Gene PRR2 (Bakers Yeast)

PRR2

Species: Bakers Yeast
Alias: PRR2
External Links: Saccharomyces Genome Database Link ,
Annotation:

Classification

Group: Other
Family: HAL

Sequence

Name Sequence Type Origin Length Description Download
PRR2.AA Protein Refseq_NP 699 Prr2p [Saccharomyces cerevisiae] Fasta, JSON
PRR2.kin_dom Protein Kinase Domain Sugen global kinase HMM prediction 293 Kinase domain by global Sugen HMM Fasta, JSON

Protein domain

Protein domains of PRR2.AA. The domains are annotated by HMM profiles from Pfam and SMART, as well as in-house data which includes HMMs of each individual kinase group, family and subfamily. Here is domain list in details, including sequence identity, significance and alignment. In particular, you can find can find the best hit kinase group/family/subfamily, which is helpful to understand the relationship between kinases.Kinase domain and best hit kinase group/family/subfamily are highlighted in red and blue. Visualized by pviz.

Usage: Zoom in selected region by dragging mouse and zoom out by double-clicking.

Show/hide domain list
Domain Protein name Domain Name Range Identity (%) Significance Score Profile Source Profile Range (length) Alignment
Kinase PRR2.AA HAL 361-653 41 4.5e-194 651.04 In-house 1-363 (363) Show / Hide 
Range on Protein: 361-653
Range on HMM: 1-363/363
Sequence Identity: 41% (150 aa)

RDLDVVLGEGSGGKVKLVQRV--------------LDNKVFALKEYR-SKKKRESERKYIKNIISEYCIASTLKN---------------PNICETLEIL
.....|||.|..|.||..||.               |.||||.||.| ..|..||..||.|...||.||..||..               |||||||.|.
GKCNKVLGWGAYGEVKICQRCRNKKDVPPYDTYHYRDKKVFAVKEFRKPMKYNESPEKYCKKCTSEFCIGHTLHHHHFNAKKPPKHVVHIPNICETLDIF

YEK---GKIFQILEYCEY-DLFSLVMSE----------KMHYEEICCLFKQLINGVKYLHDIGLSHRDLKLDNCVVTRRGILKLIDFGASSVFHYP---L
|..   .|.....|||.| |||..||..          ||||.||||.||||..||||.||.|..|||||..|||.|..||.||.|||.|..||||   .
YDSYTTDKWCEVMEYCPYGDLFAMVMRNGGKSRLKGWRKMHYMEICCCFKQLCHGVKYMHDMGIAHRDLKPENCVMTPDGICKLCDFGISDWFHYPPHDW

SSQMIEANGIVGSDPYLSPEVFYFN-----------EYDPRALDVWSVGIIFFCMITRRFPWKYPKVKDVQFKAFCSGRGVSSFKDLVTR----PATDDS
........|||||||||.|||.||.           |||||..|.||.|||..|||..|||||.|...|..|..||.......|...|||    |.....
EKNVHMCHGIVGSDPYLAPEVMYFDEKKHYDEKFQQEYDPRCVDCWSCGIIYCCMIMKRFPWKIPCKEDDSFRMFCYHYDCFIFHHNVTRTQEFPEKGCY

NNYD--------NDGYEEGVIDMGPNFILHRLPEETHKIMRRILEVSPFRRITINGILQDGWI
....        |.........|||..|.|.||.....||.|.|...|..|||...|..|.|.
HPFEEMEPENTPNNVQGKNNVNMGPHHIRHFLPHHCRHIMWRMLDWEPAKRITMDDIFNDPWM
Kinase PRR2.AA Pkinase 361-653 22 1.6e-59 208.88 Pfam 1-293 (293) Show / Hide 
Range on Protein: 361-653
Range on HMM: 1-293/293
Sequence Identity: 22% (72 aa)

