Gene KIN2 (Bakers Yeast)

KIN2

Species: Bakers Yeast
Alias: KIN2
External Links: Saccharomyces Genome Database Link ,
Annotation:

Classification

Group: CAMK
Family: CAMKL
Subfamily: Kin1

Sequence

Name Sequence Type Origin Length Description Download
KIN2.kin_dom Protein Kinase Domain Sugen global kinase HMM prediction 279 Kinase domain by global Sugen HMM Fasta, JSON
KIN2.AA Protein Refseq_NP 1147 Serine/threonine protein kinase; Kin2p [Saccharomyces cerevisiae] Fasta, JSON

Protein domain

Protein domains of KIN2.AA. The domains are annotated by HMM profiles from Pfam and SMART, as well as in-house data which includes HMMs of each individual kinase group, family and subfamily. Here is domain list in details, including sequence identity, significance and alignment. In particular, you can find can find the best hit kinase group/family/subfamily, which is helpful to understand the relationship between kinases.Kinase domain and best hit kinase group/family/subfamily are highlighted in red and blue. Visualized by pviz.

Usage: Zoom in selected region by dragging mouse and zoom out by double-clicking.

Show/hide domain list
Domain Protein name Domain Name Range Identity (%) Significance Score Profile Source Profile Range (length) Alignment
Kinase KIN2.AA Kin1 99-377 93 1.8e-254 851.64 In-house 1-279 (279) Show / Hide 
Range on Protein: 99-377
Range on HMM: 1-279/279
Sequence Identity: 93% (260 aa)

WEFLETVGAGSMGKVKLVKHRQTKEICVIKIVNRASKAYLHKQHSLPSPKNESEILERQKRLEKEIARDKRTVREASLGQILYHPHICRLFEMCTMSNHF
|||.|||||||||||||||||.|.|||||||||||.||||||||.||.||||..||||||||||||||||||.|||||||||||||||||||||||||||
WEFVETVGAGSMGKVKLVKHRYTNEICVIKIVNRATKAYLHKQHMLPPPKNEQDILERQKRLEKEIARDKRTIREASLGQILYHPHICRLFEMCTMSNHF

YMLFEYVSGGQLLDYIIQHGSLKEHHARKFARGIASALQYLHANNIVHRDLKIENIMISSSGEIKIIDFGLSNIFDYRKQLHTFCGSLYFAAPELLKAQP
|||||||||||||||||||||..||||||||||||||||||||||||||||||||||||.|.||||||||||||.|||||||||||||||||||||||||
YMLFEYVSGGQLLDYIIQHGSIREHHARKFARGIASALQYLHANNIVHRDLKIENIMISDSSEIKIIDFGLSNIYDYRKQLHTFCGSLYFAAPELLKAQP

YTGPEVDIWSFGIVLYVLVCGKVPFDDENSSILHEKIKKGKVDYPSHLSIEVISLLTRMIVVDPLRRATLKNVVEHPWM
||||||||||||||||||||||||||||||||||||||.||||||.||||||||||||||||||.||||||.||||.||
YTGPEVDIWSFGIVLYVLVCGKVPFDDENSSILHEKIKQGKVDYPQHLSIEVISLLTRMIVVDPKRRATLKQVVEHHWM
Kinase KIN2.AA CAMKL 99-377 36 6.8e-133 426.51 In-house 1-297 (297) Show / Hide 
Range on Protein: 99-377
Range on HMM: 1-297/297
Sequence Identity: 36% (116 aa)

WEFLETVGAGSMGKVKLVKH-RQTKEICVIKIVN--RASKAYLHKQHSLPSPKNESEILERQKRLEKEIARDKRTVREASLGQILY---HPHICRLFEMC
.....| | || ||||| .| | |.|   |||..  ....    |.. ..           ||.     ... |  ||... . |    ||.|..|.|. 
YRIGKTLGKGSFGKVKLATHIRTTGEKVAIKIIDKKKIWNDPWMKKNKCG-----------QKH----ESDM-RIRREIQIMKMLNIGKHPNIIKLYEVI

TMSNH------FYMLFEYVSGGQ--LLDYIIQH----GSLKEHHARKFARGIASALQYLHANNIVHRDLKIENIMISSSG--EIKIIDFGLSNIFD-Y--
. ..|      .|.  ||.|||   |.|||..|    |...|| ||.. | | ||..|.| ..|||||.| |||.....|   |||||||.||... .  
ETPEHDIETKKIYLVMEYCSGGEMDLFDYIVKHGHRRGRMPEHEARRYFRQIVSAVNYCHSHGIVHRDIKPENILLDENGNNNIKIIDFGFSNMYRPCIF

