Gene PKH2 (Bakers Yeast)

PKH2

Species: Bakers Yeast
Alias: PKH2
External Links: Saccharomyces Genome Database Link ,
Annotation:

Classification

Group: AGC
Family: PDK1

Sequence

Name Sequence Type Origin Length Description Download
PKH2.kin_dom Protein Kinase Domain Sugen global kinase HMM prediction 265 Kinase domain by global Sugen HMM Fasta, JSON
PKH2.AA Protein Refseq_NP 1081 Pkb-activating Kinase Homologue; Pkh2p [Saccharomyces cerevisiae] Fasta, JSON

Protein domain

Protein domains of PKH2.AA. The domains are annotated by HMM profiles from Pfam and SMART, as well as in-house data which includes HMMs of each individual kinase group, family and subfamily. Here is domain list in details, including sequence identity, significance and alignment. In particular, you can find can find the best hit kinase group/family/subfamily, which is helpful to understand the relationship between kinases.Kinase domain and best hit kinase group/family/subfamily are highlighted in red and blue. Visualized by pviz.

Usage: Zoom in selected region by dragging mouse and zoom out by double-clicking.

Show/hide domain list
Domain Protein name Domain Name Range Identity (%) Significance Score Profile Source Profile Range (length) Alignment
Kinase PKH2.AA PDK1 179-443 52 7.4e-209 646.63 In-house 1-307 (307) Show / Hide 
Range on Protein: 179-443
Range on HMM: 1-307/307
Sequence Identity: 52% (162 aa)

FKFGSVIGDGAYSTVMLATSIDT----KKRYAAKVLNKEYLIRQKKVKYVSIEKTALQKLNNS----PSVVRLFSTFQDESSLYFLLEYAPNGDFLSLMK
|.||..||.|.||||.||....|    .|.|| |...|.|.||.||||||..||.....|||.    |..|.|. |||||..|||.|||.||||.|..||
FIFGKNIGEGSYSTVYLAREKETKNDENKMYAIKICEKRYIIREKKVKYVHREKEIMCHLNNECNGHPGIVKLYFTFQDEQCLYFVLEYCPNGDLLHYMK

K--YGSLDETCARYYAAQIIDAIDYLHSNGIIHRDIKPENILLDGEMKIKLTDFGTA---KLLNP---------------TNNSVSKPEYDLSTRSKSFV
|  .||.|..|.|.|||.||||...||||||||||.|||||||| .|.|..||||||   |.|..               .|....|||.|..||.||||
KQPFGSFDMDCCRFYAAEIIDALEHLHSNGIIHRDLKPENILLDKDMHIMITDFGTAGFDKILPEYQSQQQNQFQQQFQQHNKGMDKPEEDKQTRCKSFV

GTAEYVSPELLNDSFTDYRCDIWAFGCILFQMIAGKPPFKAT-----NEYLTFQKVMKVQYAFTPG--FPLIIRDLVKKILVKNLDRRLT-------ISQ
|||||||||||.|......|||||.|||..||.||.|||...     |||.||||.||.||.|...  || ...|||||.||.. ..|||       ..|
GTAEYVSPELLTDKECTPSCDIWALGCIIYQMVAGQPPFRGMNDATNNEYHTFQKIMKCQYDFPDNFRFPPCAKDLVKKLLVRDPNDRLTSCDECGGYQQ

IKEHHFF
||.|.||
IKAHPFF
Kinase PKH2.AA AGC 179-443 29 3e-146 380.99 In-house 1-395 (395) Show / Hide 
Range on Protein: 179-443
Range on HMM: 1-395/395
Sequence Identity: 29% (119 aa)

FKFGSVIGDGAYSTVMLATSI------DTKKRYAAKVLNKEY---LIRQKKVKYVSIE------------KTALQKLNN---------SPSVVR-LFSTF
|.|  ||| |....|.|.         ||.| || |||.|..   ......|... .|            .  |.|.|.         .| .|. |...|
FEFLKVIGKGSFGKVYLVRKKDGCHKKDTGKYYAMKVLKKKHKIVIKKKNMVEHTMTEHWKQDQGYVWEERNILEKCNHTHNHPIKSHHPFIVKILHYSF