RDLDVVLGEGSGGKVKLVQRVLDNKVFALKEYRSKKKRESERKYIKNIISEYCIASTLKNPNICETLEILYEKGKIFQILEYCEY-----DLFSLVM---
  .  ..|.|| |.|.. ... ..|..|.|. . ..........  .. || .|   |. |||...... ..|..|  ..||||      |||....   
YHIGRKIGSGSFGCVYKCHHKGTGKIVAVKIIKKRHEKSWKDQTHRRL-SEIQIMKRLNHPNIVRLYDWFEDKDHIYMVMEYCEGGLYVMDLFDYISTWR

SEKM--HYEEICCLFKQLINGVKYLHDIGLSHRDLKLDNCVVTRRGIL----KLIDFGASSVFHYPLSSQMIEANGIVGSDPYLSPEVFYFNEYDPRALD
. ..   ..|... ..|.. |..|.|. |  |||||..|. . ..| .    |..||| . .|   . ..   .....|. .|..|||  ...|.... |
HGCFYFSEWECKFYMYQILRGLEYCHSMGIIHRDLKPENILIDNNGHIDACVKICDFGLAKQFD--Y-NNS--MTTFCGTPWYMAPEVIRGGQYYGPKVD

VWSVGIIFFCMITRRFPWKYPK----VKDVQFKAFCSGRG------------VSSFKDLVTRPATDDSNNYDNDGYEEGVIDMGPNFILHRLPEETHKIM
.||.|.|...|...|.|..  .      . | . .|  .|            .| |. . . . .                   . .  |...||  ...
MWSCGCILYEMLCGRPPFP-GHCWHDN-HDQMQMICRIMGPPLHFDWPWWCSISYFF-FRH-W-H-----------------F-HWTF-HNWSEECKDFI

RRILEVSPFRRITINGILQDGWI
...|.. | .|.|.  |||. |.
KWCLCKDPKKRPTAEQILQHPWF
Kinase PRR2.AA S_TKc 361-653 18 3.6e-58 200.49 SMART 1-231 (231) Show / Hide 
Range on Protein: 361-653
Range on HMM: 1-231/231
Sequence Identity: 18% (57 aa)

RDLDVVLGEGSGGKVKLVQRVLDNKVFALKEYRSKKKRESERKYIKNIISEYCIASTLKNPNICETLEILYEKGKIFQILEYCEY---DLFSLVMSEK--
 ..  ..|.|. |||.... . .....|.|. .            ..|..|  | .  . |||.  ... .. .... ..|||.    |||..  . .  
YEILRKIGKGAFGKVYKCRHKKTGRIVAIKIIK------------EHIRREIQILKK-HHPNIVKLYDVFQD-DHLYMVMEYCDGDLGDLFDYIKKRGRH

-----MHYEEICCLFKQLINGVKYLHDIGLSHRDLKLDNCVVTRRGILKLIDFGASSVFHYPLSSQMIEANGIVGSDPYLSPEVFYFNEYDPRALDVWSV
     ..  .......|......|.|. |  ||||| .|  ...   .|..||| . ..           . ..|.  |..|||.    |.... |.||.
GLRFPFPE-HARFYMYQICCALEYCHSHGIIHRDLKPENILLDE--HIKICDFGLARQL-----------TTFCGTPWYMAPEVL---GYGKCKCDWWSC

GIIFFCMITRRFPWKYPKVKDVQFKAFCSGRGVSSFKDLVTRPATDDSNNYDNDGYEEGVIDMGPNFILHRLPEETHKIMRRILEVSPFRRITINGILQ-
|.|.. |.... |.      .. ||  .                                            ..|   ..|..|.. | .|.|.  .|| 
GCILYEMLCGYPPFP---QMQMMFKKIG--------------------------------------------SPEAKDFIRKCLQKDPEKRPTA-EALQD

------DGWI
      . |.
EWDIKCHPWF
Kinase PRR2.AA CAMK 366-653 16 2.3e-51 163.39 In-house 1-425 (425) Show / Hide 
Range on Protein: 366-653
Range on HMM: 1-425/425
Sequence Identity: 16% (74 aa)

