Gene PKC1 (Bakers Yeast)

PKC1

Species: Bakers Yeast
Alias: PKC1
External Links: Saccharomyces Genome Database Link ,
Annotation:

Classification

Group: AGC
Family: PKC
Subfamily: PKC-Unclassified

Sequence

Name Sequence Type Origin Length Description Download
PKC1.kin_dom Protein Kinase Domain Sugen global kinase HMM prediction 260 Kinase domain by global Sugen HMM Fasta, JSON
PKC1.AA Protein Refseq_NP 1151 Protein Kinase C; Pkc1p [Saccharomyces cerevisiae] Fasta, JSON

Protein domain

Protein domains of PKC1.AA. The domains are annotated by HMM profiles from Pfam and SMART, as well as in-house data which includes HMMs of each individual kinase group, family and subfamily. Here is domain list in details, including sequence identity, significance and alignment. In particular, you can find can find the best hit kinase group/family/subfamily, which is helpful to understand the relationship between kinases.Kinase domain and best hit kinase group/family/subfamily are highlighted in red and blue. Visualized by pviz.

Usage: Zoom in selected region by dragging mouse and zoom out by double-clicking.

Show/hide domain list
Domain Protein name Domain Name Range Identity (%) Significance Score Profile Source Profile Range (length) Alignment
HR1 PKC1.AA HR1 5-72 30 7.1e-17 63.64 Pfam 1-74 (74) Show / Hide 
Range on Protein: 5-72
Range on HMM: 1-74/74
Sequence Identity: 30% (23 aa)

QLEQNIKKKIAVEENIIRGASALKK----KTSNVM---VIQKCNTNIREARQNLEYLEDSLKKLRLKTAQQSQGE
|  |...|||..| .|. || ....    .| | .   |.|.|....||..|..|||...|.||.. . . . ..
QRLQQLRKKIEREMKIKEGAENMRRAYQMTTDNKKHRKVRQQCQQMLRESNQKIEYLRMQLEKLQQRHQD-HPPN
HR1 PKC1.AA HR1 118-188 24 3.3e-15 57.67 Pfam 1-74 (74) Show / Hide 
Range on Protein: 118-188
Range on HMM: 1-74/74
Sequence Identity: 24% (18 aa)

YMLQQLEFKLQVEKQYQEANTKLTKLYQIDGDQRS----SSAAEGGAMESKYRIQMLNKALKKYQAINVDFDQFK
..||||..|...|... |.. .. ..||...| ..     .....   ||. .|. | ..|.|.|. ..| .   
QRLQQLRKKIEREMKIKEGAENMRRAYQMTTDNKKHRKVRQQCQQMLRESNQKIEYLRMQLEKLQQRHQD-HPPN
C2 PKC1.AA C2 210-305 17 1.8e-11 45.39 SMART 1-92 (92) Show / Hide 
Range on Protein: 210-305
Range on HMM: 1-92/92
Sequence Identity: 17% (21 aa)

VLTIGITAARDVDHIQSPMFARKPESYVTIKIDDTIKARTKPSR------NDRWSE---DFQIPVEKGNEIEITVYDKVNDSLIPVAIMWLL--------
.||. |  ||.               ||...       .||  .      | .| |    |...|   . ....|.|.      ..   ..         
TLTVHIIEARNLP-----------DPYVKVY-------KTKVVKNTLSGFNPVWNEWMETFYFDVHP-Q-LRFEVWDH-----DFIGHCCIPPNNPHWHQ

------LSDIAEEIRKKKA
      ||||  . |. . 
WDGCIHLSDIL-GYRH-WW
C2 PKC1.AA C2 211-288 19 2.9e-08 30.65 Pfam 1-90 (90) Show / Hide 
Range on Protein: 211-288
Range on HMM: 1-90/90
Sequence Identity: 19% (18 aa)

LTIGITAARDVDHIQSPMFARKPESYVTIKIDD----TIKARTKPSRND---RWSEDFQIP--VEKGNE-IEITVYDKVNDS---LIPVAI
|.. .  ||.    .. .. .|.  ||......    | | .||  .|.   .| |.|...  ...... ...||.|.  ..   .|  ..
LRVHVIEARNLPPMDW-DKNGKSDPYVKVYLGGDPKDTQKYKTKVIKNTLNPVWNETFTFDVPPPDLQHTLRFTVWDWDRFGRDDFIGQCC
C1_1 PKC1.AA C1_1 415-464 30 4.8e-17 66.22 Pfam 1-55 (55) Show / Hide 
Range on Protein: 415-464
Range on HMM: 1-55/55
Sequence Identity: 30% (17 aa)

