SPS1

Species: Bakers Yeast
Alias: SPS1
External Links: Saccharomyces Genome Database Link ,
Annotation:

Classification

Group: STE
Family: STE20
Subfamily: YSK

Sequence

Name Sequence Type Origin Length Description Download
SPS1.kin_dom Protein Kinase Domain Sugen global kinase HMM prediction 255 Kinase domain by global Sugen HMM Fasta, JSON
SPS1.AA Protein Refseq_NP 490 `dispensable for mitosis, involved in middle/late stage of meiosis, required for spore wall formation; Sps1p [Saccharomyces cerevisiae]` Fasta, JSON

Protein domain

Protein domains of SPS1.AA. The domains are annotated by HMM profiles from Pfam and SMART, as well as in-house data which includes HMMs of each individual kinase group, family and subfamily. Here is domain list in details, including sequence identity, significance and alignment. In particular, you can find can find the best hit kinase group/family/subfamily, which is helpful to understand the relationship between kinases.Kinase domain and best hit kinase group/family/subfamily are highlighted in red and blue. Visualized by pviz.

Usage: Zoom in selected region by dragging mouse and zoom out by double-clicking.

Domain Protein name Domain Name Range Identity (%) Significance Score Profile Source Profile Range (length) Alignment
Kinase SPS1.AA YSK 18-272 56 3.4e-216 657.94 In-house 1-257 (257) Show / Hide
Range on Protein: 18-272
Range on HMM: 1-257/257
Sequence Identity: 56% (145 aa)

YSIQSCIGRGNFGDVYKAVDRVTQEIVAIKVVNLEHSDEDIELLAQEIFFLAELKSPLITNYIATMLEDVSMWIVMEYCGGGSCSDLLKRSYVNGLPEEK
...|.|||||.||.|||..|..||..||||...|||....||...|||.||....||.||.|....|.|...||.|||||||||.||.|..||....|..
FTKQECIGRGSFGEVYKGIDNRTQRVVAIKIIDLEHAEDEIEDIQQEIQFLSQCDSPYITKYYGSYLKDTKLWIIMEYCGGGSCLDLMKPKYVGQFDEKY

VSFIIHEVTLGLKYLHEQRKIHRDIKAANILLNEEGMVKLGDFGVSGHIR-STLKRDTFVGTPYWMAPEVVCCEVDGYNEKADIWSLGITTYELLKGLPP
...|..|...||.|||..|||||||||||.||.|.|.|||.||||.|.|. ...||.|||||||||||||.|.||..|..||||||||||.||..||.||
IAIILREILKGLDYLHSERKIHRDIKAANVLLSEHGDVKLCDFGVAGQITDTQIKRNTFVGTPYWMAPEVICQEVSYYDFKADIWSLGITAYEMAKGEPP

LSKYDPMKVMTNLPKRKPPKLQG-PFSDAAKDFVAGCLVKTPADRPSAYNLLSFEFV
...|.||.||...||..||||.| ..|...|.||..||.|.|..||||..||...|.
YCDYHPMRVMFLIPKNNPPKLEGRSYSKMFKEFVECCLNKDPEQRPSAKELLKHKFI

Kinase SPS1.AA STE20 18-272 43 8.9e-136 457.37 In-house 1-288 (288) Show / Hide
Range on Protein: 18-272
Range on HMM: 1-288/288
Sequence Identity: 43% (125 aa)

YSIQSCIGRGNFGDVYKAVDRVTQEI----VAIKVVNLEHSD---EDIELLAQEIFFLAELKSPLITNYIATMLED----VSMWIVMEYCGGGSCSDLLK
| .. .||.|..|.|||| .. |.|.    ||||..|||. |   ...|.. .|| .....|.| |..|. . | |     . |||||||||||..|..|
YELLEKIGQGSYGKVYKAYHKPTGEYCNQRVAIKKMNLEKCDNEQDEWEDIQKEISIMKQCKHPNIVKYYGSYLKDDTCDDELWIVMEYCGGGSLTDIMK

