Gene SKM1 (Bakers Yeast)

SKM1

Species: Bakers Yeast
Alias: SKM1
External Links: Saccharomyces Genome Database Link ,
Annotation:

Classification

Group: STE
Family: STE20
Subfamily: PAKA

Sequence

Name Sequence Type Origin Length Description Download
SKM1.kin_dom Protein Kinase Domain Sugen global kinase HMM prediction 280 Kinase domain by global Sugen HMM Fasta, JSON
SKM1.AA Protein Refseq_NP 655 Serine/threonine protein kinase with similarity to Ste20p and Cla4p; Skm1p [Saccharomyces cerevisiae] Fasta, JSON

Protein domain

Protein domains of SKM1.AA. The domains are annotated by HMM profiles from Pfam and SMART, as well as in-house data which includes HMMs of each individual kinase group, family and subfamily. Here is domain list in details, including sequence identity, significance and alignment. In particular, you can find can find the best hit kinase group/family/subfamily, which is helpful to understand the relationship between kinases.Kinase domain and best hit kinase group/family/subfamily are highlighted in red and blue. Visualized by pviz.

Usage: Zoom in selected region by dragging mouse and zoom out by double-clicking.

Show/hide domain list
Domain Protein name Domain Name Range Identity (%) Significance Score Profile Source Profile Range (length) Alignment
PH SKM1.AA PH 4-118 25 1.9e-18 69.18 Pfam 1-92 (92) Show / Hide 
Range on Protein: 4-118
Range on HMM: 1-92/92
Sequence Identity: 25% (30 aa)

VKKEGWISYKVDGLFSFLWQKRYLVLNDSYLAFYKSDKCNEEPVLSVPLTSITNVSRIQL--KQNCFEILRATDQKENISPINSYFYESNSKRSIFISTR
|.||||.. |.   ..  |.||..|| ...| .||.||  ..|  |.|| .. .| ..    ...||.|   .                   |...... 
VIKEGWLHKKG---KRKSWKKRWFVLFNNCLYYYKDDK--YRPKGSIPLSDC-QVTKVPDNKRPHCFQIRT-DR------------------RTYYFQAE

TERDLHGWLDAIFAKCP
.| ... |..|| . | 
SEEEMNDWMQAIQSACR
PH SKM1.AA PH 4-120 23 2.7e-16 61.37 SMART 1-82 (82) Show / Hide 
Range on Protein: 4-120
Range on HMM: 1-82/82
Sequence Identity: 23% (27 aa)

VKKEGWISYKVDGLFSFLWQKRYLVLNDSYLAFYKSDKCNEEPVLSVPLTSITNVSRIQLKQNCFEILRATDQKENISPINSYFYESNSKRSIFISTRTE
| ||||.. |     .  |.||..|| ...| .||..    .|  |.||...  |..      ||||   .                    ........|
VIKEGWLYKKS----K-RWKKRWFVLFNDCLYYYKDK----KPKGSIPLSDC-TVRE-P----CFEIHH-DR-------------------TYYFQCESE

RDLHGWLDAIFAKCPLL
 ... |..|| . .  .
EEMQEWMQAIQKAIHNN
PBD SKM1.AA PBD 122-180 45 4.7e-27 96.8 Pfam 1-60 (60) Show / Hide 
Range on Protein: 122-180
Range on HMM: 1-60/60
Sequence Identity: 45% (27 aa)

GVSSP-TNFTHKVHVGFDPKVGNFVGVPDSWAKLLQTSEITYDDWNRNSKAVIKALQFYE
..|.| |||.|..|||.|.. |.|.| |..|.||||.|.|. .....|..||....|||.
MISTPLTNFKHTMHVGWDGQTGFFTGMPPEWQKLLQSSGISKPEQKHNPQAVFDVVQFYQ
PBD SKM1.AA PBD 123-158 47 9.6e-15 56.22 SMART 1-38 (38) Show / Hide 
Range on Protein: 123-158
Range on HMM: 1-38/38
Sequence Identity: 47% (18 aa)

