Gene SCH9 (Bakers Yeast)

SCH9

Species: Bakers Yeast
Alias: SCH9
External Links: Saccharomyces Genome Database Link ,
Annotation:

Classification

Group: AGC
Family: Akt

Sequence

Name Sequence Type Origin Length Description Download
SCH9.kin_dom Protein Kinase Domain Sugen global kinase HMM prediction 260 Kinase domain by global Sugen HMM Fasta, JSON
SCH9.AA Protein Refseq_NP 824 `protein kinase involved in growth control, may be redundant with cAMP pathway; Sch9p [Saccharomyces cerevisiae]` Fasta, JSON

Protein domain

Protein domains of SCH9.AA. The domains are annotated by HMM profiles from Pfam and SMART, as well as in-house data which includes HMMs of each individual kinase group, family and subfamily. Here is domain list in details, including sequence identity, significance and alignment. In particular, you can find can find the best hit kinase group/family/subfamily, which is helpful to understand the relationship between kinases.Kinase domain and best hit kinase group/family/subfamily are highlighted in red and blue. Visualized by pviz.

Usage: Zoom in selected region by dragging mouse and zoom out by double-clicking.

Show/hide domain list
Domain Protein name Domain Name Range Identity (%) Significance Score Profile Source Profile Range (length) Alignment
C2 SCH9.AA C2 184-397 14 2.2e-17 65.02 SMART 1-92 (92) Show / Hide 
Range on Protein: 184-397
Range on HMM: 1-92/92
Sequence Identity: 14% (32 aa)

KLEVTIIEARDLVTRSKDSQPYVVCTFESSEFISNGPESLGAINNNNNNNNNNQHNQNQHINNNNENTNPDAASQHHNNNSGWNGSQLPSIKEHLKKKPL
.|.|.|||||.|        |||. .                                                                          
TLTVHIIEARNLP------DPYVKVY--------------------------------------------------------------------------

YTHRSSSQLDQLNSCSSVTDPSKRSSNSSSGSSNGPKNDSS--HPIWHH---KTTFDVLGSHSELDISVYDAAHDHMFLGQVRLYPMIHNLAHASQHQWH
                                ..  ||  |  .|.|..   . .|||    . | ..|.|      |.|.... |.  | .|  .|||.
-------------------------------KTKVVKNTLSGFNPVWNEWMETFYFDVHP--Q-LRFEVWDH----DFIGHCCIPPN--N-PH--WHQWD

SLKPRVIDEVVSGDILIKW
.  .. ....  |.   .|
G--CIHLSDIL-GYRH-WW
C2 SCH9.AA C2 185-210 36 0.000634 15.84 Pfam 1-30 (90) Show / Hide 
Range on Protein: 185-210
Range on HMM: 1-30/90
Sequence Identity: 36% (11 aa)

LEVTIIEARDLVT----RSKDSQPYVVCTF
|.|..||||.|      ..  | |||....
LRVHVIEARNLPPMDWDKNGKSDPYVKVYL
C2 SCH9.AA C2 320-361 23 0.013677 11.29 Pfam 45-90 (90) Show / Hide 
Range on Protein: 320-361
Range on HMM: 45-90/90
Sequence Identity: 23% (11 aa)

KNDSSHPIWHHKTTFD-VLGSHSE-LDISVYDAAHD--HMFLGQVR
......|.|. . ||| .. .  . | ..|.|   .  . |.||..
IKNTLNPVWNETFTFDVPPPDLQHTLRFTVWDWDRFGRDDFIGQCC
Kinase SCH9.AA Akt 412-671 54 2.2e-191 617.12 In-house 1-264 (264) Show / Hide 
Range on Protein: 412-671
Range on HMM: 1-264/264
Sequence Identity: 54% (145 aa)