VLGEGSGGKVKLVQRVLDN------------KVFALKEYRSKKKRESE-----------------------RKYIKNIISEYCIAST-------LKNPNI
.||.|| |||||... ...            . .| | .  || ....                        |  ||. .|..| ..       |. |||
TLGRGSFGKVKLCIHKNTTGKERVHHIYTNGQKVAIKIIDKKKLKDKQNQDYSNCYKIDKSKCKHRYCWRRPKDRKNVRREIEIMKKLQGIGNKLDHPNI

CETLEILYEKG-------------------KIFQIL---EYCEY-----DLFSLVMSE----------------KMHYEEICCLFKQLINGVKYLHDIGL
.  .|.   .                    ... ..   |||.      |||. . .                 ... .| . .|.|.. .|.|.|. . 
IKLYEVYEDPHYFKNTNDYETSKQVFTKDKHMYMVMEIMEYCSGGELFDDLFDYIVEHGCYGEEFDQFDIVERGRFTEREARRYFRQICSAVHYCHSHNI

SHRDLKLDNCVVTRR-----------------GILKLIDFGASSVFHY-------------------PLSSQMIEANGIVGSDPYLS-PEVFYF------
 |||||..|  .. .                 . .|.|||| . .|                     . . .    .  .|. .| . |||.        
VHRDLKPENILLDDNNDDSDPVEHDEIFDWNNNNIKIIDFGFANKFDPGENNFMCSDYKGGEMHNQWTTPTEGQKMKTFCGTPEYMAAPEVLNGKGHCNM

-------NEYDPRALDVWSVGIIFFCMITRRFPWKYP--------------------KVKDVQFK-AFCS------------GRGVSSFKDLVTRPATDD
       ..|.... |.||.|.| . | . ..|.  .                    |..  ..                    ..|             
QNATDEEKPYYGPKCDMWSCGVILYIMLCGYPPFYGDCDNEICEDEWIGMNDYELFEKIMKGKYDFPPPYFSPISCNYGPEWWDDISDE-----------

SNNYDNDGYEEGVIDMGPNFILHRLPEETHKIMRRILEVSPFRRITINGILQDGWI
                   |  | . .|     |..|.| | .|.||  .|.. |.
-------------------F-HHFVSQECKDLIRKMLQVDPEKRMTIEQCLNHPWM
Kinase PRR2.AA CAMKL 360-653 22 2.5e-47 148.99 In-house 1-297 (297) Show / Hide 
Range on Protein: 360-653
Range on HMM: 1-297/297
Sequence Identity: 22% (77 aa)

YRDLDVVLGEGSGGKVKLVQR-VLDNKVFALKEYRSKKKRESERKYIK----------NIISEYCIASTLK---NPNICETLEILYEKGK------IFQI
|| .. .||.|| ||||| .   . ..  | | .  ||... . .  .          .|  |..| . |.    |||.  .|... . .      |. .
YRIGK-TLGKGSFGKVKLATHIRTTGEKVAIKIIDKKKIWNDPWMKKNKCGQKHESDMRIRREIQIMKMLNIGKHPNIIKLYEVIETPEHDIETKKIYLV

LEYCE-YD--LFSLVMSE-----KMHYEEICCLFKQLINGVKYLHDIGLSHRDLKLDNCVVTRRG--ILKLIDFGASSVFH-YPLSSQMIEANGI-----
.|||.  .  ||  . ..     .|. .| . .|.|.. .|.|.|. |  |||.|..|  .. .|   .|.|||| |  .  .      |  .|      
MEYCSGGEMDLFDYIVKHGHRRGRMPEHEARRYFRQIVSAVNYCHSHGIVHRDIKPENILLDENGNNNIKIIDFGFSNMYRPC------IFGPGQKLKTF

VGSDPYLSPEVFYF--NEYDPRALDVWSVGIIFFCMITRRFPWKYPKVKDVQFKAFCSGRGVSSFKDLVTRPATDDSNNYDNDGYEEGVIDMGPNFILH-
 || || .||.|     .|| .. |.|| |.| . |.. ..|.. . ..                             . ...  ..  ..|.  .    
CGSPPYMAPEIFQGNNKPYDGPKVDIWSCGVILYAMVCGYLPFDDDTYN-K---------------------------QGKDNI-YLYWKIMCG-YYPPI