--RKQLHTFCGSLYFAAPELLKA--QPYTGPEVDIWSFGIVLYVLVCGKVPFDDE--------NSSILHEKIKKGKVDYP--SHLSIEVISLLTRMIVVD
   . |.|||||. ..|||...   .|| ||.||||| |..||..|||..||||.        |   |..||..|   .|  .|.| ....|. .| .|.
GPGQKLKTFCGSPPYMAPEIFQGNNKPYDGPKVDIWSCGVILYAMVCGYLPFDDDTYNKQGKDNI-YLYWKIMCG-YYPPIWYHVS-DCRDLIRKMLQVN

PLRRATLKNVVEHPWM
| .|.|......||||
PEKRPTIHQIMNHPWM
Kinase KIN2.AA CAMK 104-377 25 1.3e-107 347.97 In-house 1-425 (425) Show / Hide 
Range on Protein: 104-377
Range on HMM: 1-425/425
Sequence Identity: 25% (111 aa)

TVGAGSMGKVKLVKHRQTK------------EICVIKIVNRASKAYLH----------------------KQHSLPSPKNESEILERQKRLEKEIARDKR
| | || |||||..|..|.            . . |||...      .                      ..... . ..| ||. . . ...       
TLGRGSFGKVKLCIHKNTTGKERVHHIYTNGQKVAIKIIDKKKLKDKQNQDYSNCYKIDKSKCKHRYCWRRPKDRKNVRREIEIMKKLQGIGN-------

TVREASLGQILYHPHICRLFEMCTMSNH-------------------FYMLF---EYVSGG----QLLDYIIQHGS---------------LKEHHARKF
         .| ||.|..|.|.   ...                   .|| .   ||.|||     |.|||..||.               ..|. ||..
---------KLDHPNIIKLYEVYEDPHYFKNTNDYETSKQVFTKDKHMYMVMEIMEYCSGGELFDDLFDYIVEHGCYGEEFDQFDIVERGRFTEREARRY

ARGIASALQYLHANNIVHRDLKIENIMISSS-----------------GEIKIIDFGLSNIFDY------------------------RKQLHTFCGSLY
 | |.||..|.| .|||||||| |||.....                 . |||||||..|.||                          . ..||||...
FRQICSAVHYCHSHNIVHRDLKPENILLDDNNDDSDPVEHDEIFDWNNNNIKIIDFGFANKFDPGENNFMCSDYKGGEMHNQWTTPTEGQKMKTFCGTPE

FAA-PELLKA-------------QPYTGPEVDIWSFGIVLYVLVCGKVPFDDE-------------NSSILHEKIKKGKVD-YPSHLSI-----------
..| ||.|.              .|| ||..|.|| |..||...||. ||...             | . |.|||.||| | .|...|.           
YMAAPEVLNGKGHCNMQNATDEEKPYYGPKCDMWSCGVILYIMLCGYPPFYGDCDNEICEDEWIGMNDYELFEKIMKGKYDFPPPYFSPISCNYGPEWWD

------------EVISLLTRMIVVDPLRRATLKNVVEHPWM
            |...|. .| .||| .|.|.. . .||||
DISDEFHHFVSQECKDLIRKMLQVDPEKRMTIEQCLNHPWM
Kinase KIN2.AA AMPK 153-377 44 1e-96 287.64 In-house 31-254 (254) Show / Hide 
Range on Protein: 153-377
Range on HMM: 31-254/254
Sequence Identity: 44% (100 aa)

ILERQKRLEKEIARDKRTVREASLGQILYHPHICRLFEMC-TMSNHFYMLFEYVSGGQLLDYIIQHGSLKEHHARKFARGIASALQYLHANNIVHRDLKI
||..||  ...   ..|. || .. ... |||| .|.|        ..|  |||||| | |||..|| |.|. |..|   | |.. |.| ..||||||| 
ILNKQKIKDQDM--VERIQREIHILKLFRHPHIIQLYEVIIETPTDIFMVMEYVSGGELFDYIVKHGRLQEREACRFFQQIISGVEYCHRHMIVHRDLKP