RSYVNG-------LPEEKVSFIIHEVTLGLKYLHEQRKIHRDIKAANILLNEEGMVKLGDFGVSGHIRS----T--LKRDTFVGTPYWMAPEVVCCEV--
.... |       . || ...| .||  ||.|||....|||||||.||||.|.| ||| ||||.. . .    |   ||.|||||||||||||..|.   
HCMKCGKNHKGHPMNEEQIAYICREVLQGLDYLHSNHIIHRDIKADNILLTEDGEVKLADFGVCAQLTKHGRDTMQFKRNTFVGTPYWMAPEVIQCMEGP

-DGYNEKADIWSLGITTYELLKGLPPLSKYDPMKVMTNLP--KRKPPKLQG----PFSDAAKDFVAGCLVKTPADRPSAYNLLSFEFV
  ||..|.||||||||. |...| ||.... ||..|   |  ...||.|..     .|.  .|||. ||.| |..||.|  ||. .|.
DKGYDYKCDIWSLGITAIEMAEGEPPYFDMHPMRAMFMIPKNQNPPPTLKDDKPHKWSPEFHDFVDKCLQKDPEKRPTASQLLKHPFI

Kinase SPS1.AA STE 18-272 30 1.2e-112 380.56 In-house 1-359 (359) Show / Hide
Range on Protein: 18-272
Range on HMM: 1-359/359
Sequence Identity: 30% (112 aa)

YSIQSCIGRGNFGDVYKAVDRV---------------TQEIVAIKVVNLEHSD----------------EDIELLAQEIFFLAELK--SPLITNYIATML
. ....||.|.|| ||||...                |.||.|||..|||...                |... . .|| .. ...  .| | .|. . .
WEGIEKIGKGAFGTVYKAMNHKNCNIHKTGEVENNGETGEIMAIKQMNLENCNNKDENQENQELENKNHEEMQQILKEIKIMKKCNHMHPNIVKYYGCYF

ED-------VSMWIVMEYCGGGSCSDLLKRSYVNGLP------------EEKVSFIIHEVTLG-LKYLHEQRKIHRDIKAANILLNEEGMVKLGDFGVSG
 .        . ||.|||..|||..|..|. |  | |            |. ...|....  | |.|||....||||||.|||||     ||| ||||.|
KEGHNHKNDDELWICMEYMDGGSLDDIIKHKYGCGKPLNHNRQHQHRFPESQIAYICRQILKGLLYYLHSHHIIHRDIKPANILL-----VKLCDFGVCG

HIRSTL-----------------KRDTFVGTPYWMAPEVVCCE----VDGYNEKADIWSLGITTYELLKGLPPLSKYDPMKVMTNLPKR-----------
 . ...                 ||.|||||| ||||||. ..    ..||..|.||||||.|  |.. | ||.... ||..| . |.            
QLTDSMANIQSNNIIDCIETMQQKRNTFVGTP-WMAPEVIQQNGQGRDKGYDTKCDIWSLGCTIIEMATGKPPWHDMHPMRAMFMIPFNYHMQQQFEQLC

----KPPKLQGP-------------------FSDAAKDFVAGCLVKTPADRPSAYNLLS--FEFV
    .||.|. .                   .|.  |||.. ||.| | .||.|  ||.   .|.
IVNGPPPPLPDHLSQNEMISYGGSGTTYPHKWSPEFKDFINKCLQKDPNKRPTASQLLKSEHPFI

Kinase SPS1.AA MST 18-272 44 1e-99 317.65 In-house 1-254 (254) Show / Hide
Range on Protein: 18-272
Range on HMM: 1-254/254
Sequence Identity: 44% (115 aa)

YSIQSCIGRGNFGDVYKAVDRVTQEIVAIKVVNLEHSDEDIELLAQEIFFLAELKSPLITNYIATML--EDVSMWIVMEYCGGGSCSDLLKRSYVNGLPE
..|  ..|.|..| ||||... | .|||||.|.    .||.. .  || .. . ||. |  | .  .   .   ||||||||.|| .|. |      | |
FDIVEKLGQGSYGSVYKAIHKQTGKIVAIKMVPV---NEDLQEIIKEISIMQQCKSKYIVKYYGSYFDAKNNHCWIVMEYCGMGSVCDIMKI-TQRTLNE