--RLPEETHKIMRRILEVSPFRRITINGILQDGWI
  ... . . . |..|.| | .|.||  |... | 
WYHVS-DCRDLIRKMLQVNPEKRPTIHQIMNHPWM
Kinase PRR2.AA Ciliate-E2 361-653 16 4e-43 145.88 In-house 1-365 (365) Show / Hide 
Range on Protein: 361-653
Range on HMM: 1-365/365
Sequence Identity: 16% (68 aa)

RDLDVVLGEGSGGKVKLVQRVLDNKVF------------------ALKEYRSKKKRESERKYIKNIISEY-CIA------------STLKNPNICETLEI
 ..  ..|.|. |.|..... ...| |                  . |.|  | ..... ..||..|... .|             ..|..|||..  | 
YKFIKKIGQGNFGSVYKCKVWKVQKQFAIKIIDQKQQRQQMQEKVKIKIYAMKIMKKNQIEQIKQEIHIMREINCFYKKINEKNILEQLNHPNIIKMYEC

LY--EKGKIFQILEYCEY-DLFSLV-------------MSEKMHYEEICCLFKQLIN---------------GVKYLHDIG-LSHRDLKLDNCVVTRRGI
 .   . .|. ..|||.. |||..                ...  .||. ..||...               ...|||  .   |||.|..| ..     
FQEKDDNNIYLVMEYCQGGDLFDYIKNNKKKRNHEIEKD-KYFTEKEIKYIMKQILQGFKTKAEFYIACIILALEYLHSKNNIIHRDIKPENILF-----

LKLIDFGASSVFHYP--------LSSQMIEANG--------------------IVGSDPYLSPEVFYFNEYDP--------RALDVWSVGIIFFCMITRR
.|.|||| |  .. .        ..  ... ..                    |.|. .|..||..   .||          . |.||.|.|...|.. .
IKIIDFGLSKKYDDDNQNRTHKQQCKWYMF-KNDTSRTPGYMDQIIQQNMFNTICGTPGYMAPEILNGKKYDNQQKQKGYDYKCDIWSLGVILYEMLFGK

FPWKYPKVKDVQFKAFCSGRGVSSFKDLVTRPATDDSNNYDNDGYEEGVIDMGPNF-------------ILHRLPEETHKIMRR----ILEVSPFRRIT-
.|.                                       .  ... ||  ...             . . ...|.  ....    .|.. |  ||| 
PPF--------------------------------------QQQIKQCKIDFPCPEWQKDTQCIQCKWKSWKKWSQECKDLIKKFGKRMLQKDPEKRITG

INGILQDGWI
.. ||.  |.
WEQILNHPWF
Kinase PRR2.AA Ciliate-E2-Unclassified 360-653 15 9e-40 135.63 In-house 1-352 (352) Show / Hide 
Range on Protein: 360-653
Range on HMM: 1-352/352
Sequence Identity: 15% (61 aa)

YRDLDVVLGEGSGGKVKLVQRVLDNKVF-------ALKEYRSKKKRESERKYIKNIISEYCIA---------------STLKNPNICETLEILYEKGKIF
|. .  ..|.|. |||...|.  ..  .         ..| .|......  .. ... . ..                . ...|.|   ...   | .|.
YKIIK-QIGQGGFGKVYKCQHKKQK-QYYAMKYMKKIQIYKQKQIMNKD-EIMNEMKEMNNKKKYHQRKYNKIMQQILLNHPHPFIVKMFYCFQDKQNIY

QILEYCEYDLFSLVMSEKMH---------------Y---EEICC------LFKQLINGVKYLHDIG-LSHRDLKLDNCVVTRRG---ILKLIDFGASSVF
 ..||||.   .  ......                   |. ..      .|.|...| .|||  .   |||.|..| ...  |    .|.|||| |.  
IVMEYCEGGDLWQYIKKRKKQKQKGNDLFHNMKQRKIFTEQQAKYKKAKFYFAQILQGLEYLHHKNNIIHRDIKPENILFDNNGKNYYIKIIDFGISKKY