HHFVQK-SFYNIMCCAYCGDFL----RYTGFQCQDCKFLCHKKCYTNVVTKCIAK
||.|.. .|.... |..||.|.    ...|..||.|...||..|...|...|. .
HHWVHHWNFKQPTFCCHCGEFCWGWLGHQGWKCQWCHYNCHHRCHMKVPPECGCN
C1 PKC1.AA C1 413-461 23 1e-11 46.2 SMART 1-61 (61) Show / Hide 
Range on Protein: 413-461
Range on HMM: 1-61/61
Sequence Identity: 23% (15 aa)

HGHHFVQKSFYNIMCCAYCGDFLRYT--------GFQCQDCKFLCHKKCYTNVVT-------KC
| .|.. .   . ..|..|.....          |..|..||. ||||| ..|          |
HHWHWWRF---KPTYCCHCRKMIWGMFKQHWKMQGYRCSWCKYKCHKKCHDKVPQQSHQDGWMC
C1_1 PKC1.AA C1_1 482-534 33 1.9e-14 56.67 Pfam 1-55 (55) Show / Hide 
Range on Protein: 482-534
Range on HMM: 1-55/55
Sequence Identity: 33% (19 aa)

HRFLPT-SNRGTKWCCHCGYILPWG--RHKVRKCSECGIMCHAQCAHLVPDFCGMS
|.. .. . .....||||| .. ||  .|   ||..|.  ||..|...||. ||..
HHWVHHWNFKQPTFCCHCGEFC-WGWLGHQGWKCQWCHYNCHHRCHMKVPPECGCN
C1 PKC1.AA C1 482-531 22 1.6e-07 32.24 SMART 1-61 (61) Show / Hide 
Range on Protein: 482-531
Range on HMM: 1-61/61
Sequence Identity: 22% (14 aa)

HRFLPTSNRGTKWCCHCGYILPWGRHK-----VRKCSECGIMCHAQCAHLVPD-------FC
|..  ..  . ..||||.  .  ....      ..||.|. .|| .|.. ||.        |
HHWHWWRF-KPTYCCHCRKMIWGMFKQHWKMQGYRCSWCKYKCHKKCHDKVPQQSHQDGWMC
Kinase PKC1.AA PKC 824-1083 57 1.2e-186 610.21 In-house 1-262 (262) Show / Hide 
Range on Protein: 824-1083
Range on HMM: 1-262/262
Sequence Identity: 57% (152 aa)

FVLLKVLGKGNFGKVILSKSKNTDRLCAIKVLKKDNIIQNHDIESARAEKKVFLLATKTKHPFLTNLYCSFQTENRIYFAMEFIGGGDLMWHVQNQ-RLS
| .|||||||.||||.|...|.||...||||||||.|||..|.|....||.|. ||.|  |||||.|.|.|||..|..|.||.. |||||.|.|.| |..
FNFLKVLGKGSFGKVMLAERKGTDEYYAIKVLKKDVIIQDDDVECTMTEKRVLALAWK--HPFLTHLHCCFQTMDRLFFVMEYVNGGDLMFHIQQQRRFK

VRRAKFYAAEVLLALKYFHDNGVIYRDLKLENILLTPEGHIKIADYGLCKDEMWYGNRTSTFCGTPEFMAPEILKEQEYTKAVDWWAFGVLLYQMLLCQS
...|.|||||...||...|..|.|||||||.|.||. ||||||||.|.||..||.|..||||||||...|||||..|||.|.|||||||||.|.|...||
EEHARFYAAEIICALQFLHEKGIIYRDLKLDNVLLDHEGHIKIADFGMCKENMWNGDTTSTFCGTPDYIAPEILQYQEYGKSVDWWAFGVLMYEMMAGQS

PFSGDDEDEVFNAILTDEPLYPIDMAGEIVQIFQGLLTKDPEKRLGAGPRD---ADEVMEEPFF
||.|.||||.|..|..|.|.||.... |.|.|..|..||.||||||..|..   .....|.|||
PFHGEDEDELFQSIMHDNPHYPRWLSKEAVSICKGFMTKNPEKRLGCHPQQEEGEQDIREHPFF
Kinase PKC1.AA AGC 824-1083 31 6.1e-166 433.07 In-house 1-395 (395) Show / Hide 
Range on Protein: 824-1083
Range on HMM: 1-395/395
Sequence Identity: 31% (127 aa)

