KIN4

Species: Bakers Yeast
Alias: KIN4
External Links: Saccharomyces Genome Database Link ,
Annotation:

Classification

Group: CAMK
Family: CAMKL
Subfamily: Kin4

Sequence

Name Sequence Type Origin Length Description Download
KIN4.kin_dom Protein Kinase Domain Sugen global kinase HMM prediction 268 Kinase domain by global Sugen HMM Fasta, JSON
KIN4.AA Protein Refseq_NP 800 protein kinase; Kin4p [Saccharomyces cerevisiae] Fasta, JSON

Protein domain

Protein domains of KIN4.AA. The domains are annotated by HMM profiles from Pfam and SMART, as well as in-house data which includes HMMs of each individual kinase group, family and subfamily. Here is domain list in details, including sequence identity, significance and alignment. In particular, you can find can find the best hit kinase group/family/subfamily, which is helpful to understand the relationship between kinases.Kinase domain and best hit kinase group/family/subfamily are highlighted in red and blue. Visualized by pviz.

Usage: Zoom in selected region by dragging mouse and zoom out by double-clicking.

Domain Protein name Domain Name Range Identity (%) Significance Score Profile Source Profile Range (length) Alignment
Kinase KIN4.AA Kin4 46-313 89 2.6e-253 787.66 In-house 1-273 (273) Show / Hide
Range on Protein: 46-313
Range on HMM: 1-273/273
Sequence Identity: 89% (244 aa)

YIIGSTLGEGEFGKVKLGWTK--ASSSN---EVPKQVAIKLIRRDTIKKDADKEIKIYREINALKHLTHPNIIYLEEVLQNSKYIGIVLEFVSGGEFYKY
|||||||||||||||||||||  |.|||   ..|||||||||||||||.|.|||||||||||||||||||||||||||||||.|||||||.|.|||||||
YIIGSTLGEGEFGKVKLGWTKNFANSSNSTFDFPKQVAIKLIRRDTIKNDYDKEIKIYREINALKHLTHPNIIYLEEVLQNSRYIGIVLEYVCGGEFYKY

IQRKRRLKESSACRLFAQLISGVNYMHYKGLVHRDLKLENLLLDKHENLVITDFGFVNEFFEDNELMKTSCGSPCYAAPELVVSTKAYEARKADVWSCGV
|||||||||..||||||||||||.||||||||||||||||||||||||||||||||||||.|||||||||||||||||||||.|||.|||||||.|||||
IQRKRRLKEMNACRLFAQLISGVHYMHYKGLVHRDLKLENLLLDKHENLVITDFGFVNEFCEDNELMKTSCGSPCYAAPELVISTKPYEARKADIWSCGV

ILYAMLAGYLPWDDDHENPTGDDIARLYKYITQTPLKFPEYITPIPRDLLRRILVPNPRRRINLQTIKRHVWL
||||||||||||||||.||.||||||||.||.|||||||.||||||||||||.|||.||||||||.||||.||
ILYAMLAGYLPWDDDHNNPEGDDIARLYNYINQTPLKFPDYITPIPRDLLRRMLVPDPRRRINLQQIKRHEWL

Kinase KIN4.AA CAMKL 46-313 39 2.4e-130 418.22 In-house 1-297 (297) Show / Hide
Range on Protein: 46-313
Range on HMM: 1-297/297
Sequence Identity: 39% (121 aa)

YIIGSTLGEGEFGKVKLGWT-KASSSNEVPKQVAIKLIRRDTIKKDADKEIK-----------IYREINALKHLT---HPNIIYLEEVLQNSKY------
|.|| |||.| ||||||..  .        ..|||| | .. |..|  .. .           |.|||. .|.|    ||||| | ||......      
YRIGKTLGKGSFGKVKLATHIRTT-----GEKVAIKIIDKKKIWNDPWMKKNKCGQKHESDMRIRREIQIMKMLNIGKHPNIIKLYEVIETPEHDIETKK