HYPLSSQMIE------------ANGIVGSDPYL----SPEVFYFNEYDPR---ALDVWSVGIIFFCMITRRFPWKYPKVKD---------------VQFK
 ..  ..  .            .. ..|.  |.    .|||.  ..|| .   . |.||.|.|...|.. ..| .... ..                ...
QQNNNCD-TNQQQKMQIWKQQMMWTFCGTPNYMPQYTAPEVLQGQNYDHSKAYKCDIWSLGVILYEMLFGYYPFYDNNCEQHQQLITQWINNAYRKQLYQ

AFCSG-------------RGVS-SFKDLVTRPATDDSNNYDNDGYEEGVIDMGPNFILHRLPEETHKIMRRILEVSPFRRITINGILQDGWI
 .. .              ..| . ||...                                    ......|.. |  |||.. ||.  |.
NIKQKNIQFPKFPWQQIPKHWSPEAKDFIN------------------------------------DLLQKMLKKNPNKRITFEQILNHPWF
Kinase PRR2.AA CHK1 465-577 30 2.5e-24 82.23 In-house 111-230 (276) Show / Hide 
Range on Protein: 465-577
Range on HMM: 111-230/276
Sequence Identity: 30% (37 aa)

FKQLINGVKYLHDIG-LSHRDLKLDNCVVTRRG------ILKLIDFGASSVFH-YPLSSQMIEANGIVGSDPYLSPEVFYFNEYDPRALDVWSVGIIFFC
|||||.|.||.|..|   |||.|..|   . ..      .||. ||| ....  .    .| ...   |. ||  |||.. ..|   . |.|| |.. . 
FKQLISGLKYIHCCGGVTHRDIKPENLLLDKHDSNDMPDNLKIADFGLATWYRRHDGEERMLDKR--CGTPPYMAPEVCTGKQYRGPPVDIWSCGVVLMA

MITRRFPWKYPK-VKDVQFKAF
|.|.  ||. |.   . .....
MLTGELPWDQPSHMDCQEYCWW
Kinase PRR2.AA STE 361-569 17 8.7e-24 80.95 In-house 1-276 (359) Show / Hide 
Range on Protein: 361-569
Range on HMM: 1-276/359
Sequence Identity: 17% (49 aa)

RDLDVVLGEGSGGKVKLVQRVL---------------DNKVFALKEYRSKKKRESERK-------------YIKNIISEYCIASTLK--NPNICETLEIL
 ..  ..|.|..|.| .  ..                 ....| |. . .... .. .              ...|. |  | . ..   ||| . .   
WEGIEKIGKGAFGTVYKAMNHKNCNIHKTGEVENNGETGEIMAIKQMNLENCNNKD-ENQENQELENKNHEEMQQILKEIKIMKKCNHMHPNIVKYYGCY

YEKG-------KIFQILEYCEYDLFSLVMSEKMHY----------------EEICCLFKQLING-VKYLHDIGLSHRDLKLDNCVVTRRGILKLIDFGAS
. .|       ... ..||...  .. .. .|.                  ..|..  .|.. |  .|||. .  |||.| .|  .      ||.||| .
FKEGHNHKNDDELWICMEYMDGGSLDDIIKHKYGCGKPLNHNRQHQHRFPESQIAYICRQILKGLLYYLHSHHIIHRDIKPANILL-----VKLCDFGVC

S--VFHYPLSSQMI------------EANGIVGSDPYLSPEVFY------FNEYDPRALDVWSVGIIFFCMITRRFPW---KYPKV
.  . ... . | .            . | .||.  . .|||         ..|| .. |.||.|.    |.| . ||   .....
GQLTDSMANI-Q-SNNIIDCIETMQQKRNTFVGTP-WMAPEVIQQNGQGRDKGYDTKC-DIWSLGCTIIEMATGKPPWHDMHPMRA
Kinase PRR2.AA MELK 362-564 26 3.4e-22 72.39 In-house 2-200 (254) Show / Hide 
Range on Protein: 362-564
Range on HMM: 2-200/254
Sequence Identity: 26% (55 aa)