FEVLRLLGKGTFGQVYQVKKKDTQRIY-AMKVLSKKVIVKKNEIAHTIGERNILVTTASKSSPFIVGLKFSFQTPTDLYLVTDYMSGGELFWHLQKEGRF
|..|..||||.||.|..|||||||..| |||||.|..|..||...||..|||||...    .||||.|..||||.. ||.|.||..|||||.|||...||
FDFLKVLGKGSFGKVFLVKKKDTQKWYYAMKVLKKDYIIQKNQVEHTKTERNILQHCN---HPFIVNLHYSFQTQDKLYFVMDYCNGGELFYHLQRKRRF

SEDRAKFYIAELVLALEHLHDNDIVYRD-LKPENILLDANGNIALCDFGLSKAD-LKD--RTNTFCGTTEYLAPELLLDETGYTKMVDFWS-LGVLIFEM
|||||.||.||..||.|||| ..|.||| |||||||.|..|.|.|.||||.| . .||  .|.||||| |||||| |.. .|.||.||.|. ||....||
SEDRARFYCAEIILAIEHLHSKNIIYRDYLKPENILMDKDGHICLTDFGLCKENIIKDHDKTKTFCGTPEYLAPEILNG-NGHTKAVDWWGSLGCVMYEM

CCGWSPFFAENNQKMYQKIAFGKVKFPR-DVLSQEGRSFVKGLLNRNPKHRLG-AIDDGRELRAHPFF
.||. ||.......|..||  ..||||. |..|.| .....||||..||.||| ...| .|...||.|
MCGRPPFYNQDHHQMFKKIKNQPVKFPDKDWISPECKDLISGLLNKDPKKRLGGGPNDAQEIKRHPWF
Kinase SCH9.AA AGC 412-671 36 1.6e-188 492.79 In-house 1-395 (395) Show / Hide 
Range on Protein: 412-671
Range on HMM: 1-395/395
Sequence Identity: 36% (144 aa)

FEVLRLLGKGTFGQVYQVKKK------DTQRIYAMKVLSKKV-IVKKN--EIAHTIGE------------RNILVTTASKS-------SPFIVG-LKFSF
||.|...|||.||.||.|.||      ||...||||||.||. ||.|.  ...||. |            ||||..  ..        .||||  |..||
FEFLKVIGKGSFGKVYLVRKKDGCHKKDTGKYYAMKVLKKKHKIVIKKKNMVEHTMTEHWKQDQGYVWEERNILEKCNHTHNHPIKSHHPFIVKILHYSF

QTPTD--LYLVTDYMS---------GG-ELFWHLQ---KEGRFSEDRAKFYIAE-------LVLALEHLHD-NDIVYRD-LKPENILLDANGNIALCDFG
|...   ||.| .||.         || |||.|||   |||||.|.||.||.||       .|||||.||. ..|..|| |||||||||..|.| |.|||
QDKDHTYLYFVMEYMPRYVNDLYCGGGCELFLHLQGRRKEGRFDEERARFYAAEMQKICGCIVLALEYLHSHMGIIHRDYLKPENILLDEDGHIKLTDFG

LSKADLK----------------------------------------------------DRTNTFCG--TTEYLAPELLLDETGYTKMVDFWS--LGVLI
|.|   .                                                    |||.||||  | ||.||| |     |.| .| ||  ||.|.
LCKEGMNDGEKGQQSQSNMKFHWHNKKYQKSNMDTNKCNPNNWQRNNMSQEDDTTRKKRDRTWTFCGPCTPEYMAPEIL-----YGKACDWWSFGLGCLM

FEMCCGWSPFFAENNQ----------KMYQKIA------FGKVKFPR---------DVLSQEGRSFVKGLLNRNPKHRLGAIDDG------RELRAHPFF
.|| .|..||...|.|          .|.|||       . |||||.         . .|.| ....|.||...|..|||. ...       |...||.|
YEMLTGYPPFYGDNPQENRHPFRNPMEMFQKIMNGRYFINWKVKFPFPEDPQFPEDRWFSPEAKDLIKKLLCKDPEKRLGCGGNDFGDKGAEEIKNHPWF
Kinase SCH9.AA SGK 412-671 46 8.4e-145 450.37 In-house 1-283 (283) Show / Hide 
Range on Protein: 412-671
Range on HMM: 1-283/283
Sequence Identity: 46% (133 aa)