QDESS--LYFLLEYAP---------NG-DFLSLMK---KYGSLDETCARYYAAQ-------IIDAIDYLHS-NGIIHRD-IKPENILLDGEMKIKLTDFG
||..   |||..||.|          | .... ..   |.|..|| .||.|||.       |. |..|||| .|||||| .|||||||| .  |||||||
QDKDHTYLYFVMEYMPRYVNDLYCGGGCELFLHLQGRRKEGRFDEERARFYAAEMQKICGCIVLALEYLHSHMGIIHRDYLKPENILLDEDGHIKLTDFG

TAKLLNP-------------------------------------TNNSVSKPEYDLSTRSK------SFVG--TAEYVSPELLNDSFTDYRCDIWA--FG
 .| ..                                       || .|. | |..|| |      .|.|  |.||..|| |     .. ||.|.  .|
LCKEGMNDGEKGQQSQSNMKFHWHNKKYQKSNMDTNKCNPNNWQRNN-MSQ-E-DDTTR-KKRDRTWTFCGPCTPEYMAPEIL----YGKACDWWSFGLG

CILFQMIAGKPPFKATN----------EYLTFQKVM--------KVQYAFT--------PGFPLIIRDLVKKILVKNLDRRLT----------ISQIKEH
|....|..|.||| . |          .. .|||.|        ||.. |         . |    .||.|| |.|. ..||.          ...||.|
CLMYEMLTGYPPFYGDNPQENRHPFRNPMEMFQKIMNGRYFINWKVKFPFPEDPQFPEDRWFSPEAKDLIKKLLCKDPEKRLGCGGNDFGDKGAEEIKNH

HFF
 .|
PWF
Kinase PKH2.AA S_TKc 179-443 30 1.3e-97 331.56 SMART 1-231 (231) Show / Hide 
Range on Protein: 179-443
Range on HMM: 1-231/231
Sequence Identity: 30% (86 aa)

FKFGSVIGDGAYSTVMLATSIDTKKRYAAKVLNKEYLIRQKKVKYVSIEKTALQKLNNSPSVVRLFSTFQDESSLYFLLEYAPN--GDFLSLMKKYGS--
.... .|| ||...|.... ..|....| |...          . .  |   |.|  . | .|.|. .||| ..||. .||...  || ....||.|.  
YEILRKIGKGAFGKVYKCRHKKTGRIVAIKIIK----------EHIRREIQILKK--HHPNIVKLYDVFQD-DHLYMVMEYCDGDLGDLFDYIKKRGRHG

----LDETCARYYAAQIIDAIDYLHSNGIIHRDIKPENILLDGEMKIKLTDFGTAKLLNPTNNSVSKPEYDLSTRSKSFVGTAEYVSPELLNDSFTDY-R
    ..|  ||.|..||..|..|.||.||||||.||||||||    ||..||| |..|                  ..|.|| .|..||.|     .. .
LRFPFPE-HARFYMYQICCALEYCHSHGIIHRDLKPENILLDE--HIKICDFGLARQL------------------TTFCGTPWYMAPEVL---GYGKCK

CDIWAFGCILFQMIAGKPPFKATNEYLTFQKVMKVQYAFTPGFPLIIRDLVKKILVKNLDRRLTISQIKE-------HHFF
||.|..||||. |..|.|||   .....|.|..          .   .|...|.|.|. ..|.|. .. .       | .|
CDWWSCGCILYEMLCGYPPFP--QMQMMFKKIG----------SPEAKDFIRKCLQKDPEKRPTA-EALQDEWDIKCHPWF
Kinase PKH2.AA CAMK 184-443 22 1.5e-88 285.42 In-house 1-425 (425) Show / Hide 
Range on Protein: 184-443
Range on HMM: 1-425/425
Sequence Identity: 22% (95 aa)

