFLNISQCNLDYSEEMFSCHSPVAIDFIQSLCVIKPEDRMTAEECLDHPWL
Kinase ZC373.4.AA CDPK 45-300 38 4.9e-82 251.43 In-house 1-271 (271) Show / Hide 
Range on Protein: 45-300
Range on HMM: 1-271/271
Sequence Identity: 38% (105 aa)

YQVTKLLGDGKFGKVYCVIEK-ETGKEF-AAKFIKIRKEADRAE---VEREVSILTQLRHPRIAQIYDAFYTTTNDVVLIME--IVRGGELFDRVAEESY
|.  | || | || |. |..|  |. |  | | |. ..  |  .   . .|. || || || | .||  ||   . . ..||  .. ||||||...|...
YKIKKVLGKGHFGQVRKVKHKQKTNQERVAMKIIPKSRVKDKEQQQQFFNEIEILKQLDHPNIIKIYE-FYQDEKNYYIVMETEYCTGGELFDYIIEKGH

VLSELAVVMIICQLCEAIDYIHKQNILHLDVKPENIMCVSLTGN-----RIKLIDFGLARHYDGT-----QELKYMAGTPEFAAPEVIKFEKLDYHTDMW
 ..|     |. |.  |. |.|..|| | |.|||||.  |   .      ||.||.|... .|.      . .. ..|||   ||||..    ..  | |
-FTEKEAAYIMRQILSAVNYCHSNNIVHRDLKPENILFDSKKDDSWVIYNIKVIDWGTSKKFDQNQKIEDKKMSQRCGTPYYIAPEVLQKK-YNEKCDIW

SIGVITYILLSGYSPFLGDNLGETYCNVEKGVWEFT-EEFDTVTEEAKDFVTKLLVYDQSKRMLPHECLQHPWI
|.||| ||||.|| || |.|  |.. .|.||. .|  .|.| ...|||| . |.|.||. |||   ..|||||.
SCGVILYILLCGYPPFYGKNDQEIMEKVKKGKYSFEGPEWDHISDEAKDLIRKMLCYDPKKRMSAQQALQHPWF
Kinase ZC373.4.AA Pkinase 45-300 30 3.5e-81 280.8 Pfam 1-293 (293) Show / Hide 
Range on Protein: 45-300
Range on HMM: 1-293/293
Sequence Identity: 30% (90 aa)

YQVTKLLGDGKFGKVYCVIEKETGKEFAAKFIKIRKEADRAEVE----REVSILTQLRHPRIAQIYDAFYTTTNDVVLIMEIVRGG----ELFDRVA-EE
|.. . .| | ||.||  ..| |||..| | || |.| .  ...    .|..|.  |.|| | ..||.|..  ... ..|| ..||    .|||..  ..
YHIGRKIGSGSFGCVYKCHHKGTGKIVAVKIIKKRHEKSWKDQTHRRLSEIQIMKRLNHPNIVRLYDWFED-KDHIYMVMEYCEGGLYVMDLFDYISTWR

SYVL--SELAVVMIICQLCEAIDYIHKQNILHLDVKPENIMCVSLTGNR---IKLIDFGLARH--YDGTQELKYMAGTPEFAAPEVIK-FEKLDYHTDMW
. ..  ||  . ... |......|.|...|.| |.|||||...  .|.    .|..|||||..  |   . ..  .|||...|||||.  .. ..  |||
HGCFYFSEWECKFYMYQILRGLEYCHSMGIIHRDLKPENILID-NNGHIDACVKICDFGLAKQFDY-NNS-MTTFCGTPWYMAPEVIRGGQYYGPKVDMW