FVLLKVLGKGNFGKVILSKSK------NTDRLCAIKVLKKDN-IIQNH--DIESARAE------------KKVFLLATKTK-------HPFLTN-LYCSF
| .|||.||| ||||.| . |       |....|.|||||.  |...   ..| . .|            .... .. .|.       |||... |..||
FEFLKVIGKGSFGKVYLVRKKDGCHKKDTGKYYAMKVLKKKHKIVIKKKNMVEHTMTEHWKQDQGYVWEERNILEKCNHTHNHPIKSHHPFIVKILHYSF

QTENR--IYFAME---------FIGGG-DLMWHVQNQ----RLSVRRAKFYAAE-------VLLALKYFHD-NGVIYRD-LKLENILLTPEGHIKIADYG
|....  .|| ||         ..||| .|..| |..    |..  ||.|||||       ..||| | |. .|.|.|| ||.|||||. .||||..| |
QDKDHTYLYFVMEYMPRYVNDLYCGGGCELFLHLQGRRKEGRFDEERARFYAAEMQKICGCIVLALEYLHSHMGIIHRDYLKPENILLDEDGHIKLTDFG

LCKDEMWYG--------------------------------------------------NRTSTFCG--TPEFMAPEILKEQEYTKAVDWWA--FGVLLY
|||  | .|                                                  .||.||||  |||.||||||    |.||.|||.  .|.|.|
LCKEGMNDGEKGQQSQSNMKFHWHNKKYQKSNMDTNKCNPNNWQRNNMSQEDDTTRKKRDRTWTFCGPCTPEYMAPEIL----YGKACDWWSFGLGCLMY

QMLLCQSPFSGD----------DEDEVFNAIL------TDEPLYP----------IDMAGEIVQIFQGLLTKDPEKRLGAGPRD-----ADEVMEEPFF
.||  ..||.||          ...|.|. |.      .... .|            .  | . . ..||.||||||||.|..|     |.|... |.|
EMLTGYPPFYGDNPQENRHPFRNPMEMFQKIMNGRYFINWKVKFPFPEDPQFPEDRWFSPEAKDLIKKLLCKDPEKRLGCGGNDFGDKGAEEIKNHPWF
Kinase PKC1.AA Alpha 824-1083 53 2e-123 416.33 In-house 1-259 (259) Show / Hide 
Range on Protein: 824-1083
Range on HMM: 1-259/259
Sequence Identity: 53% (140 aa)

FVLLKVLGKGNFGKVILSKSKNTDRLCAIKVLKKDNIIQNHDIESARAEKKVFLLATKTKHPFLTNLYCSFQTENRIYFAMEFIGGGDLMWHVQNQ-RLS
|  |.||||| ||||.|.  | || | |||.|||| |||  |.|    ||.|  |  |   |||. .   |||  | || ||.. |||||.|.|   .  
FNFLMVLGKGSFGKVMLAERKGTDELYAIKILKKDVIIQDDDVECTMVEKRVLALPGK--PPFLVQMHSCFQTMDRLYFVMEYVNGGDLMYHIQQVGKFK

VRRAKFYAAEVLLALKYFHDNGVIYRDLKLENILLTPEGHIKIADYGLCKDEMWYGNRTSTFCGTPEFMAPEILKEQEYTKAVDWWAFGVLLYQMLLCQS
   | |||||.  .| . |  |.||||||| |..|  ||||||||.|.|| .|| .. | ||||||...||||   | | |.||||||||||| |.  | 
EPHAVFYAAEIAIGLFFLHEKGIIYRDLKLDNVMLDAEGHIKIADFGMCKENMWEDQTTRTFCGTPDYIAPEIIAYQPYGKSVDWWAFGVLLYEMMAGQP

PFSGDDEDEVFNAILTDEPLYPIDMAGEIVQIFQGLLTKDPEKRLGAGPRDADEVMEEPFF
|| |.||||.| ||   .. ||  |  | |.| .|.||| | ||||.|| .  .. | |||
PFDGEDEDELFQAIMEHNVSYPKSMSKEAVDICKGFLTKHPNKRLGCGPDGEQDIREHPFF
Kinase PKC1.AA Eta 824-1083 52 4.3e-122 411.92 In-house 1-261 (261) Show / Hide 
Range on Protein: 824-1083
Range on HMM: 1-261/261
Sequence Identity: 52% (139 aa)