VIGDGAYSTVMLATSIDTK------------KRYAAKVLNKEYLI-------------------------RQKKVKYVSIEKTALQKLN------NSPSV
..| |....| |.. . |.            ...|.|...|. |                          |.|. | |  |   ..||.      . | .
TLGRGSFGKVKLCIHKNTTGKERVHHIYTNGQKVAIKIIDKKKLKDKQNQDYSNCYKIDKSKCKHRYCWRRPKDRKNVRREIEIMKKLQGIGNKLDHPNI

VRLFSTFQD-------------------ESSLYFLL---EYAPNG----DFLSLMKKYGS---------------LDETCARYYAAQIIDAIDYLHSNGI
..|. ...|                   .. .|. .   ||...|    | ..  .. |.               ..|  ||.|  ||..|..|.||..|
IKLYEVYEDPHYFKNTNDYETSKQVFTKDKHMYMVMEIMEYCSGGELFDDLFDYIVEHGCYGEEFDQFDIVERGRFTEREARRYFRQICSAVHYCHSHNI

IHRDIKPENILLDGEM-----------------KIKLTDFGTAKLLNPTNNSVSKPEYD------------LSTRSKSFVGTAEYVS-PELLND------
.|||.||||||||  .                 .||..||| |. ..| .|.  ...|.                 | |.|| ||.. ||.||       
VHRDLKPENILLDDNNDDSDPVEHDEIFDWNNNNIKIIDFGFANKFDPGENNFMCSDYKGGEMHNQWTTPTEGQKMKTFCGTPEYMAAPEVLNGKGHCNM

--------SFTDYRCDIWAFGCILFQMIAGKPPFKAT-------------NEYLTFQKVMKVQYAFTPGFPLI------------------------IRD
           .. ||.|. |.||. |  |.||| .              |.| .|.|.|| .| | | .  .                         .|
QNATDEEKPYYGPKCDMWSCGVILYIMLCGYPPFYGDCDNEICEDEWIGMNDYELFEKIMKGKYDFPPPYFSPISCNYGPEWWDDISDEFHHFVSQECKD

LVKKILVKNLDRRLTISQIKEHHFF
|..|.|... ..|.||.|...| ..
LIRKMLQVDPEKRMTIEQCLNHPWM
Kinase PKH2.AA Pkinase 179-443 27 2.8e-82 284.46 Pfam 1-293 (293) Show / Hide 
Range on Protein: 179-443
Range on HMM: 1-293/293
Sequence Identity: 27% (83 aa)

FKFGSVIGDGAYSTVMLATSIDTKKRYAAKVLNKEYLIRQKKVKYVS-IEKTALQKLNNSPSVVRLFSTFQDESSLYFLLEYAPNG----DFLSLMK--K
...|..|| |....| ... ..| |..| |...|.    .|..  .   |   ...| |.| .|||. .|.|....|. .||...|    |  ....  .
YHIGRKIGSGSFGCVYKCHHKGTGKIVAVKIIKKRHEKSWKDQTHRRLSEIQIMKRL-NHPNIVRLYDWFEDKDHIYMVMEYCEGGLYVMDLFDYISTWR

YGSL--DETCARYYAAQIIDAIDYLHSNGIIHRDIKPENILLDGEMKI----KLTDFGTAKLLNPTNNSVSKPEYDLSTRSKSFVGTAEYVSPELLN-DS
.|..  .|  .. |. ||. ...|.||.||||||.||||||.| .. |    |..||| ||...          |  ..  ..|.|| .|..||... ..
HGCFYFSEWECKFYMYQILRGLEYCHSMGIIHRDLKPENILIDNNGHIDACVKICDFGLAKQFD----------Y-NNS-MTTFCGTPWYMAPEVIRGGQ

