Gene SLN1 (Bakers Yeast)

SLN1

Species: Bakers Yeast
Alias: SLN1
External Links: Saccharomyces Genome Database Link ,
Annotation:

Classification

Group: Atypical
Family: HisK

Sequence

Name Sequence Type Origin Length Description Download
SLN1.AA Protein Refseq_NP 1220 Synthetic lethal of N-end rule; Sln1p [Saccharomyces cerevisiae] Fasta, JSON

Protein domain

Protein domains of SLN1.AA. The domains are annotated by HMM profiles from Pfam and SMART, as well as in-house data which includes HMMs of each individual kinase group, family and subfamily. Here is domain list in details, including sequence identity, significance and alignment. In particular, you can find can find the best hit kinase group/family/subfamily, which is helpful to understand the relationship between kinases.Kinase domain and best hit kinase group/family/subfamily are highlighted in red and blue. Visualized by pviz.

Usage: Zoom in selected region by dragging mouse and zoom out by double-clicking.

Show/hide domain list
Domain Protein name Domain Name Range Identity (%) Significance Score Profile Source Profile Range (length) Alignment
HAMP SLN1.AA HAMP 335-374 22 0.171812 8.59 Pfam 1-40 (78) Show / Hide 
Range on Protein: 335-374
Range on HMM: 1-40/78
Sequence Identity: 22% (9 aa)

ITGTVIAIGVFVILLTLPLAHWAVQPIVRLQKATELITEG
. ...... .....| . ||.. ..|. ||..|.. | .|
LIWVMLIALLIALILAWWLARRITRPLRRLTQAMQRIADG
HAMP SLN1.AA HAMP 518-537 40 0.005597 14.07 Pfam 59-78 (78) Show / Hide 
Range on Protein: 518-537
Range on HMM: 59-78/78
Sequence Identity: 40% (8 aa)

SDELSDLTETFNTMTDALDQ
.||. .|...|| | |.| .
PDEIGQLARAFNQMRDRLRE
HisKA SLN1.AA HisKA 566-631 25 4e-16 60.82 SMART 1-89 (89) Show / Hide 
Range on Protein: 566-631
Range on HMM: 1-89/89
Sequence Identity: 25% (23 aa)

AKTVFIANISHELRTPLNGILGMTAISME-----------ETDVNKI------------RNSLKLIFRSGELLLHILTELLTFSKNVLQ
||. |.||.||||||||..|.|.. .  .           . |  ..            |  |. | |... ..... .||..|.   .
AKRQFLANMSHELRTPLTAIRGYAELLQDWYYKQRYHHWTDLDPEQRLPMLRREFNCEYREYLETIQREADRMQRLINDLLDLSRIEAG
HisKA SLN1.AA HisKA 566-631 34 9.8e-16 57.82 Pfam 1-69 (69) Show / Hide 
Range on Protein: 566-631
Range on HMM: 1-69/69
Sequence Identity: 34% (24 aa)

AKTVFIANISHELRTPLNGILGMTAISME--ETDVNK-IRNSLKLIFRSGELLLHILTELLTFSKNVLQ
||. |.||.||||||||..|.|.. .  .  . |  . .|  |. | |... ..... .||.||.   .
AKRQFLANMSHELRTPLTAIRGYAELLQDYTDLDPEQMRREYLETIQREAQRMQRLINDLLDFSRIEAG
HATPase_c SLN1.AA HATPase_c 680-928 17 5.2e-39 136.84 SMART 1-130 (130) Show / Hide 
Range on Protein: 680-928
Range on HMM: 1-130/130
Sequence Identity: 17% (50 aa)

GDSNRIIQIVMNLVSNALKFTPV-------------DGTVDVRMKLLGEYDKELSEKKQYKEVYIKKGTEVTENLETTDKYDLPTLSNHRKSVDLESSAT
|| .|. |.. ||..||.|.||              .|...|| .                                                       
GDPDRLRQVLWNLLDNAIKHTPEGHADPDLHDGKPGGGRITVRVH-------------------------------------------------------

SLGSNRDTSTIQEEITKRNTVANESIYKKVNDREKASNDDVSSIVSTTTSSYDNAIFNSQFNKAPGSDDEEGGNLGRPIENPKTWVISIEVEDTGPGIDP
                                                                                       .|.|||.||||.|
---------------------------------------------------------------------------------------RITVEDNGPGIPP

------SLQESVFHPFVQGDQ--------TLSRQYGG--TGLGLSICRQLANMMHGTMKLESKVGVGSKFTFTLPLNQ
       ... .|.||...|.          ||.|||  ||||||||........||...|      ..||||||| .
EMHKSIEDIPRIFEPFYRTDDSPSRMCPDSRSRKYGGGLTGLGLSICKRIVEQHGGTIWVE------TTFTFTLPLER
Kinase SLN1.AA HATPase_c 853-927 45 1.4e-29 105.19 Pfam 38-120 (120) Show / Hide 
Range on Protein: 853-927
Range on HMM: 38-120/120
Sequence Identity: 45% (38 aa)