FVLLKVLGKGNFGKVILSKSKNTDRLCAIKVLKKDNIIQNHDIESARAEKKVFLLATKTKHPFLTNLYCSFQTENRIYFAMEFIGGGDLMWHVQNQR-LS
|  .|||||| ||||.| . |.|| . |||||||| |||  |.|   .||..  ||   ||||||.|.|.|||. |..| ||.. |||||...|  |   
FNFIKVLGKGSFGKVMLAERKGTDEVYAIKVLKKDVIIQDDDVECTMTEKRILSLA--RKHPFLTQLHCCFQTKDRLFFVMEYVNGGDLMFQIQRARKFD

VRRAKFYAAEVLLALKYFHDNGVIYRDLKLENILLTPEGHIKIADYGLCKDEMWYGNRTSTFCGTPEFMAPEILKEQEYTKAVDWWAFGVLLYQMLLCQS
  ||.|||||| .||.. |..|||||||||.||||  ||| |.||.|.||. .  |. |.||||||...|||||.|.||  .|||||.|||.| |.  |.
EPRARFYAAEVTCALMFLHQHGVIYRDLKLDNILLDHEGHCKLADFGMCKEGIMNGMTTTTFCGTPDYIAPEILQEMEYGPSVDWWAMGVLMYEMMCGQP

PFSGDDEDEVFNAILTDEPLYPIDMAGEIVQIFQGLLTKDPEKRLGAGP--RDADEVMEEPFF
||  | ||..|..|| |. |||. .  | | | .. .|| |.||||.     . ... . |||
PFEADNEDDLFESILHDDVLYPVWLHKEAVSILKAFMTKNPHKRLGCMTAQGGEHAIRQHPFF
Kinase PKC1.AA Delta 824-1083 48 1.2e-120 407.15 In-house 1-259 (259) Show / Hide 
Range on Protein: 824-1083
Range on HMM: 1-259/259
Sequence Identity: 48% (127 aa)

FVLLKVLGKGNFGKVILSKSKNTDRLCAIKVLKKDNIIQNHDIESARAEKKVFLLATKTKHPFLTNLYCSFQTENRIYFAMEFIGGGDLMWHVQN-QRLS
|...|||||| ||||.|.  |....  ||| |||| ...  |.|.   |..|  ||  ..||||. |.|.|||.. ..| ||.. |||||.|.|. .| .
FHFHKVLGKGSFGKVMLAELKGKNKYYAIKCLKKDVVLEDDDVECTMVERRVLALA--WEHPFLCHLFCTFQTKEHLFFVMEYLNGGDLMYHIQQCHRFD

VRRAKFYAAEVLLALKYFHDNGVIYRDLKLENILLTPEGHIKIADYGLCKDEMWYGNRTSTFCGTPEFMAPEILKEQEYTKAVDWWAFGVLLYQMLLCQS
 .||.|||.|....|.. | .|.|||||||.|.||  .|||||||.|.|| .|   ...|||||||...||||.| | |...||||.||||.| ||. ||
EKRARFYACEIICGLQFLHKKGIIYRDLKLDNVLLDCDGHIKIADFGMCKENMYGEKKASTFCGTPDYIAPEIIKGQKYNHSVDWWSFGVLMYEMLIGQS

PFSGDDEDEVFNAILTDEPLYPIDMAGEIVQIFQGLLTKDPEKRLGAGPRDADEVMEEPFF
||.|.||||.|..|. |.| ||  .  |  .....|. .|||||||     . .. . .||
PFHGEDEDELFWSICNDRPWYPRWITKEAKDCLKKLFERDPEKRLGVQYCPKGDIRQHCFF
Kinase PKC1.AA PKN 824-1083 53 9.90000000001e-120 404.07 In-house 1-260 (260) Show / Hide 
Range on Protein: 824-1083
Range on HMM: 1-260/260
Sequence Identity: 53% (138 aa)

FVLLKVLGKGNFGKVILSKSKNTDRLCAIKVLKKDNIIQNHDIESARAEKKVFLLATKTKHPFLTNLYCSFQTENRIYFAMEFIGGGDLMWHVQNQRLSV
| .. |||.| ||||.||. |.|... |||.||| .|.   ..||  .||..|  .....|||| ||.  ||||. ..| ||.  ||||| |. .   | 
FRCIAVLGRGHFGKVLLSQYKHTGEYYAIKALKKQDIVARDEVESLMCEKRIFEVVNRMRHPFLVNLFACFQTEEHVCFVMEYAMGGDLMMHIHEDVFSE