FEVLRLLGKGTFGQVYQVKKKDT------------------QRIYAMKVLSKKVIV-------KKNEIAHTIGER-NILVTTASKSSPFIVGLKFSFQTP
|. | ..||| || |||||.||.                  . .||||||.|. |.       ||.|  |.  || .||.     ..||||.|...|||.
FDFLKVIGKGSFGKVYQVKHKDDETCQRVWLIFQSLLSQSEDKFYAMKVLQKQHIINEYRQDLKKKEQKHIMAERNVILKNM---KHPFIVNLHYAFQTK

TDLYLVTDYMSGGELFWHLQKEGRFSEDRAKFYIAELVLALEHLHDNDIVYRDLKPENILLDANGNIALCDFGLSKADLK--DRTNTFCGTTEYLAPELL
. ||.| ||. |||.| |||.|..|.||||.|| ||.|.|||.||. ||.||||||||||||. |.. |.||||.| . |  | | ||||| |||||| |
WKLYFVMDYVNGGEMFYHLQREKHFPEDRARFYAAEIVCALEYLHSQDIIYRDLKPENILLDHQGHCCLTDFGLCKEGIKTNDTTFTFCGTPEYLAPEVL

LDETGYTKMVDFWSLGVLIFEMCCGWSPFFAENNQKMYQKIAFGKVKFPRDVLSQEGRSFVKGLLNRNPKHRLGAIDDGRELRAHPFF
. .. . . || |.|| . .||  |  ||.  | | ||..|  .. ..|. . | . ..  .|||...|| |||. .|..| . ||||
RKQP-HDRTVDWWCLGCVLYEMMYGLPPFYSRNKQQMYDNIINQPLQIPPQM-SNDAWDLIQGLLQKDPKKRLGTKRDFMEIKNHPFF
Kinase SCH9.AA AktR 412-671 45 1.8e-125 423.17 In-house 1-268 (268) Show / Hide 
Range on Protein: 412-671
Range on HMM: 1-268/268
Sequence Identity: 45% (122 aa)

FEVLRLLGKGTFGQVYQVKKK-DTQRIYAMKVLSKKVIVKKNEIAHTIGERNILVTTASKSSPFIVGLKFSFQTPTDLYLVTDYMSGGELFWHLQKEGRF
|.|...||||.||.|| |.|| |.|..||||...|| |...| . ||| ||||.   . .. |||| |...||| . |... .|. ||||| ||.|...|
FHVYKCLGKGAFGKVYLVQKKRDNQKQYAMKMIKKKKIIERNQMHHTITERNIM--EMCCNHPFIVKLHYCFQTKEKLFFIMEYCPGGELFQHLKKKKKF

SEDRAKFYIAELVLALEHLHDN-DIVYRDLKPENILLDANGNIALCDFGLSK--ADL--KDRTNTFCGTTEYLAPELLLDETGYTKMVDFWSLGVLIFEM
||..|.||.|. .||||.||.. .|.|||||||||||| .|.. . ||||||   .    .....|||| ||.||| .. . |..|.||.|..|..|.||
SEEQARFYFAQILLALEYLHQHMNIIYRDLKPENILLDEDGHVKITDFGLSKLQFMMHYDEKAYSFCGTPEYMAPEMITKKKGHNKSVDWWAFGIFIYEM