SIGVITYILLSGYSPFLGD------NLGETYCNVEKGVWEFTEEFD------------------TVTEEAKDFVTKLLVYDQSKRMLPHECLQHPWI
|.|.| |..|.|. || |.      .  . .|.. .. ..| .. .                   ..||.|||....| .| .||  ....|||||.
SCGCILYEMLCGRPPFPGHCWHDNHDQMQMICRIMGPPLHFDWPWWCSISYFFFRHWHFHWTFHNWSEECKDFIKWCLCKDPKKRPTAEQILQHPWF
Kinase ZC373.4.AA CAMK-Unique 45-300 26 2.1e-76 251.67 In-house 1-363 (363) Show / Hide 
Range on Protein: 45-300
Range on HMM: 1-363/363
Sequence Identity: 26% (95 aa)

YQVTKLLGDGKFGKVYCVIEKETGKEFAAKFIKI-RKEADRAEV-------------------EREVSILTQLRHPRIAQIYDA----FYTTTN------
|   ...|.| ||.|| .. .||||..| | .|  . . ..  .                   .||..|.  . ||.| ..||     | . ..      
YKMHRIIGHGNFGHVYECMDRETGKKWACKMVKKQTHGNKKQKQQRNFDLRYKITEKRRDMKLKREHQIWKMVDHPNIIKLYDWNNPIFCDRKYPLCDLI

--------DVVLIMEIVRGGELFDRVAEE-------------------SYVLSE--LAVVMIICQLCEAIDYIHKQNILHLDVKPENIM-CVSLT-----
        . ...||.. ||.||| ...                      ..||    .  |. .| .|. | |.|.| | | |.|||| | |.      
IKTPRALPYMYIVMEYCQGGDLFDWIQKWDEFYFNFIIKFDFNILKRCQGHFSERCWDTCFIMQCLLSAVAYMHSQDIVHRDLKLENIMVCYSFKDNNHH

--------GNRIKLIDFGLARHYDGTQELK---YMAGTPEFAAP--------------EVIKFEKLDYHT----DMWSIGVITYILLSGYSPFLGDNLG-
         ..|||.||||..||.. ..      | |||...||              |||.. . |..     | ||.|||.|..|.|..|| ...   
RDFPYDWSNWHIKLCDFGLCCHYNHNKMCHMMQTMCGTPCYMAPEIVFCKNYQEMTRDEVINMQCYDQQCSPASDIWSLGVIMYYMLCGCPPFDCECEDR

-------ETYCNVEKGVW-EFTEE-FDT---VTEEAKDFVTKLLVYDQSKRMLPHECLQHPWI
       |.. .  ||   .| .. ..    ...||||||......|...|    | |.|.||
DYENHDKEIFECICKGDYCNFDWKMWHGPDYISQEAKDFVKCCMTVDPDHRWSAKELLEHQWI
Kinase ZC373.4.AA Ciliate-E2 45-300 23 4.5e-74 252.4 In-house 1-365 (365) Show / Hide 
Range on Protein: 45-300
Range on HMM: 1-365/365
Sequence Identity: 23% (88 aa)

YQVTKLLGDGKFGKVYCVIEKETGKEFAAKF--------------------IKIRKEADRAEVEREVSILTQLR----------------HPRIAQIYDA
| . |..| | ||.|| .  ....|.|| |.                    .|| |. .  ....| .|. ...                || | ..|..
YKFIKKIGQGNFGSVYKCKVWKVQKQFAIKIIDQKQQRQQMQEKVKIKIYAMKIMKKNQIEQIKQEIHIMREINCFYKKINEKNILEQLNHPNIIKMYEC

FYT-TTNDVVLIMEIVRGGELFDRV-------------------AEESYVLSELAVV------MIICQLCEAIDYIHKQN-ILHLDVKPENIMCVSLTGN
|.. ..| . |.|| . ||.|||.                     | .|.  ... .      ..|.....|. |.|..| |.| | |||||.       
FQEKDDNNIYLVMEYCQGGDLFDYIKNNKKKRNHEIEKDKYFTEKEIKYIMKQILQGFKTKAEFYIACIILALEYLHSKNNIIHRDIKPENILF------