VSSPT-NFTHKVHVG-FDPKVGNFVGVPDSWAKLLQTS
.|.|| ||.|.|||| .|.. |.|.| | .|..||...
ISTPTGNFKHIVHVGPWDGQTGEFTGLPHQWQHLLKHC
Kinase SKM1.AA PAKA 360-639 54 6.8e-183 613.9 In-house 1-260 (260) Show / Hide 
Range on Protein: 360-639
Range on HMM: 1-260/260
Sequence Identity: 54% (153 aa)

FQLVEKAGQGASGAVYLSKRIKLPQE-NDPRFLKSHCHRVVGERVAIKQIRLSEQPKKQLIMNELLVMNDSRQENIVNFLEAYIIDDEELWVIMEYMEGG
.. .||.||||||.||....|| .|| |                |||||.....||||.||.||.|||......||||....|.. |.||||.|||||||
YKFMEKIGQGASGEVYVATNIKTNQEEN----------------VAIKQMNMKNQPKKELIINEILVMKECKHKNIVNYIDSYLV-DDELWVVMEYMEGG

CLTDILDAVARSNTGEHSSPLNENQMAYIVKETCQGLKFLHNKKIIHRDIKSDNILLNSQGLVKITDFGFCVELTEKRSKRATMVGTPYWMAPEIVNQKG
||||...........    ...|.|.||...|..|||.|.|.|..||||||||||||...| |||||||||..||....||.||||||||||||....| 
CLTDVITQCCNIQCN----YMDEGQIAYVCRECLQGLEFIHSKHRIHRDIKSDNILLGMDGSVKITDFGFCAQLTQEQQKRNTMVGTPYWMAPEVIRRKQ

YDEKVDVWSLGIMLIEMIEGEPPYLNEDPLKALYLIANNGSPKLRHPESVSKQTKQFLDACLQVNVESRASVRKLLTFEFL
||||||.||||||.|||||||||||||.||.|.||||.|| |....|...|.....|||.||.|.|..|||...||...||
YDEKVDIWSLGIMAIEMIEGEPPYLNEPPLRAMYLIATNGKPDIKDPDKWSQEFCDFLDKCLCVDVDRRASAQELLHHPFL
Kinase SKM1.AA STE20 360-639 40 2.3e-142 479.24 In-house 1-288 (288) Show / Hide 
Range on Protein: 360-639
Range on HMM: 1-288/288
Sequence Identity: 40% (123 aa)

FQLVEKAGQGASGAVYLSKRIKLPQE-NDPRFLKSHCHRVVGERVAIKQIRLSEQ----PKKQLIMNELLVMNDSRQENIVNFLEAYIID---DEELWVI
..|.|| |||..|.||.   ..  .. |              .|||||.. |...    .....|..| ..|.... .|||.....|. |   |.|||..
YELLEKIGQGSYGKVYKAYHKPTGEYCN--------------QRVAIKKMNLEKCDNEQDEWEDIQKEISIMKQCKHPNIVKYYGSYLKDDTCDDELWIV

MEYMEGGCLTDILDAVARSNTGEHSS-PLNENQMAYIVKETCQGLKFLHNKKIIHRDIKSDNILLNSQGLVKITDFGFCVELTE-----KRSKRATMVGT
|||..||.||||.... . .   |.  |.|| | ||| .|..|||..||...|||||||.|||||...| ||..|||.|  ||.     ...|| |.|||
MEYCGGGSLTDIMKHCMKCGKN-HKGHPMNEEQIAYICREVLQGLDYLHSNHIIHRDIKADNILLTEDGEVKLADFGVCAQLTKHGRDTMQFKRNTFVGT