CCGWSPFFAENNQKMYQKIAFGK-VKFPR-DVLSQEGRSFVK-GLLNRNPKHRLG-AIDDGRELRAHPFF
  |  ||...|.. |.||| .   .|||    .|.. ..... .||..||..||| .  .  |.. ||.|
VTGCPPFYHKNQNQMFQKIKIKQQNKFPYPSYFSSQCKDLIQRKLLCKNPNKRLGYYCNGWEEIKSHPWF
Kinase SCH9.AA RSK 415-671 45 1.1e-119 403.89 In-house 1-278 (278) Show / Hide 
Range on Protein: 415-671
Range on HMM: 1-278/278
Sequence Identity: 45% (127 aa)

LRLLGKGTFGQVYQVKKK---DTQRIYAMKVLSKKVIVKKNE-IAHTIGERNILVTTASKSSPFIVGLKFSFQTPTDLYLVTDYMSGGELFWHLQKEGR-
|..||.| .| |....|.   ||..|||||||.|..||...  ..||  ||||| ..  ...|||| |. .|||.. |||...|..||||| |||||.. 
LKVLGQGGYGKVFLCRKCTHHDTGQIYAMKVLKKAKIVQRQKDTRHTMTERNILERC--QQHPFIVTLHYAFQTEGKLYLIMEYCRGGELFTHLQKEKHF

--FSEDRAKFYIAELVLALEHLHDNDIVYRDLKPENILLDA---NGNIALCDFGLSKA-DLK--DRTNTFCGTTEYLAPELLL---DETGYTKMVDFWSL
  ||||.|.||.||.|||.||||. .|..|||||||||.|    .| | |.|||..|  ...   .|.|||.| ||.|||.|     . |..| .| |||
GCFSEDEACFYMAEIVLAVEHLHQQGIIHRDLKPENILYDDESNEGHIKLTDFGFCKQFRCDHNQWTMTFCYTIEYMAPEMLKRANQQGGHDKACDWWSL

GVLIFEMCCGWSPFFA---ENNQKMYQKIAFGK--VKFP-RDVLSQEGRSFVKGLLNRNPKHRLGA-IDDGRELRAHPFF
|||..||  | .|| .   .| ..  ..|  ||  ...|  . |||| .......| |.|. |||.  .|  |...||.|
GVLMYEMLTGCPPFQGPNDNNRKEIMKRIQKGKFSLTMPNWQYLSQEAKDLIRKMLHRDPHKRLGCGPQDAEEIKQHPWF
Kinase SCH9.AA RSK-Unclassified 412-671 43 1.7e-116 367.57 In-house 1-283 (283) Show / Hide 
Range on Protein: 412-671
Range on HMM: 1-283/283
Sequence Identity: 43% (125 aa)

FEVLRLLGKGTFGQVYQVKKKDTQRIYAMKVLSKKVIVKKNEIAHTIGERNILVTTASKSSPFIVGLKFSFQTPTDLYLVTDYMSGGELFWHLQ--KEGR
|.. ||.|.| ||.|| |.|||||.|||||||.|. ....| |   . |.||. ||     |||| | .||||   |||. .|  ||..| |||  || .
FIKHRLIGQGDFGKVYLVRKKDTQQIYAMKVLHKHKMIRHNKIKYVMTEQNIMATTN---HPFIVTLYHSFQTQDYLYLCMEYCMGGDFFRHLQTRKEKC

FSEDRAKFYIAELVLALEHLHDNDIVYRDLKPENILLDANGNIALCDFGLSKAD-------LK----------------DRTNTFCGTTEYLAPELLLDE
|.||...||..| ..|||.||  |..||||||.||.|.  | . | ||.||.         .|                 ||| |||| ||||||..   
FCEDDVRFYASEVTAALEYLHKRDFIYRDLKPDNIVLHQEGHVMLTDFDLSIQAKDSKKPVMKGSAQSTYVDTKICDHGFRTNSFCGTEEYLAPEMIR-R