ENIMISSSGEIKIIDFGLSNIFDYRKQLHTFCGSLYFAAPELLKAQPYTGPEVDIWSFGIVLYVLVCGKVPFDDENSSILHEKIKKGKVDYPSHLSIEVI
||. .    .||| ||||||.    ..| | |||   ||||.   ..| |||||||| |..||...||. |||||| . |  |||.|..  |..|| |. 
ENLLLDHNKNIKIVDFGLSNMMKDGEFLKTACGSPCYAAPEMISGKLYCGPEVDIWSCGVILYAMLCGYLPFDDENTPTLYKKIKNGEYYIPKFLSPEAK

SLLTRMIVVDPLRRATLKNVVEHPWM
.|. .|  |||. |.| . ...||| 
DLIKHMLQVDPMKRITIHDIRNHPWF
Kinase KIN2.AA S_TKc 99-377 29 1.9e-96 327.67 SMART 1-231 (231) Show / Hide 
Range on Protein: 99-377
Range on HMM: 1-231/231
Sequence Identity: 29% (86 aa)

WEFLETVGAGSMGKVKLVKHRQTKEICVIKIVNRASKAYLHKQHSLPSPKNESEILERQKRLEKEIARDKRTVREASLGQILYHPHICRLFEMCTMSNHF
.|.|...| |..|||....|. |..|. |||..                                    ... || .. .   ||.|..|....   .|.
YEILRKIGKGAFGKVYKCRHKKTGRIVAIKIIK------------------------------------EHIRREIQILKK-HHPNIVKLYDVFQD-DHL

YMLFEYVSG--GQLLDYIIQHGS------LKEHHARKFARGIASALQYLHANNIVHRDLKIENIMISSSGEIKIIDFGLSNIFDYRKQLHTFCGSLYFAA
|| .||..|  | |.||| ..|.      . | |||.... |..||.|.| ..|.||||| |||....  .|||.||||. ..      .||||.... |
YMVMEYCDGDLGDLFDYIKKRGRHGLRFPFPE-HARFYMYQICCALEYCHSHGIIHRDLKPENILLDE--HIKICDFGLARQL------TTFCGTPWYMA

PELLKAQPYTGPEVDIWSFGIVLYVLVCGKVPFDDENSSILHEKIKKGKVDYPSHLSIEVISLLTRMIVVDPLRRATLKNVVE-------HPWM
||.|   .|.....|.||.|..|| ..||. ||.  .   . .||.          | |..... .. ..|| .| |   . .       |||.
PEVL---GYGKCKCDWWSCGCILYEMLCGYPPFP--QMQMMFKKIG----------SPEAKDFIRKCLQKDPEKRPTA-EALQDEWDIKCHPWF
Kinase KIN2.AA MARK 172-377 45 4.5e-93 304.57 In-house 48-262 (262) Show / Hide 
Range on Protein: 172-377
Range on HMM: 48-262/262
Sequence Identity: 45% (98 aa)

REASLGQILYHPHICRLFEMCT--MSNH-FYMLFEYVSGGQLLDYIIQH--GSLKEHHARKFARGIASALQYLHANNIVHRDLKIENIMISSSG--EIKI
||... . | ||.| .||..     ..| .|.  ||.||| |.|||..|  | |.|  ||.. | | ||..|.| .||||||.| |||.| . |   |||
REIEIMKKLDHPNIIKLFHVIEQDTEQHQIYLIMEYASGGELYDYIKAHPNGRLHEEEARRIFRQIVSAVNYCHSKNIVHRDIKPENILIDENGNHNIKI

IDFGLSNIFDYRKQLHTFCGSLYFAAPELLKAQPYTGPEVDIWSFGIVLYVLVCGKVPFDDEN--SSILHEKIKKGKVDYPSHLSIEVISLLTRMIVVDP
||||.|...   . | ||||.. ..|||... .||.||.||||| |.|||..|||..|||. .     |..|| .|| |.|.|.| |  .|. |...|.|
IDFGFSICIPPGQKLNTFCGTPPYMAPEIFLKKPYDGPKVDIWSLGVVLYFMVCGYFPFDGDTQDYKELYKKILRGKYDIPCHVSKECRNLIQRLLTVNP

LRRATLKNVVEHPWM
 .|.|......||||
EERPTIEEIMKHPWM
Kinase KIN2.AA Pkinase 99-377 26 9e-89 306.02 Pfam 1-293 (293) Show / Hide 
Range on Protein: 99-377
Range on HMM: 1-293/293
Sequence Identity: 26% (86 aa)