IGIVLEFVSGGE--FYKYIQRK----RRLKESSACRLFAQLISGVNYMHYKGLVHRDLKLENLLLDKHE--NLVITDFGFVNEFFE----DNELMKTSCG
| .|.| .||||   . ||...    .|..|. |.|.| |..|.|||.| .| ||||.|.||.|||..   |. |.|||| |.. .    .....||.||
IYLVMEYCSGGEMDLFDYIVKHGHRRGRMPEHEARRYFRQIVSAVNYCHSHGIVHRDIKPENILLDENGNNNIKIIDFGFSNMYRPCIFGPGQKLKTFCG

SPCYAAPELVVS-TKAYEARKADVWSCGVILYAMLAGYLPWDDDHENPT--GDDIARLYKYITQTPLKFPEYITP-IPRDLLRRILVPNPRRRINLQTIK
||.|.|||.. .  | |...|.|.||||||||||. ||||.|||. | .   |.| .||. | ..  ..| .. .   |||.|..|..|| .|.... |.
SPPYMAPEIFQGNNKPYDGPKVDIWSCGVILYAMVCGYLPFDDDTYN-KQGKDNI-YLYWKIMCG-YYPPIWYHVSDCRDLIRKMLQVNPEKRPTIHQIM

RHVWL
.| |.
NHPWM

Kinase KIN4.AA AMPK 46-313 46 7.50000000001e-123 366.53 In-house 1-254 (254) Show / Hide
Range on Protein: 46-313
Range on HMM: 1-254/254
Sequence Identity: 46% (126 aa)

YIIGSTLGEGEFGKVKLGWTKASSSNEVPKQVAIKLIRRDTIKKDADKEIKIYREINALKHLTHPNIIYLEEVL-QNSKYIGIVLEFVSGGEFYKYIQRK
|||| |.||| |||||.|  .        ..|||| . .. ||.....| .| |||  || ..||.|| | ||.    . | .|.|.||||| . || ..
YIIGKTIGEGTFGKVKMGTHILT-----GEKVAIKILNKQKIKDQDMVE-RIQREIHILKLFRHPHIIQLYEVIIETPTDIFMVMEYVSGGELFDYIVKH

RRLKESSACRLFAQLISGVNYMHYKGLVHRDLKLENLLLDKHENLVITDFGFVNEFFEDNELMKTSCGSPCYAAPELVVSTKAYEARKADVWSCGVILYA
.||.|  |||.|.| |||| |.|  . ||||||.||||||.. |. | |||  |   .|.|. ||.|||||||||| ..| | |. .. |.|||||||||
GRLQEREACRFFQQIISGVEYCHRHMIVHRDLKPENLLLDHNKNIKIVDFGLSN-MMKDGEFLKTACGSPCYAAPE-MISGKLYCGPEVDIWSCGVILYA

MLAGYLPWDDDHENPTGDDIARLYKYITQTPLKFPEYITPIPRDLLRRILVPNPRRRINLQTIKRHVWL
|| |||| ||..       .. ||| |..   . |....|  .||....| ..|  ||. . |. | |.
MLCGYLPFDDEN-------TPTLYKKIKNGEYYIPKFLSPEAKDLIKHMLQVDPMKRITIHDIRNHPWF

Kinase KIN4.AA CAMK 51-313 25 4.3e-111 359.34 In-house 1-425 (425) Show / Hide
Range on Protein: 51-313
Range on HMM: 1-425/425
Sequence Identity: 25% (108 aa)

TLGEGEFGKVKLGWTKASS--------SNEVPKQVAIKLIRRDTIKKD------------------------ADKEIKIYREINALKH-------LTHPN
|||.| ||||||.  | .         ... ...|||| | .. .|..                        . .. ...|||. .|.       | |||
TLGRGSFGKVKLCIHKNTTGKERVHHIYTN-GQKVAIKIIDKKKLKDKQNQDYSNCYKIDKSKCKHRYCWRRPKDRKNVRREIEIMKKLQGIGNKLDHPN

IIYLEEVLQ------------NSKY--------IGIVL---EFVSGG----EFYKYIQRK---------------RRLKESSACRLFAQLISGVNYMHYK
|| | || .            . ..        . .|.   |..|||    . . ||...               .|..|. |.|.| |..|.|.|.| .
IIKLYEVYEDPHYFKNTNDYET-SKQVFTKDKHMYMVMEIMEYCSGGELFDDLFDYIVEHGCYGEEFDQFDIVERGRFTEREARRYFRQICSAVHYCHSH