TGYTKMVDFWSLGVLIFEMCCGWSPFFAENNQKMYQKIAFGKVKFP-RDVLSQEGRSFVKGLLNRNPKHRLGAIDD-GRELRAHPFF
 | || || | ||....||  |  |. ..|   ... |  ..||||    .|.. |. .| ||.|||  |||.      . ..||||
CGHTKAVDWWTLGIVMYEMLFGCPPYYGNNKNETFYNIEKNHVKFPHDSYISNNCRDLIKKLLQRNPAKRLGCKMGDADDIKRHPFF
Kinase SCH9.AA PKA 412-671 43 3.1e-115 389.13 In-house 1-263 (263) Show / Hide 
Range on Protein: 412-671
Range on HMM: 1-263/263
Sequence Identity: 43% (117 aa)

FEVLRLLGKGTFGQVYQVKKKDTQRIYAMKVLSKKVIVKKNEIAHTIGERNILVTTASKSSPFIVG-LKFSFQTPTDLYLVTDYMSGGELFWHLQKEGRF
|| ...||.|.|| |.....|.. ..||||.|.|  ||. . . |.. |.|||  .   ..||||  ....||... ||.| .| .|||.| .|.|.|||
FEIIQTLGTGSFGRVMLCRHKHSGNYYAMKMLKKQEIVRLKQVEHVHNEKNILQNI---KHPFIVKKMYWTFQDDRYLYMVMEYVPGGEMFSYLRKSGRF

SEDRAKFYIA-ELVLALEHLHDNDIVYRDLKPENILLDANGNIALCDFGLSKADLKDRTNTFCGTTEYLAPELLLDETGYTKMVDFWSLGVLIFEMCCGW
|.. ||||.| . ||||| ||  .|.||||||||||.| ||.| . ||| .|  ..||| | ||| |||||| .. . |. | || |.||.||.||  | 
SNPHAKFYAASQIVLALEYLHSQNIIYRDLKPENILIDKNGHIKITDFGFAKK-VDDRTWTLCGTPEYLAPEIIQSKNGHGKSVDWWALGILIYEMLAGY

SPFFAE--NNQKMYQKIAFGKVKFPRDVLSQE--GRSFVKGLLNRNPKHRLGAID-DGRELRAHPFF
.||...  .  ..|.||. ||.|||| . |..   ....| ||..... |.|  . ...  . |..|
PPFYDHNRDPMQIYEKICNGKIKFPRHFDSDANYFKDLIKKLLQVDLTKRYGNMKNGVNDIKNHKWF
Kinase SCH9.AA S_TKc 412-671 37 2.5e-108 367.09 SMART 1-231 (231) Show / Hide 
Range on Protein: 412-671
Range on HMM: 1-231/231
Sequence Identity: 37% (101 aa)

FEVLRLLGKGTFGQVYQVKKKDTQRIYAMKVLSKKVIVKKNEIAHTIGERNILVTTASKSSPFIVGLKFSFQTPTDLYLVTDYMSG--GELFWHLQKEGR
.|.||..|||.||.||....|.|.||.|.|...           |.. |..||        |.|| |. .||. ..||.|..|..|  |.||....| ||
YEILRKIGKGAFGKVYKCRHKKTGRIVAIKIIK----------EHIRREIQILKK----HHPNIVKLYDVFQD-DHLYMVMEYCDGDLGDLFDYIKKRGR

------FSEDRAKFYIAELVLALEHLHDNDIVYRDLKPENILLDANGNIALCDFGLSKADLKDRTNTFCGTTEYLAPELLLDETGYTK-MVDFWSLGVLI
      |.| .|.||......|||..|.. |..|||||||||||   .| .|||||..       .||||| .|.|||.|    ||.|  .| ||.|...
HGLRFPFPE-HARFYMYQICCALEYCHSHGIIHRDLKPENILLDE--HIKICDFGLARQL-----TTFCGTPWYMAPEVL----GYGKCKCDWWSCGCIL

