Gene ZK632.3 (Nematode worm)

ZK632.3

Species: Nematode worm
Alias: aSWK441, ZK632.3, CE00420
External Links: Wormbase Link ,
Annotation: WormBase Genetic Map location: III:1.08, WormBase Physical Map location: III: 9800458-9797816

Classification

Group: Atypical
Family: RIO
Subfamily: RIO3

Sequence

Name Sequence Type Origin Length Description Download
ZK632.3.AA Protein Genbank 510 None Fasta, JSON

Protein domain

Protein domains of ZK632.3.AA. The domains are annotated by HMM profiles from Pfam and SMART, as well as in-house data which includes HMMs of each individual kinase group, family and subfamily. Here is domain list in details, including sequence identity, significance and alignment. In particular, you can find can find the best hit kinase group/family/subfamily, which is helpful to understand the relationship between kinases.Kinase domain and best hit kinase group/family/subfamily are highlighted in red and blue. Visualized by pviz.

Usage: Zoom in selected region by dragging mouse and zoom out by double-clicking.

Show/hide domain list
Domain Protein name Domain Name Range Identity (%) Significance Score Profile Source Profile Range (length) Alignment
RIO ZK632.3.AA RIO 218-453 44 3.7e-139 469.51 SMART 1-253 (253) Show / Hide 
Range on Protein: 218-453
Range on HMM: 1-253/253
Sequence Identity: 44% (113 aa)

DKEEKATMDTSVDSDTRLLLLKWINQGVFDSVD--GIIATGKESAVLHA----AQDSATSYAIKVYKTTLSEFKNRSEYVKDDFRFK------NPRGVLK
|||..||.....|..||..|.|..|.|......  |.|.||||..| ||    .... ...|.|.|.|...|||....|...|||||      |.| . .
DKEDYATYEEVFDPRTRMTLYKMVNRGYIEEINNHGCISTGKEANVYHAMGGDFDKNGNECAVKIYRTSTTEFKRMWRYIQGDFRFKHGYHHINWRKMVR

IWAEREFMNLSRMAKHGLPCPQPVKVRRNVLVMSFLGDQGLAAPRLKNVEWEFFTDDERRNVYDQVQSIMCRMYKECLLVHADLSEFNLLLT-----PDN
.|||.||.||.||...|.|||.|...||.||||.|.||.|..|||||.||||....|.....|.|... |..||.|| ||||||||.|.|..     .|.
LWAEKEFRNLQRMYEAGVPCPKPIAWRRHVLVMEFIGDDGWPAPRLKDVEWEEWEMDFKWEYYWQIMEYMRKMYHECHLVHADLSEYNMLYHDLEDENDC

KVHVIDVSQAMDLSHPRSLQFLTRDIQNIITFFTRIGTPNLPTYVQLFNLITD
||..||.||.....||..|.||.|||.|||.||.|.|......| ..|. ||.
KVWIIDWSQSVECDHPMWLEFLERDIWNIINFFRRKGVDCDDIYREIFERITG
Kinase ZK632.3.AA RIO1 260-447 42 7.89999999999e-112 349.21 Pfam 1-200 (200) Show / Hide 
Range on Protein: 260-447
Range on HMM: 1-200/200
Sequence Identity: 42% (84 aa)

AVLHAAQ-DSAT-SYAIKVYKTTLSEFKNRSEYVKDDFRFK------NPRGVLKIWAEREFMNLSRMAKHGLPCPQPVKVRRNVLVMSFLG-DQGLAAPR
.| ||..  . .  .|.|.|.|....||....|...||||.      |.| . ..|||.||.||.||...|.|||.|. ..|.||||.|.| ..|..|||
NVYHAYSMEDGKDECAVKIYRTGTTCFKKMKRYRDYDFRFRHRYHHHNWRYMVRMWAEKEFRNLKRMYEAGVPCPKPIDWNRHVLVMEFIGDKDGWPAPR

LKNVEWEF-FTDDERRNVYDQVQS-IMCRMYKECLLVHADLSEFNLLLTPDNKVHVIDVSQAMDLSHPRSLQFLTRDIQNIITFFTRIGTPN-LPTYVQL
||.||.|. ....| . .||..   .|.|||.|| |||.||||.|.|...|.|...||..||....||..|.|| ||..|||.||.|.| ..  ... ..
LKDVEMELELSEEEAEEIYDEIIREYMRRMYQECGLVHGDLSEYNILVHDDGKPWIIDWPQAVEHDHPHALEFLERDCRNIINFFRRKGVDERVMDFREI
Kinase ZK632.3.AA RIO 225-435 29 2.5e-72 246.63 In-house 1-232 (276) Show / Hide 
Range on Protein: 225-435
Range on HMM: 1-232/276
Sequence Identity: 29% (70 aa)