GLVHRDLKLENLLLDKHE-----------------NLVITDFGFVNEFFE-----------------------DNELMKTSCGSPCYAA-PELVVS-T--
. ||||||.||.|||...                 |. |.|||| |.|..                       ....|||.||.|.|.| ||.. . .  
NIVHRDLKPENILLDDNNDDSDPVEHDEIFDWNNNNIKIIDFGFANKFDPGENNFMCSDYKGGEMHNQWTTPTEGQKMKTFCGTPEYMAAPEVLNGKGHC

---------KAYEARKADVWSCGVILYAMLAGYLPWDDDHENPT------GDDIARLYKYITQTPLKFPEYITPI------------------------P
         | |  .|.|.||||||||.|| ||.|...|..| .      |... .|.. |..    ||..  ..                         
NMQNATDEEKPYYGPKCDMWSCGVILYIMLCGYPPFYGDCDNEICEDEWIGMNDYELFEKIMKGKYDFPPPYFSPISCNYGPEWWDDISDEFHHFVSQEC

RDLLRRILVPNPRRRINLQTIKRHVWL
.||.|..|...| .|.... ...| |.
KDLIRKMLQVDPEKRMTIEQCLNHPWM

Kinase KIN4.AA S_TKc 46-313 30 1.9e-90 307.69 SMART 1-231 (231) Show / Hide
Range on Protein: 46-313
Range on HMM: 1-231/231
Sequence Identity: 30% (87 aa)

YIIGSTLGEGEFGKVKLGWTKASSSNEVPKQVAIKLIRRDTIKKDADKEIKIYREINALKHLTHPNIIYLEEVLQNSKYIGIVLEFVSG--GEFYKYIQR
| |. ..|.| ||||.... |        ..|||| |.           ..|.|||. ||.  ||||. | .| |. ... .|.|...|  |. ..||..
YEILRKIGKGAFGKVYKCRHKK-----TGRIVAIKIIK-----------EHIRREIQILKK-HHPNIVKLYDVFQD-DHLYMVMEYCDGDLGDLFDYIKK

KRR------LKESSACRLFAQLISGVNYMHYKGLVHRDLKLENLLLDKHENLVITDFGFVNEFFEDNELMKTSCGSPCYAAPELVVSTKAYEARKADVWS
..|      . |  |.....|......|.| .| .||||| ||.|||.  .. |.|||.  ..       .| ||.| | |||..     |  .|.|.||
RGRHGLRFPFPE-HARFYMYQICCALEYCHSHGIIHRDLKPENILLDE--HIKICDFGLARQL-------TTFCGTPWYMAPEVL----GYGKCKCDWWS

CGVILYAMLAGYLPWDDDHENPTGDDIARLYKYITQTPLKFPEYITPIPRDLLRRILVPNPRRRINLQTIKR-------HVWL
||.||| ||.|| |..         ......| |           .|  .|..|..|. .|..|.    . .       | |.
CGCILYEMLCGYPPFP---------QMQMMFKKIG----------SPEAKDFIRKCLQKDPEKRPTA-EALQDEWDIKCHPWF

Kinase KIN4.AA NuaK 46-313 39 1.3e-89 235.65 In-house 1-252 (252) Show / Hide
Range on Protein: 46-313
Range on HMM: 1-252/252
Sequence Identity: 39% (108 aa)

YIIGSTLGEGEFGKVKLGWTKASSSNEVPKQVAIKLIRRDTIKKDADKEIKIYREINALKHLTHPNIIYLEEVLQNSKYIGIVLEFVSGGEFYKYIQRKR
| .  |||.| .|||||.  . .      ..||||.|... |. ..|  ..| |||  .  | ||.||   ||  |.  | ||.|. |||| | || ...
YEFQKTLGKGTYGKVKLATEHSTG-----REVAIKSIKKCKIEDEQDM-VHIRREIEIMSSLNHPHIIHIYEVFENKDKIVIVMEYASGGELYDYISECK