FEMCCGWSPFFAENNQKMYQKIAFGKVKFPRDVLSQEGRSFVKGLLNRNPKHRLGAIDDGR---ELRAHPFF
.||.||  ||   . |.|..||            |.|...|....|...|..|..| .  .   . ..||.|
YEMLCGYPPFP--QMQMMFKKIG-----------SPEAKDFIRKCLQKDPEKRPTA-EALQDEWDIKCHPWF
Kinase SCH9.AA p70 412-671 41 5.70000000001e-103 348.4 In-house 1-299 (299) Show / Hide 
Range on Protein: 412-671
Range on HMM: 1-299/299
Sequence Identity: 41% (126 aa)

FEVLRLLGKGTFGQVYQVKKKD---TQRIYAMKVLSK-KVIVKKNEIAHTI-------------------------GERNILVTTASKSSPFIVGLKFSF
|| |..|||| .| |.||.|     | .||||||| | |..      |||                           ||||| .     .|||. | ..|
FELLKVLGKGGYGKVFQVRKVTGEDTGKIYAMKVLRKAKIVRNQKDTAHTREDEDKNDGNNNDNDDGLSKRLERTFAERNILEEVK---HPFICDLHYAF

QTPTDLYLVTDYMSGGELFWHLQKEGRFSEDRAKFYIAELVLALEHLHDNDIVYRDLKPENILLDANGNIALCDFGLSKADLKDRTN------------T
||   |||. .|..||||| || ..| . || |.|| .| ..||||||  .|.||||||||..|.. | . | ||||.|  ..| .             |
QTNGKLYLILEYLHGGELFMHLERHGIWMEDTACFYLSEIICALEHLHQHGIIYRDLKPENCMLNQQGHVVLTDFGLCKESIHDGAVDEEDPENVNATHT

FCGTTEYLAPELLLDETGYTKMVDFWSLGVLIFEMCCGWSPFFAENNQKMYQKIAFGK--VKFPRDVLSQEGRSFVKGLLNRNPKHRLG-AIDDGRELRA
|||| || |||.|.  .|. . || ||||.|.. |  |  || .|| .|   ||  ||  .| |   |..|.|  .| || |.|. |.|   .|  . ..
FCGTIEYMAPEILM-RCGHNHAVDWWSLGCLMYDMLTGGPPFTGENRKKTIDKILKGKQGLKLPP-YLTHEMRDLIKKLLKRHPTQRWGAGPEDAADIQE

HPFF
||||
HPFF
Kinase SCH9.AA PKC 412-671 41 2.4e-100 326.0 In-house 1-262 (262) Show / Hide 
Range on Protein: 412-671
Range on HMM: 1-262/262
Sequence Identity: 41% (111 aa)

FEVLRLLGKGTFGQVYQVKKKDTQRIYAMKVLSKKVIVKKNEIAHTIGERNILVTTASKSSPFIVGLKFSFQTPTDLYLVTDYMSGGELFWHLQKEGRFS
|. |. |||| || |  ...|.|...||.||| | ||..   .  |  |. .| . .    || ..|  .|||.  |. |  |  || | .| |. .||.
FNFLKVLGKGSFGKVMLAERKGTDEYYAIKVLKKDVIIQDDDVECTMTEKRVLALAWK--HPFLTHLHCCFQTMDRLFFVMEYVNGGDLMFHIQQQRRFK

EDRAKFYIAELVLALEHLHDNDIVYRDLKPENILLDANGNIALCDFGLSKADLK--DRTNTFCGTTEYLAPELLLDETGYTKMVDFWSLGVLIFEMCCGW
| .|.|| || ..||  ||...|.||||| .|.|||. | | . |||..|  .   |.|.||||| .|.||| |  .  |.| ||.|..||| .|| .| 
EEHARFYAAEIICALQFLHEKGIIYRDLKLDNVLLDHEGHIKIADFGMCKENMWNGDTTSTFCGTPDYIAPEILQYQE-YGKSVDWWAFGVLMYEMMAGQ