EKVSFIIHEVTLGLKYLHEQRKIHRDIKAANILLNEEGMVKLGDFGVSGHIRS-TLKRDTFVGTPYWMAPEVVCCEVDGYNEKADIWSLGITTYELLKGL
.  . |   . .||.|||  .||||||||.|||||.||  || ||||||     . ||.|..||||||||||   .  .|. ||||||||||  |.  | 
QQIACILYDTLQGLQYLHDNKKIHRDIKAGNILLNHEGECKLADFGVSGQLTDTMAKRNTVIGTPYWMAPEVI--QEIKYDCKADIWSLGITAIEMAEGM

PPLSKYDPMKVMTNLPKRKPPKLQGP--FSDAAKDFVAGCLVKTPADRPSAYNLLSFEFV
||.|   || .|   |.. ||... |  .|.   |||. ||.| | .|..|  ||. .|.
PPYSDIHPMRAMFMIPQKPPPTFKDPEQWSQEFNDFVCKCLQKNPEQRWTAEQLLQHPFI

Kinase SPS1.AA S_TKc 18-272 33 4.1e-94 319.88 SMART 1-231 (231) Show / Hide
Range on Protein: 18-272
Range on HMM: 1-231/231
Sequence Identity: 33% (90 aa)

YSIQSCIGRGNFGDVYKAVDRVTQEIVAIKVVNLEHSDEDIELLAQEIFFLAELKSPLITNYIATMLEDVSMWIVMEYCGG--GSCSDLLKRSYVNG---
| |   ||.| || |||.... |..|||||...        | . .||  | . . | | ... .. .  ....|||||.|  |.  |..|.   .|   
YEILRKIGKGAFGKVYKCRHKKTGRIVAIKIIK--------EHIRREIQILKK-HHPNIVKLYDVFQD-DHLYMVMEYCDGDLGDLFDYIKKRGRHGLRF

-LPEEKVSFIIHEVTLGLKYLHEQRKIHRDIKAANILLNEEGMVKLGDFGVSGHIRSTLKRDTFVGTPYWMAPEVVCCEVDGYNE-KADIWSLGITTYEL
 .||  . |..... ..|.|.|... ||||.| .||||.|   .|..|||.. ..      .||.|||..|||||.     ||.  |.|.||.|.. ||.
PFPE-HARFYMYQICCALEYCHSHGIIHRDLKPENILLDE--HIKICDFGLARQL------TTFCGTPWYMAPEVL-----GYGKCKCDWWSCGCILYEM

LKGLPPLSKYDPMKVMTNLPKRKPPKLQGPFSDAAKDFVAGCLVKTPADRPSAYNLLS-------FEFV
| | || .    |..| .. .          |. ||||. .||.| |..||.|  .|         ...
LCGYPPFP---QMQMMFKKIG----------SPEAKDFIRKCLQKDPEKRPTA-EALQDEWDIKCHPWF

Kinase SPS1.AA FRAY 18-272 38 1e-82 256.67 In-house 1-277 (277) Show / Hide
Range on Protein: 18-272
Range on HMM: 1-277/277
Sequence Identity: 38% (107 aa)

YSIQSCIGRGNFGDVYKAVDRVTQEIVAIKVVNLEHSD-EDIELLAQEIFFLAELKSPLITNYIATMLEDVSMWIVMEYCGGGSCSDLLKRSYVNGLP--
|  |  || |  . |.||.    || .|||..|||. .   .. |. ||      . | .  |    ..  ..|.|| | ..|||.|..|...  | |  
YELQEVIGEGATAVVHKAYCIPRQENCAIKRINLEKCQNTSMDELIKEIQAMCQCHHPNVVHYHTSFVVNEELWLVMRYLECGSCLDIMKFKMPQGEPHK