PYWMAPEIVNQ-----KGYDEKVDVWSLGIMLIEMIEGEPPYLNEDPLKALYLIA--NNGSPKLRH--PESVSKQTKQFLDACLQVNVESRASVRKLLTF
|||||||....     ||||.|.|.|||||..|||.||||||... |..|...|.  .|..|.|..  |.. |.. ..|.| |||...| |... .||. 
PYWMAPEVIQCMEGPDKGYDYKCDIWSLGITAIEMAEGEPPYFDMHPMRAMFMIPKNQNPPPTLKDDKPHKWSPEFHDFVDKCLQKDPEKRPTASQLLKH

EFL
.|.
PFI
Kinase SKM1.AA STE 360-639 30 2.8e-117 395.93 In-house 1-359 (359) Show / Hide 
Range on Protein: 360-639
Range on HMM: 1-359/359
Sequence Identity: 30% (113 aa)

FQLVEKAGQGASGAVYLSKRI------KLPQE-NDPRFLKSHCHRVVGERVAIKQIRLSEQ-----------------PKKQLIMNELLVMNDSR--QEN
....|| |.||.| ||. ...      |  .. |             ||..||||..|...                  ..| |..|. .|....   .|
WEGIEKIGKGAFGTVYKAMNHKNCNIHKTGEVEN---------NGETGEIMAIKQMNLENCNNKDENQENQELENKNHEEMQQILKEIKIMKKCNHMHPN

IVNFLEAYIID------DEELWVIMEYMEGGCLTDILDAV-ARSNTGEHS----SPLNENQMAYIVKETCQG-LKFLHNKKIIHRDIKSDNILLNSQGLV
||... .|. .      |.|||..||||.||.|.||.. .  . ..  |.    ....|.| |||......| |..||...|||||||..||||     |
IVKYYGCYFKEGHNHKNDDELWICMEYMDGGSLDDIIKHKYGCGKPLNHNRQHQHRFPESQIAYICRQILKGLLYYLHSHHIIHRDIKPANILL-----V

KITDFGFCVELTEK----------------RSKRATMVGTPYWMAPEIVNQ------KGYDEKVDVWSLGIMLIEMIEGEPPYLNEDPLKALYLIANN--
|..|||.|  ||..                 .|| |.|||| |||||...|      ||||.|.|.||||...|||..|.||. .. |..|...|..|  
KLCDFGVCGQLTDSMANIQSNNIIDCIETMQQKRNTFVGTP-WMAPEVIQQNGQGRDKGYDTKCDIWSLGCTIIEMATGKPPWHDMHPMRAMFMIPFNYH

-------------GSPKLRH-----------------PESVSKQTKQFLDACLQVNVESRASVRKLLT--FEFL
             ..|.| .                 |...|.  |.|.. ||| . . |... .||    .|.
MQQQFEQLCIVNGPPPPLPDHLSQNEMISYGGSGTTYPHKWSPEFKDFINKCLQKDPNKRPTASQLLKSEHPFI
Kinase SKM1.AA PAKB 400-639 44 5.5e-89 301.95 In-house 24-252 (252) Show / Hide 
Range on Protein: 400-639
Range on HMM: 24-252/252
Sequence Identity: 44% (106 aa)

GERVAIKQIRLSEQPKKQLIMNELLVMNDSRQENIVNFLEAYIIDDEELWVIMEYMEGGCLTDILDAVARSNTGEHSSPLNENQMAYIVKETCQGLKFLH
|  ||.|.  |  |    |  ||  .| | . .|||.. . | ..| ||||.||.|||| ||||  .. |         .|| | |.. .   | | .||
GRQVAVKKMDLRKQQRRELLFNEVVIMRDYQHPNIVEMYSSYLVGD-ELWVVMEFMEGGALTDIVTHT-R---------MNEEQIATVCRQVLQALAYLH