RLKESSACRLFAQLISGVNYMHYKGLVHRDLKLENLLLDKHENLVITDFGFVNEFFEDNELMKTSCGSPCYAAPELVVSTKAYEARKADVWSCGVILYAM
.| |  | ..| | .| | | |  . .|||||||| |||.  |  | |||  | ...|.....| |||| || || .|  . |.    | || ||.||.|
SLPEREARHFFRQIVSAVHYCHKHRICHRDLKLENILLDQNCNAKIADFGLSN-YYHDQKFLHTFCGSPLYASPE-IVNGQPYHGPEVDCWSLGVLLYTM

LAGYLPWDDDHENPTGDDIARLYKYITQTPLKFPEYITPIP----RDLLRRILVPNPRRRINLQTIKRHVWL
  | .| |       |.|  .| | |.|      .|  | .    . | | .|  |||||  .  |  | |.
VYGTMPFD-------GHDFKHLVKQISQG-----AYYEPCKPSDACMLIRWMLMVNPRRRATIYDICHHWWV

Kinase KIN4.AA MARK 46-313 37 6.1e-88 287.53 In-house 1-262 (262) Show / Hide
Range on Protein: 46-313
Range on HMM: 1-262/262
Sequence Identity: 37% (104 aa)

YIIGSTLGEGEFGKVKLGWTKASSSNEVPKQVAIKLIRRDTIKKDA-DKEIKIYREINALKHLTHPNIIYLEEVLQ--NSKY-IGIVLEFVSGGEFYKYI
| .. |.|.| ..||||.  | .      ..|||| . .   |..   .  ...|||. .|.| ||||| | .| .  ...  | ...| .|||| | ||
YKMLKTIGHGSYAKVKLACHKHTG-----RKVAIKIYEKF--KLNDPQWMKNVMREIEIMKKLDHPNIIKLFHVIEQDTEQHQIYLIMEYASGGELYDYI

QRK--RRLKESSACRLFAQLISGVNYMHYKGLVHRDLKLENLLLDKHE--NLVITDFGFVNEFFEDNELMKTSCGSPCYAAPELVVSTKAYEARKADVWS
. .  .||.|. | |.| |..|.|||.| |. ||||.|.||.|.|..   |  |.|||| ... ... | .| ||.| |.|||. .. | |...|.|.||
KAHPNGRLHEEEARRIFRQIVSAVNYCHSKNIVHRDIKPENILIDENGNHNIKIIDFGFSICIPPGQKL-NTFCGTPPYMAPEI-FLKKPYDGPKVDIWS

CGVILYAMLAGYLPWDDDHENPTGDD--IARLYKYITQTPLKFPEYITPIPRDLLRRILVPNPRRRINLQTIKRHVWL
.||.||.|. ||.|.|       ||.  .  ||| |.    ..| .. .  |.|..|.|..|| .|. .. | .| |.
LGVVLYFMVCGYFPFD-------GDTQDYKELYKKILRGKYDIPCHVSKECRNLIQRLLTVNPEERPTIEEIMKHPWM

Kinase KIN4.AA Pkinase 46-313 29 9.6e-77 266.06 Pfam 1-293 (293) Show / Hide
Range on Protein: 46-313
Range on HMM: 1-293/293
Sequence Identity: 29% (88 aa)

YIIGSTLGEGEFGKVKLGWTKASSSNEVPKQVAIKLIRRDTIKKDADKEIKIYREINALKHLTHPNIIYLEEVLQNSKYIGIVLEFVSGG----EFYKYI
| ||...|.| ||.|...  | ..      .||.| |.....|.. |..    .||  .|.| ||||. | .. .....| .|.|.. ||    . . ||
YHIGRKIGSGSFGCVYKCHHKGTGK-----IVAVKIIKKRHEKSWKDQTHRRLSEIQIMKRLNHPNIVRLYDWFEDKDHIYMVMEYCEGGLYVMDLFDYI