FTDYRCDIWAFGCILFQMIAGKPPFKAT------NEYLTFQKVMKVQYAFTPGFP---------------------LIIRDLVKKILVKNLDRRLTISQI
  ....|.|..||||..|. |.|||.        ...  ....|. .. |    .                        .|..|..| |.  .|.|. ||
YYGPKVDMWSCGCILYEMLCGRPPFPGHCWHDNHDQMQMICRIMGPPLHFDWPWWCSISYFFFRHWHFHWTFHNWSEECKDFIKWCLCKDPKKRPTAEQI

KEHHFF
..| .|
LQHPWF
Kinase PKH2.AA Ciliate-E2 179-443 23 4e-78 265.87 In-house 1-365 (365) Show / Hide 
Range on Protein: 179-443
Range on HMM: 1-365/365
Sequence Identity: 23% (88 aa)

FKFGSVIGDGAYSTVMLATSIDTKKRYAAKVLNKEY------------------LIRQKKVKYVSIEKTALQKLN---------------NSPSVVRLFS
.||  .|| |....| ... . ..|..| |. .  .                   .......... |.  ....|               |.| ..... 
YKFIKKIGQGNFGSVYKCKVWKVQKQFAIKIID-QKQQRQQMQEKVKIKIYAMKIMKKNQIEQIKQEIHIMREINCFYKKINEKNILEQLNHPNIIKMYE

TFQ--DESSLYFLLEYAPNGDFLSLMK------------KYGSLDETCARYYAAQIID---------------AIDYLHSNG-IIHRDIKPENILLDGEM
.||  |....|. .||.  || ....|            . ....|  ..|. .||..               |. ||||.. ||||||||||||.    
CFQEKDDNNIYLVMEYCQGGDLFDYIKNNKKKRNHEIEKD-KYFTEKEIKYIMKQILQGFKTKAEFYIACIILALEYLHSKNNIIHRDIKPENILF----

KIKLTDFGTAKLLN--PTNNSVSKPEYDLSTRSKS--------------------FVGTAEYVSPELLNDSFTD---------YRCDIWAFGCILFQMIA
 ||..|||..| ..    |..  |..  . .  |.                    ..||..|..|| ||    |         | ||||..|.||..|. 
-IKIIDFGLSKKYDDDNQNRTH-KQQCKWYMF-KNDTSRTPGYMDQIIQQNMFNTICGTPGYMAPEILNGKKYDNQQKQKGYDYKCDIWSLGVILYEMLF

GKPPFKATNEYLTFQKVMKVQYAFT------------------PGFPLIIRDLVKK----ILVKNLDRRLT-ISQIKEHHFF
|||||        .|. .. .. |                      ..   || ||    .|.|. . |.| ..||..|..|
GKPPF--------QQQIKQCKIDFPCPEWQKDTQCIQCKWKSWKKWSQECKDLIKKFGKRMLQKDPEKRITGWEQILNHPWF
Kinase PKH2.AA Ciliate-E2-Unclassified 179-443 24 2e-77 263.54 In-house 1-352 (352) Show / Hide 
Range on Protein: 179-443
Range on HMM: 1-352/352
Sequence Identity: 24% (87 aa)

FKFGSVIGDGAYSTVMLATSIDTKKRY-----AAKVLNKEYLIRQKKVKYVSIEKTALQKLN------------------NSPSVVRLFSTFQDESSLYF
.|.. .|| |....| ..  ...|  |     . |. ..  .. ..|    . |........                  ..| .|..| .|||.  .|.
YKIIKQIGQGGFGKVYKCQHKKQK-QYYAMKYMKKIQIYKQKQIMNKD-EIMNEMKEMNNKKKYHQRKYNKIMQQILLNHPHPFIVKMFYCFQDKQNIYI