RRAKFYAAEVLLALKYFHDNGVIYRDLKLENILLTPEGHIKIADYGLCKDEMWYGNRTSTFCGTPEFMAPEILKEQEYTKAVDWWAFGVLLYQMLLCQSP
 || |||| | | |.| |.. .|||||||.|.||  ||..||||.||||. | || |||||||||||.|||.| .. ||.|||||  |||.| ||   .|
PRACFYAACVVLGLQYLHEHKIIYRDLKLDNLLLDTEGYVKIADFGLCKEGMGYGDRTSTFCGTPEFLAPEVLTDTSYTRAVDWWGLGVLIYEMLVGECP

FSGDDEDEVFNAILTDEPLYPIDMAGEIVQIFQGLLTKDPEKRLGAGPRDADEVMEEPFF
|.||||.|||..|. |.  ||  .. | ..| . || | ||.||||| |||...  .|||
FPGDDEEEVFDCIVNDDVRYPRFLSVEAIAIMRRLLRKNPERRLGAGERDAEDIKMQPFF
Kinase PKC1.AA Akt 824-1083 45 1.3e-115 371.1 In-house 1-264 (264) Show / Hide 
Range on Protein: 824-1083
Range on HMM: 1-264/264
Sequence Identity: 45% (121 aa)

FVLLKVLGKGNFGKVILSKSKNTDRLC-AIKVLKKDNIIQNHDIESARAEKKVFLLATKTKHPFLTNLYCSFQTENRIYFAMEFIGGGDLMWHVQ-NQRL
| .||||||| ||||.| | |.|...  |.|||||| |||.  .| . .|...     ...|||..||. ||||....|| |....||.| .| |  .| 
FDFLKVLGKGSFGKVFLVKKKDTQKWYYAMKVLKKDYIIQKNQVEHTKTERNIL---QHCNHPFIVNLHYSFQTQDKLYFVMDYCNGGELFYHLQRKRRF

SVRRAKFYAAEVLLALKYFHDNGVIYRD-LKLENILLTPEGHIKIADYGLCKDE-MWYGNRTSTFCGTPEFMAPEILKEQEYTKAVDWWA-FGVLLYQML
|  ||.||.||. ||. . | ...|||| ||.||||.  .|||...| ||||.. . .. .| ||||||| .|||||. . .|||||||. .|...| |.
SEDRARFYCAEIILAIEHLHSKNIIYRDYLKPENILMDKDGHICLTDFGLCKENIIKDHDKTKTFCGTPEYLAPEILNGNGHTKAVDWWGSLGCVMYEMM

LCQSPFSGDDEDEVFNAILTDEPLYP--IDMAGEIVQIFQGLLTKDPEKRLGAGPRDADEVMEEPFF
  . ||  .| .. |  |.. .  .|  .    |   .  |||.|||.||||.|| ||.|... |.|
CGRPPFYNQDHHQMFKKIKNQPVKFPDKDWISPECKDLISGLLNKDPKKRLGGGPNDAQEIKRHPWF
Kinase PKC1.AA SGK 824-1083 39 1.7e-98 304.82 In-house 1-283 (283) Show / Hide 
Range on Protein: 824-1083
Range on HMM: 1-283/283
Sequence Identity: 39% (113 aa)

FVLLKVLGKGNFGKVILSKSKNT------------------DRLCAIKVLKKDNII-------QNHDIESARAEKKVFLLATKTKHPFLTNLYCSFQTEN
| .|||.|||.|||| . | | .                  | . |.|||.|. ||       ..       ||..| |   . ||||. ||  .|||. 
FDFLKVIGKGSFGKVYQVKHKDDETCQRVWLIFQSLLSQSEDKFYAMKVLQKQHIINEYRQDLKKKEQKHIMAERNVIL--KNMKHPFIVNLHYAFQTKW

RIYFAMEFIGGGDLMWHVQ-NQRLSVRRAKFYAAEVLLALKYFHDNGVIYRDLKLENILLTPEGHIKIADYGLCKDEMWYGNRTSTFCGTPEFMAPEILK
  || |... ||..  | |  ....  ||.|||||. .|| | |.  .|||||| |||||  .||... | |||| ..   . |.||||||| .|||.|.
KLYFVMDYVNGGEMFYHLQREKHFPEDRARFYAAEIVCALEYLHSQDIIYRDLKPENILLDHQGHCCLTDFGLCKEGIKTNDTTFTFCGTPEYLAPEVLR