NKKIIHRDIKSDNILLNSQGLVKITDFGFCVELTEKRSKRATMVGTPYWMAPEIVNQKGYDEKVDVWSLGIMLIEMIEGEPPYLNEDPLKALYLIANNGS
....|||||||| ||| . | || .|||||  . .   ||  .||||||||||..    |. .||.||||||.|||..||||| || ||.|.  |  .  
AQGVIHRDIKSDSILLTHDGRVKLSDFGFCAQVSKEVPKRKSLVGTPYWMAPEVISRLPYGTEVDIWSLGIMVIEMVDGEPPYFNEPPLQAMKRIRDMHP

PKLRHPESVSKQTKQFLDACLQVNVESRASVRKLLTFEFL
|.|.    || . ..||| .|  ... |..   ||   ||
PRLKNHHKVSPRLREFLDRMLVRDPNQRWTAQELLRHPFL
Kinase SKM1.AA S_TKc 360-639 27 2.8e-83 283.91 SMART 1-231 (231) Show / Hide 
Range on Protein: 360-639
Range on HMM: 1-231/231
Sequence Identity: 27% (80 aa)

FQLVEKAGQGASGAVYLSKRIKLPQENDPRFLKSHCHRVVGERVAIKQIRLSEQPKKQLIMNELLVMNDSRQENIVNFLEAYIIDDEELWVIMEYMEG--
.....| |.|| | ||. . .|                  |..||||.|.       . |..|. ..   . .|||......    ..|...|||..|  
YEILRKIGKGAFGKVYKCRHKK-----------------TGRIVAIKIIK-------EHIRREIQILKK-HHPNIVKLYDVFQD--DHLYMVMEYCDGDL

GCLTDILDAVARSNTGEHSSPLNENQMAYIVKETCQGLKFLHNKKIIHRDIKSDNILLNSQGLVKITDFGFCVELTEKRSKRATMVGTPYWMAPEIVNQK
| | |...   |  ..   .|..| . .......|..|...|...|||||.| .||||..   .||.|||.. .|        |..|||..||||..   
GDLFDYIKKRGRHGLR---FPFPE-HARFYMYQICCALEYCHSHGIIHRDLKPENILLDE--HIKICDFGLARQL-------TTFCGTPWYMAPEVL---

GYDE-KVDVWSLGIMLIEMIEGEPPYLNEDPLKALYLIANNGSPKLRHPESVSKQTKQFLDACLQVNVESRASVRKLLT-------FEFL
||.  |.|.||.|..|.||. |.||.   .. . . .|              |.. |.|.. |||.. | | .. ..|.        ...
GYGKCKCDWWSCGCILYEMLCGYPPFP--QMQMMFKKIG-------------SPEAKDFIRKCLQKDPEKRPTA-EALQDEWDIKCHPWF
Kinase SKM1.AA Pkinase 360-639 22 2.5e-79 274.66 Pfam 1-293 (293) Show / Hide 
Range on Protein: 360-639
Range on HMM: 1-293/293
Sequence Identity: 22% (73 aa)

FQLVEKAGQGASGAVYLSKRIKLPQENDPRFLKSHCHRVVGERVAIKQIRLSEQPKKQLIMN----ELLVMNDSRQENIVNFLEAYIIDDEELWVIMEYM
.....| |.|..| ||. .... ..                 .||.|.|..... ..... .    |. .|.  . .||| .....   . .....|||.
YHIGRKIGSGSFGCVYKCHHKGTGK-----------------IVAVKIIKKRHEKSWKDQTHRRLSEIQIMKRLNHPNIVRLYDWFED-KDHIYMVMEYC

EGG----CLTDILDAVARSNTGEHSSPL--NENQMAYIVKETCQGLKFLHNKKIIHRDIKSDNILLNSQGLV----KITDFGFCVEL-TEKRSKRATMVG
|||     | |.. .       . . ..   |..   .......||...|...|||||.|..|||....| .    ||.|||..  . . . |   | .|
EGGLYVMDLFDYIST-------WRHGCFYFSEWECKFYMYQILRGLEYCHSMGIIHRDLKPENILIDNNGHIDACVKICDFGLAKQFDY-NNS-MTTFCG