LLEYAPNGDFLSLMKKYGS-----------------LDETCAR-----YYAAQIIDAIDYLHSNG-IIHRDIKPENILLDGEM---KIKLTDFGTAKLLN
 .||...|| .  .||...                 ..|  |.     .|.|||.....|||... ||||||||||||.| ..   .||..||| .| ..
VMEYCEGGDLWQYIKKRKKQKQKGNDLFHNMKQRKIFTEQQAKYKKAKFYFAQILQGLEYLHHKNNIIHRDIKPENILFDNNGKNYYIKIIDFGISKKYQ

PTNNSVSK---PEYDLS--TRSKSFVGTAEYV----SPELLNDSFTD----YRCDIWAFGCILFQMIAGKPPFKATNEYL----------------TFQK
  ||.  .   . ..     ....|.|| .|     .||.|     |    | ||||..|.||..|. |..||...|..                  .|.
QNNNCD-TNQQQKMQIWKQQMMWTFCGTPNYMPQYTAPEVLQGQNYDHSKAYKCDIWSLGVILYEMLFGYYPFYDNNCEQHQQLITQWINNAYRKQLYQN

VMKVQYAFTP--------GFPLIIRDLVK----KILVKNLDRRLTISQIKEHHFF
 .. .. | .        . .    |...    |.|.||.. |.|..||..|..|
IKQKNIQFPKFPWQQIPKHWSPEAKDFINDLLQKMLKKNPNKRITFEQILNHPWF
Kinase PKH2.AA RSK 181-443 30 1.3e-75 257.46 In-house 1-278 (278) Show / Hide 
Range on Protein: 181-443
Range on HMM: 1-278/278
Sequence Identity: 30% (88 aa)

FGSV--IGDGAYSTVMLATSIDTKKRYAAKVLNKEYLIRQKK-VKYVSIEKTALQKLNNSPSVVRLFSTFQDESSLYFLLEYAPNGDFLSLMKKYGS---
      .| |.....   |  ||.. || |||.|  ... .| ....  | . |.  ...| .|.|. .||.|. ||  .|| . |...   .| ..   
LKVLGQGGYGKVFLCRKCTHHDTGQIYAMKVLKKAKIVQRQKDTRHTMTERNILERCQQHPFIVTLHYAFQTEGKLYLIMEYCRGGELFTHLQKEKHFGC

LDETCARYYAAQIIDAIDYLHSNGIIHRDIKPENILLDG---EMKIKLTDFGTAKLLNPTNNSVSKPEYDLSTRSKSFVGTAEYVSPELLN----DSFTD
..|. |..|.|.|. |...||. ||||||.||||||.|    |  ||||||| .|..            | . . ..|..|.||. ||.|.    ..  |
FSEDEACFYMAEIVLAVEHLHQQGIIHRDLKPENILYDDESNEGHIKLTDFGFCKQF----------RCDHNQWTMTFCYTIEYMAPEMLKRANQQGGHD

YRCDIWAFGCILFQMIAGKPPFKA---TNEYLTFQKVMKVQYAFTPGFP------LIIRDLVKKILVKNLDRRLT-----ISQIKEHHFF
  ||.| .|.... | .|.|||..    |   ......| .  |....|         .||..| | ..  .||.     ...||.| .|
KACDWWSLGVLMYEMLTGCPPFQGPNDNNRKEIMKRIQKGK--FSLTMPNWQYLSQEAKDLIRKMLHRDPHKRLGCGPQDAEEIKQHPWF
Kinase PKH2.AA CAMKL 179-443 26 1.9e-69 220.74 In-house 1-297 (297) Show / Hide 
Range on Protein: 179-443
Range on HMM: 1-297/297
Sequence Identity: 26% (83 aa)

FKFGSVIGDGAYSTVMLATS-IDTKKRYAAKVLNKEYLIR-------------QKKVKYVSIEKTALQKLN--NSPSVVRLFSTFQDESS------LYFL
...| ..| |....| |||  . |....| |...|. .               ....  .  |   ...||    | ...|. ......       .|  
YRIGKTLGKGSFGKVKLATHIRTTGEKVAIKIIDKKKIWNDPWMKKNKCGQKHESDM-RIRREIQIMKMLNIGKHPNIIKLYEVIETPEHDIETKKIYLV