MDTSVDSDTRLLLLKWINQGVFDSVDGIIATGKESAVLHAAQDSAT-----------SYAIKVYKTTLSEFKNRSEYVKDDFRFK------NPRGVLKIW
.   .|  ||... | .| |.  || . | .|||| . |..  .             ..|||...|.. .||.|  |....|.||      |.|   ..|
YEQTNDPYTRMIMYKMVNRGMVESVGNCIGVGKESDIYHCSNENGEDEKEDSKVIPTECAIKIHRTGRTSFKDRKKYRDGEFYFKHRHCKHNWRYMHRLW

AEREFMNLSRMAKHGLPCPQPVKVRRNVLVMSFLGDQGLAAPRLKNVEWEFFTDDERRNVYDQVQSIMCRMYKECLLVHADLSEFNLLLTPDNK------
|| |. |..|. . | ||| |. ..|.||||.|..  . .||......      ...  ||.|.   | |.| .| |||.|..|||...  . .      
AEKEMRNMKRLYQSGFPCPEPIDYKRHVLVMEFINHDQMPAPKYPMCQIHEH--ENMKHVYHQCMCYMRRLYQHCRLVHCDFNEFNMMWHDGKHDENDCG

VHVIDVSQAMDLSHPRSLQFLTRDIQNIITFFTR
. .||..|    .|| .| .. ||. ..  || .
FYMIDFPQMVEHDHPHALWYFRRDCKCVNMFFMK
Kinase ZK632.3.AA RIO3 222-462 43 6.3e-67 224.59 In-house 1-254 (254) Show / Hide 
Range on Protein: 222-462
Range on HMM: 1-254/254
Sequence Identity: 43% (112 aa)

KATMDTSVDSDTRLLLLKWINQGVFDSVDGIIATGKESAVLHAA--------QDS---ATSYAIKVYKTTLSEFKNRSEYVKDDFRFK------NPRGVL
..| . .||  ||||. | .| |..... | ||||||| |.||         .||    |  ||||.|||| |||||  |.|||||||      ||| . 
HSTAEKAVDPKTRLLMYKMVNSGMLETITGCIATGKESVVFHAYGGSMEDEKEDSKVIPTICAIKVFKTTLNEFKNRDKYIKDDFRFKDRFSKLNPRKIH

KIWAEREFMNLSRMAKHGLPCPQPVKVRRNVLVMSFLGDQGLAAPRLKNVEWEFFTDDERRNVYDQVQSIMCRMYKECLLVHADLSEFNLLLTPDNKVHV
..|||.|  ||.|| . |.|||  | ... .|||||.| . . ||.||.|    .  .| .. | |   .| ..|.|| ||||||||.|.|     || .
RMWAEKEMHNLARMQRAGIPCPTVVLLKKHILVMSFIGHDQVPAPKLKEVK---LNSEEMKEAYYQTLHLMRQLYHECTLVHADLSEYNMLWH-AGKVWL

IDVSQAMDLSHPRSLQFLTRDIQNIITFFTRIGTPNLPTYVQLFNLITDLDMVEDHDL
|||||... .||  |.|| || .|.  || . |  .  .  .||| .. |..  | . 
IDVSQSVEPTHPHGLEFLFRDCRNVSQFFQKGGVKEALSERELFNAVSGLNITADNEA
Kinase ZK632.3.AA RIO1 229-437 42 1.1e-65 224.51 In-house 3-216 (225) Show / Hide 
Range on Protein: 229-437
Range on HMM: 3-216/225
Sequence Identity: 42% (93 aa)

VDSDTRLLLLKWINQGVFDSVDGIIATGKESAVLHAAQDSAT--SYAIKVYKTTLSEFKNRSEYVKDDFRF------KNPRGVLKIWAEREFMNLSRMAK
.|  ||..| | .  |.   ..| |.||||  | ||        .||||.|||    || |  ||   |||       |||   ||||| |. || |.  
IDPRTRMILFKMLTRGIITEINGCISTGKETNVYHASETNGKRAEYAIKIYKTSILVFKDREKYVDGEFRFRHGHCKHNPRKMIKIWAEKEMRNLKRIYQ

HGLPCPQPVKVRRNVLVMSFLGDQGLAAPRLKNVEWEFFTDDERRNVYDQVQSIMCRMYKECLLVHADLSEFNLLLTPDNKVHVIDVSQAMDLSHPRSLQ
   ||| |. |. |||.|.|.|  | ||||||..  ..   |..  .| |.   | |||  | ||||||||.|.|   . |. .|||||     || || 
SEIPCPEPIMVKSNVLMMEFIGKDGMAAPRLKDY--QYKERDQYFHYYHQMIQYMRRMYQDCRLVHADLSEYNMLYH-NDKLYMIDVSQSVEHDHPHSLE

FLTRDIQNIITFFTRIG
|| .|. |.  .| . .
FLRMDCKNVNMYFMKHN