TPYWMAPEIVN-QKGYDEKVDVWSLGIMLIEMIEGEPPYLNE----DPLKALYLIANNGSPKLRHPESVS---------------------KQTKQFLDA
||..||||... ...|. |||.||.|..|.||. |.||. ..    . .  ...|.....|.|. ... .                     .  |.|.. 
TPWYMAPEVIRGGQYYGPKVDMWSCGCILYEMLCGRPPFPGHCWHDN-HDQMQMICRIMGPPLHFDWPWWCSISYFFFRHWHFHWTFHNWSEECKDFIKW

CLQVNVESRASVRKLLTFEFL
||... ..| . . .|  ...
CLCKDPKKRPTAEQILQHPWF
Kinase SKM1.AA YSK 445-639 42 8.9e-78 233.68 In-house 69-257 (257) Show / Hide 
Range on Protein: 445-639
Range on HMM: 69-257/257
Sequence Identity: 42% (85 aa)

DEELWVIMEYMEGGCLTDILDA--VARSNTGEHSSPLNENQMAYIVKETCQGLKFLHNKKIIHRDIKSDNILLNSQGLVKITDFGFCVELTEKRSKRATM
|  ||.||||  || . | . .  |          .. | . | | .|  .||..||  . ||||||. |.||. .| ||. |||    .|.   || |.
DTKLWIIMEYCGGGSCLDLMKPKYV---------GQFDEKYIAIILREILKGLDYLHSERKIHRDIKAANVLLSEHGDVKLCDFGVAGQITDTQIKRNTF

VGTPYWMAPEIVNQ--KGYDEKVDVWSLGIMLIEMIEGEPPYLNEDPLKALYLIANNGSPKLRHPESVSKQTKQFLDACLQVNVESRASVRKLLTFEFL
||||||||||.. |   .||.|.|.|||||  .||  |||||   .|.... ||  |  |||   .| ||  | | ..||  . | | |   || ..| 
VGTPYWMAPEVICQEVSYYDFKADIWSLGITAYEMAKGEPPYCDYHPMRVMFLIPKNNPPKLEG-RSYSKMFKEFVECCLNKDPEQRPSAKELLKHKFI
Kinase SKM1.AA MST 419-639 40 1.7e-70 223.23 In-house 41-254 (254) Show / Hide 
Range on Protein: 419-639
Range on HMM: 41-254/254
Sequence Identity: 40% (91 aa)

IMNELLVMNDSRQENIVNFLEAYI-IDDEELWVIMEYMEGGCLTDILDAVARSNTGEHSSPLNENQMAYIVKETCQGLKFLHNKKIIHRDIKSDNILLNS
| .|   | .   ..|| .   |.   ....| .||| ..| . ||  .  |        .||| | | | . | |||. ||. |.||||||. ||||| 
IIKEISIMQQCKSKYIVKYYGSYFDAKNNHCWIVMEYCGMGSVCDIMKITQR--------TLNEQQIACILYDTLQGLQYLHDNKKIHRDIKAGNILLNH

QGLVKITDFGFCVELTEKRSKRATMVGTPYWMAPEIVNQKGYDEKVDVWSLGIMLIEMIEGEPPYLNEDPLKALYLIANNGSPKLRHPESVSKQTKQFLD
 |  |  |||   .||.   || | .|||||||||  .. .|| |.| |||||  ||| ||.||| .  |  |. .|  . .|... ||  | .   |. 
EGECKLADFGVSGQLTDTMAKRNTVIGTPYWMAPEVIQEIKYDCKADIWSLGITAIEMAEGMPPYSDIHPMRAMFMIPQKPPPTFKDPEQWSQEFNDFVC