LEYAPNGD--FLSLMKKY----GSLDETCARYYAAQIIDAIDYLHSNGIIHRDIKPENILLDGEM--KIKLTDFGTAKL---LNPTNNSVSKPEYDLSTR
.||...|.   .   .|     |...|  || |  ||..|..|.||.||.||||||||||||  .  .||..||| . .                   ..
MEYCSGGEMDLFDYIVKHGHRRGRMPEHEARRYFRQIVSAVNYCHSHGIVHRDIKPENILLDENGNNNIKIIDFGFSNMYRPC-------------IFGP

SK---SFVGTAEYVSPELLND--SFTD-YRCDIWAFGCILFQMIAGKPPFKAT--------NEYLTFQKVMKVQYAFTPGFPL-IIRDLVKKILVKNLDR
 .    | |. .| .||....     | .  |||. | ||. |. |. ||..         |  . . |.|.  | ... . .   ||| .|.|..| ..
GQKLKTFCGSPPYMAPEIFQGNNKPYDGPKVDIWSCGVILYAMVCGYLPFDDDTYNKQGKDNI-YLYWKIMCG-YYPPIWYHVSDCRDLIRKMLQVNPEK

RLTISQIKEHHFF
| || ||..| ..
RPTIHQIMNHPWM
Kinase PKH2.AA AktR 179-443 33 2.8e-69 236.47 In-house 1-268 (268) Show / Hide 
Range on Protein: 179-443
Range on HMM: 1-268/268
Sequence Identity: 33% (93 aa)

FKFGSVIGDGAYSTVMLATSI-DTKKRYAAKVLNKEYLIRQKKVKYVSIEKTALQKLNNSPSVVRLFSTFQDESSLYFLLEYAPNGDFLSLMKKYGSLDE
|..  ..| ||...|.|..   |..| || |.. |. .|.... ...  |.. .....| |  |.|. .||... |.|..|| |.|. ..  || . ..|
FHVYKCLGKGAFGKVYLVQKKRDNQKQYAMKMIKKKKIIERNQMHHTITERNIMEMCCNHPFIVKLHYCFQTKEKLFFIMEYCPGGELFQHLKKKKKFSE

TCARYYAAQIIDAIDYLHSN-GIIHRDIKPENILLDGEMKIKLTDFGTAKLLNPTNNSVSKPEYDL--STRSKSFVGTAEYVSPELLND-SFTDYRCDIW
  || |.|||. |..|||..  || ||.|||||||| .  .|.|||| .|            . .   . . .||.|| ||..|| ..     .. .|.|
EQARFYFAQILLALEYLHQHMNIIYRDLKPENILLDEDGHVKITDFGLSK-----------LQFMMHYDEKAYSFCGTPEYMAPEMITKKKGHNKSVDWW

AFGCILFQMIAGKPPFKATNEYLTFQKVMKVQYAFTPGFPLII----RDLVK-KILVKNLDRRLT-----ISQIKEHHFF
|||. .. |..| ||| . |    |||  . |  . . .|  .    .||.. |.| ||   ||.     ...||.| .|
AFGIFIYEMVTGCPPFYHKNQNQMFQKIKIKQ-QNKFPYPSYFSSQCKDLIQRKLLCKNPNKRLGYYCNGWEEIKSHPWF
Kinase PKH2.AA MAST 179-443 27 5.2e-67 214.94 In-house 1-334 (334) Show / Hide 
Range on Protein: 179-443
Range on HMM: 1-334/334
Sequence Identity: 27% (93 aa)