-----EEKVSFIIHEVTLGLKYLHEQRKIHRDIKAANILLNEEGMVKLGDFGVSGHIRS--TLKRD----TFVGTPYWMAPEVVCCEVDGYNEKADIWSL
     |  .  |  ||  || |.|.  .||||||| |||. |.| . . |||||. . .   | |.    |||||| ||||||.  .| ||. ||||||.
QGVFDEHVIATILKEVLKGLCYFHKNGQIHRDIKAGNILIGEDGTIQIADFGVSAWLATGGDLSRCCVRHTFVGTPCWMAPEVM-EQVHGYDFKADIWSF

GITTYELLKGLPPLSKYDPMKVMTNLPKRKPPKLQGP---------FSDAAKDFVAGCLVKTPADRPSAYNLLSFEFV
|||  || .| .|  || ||||. ..    || |..          ..  .|. .  || | |. || |  ||  .| 
GITAIELATGKAPYHKYPPMKVLMLTLQNDPPSLETDEDDKDMYKKYGHSFKKMIEKCLQKDPSKRPTASELLKHKFF

Kinase SPS1.AA KHS 18-272 42 5.2e-82 275.62 In-house 1-258 (258) Show / Hide
Range on Protein: 18-272
Range on HMM: 1-258/258
Sequence Identity: 42% (111 aa)

YSIQSCIGRGNFGDVYKAVDRVTQEIVAIKVVNLEHSDEDIELLAQEIFFLAELKSPLITNYIATMLEDVSMWIVMEYCGGGSCSDLLKRSYVNGLPEEK
| .   .| | .|||||| | ...|..|.||. .|  ..|.... |||. . . . | |  |.   |    .||.||||||||  |. .      | | .
YELLQRVGSGTYGDVYKARDIQSDELAAVKVIKME-PGDDFAVIQQEIMMMKDCRHPNIVAYFGSYLRRDKLWICMEYCGGGSLQDIYH--VTGPLSELQ

VSFIIHEVTLGLKYLHEQRKIHRDIKAANILLNEEGMVKLGDFGVSGHIRSTL-KRDTFVGTPYWMAPEVVCCEVD-GYNEKADIWSLGITTYELLKGLP
.... .|.  ||.||| . |.||||| |||||...| ||| |||||..|  |. ||  |.|||||||||| . |   |||.  |||..|||  ||    |
IAYVCRETLQGLHYLHSMGKMHRDIKGANILLTDQGDVKLADFGVSAQITATIAKRKSFIGTPYWMAPEVAAVERKGGYNQLCDIWAVGITAIELAELQP

PLSKYDPMKVMTNLPKR--KPPKLQ--GPFSDAAKDFVAGCLVKTPADRPSAYNLLSFEFV
|.    ||...  . |   .||||.    .|..  .||  .|.| |  ||.|  ||. .||
PMFDLHPMRALFLMTKSNFQPPKLKDKHKWSQTFHHFVKMALTKNPKKRPTAEKLLQHPFV

Kinase SPS1.AA Pkinase 18-272 28 3.1e-77 267.69 Pfam 1-293 (293) Show / Hide
Range on Protein: 18-272
Range on HMM: 1-293/293
Sequence Identity: 28% (85 aa)

YSIQSCIGRGNFGDVYKAVDRVTQEIVAIKVVNLEHSDE--DIELLA-QEIFFLAELKSPLITNYIATMLEDVSMWIVMEYCGGG----SCSDLLKRSYV
| | ..||.|.|| |||.... |..|||.|.....| ..  |....  .||  ...|..| |  .. .. .. ....|||||.||    . .|...... 
YHIGRKIGSGSFGCVYKCHHKGTGKIVAVKIIKKRHEKSWKDQTHRRLSEIQIMKRLNHPNIVRLYDWFEDKDHIYMVMEYCEGGLYVMDLFDYISTWRH

NGL--PEEKVSFIIHEVTLGLKYLHEQRKIHRDIKAANILLNEEGMV----KLGDFGVSGH--IRSTLKRDTFVGTPYWMAPEVVCCEVDGYNEKADIWS
...  .|. . |.. ..  ||.|.|... ||||.| .|||....| .    |..|||.. .  . .    .||.|||..|||||.  .  .|  |.|.||
GCFYFSEWECKFYMYQILRGLEYCHSMGIIHRDLKPENILIDNNGHIDACVKICDFGLAKQFDY-NNS-MTTFCGTPWYMAPEVIR-GGQYYGPKVDMWS