DLDVVLGEGSGGKVKLVQRVLDNKVFALKEYRSKKKRESERKYIKNIISEYCIASTLKNPNICETLEILYEKGKIFQILEYCE-YDLFSLVMS-EKMHYE
..   .| |  .||||   .| |.  |.|    |..  ..   .  .  |      |.  .||.   ..  . ||| ..|||   ..|  ... .... |
EVHDEIGTGGFAKVKLACHILTNQMVAIK-IMDKNQLGHD---LPRVKTEMDALKNLRHQHICQLYHYIETEDKIFMVMEYCPGGEMFDYIIRQDRLEEE

EICCLFKQLINGVKYLHDIGLSHRDLKLDNCVVTRRGILKLIDFGASSVFHYPLSSQMIEANGIVGSDPYLSPEVFYFNEYDPRALDVWSVGIIFFCMIT
|   .|.|..  . |.|  | .||||| .| ...    |||||||  .          ..     ||  |  ||.    .|     ||||.||. . .. 
ETRHFFRQIVSAIAYVHSQGYAHRDLKPENLLFDEDHHLKLIDFGLCAKTKGRKDYHNLQT--CCGSPAYAAPELIQGKQYIGSEADVWSMGILLYVLMC

RRFPW
   |.
GFLPF
Kinase PRR2.AA TSSK 417-504 34 1.8e-18 57.22 In-house 72-168 (289) Show / Hide 
Range on Protein: 417-504
Range on HMM: 72-168/289
Sequence Identity: 34% (33 aa)

TLKNPNICETLEILYEKG-KIFQILEYCEY-DLFSLVMSE------K-MHYEEICCLFKQLINGVKYLHDIGLSHRDLKLDNCVVTRRGILKLIDFG
|||.|||....|..     ||. ..||.|  ||.. .         . .| |.   .|.|.. .|||.|...  |||||. |    ... .||.|||
TLKHPNIIQFYEMFETCQGKIYMVMEYAEHGDLLEYIQRRTQERCCGALHEEQARKWFRQMVSAVKYCHSHNVVHRDLKCENILLDKHWNIKLTDFG
Kinase PRR2.AA MARK 366-504 29 6.4e-15 45.37 In-house 6-151 (262) Show / Hide 
Range on Protein: 366-504
Range on HMM: 6-151/262
Sequence Identity: 29% (43 aa)

VLGEGSGGKVKLVQRVLDNKVFALKEYRSKKKRESERKYIKNIISEYCIASTLKNPNICETLEILY--EKGK-IFQILEYCE-YDLFSLVMSE---KMHY
..|.|| .||||.. .. .. .|.| |  .|.. .. . .||. .|  | . |. ||| . ...    .... |. |.||..  .|.. . .    ..| 
TIGHGSYAKVKLACHKHTGRKVAIKIY--EKFKLNDPQWMKNVMREIEIMKKLDHPNIIKLFHVIEQDTEQHQIYLIMEYASGGELYDYIKAHPNGRLHE

EEICCLFKQLINGVKYLHDIGLSHRDLKLDNCVVTRRG--ILKLIDFG
||   .|.|.. .|.|.|...  |||.|..|  .  .|    |.||||
EEARRIFRQIVSAVNYCHSKNIVHRDIKPENILIDENGNHNIKIIDFG
Kinase PRR2.AA MARK 525-653 23 3.9e-12 36.13 In-house 167-262 (262) Show / Hide 
Range on Protein: 525-653
Range on HMM: 167-262/262
Sequence Identity: 23% (31 aa)

GSDPYLSPEVFYFNEYDPRALDVWSVGIIFFCMITRRFPWKYPKVKDVQFKAFCSGRGVSSFKDLVTRPATDDSNNYDNDG--YEEG--VIDMGPNFILH
|. || .||.|   .|| .. |.|| |.. . |.. .||..                                     .|.  |.|    |  |   | .
GTPPYMAPEIFLKKPYDGPKVDIWSLGVVLYFMVCGYFPFD-------------------------------------GDTQDYKELYKKILRGKYDIPC