ISIEVEDTGPGIDP------SLQESVFHPFVQGDQ-TLSRQYGG--TGLGLSICRQLANMMHGTMKLESKVGVGSKFTFTLPLN
..|.|||.||||.|       ... .|.||...|.    |.|||  |||||.|||... ...||. .||..| |..||||||| 
VRITVEDNGPGIPPEMHSIAEDIPRIFEPFYRTDPDSR-RKYGGGLTGLGLYICRRIVEQHGGTIWVESEPGGGTTFTFTLPLE
Kinase SLN1.AA HisK 680-927 17 7e-27 93.59 In-house 1-164 (164) Show / Hide 
Range on Protein: 680-927
Range on HMM: 1-164/164
Sequence Identity: 17% (50 aa)

GDSNRIIQIVMNLVSNALKFT-----PVDGTVDVRMKLLGEYDKELSEKKQYKEVYIKKGTEVTENLETTDKYDLPTLSNHRKSVDLESSATSLGSNRDT
 | ||| ||..||.|||||||     |  |.. .  ..  ...  .                                                      
SDPNRIKQILINLISNALKFTQKGGIPFQGYIKIKVEQINTQNN-I------------------------------------------------------

STIQEEITKRNTVANESIYKKVNDREKASNDDVSSIVSTTTSSYDNAIFNSQFNKAPGSDDEEGGNLGRPIENPKTW-------VISIEVEDTGPGIDPS
                                           | |.||......               . .           .| | |.||| |....
------------------------------------------KY-NSIFIQKIQEN--------------M-V---QEQLQQKNLIQISVQDTGCGMPEE

LQESVFHPFVQGD------------QTLSRQYGGTGLGLSICRQLANMMH--------GTMKLESKVGVGSKFTFTLPLN
.|.  | .| ..|            |  .    | ||||.||..|| ..         .  ...|.||.||.|.| .  |
QQKKIFKMFGNIDDQHQMIKKTFNHQNKKNNQHGCGLGLTICNNLAKGLGPEHNQNGNRGIQVQSEVGKGSTFSFYIYNN
Kinase SLN1.AA HATPase_c 680-716 43 3.4e-08 30.75 Pfam 1-37 (120) Show / Hide 
Range on Protein: 680-716
Range on HMM: 1-37/120
Sequence Identity: 43% (16 aa)

GDSNRIIQIVMNLVSNALKFTPVDGTVDVRMKLLGEY
|| .|. |.| |||.||.|.|| .|...|| .  ...
GDPDRLHQVVWNLVDNAIKHTPEGGHITVRVHRDDDH
Response_reg SLN1.AA Response_reg 1090-1207 30 1.2e-39 142.84 Pfam 1-115 (115) Show / Hide 
Range on Protein: 1090-1207
Range on HMM: 1-115/115
Sequence Identity: 30% (37 aa)

ILVVEDNHVNQEVIKRMLN-LEGIENIELACDGQEAFDKVKELTSKGENYNMIFMDVQMPKVDGLLSTKMIRRDLG-YTSPIVALTAFADDSNIKECLES
.|.|.|.....|.....|.  ||.|....| ||.|| ....|..     . .|.||..||..|||  ...||| .. .. ||...||..|.. . |.|. 
VLIVDDHPLMREGLRQILEQKEGYEVVAEADDGEEALEWWQEHH-----PDLIIMDINMPGMDGLELCRRIRRQHPHPQTPIIMCTAHGDEDDAVEALQA

GMNGFLSKPIKRPKLKTILT
|.|....||... .|.... 
GANDYITKPFDPDELHAAIR
REC SLN1.AA REC 1088-1206 25 3.3e-37 130.85 SMART 1-150 (150) Show / Hide 
Range on Protein: 1088-1206
Range on HMM: 1-150/150
Sequence Identity: 25% (40 aa)

VKILVVEDN----HVNQEVIK------RMLNLEGIE-------NIELACDGQ-------EAFDKVKELTSKG--------ENYNMIFMDVQMP-------
 .||.|.|.    .|..|...      |.|  ||.|       ... | ||.       ||.....|. .|.        |..  |.||..||       
MRILIVDDDPAMAPVIREMLRNYTVIQRLLEKEGYENKMWMVEVVDEA-DGETLMNEIWEALELLQEHRDKKEDATTDQSEPPDLIIMDIMMPGDPFEDG

KVDGLLSTKMIRRDLGYTSPIVALTAFADDSNIKECLESGMNGFLSKPIKRPKLKTIL
..||.  ...||       ||..|||..|.. . ..||.|......||...  |   .
GMDGIELCRRIR-------PIIMLTAHDDEEDRVRALEAGADDYITKPFDPEELLARI