LGITTYELLKGLPPLSKY----DPMKVMTNLPKRKPPKLQGPFS-----------------------DAAKDFVAGCLVKTPADRPSAYNLLSFEFV
.|.. ||.| | || .      . .  |  . ....|.|  ...                       ...|||. .|| | |..||.|  .|  ...
CGCILYEMLCGRPPFPGHCWHDN-HDQMQMICRIMGPPLHFDWPWWCSISYFFFRHWHFHWTFHNWSEECKDFIKWCLCKDPKKRPTAEQILQHPWF

Kinase SPS1.AA SLK 18-272 38 1.4e-73 247.55 In-house 1-259 (259) Show / Hide
Range on Protein: 18-272
Range on HMM: 1-259/259
Sequence Identity: 38% (101 aa)

YSIQSCIGRGNFGDVYKAVDRVTQEIVAIKVVNLEHSDEDIELLAQEIFFLAELKSPLITNYIATMLEDVSMWIVMEYCGGGSCSDLLKRSYVNGLPEEK
. |   .| | || ||||... .. . | |..... ..|..|    ||  |.|.| | | . . .   |  .|...|.|.||    ..      .| |..
WEIIGELGDGAFGKVYKAQHKEQKVFAAAKMIEIK-DEEELEDYMVEIDILSECKHPNIVKLYEAYYYDNKLWMMIEFCDGGAVDNIMVE-LEHPLTEDQ

VSFIIHEVTLGLKYLHEQRKIHRDIKAANILLNEEGMVKLGDFGVSGHIRSTL-KRDTFVGTPYWMAPEVVCCEV---DGYNEKADIWSLGITTYELLKG
. .. .... .|..||... ||||.|| |||.  .| |.| |||||   ..|. |||||.||||||||||| ||    . |  ||||||||||  |. ..
IQYVCKHMCEALNWLHSNKVIHRDLKAGNILMTMDGDVRLADFGVSAKNKHTMQKRDTFIGTPYWMAPEVVMCETFKDQPYDYKADIWSLGITLIEMAQM

LPPLSKYDPMKVMTNLPKRKPPKLQGP--FSDAAKDFVAGCLVKTPADRPSAYNLLSFEFV
 || .  .||.|.  . |  ||.|. |  .|   |||.  |||| |  |... .|.  ..|
EPPHHEMNPMRVLLKIQKSEPPTLEQPSHWSKEFKDFLKKCLVKDPQNRWTTAQLMQHQWV

Kinase SPS1.AA PAKA 18-272 38 1.4e-71 244.12 In-house 1-260 (260) Show / Hide
Range on Protein: 18-272
Range on HMM: 1-260/260
Sequence Identity: 38% (102 aa)

YSIQSCIGRGNFGDVYKAVDRVTQEI--VAIKVVNLEHSDEDIELLAQEIFFLAELKSPLITNYIATMLEDVSMWIVMEYCGGGSCSDLLKRSY---VNG
|   . || |  | ||.| .. |..   ||||. |..  .  .||.  ||  . | | . | ||| . | |  .|.|||| .||.  |...      .| 
YKFMEKIGQGASGEVYVATNIKTNQEENVAIKQMNMKN-QPKKELIINEILVMKECKHKNIVNYIDSYLVDDELWVVMEYMEGGCLTDVITQCCNIQCNY

LPEEKVSFIIHEVTLGLKYLHEQRKIHRDIKAANILLNEEGMVKLGDFGVSGHIRS-TLKRDTFVGTPYWMAPEVVCCEVDGYNEKADIWSLGITTYELL
..|. ..... |.  ||...|..  ||||||  ||||. .| ||. |||    .    .||.| |||||||||||.      |.|| ||||||| . |..
MDEGQIAYVCRECLQGLEFIHSKHRIHRDIKSDNILLGMDGSVKITDFGFCAQLTQEQQKRNTMVGTPYWMAPEVI--RRKQYDEKVDIWSLGIMAIEMI