WEFLETVGAGSMGKVKLVKHRQTKEICVIKIVNRASKAYLHKQHS--LPSPKNESEILERQKRLEKEIARDKRTVREASLGQILYHPHICRLFEMCTMSN
.......|.||.|.|.. .|. | .| ..||... ..    .|.   |                           .|... . | ||.|.||..... ..
YHIGRKIGSGSFGCVYKCHHKGTGKIVAVKIIKKRHEKSWKDQTHRRL---------------------------SEIQIMKRLNHPNIVRLYDWFEDKD

HFYMLFEYVSGG----QLLDYII--QHGSL--KEHHARKFARGIASALQYLHANNIVHRDLKIENIMISSSGEI----KIIDFGLSNIF-DYRKQLHTFC
| || .||. ||     | |||   .||..   |........ |...|.|.|...|.||||| |||.|.. |.|    ||.||||.  |   .....|||
HIYMVMEYCEGGLYVMDLFDYISTWRHGCFYFSEWECKFYMYQILRGLEYCHSMGIIHRDLKPENILIDNNGHIDACVKICDFGLAKQFDY-NNSMTTFC

GSLYFAAPELLKAQPYTGPEVDIWSFGIVLYVLVCGKVPFDDE------NSSILHEKIKKGKVDYPSHLS---------------------IEVISLLTR
|.....|||... ..| ||.||.||.|..|| ..||. ||...      .   ....|.........  .                      | ......
GTPWYMAPEVIRGGQYYGPKVDMWSCGCILYEMLCGRPPFPGHCWHDNHDQMQMICRIMGPPLHFDWPWWCSISYFFFRHWHFHWTFHNWSEECKDFIKW

MIVVDPLRRATLKNVVEHPWM
.. .|| .| | . ...|||.
CLCKDPKKRPTAEQILQHPWF
Kinase KIN2.AA NuaK 180-377 44 3.9e-88 231.72 In-house 56-252 (252) Show / Hide 
Range on Protein: 180-377
Range on HMM: 56-252/252
Sequence Identity: 44% (88 aa)

LYHPHICRLFEMCTMSNHFYMLFEYVSGGQLLDYIIQHGSLKEHHARKFARGIASALQYLHANNIVHRDLKIENIMISSSGEIKIIDFGLSNIFDYRKQL
| ||||   .|    ..   .  || ||| | ||| . .|| |. ||.| | |.||. | | ..|.||||| |||.    ...|| ||||||...  | |
LNHPHIIHIYEVFENKDKIVIVMEYASGGELYDYISECKSLPEREARHFFRQIVSAVHYCHKHRICHRDLKLENILLDQNCNAKIADFGLSNYYHDQKFL

HTFCGSLYFAAPELLKAQPYTGPEVDIWSFGIVLYVLVCGKVPFDDENSSILHEKIKKGKVDYPSHLSIEVISLLTRMIVVDPLRRATLKNVVEHPWM
||||||  .| ||    |||.||||| || |..||..| |  ||| ..   |   |..|.   | . |     |   |  |.| ||||. .. .|.|.
HTFCGSPLYASPEIVNGQPYHGPEVDCWSLGVLLYTMVYGTMPFDGHDFKHLVKQISQGAYYEPCKPSDACM-LIRWMLMVNPRRRATIYDICHHWWV
Kinase KIN2.AA QIK 168-377 39 1.1e-79 271.06 In-house 43-272 (272) Show / Hide 
Range on Protein: 168-377
Range on HMM: 43-272/272
Sequence Identity: 39% (91 aa)

KRTVREASLGQILYHPHICRLFEMCTMSNHFYMLFEYVSGGQLLDYIIQHGS--------------------LKEHHARKFARGIASALQYLHANNIVHR
....||  .   |||||| .|..     .  |.. || |.| . ||...||                     ..|  ||.    |.|| .|.|  |||||
QKCYREVQIMKMLYHPHIIKLYQVMETDDMMYIVTEYCSNGEMFDYLCKHGRKGVKMVNSPDIGDQVLMGVPMAENEARRWFWQICSAVHYCHKRNIVHR