ACLQVNVESRASVRKLLTFEFL
 ||| | | |..   ||  .| 
KCLQKNPEQRWTAEQLLQHPFI
Kinase SKM1.AA KHS 360-639 36 4.9e-63 210.83 In-house 1-258 (258) Show / Hide 
Range on Protein: 360-639
Range on HMM: 1-258/258
Sequence Identity: 36% (103 aa)

FQLVEKAGQGASGAVYLSKRIKLPQENDPRFLKSHCHRVVGERVAIKQIRLSEQPKKQLIMNELLVMNDSRQENIVNFLEAYIIDDEELWVIMEYMEGGC
..|. . | |  | ||  ..|                 . .| .|.| |..  .   ..|  |...| | |  ||| .  .|.  |  ||..|||  || 
YELLQRVGSGTYGDVYKARDI-----------------QSDELAAVKVIKMEPGDDFAVIQQEIMMMKDCRHPNIVAYFGSYLRRD-KLWICMEYCGGGS

LTDILDAVARSNTGEHSSPLNENQMAYIVKETCQGLKFLHNKKIIHRDIKSDNILLNSQGLVKITDFGFCVELTEKRSKRATMVGTPYWMAPEI--VNQK
| ||  .     ||    ||.| |.||. .|| |||..||... .|||||  ||||..|| ||. |||   ..|   .||   .|||||||||.  |..|
LQDIYHV-----TG----PLSELQIAYVCRETLQGLHYLHSMGKMHRDIKGANILLTDQGDVKLADFGVSAQITATIAKRKSFIGTPYWMAPEVAAVERK

-GYDEKVDVWSLGIMLIEMIEGEPPYLNEDPLKALYLIANNG--SPKLRHPESVSKQTKQFLDACLQVNVESRASVRKLLTFEFL
 ||..  |.|..||  ||. |  ||  .  |..||.|..  .   |||.  .  |..  .|.  .|  |   | .  |||. .|.
GGYNQLCDIWAVGITAIELAELQPPMFDLHPMRALFLMTKSNFQPPKLKDKHKWSQTFHHFVKMALTKNPKKRPTAEKLLQHPFV
Kinase SKM1.AA SLK 404-639 35 1.1e-60 203.41 In-house 28-259 (259) Show / Hide 
Range on Protein: 404-639
Range on HMM: 28-259/259
Sequence Identity: 35% (86 aa)

AIKQIRLSEQPKKQLIMNELLVMNDSRQENIVNFLEAYIIDDEELWVIMEYMEGGCLTDILDAVARSNTGEHSSPLNENQMAYIVKETCQGLKFLHNKKI
| | | . .. . .  | |. .. .    |||. .||| .|. .||...|. .|| .  |.  . .        || |.|..|. |..|..|..||..|.
AAKMIEIKDEEELEDYMVEIDILSECKHPNIVKLYEAYYYDN-KLWMMIEFCDGGAVDNIMVELEH--------PLTEDQIQYVCKHMCEALNWLHSNKV

IHRDIKSDNILLNSQGLVKITDFGFCVELTEKRSKRATMVGTPYWMAPEIV-----NQKGYDEKVDVWSLGIMLIEMIEGEPPYLNEDPLKALYLIANNG
||||.|  |||.  .| |.. |||    ..... || | .|||||||||.|       . || |.|.||||| |||| ..|||. . .|.. |  |.   
IHRDLKAGNILMTMDGDVRLADFGVSAKNKHTMQKRDTFIGTPYWMAPEVVMCETFKDQPYDYKADIWSLGITLIEMAQMEPPHHEMNPMRVLLKIQKSE

SPKLRHPESVSKQTKQFLDACLQVNVESRASVRKLLTFEFL
 |.|  |   ||. | ||  ||. ... | .  .|.  ...
PPTLEQPSHWSKEFKDFLKKCLVKDPQNRWTTAQLMQHQWV
Kinase SKM1.AA STE11 400-639 29 2.5e-60 206.75 In-house 24-303 (303) Show / Hide 
Range on Protein: 400-639
Range on HMM: 24-303/303
Sequence Identity: 29% (85 aa)