KGLPPLSKYDPMKVM----TN-LPKRKPPKLQGPFSDAAKDFVAGCLVKTPADRPSAYNLLSFEFV
 | ||  ...| . |    ||  |..| |     .|. ..||.. || . . .|.||  ||...| 
EGEPPYLNEPPLRAMYLIATNGKPDIKDPDK---WSQEFCDFLDKCLCVDVDRRASAQELLHHPFL

Kinase SPS1.AA PAKL 18-272 40 2.4e-71 243.32 In-house 1-256 (256) Show / Hide
Range on Protein: 18-272
Range on HMM: 1-256/256
Sequence Identity: 40% (107 aa)

YSIQSCIGRGNFGDVYKAVDRVTQEIVAIKVVNLEHS-D-EDIELLAQEIFFLAELKSPLITNYIATMLED-VSMWIVMEYCGGGSCSDLLKRSYVNGLP
. .|   | | .| ||||. . |    ||||  .  | . .|||    ||  |   |.| |  |          .|| |.||  ||  |... |    | 
FEFQEKLGQGSYGSVYKAIHKDTNFPLAIKVIEIKESNEIKDIE---KEIQILKKCKCPNIVSYFGSIQQKLNHYWILMDYCSLGSINDMME-SCCKTLN

EEKVSFIIHEVTLGLKYLHEQRKIHRDIKAANILLNEEGMVKLGDFGVSGHIRSTLK--RDTFVGTPYWMAPEVVCCEVDGYNEKADIWSLGITTYELLK
|. .|.|.  . .|| ||| .  |||||||||||||| . ||. |||||  . ...       .|||||||||..      || |.||||||||  |.  
EKQISVILQQTLKGLHYLHSKNIIHRDIKAANILLNEDCQVKIADFGVSQQLQDEYDGQANQMIGTPYWMAPEII--NKQNYNNKCDIWSLGITAIEMAD

GLPPLSKYDPMKVMTNLPKRKPPKLQGP--FSDAAKDFVAGCLVKTPADRPSAYNLLSFEFV
|.||..   ||. |   | . ||..  |  .|    ||.| |.|| |  |.|.  ||.  | 
GFPPHYDMPPMRAMYMIPNWPPPTFSNPKHWSPCFNDFLAQCCVKDPEKRWSPIDLLCHPFI

Kinase SPS1.AA TAO 18-272 42 4e-71 231.5 In-house 1-254 (254) Show / Hide
Range on Protein: 18-272
Range on HMM: 1-254/254
Sequence Identity: 42% (109 aa)

YSIQSCIGRGNFGDVYKAVDRVTQEIVAIKVVNLE--HSDEDIELLAQEIFFLAELKSPLITNYIATMLEDVSMWIVMEYCGGGSCSDLLKRSYVNGLPE
..    || | || || | |. |.|.|||| ..     | |  . . .|. || ..| | . .| .  | .   |.|||||  || ||.|   .  .. |
FQDLREIGHGSFGAVYFARDKHTEEVVAIKKMSYSGKQSHEKWQDIIKEVRFLQQVKHPNCIEYKGCYLREHTCWLVMEYC-LGSASDILD-VHKKPMQE

EKVSFIIHEVTLGLKYLHEQRKIHRDIKAANILLNEEGMVKLGDFGVSGHIRSTLKRDTFVGTPYWMAPEVVCCEVDG-YNEKADIWSLGITTYELLKGL
. .  | |..  ||.|||. ..|||||||.|||| |.|.|||.|||    .      ..||||||||||||.    .| |..|.|.||||||  ||    
VEIAAICHGALQGLRYLHSHKMIHRDIKAGNILLTEHGQVKLADFGSASMVCPA---NSFVGTPYWMAPEVILAMDEGQYDGKVDVWSLGITCIELAERK