EQEYTKAVDWWAFGVLLYQMLLCQSPFSGDDEDEVFNAILTDEPLYPIDMAGEIVQIFQGLLTKDPEKRLGAGPRDADEVMEEPFF
 |.. ..||||  | .|| |.    ||   .  . .  |.  .   |  |  .   . ||||.|||.||||.  ||. |. . |||
KQPHDRTVDWWCLGCVLYEMMYGLPPFYSRNKQQMYDNIINQPLQIPPQMSNDAWDLIQGLLQKDPKKRLGTK-RDFMEIKNHPFF
Kinase PKC1.AA AktR 824-1083 38 3.7e-95 322.44 In-house 1-268 (268) Show / Hide 
Range on Protein: 824-1083
Range on HMM: 1-268/268
Sequence Identity: 38% (103 aa)

FVLLKVLGKGNFGKVILSKSK-NTDRLCAIKVLKKDNIIQNHDIESARAEKKVFLLATKTKHPFLTNLYCSFQTENRIYFAMEFIGGGDLMWHVQ-NQRL
|...|.||||.||||.| . | ..... |.|..|| .||..  .. .. |...  .. . .|||. .|. .|||.. ..|.||.. ||.|  | . ....
FHVYKCLGKGAFGKVYLVQKKRDNQKQYAMKMIKKKKIIERNQMHHTITERNI--MEMCCNHPFIVKLHYCFQTKEKLFFIMEYCPGGELFQHLKKKKKF

SVRRAKFYAAEVLLALKYFHDN-GVIYRDLKLENILLTPEGHIKIADYGLCK-DEMW-YGNRTSTFCGTPEFMAPEILKE-QEYTKAVDWWAFGVLLYQM
|  .|.||.|..|||| |.|..  .|||||| |||||  .||.||.|.|| |   |  |  .. .|||||| ||||.... . ..|.|||||||...| |
SEEQARFYFAQILLALEYLHQHMNIIYRDLKPENILLDEDGHVKITDFGLSKLQFMMHYDEKAYSFCGTPEYMAPEMITKKKGHNKSVDWWAFGIFIYEM

LLCQSPFSGDDEDEVFNAILTDE---PLYPIDMAGEIVQIFQ-GLLTKDPEKRLGAGPRDADEVMEEPFF
.  . ||  ..  . |  |.. .   . ||..   .   . | .|| |.|.|||| .  ...|. . |.|
VTGCPPFYHKNQNQMFQKIKIKQQNKFPYPSYFSSQCKDLIQRKLLCKNPNKRLGYYCNGWEEIKSHPWF
Kinase PKC1.AA S_TKc 824-1083 34 1e-93 318.53 SMART 1-231 (231) Show / Hide 
Range on Protein: 824-1083
Range on HMM: 1-231/231
Sequence Identity: 34% (94 aa)

FVLLKVLGKGNFGKVILSKSKNTDRLCAIKVLKKDNIIQNHDIESARAEKKVFLLATKTKHPFLTNLYCSFQTENRIYFAMEFIGG--GDLMWHVQNQR-
. .|...||| |||| . . |.|.|..|||..|          |..| | ..       .||.. .|| .||. ...|. ||...|  |||... .... 
YEILRKIGKGAFGKVYKCRHKKTGRIVAIKIIK----------EHIRREIQILKK----HHPNIVKLYDVFQD-DHLYMVMEYCDGDLGDLFDYIKKRGR

------LSVRRAKFYAAEVLLALKYFHDNGVIYRDLKLENILLTPEGHIKIADYGLCKDEMWYGNRTSTFCGTPEFMAPEILKEQEYTK-AVDWWAFGVL
      ..  .|.||......||.| |..|.|.|||| |||||.   ||||.| ||..         .||||||..||||.|    |.| ..|||..|..
HGLRFPFPE-HARFYMYQICCALEYCHSHGIIHRDLKPENILLDE--HIKICDFGLARQL-------TTFCGTPWYMAPEVL---GYGKCKCDWWSCGCI