GERVAIKQIRLSEQPKK--------QL------IMNELLVMNDSRQENIVNFLEAYII--DDEELWVIMEYMEGGCLTDILD-AVARSNTGEHSSP--LN
||..|.|||..  . .         |       |. |. .|   . .||| .. . .   ..... ..|||..|| | ..|.             |  ..
GELMAVKQIEIQNNNQMKEDQEKEYQSHKMHKAIQEEIKLMKHLNHKNIVRYYGCCLHDNQNDHVNIFMEYCPGGSLSSMLRHK---------WGPMKFD

ENQMAYIVKETCQGLKFLHNKKIIHRDIKSDNILLNSQGL-VKITDFGFCVELTEKRSKRAT----------MVGTPY--------WMAPEIVNQKG---
|. . . .|  ..||..|| ..||||||| .||||.|.|  .|..||| .. | .  .. ..          | ||||        |||||...| |   
EMVIRKYTKQILEGLQYLHSHGIIHRDIKGANILLDSDGNVCKLADFGCAKRLAWICTCTHNMNMTQNHCKSMTGTPYNSMMGTPMWMAPEVIKQEGRDG

YDEKVDVWSLGIMLIEMIEGEPPYLNED--PLKALYLIANNGSPKLRHPESVS------KQTKQFLDACLQVNVESRASVRKLLTFEFL
|. |.|.||||   |||. | ||. | |  .  |.. |. .  |    ||..|       ....||. |.. . . |.... ||   |.
YGRKADIWSLGCTVIEMATGKPPWHNYDHNHMAAMFKIGMGHKPHPPIPEHMSPISWISEECRDFLRHCFEHDPKKRPTANQLLQHPFI
Kinase SKM1.AA PAKL 479-639 45 1.4e-56 194.24 In-house 95-256 (256) Show / Hide 
Range on Protein: 479-639
Range on HMM: 95-256/256
Sequence Identity: 45% (73 aa)

LNENQMAYIVKETCQGLKFLHNKKIIHRDIKSDNILLNSQGLVKITDFGFCVELTEKRS-KRATMVGTPYWMAPEIVNQKGYDEKVDVWSLGIMLIEMIE
||| | . |.. |  ||  || | |||||||. |||||  . ||| |||    |    .     |.||||||||||.|.. |. |.|.||||| .||| .
LNEKQISVILQQTLKGLHYLHSKNIIHRDIKAANILLNEDCQVKIADFGVSQQLQDEYDGQANQMIGTPYWMAPEIINKQNYNNKCDIWSLGITAIEMAD

GEPPYLNEDPLKALYLIANNGSPKLRHPESVSKQTKQFLDACLQVNVESRASVRKLLTFEFL
|.||     | .|.| | |   |..  |   |.    ||. |..   | |.|.  ||.  |.
GFPPHYDMPPMRAMYMIPNWPPPTFSNPKHWSPCFNDFLAQCCVKDPEKRWSPIDLLCHPFI
Kinase SKM1.AA TyrKc 360-638 21 8.5e-29 102.9 SMART 1-280 (280) Show / Hide 
Range on Protein: 360-638
Range on HMM: 1-280/280
Sequence Identity: 21% (69 aa)

FQLVEKAGQGASGAVYLSKRIKLPQENDPRFLKSHCHRVVGERVAIKQIRLSEQPKKQLIMNELLVMNDS--RQENIVNFLEAYIIDD-------EELWV
 .| .| | || | ||. . .                    . ||.| .. .    .. .|.|. .|     . .|||... ......       | |..
ITLGKKLGEGAFGEVYKGTWK--------------------IQVAVKMLKEDA---REDFMREARIMCKLGGHHPNIVRLY-GVCTQQGRNFMYIEPLMI