PPLSKYDPMKVMTNLPKRKPPKLQGP-FSDAAKDFVAGCLVKTPADRPSAYNLLSFEFV
|||     |  .  . .  .| || . .||. ..||  || | |..|||| ..| .|||
PPLFNMNAMSALYHIAQNDSPTLQQNEWSDCFHQFVDKCLQKMPQERPSAEECLRHEFV

Kinase SPS1.AA Pkinase_Tyr 18-163 26 1.5e-24 83.81 Pfam 1-158 (270) Show / Hide
Range on Protein: 18-163
Range on HMM: 1-158/270
Sequence Identity: 26% (42 aa)

YSIQSCIGRGNFGDVYKAVDR----VTQEIVAIKVVNLEHSDED---IELLAQEIFFLAEL-KSPLITNYIATML-EDVS--MWIVMEYCGGGSCSDLLK
 ..   .|.|.||.|||.. .     |.  ||.|..  |.....   .| . .|.  . .| . | | ....  . .. .  ..|||||. .|.  | |.
ITFGKKLGEGAFGEVYKGTWKGDPDNTKIPVAVKML-KEGAMHEQNCREDFMREAKIMKQLGHHPNIVRLYGVCTDQGEPNQIYIVMEYMPHGDLLDYLR

RS--YVNGLPEEKVSFIIHEVTLGLKYLHEQRKIHRDIKAANILLNEEGMVKLGDFGVS
.     . |. .    . ...  |. ||.... ||||. | |.|..|.. || .||| .
KHREDKQPLTMKDLLQMCWQIAKGMEYLESKNCIHRDLAARNCLVTENNVVKICDFGLA

Kinase SPS1.AA TyrKc 18-271 23 6.3e-19 70.12 SMART 1-280 (280) Show / Hide
Range on Protein: 18-271
Range on HMM: 1-280/280
Sequence Identity: 23% (68 aa)

YSIQSCIGRGNFGDVYKAVDRVTQEIVAIKVVNLEHSDEDIELLAQEIFFLAEL--KSPLITNYIATMLED-------VSMWIVMEYCGGGSCSDLLKRS
 .    .|.|.|| |||.. .   . ||.|... ..    .| . .|.  . .|  . | | . ..  ...         ..|||||. .|.. | |...
ITLGKKLGEGAFGEVYKGTWK---IQVAVKMLKEDA----REDFMREARIMCKLGGHHPNIVRLYGVCTQQGRNFMYIEPLMIVMEYMPHGDLKDYLRKH

YVNGLPEEKVSFIIHEVTLGLKYLHEQRKIHRDIKAANILLNEEGMVKLGDFGVSGHIRST--------LKRDTF-VGTP-----YWMAPEVVCCEVDG-
  . |. ..   . . .  |  |||... ||||. | |.|..|.. || .||| |  | .          .| .   |.       |||||.     .| 
RPK-LCMKDLLSFCWQIACGMEYLHSKNCIHRDLAARNCLVGENHTVKISDFGLSRDIYDDDQQGESKDYYRKKEHKGGKTMLPIRWMAPECI---NYGK

YNEKADIWSLGITTYELL-KGLPPLSK-----YDPMKVMTNLPKR-KPPKLQGP-------FSDAAKDFVAGCLVKTPADRPSAYNLLSFEF
...| |.|| |.. .|..  | .| .       ..  |. .. ..  .|. . .        .|.  .    |    |.|||.  ..   .|
FTTKSDVWSFGVCMWEIFTYGQQPYPGMIQQMMSNQEVIEYVKQGYRMPQPPNDYPMSFVCCPDEMYQIMKQCWHEDPEDRPTFSEI-HECF

Kinase SPS1.AA Pkinase_Tyr 181-229 27 0.005794 10.66 Pfam 180-228 (270) Show / Hide
Range on Protein: 181-229
Range on HMM: 180-228/270
Sequence Identity: 27% (14 aa)

WMAPEVVCCEVDGYNEKADIWSLGITTYELLK-GLPP-LSKYDPMKVMTNL
|||||.    .  ...| |.|| |.. .|..  |  |     ..  |.  .
WMAPECINYGK--FTTKSDVWSFGVLMWEIFTYGEQPTYPGMSNEEVYEYI