Q--RKRRL--KESSACRLFAQLISGVNYMHYKGLVHRDLKLENLLLDKHENL----VITDFGFVNEF-FEDNELMKTSCGSPCYAAPELVVSTKAYEARK
.  |....   |  ... . |...|..|.| .| .|||||.||.|.|.. ..     |.|||.   |    |. |.| ||.| |.|||..  .  |  .|
STWRHGCFYFSEWECKFYMYQILRGLEYCHSMGIIHRDLKPENILIDNNGHIDACVKICDFGLAKQFDY-NNS-MTTFCGTPWYMAPEVIR-GGQYYGPK

ADVWSCGVILYAMLAGYLPWDDDHENPTGDDIARLYKYITQTPLKFPEYIT---------------------PIPRDLLRRILVPNPRRRINLQTIKRHV
.|.||||.||| || |..|....   .. .|   ... | ..||.|... .                     .  .|.....| ..| .|.. . |. | 
VDMWSCGCILYEMLCGRPPFPGHCWHDN-HDQMQMICRIMGPPLHFDWPWWCSISYFFFRHWHFHWTFHNWSEECKDFIKWCLCKDPKKRPTAEQILQHP

WL
|.
WF

Kinase KIN4.AA BRSK 46-313 40 9.6e-77 261.0 In-house 1-254 (254) Show / Hide
Range on Protein: 46-313
Range on HMM: 1-254/254
Sequence Identity: 40% (108 aa)

YIIGSTLGEGEFGKVKLGWTKASSSNEVPKQVAIKLIRRDTIKKDADKEIKIYREINALKHLTHPNIIYLEEVLQNSKYIGIVLEFVSGGEFYKYIQRKR
|... ||| |  |.||||  . .      | |||| | .           |. |||  .|   ||... . .|  |.||   .||.||||| . |  .| 
YRLEKTLGKGQTGLVKLGVHCVTG-----KKVAIKIINKEKLSNKESMLMKVEREIAIMKLIDHPHVMKMYDVYENKKYLYLILEHVSGGELFDYLVKKG

RLKESSACRLFAQLISGVNYMHYKGLVHRDLKLENLLLDKHENLVITDFGFVNEFFEDNELMKTSCGSPCYAAPELVVSTKAYEARKADVWSCGVILYAM
||.   | . | | ||.... | .   ||||| ||||||   |  | |||       .  .. |||||| || || |..   |  ||||||||||||||.
RLTPKEARKFFRQIISALDFCHSHNICHRDLKPENLLLDEKNNIKIADFGMAS-LQVKDMMLHTSCGSPHYACPE-VIRGEKYDGRKADVWSCGVILYAL

LAGYLPWDDDHENPTGDDIARLYKYITQTPLKFPEYITPIPRDLLRRILVPNPRRRINLQTIKRHVWL
| | || ||       | . .|   . .     | .| |   ||||  .  .| .|| |. |..| | 
LVGALPFDD-------DNLRQLLEKVKRGVFHMPHFIHPDCQDLLRGMIEVDPDKRISLKEIQKHPWY

Kinase KIN4.AA QIK 46-313 34 2.9e-72 246.41 In-house 1-272 (272) Show / Hide
Range on Protein: 46-313
Range on HMM: 1-272/272
Sequence Identity: 34% (100 aa)

YIIGSTLGEGEFGKVKLGWTKASSSNEVPKQVAIKLIRRDTIKKDADKEIKIYREINALKHLTHPNIIYLEEVLQNSKYIGIVLEFVSGGEFYKYIQRKR
| |. |.| | |. |||.  .   .     .|||| | .  .  |..  .|.|||.  .| | ||.|| | .|.   ... || |. |.|| . |.  . 
YDIERTIGKGNFAVVKLARHRITKT-----KVAIKIIDKSQL--DEENLQKCYREVQIMKMLYHPHIIKLYQVMETDDMMYIVTEYCSNGEMFDYLCKHG

R--------------------LKESSACRLFAQLISGVNYMHYKGLVHRDLKLENLLLDKHENLVITDFGFVNEFFEDNELMKTSCGSPCYAAPELVVST
|                    ..|. | | | |..|.| | | .. |||||| ||.|||.  |  | |||| | .|.  .|..| |||| ||||| .   
RKGVKMVNSPDIGDQVLMGVPMAENEARRWFWQICSAVHYCHKRNIVHRDLKAENILLDNNMNIKIADFGFSN-WFKQGQLLMTWCGSPPYAAPE-MFEG