DLKIENIMISSSGEIKIIDFGLSNIFDYRKQLHTFCGSLYFAAPELLKAQPYTGPEVDIWSFGIVLYVLVCGKVPFDDENSSILHEKIKKGKVDYPSHLS
||| |||.. .  .|||.|||.|| |   . | |.|||  .||||... . |.||.||||| |.||||||||. ||| ..   | ...  ||.  |  .|
DLKAENILLDNNMNIKIADFGFSNWFKQGQLLMTWCGSPPYAAPEMFEGKEYDGPKVDIWSMGVVLYVLVCGALPFDGKTLQNLRQRVLSGKFRIPFFMS

IEVISLLTRMIVVDPLRRATLKNVVEHPWM
 .  .|  .| |||| .| | .....|.||
QDCEHLIRHMLVVDPEHRYTIMQICQHRWM
Kinase KIN2.AA Ciliate-E2 99-377 24 2.4e-73 249.97 In-house 1-365 (365) Show / Hide 
Range on Protein: 99-377
Range on HMM: 1-365/365
Sequence Identity: 24% (94 aa)

WEFLETVGAGSMGKVKLVKHRQTKE---ICVIKIVN---------RASKAYLHKQHSLPSPKNESEILERQKRLEKEIA--RDKRTVREASLGQILYHPH
 .|..  | |. |.|...|......   | .|.  .          ..| |  |. .    ||. |.... ... .||     |.   | .. ..| ||.
YKFIKKIGQGNFGSVYKCKVWKVQKQFAIKIID-QKQQRQQMQEKVKIKIYAMKIMK----KNQIEQIKQEIHIMREINCFY-KKI-NEKNILEQLNHPN

ICRLFEMCT--MSNHFYMLFEYVSGGQLLDYIIQH-----------GSLKEHHARKFARGIAS---------------ALQYLHANN-IVHRDLKIENIM
|....|       |..|. .||..|| |.|||...           ....| ..... . |..               ||.||| .| |.|||.| |||.
IIKMYECFQEKDDNNIYLVMEYCQGGDLFDYIKNNKKKRNHEIEKDKYFTEKEIKYIMKQILQGFKTKAEFYIACIILALEYLHSKNNIIHRDIKPENIL

ISSSGEIKIIDFGLS----------------NIFDYRK-----------------QLHTFCGSLYFAAPELLKAQPYTG--------PEVDIWSFGIVLY
.     |||||||||                ... . |                 . .|.||.... ||| |. ..|..         ..||||.|..||
F-----IKIIDFGLSKKYDDDNQNRTHKQQCKWYMF-KNDTSRTPGYMDQIIQQNMFNTICGTPGYMAPEILNGKKYDNQQKQKGYDYKCDIWSLGVILY

VLVCGKVPFDDENSSILHEKIKKGKVDYP------------------SHLSIEVISLLTR----MIVVDPLRRAT-LKNVVEHPWM
 ...|| ||         ..||..|.|.|                   ..| |.. |. .    |...||  | |  . . .|||.
EMLFGKPPF--------QQQIKQCKIDFPCPEWQKDTQCIQCKWKSWKKWSQECKDLIKKFGKRMLQKDPEKRITGWEQILNHPWF
Kinase KIN2.AA Ciliate-E2-Unclassified 99-377 23 1.9e-72 247.03 In-house 1-352 (352) Show / Hide 
Range on Protein: 99-377
Range on HMM: 1-352/352
Sequence Identity: 23% (85 aa)

WEFLETVGAGSMGKVKLVKHRQTKEICVIKIVN-RASKAYLHKQHSLPSPKNESEILERQK------RLEKEIARDKRTVREASLGQILYHPHICRLFEM
 ..... | |. |||....|...|.. ..|. .   ... . ....    .|| ......|         . |. .        . . ..||.| ..|..
YKIIKQIGQGGFGKVYKCQHKKQKQYYAMKYMKKIQIYKQKQIMNKD-EIMNEMKEMNNKKKYHQRKY--NKIMQQ--------ILLNHPHPFIVKMFYC

CTMSNHFYMLFEYVSGGQLLDYIIQHGS-----------------LKEHHAR-----KFARGIASALQYLHANN-IVHRDLKIENIMISSSG---EIKII
 .  ...|.  ||. || |..|| . ..                 . | .|.     .... | ..|.||| .| |.|||.| |||.....|   .||||
FQDKQNIYIVMEYCEGGDLWQYIKKRKKQKQKGNDLFHNMKQRKIFTEQQAKYKKAKFYFAQILQGLEYLHHKNNIIHRDIKPENILFDNNGKNYYIKII