FKFGSVIGDGAYSTVMLATSIDTKKRYAAKVLNKEYLIRQKKVKYVSIEKTALQKLNNSPSVVRLFSTFQDESSLYFLLEYAPNGDFLSLMKKYGSLDET
|.|  .|. |||  | |.  ..|..|.| ||..| ..|. . |. | .|...|  . | | || .|..|| .. |.. .||   ||. ||.. ||..|| 
FEFIKPISKGAYGKVYLVKHKKTNDRFAMKVIKKSDMINKNMVDQVQVERNILAMYQN-PFVVKMFYSFQTKNYLCMVMEYMEGGDCASLLHMYGYFDEW

CARYYAAQIIDAIDYLHSNGIIHRDIKPENILLDGEMKIKLTDFGTAKL--LNPTNNSVS----------------KPEYDLST----------------
 |. | |... ...|||| ||.|||.||.|.|.| .  ||||||| .|    . .|. ..                |.. | |                 
MAKMYIAETVLCLEYLHSHGIVHRDLKPDNMLIDSNGHIKLTDFGLSKVGFMDDLNMMYEGYTPPNIFNNSTDPMNKNQQDYSQFPGDFGINGNTNKNQI

--------------------RSKSFVGTAEYVSPELLNDSF-TDYRCDIWAFGCILFQMIAGKPPFKATNEYLTFQKVMKVQ---YAFTPG--------F
                    . |. .|| .| .||....        | |. | |... ..| |||   .  ..||.. .       . .|        .
QQQQEQPQCQQQNMRPHNIHQNKQCCGTPDYIAPEVILGQGTHGKPVDWWSMGIIMYEFLVGCPPFNDDTPEEIFQNILNRNCNEIEWPEGGDINDDEAM

PLIIRDLVKKILVKNLDRRLTIS----QIKEHHFF
.   .||..| |  .   ||. .    ..|.| ||
SPEAQDLIEKLLQPDPRKRLGANNGADEVKQHPFF
Kinase PKH2.AA PKA 179-326 42 2.7e-47 163.45 In-house 1-149 (263) Show / Hide 
Range on Protein: 179-326
Range on HMM: 1-149/263
Sequence Identity: 42% (64 aa)

FKFGSVIGDGAYSTVMLATSIDTKKRYAAKVLNKEYLIRQKKVKYVSIEKTALQKLNNSPSVVR-LFSTFQDESSLYFLLEYAPNGDFLSLMKKYGSLDE
|..  ..| | . .|||. . .... || |.|.|.. .| | |  |  ||. || ... | .|. . .||||.. ||...||.| |.  | . | |....
FEIIQTLGTGSFGRVMLCRHKHSGNYYAMKMLKKQEIVRLKQVEHVHNEKNILQNIKH-PFIVKKMYWTFQDDRYLYMVMEYVPGGEMFSYLRKSGRFSN

TCARYYAA-QIIDAIDYLHSNGIIHRDIKPENILLDGEMKIKLTDFGTAK
  |. ||| ||. |..||||  ||.|| ||||||.| .  ||.|||| ||
PHAKFYAASQIVLALEYLHSQNIIYRDLKPENILIDKNGHIKITDFGFAK
Kinase PKH2.AA TyrKc 179-443 21 1.6e-15 28.27 SMART 1-280 (280) Show / Hide 
Range on Protein: 179-443
Range on HMM: 1-280/280
Sequence Identity: 21% (62 aa)

FKFGSVIGDGAYSTVMLATSIDTKKRYAAKVLNKEYLIRQKKVKYVSIEKTALQKL-NNSPSVVRLFSTFQDE-------SSLYFLLEYAPNGDFLSLMK
 ..| ..| ||. .|...| .      | |.|...       ..    |   . ||  . | .|||.    ..         |. ..||.|.|| ..  .
ITLGKKLGEGAFGEVYKGTWK---IQVAVKMLKEDA------REDFMREARIMCKLGGHHPNIVRLYGVCTQQGRNFMYIEPLMIVMEYMPHGDLKDYLR