KAYEARKADVWSCGVILYAMLAGYLPWDDDHENPTGDDIARLYKYITQTPLKFPEYITPIPRDLLRRILVPNPRRRINLQTIKRHVWL
| |.  |.|.|| ||.||.. .| || |       |. .  | . .     . | ..     .| |. || .| .|.. . |..| |.
KEYDGPKVDIWSMGVVLYVLVCGALPFD-------GKTLQNLRQRVLSGKFRIPFFMSQDCEHLIRHMLVVDPEHRYTIMQICQHRWM

Kinase KIN4.AA TSSK 46-313 34 1.2e-71 234.38 In-house 1-289 (289) Show / Hide
Range on Protein: 46-313
Range on HMM: 1-289/289
Sequence Identity: 34% (105 aa)

YIIGSTLGEGEFGKVKLGWTKASSSNEVPKQ---------------VAIKLIRRDTIKKD-ADKEIKIYREINALKH-LTHPNIIYLEEVLQNSK-YIGI
|. | ..|.| ..||..    | | ..  |.               |||| | |   ..|  .|.  . ||| ...  | ||||| . | ....   | .
YNVGKKIGHGSYAKVYC----AYSKKHKCKHNPRLRDDLRIKRHTHVAIKIIDRKKAPTDYLNKF--LPREIQIMRKTLKHPNIIQFYEMFETCQGKIYM

VLEFVSGGEFYKYIQRK------RRLKESSACRLFAQLISGVNYMHYKGLVHRDLKLENLLLDKHENLVITDFGFVNEFFEDNE-----LMKTSCGSPCY
|.|. ..|    ||||.      ..|.|. | ..| |..|.| |.| .. ||||||.||.|||||.|. .|||||.... .| .     | || |||  |
VMEYAEHGDLLEYIQRRTQERCCGALHEEQARKWFRQMVSAVKYCHSHNVVHRDLKCENILLDKHWNIKLTDFGFARYWPRDDPGRCCHLSKTFCGSYAY

AAPELVVSTKAYEARKADVWSCGVILYAMLAGYLPWDDDHENPTGDDIARLYKYITQTPLKFP----EYITPIPRDLLRRILVPNPRRRINLQTIKRHVW
|||| . . . |   ..||||.|||||.|. | .| |||       .| .. . .   ...||    . |..  .||.|..| |.|..|.... |..| |
AAPEILRG-IPYDPKWYDVWSMGVILYIMVCGCMPFDDDK-----SNIHKMLWQQQEHKVCFPKPHSCWISQECKDLIRHMLQPHPCNRPHINEICHHCW

L
.
M

Kinase KIN4.AA Ciliate-E2 46-313 23 2.4e-66 226.7 In-house 1-365 (365) Show / Hide
Range on Protein: 46-313
Range on HMM: 1-365/365
Sequence Identity: 23% (90 aa)

YIIGSTLGEGEFGKVKLG--WTK----ASSSNEVPK--------QVAIKLIRRDTIKKD----ADKEIKIYREIN----------ALKHLTHPNIIYLEE
|..   .|.| ||.|...  | .    |   ..  |        .|.||..   ..||.      .||.|.||||           |..| ||||| . |
YKFIKKIGQGNFGSVYKCKVWKVQKQFAIKIID-QKQQRQQMQEKVKIKIYAMKIMKKNQIEQIKQEIHIMREINCFYKKINEKNILEQLNHPNIIKMYE

VLQ--NSKYIGIVLEFVSGGEFYKYIQ---RKR--------RLKESSACRLFAQLIS---------------GVNYMHYKG-LVHRDLKLENLLLDKHEN
. |  . ..| .|.|...||. ..||.    ||        ...|  ......|...               ...|.| |.  .|||.|.||.|.     
CFQEKDDNNIYLVMEYCQGGDLFDYIKNNKKKRNHEIEKDKYFTEKEIKYIMKQILQGFKTKAEFYIACIILALEYLHSKNNIIHRDIKPENILF-----