SPFFAENNQKMYQKIAFGKVKFPRDVLSQEGRSFVKGLLNRNPKHRLGAIDDG----RELRAHPFF
||| .|.   . | |   .. .||. ||.|  |  ||....||. |||.  ..    .. |.||||
SPFHGEDEDELFQSIMHDNPHYPRW-LSKEAVSICKGFMTKNPEKRLGCHPQQEEGEQDIREHPFF
Kinase SCH9.AA RSK 412-671 37 1.7e-95 323.56 In-house 1-271 (271) Show / Hide 
Range on Protein: 412-671
Range on HMM: 1-271/271
Sequence Identity: 37% (106 aa)

FEVLRLLGKGTFGQVYQVKKK---DTQRIYAMKVLSKKVIVKKNEIAHTIGERNILVTTASKSSPFIVGLKFSFQTPTDLYLVTDYMSGGELFWHLQKEG
.|... .|.|.|. || .||.   ||.. ||||.. |.... |     .  ||.||       .|||| |. .||. . .|...| | ||.|| .|.|..
YELHECIGQGSFSKVYVCKKCQHKDTNQHYAMKIIKKATRDVKDR-VCWEEERIILRYG---HHPFIVKLHYVFQDEGKVYMIMDFMRGGDLFDRLLKQK

RFSEDRAKFYIAELVLALEHLHDNDIVYRDLKPENILLDAN----GNIALCDFGLSKADLKDRTN---TFCGTTEYLAPELLLDETGYTKMVDFWSLGVL
 |||. .||| ||. ||.|.||  .||.|||||||||.|.     | | .||||..|  |.|..    |||.| .|.||| | .  |... .|.||.|||
MFSEREVKFYMAEIALAMEYLHSQGIVHRDLKPENILYDDESGNPGHIKICDFGFAKQ-LRDENGMLMTFCYTANYMAPEVLKRQ-GHDQACDWWSFGVL

IFEMCCGWSPFFAENNQKMYQKIAFGKVKFPR--------DVLSQEGRSFVKGLLNRNPKHRLGA-IDDGRELRAHPFF
 .||  |  || . ... . ..|.  ..|  .        | .|.|  . . ..| |.|  ||||  ..  . . ||.|
MYEMLTGCTPFQNKPRDTPMNIIQ--RIKLGMFSMTHGNWDFISDEAKDLLRMMLHRDPHNRLGAGPNGVEQIKQHPWF
Kinase SCH9.AA Pkinase 412-671 30 1.6e-90 311.85 Pfam 1-293 (293) Show / Hide 
Range on Protein: 412-671
Range on HMM: 1-293/293
Sequence Identity: 30% (92 aa)

FEVLRLLGKGTFGQVYQVKKKDTQRIYAMKVLSKKVIVKKNEIAHTI-GERNILVTTASKSSPFIVGLKFSFQTPTDLYLVTDYMSGG----ELFWHLQ-
....| .|.|.||.||. ..|.|..|.|.|...|. . .. ...|.   |  |.    .  .|.|| |. .|......|.|..|. ||    .|| ... 
YHIGRKIGSGSFGCVYKCHHKGTGKIVAVKIIKKRHEKSWKDQTHRRLSEIQIMKRL-N--HPNIVRLYDWFEDKDHIYMVMEYCEGGLYVMDLFDYIST

-KEGRF--SEDRAKFYIAELVLALEHLHDNDIVYRDLKPENILLDANGNI----ALCDFGLSK---ADLKDRTNTFCGTTEYLAPELLLDETGYTKMVDF
 ..|.|  ||. .|||. ... .||..|.. |..|||||||||.| ||.|     .|||||.|      .  ..||||| .|.|||.... ..|.. || 
WRHGCFYFSEWECKFYMYQILRGLEYCHSMGIIHRDLKPENILIDNNGHIDACVKICDFGLAKQFDY-NNS-MTTFCGTPWYMAPEVIRGGQYYGPKVDM