KYGS-LDETCARYYAAQIIDAIDYLHSNGIIHRDIKPENILLDGEMKIKLTDFGTAKLLNPT-NNSVSKPEYDLST-RSKSFVGTAEYVSPELLNDSFTD
|..  |      ... || .  .||||...||||.   |.|.. .  .| .||| .. .    .. .||  |. .. ... ..      .|| .|..   
KHRPKLCMKDLLSFCWQIACGMEYLHSKNCIHRDLAARNCLVGENHTVKISDFGLSRDIYDDDQQGESKDYYRKKEHKGGKTMLPIRWMAPECINYGKFT

YRCDIWAFGCILFQMIA-GKPPFKA-----TNEYLTFQKVMKVQYAFTPGF---------PLIIRDLVKKILVKNLDRRLTISQIKEHHFF
   |.|.||  .. .   |..|         . .  ...|..  .   |           |  . .. |.    . . | | |.|  |..|
TKSDVWSFGVCMWEIFTYGQQPYPGMIQQMMSNQEVIEYVKQGYRMPQPPNDYPMSFVCCPDEMYQIMKQCWHEDPEDRPTFSEI--HECF
Kinase PKH2.AA PKA 371-443 28 3.9e-14 53.3 In-house 181-263 (263) Show / Hide 
Range on Protein: 371-443
Range on HMM: 181-263/263
Sequence Identity: 28% (24 aa)

DIWAFGCILFQMIAGKPPFKAT--NEYLTFQKVMKVQYAFTPGFPLII---RDLVKKILVKNLDRRL-TISQ----IKEHHFF
| ||.|.. . | ||.||| ..  .   ...|  . .. | . |       .||.|| |...| .|. . ..    ||.| .|
DWWALGILIYEMLAGYPPFYDHNRDPMQIYEKICNGKIKFPRHFDSDANYFKDLIKKLLQVDLTKRYGNMKNGVNDIKNHKWF
Kinase PKH2.AA Pkinase_Tyr 248-323 32 5.7e-08 27.62 Pfam 76-156 (270) Show / Hide 
Range on Protein: 248-323
Range on HMM: 76-156/270
Sequence Identity: 32% (26 aa)

QDES-SLYFLLEYAPNGDFLSLMKKY----GSLDETCARYYAAQIIDAIDYLHSNGIIHRDIKPENILLDGEMKIKLTDFG
|.|. ..|  .||.|.|| |.  .|     ..|.      ...|| .. .||.|...||||.   |.|.. ....| .|||
QGEPNQIYIVMEYMPHGDLLDYLRKHREDKQPLTMKDLLQMCWQIAKGMEYLESKNCIHRDLAARNCLVTENNVVKICDFG
Kinase PKH2.AA Pkinase_Tyr 179-197 36 1.978621 2.08 Pfam 1-19 (270) Show / Hide 
Range on Protein: 179-197
Range on HMM: 1-19/270
Sequence Identity: 36% (7 aa)

FKFGSVIGDGAYSTVMLAT
 .|| ..| ||. .|...|
ITFGKKLGEGAFGEVYKGT
PDK1_PH_fungi PKH2.AA PDK1_PH_fungi 861-955 44 1.2e-53 172.38 In-house 1-100 (100) Show / Hide 
Range on Protein: 861-955
Range on HMM: 1-100/100
Sequence Identity: 44% (45 aa)

KYYKRTIVMTSFGRFLVFAKRRQPNPVTNLKYELEYDINLRQQGTKIKELIIPLEMGTNHI------VVIQTPYKSFLLSTDKKTTSKLFTVLKKILNSN
||||...|.|..||.|.|.||..|||.|||.|.|.|.|||.|...|||||..|  ......      .|||||||||.....|..... ...|||. ..|
KYYKCMMVITTHGRCLIFTKRNKPNPWTNLNYDLCYEINLNQPFVKIKELVSPQ-TKFQKMMPSTGIFVIQTPYKSFVFECEKFDVNQWTWALKKSIKNN

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