IMEYMEGGCLTDILDAVARSNTGEHSSPLNENQMAYIVKETCQGLKFLHNKKIIHRDIKSDNILLNSQGLVKITDFGFCVELTEK----RSKRATMV---
.||||..|.| | | .  .         |.  .. ..    ..|  .|| |..||||.   |.|..... |||.||| . .....     ||   ..   
VMEYMPHGDLKDYLRKHRPK--------LCMKDLLSFCWQIACGMEYLHSKNCIHRDLAARNCLVGENHTVKISDFGLSRDIYDDDQQGESKDYYRKKEH

-GTP-----YWMAPEIVNQKGYDEKVDVWSLGIMLIEMIE-GEPPYLN-----EDPLKALYLIANNGSPKLRHPES--------VSKQTKQFLDACLQVN
 |.       |||||  | . . .| |||| |... |.   |..|| .      ..  .. .. . .   .. |..         ..   |    | . .
KGGKTMLPIRWMAPECINYGKFTTKSDVWSFGVCMWEIFTYGQQPYPGMIQQMMSNQEVIEYVKQGY--RMPQPPNDYPMSFVCCPDEMYQIMKQCWHED

VESRASVRKLLTFEF
 |.| . . .   .|
PEDRPTFSEI-HECF
Kinase SKM1.AA Pkinase_Tyr 360-527 24 2.6e-23 79.57 Pfam 1-156 (270) Show / Hide 
Range on Protein: 360-527
Range on HMM: 1-156/270
Sequence Identity: 24% (43 aa)

FQLVEKAGQGASGAVYLSKRIKLPQENDPRFLKSHCHRVVGERVAIKQI-RLSEQPK--KQLIMNELLVMNDS-RQENIVNFLEAYIIDDEE--LWVIME
 .. .| |.|| | ||. .                ..   .  ||.| .   . ..   ..  |.|. .|    . .|||... . . ..|   ....||
ITFGKKLGEGAFGEVYKGTWKG-------------DPDNTKIPVAVKMLKEGAMHEQNCREDFMREAKIMKQLGHHPNIVRLYGVCTDQGEPNQIYIVME

YMEGGCLTDILDAVARSNTGEHSSPLNENQMAYIVKETCQGLKFLHNKKIIHRDIKSDNILLNSQGLVKITDFG
||..|.| | | .       |   ||.  ..  .  . ..|. .|..|..||||.   |.|..... |||.|||
YMPHGDLLDYLRKHR-----EDKQPLTMKDLLQMCWQIAKGMEYLESKNCIHRDLAARNCLVTENNVVKICDFG
Kinase SKM1.AA Pkinase_Tyr 548-582 45 1.5e-08 29.62 Pfam 180-216 (270) Show / Hide 
Range on Protein: 548-582
Range on HMM: 180-216/270
Sequence Identity: 45% (17 aa)

WMAPEIVNQKGYDEKVDVWSLGIMLIEMIE-GEPP-Y
|||||  | . . .| |||| |. . |..  || | |
WMAPECINYGKFTTKSDVWSFGVLMWEIFTYGEQPTY
Kinase SKM1.AA MST 360-375 62 0.001084 7.52 In-house 1-16 (254) Show / Hide 
Range on Protein: 360-375
Range on HMM: 1-16/254
Sequence Identity: 62% (10 aa)

FQLVEKAGQGASGAVY
| .||| |||. | ||
FDIVEKLGQGSYGSVY
Kinase SKM1.AA PAKL 360-375 56 0.002869 8.43 In-house 1-16 (256) Show / Hide 
Range on Protein: 360-375
Range on HMM: 1-16/256
Sequence Identity: 56% (9 aa)

FQLVEKAGQGASGAVY
| . || |||. |.||
FEFQEKLGQGSYGSVY