WSLGVLIFEMCCGWSPFFAE------NNQKMYQKIAFGKVKFPRDVLS--------------------QEGRSFVKGLLNRNPKHRLGAIDDGRELRAHP
||.|....||.||  ||  .      . ..|...|  ....|... ..                    .|...|.|..|...|| |..     ...  ||
WSCGCILYEMLCGRPPFPGHCWHDNHDQMQMICRIMGPPLHFDWPWWCSISYFFFRHWHFHWTFHNWSEECKDFIKWCLCKDPKKRPT----AEQILQHP

FF
.|
WF
Kinase SCH9.AA S_TK_X 672-740 37 2.8e-25 91.2 SMART 1-79 (79) Show / Hide 
Range on Protein: 672-740
Range on HMM: 1-79/79
Sequence Identity: 37% (32 aa)

ADIDWEALKQ--KKIPPPFKPHLV----SETDTSNFDPEFTTASTSYMNKHQPMMTATPLSPAMQAK----------FAGFTFVD
..|||..| .  |.|.||||| .     |.||||||||||| .. .       ... .|||..|...          |.|||.| 
RGIDWDKLYNQQKEIEPPFKPKIKEVYASPTDTSNFDPEFTEETPM------LTPDDPPLSNSMWQNEMETEIPPDPFRGFTYVF
Kinase SCH9.AA Pkinase_C 691-742 36 4.5e-13 49.25 Pfam 1-46 (46) Show / Hide 
Range on Protein: 691-742
Range on HMM: 1-46/46
Sequence Identity: 36% (19 aa)

HLVSETDTSNFDPEFTTASTSYMNKHQPMMTATPLSPAMQAKFAGFTFVDES
.. |.||||||||||| .. ..       .. . .|...|. | |||.| ..
QVKSPTDTSNFDPEFTDEPPMDTP-----PDWR-MSSGDQEPFRGFTYVNPD
Kinase SCH9.AA TyrKc 412-665 19 4.8e-11 -44.05 SMART 1-280 (280) Show / Hide 
Range on Protein: 412-665
Range on HMM: 1-280/280
Sequence Identity: 19% (59 aa)

FEVLRLLGKGTFGQVYQVKKKDTQRIYAMKVLSKKVIVKKNEIAHTIGERNIL----VTTAS-KSSPFIVGLKFSFQTP-------TDLYLVTDYMSGGE
 . .. || | ||.||. . |             .| ||.    .   .. ..    . .   .. | || |     ..         |..|. ||..| 
ITLGKKLGEGAFGEVYKGTWK------------IQVAVKMLKEDA---REDFMREARIMCKLGGHHPNIVRLYGVCTQQGRNFMYIEPLMIVMEYMPHGD

LFWHLQKEGR-FSEDRAKFYIAELVLALEHLHDNDIVYRDLKPENILLDANGNIALCDFGLSKADLKD-------RTNTF----CGTT----EYLAPELL
|  .|.| .. .. .    .        |.||.. .. |||   |.|...|. .  .|||||..   |        . .     .| |      .||| .
LKDYLRKHRPKLCMKDLLSFCWQIACGMEYLHSKNCIHRDLAARNCLVGENHTVKISDFGLSRDIYDDDQQGESKDYYRKKEHKGGKTMLPIRWMAPECI

LDETGYTKMVDFWSLGVLIFEMC-CGWSPFFA-----ENNQKMYQKIAFGKVKFPRDV--------LSQEGRSFVKGLLNRNPKHRLGAIDDGREL
 ..  .|   | || ||...|..  | .|         .|| .....  |.   . .          ..|  .  |   ...|. |    .  ...
-NYGKFTTKSDVWSFGVCMWEIFTYGQQPYPGMIQQMMSNQEVIEYVKQGYRMPQPPNDYPMSFVCCPDEMYQIMKQCWHEDPEDRPTFSEIHECF