RIKLIDFGLARHYD----------GTQELKYMA-----------------------GTPEFAAPEVIKFEK---------LDYHTDMWSIGVITYILLSG
 ||.|||||.. ||          . .....                         |||.. |||... .|          ||  |.||.||| |..|.|
-IKIIDFGLSKKYDDDNQNRTHKQQCKWYMF-KNDTSRTPGYMDQIIQQNMFNTICGTPGYMAPEILNGKKYDNQQKQKGYDYKCDIWSLGVILYEMLFG

YSPFLGDNLGETYCNVEKGVWEFTEE---------------FDTVTEEAKDFVTK----LLVYDQSKRML-PHECLQHPWI
. ||        . . ... ..| ..               .. ...|.||.  |    .|..|..||.  . ..|.|||.
KPPF--------QQQIKQCKIDFPCPEWQKDTQCIQCKWKSWKKWSQECKDLIKKFGKRMLQKDPEKRITGWEQILNHPWF
Kinase ZC373.4.AA TyrKc 45-295 21 2e-11 -37.8 SMART 1-280 (280) Show / Hide 
Range on Protein: 45-295
Range on HMM: 1-280/280
Sequence Identity: 21% (64 aa)

YQVTKLLGDGKFGKVY-CVIEKETGKEFAAKFIKIRKEADRAEVEREVSILTQL--RHPRIAQIYDAFYTTT-------NDVVLIMEIVRGGELFDRVAE
 .  | || | ||.|| ..       . | | .|  .   |..  || .|...|  .|| | ..| .  |.          . ..|| . .| | |.  .
ITLGKKLGEGAFGEVYKGTWK----IQVAVKMLKEDA---REDFMREARIMCKLGGHHPNIVRLY-GVCTQQGRNFMYIEPLMIVMEYMPHGDLKDYLRK

ESYVLSELAVVMIICQLCEAIDYIHKQNILHLDVKPENIMCVSLTGNR-IKLIDFGLARHYDGT------QELKYMAG--TPEF------AAPEVIKFEK
    |.    . .  | ..  .|.|..|. | |    |..   .. |. .|  ||||.|  .        .. . ...     .       |||.|.. |
HRPKLCMKDLLSFCWQIACGMEYLHSKNCIHRDLAARNCL---VGENHTVKISDFGLSRDIYDDDQQGESKDYYRKKEHKGGKTMLPIRWMAPECINYGK

LDYHTDMWSIGVITY-ILLSGYSPFLG-----DNLGETYCNVEKGVWEFTEEFDT--------VTEEAKDFVTKLLVYDQSKR----MLPHECL
    .| || ||  . |.  | .|  |      .  | . .|..|  .  .  .          ..|  .  ..   .| ..|     . |||.
FTTKSDVWSFGVCMWEIFTYGQQPYPGMIQQMMSNQEVIEYVKQG--YRMPQPPNDYPMSFVCCPDEMYQIMKQCWHEDPEDRPTFSEI-HECF
Kinase ZC373.4.AA Pkinase_Tyr 45-165 24 1.6e-05 19.32 Pfam 1-134 (270) Show / Hide 
Range on Protein: 45-165
Range on HMM: 1-134/270
Sequence Identity: 24% (33 aa)

YQVTKLLGDGKFGKVYCVIEK----ETGKEFAAKFIKIRKEAD---RAEVEREVSILTQL-RHPRIAQIYDAFYTTTND--VVLIMEIVRGGELFDRVAE
 .  | || | ||.||  . |    .|. . | | .|     .   |..  ||..|..|| .|| | . | . .       . ..|| . .| | |   .
ITFGKKLGEGAFGEVYKGTWKGDPDNTKIPVAVKMLKEGAMHEQNCREDFMREAKIMKQLGHHPNIVRLYGVCTDQGEPNQIYIVMEYMPHGDLLDYLRK

E---SYVLSELAVVMIICQLCEAIDYIHKQNILH
       |.    . .  | ... .| . .|. |
HREDKQPLTMKDLLQMCWQIAKGMEYLESKNCIH