DFGLSNIFDYRKQ----------------LHTFCGSLYFA----APELLKAQPYTGP---EVDIWSFGIVLYVLVCGKVPFDDENSSI------------
|||.|   ..  .                ..||||....     |||.|. | | ..   ..||||.|..|| .. |. ||.|.|. .            
DFGISKKYQQNNNCDTNQQQKMQIWKQQMMWTFCGTPNYMPQYTAPEVLQGQNYDHSKAYKCDIWSLGVILYEMLFGYYPFYDNNCEQHQQLITQWINNA

----LHEKIKKGKVDYPS--------HLSIEVISLLT----RMIVVDPLRRATLKNVVEHPWM
    |...||......|.        |.| |.. ...    .|....|  | |.. . .|||.
YRKQLYQNIKQKNIQFPKFPWQQIPKHWSPEAKDFINDLLQKMLKKNPNKRITFEQILNHPWF
Kinase KIN2.AA MELK 180-377 44 5.2e-69 234.93 In-house 54-254 (254) Show / Hide 
Range on Protein: 180-377
Range on HMM: 54-254/254
Sequence Identity: 44% (89 aa)

LYHPHICRLFEMCTMSNHFYMLFEYVSGGQLLDYIIQHGSLKEHHARKFARGIASALQYLHANNIVHRDLKIENIMISSSGEIKIIDFGLSNIFDYRKQL
| | |||.|. .    . ..|..|| .||...||||..  |.|. .|.| | | ||. |.|.    ||||| ||...    ..|.|||||      ||  
LRHQHICQLYHYIETEDKIFMVMEYCPGGEMFDYIIRQDRLEEEETRHFFRQIVSAIAYVHSQGYAHRDLKPENLLFDEDHHLKLIDFGLCAKTKGRKDY

H---TFCGSLYFAAPELLKAQPYTGPEVDIWSFGIVLYVLVCGKVPFDDENSSILHEKIKKGKVDYPSHLSIEVISLLTRMIVVDPLRRATLKNVVEHPW
|   | |||. .|||||.. . | | | |.|| ||.||||.|| .||||.| .|.  || .|. . | .|| | . || .|. ||| .|  .||...|||
HNLQTCCGSPAYAAPELIQGKQYIGSEADVWSMGILLYVLMCGFLPFDDDNMMIMYKKIMSGCYEEPKWLSPESKQLLRHMLQVDPKKRISMKNLLNHPW

M
.
V
Kinase KIN2.AA Pkinase_Tyr 180-338 29 2e-21 73.2 Pfam 60-232 (270) Show / Hide 
Range on Protein: 180-338
Range on HMM: 60-232/270
Sequence Identity: 29% (51 aa)

L-YHPHICRLFEMCT-MSNH--FYMLFEYVSGGQLLDYIIQH----GSLKEHHARKFARGIASALQYLHANNIVHRDLKIENIMISSSGEIKIIDFGLSN
| .||.| ||   ||  . .   |. .||. .| ||||  .|    ..|. ..  .... ||....||...|..||||   |....... .|| ||||. 
LGHHPNIVRLYGVCTDQGEPNQIYIVMEYMPHGDLLDYLRKHREDKQPLTMKDLLQMCWQIAKGMEYLESKNCIHRDLAARNCLVTENNVVKICDFGLAR

IF----DY-RKQLHTFCGSLYFAAPELLKAQPYTGPEVDIWSFGIVLYVLVC-GKVP-FDDENSSILHEKI-KKG
       | ||. ..        ||| ..   .|  . |.||||.... ..  |. | . .   . . |.| ..|
DIYNDDYYYRKRGGGK-LPIKWMAPECINYGKFT-TKSDVWSFGVLMWEIFTYGEQPTYPGMSNEEVYEYIYEDG
Kinase KIN2.AA TyrKc 99-375 21 4.1e-16 37.78 SMART 1-280 (280) Show / Hide 
Range on Protein: 99-375
Range on HMM: 1-280/280
Sequence Identity: 21% (67 aa)

WEFLETVGAGSMGKVKLVKHRQTKEICVIKIVNRASKAYLHKQHSLPSPKNESEILERQKRLEKEIARDKRTVREASLGQIL--YHPHICRLFEMCTMS-
 ..... | |  |.| . . .   . . .| ..  .                                 .   |||..   |   ||.| ||.  || . 
ITLGKKLGEGAFGEVYKGTWK---IQVAVKMLKEDA--------------------------------REDFMREARIMCKLGGHHPNIVRLYGVCTQQG