RLPEETHKIMRRILEVSPFRRITINGILQDGWI
... | ... .|.| | | .|.||  |... |.
HVSKECRNLIQRLLTVNPEERPTIEEIMKHPWM
Kinase PRR2.AA TyrKc 361-656 17 2.4e-08 -87.6 SMART 1-280 (280) Show / Hide 
Range on Protein: 361-656
Range on HMM: 1-280/280
Sequence Identity: 17% (59 aa)

RDLDVVLGEGSGGKVKLVQRVLDNKVF--ALKEYRSKKKRESERKYIKNIISEYCIASTL--KNPNICETLEILYEK-------GKIFQILEYCEY-DLF
  |. .||||  |.| . .     .|    |||.            .. ...|  | . |  ..|||   . .  ..       . .. ..||... || 
ITLGKKLGEGAFGEVYKGTWK--IQVAVKMLKEDA-----------REDFMREARIMCKLGGHHPNIVRLYGVCTQQGRNFMYIEPLMIVMEYMPHGDLK

SLVMSEK--MHYEEICCLFKQLINGVKYLHDIGLSHRDLKLDNCVVTRRGILKLIDFGASSVFHYPL-----SSQMIEANGIVGSDP-----YLSPEVFY
.   . .     .. .    |  .|  |||. .. ||||   || |..... |  |||  | ..|       |.... . .  |..       ..||.. 
DYLRKHRPKLCMKDLLSFCWQIACGMEYLHSKNCIHRDLAARNCLVGENHTVKISDFGL-SRDIYDDDQQGESKDYYRKKEHKGGKTMLPIRWMAPECIN

FNEYDPRALDVWSVGIIFFCMITR-RFPWKYP---KVKDVQFKAFCSGRGVSSFKDL----VTRPATDDSNNYDNDGYEEGVIDMGPNFILHRLPEETHK
.... . . |||| |.  . . |.   |.  .   .... .  ..   ..     .                                |   . |.| ..
YGKFTT-KSDVWSFGVCMWEIFTYGQQPYPGMIQQMMSNQEVIEYVKQGYRMPQPPNDYPMS--------------------------F--VCCPDEMYQ

IMRRILEVSPFRRITINGILQDGWIKEI
||..  .  |  | | . |     ....
IMKQCWHEDPEDRPTFSEI-----HECF
Kinase PRR2.AA TSSK 525-559 42 4.9e-05 12.45 In-house 190-224 (289) Show / Hide 
Range on Protein: 525-559
Range on HMM: 190-224/289
Sequence Identity: 42% (15 aa)

GSDPYLSPEVFYFNEYDPRALDVWSVGIIFFCMIT
||  | .||..  ..||| . |||| |.| . | .
GSYAYAAPEILRGIPYDPKWYDVWSMGVILYIMVC
Kinase PRR2.AA TSSK 629-653 32 7.2e-05 11.89 In-house 265-289 (289) Show / Hide 
Range on Protein: 629-653
Range on HMM: 265-289/289
Sequence Identity: 32% (8 aa)

IMRRILEVSPFRRITINGILQDGWI
..|..|. .| .|..|| |. . |.
LIRHMLQPHPCNRPHINEICHHCWM
Kinase PRR2.AA MELK 622-653 31 0.00013 11.34 In-house 223-254 (254) Show / Hide 
Range on Protein: 622-653
Range on HMM: 223-254/254
Sequence Identity: 31% (10 aa)

LPEETHKIMRRILEVSPFRRITINGILQDGWI
|  |. ...|..| | | .|| .  .|.  |.
LSPESKQLLRHMLQVDPKKRISMKNLLNHPWV
Kinase PRR2.AA CHK1 631-653 43 0.001572 8.6 In-house 254-276 (276) Show / Hide 
Range on Protein: 631-653
Range on HMM: 254-276/276
Sequence Identity: 43% (10 aa)

RRILEVSPFRRITINGILQDGWI
| || ..|  |.||  | .| | 
RKILCENPNKRATIEQIEKDPWY