LVITDFGF----------------VNEFFEDN----------------ELMKTSCGSPCYAAPELVVSTKAY-------EARKADVWSCGVILYAMLAGY
. |.|||.                 ... . .                .. .| ||.| | ||| . . | .          |.|.||.||||| || |.
IKIIDFGLSKKYDDDNQNRTHKQQCKWYMF-KNDTSRTPGYMDQIIQQNMFNTICGTPGYMAPEILNGKKYDNQQKQKGYDYKCDIWSLGVILYEMLFGK

LPWDDDHENPTGDDIARLYKYITQTPLKFP------------------EYITPIPRDLLRR----ILVPNPRRRIN-LQTIKRHVWL
.|.               .. | | ...||                  .....   ||...    .|. .|  ||.  . |. | |.
PPF---------------QQQIKQCKIDFPCPEWQKDTQCIQCKWKSWKKWSQECKDLIKKFGKRMLQKDPEKRITGWEQILNHPWF

Kinase KIN4.AA Pkinase_Tyr 46-195 28 3.9e-21 72.22 Pfam 1-156 (270) Show / Hide
Range on Protein: 46-195
Range on HMM: 1-156/270
Sequence Identity: 28% (45 aa)

YIIGSTLGEGEFGKVKLGWTKASSSNEVPKQVAIKLIRRDTIKKDADKEIKIYREINALKHL-THPNIIYLEEVLQ-NSKY--IGIVLEFVSGGEFYKYI
 ..| .||||.||.|..|  |  .  .   .||.| .. .. ...  .  .  ||.. .|.|  ||||. |  |    ..   | ||.|.. .|  ..| 
ITFGKKLGEGAFGEVYKGTWKG-DPDNTKIPVAVKMLKEGAMHEQN-CREDFMREAKIMKQLGHHPNIVRLYGVCTDQGEPNQIYIVMEYMPHGDLLDYL

QR----KRRLKESSACRLFAQLISGVNYMHYKGLVHRDLKLENLLLDKHENLVITDFG
..    |..|. .  .   .|  .| .| . |...||||   | |...     |.|||
RKHREDKQPLTMKDLLQMCWQIAKGMEYLESKNCIHRDLAARNCLVTENNVVKICDFG

Kinase KIN4.AA TyrKc 46-311 22 3.8e-15 22.28 SMART 1-280 (280) Show / Hide
Range on Protein: 46-311
Range on HMM: 1-280/280
Sequence Identity: 22% (67 aa)

YIIGSTLGEGEFGKVKLGWTKASSSNEVPKQVAIKLIRRDTIKKDADKEIKIYREINALKHL--THPNIIYLEEVLQNS-------KYIGIVLEFVSGGE
   | .||||.||.| .|  |         |||.| .. |.       .  ..||.. ...|   ||||. |  |   .       . . ||.|....| 
ITLGKKLGEGAFGEVYKGTWK--------IQVAVKMLKEDA-------REDFMREARIMCKLGGHHPNIVRLYGVCTQQGRNFMYIEPLMIVMEYMPHGD

FYKYIQRKRR-LKESSACRLFAQLISGVNYMHYKGLVHRDLKLENLLLDKHENLVITDFGFVNEFFED------NELMKTSC--GSP--C---YAAPELV
  .|....|. |. .  .    |  .| .| | |...||||   | |...     |.|||   .  .|       .  ...   |.         |||  
LKDYLRKHRPKLCMKDLLSFCWQIACGMEYLHSKNCIHRDLAARNCLVGENHTVKISDFGLSRDIYDDDQQGESKDYYRKKEHKGGKTMLPIRWMAPECI

VSTKAYEARKADVWSCGVILYAMLA-GYLPWDDDHENPTGDDIARLYKYITQT-PLKFPEY--------ITPIPRDLLRRILVPNPRRRINLQTIKRHV
   |  .  | |||| || .. ..  |  |. .. ..    . .....|. |   .. |..         ..   .. ..    .|  | . ..|..  
NYGKFTT--KSDVWSFGVCMWEIFTYGQQPYPGMIQQ--MMSNQEVIEYVKQGYRMPQPPNDYPMSFVCCPDEMYQIMKQCWHEDPEDRPTFSEIHECF