LYQMLLCQSPFSGDDEDEVFNAILTDEPLYPIDMAGEIVQIFQGLLTKDPEKRLGAGPRDADE--VMEEPFF
|| ||  . ||.  .....|. |.            |  .. ...|.||||||..|    .||  ..  |.|
LYEMLCGYPPFP--QMQMMFKKIG----------SPEAKDFIRKCLQKDPEKRPTA-EALQDEWDIKCHPWF
Kinase PKC1.AA Iota 824-1083 44 5.1e-92 306.77 In-house 1-271 (271) Show / Hide 
Range on Protein: 824-1083
Range on HMM: 1-271/271
Sequence Identity: 44% (122 aa)

FVLLKVLGKGNFGKVILSKSKNTDRLCAIKVLKKDNIIQNHDIESARAEKKVFLLATKTKHPFLTNLYCSFQTENRIYFAMEFIGGGDLMWHVQNQR-LS
| |..|.|.| . ||.. . |.|.|. |.||.||. . .  ||.    ||.||  |    ||||  |   |||| |..| .||. |||||.|.| || | 
FELIRVIGRGSYAKVLMVEHKKTRRIYAMKVIKKEMVNDDEDIDWVQTEKHVFEQA--SNHPFLVGLHSCFQTESRLFFVIEFVNGGDLMFHMQRQRKLP

VRRAKFYAAEVLLALKYFHDNGVIYRDLKLENILLTPEGHIKIADYGLCKDEMWYGNRTSTFCGTPEFMAPEILKEQEYTKAVDWWAFGVLLYQMLLCQS
   |.||.||. |||.. |. |.|||||||.|.||  |||||. |||.||...  |  |||||||| ..|||||. ..|  .||||| |||.. |.   |
EEHARFYSAEICLALNFLHERGIIYRDLKLDNVLLDHEGHIKLTDYGMCKEGIRPGDTTSTFCGTPNYIAPEILRGEDYGFSVDWWALGVLMFEMMAGRS

PFS--G-------DDEDEVFNAILTDEPLYPIDMAGEIVQIFQGLLTKDPEKRLGAGPRD---ADEVMEEPFF
||   |         || .|  ||  .   |  ..    .. .| | |||. |||  |       .. | |||
PFDIVGNMDNPDQNTEDYLFQVILEKQIRIPRSLSVRAAHVLKGFLNKDPKERLGCHPQTNEGFMDIKEHPFF
Kinase PKC1.AA Pkinase 824-1083 29 1.5e-76 265.46 Pfam 1-293 (293) Show / Hide 
Range on Protein: 824-1083
Range on HMM: 1-293/293
Sequence Identity: 29% (89 aa)

FVLLKVLGKGNFGKVILSKSKNTDRLCAIKVLKKDNIIQNHDIESAR-AEKKVFLLATKTKHPFLTNLYCSFQTENRIYFAMEFIGGG----DLMWHVQ-
.......|.|.||.| . . |.| .. |.|..||...  . |.. .| .| .. .   .  ||.   ||..|.....||. ||. .||    ||. ... 
YHIGRKIGSGSFGCVYKCHHKGTGKIVAVKIIKKRHEKSWKDQTHRRLSEIQIMKRL-N--HPNIVRLYDWFEDKDHIYMVMEYCEGGLYVMDLFDYIST

--NQRL--SVRRAKFYAAEVLLALKYFHDNGVIYRDLKLENILLTPEGHI----KIADYGLCKD--EMWYGNRTSTFCGTPEFMAPEILK-EQEYTKAVD
  . ..  | . .|||. ..| .|.| |..|.|.||||.||||.  .|||    ||.| ||.|   .  ..  ..||||||..||||...  |.|...||
WRHGCFYFSEWECKFYMYQILRGLEYCHSMGIIHRDLKPENILIDNNGHIDACVKICDFGLAKQFDY-NNS--MTTFCGTPWYMAPEVIRGGQYYGPKVD

WWAFGVLLYQMLLCQSPFSGD------DEDEVFNAILTDEPLYPID---------------------MAGEIVQIFQGLLTKDPEKRLGAGPRDADEVME
.|..|..||.||. . ||.|.      |...... |.  .. ....                     .  |  ..  ..|.|||.||..     |.....
MWSCGCILYEMLCGRPPFPGHCWHDNHDQMQMICRIMGPPLHFDWPWWCSISYFFFRHWHFHWTFHNWSEECKDFIKWCLCKDPKKRPT-----AEQILQ

EPFF
 |.|
HPWF
Kinase PKC1.AA S_TK_X 1084-1146 35 1.9e-25 91.75 SMART 1-79 (79) Show / Hide 
Range on Protein: 1084-1146
Range on HMM: 1-79/79
Sequence Identity: 35% (28 aa)