------NHFYMLFEYVSGGQLLDYIIQHGS-LKEHHARKFARGIASALQYLHANNIVHRDLKIENIMISSSGEIKIIDFGLS-NIFDY-----RKQLHTF
         ....||...| |.||.  |.  |.  .  .|.  ||.  .||| .|..||||   |..... . .|| ||||| .| |.     .|.  . 
RNFMYIEPLMIVMEYMPHGDLKDYLRKHRPKLCMKDLLSFCWQIACGMEYLHSKNCIHRDLAARNCLVGENHTVKISDFGLSRDIYDDDQQGESKDYYRK

----CGS----LYFAAPELLKAQPYTGPEVDIWSFGIVLY-VLVCGKVPFDD-----ENSSILHEKIKKGKVDYPSHL---------SIEVISLLTRMIV
    .|     .   ||| ..   .| .. |.||||.... ..  |. |  .      . . ..|..|.|.   . .          . |. .. ..   
KEHKGGKTMLPIRWMAPECINYGKFT-TKSDVWSFGVCMWEIFTYGQQPYPGMIQQMMSNQEVIEYVKQGYRMPQPPNDYPMSFVCCPDEMYQIMKQCWH

VDPLRRATLKNVVEHP
 ||  | | ....|  
EDPEDRPTFSEIHECF
Kinase KIN2.AA AMPK 99-132 41 4.1e-09 23.28 In-house 1-34 (254) Show / Hide 
Range on Protein: 99-132
Range on HMM: 1-34/254
Sequence Identity: 41% (14 aa)

WEFLETVGAGSMGKVKLVKHRQTKEICVIKIVNR
    .| | |. ||||. .| .|.|   ||| |.
YIIGKTIGEGTFGKVKMGTHILTGEKVAIKILNK
Kinase KIN2.AA MARK 99-135 37 7e-06 15.44 In-house 1-37 (262) Show / Hide 
Range on Protein: 99-135
Range on HMM: 1-37/262
Sequence Identity: 37% (14 aa)

WEFLETVGAGSMGKVKLVKHRQTKEICVIKIVNRASK
 ..| | | || .||||. |. |..   |||... ..
YKMLKTIGHGSYAKVKLACHKHTGRKVAIKIYEKFKL
Kinase KIN2.AA MELK 99-132 35 1e-05 15.15 In-house 1-34 (254) Show / Hide 
Range on Protein: 99-132
Range on HMM: 1-34/254
Sequence Identity: 35% (12 aa)

WEFLETVGAGSMGKVKLVKHRQTKEICVIKIVNR
.|  ...|.| ..||||  |  | .   |||...
YEVHDEIGTGGFAKVKLACHILTNQMVAIKIMDK
Kinase KIN2.AA NuaK 99-130 40 1.5e-05 9.97 In-house 1-32 (252) Show / Hide 
Range on Protein: 99-130
Range on HMM: 1-32/252
Sequence Identity: 40% (13 aa)

WEFLETVGAGSMGKVKLVKHRQTKEICVIKIV
.||..| | |  |||||   ..|     || .
YEFQKTLGKGTYGKVKLATEHSTGREVAIKSI
Kinase KIN2.AA QIK 99-130 40 0.007997 7.27 In-house 1-32 (272) Show / Hide 
Range on Protein: 99-130
Range on HMM: 1-32/272
Sequence Identity: 40% (13 aa)

WEFLETVGAGSMGKVKLVKHRQTKEICVIKIV
 .   |.| |  . ||| .|| ||.   |||.
YDIERTIGKGNFAVVKLARHRITKTKVAIKII
KA1 KIN2.AA KA1 1101-1147 54 5e-25 87.11 Pfam 1-48 (48) Show / Hide 
Range on Protein: 1101-1147
Range on HMM: 1-48/48
Sequence Identity: 54% (26 aa)

ERPPIKFEIHIVKVR-IVGLAGVHFKKVSGNTWLYKELASYILKELNL
|....||||...||. ..||.||.||.||||.|.||.|.. ||||..|
EPEVVKFEIQVCKVPGRLGLYGVDFKRVSGNQWQYKDLCTKILKEMRL