RNINFDDILN--LRVKPPYIPEIK----SPEDTSYFEQEFTSAPPTLTPLPSVLTTSQQEE----------FRGFSFMP
|.|..|...|   ...||..|.||    ||.|||.|..|||...|.||| ...|. |....          ||||... 
RGIDWDKLYNQQKEIEPPFKPKIKEVYASPTDTSNFDPEFTEETPMLTPDDPPLSNSMWQNEMETEIPPDPFRGFTYVF
Kinase PKC1.AA Pkinase_C 1103-1148 44 3.1e-17 63.89 Pfam 1-46 (46) Show / Hide 
Range on Protein: 1103-1148
Range on HMM: 1-46/46
Sequence Identity: 44% (21 aa)

EIKSPEDTSYFEQEFTSAPPTLT-PLPSVLTTSQQEEFRGFSFMPDD
..|||.|||.|. |||..||..| | .. .. ..||.||||.. ..|
QVKSPTDTSNFDPEFTDEPPMDTPPDWR-MSSGDQEPFRGFTYVNPD
Kinase PKC1.AA TyrKc 824-1067 22 1.4e-15 29.11 SMART 1-280 (280) Show / Hide 
Range on Protein: 824-1067
Range on HMM: 1-280/280
Sequence Identity: 22% (65 aa)

FVLLKVLGKGNFGKVILSKSKNTDRLCAIKVLKKDNIIQNHDIESARAEKKVFLLATKT--KHPFLTNLYCSFQTE-------NRIYFAMEFIGGGDLMW
 .|.|.|| |.||.| . . |   . .|.|.||.|       .|  . | ..    .|   .|| . .||    ..         ..  ||.  .|||  
ITLGKKLGEGAFGEVYKGTWK---IQVAVKMLKEDA------REDFMREARIM---CKLGGHHPNIVRLYGVCTQQGRNFMYIEPLMIVMEYMPHGDLKD

HVQNQR--LSVRRAKFYAAEVLLALKYFHDNGVIYRDLKLENILLTPEGHIKIADYGLCKDEMWY---GNRTSTFCG----TPEF------MAPEILKEQ
. .. |  |...    ..  .     | |....| |||   |.|.. ....||.| ||..|   .   | ....          .      |||| ... 
YLRKHRPKLCMKDLLSFCWQIACGMEYLHSKNCIHRDLAARNCLVGENHTVKISDFGLSRDIYDDDQQGESKDYYRKKEHKGGKTMLPIRWMAPECINYG

EYTKAVDWWAFGVLLYQML-LCQSPFSG-----DDEDEVFNAILTDEPLYPIDM---------AGEIVQIFQGLLTKDPEKR---------L
..| . | |.|||... .. ..|.| .|      . .||.. . . . . . .            |. || .     |||.|         .
KFTTKSDVWSFGVCMWEIFTYGQQPYPGMIQQMMSNQEVIEYVKQGYRMPQPPNDYPMSFVCCPDEMYQIMKQCWHEDPEDRPTFSEIHECF
Kinase PKC1.AA Pkinase_Tyr 824-858 35 5e-06 20.92 Pfam 1-39 (270) Show / Hide 
Range on Protein: 824-858
Range on HMM: 1-39/270
Sequence Identity: 35% (14 aa)

FVLLKVLGKGNFGKVILSKSK----NTDRLCAIKVLKKD
 ...|.||.|.||.| . . |    ||.  .|.|.|| .
ITFGKKLGEGAFGEVYKGTWKGDPDNTKIPVAVKMLKEG
Kinase PKC1.AA Pkinase_Tyr 991-1015 44 0.000343 14.82 Pfam 181-205 (270) Show / Hide 
Range on Protein: 991-1015
Range on HMM: 181-205/270
Sequence Identity: 44% (11 aa)

MAPEILKEQEYTKAVDWWAFGVLLY
|||| ... ..| . | |.||||..
MAPECINYGKFTTKSDVWSFGVLMW
Kinase PKC1.AA Pkinase_Tyr 954-973 45 0.090957 6.61 Pfam 141-160 (270) Show / Hide 
Range on Protein: 954-973
Range on HMM: 141-160/270
Sequence Identity: 45% (9 aa)

NILLTPEGHIKIADYGLCKD
|.|.| ....||.| ||..|
NCLVTENNVVKICDFGLARD